Open Access

Attitudes towards COVID‑19 vaccination in patients with cancer: A cross‑sectional study of 12 oncology centers

  • Authors:
    • Raluca Lazar
    • Cristina Marinela Oprean
    • Larisa Maria Badau
    • Geanina Miron
    • Loredana Draganescu
    • Tunde Torok‑Vistai
    • Iulia Coroian
    • Diana Sabau
    • Alexandru Iliescu
    • Loredana Aracs Tamas
    • Sorin Hosu
    • Razvan Curca
    • Alexandra Gatej
    • Amalia Hora
    • Andrei Ungureanu
    • Doru Parvu
    • Dan Valean
    • Lia Oxana Usatiuc
    • Radu Vidra
  • View Affiliations

  • Published online on: November 1, 2022     https://doi.org/10.3892/mco.2022.2595
  • Article Number: 162
  • Copyright: © Lazar et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Patients with cancer are a high‑priority population for COVID‑19 vaccination, as per guideline recommendations. The present cross‑sectional study was performed to assess the perception of patients with cancer from Romania regarding COVID‑19 vaccines. The study included 932 patients with solid and hematologic malignancies. This was a multicenter study including 12 oncology centers located in Western and Northwestern Romania. Between December 2021 and January 2022, patients with cancer completed an individual paper questionnaire regarding acceptance of the SARS‑CoV‑2 vaccination, type of vaccine, side effects and source of information. During the first year of the vaccination campaign in Romania, 58.05% (541/932) of the investigated patients received COVID‑19 vaccines. The vaccination rate was highest in the 61‑70 year age group (61.22%). The most frequently used vaccine was Pfizer‑BioNTech (72%). There was a statistically significant association between the rate of vaccination and the area of residence and level of education (P<0.001), with rural residence and a lower level of education being predictive factors for COVID‑19 vaccination hesitancy. Patients living in rural areas used non‑medical sources (e.g. mass media, social platforms) as their main source of information (53.40%, 204/382), whereas patients living in urban areas (64.90%, 357/550) used predominantly medical sources (e.g. recommendations from oncologists and general practitioners). The main source of information among non‑vaccinated patients was mass media (e.g. television, radio); 72.38% vs. 29.67% among vaccinated patients. For the latter, the primary source of information was the recommendations made by oncologists (59.70%) and general practitioners (56.76%). The most commonly reported side effect was injection site pain (20‑33% for the first dose and 5‑27% for the second dose). In conclusion, the present study confirmed that patients with cancer may be reluctant to receive a COVID‑19 vaccine, mainly due to the fear of its potential side effects. Although there is scientific evidence to support the efficacy and safety of vaccines, the primary source of information for patients may affect vaccine uptake, thus affecting the efforts to stop the pandemic. Furthermore, the present study revealed that non‑vaccinated patients preferred mass media as their main source of information, whereas vaccinated patients relied on the recommendations made by oncologists or general practitioners.

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December-2022
Volume 17 Issue 6

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Spandidos Publications style
Lazar R, Oprean CM, Badau LM, Miron G, Draganescu L, Torok‑Vistai T, Coroian I, Sabau D, Iliescu A, Tamas LA, Tamas LA, et al: Attitudes towards COVID‑19 vaccination in patients with cancer: A cross‑sectional study of 12 oncology centers. Mol Clin Oncol 17: 162, 2022
APA
Lazar, R., Oprean, C.M., Badau, L.M., Miron, G., Draganescu, L., Torok‑Vistai, T. ... Vidra, R. (2022). Attitudes towards COVID‑19 vaccination in patients with cancer: A cross‑sectional study of 12 oncology centers. Molecular and Clinical Oncology, 17, 162. https://doi.org/10.3892/mco.2022.2595
MLA
Lazar, R., Oprean, C. M., Badau, L. M., Miron, G., Draganescu, L., Torok‑Vistai, T., Coroian, I., Sabau, D., Iliescu, A., Tamas, L. A., Hosu, S., Curca, R., Gatej, A., Hora, A., Ungureanu, A., Parvu, D., Valean, D., Usatiuc, L. O., Vidra, R."Attitudes towards COVID‑19 vaccination in patients with cancer: A cross‑sectional study of 12 oncology centers". Molecular and Clinical Oncology 17.6 (2022): 162.
Chicago
Lazar, R., Oprean, C. M., Badau, L. M., Miron, G., Draganescu, L., Torok‑Vistai, T., Coroian, I., Sabau, D., Iliescu, A., Tamas, L. A., Hosu, S., Curca, R., Gatej, A., Hora, A., Ungureanu, A., Parvu, D., Valean, D., Usatiuc, L. O., Vidra, R."Attitudes towards COVID‑19 vaccination in patients with cancer: A cross‑sectional study of 12 oncology centers". Molecular and Clinical Oncology 17, no. 6 (2022): 162. https://doi.org/10.3892/mco.2022.2595