Positional advantages of supine MRI for diagnosis prior to breast‑conserving surgery

  • Authors:
    • Goro Kutomi
    • Hiroaki Shima
    • Daisuke Kyuno
    • Fukino Satomi
    • Asaka Wada
    • Yoko Kuga
    • Minoru Okazaki
    • Akira Okazaki
    • Hideji Masuoka
    • Toshihiko Mikami
    • Yuichi Yuyama
    • Takashi Matsuno
    • Tosei Ohmura
    • Hidekazu Kameshima
    • Toru Mizuguchi
    • Ichiro Takemasa
  • View Affiliations

  • Published online on: April 4, 2023     https://doi.org/10.3892/mco.2023.2640
  • Article Number: 44
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Abstract

The present study aimed to evaluate the rate of positive surgical margins for magnetic resonance imaging (MRI) performed in the supine position prior to breast‑conserving surgery (BCS). The rate of positive surgical margins and the clinicopathological factors were examined in consecutive patients with BCS who underwent preoperative MRI performed in the supine position at Sapporo Medical University Hospital (Sapporo, Japan) and related hospitals and clinics between January 2012 and December 2013. Of 1,175 eligible patients, 1,150 were included after excluding 25 patients with either bilateral breast cancer or stage IV disease. Positive margin was defined as no cancer seen on the resected margin. The primary endpoint was the rate of positive surgical margins when preoperative MRI was performed in the supine position and the secondary endpoint was identification of the factors that predict positive margins. Of the 1,150 female patients (median age, 55 years; range, 29‑97 years) who underwent BCS for breast cancer following MRI performed in the supine position, 215 (18.8%) had positive margins, which is similar to the rate with MRI in the prone position, and 930 (81.2%) had negative margins. The rate of positive surgical margins in patients of the human epidermal growth factor receptor 2 (HER2) type was significantly higher than that in the non‑HER2 type group (6.5 and 2.9%; χ2 P=0.0103). There was no increase in the rate of positive margins in breast cancers with a diameter of >T2. The rate of positive surgical margins following MRI performed in the supine position was 18.8%. Supine MRI appears to be suitable for informing on the extent of resection of breast cancer.
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May-2023
Volume 18 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Kutomi G, Shima H, Kyuno D, Satomi F, Wada A, Kuga Y, Okazaki M, Okazaki A, Masuoka H, Mikami T, Mikami T, et al: Positional advantages of supine MRI for diagnosis prior to breast‑conserving surgery. Mol Clin Oncol 18: 44, 2023
APA
Kutomi, G., Shima, H., Kyuno, D., Satomi, F., Wada, A., Kuga, Y. ... Takemasa, I. (2023). Positional advantages of supine MRI for diagnosis prior to breast‑conserving surgery. Molecular and Clinical Oncology, 18, 44. https://doi.org/10.3892/mco.2023.2640
MLA
Kutomi, G., Shima, H., Kyuno, D., Satomi, F., Wada, A., Kuga, Y., Okazaki, M., Okazaki, A., Masuoka, H., Mikami, T., Yuyama, Y., Matsuno, T., Ohmura, T., Kameshima, H., Mizuguchi, T., Takemasa, I."Positional advantages of supine MRI for diagnosis prior to breast‑conserving surgery". Molecular and Clinical Oncology 18.5 (2023): 44.
Chicago
Kutomi, G., Shima, H., Kyuno, D., Satomi, F., Wada, A., Kuga, Y., Okazaki, M., Okazaki, A., Masuoka, H., Mikami, T., Yuyama, Y., Matsuno, T., Ohmura, T., Kameshima, H., Mizuguchi, T., Takemasa, I."Positional advantages of supine MRI for diagnosis prior to breast‑conserving surgery". Molecular and Clinical Oncology 18, no. 5 (2023): 44. https://doi.org/10.3892/mco.2023.2640