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New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review)

  • Authors:
    • Hélène Simon
    • Daniel Henkel
    • Paul Chiron
    • Carole Helissey
  • View Affiliations / Copyright

    Affiliations: Clinical Research Unit, Department of Oncology, Military Hospital Begin, 94160 Saint‑Mandé, France, Unité de Formation et de Recherche 5, University of Paris 8 Vincennes‑St. Denis, 93200 Paris, France, Department of Urology, Military Hospital Begin, 94160 Saint‑Mandé, France
    Copyright: © Simon et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 51
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    Published online on: May 18, 2023
       https://doi.org/10.3892/mco.2023.2647
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Abstract

Nuclear medicine is an essential part of prostate cancer management concerning initial staging, patient follow‑up and even therapy. Prostate‑specific membrane antigen (PSMA) is a glutamate carboxypeptidase II transmembrane glycoprotein expressed by 80% of prostatic cells. The interest in this protein is due to its specificity for prostatic tissue. The use of 68GaPSMA PET/CT in the context of disease staging is thus well‑established and recommended, especially for high‑risk disease with metastases and lymph node involvement. However, the risk of false positives raises questions regarding its place in the management of patients with prostate cancer. The present study aimed to determine the use of PET‑PSMA in the care of patients with prostate cancer but also to assess its limits of use.
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Copy and paste a formatted citation
Spandidos Publications style
Simon H, Henkel D, Chiron P and Helissey C: New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review). Mol Clin Oncol 19: 51, 2023.
APA
Simon, H., Henkel, D., Chiron, P., & Helissey, C. (2023). New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review). Molecular and Clinical Oncology, 19, 51. https://doi.org/10.3892/mco.2023.2647
MLA
Simon, H., Henkel, D., Chiron, P., Helissey, C."New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review)". Molecular and Clinical Oncology 19.1 (2023): 51.
Chicago
Simon, H., Henkel, D., Chiron, P., Helissey, C."New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review)". Molecular and Clinical Oncology 19, no. 1 (2023): 51. https://doi.org/10.3892/mco.2023.2647
Copy and paste a formatted citation
x
Spandidos Publications style
Simon H, Henkel D, Chiron P and Helissey C: New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review). Mol Clin Oncol 19: 51, 2023.
APA
Simon, H., Henkel, D., Chiron, P., & Helissey, C. (2023). New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review). Molecular and Clinical Oncology, 19, 51. https://doi.org/10.3892/mco.2023.2647
MLA
Simon, H., Henkel, D., Chiron, P., Helissey, C."New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review)". Molecular and Clinical Oncology 19.1 (2023): 51.
Chicago
Simon, H., Henkel, D., Chiron, P., Helissey, C."New perspectives on metabolic imaging in the management of prostate cancer in 2022: A focus on radiolabeled PSMA‑PET/CT (Review)". Molecular and Clinical Oncology 19, no. 1 (2023): 51. https://doi.org/10.3892/mco.2023.2647
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