Therapeutic challenges of extrapulmonary dual organ system involvement in COVID‑19: A case report

Khalid,Karniza; Wahab,Suhaila Ab; Azni,Khaulah Karimah

doi:10.3892/mi.2021.24

November-December 2021 Volume 1 Issue 5

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November-December 2021 Volume 1 Issue 5

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Case Report Open Access

Therapeutic challenges of extrapulmonary dual organ system involvement in COVID‑19: A case report

Authors:
- Karniza Khalid
- Suhaila Ab Wahab
- Khaulah Karimah Azni
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Affiliations: Clinical Research Centre, Hospital Tuanku Fauziah, Ministry of Health Malaysia, 01000 Kangar, Perlis, Malaysia, Department of Internal Medicine (Infectious Disease), Hospital Tuanku Fauziah, Ministry of Health Malaysia, 01000 Kangar, Perlis, Malaysia, Department of Radiology, Hospital Tuanku Fauziah, Ministry of Health Malaysia, 01000 Kangar, Perlis, Malaysia

Copyright: © Khalid et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 24
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Published online on: December 7, 2021

https://doi.org/10.3892/mi.2021.24
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Abstract

Respiratory symptoms and signs remain the hallmark of coronavirus disease 2019 (COVID‑19) infection. However, extrapulmonary manifestations of COVID‑19 are not uncommon, and are likely to be underreported. The present study describes a clinical case of a 64‑year‑old patient with COVID‑19 with marked extrapulmonary manifestations in the setting of strong positive reactions with cycle threshold values of reverse transcription polymerase chain reaction for COVID‑19. He presented with asymptomatic bradycardia with wide pulse pressure, eventually requiring transvenous cardiac pacing. He later complained of lower abdominal pain associated with no bowel movements for four days. The computed tomography examination of the abdomen revealed circumferential wall thickening at the proximal ascending colon, suggestive of inflammatory changes and features of obstruction in the presence of inguinal hernia. Despite aggressive resuscitative efforts, the patient continued to deteriorate with multiorgan failure, and eventually succumbed to the disease after 6 days of hospitalization. The present case study deliberates the sharing of our clinical experience and therapeutic challenges in the management of COVID‑19 with complex extrapulmonary manifestation.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Therapeutic challenges of extrapulmonary dual organ system involvement in COVID‑19: A case report

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