Open Access

Segmental citrate anticoagulation for double‑filtration plasmapheresis: A case report and literature review

  • Authors:
    • Jin He
    • Chuncai Ma
    • Fangnan Wang
  • View Affiliations

  • Published online on: May 31, 2022     https://doi.org/10.3892/mi.2022.43
  • Article Number: 18
  • Copyright: © He et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Regional citrate anticoagulation (RCA) has been widely used in patients with high‑risk bleeding for anticoagulation in renal replacement therapy. However, scientific reports on the use of RCA in double‑filtration plasmapheresis (DFPP) are limited. In the available reports, anticoagulation was not performed in the plasma component separator. However, as demonstrated in the present study, during the treatment of a patient with anti‑neutrophil cytoplasmic antibody‑associated vasculitis, although RCA was used for DFPP, coagulation occurred in the plasma component separator, resulting in the interruption of treatment. Thus, segmental citrate anticoagulation (SCA) was used and the filter was successfully prevented from clotting again. The present study demonstrates that SCA can more effectively prevent the clogging of the plasma separator and the plasma component separator, thereby maintaining the continuity of treatment and avoiding treatment interruption.
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May-June 2022
Volume 2 Issue 3

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Spandidos Publications style
He J, Ma C and Wang F: Segmental citrate anticoagulation for double‑filtration plasmapheresis: A case report and literature review. Med Int 2: 18, 2022
APA
He, J., Ma, C., & Wang, F. (2022). Segmental citrate anticoagulation for double‑filtration plasmapheresis: A case report and literature review. Medicine International, 2, 18. https://doi.org/10.3892/mi.2022.43
MLA
He, J., Ma, C., Wang, F."Segmental citrate anticoagulation for double‑filtration plasmapheresis: A case report and literature review". Medicine International 2.3 (2022): 18.
Chicago
He, J., Ma, C., Wang, F."Segmental citrate anticoagulation for double‑filtration plasmapheresis: A case report and literature review". Medicine International 2, no. 3 (2022): 18. https://doi.org/10.3892/mi.2022.43