Efficacy of foam sclerotherapy with polidocanol for the management of oral venous malformations

Kato,Tomoki; Katayama,Yasuhiro; Fukuhara,Shizuko; Watanabe,Takuma; Yamanaka,Shigeki; Nakao,Kazumasa; Morimoto,Naoki

doi:10.3892/mi.2024.148

May-June 2024 Volume 4 Issue 3

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May-June 2024 Volume 4 Issue 3

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Article Open Access

Efficacy of foam sclerotherapy with polidocanol for the management of oral venous malformations

Authors:
- Tomoki Kato
- Yasuhiro Katayama
- Shizuko Fukuhara
- Takuma Watanabe
- Shigeki Yamanaka
- Kazumasa Nakao
- Naoki Morimoto
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Affiliations: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan, Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan, Department of Oral and Maxillofacial Surgery, Ama Municipal Hospital, Ama, Aichi 490‑1111, Japan

Copyright: © Kato et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 24
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Published online on: March 26, 2024

https://doi.org/10.3892/mi.2024.148
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Abstract

The present aimed to examine the effectiveness of polidocanol‑based foam sclerotherapy for oral venous malformations (OVMs). The present study performed a retrospective analysis of patients with OVMs who underwent sclerotherapy using polidocanol. Patients achieving the complete resolution of OVM were categorized as having a complete response (CR), those with a reduction in size from the initial diagnosis were categorized as having a partial response (PR), those with no change in size as stable disease (SD), and those with an increase in size as progressive disease (PD). A total of 16 patients, comprising 4 males and 12 females, underwent treatment with polidocanol foam therapy, covering 22 affected areas. The treatment administered resulted in CR in 6 cases and PR in 10 cases, with no instances of SD or PD. Apart from localized injection site pain or swelling, there were no severe side‑effects reported, such as circulatory dynamic changes or skin necrosis. On the whole, these findings underscore the effectiveness of foam sclerotherapy with polidocanol as a viable treatment for venous malformations in the oral and maxillofacial regions.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Efficacy of foam sclerotherapy with polidocanol for the management of oral venous malformations

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