|
1
|
Gilmore JH, Knickmeyer RC and Gao W:
Imaging structural and functional brain development in early
childhood. Nat Rev Neurosci. 19:123–137. 2018.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Mrzljak L, Uylings HB, Van Eden CG and
Judás M: Neuronal development in human pre-frontal cortex in
prenatal and postnatal stages. Prog Brain Res. 85:185–222.
1990.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Landing BH, Shankle WR, Hara J, Brannock J
and Fallon JH: The development of structure and function in the
postnatal human cerebral cortex from birth to 72 months: Changes in
thickness of layers II and III correlate to the onset of new
age-specific behaviors. Pediatr Pathol Mol Med. 21:321–342.
2002.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z,
Tsai HH, Wong M, Gupta N, Berger MS, Huang E, Garcia-Verdugo JM, et
al: Corridors of migrating neurons in the human brain and their
decline during infancy. Nature. 478:382–386. 2011.PubMed/NCBI View Article : Google Scholar
|
|
5
|
La Rosa C, Parolisi R and Bonfanti L:
Brain structural plasticity: From adult neurogenesis to immature
neurons. Front Neurosci. 14(75)2020.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Tierney AL and Nelson CA: Brain
development and the role of experience in the early years. Zero
Three. 30:9–13. 2009.PubMed/NCBI
|
|
7
|
Russ JB, Simmons R and Glass HC: Neonatal
encephalopathy: Beyond hypoxic-ischemic encephalopathy. NeoReviews.
22:e148–e162. 2021.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Liu L, Johnson HL, Cousens S, Perin J,
Scott S, Lawn JE, Rudan I, Campbell H, Cibulskis R, Li M, et al:
Global, regional, and national causes of child mortality: An
updated systematic analysis for 2010 with time trends since 2000.
Lancet. 379:2151–2161. 2012.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Gopagondanahalli KR, Li J, Fahey MC, Hunt
RW, Jenkin G, Miller SL and Malhotra A: Preterm hypoxic-ischemic
encephalopathy. Front Pediatr. 4(114)2016.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Sanchez RM, Koh S, Rio C, Wang C, Lamperti
ED, Sharma D, Corfas G and Jensen FE: Decreased glutamate receptor
2 expression and enhanced epileptogenesis in immature rat
hippocampus after perinatal hypoxia-induced seizures. J Neurosci.
21:8154–8163. 2001.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Babbo CCR, Mellet J, van Rensburg J,
Pillay S, Horn AR, Nakwa FL, Velaphi SC, Kali GTJ, Coetzee M,
Masemola MYK, et al: Neonatal encephalopathy due to suspected
hypoxic ischemic encephalopathy: Pathophysiology, current, and
emerging treatments. World J Pediatr. 20:1105–1114. 2024.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Rutherford M, Ramenghi LA, Edwards AD,
Brocklehurst P, Halliday H, Levene M, Strohm B, Thoresen M,
Whitelaw A and Azzopardi D: Assessment of brain tissue injury after
moderate hypothermia in neonates with hypoxic-ischaemic
encephalopathy: A nested substudy of a randomised controlled trial.
Lancet Neurol. 9:39–45. 2010.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Zhou T, Mo J, Xu W, Hu Q, Liu H, Fu Y and
Jiang J: Mild hypothermia alleviates oxygen-glucose
deprivation/reperfusion-induced apoptosis by inhibiting ROS
generation, improving mitochondrial dysfunction and regulating DNA
damage repair pathway in PC12 cells. Apoptosis. 28:447–457.
2023.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Shankaran S, Laptook AR, Ehrenkranz RA,
Tyson JE, McDonald SA, Donovan EF, Fanaroff AA, Poole WK, Wright
LL, Higgins RD, et al: Whole-body hypothermia for neonates with
hypoxic-ischemic encephalopathy. N Engl J Med. 353:1574–1584.
2005.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Azzopardi D, Strohm B, Marlow N,
Brocklehurst P, Deierl A, Eddama O, Goodwin J, Halliday HL,
Juszczak E, Kapellou O, et al: Effects of hypothermia for perinatal
asphyxia on childhood outcomes. N Engl J Med. 371:140–149.
2014.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Jacobs SE, Berg M, Hunt R, Tarnow-Mordi
WO, Inder TE and Davis PG: Cooling for newborns with hypoxic
ischaemic encephalopathy. Cochrane Database Syst Rev.
31(CD003311)2013.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Isaković J, Slatković F, Jagečić D,
Petrović DJ and Mitrečić D: Pulsating extremely low-frequency
electromagnetic fields influence differentiation of mouse neural
stem cells towards astrocyte-like phenotypes: In vitro pilot study.
Int J Mol Sci. 25(4038)2024.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Petrović DJ, Jagečić D, Krasić J, Sinčić N
and Mitrečić D: Effect of fetal bovine serum or basic fibroblast
growth factor on cell survival and the proliferation of neural stem
cells: The influence of homocysteine treatment. Int J Mol Sci.
24(14161)2023.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Jagečić D, Petrović DJ, Šimunić I,
Isaković J and Mitrečić D: The oxygen and glucose deprivation of
immature cells of the nervous system exerts distinct effects on
mitochondria, mitophagy, and autophagy, depending on the cells'
differentiation stage. Brain Sci. 13(910)2023.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Cornette L: Therapeutic hypothermia in
neonatal asphyxia. Facts Views Vis Obgyn. 4:133–139.
2012.PubMed/NCBI
|
|
22
|
Lemyre B and Chau V: Hypothermia for
newborns with hypoxic-ischemic encephalopathy. Paediatr Child
Health. 23:285–291. 2018.PubMed/NCBI View Article : Google Scholar : (In English,
French).
|
|
23
|
Shankaran S: Therapeutic hypothermia for
neonatal encephalopathy. Curr Treat Options Neurol. 14:608–619.
2012.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Wang J, Huang Y, Cai J, Ke Q, Xiao J,
Huang W, Li H, Qiu Y, Wang Y, Zhang B, et al: A
nestin-cyclin-dependent kinase 5-dynamin-related protein 1 axis
regulates neural stem/progenitor cell stemness via a metabolic
shift. Stem Cells. 36:589–601. 2018.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Hendrickson ML, Rao AJ, Demerdash ON and
Kalil RE: Expression of nestin by neural cells in the adult rat and
human brain. PLoS One. 6(e18535)2011.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Mizuno Y, Takeuchi T, Takatama M and
Okamoto K: Expression of nestin in Purkinje cells in patients with
Creutzfeldt-Jakob disease. Neurosci Lett. 352:109–112.
2003.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Dinsmore JH and Solomon F: Inhibition of
MAP2 expression affects both morphological and cell division
phenotypes of neuronal differentiation. Cell. 64:817–826.
1991.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Johnson GV and Jope RS: The role of
microtubule-associated protein 2 (MAP-2) in neuronal growth,
plasticity, and degeneration. J Neurosci Res. 33:505–512.
1992.PubMed/NCBI View Article : Google Scholar
|
|
29
|
DeGiosio RA, Grubisha MJ, MacDonald ML,
McKinney BC, Camacho CJ and Sweet RA: More than a marker: Potential
pathogenic functions of MAP2. Front Mol Neurosci.
15(974890)2022.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Taft WC, Yang K, Dixon CE, Clifton GL and
Hayes RL: Hypothermia attenuates the loss of hippocampal
microtubule-associated protein 2 (MAP2) following traumatic brain
injury. J Cereb Blood Flow Metab. 13:796–802. 2023.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Amoureux MC, Cunningham BA, Edelman GM and
Crossin KL: N-CAM binding inhibits the proliferation of hippocampal
progenitor cells and promotes their differentiation to a neuronal
phenotype. J Neurosci. 20:3631–3640. 2000.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Wu JQ, Habegger L, Noisa P, Szekely A, Qiu
C, Hutchison S, Raha D, Egholm M, Lin H, Weissman S, et al: Dynamic
transcriptomes during neural differentiation of human embryonic
stem cells revealed by short, long, and paired-end sequencing. Proc
Natl Acad Sci USA. 107:5254–5259. 2010.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Wang C, Wang X, Wang W, Chen Y, Chen H,
Wang W, Ye T, Dong J, Sun C, Li X, et al: Single-cell RNA
sequencing analysis of human embryos from the late Carnegie to
fetal development. Cell Biosci. 14(118)2024.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Huang R, Yuan DJ, Li S, Liang XS, Gao Y,
Lan XY, Qin HM, Ma YF, Xu GY, Schachner M, et al: NCAM regulates
temporal specification of neural progenitor cells via profilin2
during corticogenesis. J Cell Biol. 219(e201902164)2020.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Blaess S, Graus-Porta D, Belvindrah R,
Radakovits R, Pons S, Littlewood-Evans A, Senften M, Guo H, Li Y,
Miner JH, et al: Beta1-integrins are critical for cerebellar
granule cell precursor proliferation. J Neurosci. 24:3402–3412.
2004.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Belvindrah R, Hankel S, Walker J, Patton
BL and Müller U: Beta1 integrins control the formation of cell
chains in the adult rostral migratory stream. J Neurosci.
27:2704–2717. 2007.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Fujioka T, Kaneko N, Ajioka I, Nakaguchi
K, Omata T, Ohba H, Fässler R, García-Verdugo JM, Sekiguchi K,
Matsukawa N and Sawamoto K: β1 integrin signaling promotes neuronal
migration along vascular scaffolds in the post-stroke brain.
EBioMedicine. 16:195–203. 2017.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Alimperti S and Andreadis ST: CDH2 and
CDH11 act as regulators of stem cell fate decisions. Stem Cell Res.
14:270–282. 2015.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Kolkova K, Novitskaya V, Pedersen N,
Berezin V and Bock E: Neural cell adhesion molecule-stimulated
neurite outgrowth depends on activation of protein kinase C and the
Ras-mitogen-activated protein kinase pathway. J Neurosci.
15:2238–2246. 2000.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Schmitt KR, Boato F, Diestel A, Hechler D,
Kruglov A, Berger F and Hendrix S: Hypothermia-induced neurite
outgrowth is mediated by tumor necrosis factor-alpha. Brain Pathol.
20:771–779. 2010.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Wang D and Zhang J: Effects of hypothermia
combined with neural stem cell transplantation on recovery of
neurological function in rats with spinal cord injury. Mol Med Rep.
11:1759–1767. 2015.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Radoszkiewicz K, Jezierska-Woźniak K,
Waśniewski T and Sarnowska A: Understanding intra- and
inter-species variability in neural stem cells' biology is key to
their successful cryopreservation, culture, and propagation. Cells.
12:488–499. 2023.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Breschi A, Gingeras TR and Guigó R:
Comparative transcriptomics in human and mouse. Nat Rev Genet.
18:425–440. 2017.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Murray A, Gough G, Cindrić A, Vučković F,
Koschut D, Borelli V, Petrović DJ, Bekavac A, Plećaš A, Hribljan V,
et al: Dose imbalance of DYRK1A kinase causes systemic progeroid
status in Down syndrome by increasing the un-repaired DNA damage
and reducing LaminB1 levels. EBioMedicine.
2023(104692)2023.PubMed/NCBI View Article : Google Scholar
|
![(A and B) Immunohistochemical staining
of neural stem cells in three stages of differentiation: Days 1, 7
and 14, exposed to a normal temperature (37˚C; indicated by ‘N’)
and to hypothermia (32˚C; indicated by ‘H’). The panels on the left
represent DAPI, while those in the middle represent (A) Nestin and
(B) Map2. The panels on the right represent the merged image. It is
visible that on day 1, Nestin is strongly expressed in both
normothermic and hypothermic conditions. On day 7, the Nestin
signal is weaker, but hypothermia does not influence it in any
notable manner. The most notable finding can be seen on day 14
[compare D14N and D14H in (A)]: While in normal conditions Nestin
was almost completely absent, hypothermia re-established the
expression of Nestin. The opposite is visible with the expression
of Map2, which is reduced in hypothermia on day 14 [compare D14N
and D14H in (B)]. Scale bars, 100 µm.](/article_images/mi/5/5/mi-05-05-00252-g02.jpg)
