Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Medicine International
Join Editorial Board Propose a Special Issue
Print ISSN: 2754-3242 Online ISSN: 2754-1304
Journal Cover
May-June 2026 Volume 6 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-June 2026 Volume 6 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report

  • Authors:
    • Saime Paydas
    • Alpay Turan Sezgin
  • View Affiliations / Copyright

    Affiliations: Department of Internal Medicine Nephrology, Acibadem Hospital Döşeme, Adana 01130, Turkey, Department of Cardiology, Acibadem Hospital Döşeme, Adana 01130, Turkey
    Copyright: © Paydas et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 32
    |
    Published online on: April 16, 2026
       https://doi.org/10.3892/mi.2026.316
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:


Abstract

The present case report describes the case of a 76‑year‑old diabetic female patient operated on for ischemic heart disease and aortic valve stenosis. The patient suffered from acute kidney injury related to hypotension secondary to the use of anti‑hypertensive drugs. The present case report also discusses the need for greater caution in treating hypertension in elderly patients with diabetes and cardiovascular disease, drawing on the available literature. Patients should be encouraged to measure their blood pressure at home, and written blood pressure target values should be provided to both the patient and their caregivers. It is important to note that hypotension, similar to hypertension, may lead to complications such as falls, acute kidney injury and hospitalization. Furthermore, the adverse events that develop following simultaneous coronary artery bypass graft and surgical aortic valve replacement surgery in the elderly are discussed in an aim to provide further insight on this matter.
View Figures

Figure 1

Bilateral pleural fluid, cardiomegaly
and metallic suture and clip secondary to coronary artery bypass
graft and surgical aortic valve replacement were determined in the
chest X-ray.

Figure 2

Lower sections of the thoracic
computed tomography scan revealed no abnormalities in the renal
parenchyma and collecting system.
View References

1 

Bahat G, Ribeiro H, Sheppard JP, Bogaerts JMK, Camafort M, Dallmeier D, De Backer T, Desideri G, Olszanecka A, Persu A, et al: Twelve hot questions in the management of hypertension in patients aged 80+ years and their answers with the help of the 2023 European Society of Hypertension Guidelines. J Hypertens. 42:1837–1847. 2024.PubMed/NCBI View Article : Google Scholar

2 

SCORE2-OP working group and ESC Cardiovascular risk collaboration. SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions. Eur Heart J. 42:2455–2467. 2021.PubMed/NCBI View Article : Google Scholar

3 

Hohl CM, Dankoff J, Colacone A and Afilalo M: Polypharmacy, adverse drugrelated events, and potential adverse drug interactions in elderly patients presenting to an emergency department. Ann Emerg Med. 38:666–671. 2001.PubMed/NCBI View Article : Google Scholar

4 

Bourgeois FT, Shannon MW, Valim C and Mandl KD: Adverse drug events in the outpatient setting: An 11-year national analysis. Pharmacoepidemiol Drug Saf. 19:901–910. 2010.PubMed/NCBI View Article : Google Scholar

5 

Writing Committee Members*. Jones DW, Ferdinand KC, Taler SJ, Johnson HM, Shimbo D, Abdalla M, Altieri MM, Bansa N, Bello NA, Bress AP, et al: 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Hypertension. 82:e212–e316. 2025.PubMed/NCBI View Article : Google Scholar

6 

Pavasini R, Biscaglia S, Kunadian V, Hakeem A and Campo G: Coronary artery disease management in older adults: Revascularization and exercise training. Eur Heart J. 45:2811–2823. 2024.PubMed/NCBI View Article : Google Scholar

7 

Lin YW, Wang Q, Lu PS, Jiang M, Li XH, Wang SH, Liao X, Zeng QC, Yu DQ and Wei XB: Early acute kidney injury recovery in elderly patients undergoing valve replacement surgery. J Cardiothorac Vasc Anesth. 38:2261–2268. 2024.PubMed/NCBI View Article : Google Scholar

8 

KDIGO: KDIGO Clinical Practice Guideline for Acute Kidney Injury (AKI) and Acute Kidney Disease (AKD)/ Update 2023. https://kdigo.org › wp-content › uploads › 2023/10.

9 

Piątek J, Kędziora A, Kiełbasa G, Olszewska M, Sobczyk D, Song BH, Konstanty-Kalandyk J, Darocha T, Wierzbicki K, Milaniak I, et al: How to predict the risk of postoperative complications after coronary artery bypass grafting in patients under 50 and over 80 years old. A retrospective cross-sectional study. Kardiol Pol. 75:975–982. 2017.PubMed/NCBI View Article : Google Scholar

10 

Bobet AS, Brouessard C, Le Tourneau T, Manigold T, de Decker L and Boureau AS: Length of stay in older patients undergoing transcatheter aortic valve replacement: Value of a geriatric approach. Gerontology. 68:746–754. 2022.PubMed/NCBI View Article : Google Scholar

11 

Wang X, Zhang C, Pan MM, Lin HW, Xue S, Xie B and Gu ZC: Design and rationale of the multicenter randomized clinical trial (REVERSE): Efficacy and safety of rivaroxaban in the early postoperative period for patients with bioprosthetic valve replacement or valve repair. Int J Cardiol. 425(133023)2025.PubMed/NCBI View Article : Google Scholar

12 

Yang L, Wu ZJ, Weng H, Wu D, Lu JQ and Chen SL: The prognostic value of estimated glomerular filtration rate change in elderly patients undergoing valvular replacement surgery. Arch Gerontol Geriatr. 130(105719)2025.PubMed/NCBI View Article : Google Scholar

13 

Witberg G, Steinmetz T, Landes U, Pistiner Hanit R, Green H, Goldman S, Vaknin-Assa H, Codner P, Perl L, Rozen-Zvi B and Kornowski R: Change in kidney function and 2-year mortality after transcatheter aortic valve replacement. JAMA Netw Open. 4(e213296)2021.PubMed/NCBI View Article : Google Scholar

14 

Gatta F, Haqzad Y, Gradinariu G, Malvindi PG, Khalid Z, Suelo-Calanao RL, Moawad N, Bashir A, Rogers LJ, Lloyd C, et al: Redo aortic valve replacement versus valve-in-valve trans-catheter aortic valve implantation: A UK propensity-matched analysis. Monaldi Arch Chest Dis. 94(1):2023.PubMed/NCBI View Article : Google Scholar

15 

Andrási TB, Schellenberg C, Vasiloi A and Glück AC: Health-related quality of life after minimal-invasive treatment of aortic valve stenosis in the elderly. J Thorac Dis. 16:2274–2284. 2024.PubMed/NCBI View Article : Google Scholar

16 

Khan MZ, Khan MU, Kalra A, Krupica T, Kaluski E and Khan SU: Transcatheter versus surgical aortic valve replacement in patients with end stage renal disease. Catheter Cardiovasc Interv. 96:1102–1109. 2020.PubMed/NCBI View Article : Google Scholar

17 

Mubashir T, Balogh J, Chaudhry R, Quiroz C, Kar B, De Armas IAS, Liang Y, Markham T, Kumar R, Choi W, et al: Transcatheter and surgical aortic valve replacement outcomes for patients with chronic heart failure. J Cardiothorac Vasc Anesth. 35:888–895. 2021.PubMed/NCBI View Article : Google Scholar

18 

Lu R, Dismorr M, Hertzberg D, Glaser N and Sartipy U: Early creatinine changes after aortic valve replacement and late survival, heart failure, and chronic kidney disease in a national registry. Ann Thorac Surg. 119:577–584. 2025.PubMed/NCBI View Article : Google Scholar

19 

Mourad F, Haddad A, Nowak J, Elbarraki M, Elhmidi Y, Jasarevic M, Marx P, Demircioglu E, Wendt D, Thielmann M, et al: Impact of non-valvular non-coronary concomitant procedures on outcomes of surgical aortic valve replacement in intermediate risk patients. J Clin Med. 10(5592)2021.PubMed/NCBI View Article : Google Scholar

20 

D'Alessandro S, Tuttolomondo D, Singh G, Hernandez-Vaquero D, Pattuzzi C, Gallingani A, Maestri F, Nicolini F and Formica F: The early and long-term outcomes of coronary artery bypass grafting added to aortic valve replacement compared to isolated aortic valve replacement in elderly patients: A systematic review and meta-analysis. Heart Vessels. 37:1647–1661. 2022.PubMed/NCBI View Article : Google Scholar

21 

Taleb Bendiab T, Brusset A, Estagnasié P, Squara P and Nguyen LS: Performance of EuroSCORE II and Society of Thoracic Surgeons risk scores in elderly patients undergoing aortic valve replacement surgery. Arch Cardiovasc Dis. 114:474–481. 2021.PubMed/NCBI View Article : Google Scholar

22 

Florian A, Auer J, Reichardt B, Krotka P, Wagenlechner C, Wendt R, Mildner M, Mascherbauer J, Ankersmit HJ, Zimpfer D and Graf A: The choice of surgical aortic valve replacement type and mid-term outcomes in 50 to 65-year-olds: results of the AUTHEARTVISIT study. Eur J Cardiothorac Surg. 67(ezaf200)2025.PubMed/NCBI View Article : Google Scholar

23 

Bangalore S, Rhodes G, Maron DJ, Anthopolos R, O'Brien SM, Jones PG, Mark DB, Reynolds HR, Spertus JA, Stone GW, et al: Outcomes with revascularisation versus conservative management of participants with 3-vessel coronary artery disease in the ISCHEMIA trial. EuroIntervention. 20:e1276–e1287. 2024.PubMed/NCBI View Article : Google Scholar

24 

Lin S, Zhao R, Zhang H, Liang Y, Lin J, Yu M, Li D, Zhang B, Ma L and Peng L: Assessing the risk of acute kidney injury associated with a four-drug regimen for heart failure: A ten-year real-world pharmacovigilance analysis based on FAERS events. Expert Opin Drug Saf. 24:547–556. 2025.PubMed/NCBI View Article : Google Scholar

25 

Villain C, Metzger M, Liabeuf S, Hamroun A, Laville S, Mansencal N, Combe C, Fouque D, Frimat L, Jacquelinet C, et al: Effectiveness and tolerance of renin-angiotensin system inhibitors with aging in chronic kidney disease. J Am Med Dir Assoc. 23:998–1004. e7. 2022.PubMed/NCBI View Article : Google Scholar

26 

Sheppard JP, Koshiaris C, Stevens R, Lay-Flurrie S, Banerjee A, Bellows BK, Clegg A, Hobbs FDR, Payne RA, Swain S, et al: The association between antihypertensive treatment and serious adverse events by age and frailty: A cohort study. PLoS Med. 20(e1004223)2023.PubMed/NCBI View Article : Google Scholar

27 

D'Anci KE, Tipton K, Hedden-Gross A, Rouse B, Hermanson L and Fontanarosa J: Effect of intensive blood pressure lowering on cardiovascular outcomes: A systematic review prepared for the 2020. U.S. Department of veterans affairs/U.S. department of defense guidelines. Ann Intern Med. 173:895–903. 2020.PubMed/NCBI View Article : Google Scholar

28 

Angeli F, Reboldi G and Verdecchia P: Blood pressure goal for hypertension in the elderly. G Ital Cardiol (Rome). 24:305–309. 2023.PubMed/NCBI View Article : Google Scholar : (In Italian).

29 

Perschinka F, Boyer N, Forni LG and Joannidis M: Renal function in very old critically ill patients. Curr Opin Crit Care. 29:534–541. 2023.PubMed/NCBI View Article : Google Scholar

30 

Ballas C, Katsouras CS, Tourmousoglou C, Siaravas KC, Tzourtzos I and Alexiou C: A review on the etiologies of the development of atrial fibrillation after cardiac surgery. Biomolecules. 15(374)2025.PubMed/NCBI View Article : Google Scholar

31 

Zhou JY, Zhang JL, Xi L, Guo ZP, Liu XC, Liu ZG, Yang Q and He GW: Risk factors of postoperative atrial fibrillation after isolated coronary artery bypass grafting surgery in the recent 10 years: Clinical analysis of 6229 patients. Clin Cardiol. 47(e24335)2024.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
Copy and paste a formatted citation
Spandidos Publications style
Paydas S and Sezgin AT: Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report. Med Int 6: 32, 2026.
APA
Paydas, S., & Sezgin, A.T. (2026). Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report. Medicine International, 6, 32. https://doi.org/10.3892/mi.2026.316
MLA
Paydas, S., Sezgin, A. T."Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report". Medicine International 6.3 (2026): 32.
Chicago
Paydas, S., Sezgin, A. T."Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report". Medicine International 6, no. 3 (2026): 32. https://doi.org/10.3892/mi.2026.316
Copy and paste a formatted citation
x
Spandidos Publications style
Paydas S and Sezgin AT: Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report. Med Int 6: 32, 2026.
APA
Paydas, S., & Sezgin, A.T. (2026). Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report. Medicine International, 6, 32. https://doi.org/10.3892/mi.2026.316
MLA
Paydas, S., Sezgin, A. T."Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report". Medicine International 6.3 (2026): 32.
Chicago
Paydas, S., Sezgin, A. T."Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report". Medicine International 6, no. 3 (2026): 32. https://doi.org/10.3892/mi.2026.316
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team