Association between γ-glutamyltransferase and prehypertension

  • Authors:
    • Xuzhen Qin
    • Guodong Tang
    • Ling Qiu
    • Tao Xu
    • Xinqi Cheng
    • Shaomei Han
    • Guangjin Zhu
    • Yajun Liu
  • View Affiliations

  • Published online on: January 20, 2012     https://doi.org/10.3892/mmr.2012.761
  • Pages: 1092-1098
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Abstract

Researchers have identified an association between baseline γ-glutamyltransferase (GGT) and prehypertension. However, data from China are limited. A cross-sectional study was performed among 2,205 subjects from Heilongjiang Province in China. Multiple logistic regression analyses revealed a significant association between baseline GGT and prehypertension [1.59, 95% confidence interval (CI), 1.18‑2.16], comparing quartile 4 to quartile 1. Subgroup analyses showed a stronger association between GGT and prehypertension in Koreans; men, current alcohol drinkers and subjects with pre‑diabetes. Receiver operating characteristics (ROC) analysis demonstrated that when GGT was higher than 20 U/l, the risk of developing prehypertension increased. Serum GGT is used as a biochemical liver test, but our findings suggest that baseline values may also predict prehypertension in Chinese.
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April 2012
Volume 5 Issue 4

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Qin X, Tang G, Qiu L, Xu T, Cheng X, Han S, Zhu G and Liu Y: Association between γ-glutamyltransferase and prehypertension. Mol Med Rep 5: 1092-1098, 2012
APA
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S. ... Liu, Y. (2012). Association between γ-glutamyltransferase and prehypertension. Molecular Medicine Reports, 5, 1092-1098. https://doi.org/10.3892/mmr.2012.761
MLA
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S., Zhu, G., Liu, Y."Association between γ-glutamyltransferase and prehypertension". Molecular Medicine Reports 5.4 (2012): 1092-1098.
Chicago
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S., Zhu, G., Liu, Y."Association between γ-glutamyltransferase and prehypertension". Molecular Medicine Reports 5, no. 4 (2012): 1092-1098. https://doi.org/10.3892/mmr.2012.761