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April 2012 Volume 5 Issue 4

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Article

Association between γ-glutamyltransferase and prehypertension

  • Authors:
    • Xuzhen Qin
    • Guodong Tang
    • Ling Qiu
    • Tao Xu
    • Xinqi Cheng
    • Shaomei Han
    • Guangjin Zhu
    • Yajun Liu
  • View Affiliations / Copyright

    Affiliations: Department of Clinical Laboratory, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, P.R. China, Department of Cardiology, Bejing Hospital, Beijing, P.R. China, Institute of Basic Medical Sciences of Chinese Academy of Medical Sciences and School of Basic Medicine of Peking Union Medical College, Beijing, P.R. China, Institute of Microcirculation, Chinese Academy of Medical Sciences and School of Basic Medicine of Peking Union Medical College, Beijing, P.R. China
  • Pages: 1092-1098
    |
    Published online on: January 20, 2012
       https://doi.org/10.3892/mmr.2012.761
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Abstract

Researchers have identified an association between baseline γ-glutamyltransferase (GGT) and prehypertension. However, data from China are limited. A cross-sectional study was performed among 2,205 subjects from Heilongjiang Province in China. Multiple logistic regression analyses revealed a significant association between baseline GGT and prehypertension [1.59, 95% confidence interval (CI), 1.18‑2.16], comparing quartile 4 to quartile 1. Subgroup analyses showed a stronger association between GGT and prehypertension in Koreans; men, current alcohol drinkers and subjects with pre‑diabetes. Receiver operating characteristics (ROC) analysis demonstrated that when GGT was higher than 20 U/l, the risk of developing prehypertension increased. Serum GGT is used as a biochemical liver test, but our findings suggest that baseline values may also predict prehypertension in Chinese.
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Copy and paste a formatted citation
Spandidos Publications style
Qin X, Tang G, Qiu L, Xu T, Cheng X, Han S, Zhu G and Liu Y: Association between γ-glutamyltransferase and prehypertension. Mol Med Rep 5: 1092-1098, 2012.
APA
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S. ... Liu, Y. (2012). Association between γ-glutamyltransferase and prehypertension. Molecular Medicine Reports, 5, 1092-1098. https://doi.org/10.3892/mmr.2012.761
MLA
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S., Zhu, G., Liu, Y."Association between γ-glutamyltransferase and prehypertension". Molecular Medicine Reports 5.4 (2012): 1092-1098.
Chicago
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S., Zhu, G., Liu, Y."Association between γ-glutamyltransferase and prehypertension". Molecular Medicine Reports 5, no. 4 (2012): 1092-1098. https://doi.org/10.3892/mmr.2012.761
Copy and paste a formatted citation
x
Spandidos Publications style
Qin X, Tang G, Qiu L, Xu T, Cheng X, Han S, Zhu G and Liu Y: Association between γ-glutamyltransferase and prehypertension. Mol Med Rep 5: 1092-1098, 2012.
APA
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S. ... Liu, Y. (2012). Association between γ-glutamyltransferase and prehypertension. Molecular Medicine Reports, 5, 1092-1098. https://doi.org/10.3892/mmr.2012.761
MLA
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S., Zhu, G., Liu, Y."Association between γ-glutamyltransferase and prehypertension". Molecular Medicine Reports 5.4 (2012): 1092-1098.
Chicago
Qin, X., Tang, G., Qiu, L., Xu, T., Cheng, X., Han, S., Zhu, G., Liu, Y."Association between γ-glutamyltransferase and prehypertension". Molecular Medicine Reports 5, no. 4 (2012): 1092-1098. https://doi.org/10.3892/mmr.2012.761
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