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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2012 Volume 5 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

DNA methylation in the human placenta and fetal growth (Review)

Ourania Koukoura, Stavros Sifakis, Demetrios A. Spandidos
Pages: 883-889
Published online on: 24 January 2012

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Review

microRNAs as tumor inhibitors, oncogenes, biomarkers for drug efficacy and outcome predictors in lung cancer (Review)

Yan-Wen Jiang, Liang-An Chen
Pages: 890-894
Published online on: 03 February 2012

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Review

Role of liver X receptors in cholesterol efflux and inflammatory signaling (Review)

Rongtao Zhu, Zhibing Ou, Xiongzhong Ruan, Jianping Gong
Pages: 895-900
Published online on: 17 January 2012

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Article

Evaluation of HOXB13 as a molecular marker of recurrent prostate cancer

Tae-O Jeong, Kyung-Jin Oh, Nguyen Thi Xuan Nguyen, Young-Rang Kim, Min Soo Kim, Sang Don Lee, Soo Bang Ryu, Chaeyong Jung
Pages: 901-904
Published online on: 30 January 2012

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Article

γ-tocotrienol attenuates TNF-α-induced changes in secretion and gene expression of MCP-1, IL-6 and adiponectin in 3T3-L1 adipocytes

Tetsuro Matsunaga, Ayae Shoji, Ning Gu, Erina Joo, Shiho Li, Tetsuya Adachi, Hanae Yamazaki, Koichiro Yasuda, Takashi Kondoh, Kinsuke Tsuda
Pages: 905-909
Published online on: 30 January 2012

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Article

Expression of immunoglobulin-like transcript (ILT)2 and ILT3 in human gastric cancer and its clinical significance

Yi Zhang, Nan Lu, Yuwen Xue, Min Zhang, Yingjie Li, Yuanquan Si, Xiaokun Bian, Yanfei Jia, Yunshan Wang
Pages: 910-916
Published online on: 09 January 2012

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Article

Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells

Xiang-Qi Chen, Sheng Yang, Zhi-Ying Li, Hui-Shan Lu, Ming-Qiang Kang, Ting-Yan Lin
Pages: 917-922
Published online on: 13 January 2012

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Article

Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats

Jinglong Huang, Dongming Wang, Jinbin Zheng, Xiansheng Huang, Hong Jin
Pages: 923-928
Published online on: 09 January 2012

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Article

Mitochondria-targeted antioxidant attenuates high glucose-induced P38 MAPK pathway activation in human neuroblastoma cells

Mingfeng Cao, Jinjiao Jiang, Yifeng Du, Peng Yan
Pages: 929-934
Published online on: 09 January 2012

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Article

P-selectin-mediated platelet activation promotes adhesion of non-small cell lung carcinoma cells on vascular endothelial cells under flow

Liang Gong, Hong-Jian Mi, Hongchu Zhu, Xiangdong Zhou, Heping Yang
Pages: 935-942
Published online on: 19 January 2012

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Article

Mutation spectrum of the TYR and SLC45A2 genes in patients with oculocutaneous albinism

Jung Min Ko, Jung-Ah Yang, Seon-Yong Jeong, Hyon-Ju Kim
Pages: 943-948
Published online on: 25 January 2012

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Article

microRNA-155 silencing inhibits proliferation and migration and induces apoptosis by upregulating BACH1 in renal cancer cells

Songchao Li, Tieding Chen, Zhaohui Zhong, Yi Wang, Yangle Li, Xiaokun Zhao
Pages: 949-954
Published online on: 03 February 2012

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Article

Effect of radiation on the expression of osteoclast marker genes in RAW264.7 cells

Bing Yang, Hui Zhou, Xiao-Dong Zhang, Zheng Liu, Fei-Yue Fan, Yuan-Ming Sun
Pages: 955-958
Published online on: 25 January 2012

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Article

Lymphangiogenesis and biological behavior in pancreatic carcinoma and other pancreatic tumors

Zhongqiu Wang, Jiang Wu, Guojun Li, Xinhua Zhang, Mingmin Tong, Zhengcan Wu, Zhenjuan Liu
Pages: 959-963
Published online on: 09 January 2012

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Article

Augmentation of transgenic expression by ultrasound‑mediated liposome microbubble destruction

Zhi-Yi Chen, Xiao-Fang Sun, Jian-Qiao Liu, Bing Si-Tu, Ri-Xiang Qiu, Kun Liang, Jian-Hua Liu, Wei-Xiang Liang, Xin-Xin Zhou, Hua Zhang, Jiang-Xiu Yu
Pages: 964-970
Published online on: 25 January 2012

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Case Report

Simultaneous squamous cell carcinoma with primary malignant fibrous histiocytoma of the larynx: A case report

Xiaolin Cao, Jun Liu, Youyang Zheng, Qiaoyun Li, Yaoshu Teng, Yong Li
Pages: 971-973
Published online on: 01 February 2012

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Article

AlloDerm implants for prevention of Frey syndrome after parotidectomy: A systematic review and meta-analysis

Xian-Tao Zeng, Xiang-Jun Tang, Xue-Jun Wang, Miao-Zhu Li, Yi Guo, Wei Huang, Yu-Ming Niu, Wei-Dong Leng
Pages: 974-980
Published online on: 20 January 2012

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Article

Intense picosecond pulsed electric fields induce apoptosis through a mitochondrial-mediated pathway in HeLa cells

Yuan-Yuan Hua, Xiao-Shu Wang, Yu Zhang, Chen-Guo Yao, Xi-Ming Zhang, Zheng-Ai Xiong
Pages: 981-987
Published online on: 03 February 2012

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Article

Mouse forestomach carcinoma cells immunosuppress macrophages through transforming growth factor-β1

Huaxing Luo, Yingxue Hao, Bo Tang, Dongzhu Zeng, Yan Shi, Peiwu Yu
Pages: 988-992
Published online on: 03 February 2012

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Article

Subproteomic analysis of basic proteins in aged skeletal muscle following offgel pre-fractionation

Joan Gannon, Kay Ohlendieck
Pages: 993-1000
Published online on: 17 January 2012

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Article

Detection of human enterovirus 71 and coxsackievirus A16 in children with hand, foot and mouth disease in China

Ling Chen, Xiaozhou Mou, Qiong Zhang, Yifei Li, Jian Lin, Fanlong Liu, Li Yuan, Yiming Tang, Charlie Xiang
Pages: 1001-1004
Published online on: 03 January 2012

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Article

Lipopolysaccharide and dose of nicotine determine the effects of nicotine on murine bone marrow-derived dendritic cells

Su Xian Hu, Hua Xiu Sui, Hao Jie Jin, Xiao Yan Ni, Xiao Xing Liu, Mao Qiang Xue, Ye Zhang, Feng Guang Gao
Pages: 1005-1010
Published online on: 12 January 2012

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Article

Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

Evanthia Kousi, Ioannis Tsougos, Konstantinos Fountas, Kiriaki Theodorou, Evaggelia Tsolaki, Ioannis Fezoulidis, Eftichia Kapsalaki
Pages: 1011-1018
Published online on: 30 January 2012

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Article

Tanshinone IIA inhibits human breast cancer MDA-MB-231 cells by decreasing LC3-II, Erb-B2 and NF-κBp65

Chin-Cheng Su, Su-Yu Chien, Shou-Jen Kuo, Yao-Li Chen, Chun-Yuan Cheng, Dar-Ren Chen
Pages: 1019-1022
Published online on: 13 January 2012

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Article

Effects of the pro-inflammatory milieu on the dedifferentiation of cultured fibroblast-like synoviocytes

Hong Seo Choi, Chun Jeih Ryu, Hyun Mi Choi, Jin Sung Park, Jae-Hoon Lee, Kang Il Kim, Hyung-In Yang, Myung Chul Yoo, Kyoung Soo Kim
Pages: 1023-1026
Published online on: 25 January 2012

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Article

Ethanol-induced DNA damage and repair-related molecules in human intestinal epithelial Caco-2 cells

Sung Chul Park, Ji-Youn Lim, Yoon Tae Jeen, Bora Keum, Yeon Seok  Seo, Yong Sik Kim, Sung Joon Lee, Hong Sik Lee, Hoon Jai Chun, Soon Ho  Um, Chang Duck Kim, Ho Sang Ryu, Donggeun Sul, Eunha Oh
Pages: 1027-1032
Published online on: 12 January 2012

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Article

Expression of WNT-5a and ROR2 correlates with disease severity in osteosarcoma

Bei-Ji Lu, Yun-Qing Wang, Xue-Jie Wei, Liang-Qun Rong, Dong Wei, Chang-Ming Yan, Deng-Jie Wang, Jun-Ying Sun
Pages: 1033-1036
Published online on: 30 January 2012

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Article

Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells

A. Çoker, E. D. Arısan, N. Palavan-Ünsal
Pages: 1037-1042
Published online on: 30 January 2012

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Article

Computational analysis of novel drugs designed for use as acetylcholinesterase inhibitors and histamine H3 receptor antagonists for Alzheimer's disease by docking, scoring and de novo evolution

Po-Yuan Chen, Ching-Tsan Tsai, Che-Yen Ou, Wei-Tse Hsu, Mien-De Jhuo, Chieh-Hsi Wu, Tzu-Ching Shih, Tzu-Hurng Cheng, Jing-Gung Chung
Pages: 1043-1048
Published online on: 17 January 2012

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Article

TRESK gene recombinant adenovirus vector inhibits capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons

Jun Zhou, Shang-Long Yao, Cheng-Xiang Yang, Ji-Ying Zhong, Han-Bing Wang, Yan Zhang
Pages: 1049-1052
Published online on: 03 February 2012

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Article

The blues of P(16)INK(4a): Aberrant promoter methylation and association with colorectal cancer in the Kashmir valley

A. Syed Sameer, Safiya Abdullah, Saniya Nissar, Roohi Rasool, Zaffar A. Shah, Dil Afroze, Nissar A. Chowdri, Mushtaq A. Siddiqi
Pages: 1053-1057
Published online on: 03 January 2012

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Article

Polymorphisms in the 3'UTR of the human leptin gene and their role in hypertension

Qulsum Akhter, Akbar Masood, Ruhi Ashraf, Sabia Majid, Sabah Rasool, Tanzeela Khan, Tabasum Rashid, A. Syed Sameer, Bashir Ahmad Ganai
Pages: 1058-1062
Published online on: 04 January 2012

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Article

The JAK2-Akt-glycogen synthase kinase-3β signaling pathway is involved in toll-like receptor 2-induced monocyte chemoattractant protein-1 regulation

Dae-Weon Park, Hyung-Kyoung Lee, Tae-Whal Jeong, Jin-Sik Kim, Yoe-Sik Bae, Byung-Rho Chin, Suk-Hwan Baek
Pages: 1063-1067
Published online on: 03 January 2012

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Article

Effect of metformin on the proliferation, migration, and MMP-2 and -9 expression of human umbilical vein endothelial cells

Nilufar Esfahanian, Yadollah Shakiba, Behroz Nikbin, Hamid Soraya, Nasrin Maleki-Dizaji, Mahmood Ghazi-Khansari, Alireza Garjani
Pages: 1068-1074
Published online on: 12 January 2012

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Article

Downregulation of Id1 by small interfering RNA in gastric cancer inhibits cell growth via the Akt pathway

Guang Yang, Yan Zhang, Jianjun Xiong, Jing Wu, Changfu Yang, Hongbing Huang, Zhenyu Zhu
Pages: 1075-1079
Published online on: 12 January 2012

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Article

Changes in T lymphocyte subsets and intracellular cytokines after transfer of chemically extracted acellular nerve allografts

Wei Li, Wen-Wen Wu, Xing-Shi Lin, Shu-Xun Hou, Hong-Bin Zhong, Di-Ke Ruan
Pages: 1080-1086
Published online on: 09 January 2012

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Article

Correlation between hammerhead ribozyme-mediated eggshell protein gene cleavage and reproduction inhibition of Schistosoma japonicum

Yu Liang, Yuelan Zhou, Weiguo Yin, Yingju Li, Qiulin Yang, Yuan Gao, Yukuai Zhang, Yaofei Yang, Li Peng, Jianhua Xiao
Pages: 1087-1091
Published online on: 12 January 2012

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Article

Association between γ-glutamyltransferase and prehypertension

Xuzhen Qin, Guodong Tang, Ling Qiu, Tao Xu, Xinqi Cheng, Shaomei Han, Guangjin Zhu, Yajun Liu
Pages: 1092-1098
Published online on: 20 January 2012

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Article

Steroid receptor coactivator-3 differentially regulates the inflammatory response in peritoneal macrophages

Jun Li, Ying-Hai Liu, Shan Ou, Xue-Mei Dai, Jun-Ping Wang, Yong-Ping Su
Pages: 1099-1105
Published online on: 12 January 2012

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Article

Reduced levels of p15INK4b, p16INK4a, p21cip1 and p27kip1 in pancreatic carcinoma

Gang Li, Yuan Ji, Chen Liu, JingQi Li, YingQi Zhou
Pages: 1106-1110
Published online on: 30 January 2012

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Article

The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's disease

Erik Portelius, Juan Fortea, Jose Luis Molinuevo, Mikael K. Gustavsson, Ulf Andreasson, Raquel Sanchez-Valle
Pages: 1111-1115
Published online on: 01 February 2012

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Article

Aldehyde dehydrogenase activity is a cancer stem cell marker of tongue squamous cell carcinoma

Bo Zou, Shoujuan Sun, Xiaojuan Qi, Ping Ji
Pages: 1116-1120
Published online on: 03 February 2012

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Article

Defective activities, but not secretions, resulting from gene point mutations of human mannan-binding lectin

Ying Liu, Feng-Ling Liu, Zhi-Jun Bai, Na Zhao, Li-Yun Zhang, Xiao Lu, Zheng-Liang Chen
Pages: 1121-1127
Published online on: 06 February 2012

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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March-2026 Volume 33 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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