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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2012 Volume 5 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

DNA methylation in the human placenta and fetal growth (Review)

Ourania Koukoura, Stavros Sifakis, Demetrios A. Spandidos
Pages: 883-889
Published online on: 24 January 2012

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Review

microRNAs as tumor inhibitors, oncogenes, biomarkers for drug efficacy and outcome predictors in lung cancer (Review)

Yan-Wen Jiang, Liang-An Chen
Pages: 890-894
Published online on: 03 February 2012

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Review

Role of liver X receptors in cholesterol efflux and inflammatory signaling (Review)

Rongtao Zhu, Zhibing Ou, Xiongzhong Ruan, Jianping Gong
Pages: 895-900
Published online on: 17 January 2012

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Article

Evaluation of HOXB13 as a molecular marker of recurrent prostate cancer

Tae-O Jeong, Kyung-Jin Oh, Nguyen Thi Xuan Nguyen, Young-Rang Kim, Min Soo Kim, Sang Don Lee, Soo Bang Ryu, Chaeyong Jung
Pages: 901-904
Published online on: 30 January 2012

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Article

γ-tocotrienol attenuates TNF-α-induced changes in secretion and gene expression of MCP-1, IL-6 and adiponectin in 3T3-L1 adipocytes

Tetsuro Matsunaga, Ayae Shoji, Ning Gu, Erina Joo, Shiho Li, Tetsuya Adachi, Hanae Yamazaki, Koichiro Yasuda, Takashi Kondoh, Kinsuke Tsuda
Pages: 905-909
Published online on: 30 January 2012

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Article

Expression of immunoglobulin-like transcript (ILT)2 and ILT3 in human gastric cancer and its clinical significance

Yi Zhang, Nan Lu, Yuwen Xue, Min Zhang, Yingjie Li, Yuanquan Si, Xiaokun Bian, Yanfei Jia, Yunshan Wang
Pages: 910-916
Published online on: 09 January 2012

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Article

Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells

Xiang-Qi Chen, Sheng Yang, Zhi-Ying Li, Hui-Shan Lu, Ming-Qiang Kang, Ting-Yan Lin
Pages: 917-922
Published online on: 13 January 2012

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Article

Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats

Jinglong Huang, Dongming Wang, Jinbin Zheng, Xiansheng Huang, Hong Jin
Pages: 923-928
Published online on: 09 January 2012

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Article

Mitochondria-targeted antioxidant attenuates high glucose-induced P38 MAPK pathway activation in human neuroblastoma cells

Mingfeng Cao, Jinjiao Jiang, Yifeng Du, Peng Yan
Pages: 929-934
Published online on: 09 January 2012

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Article

P-selectin-mediated platelet activation promotes adhesion of non-small cell lung carcinoma cells on vascular endothelial cells under flow

Liang Gong, Hong-Jian Mi, Hongchu Zhu, Xiangdong Zhou, Heping Yang
Pages: 935-942
Published online on: 19 January 2012

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Article

Mutation spectrum of the TYR and SLC45A2 genes in patients with oculocutaneous albinism

Jung Min Ko, Jung-Ah Yang, Seon-Yong Jeong, Hyon-Ju Kim
Pages: 943-948
Published online on: 25 January 2012

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Article

microRNA-155 silencing inhibits proliferation and migration and induces apoptosis by upregulating BACH1 in renal cancer cells

Songchao Li, Tieding Chen, Zhaohui Zhong, Yi Wang, Yangle Li, Xiaokun Zhao
Pages: 949-954
Published online on: 03 February 2012

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Article

Effect of radiation on the expression of osteoclast marker genes in RAW264.7 cells

Bing Yang, Hui Zhou, Xiao-Dong Zhang, Zheng Liu, Fei-Yue Fan, Yuan-Ming Sun
Pages: 955-958
Published online on: 25 January 2012

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Article

Lymphangiogenesis and biological behavior in pancreatic carcinoma and other pancreatic tumors

Zhongqiu Wang, Jiang Wu, Guojun Li, Xinhua Zhang, Mingmin Tong, Zhengcan Wu, Zhenjuan Liu
Pages: 959-963
Published online on: 09 January 2012

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Article

Augmentation of transgenic expression by ultrasound‑mediated liposome microbubble destruction

Zhi-Yi Chen, Xiao-Fang Sun, Jian-Qiao Liu, Bing Si-Tu, Ri-Xiang Qiu, Kun Liang, Jian-Hua Liu, Wei-Xiang Liang, Xin-Xin Zhou, Hua Zhang, Jiang-Xiu Yu
Pages: 964-970
Published online on: 25 January 2012

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Case Report

Simultaneous squamous cell carcinoma with primary malignant fibrous histiocytoma of the larynx: A case report

Xiaolin Cao, Jun Liu, Youyang Zheng, Qiaoyun Li, Yaoshu Teng, Yong Li
Pages: 971-973
Published online on: 01 February 2012

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Article

AlloDerm implants for prevention of Frey syndrome after parotidectomy: A systematic review and meta-analysis

Xian-Tao Zeng, Xiang-Jun Tang, Xue-Jun Wang, Miao-Zhu Li, Yi Guo, Wei Huang, Yu-Ming Niu, Wei-Dong Leng
Pages: 974-980
Published online on: 20 January 2012

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Article

Intense picosecond pulsed electric fields induce apoptosis through a mitochondrial-mediated pathway in HeLa cells

Yuan-Yuan Hua, Xiao-Shu Wang, Yu Zhang, Chen-Guo Yao, Xi-Ming Zhang, Zheng-Ai Xiong
Pages: 981-987
Published online on: 03 February 2012

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Article

Mouse forestomach carcinoma cells immunosuppress macrophages through transforming growth factor-β1

Huaxing Luo, Yingxue Hao, Bo Tang, Dongzhu Zeng, Yan Shi, Peiwu Yu
Pages: 988-992
Published online on: 03 February 2012

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Article

Subproteomic analysis of basic proteins in aged skeletal muscle following offgel pre-fractionation

Joan Gannon, Kay Ohlendieck
Pages: 993-1000
Published online on: 17 January 2012

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Article

Detection of human enterovirus 71 and coxsackievirus A16 in children with hand, foot and mouth disease in China

Ling Chen, Xiaozhou Mou, Qiong Zhang, Yifei Li, Jian Lin, Fanlong Liu, Li Yuan, Yiming Tang, Charlie Xiang
Pages: 1001-1004
Published online on: 03 January 2012

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Article

Lipopolysaccharide and dose of nicotine determine the effects of nicotine on murine bone marrow-derived dendritic cells

Su Xian Hu, Hua Xiu Sui, Hao Jie Jin, Xiao Yan Ni, Xiao Xing Liu, Mao Qiang Xue, Ye Zhang, Feng Guang Gao
Pages: 1005-1010
Published online on: 12 January 2012

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Article

Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

Evanthia Kousi, Ioannis Tsougos, Konstantinos Fountas, Kiriaki Theodorou, Evaggelia Tsolaki, Ioannis Fezoulidis, Eftichia Kapsalaki
Pages: 1011-1018
Published online on: 30 January 2012

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Article

Tanshinone IIA inhibits human breast cancer MDA-MB-231 cells by decreasing LC3-II, Erb-B2 and NF-κBp65

Chin-Cheng Su, Su-Yu Chien, Shou-Jen Kuo, Yao-Li Chen, Chun-Yuan Cheng, Dar-Ren Chen
Pages: 1019-1022
Published online on: 13 January 2012

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Article

Effects of the pro-inflammatory milieu on the dedifferentiation of cultured fibroblast-like synoviocytes

Hong Seo Choi, Chun Jeih Ryu, Hyun Mi Choi, Jin Sung Park, Jae-Hoon Lee, Kang Il Kim, Hyung-In Yang, Myung Chul Yoo, Kyoung Soo Kim
Pages: 1023-1026
Published online on: 25 January 2012

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Article

Ethanol-induced DNA damage and repair-related molecules in human intestinal epithelial Caco-2 cells

Sung Chul Park, Ji-Youn Lim, Yoon Tae Jeen, Bora Keum, Yeon Seok  Seo, Yong Sik Kim, Sung Joon Lee, Hong Sik Lee, Hoon Jai Chun, Soon Ho  Um, Chang Duck Kim, Ho Sang Ryu, Donggeun Sul, Eunha Oh
Pages: 1027-1032
Published online on: 12 January 2012

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Article

Expression of WNT-5a and ROR2 correlates with disease severity in osteosarcoma

Bei-Ji Lu, Yun-Qing Wang, Xue-Jie Wei, Liang-Qun Rong, Dong Wei, Chang-Ming Yan, Deng-Jie Wang, Jun-Ying Sun
Pages: 1033-1036
Published online on: 30 January 2012

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Article

Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells

A. Çoker, E. D. Arısan, N. Palavan-Ünsal
Pages: 1037-1042
Published online on: 30 January 2012

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Article

Computational analysis of novel drugs designed for use as acetylcholinesterase inhibitors and histamine H3 receptor antagonists for Alzheimer's disease by docking, scoring and de novo evolution

Po-Yuan Chen, Ching-Tsan Tsai, Che-Yen Ou, Wei-Tse Hsu, Mien-De Jhuo, Chieh-Hsi Wu, Tzu-Ching Shih, Tzu-Hurng Cheng, Jing-Gung Chung
Pages: 1043-1048
Published online on: 17 January 2012

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Article

TRESK gene recombinant adenovirus vector inhibits capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons

Jun Zhou, Shang-Long Yao, Cheng-Xiang Yang, Ji-Ying Zhong, Han-Bing Wang, Yan Zhang
Pages: 1049-1052
Published online on: 03 February 2012

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Article

The blues of P(16)INK(4a): Aberrant promoter methylation and association with colorectal cancer in the Kashmir valley

A. Syed Sameer, Safiya Abdullah, Saniya Nissar, Roohi Rasool, Zaffar A. Shah, Dil Afroze, Nissar A. Chowdri, Mushtaq A. Siddiqi
Pages: 1053-1057
Published online on: 03 January 2012

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Article

Polymorphisms in the 3'UTR of the human leptin gene and their role in hypertension

Qulsum Akhter, Akbar Masood, Ruhi Ashraf, Sabia Majid, Sabah Rasool, Tanzeela Khan, Tabasum Rashid, A. Syed Sameer, Bashir Ahmad Ganai
Pages: 1058-1062
Published online on: 04 January 2012

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Article

The JAK2-Akt-glycogen synthase kinase-3β signaling pathway is involved in toll-like receptor 2-induced monocyte chemoattractant protein-1 regulation

Dae-Weon Park, Hyung-Kyoung Lee, Tae-Whal Jeong, Jin-Sik Kim, Yoe-Sik Bae, Byung-Rho Chin, Suk-Hwan Baek
Pages: 1063-1067
Published online on: 03 January 2012

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Article

Effect of metformin on the proliferation, migration, and MMP-2 and -9 expression of human umbilical vein endothelial cells

Nilufar Esfahanian, Yadollah Shakiba, Behroz Nikbin, Hamid Soraya, Nasrin Maleki-Dizaji, Mahmood Ghazi-Khansari, Alireza Garjani
Pages: 1068-1074
Published online on: 12 January 2012

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Article

Downregulation of Id1 by small interfering RNA in gastric cancer inhibits cell growth via the Akt pathway

Guang Yang, Yan Zhang, Jianjun Xiong, Jing Wu, Changfu Yang, Hongbing Huang, Zhenyu Zhu
Pages: 1075-1079
Published online on: 12 January 2012

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Article

Changes in T lymphocyte subsets and intracellular cytokines after transfer of chemically extracted acellular nerve allografts

Wei Li, Wen-Wen Wu, Xing-Shi Lin, Shu-Xun Hou, Hong-Bin Zhong, Di-Ke Ruan
Pages: 1080-1086
Published online on: 09 January 2012

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Article

Correlation between hammerhead ribozyme-mediated eggshell protein gene cleavage and reproduction inhibition of Schistosoma japonicum

Yu Liang, Yuelan Zhou, Weiguo Yin, Yingju Li, Qiulin Yang, Yuan Gao, Yukuai Zhang, Yaofei Yang, Li Peng, Jianhua Xiao
Pages: 1087-1091
Published online on: 12 January 2012

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Article

Association between γ-glutamyltransferase and prehypertension

Xuzhen Qin, Guodong Tang, Ling Qiu, Tao Xu, Xinqi Cheng, Shaomei Han, Guangjin Zhu, Yajun Liu
Pages: 1092-1098
Published online on: 20 January 2012

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Article

Steroid receptor coactivator-3 differentially regulates the inflammatory response in peritoneal macrophages

Jun Li, Ying-Hai Liu, Shan Ou, Xue-Mei Dai, Jun-Ping Wang, Yong-Ping Su
Pages: 1099-1105
Published online on: 12 January 2012

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Article

Reduced levels of p15INK4b, p16INK4a, p21cip1 and p27kip1 in pancreatic carcinoma

Gang Li, Yuan Ji, Chen Liu, JingQi Li, YingQi Zhou
Pages: 1106-1110
Published online on: 30 January 2012

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Article

The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's disease

Erik Portelius, Juan Fortea, Jose Luis Molinuevo, Mikael K. Gustavsson, Ulf Andreasson, Raquel Sanchez-Valle
Pages: 1111-1115
Published online on: 01 February 2012

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Article

Aldehyde dehydrogenase activity is a cancer stem cell marker of tongue squamous cell carcinoma

Bo Zou, Shoujuan Sun, Xiaojuan Qi, Ping Ji
Pages: 1116-1120
Published online on: 03 February 2012

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Article

Defective activities, but not secretions, resulting from gene point mutations of human mannan-binding lectin

Ying Liu, Feng-Ling Liu, Zhi-Jun Bai, Na Zhao, Li-Yun Zhang, Xiao Lu, Zheng-Liang Chen
Pages: 1121-1127
Published online on: 06 February 2012

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Article Open Access

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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Article Open Access

CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Article Open Access

Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Review Open Access

Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Review Open Access

Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

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Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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