Evaluation of HOXB13 as a molecular marker of recurrent prostate cancer

C Abate-ShenDeregulated homeobox gene expression in cancer: cause or consequence?Nat Rev Cancer2777785200210.1038/nrc90712360280

R Bhatia-GaurAA DonjacourPJ SciavolinoRoles for Nkx3.1 in prostate development and cancerGenes Dev13966977199910.1101/gad.13.8.966

C BowenL BubendorfHJ VoellerLoss of NKX3.1 expression in human prostate cancers correlates with tumor progressionCancer Res6061116115200011085535

MJ KimR Bhatia-GaurWA Banach-PetroskyNkx3.1 mutant mice recapitulate early stages of prostate carcinogenesisCancer Res6229993004200212036903

A FeberJ ClarkG GoodwinAmplification and overexpression of E2F3 in human bladder cancerOncogene2316271630200410.1038/sj.onc.120727414716298

L HoodJR HeathME PhelpsB LinSystems biology and new technologies enable predictive and preventative medicineScience306640643200410.1126/science.110463515499008

T SreenathA OroszK FujitaCJ BieberichAndrogen-independent expression of hoxb-13 in the mouse prostateProstate41203207199910.1002/(SICI)1097-0045(19991101)41:3%3C203::AID-PROS8%3E3.0.CO;2-J10517879

Y TakahashiJ HamadaK MurakawaExpression profiles of 39 HOX genes in normal human adult organs and anaplastic thyroid cancer cell lines by quantitative real-time RT-PCR systemExp Cell Res293144153200410.1016/j.yexcr.2003.09.02414729064

KD EconomidesMR CapecchiHoxb13 is required for normal differentiation and secretory function of the ventral prostateDevelopment13020612069200310.1242/dev.0043212668621

C JungRS KimHJ ZhangSJ LeeMH JengHOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signalingCancer Res6491859192200410.1158/0008-5472.CAN-04-133015604291

YR KimKJ OhRY ParkHOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signalingMol Cancer9124201010.1186/1476-4598-9-12420504375

XJ MaZ WangPD RyanA two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifenCancer Cell5607616200410.1016/j.ccr.2004.05.015

LG KomuvesXK MaE StelnickiS RozenfeldY OdaC LargmanHOXB13 homeodomain protein is cytoplasmic throughout fetal skin developmentDev Dyn227192202200310.1002/dvdy.1029012761847

SM DhanasekaranTR BarretteD GhoshDelineation of prognostic biomarkers in prostate cancerNature412822826200110.1038/3509058511518967

DR RhodesMG SandaAP OtteAM ChinnaiyanMA RubinMultiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancerJ Natl Cancer Inst95661668200310.1093/jnci/95.9.66112734317

MA RubinM ZhouSM Dhanasekaranalpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancerJAMA28716621670200210.1001/jama.287.13.166211926890

CS FosterA FalconerAR DodsonTranscription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcomeOncogene2358715879200410.1038/sj.onc.120780015184867

AW PartinMW KattanEN SubongCombination of prostate-specific antigen, clinical stage, and Gleason score to predict pathological stage of localized prostate cancer. A multi-institutional updateJAMA27714451451199710.1001/jama.1997.03540420041027

Y ZhaoT YamashitaM IshikawaRegulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancerOncol Rep13721726200515756448

S EdwardsC CampbellP FlohrExpression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancerBr J Cancer92376381200510.1038/sj.bjc.660226115583692

JF ReidL LusaL De CeccoLimits of predictive models using microarray data for breast cancer clinical treatment outcomeJ Natl Cancer Inst97927930200510.1093/jnci/dji153

H OkudaM ToyotaW IshidaEpigenetic inactivation of the candidate tumor suppressor gene HOXB13 in human renal cell carcinomaOncogene2517331742200610.1038/sj.onc.120920016278676

KD EconomidesL ZeltserMR CapecchiHoxb13 mutations cause overgrowth of caudal spinal cordand tail vertebraeDev Biol256317330200310.1016/S0012-1606(02)00137-912679105