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Molecular Medicine Reports
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April 2012 Volume 5 Issue 4

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Article

Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

  • Authors:
    • Evanthia Kousi
    • Ioannis Tsougos
    • Konstantinos Fountas
    • Kiriaki Theodorou
    • Evaggelia Tsolaki
    • Ioannis Fezoulidis
    • Eftichia Kapsalaki
  • View Affiliations / Copyright

    Affiliations: Department of Medical Physics, University of Thessaly, Biopolis, Larissa 41110, Greece, Department of Neurosurgery, University of Thessaly, Biopolis, Larissa 41110, Greece, Department of Diagnostic Radiology, University of Thessaly, Biopolis, Larissa 41110, Greece
  • Pages: 1011-1018
    |
    Published online on: January 30, 2012
       https://doi.org/10.3892/mmr.2012.773
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Abstract

The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 ppm observed in low TE spectra adequately differentiated meningioma from other brain tumors while alanine was not indicative of meningioma occurrence; the presence of lipids and lactate did not provide a strong index for meningioma malignancy.
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Copy and paste a formatted citation
Spandidos Publications style
Kousi E, Tsougos I, Fountas K, Theodorou K, Tsolaki E, Fezoulidis I and Kapsalaki E: Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases. Mol Med Rep 5: 1011-1018, 2012.
APA
Kousi, E., Tsougos, I., Fountas, K., Theodorou, K., Tsolaki, E., Fezoulidis, I., & Kapsalaki, E. (2012). Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases. Molecular Medicine Reports, 5, 1011-1018. https://doi.org/10.3892/mmr.2012.773
MLA
Kousi, E., Tsougos, I., Fountas, K., Theodorou, K., Tsolaki, E., Fezoulidis, I., Kapsalaki, E."Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases". Molecular Medicine Reports 5.4 (2012): 1011-1018.
Chicago
Kousi, E., Tsougos, I., Fountas, K., Theodorou, K., Tsolaki, E., Fezoulidis, I., Kapsalaki, E."Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases". Molecular Medicine Reports 5, no. 4 (2012): 1011-1018. https://doi.org/10.3892/mmr.2012.773
Copy and paste a formatted citation
x
Spandidos Publications style
Kousi E, Tsougos I, Fountas K, Theodorou K, Tsolaki E, Fezoulidis I and Kapsalaki E: Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases. Mol Med Rep 5: 1011-1018, 2012.
APA
Kousi, E., Tsougos, I., Fountas, K., Theodorou, K., Tsolaki, E., Fezoulidis, I., & Kapsalaki, E. (2012). Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases. Molecular Medicine Reports, 5, 1011-1018. https://doi.org/10.3892/mmr.2012.773
MLA
Kousi, E., Tsougos, I., Fountas, K., Theodorou, K., Tsolaki, E., Fezoulidis, I., Kapsalaki, E."Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases". Molecular Medicine Reports 5.4 (2012): 1011-1018.
Chicago
Kousi, E., Tsougos, I., Fountas, K., Theodorou, K., Tsolaki, E., Fezoulidis, I., Kapsalaki, E."Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases". Molecular Medicine Reports 5, no. 4 (2012): 1011-1018. https://doi.org/10.3892/mmr.2012.773
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