Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

Kousi,Evanthia; Tsougos,Ioannis; Fountas,Konstantinos; Theodorou,Kiriaki; Tsolaki,Evaggelia; Fezoulidis,Ioannis; Kapsalaki,Eftichia

doi:10.3892/mmr.2012.773

Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

Authors:
- Evanthia Kousi
- Ioannis Tsougos
- Konstantinos Fountas
- Kiriaki Theodorou
- Evaggelia Tsolaki
- Ioannis Fezoulidis
- Eftichia Kapsalaki
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Affiliations: Department of Medical Physics, University of Thessaly, Biopolis, Larissa 41110, Greece, Department of Neurosurgery, University of Thessaly, Biopolis, Larissa 41110, Greece, Department of Diagnostic Radiology, University of Thessaly, Biopolis, Larissa 41110, Greece
Published online on: January 30, 2012 https://doi.org/10.3892/mmr.2012.773
Pages: 1011-1018

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Abstract

The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 ppm observed in low TE spectra adequately differentiated meningioma from other brain tumors while alanine was not indicative of meningioma occurrence; the presence of lipids and lactate did not provide a strong index for meningioma malignancy.

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