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Article

Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri

  • Authors:
    • Jianping Zhang
    • Lanlan Feng
    • Yi Lu
    • Dongxia Guo
    • Tengteng Xi
    • Xiaochun Wang
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China, Department of Anatomy, Medical College, Soochow University, Suzhou, Jiangsu 215123, P.R. China
  • Pages: 1458-1464
    |
    Published online on: March 6, 2013
       https://doi.org/10.3892/mmr.2013.1360
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Abstract

To investigate the distribution of lymphatic tissues and nerves in the supporting ligaments around the cervix uteri for their tomographical relationship, 9 adult female cadavers were used in this study. Following the incision of all supporting ligaments around the cervix, hematoxylin and esosin (H&E) and immunohistochemical staining of various sections of these ligaments was performed to enable the distribution of lymph tissues and autonomic nerves to be observed. Four lymph nodes were identified in three cadaver specimens. Three lymph nodes were present at a distance of 2.0 cm from the cervix in the cranial side of the cardinal ligaments (CLs), and one lymph node was located at a distance of 4.0 cm from the cervix in the cranial side of the uterosacral ligament (USL). The lymphatic vessels were dispersed in the CLs, scattered in the cervical side of the USLs, and occasionally distributed in the vesicouterine ligaments (VULs). In the CLs, parasympathetic nerves were located at the pelvic lateral wall and went downwards and medially into the cervix, while sympathetic fibers were located in the middle and lower parts of the ligaments. In the USLs, the autonomic nerves, which consisted primarily of sympathetic fibers, went downwards and laterally from the pelvic wall to the cervix. In the VULs, parasympathetic and sympathetic nerves were located in the inner sides of the vesical veins in the deep layers of the ligaments. It is concluded that there are few lymphatic tissues in the supporting ligaments around the cervix uteri, and that nerve‑sparing radical hysterectomy (NSRH) may be a safe method for the treatment of early‑stage cervical cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang J, Feng L, Lu Y, Guo D, Xi T and Wang X: Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri. Mol Med Rep 7: 1458-1464, 2013.
APA
Zhang, J., Feng, L., Lu, Y., Guo, D., Xi, T., & Wang, X. (2013). Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri. Molecular Medicine Reports, 7, 1458-1464. https://doi.org/10.3892/mmr.2013.1360
MLA
Zhang, J., Feng, L., Lu, Y., Guo, D., Xi, T., Wang, X."Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri". Molecular Medicine Reports 7.5 (2013): 1458-1464.
Chicago
Zhang, J., Feng, L., Lu, Y., Guo, D., Xi, T., Wang, X."Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri". Molecular Medicine Reports 7, no. 5 (2013): 1458-1464. https://doi.org/10.3892/mmr.2013.1360
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang J, Feng L, Lu Y, Guo D, Xi T and Wang X: Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri. Mol Med Rep 7: 1458-1464, 2013.
APA
Zhang, J., Feng, L., Lu, Y., Guo, D., Xi, T., & Wang, X. (2013). Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri. Molecular Medicine Reports, 7, 1458-1464. https://doi.org/10.3892/mmr.2013.1360
MLA
Zhang, J., Feng, L., Lu, Y., Guo, D., Xi, T., Wang, X."Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri". Molecular Medicine Reports 7.5 (2013): 1458-1464.
Chicago
Zhang, J., Feng, L., Lu, Y., Guo, D., Xi, T., Wang, X."Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri". Molecular Medicine Reports 7, no. 5 (2013): 1458-1464. https://doi.org/10.3892/mmr.2013.1360
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