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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2013 Volume 7 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Apelin elevates blood pressure in ICR mice with L‑NAME‑induced endothelial dysfunction

Katsumasa Nagano, Junji Ishida, Madoka Unno, Tanomu Matsukura, Akiyoshi Fukamizu
Pages: 1371-1375
Published online on: 15 March 2013

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Article

Expression and biological role of CIP2A in human astrocytoma

Fuxin Yi, Weimin Ni, Weixian Liu, Jinyang Bai, Wenbin Li
Pages: 1376-1380
Published online on: 05 March 2013

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Article Open Access

Clinical significance of keratinocyte growth factor and K-sam gene expression in gastric cancer

Hideki Tani, Noboru Saito, Makio Kobayashi, Shingo Kameoka
Pages: 1381-1386
Published online on: 27 March 2013

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Article

Overexpression of AKT decreases the chemosensitivity of gastric cancer cells to cisplatin in vitro and in vivo

Ling-li Zhang, Jun Zhang, Lei Shen, Xi-ming Xu, Hong-gang Yu
Pages: 1387-1390
Published online on: 28 March 2013

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Article

Combined CT angiography and SPECT myocardial perfusion imaging for the detection of functionally relevant coronary stenoses

Jian‑Ming Li, Rong‑Fang Shi, Li‑Ren Zhang, Ting Li, Zhi Dong
Pages: 1391-1396
Published online on: 04 March 2013

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Article

In vivo dynamic monitoring of the biological behavior of labeled C6 glioma by MRI

Jichun Liao, Rui Xia, Ting Liu, Hua Feng, Hua Ai, Bin Song, Fabao Gao
Pages: 1397-1402
Published online on: 13 March 2013

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Article

Crude extract of Euphorbia formosana inhibits the migration and invasion of DU145 human prostate cancer cells: The role of matrix metalloproteinase-2/9 inhibition via the MAPK signaling pathway

Jiun-Long Yang, Ju-Hwa Lin, Shu-Wen Weng, Jaw-Chyun Chen, Jai-Sing Yang, Sakae Amagaya, Shinji Funayana, W. Gibson Wood, Chao-Lin Kuo, Jing-Gung Chung
Pages: 1403-1408
Published online on: 20 March 2013

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Article

Overexpression of hTERT in potentially malignant colorectal laterally spreading tumors

Jun Li, Xun Cao, Yi Fang, Zhen-Er Liao, Yu-Ying Liu, Bi-Dan Huang, Yu-Jing Han
Pages: 1409-1412
Published online on: 15 March 2013

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Article

Expression and significance of PTEN and miR-92 in hepatocellular carcinoma

Bin Zhao, Yueting Zhu, Kai Cui, Jie Gao, Fachang Yu, Liang Chen, Sheng Li
Pages: 1413-1416
Published online on: 28 March 2013

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Article

Genome‑wide analysis of DNA methylation in rat lungs with lipopolysaccharide‑induced acute lung injury

Xiao‑Qiang Zhang, Chang‑Jun Lv, Xiang‑Yong Liu, Dong Hao, Jing  Qin, Huan‑Huan Tian, Yan Li, Xiao‑Zhi Wang
Pages: 1417-1424
Published online on: 28 March 2013

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Article

Effects of paeonol on intracellular calcium concentration and expression of RUNX3 in LoVo human colon cancer cells

Ming Li, Shi‑Yun Tan, Jun Zhang, Hong‑Xia You
Pages: 1425-1430
Published online on: 14 March 2013

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Article

Temporospatial expression and cellular localization of glutamine synthetase following traumatic spinal cord injury in adult rats

Chunxing Liu, Wenjie Wu, Bin Zhang, Jie Xiang, Jian Zou
Pages: 1431-1436
Published online on: 20 March 2013

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Article

A novel chimeric peptide binds MC3T3‑E1 cells to titanium and enhances their proliferation and differentiation

Dan Wang, Xiaofu Liao, Xu Qin, Wei Shi, Bin Zhou
Pages: 1437-1441
Published online on: 01 March 2013

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Article

Transcriptomic and proteomic analysis of human hepatic stellate cells treated with natural taurine

Jian Liang, Xin Deng, Fa-Sheng Wu, Yan-Fang Tang
Pages: 1442-1452
Published online on: 20 March 2013

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Article

Amygdalin inhibits renal fibrosis in chronic kidney disease

Junqi Guo, Weizheng Wu, Mingxiong Sheng, Shunliang Yang, Jianming Tan
Pages: 1453-1457
Published online on: 22 March 2013

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Article

Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri

Jianping Zhang, Lanlan Feng, Yi Lu, Dongxia Guo, Tengteng Xi, Xiaochun Wang
Pages: 1458-1464
Published online on: 06 March 2013

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Article

Cardiomyocyte differentiation of perinatally‑derived mesenchymal stem cells

Kuneerat Nartprayut, Yaowalak U‑Pratya, Pakpoom Kheolamai, Sirikul Manochantr, Methichit Chayosumrit, Surapol Issaragrisil, Aungkura Supokawej
Pages: 1465-1469
Published online on: 04 March 2013

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Article

Levels of leptin and IL-6 in lungs and blood are associated with the severity of chronic obstructive pulmonary disease in patients and rat models

Rui Liang, Wei Zhang, Ya-Mei Song
Pages: 1470-1476
Published online on: 15 March 2013

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Article

Overexpression of C10orf116 promotes proliferation, inhibits apoptosis and enhances glucose transport in 3T3-L1 adipocytes

Ling Chen, Xiao-Guang Zhou, Xiao-Yu Zhou, Chun Zhu, Chen-Bo Ji, Chun-Mei Shi, Jie Qiu, Xi-Rong Guo
Pages: 1477-1481
Published online on: 01 March 2013

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Article

Expression of 11β-HSD in steroid-induced avascular necrosis of the femoral head

Lin Wang, Deng-Ke Luo, Zhen-Yu Pan
Pages: 1482-1486
Published online on: 28 March 2013

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Article

Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-α, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro

Yao-Li Chen, Meng-Yi Yan, Su-Yu Chien, Shou-Jen Kuo, Dar‑Ren Chen, Chun-Yuan Cheng, Chin-Cheng Su
Pages: 1487-1493
Published online on: 20 March 2013

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Article

Expression of basigin in the early phase of acute myocardial ischemia in rats

Yun Liu, Wei‑Bo Liang, Lu‑Shun Zhang, Lin‑Bo Gao, Tian‑Yi Chen, Yan‑Yun Wang, Lin Zhang
Pages: 1494-1500
Published online on: 20 March 2013

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Article

Knockdown of autophagy-related gene BECLIN1 promotes cell growth and inhibits apoptosis in the A549 human lung cancer cell line

Wenyu Wang, Hongkun Fan, Yun Zhou, Ping Duan, Guoqiang Zhao, Gang Wu
Pages: 1501-1505
Published online on: 19 March 2013

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Article

microRNA expression profiling in multidrug resistance of the 5‑Fu‑induced SGC‑7901 human gastric cancer cell line

Yan Wang, Xiaodong Gu, Zhenyang Li, Jianbin Xiang, Jianhai Jiang, Zongyou Chen
Pages: 1506-1510
Published online on: 20 March 2013

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Article

Synergistic protective effects of escin and low‑dose glucocorticoids on blood‑retinal barrier breakdown in a rat model of retinal ischemia

Fenglan Zhang, Yuanbin Li, Leiming Zhang, Guoying Mu
Pages: 1511-1515
Published online on: 15 March 2013

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Article

Electroacupuncture ameliorates cognitive impairment through inhibition of NF-κB-mediated neuronal cell apoptosis in cerebral ischemia-reperfusion injured rats

Xiaodong Feng, Shanli Yang, Jiao Liu, Jia Huang, Jun Peng, Jiumao Lin, Jing Tao, Lidian Chen
Pages: 1516-1522
Published online on: 22 March 2013

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Article

Electrical stimulation enhances peripheral nerve regeneration after crush injury in rats

Xu Zhang, Na Xin, Lei Tong, Xiao-Jie Tong
Pages: 1523-1527
Published online on: 26 March 2013

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Article

Effects of different states of oxidative stress on fetal rat alveolar type II epithelial cells in vitro and ROS‑induced changes in Wnt signaling pathway expression

Zhu Li, Fang Fang, Feng Xu
Pages: 1528-1532
Published online on: 20 March 2013

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Article

Effects of matrine on oval cell‑mediated liver regeneration and expression of RBP‑Jκ and HES1

Zhi‑Yun Yang, Li Wang, Yi‑Xin Hou, Xian‑Bo Wang
Pages: 1533-1538
Published online on: 27 March 2013

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Article

The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells

Yu-Ren Liao, Chi-Cheng Lu, Kuang-Chi Lai, Jai-Sing Yang, Sheng‑Chu Kuo, Yen-Fang Wen, Shinji Fushiya, Tian-Shung Wu
Pages: 1539-1544
Published online on: 05 March 2013

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Article

A unique case of female pseudohermaphroditism with 21-hydroxylase deficiency and small supernumerary marker chromosome 7

Walid Al-Achkar, Abdulsamad Wafa, Manar Assaad, Christian Ehlers, Thomas Liehr
Pages: 1545-1548
Published online on: 28 February 2013

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Article

Paired box 2 induces epithelial-mesenchymal transition in normal renal tubular epithelial cells of rats

Li Li, Yubin Wu, Yongchang Yang
Pages: 1549-1554
Published online on: 12 March 2013

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Article

Antitumor activity of bee pollen polysaccharides from Rosa rugosa

Bo Wang, Qiyu Diao, Zhongyu Zhang, Yang Liu, Qipin Gao, Yifa Zhou, Shanshan Li
Pages: 1555-1558
Published online on: 20 March 2013

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Article

The mechanism through which octreotide inhibits hepatic stellate cell activity

Jingjing Wang, Lin Wang, Guanhua Song, Bo Han
Pages: 1559-1564
Published online on: 20 March 2013

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Article

Morroniside promotes bone marrow mesenchymal stem cell proliferation in rats

Naiwu Hu, Shujun Ren, Wei Li, Tao Zhang, Chengbin Zhao
Pages: 1565-1570
Published online on: 28 March 2013

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Article

Alzheimer's phenotypes induced by overexpression of human presenilin 2 mutant proteins stimulate significant changes in key factors of glucose metabolism

Young Ju Lee, Ji Eun Kim, In Sik Hwang, Moon Hwa Kwak, Jae Ho Lee, Young Jin Jung, Beum Soo An, Hyeog Soong Kwon, Byoung Chul Kim, Seon Jong Kim, Joo Man Kim, Dae Youn Hwang
Pages: 1571-1578
Published online on: 28 March 2013

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Article

miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling

Yong Chen, Ying Sun, Longbang Chen, Xingxiang Xu, Xizhi Zhang, Buhai Wang, Lingfeng Min, Wei Liu
Pages: 1579-1584
Published online on: 28 March 2013

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Article

Bigelovii A induces apoptosis of HL‑60 human acute promyelocytic leukaemia cells

Fuqin Guan, Haiting Wang, Yu Shan, Dongmei Zhang, Youyi Zhao, Yu Chen, Qizhi Wang, Ming Wang, Xu Feng
Pages: 1585-1590
Published online on: 01 March 2013

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Article

Differentially expressed kinase genes associated with trypsinogen activation in rat pancreatic acinar cells treated with taurolithocholic acid 3-sulfate

Biao Ma, Lin Wu, Ming Lu, Bo Gao, Xin Qiao, Bei Sun, Dongbo Xue, Weihui Zhang
Pages: 1591-1596
Published online on: 04 March 2013

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Article

The viable Mycobacterium tuberculosis H37Ra strain induces a stronger mouse macrophage response compared to the heat-inactivated H37Rv strain

Zong-Lin He, Fa-Wang Du, Xian-Zhi Du
Pages: 1597-1602
Published online on: 08 March 2013

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Article

High-flux dialysis improves pulmonary ventilation function in uremic patients

Hui Lin, Yong-Gui Wu, Jiang-Huai Zhang, Ming Kan
Pages: 1603-1606
Published online on: 14 March 2013

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Article

Protective effects of Lagerstroemia speciosa on 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in HIT-T15 pancreatic β cells

Jia-Le Song, Xin Zhao, Qiang Wang, Ting Zhang
Pages: 1607-1612
Published online on: 26 March 2013

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Article

Ilex kudingcha C.J. Tseng (Kudingcha) prevents HCl/ethanol‑induced gastric injury in Sprague‑Dawley rats

Xin Zhao, Qiang Wang, Yu Qian, Jia-Le Song
Pages: 1613-1616
Published online on: 28 March 2013

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Article

Mesenchymal stem cells overexpressing integrin-linked kinase attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions

Qing Mao, Cheng-Xi Lin, Xiu-Lin Liang, Jian-Shu Gao, Biao Xu
Pages: 1617-1623
Published online on: 28 February 2013

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Article

Effects of Bauhinia championii (Benth.) Benth. polysaccharides on the proliferation and cell cycle of chondrocytes

Liangliang Cai, Hongzhi Ye, Fangrong Yu, Huiting Li, Jiashou Chen, Xianxiang Liu
Pages: 1624-1630
Published online on: 13 March 2013

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Article

DNA integrity is a critical molecular indicator for the assessment of male infertility

Huda Mossa Omran, Moiz Bakhiet, Mariam Ghloom Dashti
Pages: 1631-1635
Published online on: 21 March 2013

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Article

The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro

Xiaodong Sun, Fang Han, Junling Yi, Ningning Hou, Zhibin Cao
Pages: 1636-1640
Published online on: 28 February 2013

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Article

NS-398 enhances the efficacy of bortezomib against RPMI8226 human multiple myeloma cells

Wenzhong Que, Saiyuan Li, Junmin Chen
Pages: 1641-1645
Published online on: 26 March 2013

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Article

Signaling network of OSW‑1‑induced apoptosis and necroptosis in hepatocellular carcinoma

Jichun Jin, Xinglin Jin, Changshi Qian, Yang Ruan , Hao Jiang
Pages: 1646-1650
Published online on: 13 March 2013

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Article

RNA interference‑mediated inhibition of survivin and VEGF in pancreatic cancer cells in vitro

Jianlin Song, Lipin Cao, Yixiong Li
Pages: 1651-1655
Published online on: 06 March 2013

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Article

The pyrimidine analog FNC inhibits cell proliferation and viral protein synthesis in HTLV‑1‑infected cells

Jinheng Wang, Xia Wang, Cai Gao, Xiangfeng Song, Zhiguo Niu, Zhitao Gao, Zhihai Qin, Junbiao Chang, Hui Wang
Pages: 1656-1660
Published online on: 05 March 2013

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Article

Activation of spinal ERK1/2 contributes to mechanical allodynia in a rat model of postoperative pain

Xu‑Dan Shi, Di Fu, Jun‑Mei Xu, Yan‑Ling Zhang, Ru‑Ping Dai
Pages: 1661-1665
Published online on: 28 February 2013

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Article

Interaction between cAMP, volume‑regulated anion channels and the Na+‑HCO3‑‑cotransporter, NBCe1, in the regulation of nutrient‑ and hypotonicity‑induced insulin release from isolated rat pancreatic islets and tumoral insulin‑producing BRIN‑BD11 cells

Nurdan Bulur, Raphael Crutzen, Willy J. Malaisse, Abdullah Sener, Renaud Beauwens, Philippe Golstein
Pages: 1666-1672
Published online on: 28 February 2013

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Article

Ursolic acid induces apoptosis via Akt/NF-κB signaling suppression in T24 human bladder cancer cells

Long Gai, Na Cai, Lingling Wang, Xiaoyi Xu, Xiangbo Kong
Pages: 1673-1677
Published online on: 11 March 2013

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Article

Overexpression of high mobility group protein B1 correlates with the proliferation and metastasis of lung adenocarcinoma cells

Ke-Kang Sun, Cheng Ji, Xing Li, Lu Zhang, Jun Deng, Ning Zhong, Xiao-Yang Wu
Pages: 1678-1682
Published online on: 06 March 2013

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Article

Effects of edaravone on the expression of β-defensin-2 mRNA in lung tissue of rats with myocardial ischemia reperfusion

Weiwei Zhang, Yongqing Guo, Shuzhen Yu, Jianfeng Wei, Jianmin Jin
Pages: 1683-1687
Published online on: 22 March 2013

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Article

siRNA targeting of PRDX3 enhances cisplatin‑induced apoptosis in ovarian cancer cells through the suppression of the NF‑κB signaling pathway

Jie Duan, Yan Lang, Chengwen Song, Jun Xiong, Yan Wang, Yang Yan
Pages: 1688-1694
Published online on: 14 March 2013

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Article

Transforming growth factor-β1 gene mutations and phenotypes in pediatric patients with Camurati‑Engelmann disease

Chun Wang, Bao-Hong Zhang, Yu-Juan Liu, Yun-Qiu Hu, Jin-Wei He, Zhen-Lin Zhang
Pages: 1695-1699
Published online on: 13 March 2013

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Article

Comparative proteomic analysis of ductal breast carcinoma demonstrates an altered expression of chaperonins and cytoskeletal proteins

Paolo Carcoforo, Blendi Ura, Carlo Mischiati, Monica Squerzanti, Vincenzo Lanzara, Carlo Cervellati, Roberta Calza, Patrizia Polverino De Laureto, Erica Frare, Mattia Portinari, Giordana Feriotto, Serena Lanzara, Enzo Agostinelli, Carlo M. Bergamini
Pages: 1700-1704
Published online on: 15 March 2013

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Article

Effect of histone deacetylase inhibitors on cell apoptosis and expression of the tumor suppressor genes RUNX3 and ARHI in ovarian tumors

Lan Zhang, Peishu Liu, Hua Li, Fuying Xue
Pages: 1705-1709
Published online on: 14 March 2013

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Article

Developmental delay referrals and the roles of Fragile X testing and molecular karyotyping: A New Zealand perspective

Elaine Doherty, Rachel O'Connor, Anna Zhang, Christina Lim, Jennifer M. Love, Fern Ashton, Karen Claxton, Nerine Gregersen, Alice M. George, Donald R. Love
Pages: 1710-1714
Published online on: 20 March 2013

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Journal Cover
December-2026 Volume 34 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Elabela in pregnancy: Physiology, associated disorders and translational perspectives (Review)

Yibei Xie, Shujun Yang, Cuicui Meng, Xuxiang Chen, Huibao Long, Haidong Wu, Tong Wang
Article Number: 347
Published online on: 02 November 2026

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Graphene‑based nanomaterials for drug delivery: Design strategies, mechanisms and clinical perspectives (Review)

Haichao Liu, Hongxian Yan, Shaopeng Liu, Yifei Xue, Jiajia Huang, Shuangshuang Li
Article Number: 346
Published online on: 30 October 2026

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Review Open Access

Pathological regulatory roles of lysine acylation modifications in idiopathic pulmonary fibrosis (Review)

Mingyan Li, Zhong Yan, Baoming Peng, Fuzhou Yang, Min Ye, Yue Zheng, Mingshuang Wang, Ruke Zhang, Sha Li, Yuanshuai Huang
Article Number: 345
Published online on: 30 October 2026

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Mitochondrial dysfunction in metabolic dysfunction-associated steatotic liver disease: Mechanistic insights and therapeutic horizons (Review)

Jiayuan Chen, Haoran Zhong, Jing Li, Hao Chen, Wenguang Fu
Article Number: 344
Published online on: 29 October 2026

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Review Open Access

Role of glucagon‑like peptide‑1 receptor in cancer: Mechanisms and pharmacologic intervention (Review)

Feng Jing, Ying Zeng, Qin-Ling Yu, Chao-Ju Fu
Article Number: 343
Published online on: 27 October 2026

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Review Open Access

A false sense of hypoxia: Pro‑tumorigenic VHL‑HIF2α dysregulation in clear cell renal cell carcinoma (Review)

Nur Qurratu' Athirah A Rahman, Ahmad Suhail Khazali, Mohamad Aiman Mohtar, Saiful Effendi Syafruddin
Article Number: 342
Published online on: 23 October 2026

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Research progress in neural regulatory mechanisms and targeted therapy of obesity (Review)

Dejie Kang, Xia Li, Yaoyou Zhang, Yihan Sun, Yuhan Li, Zhiyan Yao, Youlei Li
Article Number: 341
Published online on: 22 October 2026

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Mechanisms of the interaction between aging of the male reproductive system and obesity, and clinical management strategies (Review)

Dandan Luo, Lulu Zhang, Xiangyu Qi, Qiangbo Guan, Feng Xu, Peng Lu, Chunxiao Yu
Article Number: 340
Published online on: 22 October 2026

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Erythropoietin beyond red blood cells: Systemic and oncological functions (Review)

Kristína Danková, Zuzana Solárová, Pavol Harvanik, Martina Šemeláková, Peter Solár
Article Number: 339
Published online on: 22 October 2026

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Liquid‑liquid phase separation and post‑transcriptional regulation intersection: A new paradigm of RNA‑binding protein condensates in hepatocellular carcinoma malignant phenotypes (Review)

Xiao Liu, Yunyi Huang
Article Number: 338
Published online on: 21 October 2026

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Research advances in the interplay between ferroptosis and T cells in the tumor microenvironment (Review)

Shihan Tang, Wenbo Xu, Yichen Li, Chuwei Liu, Weitao Liu, Ruihan Liang, Qianhui Liao, Han Sun, Zhuoyan Wang, Lingchang Shi, Qiying Liu, Huiping Liu
Article Number: 337
Published online on: 21 October 2026

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Gut‑kidney axis in chronic kidney disease: Dysbiosis, uremic metabolites and therapeutic opportunities (Review) 

Yinding Wang, Hanyu Zeng, Na Liu, Dong Yang
Article Number: 336
Published online on: 16 October 2026

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Article Open Access

Glycyrrhizic acid attenuates corneal inflammation and pathological angiogenesis through FAK/PI3K/AKT signaling

Jinjin Yu, Huiheng Qu, Yinming Fang, Weicheng Xu, Nannan Ding, Jie Ji, Nan Wang, Wei Shi
Article Number: 335
Published online on: 15 October 2026

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Article Open Access

Erbin deficiency exacerbates sepsis‑induced liver injury through mitochondrial ROS/NLRP3‑mediated inflammatory responses

Jing Zuo, Xing Wang, Guoqing Jing, Xiaojing Wu, Xuemin Song
Article Number: 334
Published online on: 15 October 2026

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Gut microbiota in patients receiving dialysis: Mechanisms, complications and the road to personalized microbiome‑based care (Review)

Chenxia Jin, Yanping Wang
Article Number: 333
Published online on: 15 October 2026

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Article Open Access

Epigallocatechin gallate and thermal cycling‑stimulation synergistically promote apoptosis in A549 cells via endoplasmic reticulum stress‑induced calcium ion dysregulation and oxidative stress

Fang-Tzu Hsu, Hsu-Hsiang Liu, Yi Kung, Chieh-Jou Lin, Chih-Yu Chao
Article Number: 332
Published online on: 15 October 2026

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Article Open Access

Piezo1 knockdown alleviates high‑altitude cerebral edema by improving brain microvascular endothelial cell tight junctions via blocking the calcium influx‑mediated Calpain‑1 activity

Taijian Cao, Zhicheng Xiang, Yangyang Zhao, Drolma Gomchok, Haifeng Ma, Shiwang Li, Dahai Cao, Chunqing Yang, Qiang Zhang
Article Number: 331
Published online on: 13 October 2026

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Navigating the landscape of targeted therapies for renal cell carcinoma in the era of precision medicine (Review)

Hongguo Cui, Jingheng Song, Peisen Yang, Zhengchao Zhang, Yuanyuan Liu, Gang Zhang, Aimin Tian, Jizhong Che, Yangyang Liu, Hui Sun, Yankai Xu
Article Number: 330
Published online on: 13 October 2026

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Article Open Access

ΔNp63α‑mediated regulation of tumor‑associated genes and pathways in hepatocellular carcinoma progression

Xiaowen Lin, Anghui Peng, Min Zhang, Xinyang Yu
Article Number: 329
Published online on: 13 October 2026

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Article Open Access

 Leptin promotes obesity‑related osteoarthritis progression via CD44/JAK2/STAT3 axis‑mediated chondrocyte apoptosis

Hao Qiu, Chao Zeng, Cheng Chen, Xin Zhou, Yongjun Zhu, Zhongliang Deng
Article Number: 328
Published online on: 09 October 2026

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Mechanical‑immune feedback regulation in distraction osteogenesis: From mechanotransduction to immune microenvironment remodeling (Review)

Xian Wang, Yuetong Wang, Shixi He, Cheng Ma, Zhengzhong He, Xuanping Huang
Article Number: 327
Published online on: 08 October 2026

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Research progress in synergistic multimechanism of nanomaterial-mediated neuroinflammatory therapy (Review)

Heng Wang, Pei Yang, Wantao Liu
Article Number: 326
Published online on: 07 October 2026

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Retraction Open Access

[Retracted] (‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway

Jia-Wen Li, Xiao-Yun Wang, Xin Zhang, Lei Gao, Li-Feng Wang, Xin-Hua Yin
Article Number: 325
Published online on: 05 October 2026

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Lactylation and exercise: A molecular link to disease alleviation (Review)

Jian Wang, Lei Wu
Article Number: 324
Published online on: 02 October 2026

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January-2027 Volume 35 Issue 1

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

PINK1‑regulated mitophagy dysfunction in the pathogenesis of Parkinson's disease (Review)

Han-Liang Dan, Shu-Er Liu, Yu-Jie Zhao, Zi-Fan Zhu, Hao-Gang Li, Yi-Xiang Huang, Mei Chen, Yi-Hui Zhang, Hui-Xin Ai, Xiao-Hui Huang, Hai-Yun Zhao, Zheng Liu, Pan Zou, Maslinda Musa
Article Number: 11
Published online on: 12 November 2026

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Mitochondrial LONP1: Linking structure and function to context‑dependent roles in disease (Review)

Du Chen, Qifeng Li, Yuanxi Zhang, Zehua Zhang, Dengqiu Xu
Article Number: 10
Published online on: 11 November 2026

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Article Open Access

Artemether prevents renal proximal tubules enlargement in high‑fat diet induced obese mice

Wenci Weng, Lingling Shen, Honghong Liu, Yating Zhang, Xuewen Yu, Mumin Shao, Huili Sun, Pengxun Han
Article Number: 9
Published online on: 11 November 2026

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Expression of Concern Open Access

[Expression of Concern] Somatic mutations in myeloid cell leukemia‑1 contribute to the pathogenesis of glioma by prolonging its half‑life

Xiupeng Lv, Guang Tan, Yiqun Yao, Li Lv, Xiaoqin Deng, Lei Dong, Shuang Li, Linlin Li, Yinghui Xu
Article Number: 8
Published online on: 09 November 2026

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Role of protein lactylation in pulmonary and cardiovascular diseases: Current research and future perspectives (Review)

Zi-An Pan, Li-Ting Tong, Zhe-Min Wang
Article Number: 7
Published online on: 06 November 2026

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Microglia promote infiltration and polarization of macrophages in cerebral ischemia‑reperfusion via the reactive oxygen species‑SPI1‑CCL9 axis 

Xianfeng Kuang, Zhangxiang Peng, Yao Yang, Shaoquan Pu, Mou Zhang, Jiayue Wang, Jun Tao, Shixiang Li, Dong Zhan
Article Number: 6
Published online on: 06 November 2026

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Lactylation in the regulation of macrophage polarization: Mechanisms pathophysiological significance (Review)

Xiao-Yu Wang, Dong-Xu Liao, Lin Yang, Qin Xie, Qing-Qing Huang, Yi Wen
Article Number: 5
Published online on: 04 November 2026

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Hypoxia in lymphoma: Mechanistic remodeling of the tumor microenvironment, disease progression and therapeutic resistance (Review)

Yanan Zhu, Chaowei Zhang, Meirui Zhang, Qing Hong, Yuxuan Han, Xinyu Tang, Na Chen
Article Number: 4
Published online on: 03 November 2026

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Metabolic reprogramming of myeloid‑derived suppressor cells in colorectal cancer: Mechanistic insights and immunometabolic targeted rehabilitation (Review)

Liang-Xiao Zhu, Guang-Jie Jiang, Feng-Hou Gao, Yi-Qiao Du
Article Number: 3
Published online on: 03 November 2026

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Gene therapy for epilepsy: From SCN1A to broadened therapeutic horizons (Review)

Ruotong Qin, Xiaoge Hu, Wei Jiang, Jing Wang, Mei Zheng, Zhenqiang Zhang, Dongrui Ma
Article Number: 2
Published online on: 03 November 2026

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Expression of Concern Open Access

[Expression of Concern] D‑galactose induces astrocytic aging and contributes to astrocytoma progression and chemoresistance via cellular senescence

Jingang Hou, Yeejin Yun, Jianjie Xue, Mengqi  Sun, Sunchang  Kim
Article Number: 1
Published online on: 03 November 2026

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