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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2013 Volume 7 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Apelin elevates blood pressure in ICR mice with L‑NAME‑induced endothelial dysfunction

Katsumasa Nagano, Junji Ishida, Madoka Unno, Tanomu Matsukura, Akiyoshi Fukamizu
Pages: 1371-1375
Published online on: 15 March 2013

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Article

Expression and biological role of CIP2A in human astrocytoma

Fuxin Yi, Weimin Ni, Weixian Liu, Jinyang Bai, Wenbin Li
Pages: 1376-1380
Published online on: 05 March 2013

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Article Open Access

Clinical significance of keratinocyte growth factor and K-sam gene expression in gastric cancer

Hideki Tani, Noboru Saito, Makio Kobayashi, Shingo Kameoka
Pages: 1381-1386
Published online on: 27 March 2013

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Article

Overexpression of AKT decreases the chemosensitivity of gastric cancer cells to cisplatin in vitro and in vivo

Ling-li Zhang, Jun Zhang, Lei Shen, Xi-ming Xu, Hong-gang Yu
Pages: 1387-1390
Published online on: 28 March 2013

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Article

Combined CT angiography and SPECT myocardial perfusion imaging for the detection of functionally relevant coronary stenoses

Jian‑Ming Li, Rong‑Fang Shi, Li‑Ren Zhang, Ting Li, Zhi Dong
Pages: 1391-1396
Published online on: 04 March 2013

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Article

In vivo dynamic monitoring of the biological behavior of labeled C6 glioma by MRI

Jichun Liao, Rui Xia, Ting Liu, Hua Feng, Hua Ai, Bin Song, Fabao Gao
Pages: 1397-1402
Published online on: 13 March 2013

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Article

Crude extract of Euphorbia formosana inhibits the migration and invasion of DU145 human prostate cancer cells: The role of matrix metalloproteinase-2/9 inhibition via the MAPK signaling pathway

Jiun-Long Yang, Ju-Hwa Lin, Shu-Wen Weng, Jaw-Chyun Chen, Jai-Sing Yang, Sakae Amagaya, Shinji Funayana, W. Gibson Wood, Chao-Lin Kuo, Jing-Gung Chung
Pages: 1403-1408
Published online on: 20 March 2013

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Article

Overexpression of hTERT in potentially malignant colorectal laterally spreading tumors

Jun Li, Xun Cao, Yi Fang, Zhen-Er Liao, Yu-Ying Liu, Bi-Dan Huang, Yu-Jing Han
Pages: 1409-1412
Published online on: 15 March 2013

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Article

Expression and significance of PTEN and miR-92 in hepatocellular carcinoma

Bin Zhao, Yueting Zhu, Kai Cui, Jie Gao, Fachang Yu, Liang Chen, Sheng Li
Pages: 1413-1416
Published online on: 28 March 2013

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Article

Genome‑wide analysis of DNA methylation in rat lungs with lipopolysaccharide‑induced acute lung injury

Xiao‑Qiang Zhang, Chang‑Jun Lv, Xiang‑Yong Liu, Dong Hao, Jing  Qin, Huan‑Huan Tian, Yan Li, Xiao‑Zhi Wang
Pages: 1417-1424
Published online on: 28 March 2013

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Article

Effects of paeonol on intracellular calcium concentration and expression of RUNX3 in LoVo human colon cancer cells

Ming Li, Shi‑Yun Tan, Jun Zhang, Hong‑Xia You
Pages: 1425-1430
Published online on: 14 March 2013

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Article

Temporospatial expression and cellular localization of glutamine synthetase following traumatic spinal cord injury in adult rats

Chunxing Liu, Wenjie Wu, Bin Zhang, Jie Xiang, Jian Zou
Pages: 1431-1436
Published online on: 20 March 2013

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Article

A novel chimeric peptide binds MC3T3‑E1 cells to titanium and enhances their proliferation and differentiation

Dan Wang, Xiaofu Liao, Xu Qin, Wei Shi, Bin Zhou
Pages: 1437-1441
Published online on: 01 March 2013

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Article

Transcriptomic and proteomic analysis of human hepatic stellate cells treated with natural taurine

Jian Liang, Xin Deng, Fa-Sheng Wu, Yan-Fang Tang
Pages: 1442-1452
Published online on: 20 March 2013

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Article

Amygdalin inhibits renal fibrosis in chronic kidney disease

Junqi Guo, Weizheng Wu, Mingxiong Sheng, Shunliang Yang, Jianming Tan
Pages: 1453-1457
Published online on: 22 March 2013

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Article

Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri

Jianping Zhang, Lanlan Feng, Yi Lu, Dongxia Guo, Tengteng Xi, Xiaochun Wang
Pages: 1458-1464
Published online on: 06 March 2013

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Article

Cardiomyocyte differentiation of perinatally‑derived mesenchymal stem cells

Kuneerat Nartprayut, Yaowalak U‑Pratya, Pakpoom Kheolamai, Sirikul Manochantr, Methichit Chayosumrit, Surapol Issaragrisil, Aungkura Supokawej
Pages: 1465-1469
Published online on: 04 March 2013

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Article

Levels of leptin and IL-6 in lungs and blood are associated with the severity of chronic obstructive pulmonary disease in patients and rat models

Rui Liang, Wei Zhang, Ya-Mei Song
Pages: 1470-1476
Published online on: 15 March 2013

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Article

Overexpression of C10orf116 promotes proliferation, inhibits apoptosis and enhances glucose transport in 3T3-L1 adipocytes

Ling Chen, Xiao-Guang Zhou, Xiao-Yu Zhou, Chun Zhu, Chen-Bo Ji, Chun-Mei Shi, Jie Qiu, Xi-Rong Guo
Pages: 1477-1481
Published online on: 01 March 2013

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Article

Expression of 11β-HSD in steroid-induced avascular necrosis of the femoral head

Lin Wang, Deng-Ke Luo, Zhen-Yu Pan
Pages: 1482-1486
Published online on: 28 March 2013

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Article

Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-α, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro

Yao-Li Chen, Meng-Yi Yan, Su-Yu Chien, Shou-Jen Kuo, Dar‑Ren Chen, Chun-Yuan Cheng, Chin-Cheng Su
Pages: 1487-1493
Published online on: 20 March 2013

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Article

Expression of basigin in the early phase of acute myocardial ischemia in rats

Yun Liu, Wei‑Bo Liang, Lu‑Shun Zhang, Lin‑Bo Gao, Tian‑Yi Chen, Yan‑Yun Wang, Lin Zhang
Pages: 1494-1500
Published online on: 20 March 2013

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Article

Knockdown of autophagy-related gene BECLIN1 promotes cell growth and inhibits apoptosis in the A549 human lung cancer cell line

Wenyu Wang, Hongkun Fan, Yun Zhou, Ping Duan, Guoqiang Zhao, Gang Wu
Pages: 1501-1505
Published online on: 19 March 2013

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Article

microRNA expression profiling in multidrug resistance of the 5‑Fu‑induced SGC‑7901 human gastric cancer cell line

Yan Wang, Xiaodong Gu, Zhenyang Li, Jianbin Xiang, Jianhai Jiang, Zongyou Chen
Pages: 1506-1510
Published online on: 20 March 2013

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Article

Synergistic protective effects of escin and low‑dose glucocorticoids on blood‑retinal barrier breakdown in a rat model of retinal ischemia

Fenglan Zhang, Yuanbin Li, Leiming Zhang, Guoying Mu
Pages: 1511-1515
Published online on: 15 March 2013

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Article

Electroacupuncture ameliorates cognitive impairment through inhibition of NF-κB-mediated neuronal cell apoptosis in cerebral ischemia-reperfusion injured rats

Xiaodong Feng, Shanli Yang, Jiao Liu, Jia Huang, Jun Peng, Jiumao Lin, Jing Tao, Lidian Chen
Pages: 1516-1522
Published online on: 22 March 2013

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Article

Electrical stimulation enhances peripheral nerve regeneration after crush injury in rats

Xu Zhang, Na Xin, Lei Tong, Xiao-Jie Tong
Pages: 1523-1527
Published online on: 26 March 2013

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Article

Effects of different states of oxidative stress on fetal rat alveolar type II epithelial cells in vitro and ROS‑induced changes in Wnt signaling pathway expression

Zhu Li, Fang Fang, Feng Xu
Pages: 1528-1532
Published online on: 20 March 2013

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Article

Effects of matrine on oval cell‑mediated liver regeneration and expression of RBP‑Jκ and HES1

Zhi‑Yun Yang, Li Wang, Yi‑Xin Hou, Xian‑Bo Wang
Pages: 1533-1538
Published online on: 27 March 2013

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Article

The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells

Yu-Ren Liao, Chi-Cheng Lu, Kuang-Chi Lai, Jai-Sing Yang, Sheng‑Chu Kuo, Yen-Fang Wen, Shinji Fushiya, Tian-Shung Wu
Pages: 1539-1544
Published online on: 05 March 2013

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Article

A unique case of female pseudohermaphroditism with 21-hydroxylase deficiency and small supernumerary marker chromosome 7

Walid Al-Achkar, Abdulsamad Wafa, Manar Assaad, Christian Ehlers, Thomas Liehr
Pages: 1545-1548
Published online on: 28 February 2013

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Article

Paired box 2 induces epithelial-mesenchymal transition in normal renal tubular epithelial cells of rats

Li Li, Yubin Wu, Yongchang Yang
Pages: 1549-1554
Published online on: 12 March 2013

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Article

Antitumor activity of bee pollen polysaccharides from Rosa rugosa

Bo Wang, Qiyu Diao, Zhongyu Zhang, Yang Liu, Qipin Gao, Yifa Zhou, Shanshan Li
Pages: 1555-1558
Published online on: 20 March 2013

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Article

The mechanism through which octreotide inhibits hepatic stellate cell activity

Jingjing Wang, Lin Wang, Guanhua Song, Bo Han
Pages: 1559-1564
Published online on: 20 March 2013

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Article

Morroniside promotes bone marrow mesenchymal stem cell proliferation in rats

Naiwu Hu, Shujun Ren, Wei Li, Tao Zhang, Chengbin Zhao
Pages: 1565-1570
Published online on: 28 March 2013

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Article

Alzheimer's phenotypes induced by overexpression of human presenilin 2 mutant proteins stimulate significant changes in key factors of glucose metabolism

Young Ju Lee, Ji Eun Kim, In Sik Hwang, Moon Hwa Kwak, Jae Ho Lee, Young Jin Jung, Beum Soo An, Hyeog Soong Kwon, Byoung Chul Kim, Seon Jong Kim, Joo Man Kim, Dae Youn Hwang
Pages: 1571-1578
Published online on: 28 March 2013

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Article

miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling

Yong Chen, Ying Sun, Longbang Chen, Xingxiang Xu, Xizhi Zhang, Buhai Wang, Lingfeng Min, Wei Liu
Pages: 1579-1584
Published online on: 28 March 2013

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Article

Bigelovii A induces apoptosis of HL‑60 human acute promyelocytic leukaemia cells

Fuqin Guan, Haiting Wang, Yu Shan, Dongmei Zhang, Youyi Zhao, Yu Chen, Qizhi Wang, Ming Wang, Xu Feng
Pages: 1585-1590
Published online on: 01 March 2013

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Article

Differentially expressed kinase genes associated with trypsinogen activation in rat pancreatic acinar cells treated with taurolithocholic acid 3-sulfate

Biao Ma, Lin Wu, Ming Lu, Bo Gao, Xin Qiao, Bei Sun, Dongbo Xue, Weihui Zhang
Pages: 1591-1596
Published online on: 04 March 2013

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Article

The viable Mycobacterium tuberculosis H37Ra strain induces a stronger mouse macrophage response compared to the heat-inactivated H37Rv strain

Zong-Lin He, Fa-Wang Du, Xian-Zhi Du
Pages: 1597-1602
Published online on: 08 March 2013

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Article

High-flux dialysis improves pulmonary ventilation function in uremic patients

Hui Lin, Yong-Gui Wu, Jiang-Huai Zhang, Ming Kan
Pages: 1603-1606
Published online on: 14 March 2013

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Article

Protective effects of Lagerstroemia speciosa on 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in HIT-T15 pancreatic β cells

Jia-Le Song, Xin Zhao, Qiang Wang, Ting Zhang
Pages: 1607-1612
Published online on: 26 March 2013

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Article

Ilex kudingcha C.J. Tseng (Kudingcha) prevents HCl/ethanol‑induced gastric injury in Sprague‑Dawley rats

Xin Zhao, Qiang Wang, Yu Qian, Jia-Le Song
Pages: 1613-1616
Published online on: 28 March 2013

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Article

Mesenchymal stem cells overexpressing integrin-linked kinase attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions

Qing Mao, Cheng-Xi Lin, Xiu-Lin Liang, Jian-Shu Gao, Biao Xu
Pages: 1617-1623
Published online on: 28 February 2013

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Article

Effects of Bauhinia championii (Benth.) Benth. polysaccharides on the proliferation and cell cycle of chondrocytes

Liangliang Cai, Hongzhi Ye, Fangrong Yu, Huiting Li, Jiashou Chen, Xianxiang Liu
Pages: 1624-1630
Published online on: 13 March 2013

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Article

DNA integrity is a critical molecular indicator for the assessment of male infertility

Huda Mossa Omran, Moiz Bakhiet, Mariam Ghloom Dashti
Pages: 1631-1635
Published online on: 21 March 2013

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Article

The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro

Xiaodong Sun, Fang Han, Junling Yi, Ningning Hou, Zhibin Cao
Pages: 1636-1640
Published online on: 28 February 2013

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Article

NS-398 enhances the efficacy of bortezomib against RPMI8226 human multiple myeloma cells

Wenzhong Que, Saiyuan Li, Junmin Chen
Pages: 1641-1645
Published online on: 26 March 2013

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Article

Signaling network of OSW‑1‑induced apoptosis and necroptosis in hepatocellular carcinoma

Jichun Jin, Xinglin Jin, Changshi Qian, Yang Ruan , Hao Jiang
Pages: 1646-1650
Published online on: 13 March 2013

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Article

RNA interference‑mediated inhibition of survivin and VEGF in pancreatic cancer cells in vitro

Jianlin Song, Lipin Cao, Yixiong Li
Pages: 1651-1655
Published online on: 06 March 2013

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Article

The pyrimidine analog FNC inhibits cell proliferation and viral protein synthesis in HTLV‑1‑infected cells

Jinheng Wang, Xia Wang, Cai Gao, Xiangfeng Song, Zhiguo Niu, Zhitao Gao, Zhihai Qin, Junbiao Chang, Hui Wang
Pages: 1656-1660
Published online on: 05 March 2013

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Article

Activation of spinal ERK1/2 contributes to mechanical allodynia in a rat model of postoperative pain

Xu‑Dan Shi, Di Fu, Jun‑Mei Xu, Yan‑Ling Zhang, Ru‑Ping Dai
Pages: 1661-1665
Published online on: 28 February 2013

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Article

Interaction between cAMP, volume‑regulated anion channels and the Na+‑HCO3‑‑cotransporter, NBCe1, in the regulation of nutrient‑ and hypotonicity‑induced insulin release from isolated rat pancreatic islets and tumoral insulin‑producing BRIN‑BD11 cells

Nurdan Bulur, Raphael Crutzen, Willy J. Malaisse, Abdullah Sener, Renaud Beauwens, Philippe Golstein
Pages: 1666-1672
Published online on: 28 February 2013

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Article

Ursolic acid induces apoptosis via Akt/NF-κB signaling suppression in T24 human bladder cancer cells

Long Gai, Na Cai, Lingling Wang, Xiaoyi Xu, Xiangbo Kong
Pages: 1673-1677
Published online on: 11 March 2013

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Article

Overexpression of high mobility group protein B1 correlates with the proliferation and metastasis of lung adenocarcinoma cells

Ke-Kang Sun, Cheng Ji, Xing Li, Lu Zhang, Jun Deng, Ning Zhong, Xiao-Yang Wu
Pages: 1678-1682
Published online on: 06 March 2013

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Article

Effects of edaravone on the expression of β-defensin-2 mRNA in lung tissue of rats with myocardial ischemia reperfusion

Weiwei Zhang, Yongqing Guo, Shuzhen Yu, Jianfeng Wei, Jianmin Jin
Pages: 1683-1687
Published online on: 22 March 2013

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Article

siRNA targeting of PRDX3 enhances cisplatin‑induced apoptosis in ovarian cancer cells through the suppression of the NF‑κB signaling pathway

Jie Duan, Yan Lang, Chengwen Song, Jun Xiong, Yan Wang, Yang Yan
Pages: 1688-1694
Published online on: 14 March 2013

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Article

Transforming growth factor-β1 gene mutations and phenotypes in pediatric patients with Camurati‑Engelmann disease

Chun Wang, Bao-Hong Zhang, Yu-Juan Liu, Yun-Qiu Hu, Jin-Wei He, Zhen-Lin Zhang
Pages: 1695-1699
Published online on: 13 March 2013

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Article

Comparative proteomic analysis of ductal breast carcinoma demonstrates an altered expression of chaperonins and cytoskeletal proteins

Paolo Carcoforo, Blendi Ura, Carlo Mischiati, Monica Squerzanti, Vincenzo Lanzara, Carlo Cervellati, Roberta Calza, Patrizia Polverino De Laureto, Erica Frare, Mattia Portinari, Giordana Feriotto, Serena Lanzara, Enzo Agostinelli, Carlo M. Bergamini
Pages: 1700-1704
Published online on: 15 March 2013

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Article

Effect of histone deacetylase inhibitors on cell apoptosis and expression of the tumor suppressor genes RUNX3 and ARHI in ovarian tumors

Lan Zhang, Peishu Liu, Hua Li, Fuying Xue
Pages: 1705-1709
Published online on: 14 March 2013

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Article

Developmental delay referrals and the roles of Fragile X testing and molecular karyotyping: A New Zealand perspective

Elaine Doherty, Rachel O'Connor, Anna Zhang, Christina Lim, Jennifer M. Love, Fern Ashton, Karen Claxton, Nerine Gregersen, Alice M. George, Donald R. Love
Pages: 1710-1714
Published online on: 20 March 2013

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
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Published online on: 21 November 2025

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Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

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Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

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Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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