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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2013 Volume 7 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Apelin elevates blood pressure in ICR mice with L‑NAME‑induced endothelial dysfunction

Katsumasa Nagano, Junji Ishida, Madoka Unno, Tanomu Matsukura, Akiyoshi Fukamizu
Pages: 1371-1375
Published online on: 15 March 2013

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Article

Expression and biological role of CIP2A in human astrocytoma

Fuxin Yi, Weimin Ni, Weixian Liu, Jinyang Bai, Wenbin Li
Pages: 1376-1380
Published online on: 05 March 2013

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Article Open Access

Clinical significance of keratinocyte growth factor and K-sam gene expression in gastric cancer

Hideki Tani, Noboru Saito, Makio Kobayashi, Shingo Kameoka
Pages: 1381-1386
Published online on: 27 March 2013

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Article

Overexpression of AKT decreases the chemosensitivity of gastric cancer cells to cisplatin in vitro and in vivo

Ling-li Zhang, Jun Zhang, Lei Shen, Xi-ming Xu, Hong-gang Yu
Pages: 1387-1390
Published online on: 28 March 2013

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Article

Combined CT angiography and SPECT myocardial perfusion imaging for the detection of functionally relevant coronary stenoses

Jian‑Ming Li, Rong‑Fang Shi, Li‑Ren Zhang, Ting Li, Zhi Dong
Pages: 1391-1396
Published online on: 04 March 2013

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Article

In vivo dynamic monitoring of the biological behavior of labeled C6 glioma by MRI

Jichun Liao, Rui Xia, Ting Liu, Hua Feng, Hua Ai, Bin Song, Fabao Gao
Pages: 1397-1402
Published online on: 13 March 2013

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Article

Crude extract of Euphorbia formosana inhibits the migration and invasion of DU145 human prostate cancer cells: The role of matrix metalloproteinase-2/9 inhibition via the MAPK signaling pathway

Jiun-Long Yang, Ju-Hwa Lin, Shu-Wen Weng, Jaw-Chyun Chen, Jai-Sing Yang, Sakae Amagaya, Shinji Funayana, W. Gibson Wood, Chao-Lin Kuo, Jing-Gung Chung
Pages: 1403-1408
Published online on: 20 March 2013

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Article

Overexpression of hTERT in potentially malignant colorectal laterally spreading tumors

Jun Li, Xun Cao, Yi Fang, Zhen-Er Liao, Yu-Ying Liu, Bi-Dan Huang, Yu-Jing Han
Pages: 1409-1412
Published online on: 15 March 2013

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Article

Expression and significance of PTEN and miR-92 in hepatocellular carcinoma

Bin Zhao, Yueting Zhu, Kai Cui, Jie Gao, Fachang Yu, Liang Chen, Sheng Li
Pages: 1413-1416
Published online on: 28 March 2013

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Article

Genome‑wide analysis of DNA methylation in rat lungs with lipopolysaccharide‑induced acute lung injury

Xiao‑Qiang Zhang, Chang‑Jun Lv, Xiang‑Yong Liu, Dong Hao, Jing  Qin, Huan‑Huan Tian, Yan Li, Xiao‑Zhi Wang
Pages: 1417-1424
Published online on: 28 March 2013

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Article

Effects of paeonol on intracellular calcium concentration and expression of RUNX3 in LoVo human colon cancer cells

Ming Li, Shi‑Yun Tan, Jun Zhang, Hong‑Xia You
Pages: 1425-1430
Published online on: 14 March 2013

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Article

Temporospatial expression and cellular localization of glutamine synthetase following traumatic spinal cord injury in adult rats

Chunxing Liu, Wenjie Wu, Bin Zhang, Jie Xiang, Jian Zou
Pages: 1431-1436
Published online on: 20 March 2013

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Article

A novel chimeric peptide binds MC3T3‑E1 cells to titanium and enhances their proliferation and differentiation

Dan Wang, Xiaofu Liao, Xu Qin, Wei Shi, Bin Zhou
Pages: 1437-1441
Published online on: 01 March 2013

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Article

Transcriptomic and proteomic analysis of human hepatic stellate cells treated with natural taurine

Jian Liang, Xin Deng, Fa-Sheng Wu, Yan-Fang Tang
Pages: 1442-1452
Published online on: 20 March 2013

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Article

Amygdalin inhibits renal fibrosis in chronic kidney disease

Junqi Guo, Weizheng Wu, Mingxiong Sheng, Shunliang Yang, Jianming Tan
Pages: 1453-1457
Published online on: 22 March 2013

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Article

Distribution of lymphatic tissues and autonomic nerves in supporting ligaments around the cervix uteri

Jianping Zhang, Lanlan Feng, Yi Lu, Dongxia Guo, Tengteng Xi, Xiaochun Wang
Pages: 1458-1464
Published online on: 06 March 2013

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Article

Cardiomyocyte differentiation of perinatally‑derived mesenchymal stem cells

Kuneerat Nartprayut, Yaowalak U‑Pratya, Pakpoom Kheolamai, Sirikul Manochantr, Methichit Chayosumrit, Surapol Issaragrisil, Aungkura Supokawej
Pages: 1465-1469
Published online on: 04 March 2013

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Article

Levels of leptin and IL-6 in lungs and blood are associated with the severity of chronic obstructive pulmonary disease in patients and rat models

Rui Liang, Wei Zhang, Ya-Mei Song
Pages: 1470-1476
Published online on: 15 March 2013

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Article

Overexpression of C10orf116 promotes proliferation, inhibits apoptosis and enhances glucose transport in 3T3-L1 adipocytes

Ling Chen, Xiao-Guang Zhou, Xiao-Yu Zhou, Chun Zhu, Chen-Bo Ji, Chun-Mei Shi, Jie Qiu, Xi-Rong Guo
Pages: 1477-1481
Published online on: 01 March 2013

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Article

Expression of 11β-HSD in steroid-induced avascular necrosis of the femoral head

Lin Wang, Deng-Ke Luo, Zhen-Yu Pan
Pages: 1482-1486
Published online on: 28 March 2013

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Article

Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-α, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro

Yao-Li Chen, Meng-Yi Yan, Su-Yu Chien, Shou-Jen Kuo, Dar‑Ren Chen, Chun-Yuan Cheng, Chin-Cheng Su
Pages: 1487-1493
Published online on: 20 March 2013

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Article

Expression of basigin in the early phase of acute myocardial ischemia in rats

Yun Liu, Wei‑Bo Liang, Lu‑Shun Zhang, Lin‑Bo Gao, Tian‑Yi Chen, Yan‑Yun Wang, Lin Zhang
Pages: 1494-1500
Published online on: 20 March 2013

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Article

Knockdown of autophagy-related gene BECLIN1 promotes cell growth and inhibits apoptosis in the A549 human lung cancer cell line

Wenyu Wang, Hongkun Fan, Yun Zhou, Ping Duan, Guoqiang Zhao, Gang Wu
Pages: 1501-1505
Published online on: 19 March 2013

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Article

microRNA expression profiling in multidrug resistance of the 5‑Fu‑induced SGC‑7901 human gastric cancer cell line

Yan Wang, Xiaodong Gu, Zhenyang Li, Jianbin Xiang, Jianhai Jiang, Zongyou Chen
Pages: 1506-1510
Published online on: 20 March 2013

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Article

Synergistic protective effects of escin and low‑dose glucocorticoids on blood‑retinal barrier breakdown in a rat model of retinal ischemia

Fenglan Zhang, Yuanbin Li, Leiming Zhang, Guoying Mu
Pages: 1511-1515
Published online on: 15 March 2013

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Article

Electroacupuncture ameliorates cognitive impairment through inhibition of NF-κB-mediated neuronal cell apoptosis in cerebral ischemia-reperfusion injured rats

Xiaodong Feng, Shanli Yang, Jiao Liu, Jia Huang, Jun Peng, Jiumao Lin, Jing Tao, Lidian Chen
Pages: 1516-1522
Published online on: 22 March 2013

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Article

Electrical stimulation enhances peripheral nerve regeneration after crush injury in rats

Xu Zhang, Na Xin, Lei Tong, Xiao-Jie Tong
Pages: 1523-1527
Published online on: 26 March 2013

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Article

Effects of different states of oxidative stress on fetal rat alveolar type II epithelial cells in vitro and ROS‑induced changes in Wnt signaling pathway expression

Zhu Li, Fang Fang, Feng Xu
Pages: 1528-1532
Published online on: 20 March 2013

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Article

Effects of matrine on oval cell‑mediated liver regeneration and expression of RBP‑Jκ and HES1

Zhi‑Yun Yang, Li Wang, Yi‑Xin Hou, Xian‑Bo Wang
Pages: 1533-1538
Published online on: 27 March 2013

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Article

The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells

Yu-Ren Liao, Chi-Cheng Lu, Kuang-Chi Lai, Jai-Sing Yang, Sheng‑Chu Kuo, Yen-Fang Wen, Shinji Fushiya, Tian-Shung Wu
Pages: 1539-1544
Published online on: 05 March 2013

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Article

A unique case of female pseudohermaphroditism with 21-hydroxylase deficiency and small supernumerary marker chromosome 7

Walid Al-Achkar, Abdulsamad Wafa, Manar Assaad, Christian Ehlers, Thomas Liehr
Pages: 1545-1548
Published online on: 28 February 2013

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Article

Paired box 2 induces epithelial-mesenchymal transition in normal renal tubular epithelial cells of rats

Li Li, Yubin Wu, Yongchang Yang
Pages: 1549-1554
Published online on: 12 March 2013

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Article

Antitumor activity of bee pollen polysaccharides from Rosa rugosa

Bo Wang, Qiyu Diao, Zhongyu Zhang, Yang Liu, Qipin Gao, Yifa Zhou, Shanshan Li
Pages: 1555-1558
Published online on: 20 March 2013

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Article

The mechanism through which octreotide inhibits hepatic stellate cell activity

Jingjing Wang, Lin Wang, Guanhua Song, Bo Han
Pages: 1559-1564
Published online on: 20 March 2013

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Article

Morroniside promotes bone marrow mesenchymal stem cell proliferation in rats

Naiwu Hu, Shujun Ren, Wei Li, Tao Zhang, Chengbin Zhao
Pages: 1565-1570
Published online on: 28 March 2013

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Article

Alzheimer's phenotypes induced by overexpression of human presenilin 2 mutant proteins stimulate significant changes in key factors of glucose metabolism

Young Ju Lee, Ji Eun Kim, In Sik Hwang, Moon Hwa Kwak, Jae Ho Lee, Young Jin Jung, Beum Soo An, Hyeog Soong Kwon, Byoung Chul Kim, Seon Jong Kim, Joo Man Kim, Dae Youn Hwang
Pages: 1571-1578
Published online on: 28 March 2013

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Article

miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling

Yong Chen, Ying Sun, Longbang Chen, Xingxiang Xu, Xizhi Zhang, Buhai Wang, Lingfeng Min, Wei Liu
Pages: 1579-1584
Published online on: 28 March 2013

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Article

Bigelovii A induces apoptosis of HL‑60 human acute promyelocytic leukaemia cells

Fuqin Guan, Haiting Wang, Yu Shan, Dongmei Zhang, Youyi Zhao, Yu Chen, Qizhi Wang, Ming Wang, Xu Feng
Pages: 1585-1590
Published online on: 01 March 2013

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Article

Differentially expressed kinase genes associated with trypsinogen activation in rat pancreatic acinar cells treated with taurolithocholic acid 3-sulfate

Biao Ma, Lin Wu, Ming Lu, Bo Gao, Xin Qiao, Bei Sun, Dongbo Xue, Weihui Zhang
Pages: 1591-1596
Published online on: 04 March 2013

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Article

The viable Mycobacterium tuberculosis H37Ra strain induces a stronger mouse macrophage response compared to the heat-inactivated H37Rv strain

Zong-Lin He, Fa-Wang Du, Xian-Zhi Du
Pages: 1597-1602
Published online on: 08 March 2013

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Article

High-flux dialysis improves pulmonary ventilation function in uremic patients

Hui Lin, Yong-Gui Wu, Jiang-Huai Zhang, Ming Kan
Pages: 1603-1606
Published online on: 14 March 2013

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Article

Protective effects of Lagerstroemia speciosa on 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in HIT-T15 pancreatic β cells

Jia-Le Song, Xin Zhao, Qiang Wang, Ting Zhang
Pages: 1607-1612
Published online on: 26 March 2013

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Article

Ilex kudingcha C.J. Tseng (Kudingcha) prevents HCl/ethanol‑induced gastric injury in Sprague‑Dawley rats

Xin Zhao, Qiang Wang, Yu Qian, Jia-Le Song
Pages: 1613-1616
Published online on: 28 March 2013

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Article

Mesenchymal stem cells overexpressing integrin-linked kinase attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions

Qing Mao, Cheng-Xi Lin, Xiu-Lin Liang, Jian-Shu Gao, Biao Xu
Pages: 1617-1623
Published online on: 28 February 2013

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Article

Effects of Bauhinia championii (Benth.) Benth. polysaccharides on the proliferation and cell cycle of chondrocytes

Liangliang Cai, Hongzhi Ye, Fangrong Yu, Huiting Li, Jiashou Chen, Xianxiang Liu
Pages: 1624-1630
Published online on: 13 March 2013

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Article

DNA integrity is a critical molecular indicator for the assessment of male infertility

Huda Mossa Omran, Moiz Bakhiet, Mariam Ghloom Dashti
Pages: 1631-1635
Published online on: 21 March 2013

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Article

The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro

Xiaodong Sun, Fang Han, Junling Yi, Ningning Hou, Zhibin Cao
Pages: 1636-1640
Published online on: 28 February 2013

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Article

NS-398 enhances the efficacy of bortezomib against RPMI8226 human multiple myeloma cells

Wenzhong Que, Saiyuan Li, Junmin Chen
Pages: 1641-1645
Published online on: 26 March 2013

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Article

Signaling network of OSW‑1‑induced apoptosis and necroptosis in hepatocellular carcinoma

Jichun Jin, Xinglin Jin, Changshi Qian, Yang Ruan , Hao Jiang
Pages: 1646-1650
Published online on: 13 March 2013

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Article

RNA interference‑mediated inhibition of survivin and VEGF in pancreatic cancer cells in vitro

Jianlin Song, Lipin Cao, Yixiong Li
Pages: 1651-1655
Published online on: 06 March 2013

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Article

The pyrimidine analog FNC inhibits cell proliferation and viral protein synthesis in HTLV‑1‑infected cells

Jinheng Wang, Xia Wang, Cai Gao, Xiangfeng Song, Zhiguo Niu, Zhitao Gao, Zhihai Qin, Junbiao Chang, Hui Wang
Pages: 1656-1660
Published online on: 05 March 2013

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Article

Activation of spinal ERK1/2 contributes to mechanical allodynia in a rat model of postoperative pain

Xu‑Dan Shi, Di Fu, Jun‑Mei Xu, Yan‑Ling Zhang, Ru‑Ping Dai
Pages: 1661-1665
Published online on: 28 February 2013

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Article

Interaction between cAMP, volume‑regulated anion channels and the Na+‑HCO3‑‑cotransporter, NBCe1, in the regulation of nutrient‑ and hypotonicity‑induced insulin release from isolated rat pancreatic islets and tumoral insulin‑producing BRIN‑BD11 cells

Nurdan Bulur, Raphael Crutzen, Willy J. Malaisse, Abdullah Sener, Renaud Beauwens, Philippe Golstein
Pages: 1666-1672
Published online on: 28 February 2013

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Article

Ursolic acid induces apoptosis via Akt/NF-κB signaling suppression in T24 human bladder cancer cells

Long Gai, Na Cai, Lingling Wang, Xiaoyi Xu, Xiangbo Kong
Pages: 1673-1677
Published online on: 11 March 2013

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Article

Overexpression of high mobility group protein B1 correlates with the proliferation and metastasis of lung adenocarcinoma cells

Ke-Kang Sun, Cheng Ji, Xing Li, Lu Zhang, Jun Deng, Ning Zhong, Xiao-Yang Wu
Pages: 1678-1682
Published online on: 06 March 2013

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Article

Effects of edaravone on the expression of β-defensin-2 mRNA in lung tissue of rats with myocardial ischemia reperfusion

Weiwei Zhang, Yongqing Guo, Shuzhen Yu, Jianfeng Wei, Jianmin Jin
Pages: 1683-1687
Published online on: 22 March 2013

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Article

siRNA targeting of PRDX3 enhances cisplatin‑induced apoptosis in ovarian cancer cells through the suppression of the NF‑κB signaling pathway

Jie Duan, Yan Lang, Chengwen Song, Jun Xiong, Yan Wang, Yang Yan
Pages: 1688-1694
Published online on: 14 March 2013

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Article

Transforming growth factor-β1 gene mutations and phenotypes in pediatric patients with Camurati‑Engelmann disease

Chun Wang, Bao-Hong Zhang, Yu-Juan Liu, Yun-Qiu Hu, Jin-Wei He, Zhen-Lin Zhang
Pages: 1695-1699
Published online on: 13 March 2013

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Article

Comparative proteomic analysis of ductal breast carcinoma demonstrates an altered expression of chaperonins and cytoskeletal proteins

Paolo Carcoforo, Blendi Ura, Carlo Mischiati, Monica Squerzanti, Vincenzo Lanzara, Carlo Cervellati, Roberta Calza, Patrizia Polverino De Laureto, Erica Frare, Mattia Portinari, Giordana Feriotto, Serena Lanzara, Enzo Agostinelli, Carlo M. Bergamini
Pages: 1700-1704
Published online on: 15 March 2013

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Article

Effect of histone deacetylase inhibitors on cell apoptosis and expression of the tumor suppressor genes RUNX3 and ARHI in ovarian tumors

Lan Zhang, Peishu Liu, Hua Li, Fuying Xue
Pages: 1705-1709
Published online on: 14 March 2013

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Article

Developmental delay referrals and the roles of Fragile X testing and molecular karyotyping: A New Zealand perspective

Elaine Doherty, Rachel O'Connor, Anna Zhang, Christina Lim, Jennifer M. Love, Fern Ashton, Karen Claxton, Nerine Gregersen, Alice M. George, Donald R. Love
Pages: 1710-1714
Published online on: 20 March 2013

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Review Open Access

Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
Published online on: 03 September 2026

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Review Open Access

From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
Published online on: 03 September 2026

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Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
Published online on: 02 September 2026

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Correction Open Access

[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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Article Open Access

POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
Published online on: 24 August 2026

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Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
Published online on: 21 August 2026

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Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
Published online on: 20 August 2026

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Article Open Access

Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Review Open Access

Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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Article Open Access

6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Article Open Access

Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Article Open Access

Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Review

Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Article Open Access

Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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Article Open Access

STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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November-2026 Volume 34 Issue 5

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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