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Article

Expression of basigin in the early phase of acute myocardial ischemia in rats

  • Authors:
    • Yun Liu
    • Wei‑Bo Liang
    • Lu‑Shun Zhang
    • Lin‑Bo Gao
    • Tian‑Yi Chen
    • Yan‑Yun Wang
    • Lin Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of Immunology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 1494-1500
    |
    Published online on: March 20, 2013
       https://doi.org/10.3892/mmr.2013.1387
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Abstract

Basigin may be involved in cardiovascular disease. In our previous study, suppression subtractive hybridization results indicated that basigin may be associated with the early phase of acute myocardial ischemia (AMI) within 1 h. However, little is known regarding the expression of basigin in the early phase of AMI. The aim of the present study was to evaluate the temporal and spatial expression patterns of basigin mRNA and protein levels in AMI in rats. We constructed an AMI model in rats that received left anterior descending coronary artery ligation for 0, 15, 30, 60, 120 or 240 min. Real‑time quantitative PCR and in situ hybridization (ISH) were conducted to reveal the basigin mRNA levels in the early ischemic myocardium (EIM) and non‑ischemic myocardium (NIM). The expression levels of basigin protein were detected using western blot analysis and immunohistochemistry. The expression levels of basigin mRNA and protein significantly changed in the EIM as early as 30 min from ischemia, and the changes continued to be present throughout the ischemic period (P<0.05). The expression levels of basigin mRNA were significantly reduced, whilst those of the protein underwent a significant ~2-fold increase in the EIM. However, there were no significant differences in the basigin mRNA or protein expression levels from 0‑240 min in the NIM (P>0.05). We failed to detect a signal for basigin mRNA in the myocardium by ISH. Our findings indicated that basigin may be involved in acute myocardial ischemia following continual ischemia for >30 min.
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1 

Xu XH, Chen JG and Zhu JZ: Primary study of vascular endothelial growth factor immunohistochemical staining in the diagnosis of early acute myocardial ischemia. Forensic Sci Int. 118:11–14. 2001. View Article : Google Scholar : PubMed/NCBI

2 

Ostadal B, Netuka I, Maly J, Besik J and Ostadalova I: Gender differences in cardiac ischemic injury and protection - experimental aspects. Exp Biol Med (Maywood). 234:1011–1019. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Mehta D, Curwin J, Gomes JA and Fuster V: Sudden death in coronary artery disease: acute ischemia versus myocardial substrate. Circulation. 96:3215–3223. 1997. View Article : Google Scholar : PubMed/NCBI

4 

Campobasso CP, Dell'Erba AS, Addante A, Zotti F, Marzullo A and Colonna MF: Sudden cardiac death and myocardial ischemia indicators: a comparative study of four immunohistochemical markers. Am J Forensic Med Pathol. 29:154–161. 2008. View Article : Google Scholar : PubMed/NCBI

5 

Vargas SO, Sampson BA and Schoen FJ: Pathologic detection of early myocardial infarction: a critical review of the evolution and usefulness of modern techniques. Mod Pathol. 12:635–645. 1999.PubMed/NCBI

6 

Bardales RH, Hailey LS, Xie SS, Schaefer RF and Hsu SM: In situ apoptosis assay for the detection of early acute myocardial infarction. Am J Pathol. 149:821–829. 1996.PubMed/NCBI

7 

Xiaohong Z, Xiaorui C, Jun H and Qisheng Q: The contrast of immunohistochemical studies of myocardial fibrinogen and myoglobin in early myocardial ischemia in rats. Leg Med (Tokyo). 4:47–51. 2002. View Article : Google Scholar : PubMed/NCBI

8 

Lie JT, Holley KE, Kampa WR and Titus JL: New histochemical method for morphologic diagnosis of early stages of myocardial ischemia. Mayo Clin Proc. 46:319–327. 1971.PubMed/NCBI

9 

Liu Y, Gao LB, Liang WB, Pan XM, Wang YY, Xue H, Chen TY, Zhang LS, Zhu Y and Zhang L: The expression of Basigin mRNA in early ischemic myocardium and non-ischemic myocardium. Sichuan Da Xue Xue Bao Yi Xue Ban. 41:81–84. 2010.(In Chinese).

10 

Biswas C, Zhang Y, DeCastro R, et al: The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res. 55:434–439. 1995.PubMed/NCBI

11 

Biswas C: Tumor cell stimulation of collagenase production by fibroblasts. Biochem Biophys Res Commun. 109:1026–1034. 1982. View Article : Google Scholar : PubMed/NCBI

12 

Caudroy S, Polette M, Nawrocki-Raby B, et al: EMMPRIN-mediated MMP regulation in tumor and endothelial cells. Clin Exp Metastasis. 19:697–702. 2002. View Article : Google Scholar : PubMed/NCBI

13 

Spinale FG, Coker ML, Heung LJ, et al: A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure. Circulation. 102:1944–1949. 2000. View Article : Google Scholar

14 

Siwik DA, Kuster GM, Brahmbhatt JV, et al: EMMPRIN mediates beta-adrenergic receptor-stimulated matrix metalloproteinase activity in cardiac myocytes. J Mol Cell Cardiol. 44:210–217. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Nie R, Xie S, Du B, Liu X, Deng B and Wang J: Extracellular matrix metalloproteinase inducer (EMMPRIN) is increased in human left ventricle after acute myocardial infarction. Arch Med Res. 40:605–611. 2009. View Article : Google Scholar : PubMed/NCBI

16 

Seizer P, Ochmann C, Schönberger T, et al: Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arterioscler Thromb Vasc Biol. 31:1377–1386. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Yoon YW, Kwon HM, Hwang KC, et al: Upstream regulation of matrix metalloproteinase by EMMPRIN; extracellular matrix metalloproteinase inducer in advanced atherosclerotic plaque. Atherosclerosis. 180:37–44. 2005. View Article : Google Scholar

18 

Spinale FG, Coker ML, Bond BR and Zellner JL: Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target. Cardiovasc Res. 46:225–238. 2000. View Article : Google Scholar : PubMed/NCBI

19 

Zhang G, Zhou B, Zheng Y, et al: Time course proteomic profile of rat acute myocardial infarction by SELDI-TOF MS analysis. Int J Cardiol. 131:225–233. 2009. View Article : Google Scholar : PubMed/NCBI

20 

Ushizawa K, Takahashi T, Hosoe M, et al: Gene expression profiles of novel caprine placental prolactin-related proteins similar to bovine placental prolactin-related proteins. BMC Dev Biol. 7:162007. View Article : Google Scholar : PubMed/NCBI

21 

Calmels TP and Mazurais D: In situ hybridization: a technique to study localization of cardiac gene expression. Methods Mol Biol. 366:159–180. 2007. View Article : Google Scholar : PubMed/NCBI

22 

Guo H, Majmudar G, Jensen TC, Biswas C, Toole BP and Gordon MK: Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases. Gene. 220:99–108. 1998. View Article : Google Scholar : PubMed/NCBI

23 

Zheng HC, Wang W, Xu XY, et al: Up-regulated EMMPRIN/CD147 protein expression might play a role in colorectal carcinogenesis and its subsequent progression without an alteration of its glycosylation and mRNA level. J Cancer Res Clin Oncol. 137:585–596. 2011. View Article : Google Scholar

24 

Suzuki S, Sato M, Senoo H and Ishikawa K: Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP. Exp Cell Res. 293:259–266. 2004. View Article : Google Scholar : PubMed/NCBI

25 

Hanata K, Yamaguchi N, Yoshikawa K, et al: Soluble EMMPRIN (extra-cellular matrix metalloproteinase inducer) stimulates the migration of HEp-2 human laryngeal carcinoma cells, accompanied by increased MMP-2 production in fibroblasts. Arch Histol Cytol. 70:267–277. 2007. View Article : Google Scholar

26 

Kanekura T, Chen X and Kanzaki T: Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer. 99:520–528. 2002. View Article : Google Scholar : PubMed/NCBI

27 

Sommers HM and Jennings RB: Experimental acute myocardial infarction; histologic and histochemical studies of early myocardial infarcts induced by temporary or permanent occlusion of a coronary artery. Lab Invest. 13:1491–1503. 1964.

28 

Seko Y, Fujimura T, Taka H, Mineki R, Murayama K and Nagai R: Hypoxia followed by reoxygenation induces secretion of cyclophilin A from cultured rat cardiac myocytes. Biochem Biophys Res Commun. 317:162–168. 2004. View Article : Google Scholar : PubMed/NCBI

29 

Foda HD, Rollo EE, Drews M, et al: Ventilator-induced lung injury upregulates and activates gelatinases and EMMPRIN: attenuation by the synthetic matrix metalloproteinase inhibitor, Prinomastat (AG3340). Am J Respir Cell Mol Biol. 25:717–724. 2001. View Article : Google Scholar

30 

Schmidt R, Redecke V, Breitfeld Y, et al: EMMPRIN (CD 147) is a central activator of extracellular matrix degradation by Chlamydia pneumoniae-infected monocytes. Implications for plaque rupture. Thromb Haemost. 95:151–158. 2006.PubMed/NCBI

31 

May AE, Schmidt R, Bülbül BO, et al: Plasminogen and matrix metalloproteinase activation by enzymatically modified low density lipoproteins in monocytes and smooth muscle cells. Thromb Haemost. 93:710–715. 2005.PubMed/NCBI

32 

Schmidt R, Bültmann A, Fischel S, et al: Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes. Circ Res. 102:302–309. 2008. View Article : Google Scholar

33 

Zhang F, Vannucci SJ, Philp NJ and Simpson IA: Monocarboxylate transporter expression in the spontaneous hypertensive rat: effect of stroke. J Neurosci Res. 79:139–145. 2005. View Article : Google Scholar : PubMed/NCBI

34 

Han M, Trotta P, Coleman C and Linask KK: MCT-4, A511/Basigin and EF5 expression patterns during early chick cardiomyogenesis indicate cardiac cell differentiation occurs in a hypoxic environment. Dev Dyn. 235:124–131. 2006. View Article : Google Scholar

35 

Kirk P, Wilson MC, Heddle C, Brown MH, Barclay AN and Halestrap AP: CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J. 19:3896–3904. 2000. View Article : Google Scholar : PubMed/NCBI

36 

Gabison EE, Mourah S, Steinfels E, et al: Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: role in epithelio-stromal interactions and matrix metalloproteinase induction. Am J Pathol. 166:209–219. 2005. View Article : Google Scholar

37 

Zavadzkas JA, Plyler RA, Bouges S, et al: Cardiac-restricted overexpression of extracellular matrix metalloproteinase inducer causes myocardial remodeling and dysfunction in aging mice. Am J Physiol Heart Circ Physiol. 295:H1394–H1402. 2008. View Article : Google Scholar

38 

Burggraf D, Liebetrau M, Martens HK, et al: Matrix metalloproteinase induction by EMMPRIN in experimental focal cerebral ischemia. Eur J Neurosci. 22:273–277. 2005. View Article : Google Scholar : PubMed/NCBI

39 

Betsuyaku T, Kadomatsu K, Griffin GL, Muramatsu T and Senior RM: Increased basigin in bleomycin-induced lung injury. Am J Respir Cell Mol Biol. 28:600–606. 2003. View Article : Google Scholar : PubMed/NCBI

40 

Shimada M, Yamabe H, Osawa H, et al: Extracellular matrix metalloproteinase inducer is expressed in the proximal tubular epithelial cells of the human kidney. Nephrology (Carlton). 14:171–178. 2009. View Article : Google Scholar : PubMed/NCBI

41 

Liang L, Major T and Bocan T: Characterization of the promoter of human extracellular matrix metalloproteinase inducer (EMMPRIN). Gene. 282:75–86. 2002. View Article : Google Scholar : PubMed/NCBI

42 

Ruiz S, Castro-Castro A and Bustelo XR: CD147 inhibits the nuclear factor of activated T-cells by impairing Vav1 and Rac1 downstream signaling. J Biol Chem. 283:5554–5566. 2008. View Article : Google Scholar : PubMed/NCBI

43 

Joghetaei N, Akhyari P, Rauch BH, et al: Extracellular matrix metalloproteinase inducer (CD147) and membrane type 1-matrix metalloproteinase are expressed on tissue macrophages in calcific aortic stenosis and induce transmigration in an artificial valve model. J Thorac Cardiovasc Surg. 142:191–198. 2010. View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Liu Y, Liang WB, Zhang LS, Gao LB, Chen TY, Wang YY and Zhang L: Expression of basigin in the early phase of acute myocardial ischemia in rats. Mol Med Rep 7: 1494-1500, 2013.
APA
Liu, Y., Liang, W., Zhang, L., Gao, L., Chen, T., Wang, Y., & Zhang, L. (2013). Expression of basigin in the early phase of acute myocardial ischemia in rats. Molecular Medicine Reports, 7, 1494-1500. https://doi.org/10.3892/mmr.2013.1387
MLA
Liu, Y., Liang, W., Zhang, L., Gao, L., Chen, T., Wang, Y., Zhang, L."Expression of basigin in the early phase of acute myocardial ischemia in rats". Molecular Medicine Reports 7.5 (2013): 1494-1500.
Chicago
Liu, Y., Liang, W., Zhang, L., Gao, L., Chen, T., Wang, Y., Zhang, L."Expression of basigin in the early phase of acute myocardial ischemia in rats". Molecular Medicine Reports 7, no. 5 (2013): 1494-1500. https://doi.org/10.3892/mmr.2013.1387
Copy and paste a formatted citation
x
Spandidos Publications style
Liu Y, Liang WB, Zhang LS, Gao LB, Chen TY, Wang YY and Zhang L: Expression of basigin in the early phase of acute myocardial ischemia in rats. Mol Med Rep 7: 1494-1500, 2013.
APA
Liu, Y., Liang, W., Zhang, L., Gao, L., Chen, T., Wang, Y., & Zhang, L. (2013). Expression of basigin in the early phase of acute myocardial ischemia in rats. Molecular Medicine Reports, 7, 1494-1500. https://doi.org/10.3892/mmr.2013.1387
MLA
Liu, Y., Liang, W., Zhang, L., Gao, L., Chen, T., Wang, Y., Zhang, L."Expression of basigin in the early phase of acute myocardial ischemia in rats". Molecular Medicine Reports 7.5 (2013): 1494-1500.
Chicago
Liu, Y., Liang, W., Zhang, L., Gao, L., Chen, T., Wang, Y., Zhang, L."Expression of basigin in the early phase of acute myocardial ischemia in rats". Molecular Medicine Reports 7, no. 5 (2013): 1494-1500. https://doi.org/10.3892/mmr.2013.1387
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