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Article

MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer

Retraction in: /10.3892/mmr.2023.12944
  • Authors:
    • Deyao Wu
    • Ping Huang
    • Linmao Wang
    • Yunfeng Zhou
    • Huixing Pan
    • Ping Qu
  • View Affiliations / Copyright

    Affiliations: Department of Urology, The Fourth Affiliated Hospital of Nantong Medical College, Yancheng City No. 1 People's Hospital, Yancheng, Jiangsu 224001, P.R. China, Department of Thoracic Surgery, The Fourth Affiliated Hospital of Nantong Medical College, Yancheng City No. 1 People's Hospital, Yancheng, Jiangsu 224001, P.R. China
  • Pages: 626-630
    |
    Published online on: May 31, 2013
       https://doi.org/10.3892/mmr.2013.1501
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Abstract

MicroRN-143 (miR‑143) has been previously reported to be downregulated in specific types of cancer, including colorectal, bladder, oral squamous cell, pituitary, cervical, nasopharyngeal, lymphoma and prostate cancer. In the present study, the effects of miR-143 on prostate cancer cell migration and invasion were examined. Following transfection with miR-143, miR-143 expression, cell migration and invasion assays, luciferase assay and western blot analysis were conducted in prostate cancer cell lines. The results indicated that miR-143 inhibits cell migration and invasion in DU145 and PC-3 cells. In addition, to the best of our knowledge, miR-143 was reported for the first time to directly target matrix metalloproteinase 13 (MMP-13) in prostate cancer. The results of the present study demonstrated that miR-143 suppresses cell migration and invasion by targeting MMP-13 in prostate cancer cell lines. These results indicated that miR-143 may be suitable for the development of novel molecular markers and therapeutic approaches to inhibit metastasis in prostate cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Wu D, Huang P, Wang L, Zhou Y, Pan H and Qu P: MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944. Mol Med Rep 8: 626-630, 2013.
APA
Wu, D., Huang, P., Wang, L., Zhou, Y., Pan, H., & Qu, P. (2013). MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944. Molecular Medicine Reports, 8, 626-630. https://doi.org/10.3892/mmr.2013.1501
MLA
Wu, D., Huang, P., Wang, L., Zhou, Y., Pan, H., Qu, P."MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944". Molecular Medicine Reports 8.2 (2013): 626-630.
Chicago
Wu, D., Huang, P., Wang, L., Zhou, Y., Pan, H., Qu, P."MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944". Molecular Medicine Reports 8, no. 2 (2013): 626-630. https://doi.org/10.3892/mmr.2013.1501
Copy and paste a formatted citation
x
Spandidos Publications style
Wu D, Huang P, Wang L, Zhou Y, Pan H and Qu P: MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944. Mol Med Rep 8: 626-630, 2013.
APA
Wu, D., Huang, P., Wang, L., Zhou, Y., Pan, H., & Qu, P. (2013). MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944. Molecular Medicine Reports, 8, 626-630. https://doi.org/10.3892/mmr.2013.1501
MLA
Wu, D., Huang, P., Wang, L., Zhou, Y., Pan, H., Qu, P."MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944". Molecular Medicine Reports 8.2 (2013): 626-630.
Chicago
Wu, D., Huang, P., Wang, L., Zhou, Y., Pan, H., Qu, P."MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944". Molecular Medicine Reports 8, no. 2 (2013): 626-630. https://doi.org/10.3892/mmr.2013.1501
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