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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2013 Volume 8 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Potassium ion channels in retinal ganglion cells (Review)

Yi‑Sheng Zhong, Jing Wang, Wang‑Min Liu, Yi‑Hua Zhu
Pages: 311-319
Published online on: 04 June 2013

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Article Open Access

Ultrasound‑targeted microbubble destruction enhances gene transduction of adeno-associated virus in a less-permissive cell type, NIH/3T3

Lifang Jin, Fan Li, Huiping Wang, Yunhua Li, Fang Wei, Lianfang Du
Pages: 320-326
Published online on: 27 June 2013

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Article

Treadmill exercise ameliorates motor disturbance through inhibition of apoptosis in the cerebellum of valproic acid-induced autistic rat pups

Ji-Eun Kim, Mal-Soon Shin, Tae-Beom Seo, Eun-Sang Ji, Seong-Soo Baek, Sam-Jun Lee, Joon-Ki Park, Chang-Ju Kim
Pages: 327-334
Published online on: 12 June 2013

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Article

Concentration of tissue angiotensin II increases with severity of experimental pancreatitis

Hiroyuki Furukawa, Atsushi Shinmura, Hidehiro Tajima, Tomoya Tsukada, Shin‑Ichi Nakanuma, Koichi Okamoto, Seisho Sakai, Isamu Makino, Keishi Nakamura, Hironori Hayashi, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Tomoharu Miyashita, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tetsuo Ohta, Tomohiko Wakayama, Shoichi Iseki
Pages: 335-338
Published online on: 06 June 2013

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Article

Identification and analysis of microRNAs in the left ventricular myocardium of two-kidney one-clip hypertensive rats

Gang Sun, Hai Hu, Xuyang Tian, Jianwei Yue, Hui Yu, Xiaomin Yang, Zhanli Wang
Pages: 339-344
Published online on: 25 June 2013

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Article

miR-124 inhibits the growth of glioblastoma through the downregulation of SOS1

Zhonghua Lv, Lizhuang Yang
Pages: 345-349
Published online on: 28 June 2013

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Article

cDNA microarray profiling of rat cholangiocarcinoma induced by thioacetamide

Chun‑Nan Yeh, Wen‑Hui Weng, Govinda Lenka, Lee‑Cheng Tsao, Kun‑Chun Chiang, See‑Tong Pang, Tsung‑Wen Chen, Yi‑Yin Jan, Miin‑Fu Chen
Pages: 350-360
Published online on: 10 June 2013

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Article

Cathepsin B inhibition attenuates cardiac dysfunction and remodeling following myocardial infarction by inhibiting the NLRP3 pathway Retraction in /10.3892/mmr.2017.7551

Aiguo Liu, Xuan Gao, Qingbin Zhang, Lianqun Cui
Pages: 361-366
Published online on: 04 June 2013

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Article

Cytotoxic role of advanced glycation end-products in PC12 cells treated with β‑amyloid peptide

Fu‑Ling Yan, Guo‑Ling Han, Guan‑Jin Wu
Pages: 367-372
Published online on: 25 June 2013

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Article

TOFA suppresses ovarian cancer cell growth in vitro and in vivo

Shu Li, Lihua Qiu, Buchu Wu, Haoran Shen, Jing Zhu, Liang Zhou, Liying Gu, Wen Di
Pages: 373-378
Published online on: 31 May 2013

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Article

miR‑203 regulates the proliferation, apoptosis and cell cycle progression of pancreatic cancer cells by targeting Survivin

Dong Xu, Qingguang Wang, Yong An, Lijian Xu
Pages: 379-384
Published online on: 31 May 2013

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Article

Rosuvastatin prevents pressure overload‑induced myocardial hypertrophy via inactivation of the Akt, ERK1/2 and GATA4 signaling pathways in rats

Xue Xu, Lei Zhang, Jiangjiu Liang
Pages: 385-392
Published online on: 25 June 2013

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Article

Swimming exercise alleviates the symptoms of attention-deficit hyperactivity disorder in spontaneous hypertensive rats

Il-Gyu Ko, Sung-Eun Kim, Tae-Woon Kim, Eun-Sang Ji, Mal-Soon Shin, Chang-Ju Kim, Min-Ha Hong, Geon Ho Bahn
Pages: 393-400
Published online on: 19 June 2013

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Article

Time-course analysis of counts and degranulation of mast cells during early intestinal ischemia-reperfusion injury in mice

Mian Ge, Xiaoliang Gan, Dezhao Liu, Wenhua Zhang, Wanling Gao, Pinjie Huang, Ziqing Hei
Pages: 401-406
Published online on: 18 June 2013

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Article

MiRNA-146a regulates the maturation and differentiation of vascular smooth muscle cells by targeting NF-κB expression

Shaohong Dong, Wei Xiong, Jianhui Yuan, Jianghua Li, Jianjun Liu, Xinyun Xu
Pages: 407-412
Published online on: 20 June 2013

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Article

HPV16 infection regulates RASSF1A transcription mediated by p53

Yueshan Lei, Chengjun Hu, Hongxin Xu, Yihao Tian
Pages: 413-418
Published online on: 17 June 2013

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Article

In vitro and in vivo effects of short hairpin RNA targeting integrin-linked kinase in prostate cancer cells

Yeqing Yuan, Yunbei Xiao, Qing Li, Zhenhua Liu, Xiaowei Zhang, Caipeng Qin, Jing Xie, Xiaofeng Wang, Tao Xu
Pages: 419-424
Published online on: 19 June 2013

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Article

Downregulation of T‑cell lymphoma invasion and metastasis‑inducing factor 1 induces cytoskeletal rearrangement and inhibits the invasive capacity of gastric cancer cells

Jin-Ming Zhu, Pei-Wu Yu
Pages: 425-433
Published online on: 07 June 2013

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Article

A new selective vascular endothelial growth factor receptor 2 inhibitor ablates disease in a mouse model of psoriasis

Heng-Xiu Yan, Yong Wang, Xiao-Nong Yang, Li-Xin Fu, Dong-Mei Tang
Pages: 434-438
Published online on: 31 May 2013

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Article

Oxymatrine ameliorates non-alcoholic fatty liver disease in rats through peroxisome proliferator-activated receptor-α activation

Lijuan Shi, Lei Shi, Hefang Zhang, Zhijuan Hu, Chao Wang, Donghui Zhang, Guangyao Song
Pages: 439-445
Published online on: 06 June 2013

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Article

Evaluation of the usefulness of colonoscopy with mucosal biopsies in the follow-up of TNBS-induced colitis in rats

Magdy El-Salhy, Ingvild Haukaas Wendelbo, Doris Gundersen, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 446-450
Published online on: 17 June 2013

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Article

Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease

Magdy El‑Salhy, Ingvild Wendelbo, Doris Gundersen
Pages: 451-455
Published online on: 14 June 2013

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Article

Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma

Junko Hamamoto, Kenzo Soejima, Satoshi Yoda, Katsuhiko Naoki, Sohei Nakayama, Ryosuke Satomi, Hideki Terai, Shinnosuke Ikemura, Takashi Sato, Hiroyuki Yasuda, Yuichiro Hayashi, Michiie Sakamoto, Toru Takebayashi, Tomoko Betsuyaku
Pages: 456-462
Published online on: 11 June 2013

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Article

Expression profiling of lncRNAs in C3H10T1/2 mesenchymal stem cells undergoing early osteoblast differentiation

Changqing Zuo, Zonggui Wang, Hanyun Lu, Zhong Dai, Xinguang Liu, Liao Cui
Pages: 463-467
Published online on: 21 June 2013

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Article

Combination of negative pressure wound therapy with open bone grafting for bone and soft tissue defects

Kai Deng, Ai-Xi Yu, Cheng-Yan Xia, Zong-Huan Li, Wei-Yang Wang
Pages: 468-472
Published online on: 20 June 2013

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Article

Immunocytochemistry of GLUT2, uptake of fluorescent desnitroso-streptozotocin analogs and phosphorylation of D-glucose in INS-1E cells

Myrna Virreira, Iuliana Popescu, Celine Gillet, Ying Zhang, Yevgeniy Leshch, Julian Thimm, Joachim Thiem, Willy J. Malaisse, Abdullah Sener
Pages: 473-479
Published online on: 27 June 2013

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Article

Mechanistic investigation of immunosuppression in patients with condyloma acuminata

Yu-Jie Shi, Jian Yang, Wenlin Yang
Pages: 480-486
Published online on: 06 June 2013

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Article

Mutations in the STAT1‑interacting domain of the hepatitis C virus core protein modulate the response to antiviral therapy

Sadia Anjum, Muhammad Sohail Afzal, Tahir Ahmad, Baber Aslam, Yasir Waheed, Talha Shafi, Ishtiaq Qadri
Pages: 487-492
Published online on: 25 June 2013

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Article

Lentiviral-mediated p38 MAPK RNAi attenuates aldosterone-induced myocyte apoptosis

Yan Zhou, Yuanhong Liang, Jie Wei, Jing Chen, Qizhu Tang
Pages: 493-498
Published online on: 21 June 2013

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Article

Association between coronary artery calcium score and carotid atherosclerotic disease

Qian Zhao, Xinhuai Wu, Jianming Cai, Xihai Zhao, Shaohong Zhao, Li Yang, Zulong Cai
Pages: 499-504
Published online on: 13 June 2013

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Article

Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma

Xiaolong Yang, Ning Huang
Pages: 505-510
Published online on: 31 May 2013

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Article

Recombinant human decorin upregulates p57KIP2 expression in HepG2 hepatoma cell lines

Abdu Selim Hamid, Jinran Li, Yali Wang, Xiaodong Wu, Hassan Abdellah Ahmed Ali, Zhenwu Du, Lihua Bo, Yucheng Zhang, Guizhen Zhang
Pages: 511-516
Published online on: 06 June 2013

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Article

Monoclonal antibody preparation of Golgi phosphoprotein 2 and preliminary application in the early diagnosis of hepatocellular carcinoma

Qiang Ju, Yanjie Zhao, Yanhong Liu, Guohua Zhou, Feng Li, Pingli Xie, Yuehui Li, Guan-Cheng Li
Pages: 517-522
Published online on: 31 May 2013

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Article

MicroRNA‑1 inhibits the proliferation of chinese sika deer‑derived cartilage cells by binding to the 3'-untranslated region of IGF‑1

Wei Hu, Xingyu Meng, Tiancheng Lu, Lei Wu, Ting Li, Mu Li, Yuhua Tian
Pages: 523-528
Published online on: 10 June 2013

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Article

Analysis of a novel protein in human colorectal adenocarcinoma

Kaicheng Wang, Yao Chen
Pages: 529-534
Published online on: 14 June 2013

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Article

Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation

Isoko Kuriyama, Yuki Nakajima, Hiroshi Nishida, Tetsuya Konishi, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina
Pages: 535-542
Published online on: 25 June 2013

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Article

Neuroprotectin D1 attenuates brain damage induced by transient middle cerebral artery occlusion in rats through TRPC6/CREB pathways

Chengye Yao, Jiancheng Zhang, Fang Chen, Yun Lin
Pages: 543-550
Published online on: 25 June 2013

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Article

Arazyme inhibits cytokine expression and upregulates skin barrier protein expression

In Sik Kim, Mi Jin Kim, Dong‑Ha Shin, Kwang‑Hee Son, Ho‑Yong Park, Ji‑Sook Lee
Pages: 551-556
Published online on: 13 June 2013

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Article

The effect of MAPK inhibitors and ROS modulators on cell growth and death of H2O2‑treated HeLa cells

Woo Hyun Park
Pages: 557-564
Published online on: 25 June 2013

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Article

Acid‑induced cell injury and death in lung epithelial cells is associated with the activation of mitogen‑activated protein kinases

Qiuhua Chen, Yingzi Huang, Yi Yang, Haibo Qiu
Pages: 565-570
Published online on: 20 June 2013

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Article

Expansion of decidual CD45RO+ T cells with high expression of CEACAM1 in the early stage of pregnancy

Qi Xie, Qing-Jie Wang, Yun Zhang, Bei-Hua Kong, Bai-Hua Dong, Xun Qu
Pages: 571-578
Published online on: 25 June 2013

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Article

Serum osteopontin concentration is decreased by exercise-induced fat loss but is not correlated with body fat percentage in obese humans

Jeong Soon You, Hye-In Ji, Kyung Ja Chang, Myung Chul Yoo, Hyung-In Yang, In-Kyung Jeong, Kyoung Soo Kim
Pages: 579-584
Published online on: 13 June 2013

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Article

Gastrodin ameliorates Parkinson's disease by downregulating connexin 43

Yu Wang, Zhe Wu, Xu Liu, Qunying Fu
Pages: 585-590
Published online on: 19 June 2013

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Article

Staphylococcal enterotoxin B and α‑toxin induce the apoptosis of ECV304 cells via similar mechanisms

Feng‑Ling Yu, Ting‑Ting Liu, Xiang Zhu, Weng‑Xuan Yang, Tao Zhang, Na Lin, Yong Liu, Cong‑Sen Liu, Jiu Jiang, Jun‑Chang Guan
Pages: 591-596
Published online on: 25 June 2013

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Article

Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cells

Jinfeng Wu, Fuguo Zuo, Juan Du, Pok Fai Wong, Haihong Qin, Jinhua Xu
Pages: 597-602
Published online on: 26 June 2013

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Article

Activation of the p38 MAPK/NF-κB pathway contributes to doxorubicin-induced inflammation and cytotoxicity in H9c2 cardiac cells

Run-Min Guo, Wen-Ming Xu, Jian-Cong Lin, Li-Qiu Mo, Xiao-Xiao Hua, Pei-Xi Chen, Keng Wu, Dong-Dan Zheng, Jian-Qiang Feng
Pages: 603-608
Published online on: 26 June 2013

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Article

Effect of multivitamins on plasma homocysteine in patients with the 5,10 methylenetetrahydrofolate reductase C677T homozygous state

Domenico Dell'Edera, Andrea Tinelli, Giusi Natalia Milazzo, Antonio Malvasi, Carone Domenico, Elena Pacella, Compagnoni Pierluigi, Tarantino Giuseppe, Guido Marcello, Lomurno Francesco, Annunziata Anna Epifania
Pages: 609-612
Published online on: 28 June 2013

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Article

Correlation between interleukin‑23 receptor gene polymorphisms and risk of hepatitis B virus infection in patients

Qiliu Peng, Yanping Qin, Zhiping Chen, Yan Deng, Juanjuan Xu, Shan Li, Xue Qin
Pages: 613-620
Published online on: 26 June 2013

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Article

Lefty A protein inhibits TGF-β1-mediated apoptosis in human renal tubular epithelial cells

Ren-Ping Zheng, Tao Bai, Xiao-Guang Zhou, Chang-Gen Xu, Wei Wang, Ming-Wei Xu, Jie Zhang
Pages: 621-625
Published online on: 26 June 2013

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Article

MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944

Deyao Wu, Ping Huang, Linmao Wang, Yunfeng Zhou, Huixing Pan, Ping Qu
Pages: 626-630
Published online on: 31 May 2013

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Article

Selection of anti-cancer-associated gene single-chain variable fragments derived from gastric cancer patients using ribosome display

Lin Xin, Jiaqing Cao, Chuan Liu, Fei Zeng, Hua Cheng, Xiaoyun Hu, Peiqian Zhu, Jianghua Shao
Pages: 631-637
Published online on: 31 May 2013

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Article

Differential effects of paclitaxel and docetaxel on gap junctions affects their cytotoxicities in transfected HeLa cells

Nan Tang, Qin Wang, Dengpan Wu, Suzhi Zhang, Yuan Zhang, Liang Tao
Pages: 638-644
Published online on: 25 June 2013

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Article

Sphingosine kinase‑1 mediates endotoxemia‑induced hyperinflammation in aged animals

Maria Lufrano, Asha Jacob, Mian Zhou, Ping Wang
Pages: 645-649
Published online on: 28 June 2013

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Article

Bacterial artificial chromosomes (BACs)-on-Beads™ as a diagnostic platform for the rapid aneuploidy screening of products of conception

Karen L. Sheath, Lisa Duffy, Philip Asquith, Donald R. Love, Alice M. George
Pages: 650-654
Published online on: 13 June 2013

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Article

Phosphorylation of cMet tyrosine residues in murine ascitic hepatic cancer cell lines with different lymph node metastatic potentials

Ying Li, Xiaohua Huang, Qiaoshu Zhang, Keli Ma
Pages: 655-661
Published online on: 17 June 2013

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Article

Eps8 vaccine exerts prophylactic antitumor effects in a murine model: A novel vaccine for breast carcinoma

Yan-Jie He, Jing Zhou, Tong-Feng Zhao, Liang-Shan Hu, Jing-Ying Gan, Lan Deng, Yuhua Li
Pages: 662-668
Published online on: 10 June 2013

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Article

Immunomodulatory effects of polysaccharopeptide in immunosuppressed mice induced by cyclophosphamide

Rui Huang, Jun Zhang, Yong Liu, Yingying Hao, Chenchen Yang, Kangkang Wu, Shufeng Cao, Chao Wu
Pages: 669-675
Published online on: 25 June 2013

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Article

miR-26a promotes neurite outgrowth by repressing PTEN expression

Baoguo Li, Hanxiao Sun
Pages: 676-680
Published online on: 19 June 2013

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Article

Hemin‑mediated neuroglobin induction exerts neuroprotection following ischemic brain injury through PI3K/Akt signaling

Bei Zhang, Xiuping Ji, Shijun Zhang, Huiyun Ren, Minjuan Wang, Changjiang Guo, Yajun Li
Pages: 681-685
Published online on: 13 June 2013

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Article

Changes in cardiac mitochondrial aldehyde dehydrogenase 2 activity in relation to oxidative stress and inflammatory injury in diabetic rats

Hong-Ju Wang, Pin-Fang Kang, Wen-Juan Wu, Yang Tang, Qiang-Qiang Pan, Hong-Wei Ye, Bi Tang, Zheng-Hong Li, Qin Gao
Pages: 686-690
Published online on: 14 June 2013

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Article

Unphosphorylated heat shock protein 27 suppresses fibroblast growth factor‑2‑stimulated vascular endothelial growth factor release in osteoblasts

Akira Kondo, Haruhiko Tokuda, Rie Matsushima-Nishiwaki, Kenji  Kato, Gen Kuroyanagi, Jun Mizutani, Muneyoshi Fukuoka, Ikuo Wada, Osamu Kozawa, Takanobu Otsuka
Pages: 691-695
Published online on: 19 June 2013

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Article

An improved postconditioning algorithm: Gradually increased reperfusion provides improved cardioprotection in rats

Guoming Zhang, Yuanyuan Sun, Yu Wang, Jing Bai, Tiande Li, Xiaoyan Li, Shaoping Su, Xiuhua Liu
Pages: 696-702
Published online on: 25 June 2013

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Article

Knockdown of FAK inhibits the invasion and metastasis of Tca‑8113 cells in vitro

Wenbo Xiao, Mingxin Jiang, Hongdan Li, Chunshan Li, Rongjian Su, Keqiang Huang
Pages: 703-707
Published online on: 26 June 2013

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Article

1,3‑β‑Glucan affects the balance of Th1/Th2 cytokines by promoting secretion of anti‑inflammatory cytokines in vitro

Ying Chen, Lei Dong, Dong Weng, Fangwei Liu, Laiyu Song, Cuiying Li, Wen Tang, Jie Chen
Pages: 708-712
Published online on: 25 June 2013

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January-2026 Volume 33 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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