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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2013 Volume 8 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Potassium ion channels in retinal ganglion cells (Review)

Yi‑Sheng Zhong, Jing Wang, Wang‑Min Liu, Yi‑Hua Zhu
Pages: 311-319
Published online on: 04 June 2013

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Article Open Access

Ultrasound‑targeted microbubble destruction enhances gene transduction of adeno-associated virus in a less-permissive cell type, NIH/3T3

Lifang Jin, Fan Li, Huiping Wang, Yunhua Li, Fang Wei, Lianfang Du
Pages: 320-326
Published online on: 27 June 2013

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Article

Treadmill exercise ameliorates motor disturbance through inhibition of apoptosis in the cerebellum of valproic acid-induced autistic rat pups

Ji-Eun Kim, Mal-Soon Shin, Tae-Beom Seo, Eun-Sang Ji, Seong-Soo Baek, Sam-Jun Lee, Joon-Ki Park, Chang-Ju Kim
Pages: 327-334
Published online on: 12 June 2013

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Article

Concentration of tissue angiotensin II increases with severity of experimental pancreatitis

Hiroyuki Furukawa, Atsushi Shinmura, Hidehiro Tajima, Tomoya Tsukada, Shin‑Ichi Nakanuma, Koichi Okamoto, Seisho Sakai, Isamu Makino, Keishi Nakamura, Hironori Hayashi, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Tomoharu Miyashita, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tetsuo Ohta, Tomohiko Wakayama, Shoichi Iseki
Pages: 335-338
Published online on: 06 June 2013

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Article

Identification and analysis of microRNAs in the left ventricular myocardium of two-kidney one-clip hypertensive rats

Gang Sun, Hai Hu, Xuyang Tian, Jianwei Yue, Hui Yu, Xiaomin Yang, Zhanli Wang
Pages: 339-344
Published online on: 25 June 2013

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Article

miR-124 inhibits the growth of glioblastoma through the downregulation of SOS1

Zhonghua Lv, Lizhuang Yang
Pages: 345-349
Published online on: 28 June 2013

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Article

cDNA microarray profiling of rat cholangiocarcinoma induced by thioacetamide

Chun‑Nan Yeh, Wen‑Hui Weng, Govinda Lenka, Lee‑Cheng Tsao, Kun‑Chun Chiang, See‑Tong Pang, Tsung‑Wen Chen, Yi‑Yin Jan, Miin‑Fu Chen
Pages: 350-360
Published online on: 10 June 2013

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Article

Cathepsin B inhibition attenuates cardiac dysfunction and remodeling following myocardial infarction by inhibiting the NLRP3 pathway Retraction in /10.3892/mmr.2017.7551

Aiguo Liu, Xuan Gao, Qingbin Zhang, Lianqun Cui
Pages: 361-366
Published online on: 04 June 2013

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Article

Cytotoxic role of advanced glycation end-products in PC12 cells treated with β‑amyloid peptide

Fu‑Ling Yan, Guo‑Ling Han, Guan‑Jin Wu
Pages: 367-372
Published online on: 25 June 2013

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Article

TOFA suppresses ovarian cancer cell growth in vitro and in vivo

Shu Li, Lihua Qiu, Buchu Wu, Haoran Shen, Jing Zhu, Liang Zhou, Liying Gu, Wen Di
Pages: 373-378
Published online on: 31 May 2013

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Article

miR‑203 regulates the proliferation, apoptosis and cell cycle progression of pancreatic cancer cells by targeting Survivin

Dong Xu, Qingguang Wang, Yong An, Lijian Xu
Pages: 379-384
Published online on: 31 May 2013

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Article

Rosuvastatin prevents pressure overload‑induced myocardial hypertrophy via inactivation of the Akt, ERK1/2 and GATA4 signaling pathways in rats

Xue Xu, Lei Zhang, Jiangjiu Liang
Pages: 385-392
Published online on: 25 June 2013

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Article

Swimming exercise alleviates the symptoms of attention-deficit hyperactivity disorder in spontaneous hypertensive rats

Il-Gyu Ko, Sung-Eun Kim, Tae-Woon Kim, Eun-Sang Ji, Mal-Soon Shin, Chang-Ju Kim, Min-Ha Hong, Geon Ho Bahn
Pages: 393-400
Published online on: 19 June 2013

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Article

Time-course analysis of counts and degranulation of mast cells during early intestinal ischemia-reperfusion injury in mice

Mian Ge, Xiaoliang Gan, Dezhao Liu, Wenhua Zhang, Wanling Gao, Pinjie Huang, Ziqing Hei
Pages: 401-406
Published online on: 18 June 2013

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Article

MiRNA-146a regulates the maturation and differentiation of vascular smooth muscle cells by targeting NF-κB expression

Shaohong Dong, Wei Xiong, Jianhui Yuan, Jianghua Li, Jianjun Liu, Xinyun Xu
Pages: 407-412
Published online on: 20 June 2013

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Article

HPV16 infection regulates RASSF1A transcription mediated by p53

Yueshan Lei, Chengjun Hu, Hongxin Xu, Yihao Tian
Pages: 413-418
Published online on: 17 June 2013

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Article

In vitro and in vivo effects of short hairpin RNA targeting integrin-linked kinase in prostate cancer cells

Yeqing Yuan, Yunbei Xiao, Qing Li, Zhenhua Liu, Xiaowei Zhang, Caipeng Qin, Jing Xie, Xiaofeng Wang, Tao Xu
Pages: 419-424
Published online on: 19 June 2013

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Article

Downregulation of T‑cell lymphoma invasion and metastasis‑inducing factor 1 induces cytoskeletal rearrangement and inhibits the invasive capacity of gastric cancer cells

Jin-Ming Zhu, Pei-Wu Yu
Pages: 425-433
Published online on: 07 June 2013

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Article

A new selective vascular endothelial growth factor receptor 2 inhibitor ablates disease in a mouse model of psoriasis

Heng-Xiu Yan, Yong Wang, Xiao-Nong Yang, Li-Xin Fu, Dong-Mei Tang
Pages: 434-438
Published online on: 31 May 2013

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Article

Oxymatrine ameliorates non-alcoholic fatty liver disease in rats through peroxisome proliferator-activated receptor-α activation

Lijuan Shi, Lei Shi, Hefang Zhang, Zhijuan Hu, Chao Wang, Donghui Zhang, Guangyao Song
Pages: 439-445
Published online on: 06 June 2013

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Article

Evaluation of the usefulness of colonoscopy with mucosal biopsies in the follow-up of TNBS-induced colitis in rats

Magdy El-Salhy, Ingvild Haukaas Wendelbo, Doris Gundersen, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 446-450
Published online on: 17 June 2013

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Article

Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease

Magdy El‑Salhy, Ingvild Wendelbo, Doris Gundersen
Pages: 451-455
Published online on: 14 June 2013

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Article

Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma

Junko Hamamoto, Kenzo Soejima, Satoshi Yoda, Katsuhiko Naoki, Sohei Nakayama, Ryosuke Satomi, Hideki Terai, Shinnosuke Ikemura, Takashi Sato, Hiroyuki Yasuda, Yuichiro Hayashi, Michiie Sakamoto, Toru Takebayashi, Tomoko Betsuyaku
Pages: 456-462
Published online on: 11 June 2013

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Article

Expression profiling of lncRNAs in C3H10T1/2 mesenchymal stem cells undergoing early osteoblast differentiation

Changqing Zuo, Zonggui Wang, Hanyun Lu, Zhong Dai, Xinguang Liu, Liao Cui
Pages: 463-467
Published online on: 21 June 2013

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Article

Combination of negative pressure wound therapy with open bone grafting for bone and soft tissue defects

Kai Deng, Ai-Xi Yu, Cheng-Yan Xia, Zong-Huan Li, Wei-Yang Wang
Pages: 468-472
Published online on: 20 June 2013

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Article

Immunocytochemistry of GLUT2, uptake of fluorescent desnitroso-streptozotocin analogs and phosphorylation of D-glucose in INS-1E cells

Myrna Virreira, Iuliana Popescu, Celine Gillet, Ying Zhang, Yevgeniy Leshch, Julian Thimm, Joachim Thiem, Willy J. Malaisse, Abdullah Sener
Pages: 473-479
Published online on: 27 June 2013

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Article

Mechanistic investigation of immunosuppression in patients with condyloma acuminata

Yu-Jie Shi, Jian Yang, Wenlin Yang
Pages: 480-486
Published online on: 06 June 2013

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Article

Mutations in the STAT1‑interacting domain of the hepatitis C virus core protein modulate the response to antiviral therapy

Sadia Anjum, Muhammad Sohail Afzal, Tahir Ahmad, Baber Aslam, Yasir Waheed, Talha Shafi, Ishtiaq Qadri
Pages: 487-492
Published online on: 25 June 2013

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Article

Lentiviral-mediated p38 MAPK RNAi attenuates aldosterone-induced myocyte apoptosis

Yan Zhou, Yuanhong Liang, Jie Wei, Jing Chen, Qizhu Tang
Pages: 493-498
Published online on: 21 June 2013

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Article

Association between coronary artery calcium score and carotid atherosclerotic disease

Qian Zhao, Xinhuai Wu, Jianming Cai, Xihai Zhao, Shaohong Zhao, Li Yang, Zulong Cai
Pages: 499-504
Published online on: 13 June 2013

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Article

Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma

Xiaolong Yang, Ning Huang
Pages: 505-510
Published online on: 31 May 2013

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Article

Recombinant human decorin upregulates p57KIP2 expression in HepG2 hepatoma cell lines

Abdu Selim Hamid, Jinran Li, Yali Wang, Xiaodong Wu, Hassan Abdellah Ahmed Ali, Zhenwu Du, Lihua Bo, Yucheng Zhang, Guizhen Zhang
Pages: 511-516
Published online on: 06 June 2013

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Article

Monoclonal antibody preparation of Golgi phosphoprotein 2 and preliminary application in the early diagnosis of hepatocellular carcinoma

Qiang Ju, Yanjie Zhao, Yanhong Liu, Guohua Zhou, Feng Li, Pingli Xie, Yuehui Li, Guan-Cheng Li
Pages: 517-522
Published online on: 31 May 2013

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Article

MicroRNA‑1 inhibits the proliferation of chinese sika deer‑derived cartilage cells by binding to the 3'-untranslated region of IGF‑1

Wei Hu, Xingyu Meng, Tiancheng Lu, Lei Wu, Ting Li, Mu Li, Yuhua Tian
Pages: 523-528
Published online on: 10 June 2013

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Article

Analysis of a novel protein in human colorectal adenocarcinoma

Kaicheng Wang, Yao Chen
Pages: 529-534
Published online on: 14 June 2013

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Article

Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation

Isoko Kuriyama, Yuki Nakajima, Hiroshi Nishida, Tetsuya Konishi, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina
Pages: 535-542
Published online on: 25 June 2013

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Article

Neuroprotectin D1 attenuates brain damage induced by transient middle cerebral artery occlusion in rats through TRPC6/CREB pathways

Chengye Yao, Jiancheng Zhang, Fang Chen, Yun Lin
Pages: 543-550
Published online on: 25 June 2013

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Article

Arazyme inhibits cytokine expression and upregulates skin barrier protein expression

In Sik Kim, Mi Jin Kim, Dong‑Ha Shin, Kwang‑Hee Son, Ho‑Yong Park, Ji‑Sook Lee
Pages: 551-556
Published online on: 13 June 2013

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Article

The effect of MAPK inhibitors and ROS modulators on cell growth and death of H2O2‑treated HeLa cells

Woo Hyun Park
Pages: 557-564
Published online on: 25 June 2013

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Article

Acid‑induced cell injury and death in lung epithelial cells is associated with the activation of mitogen‑activated protein kinases

Qiuhua Chen, Yingzi Huang, Yi Yang, Haibo Qiu
Pages: 565-570
Published online on: 20 June 2013

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Article

Expansion of decidual CD45RO+ T cells with high expression of CEACAM1 in the early stage of pregnancy

Qi Xie, Qing-Jie Wang, Yun Zhang, Bei-Hua Kong, Bai-Hua Dong, Xun Qu
Pages: 571-578
Published online on: 25 June 2013

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Article

Serum osteopontin concentration is decreased by exercise-induced fat loss but is not correlated with body fat percentage in obese humans

Jeong Soon You, Hye-In Ji, Kyung Ja Chang, Myung Chul Yoo, Hyung-In Yang, In-Kyung Jeong, Kyoung Soo Kim
Pages: 579-584
Published online on: 13 June 2013

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Article

Gastrodin ameliorates Parkinson's disease by downregulating connexin 43

Yu Wang, Zhe Wu, Xu Liu, Qunying Fu
Pages: 585-590
Published online on: 19 June 2013

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Article

Staphylococcal enterotoxin B and α‑toxin induce the apoptosis of ECV304 cells via similar mechanisms

Feng‑Ling Yu, Ting‑Ting Liu, Xiang Zhu, Weng‑Xuan Yang, Tao Zhang, Na Lin, Yong Liu, Cong‑Sen Liu, Jiu Jiang, Jun‑Chang Guan
Pages: 591-596
Published online on: 25 June 2013

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Article

Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cells

Jinfeng Wu, Fuguo Zuo, Juan Du, Pok Fai Wong, Haihong Qin, Jinhua Xu
Pages: 597-602
Published online on: 26 June 2013

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Article

Activation of the p38 MAPK/NF-κB pathway contributes to doxorubicin-induced inflammation and cytotoxicity in H9c2 cardiac cells

Run-Min Guo, Wen-Ming Xu, Jian-Cong Lin, Li-Qiu Mo, Xiao-Xiao Hua, Pei-Xi Chen, Keng Wu, Dong-Dan Zheng, Jian-Qiang Feng
Pages: 603-608
Published online on: 26 June 2013

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Article

Effect of multivitamins on plasma homocysteine in patients with the 5,10 methylenetetrahydrofolate reductase C677T homozygous state

Domenico Dell'Edera, Andrea Tinelli, Giusi Natalia Milazzo, Antonio Malvasi, Carone Domenico, Elena Pacella, Compagnoni Pierluigi, Tarantino Giuseppe, Guido Marcello, Lomurno Francesco, Annunziata Anna Epifania
Pages: 609-612
Published online on: 28 June 2013

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Article

Correlation between interleukin‑23 receptor gene polymorphisms and risk of hepatitis B virus infection in patients

Qiliu Peng, Yanping Qin, Zhiping Chen, Yan Deng, Juanjuan Xu, Shan Li, Xue Qin
Pages: 613-620
Published online on: 26 June 2013

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Article

Lefty A protein inhibits TGF-β1-mediated apoptosis in human renal tubular epithelial cells

Ren-Ping Zheng, Tao Bai, Xiao-Guang Zhou, Chang-Gen Xu, Wei Wang, Ming-Wei Xu, Jie Zhang
Pages: 621-625
Published online on: 26 June 2013

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Article

MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer Retraction in /10.3892/mmr.2023.12944

Deyao Wu, Ping Huang, Linmao Wang, Yunfeng Zhou, Huixing Pan, Ping Qu
Pages: 626-630
Published online on: 31 May 2013

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Article

Selection of anti-cancer-associated gene single-chain variable fragments derived from gastric cancer patients using ribosome display

Lin Xin, Jiaqing Cao, Chuan Liu, Fei Zeng, Hua Cheng, Xiaoyun Hu, Peiqian Zhu, Jianghua Shao
Pages: 631-637
Published online on: 31 May 2013

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Article

Differential effects of paclitaxel and docetaxel on gap junctions affects their cytotoxicities in transfected HeLa cells

Nan Tang, Qin Wang, Dengpan Wu, Suzhi Zhang, Yuan Zhang, Liang Tao
Pages: 638-644
Published online on: 25 June 2013

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Article

Sphingosine kinase‑1 mediates endotoxemia‑induced hyperinflammation in aged animals

Maria Lufrano, Asha Jacob, Mian Zhou, Ping Wang
Pages: 645-649
Published online on: 28 June 2013

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Article

Bacterial artificial chromosomes (BACs)-on-Beads™ as a diagnostic platform for the rapid aneuploidy screening of products of conception

Karen L. Sheath, Lisa Duffy, Philip Asquith, Donald R. Love, Alice M. George
Pages: 650-654
Published online on: 13 June 2013

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Article

Phosphorylation of cMet tyrosine residues in murine ascitic hepatic cancer cell lines with different lymph node metastatic potentials

Ying Li, Xiaohua Huang, Qiaoshu Zhang, Keli Ma
Pages: 655-661
Published online on: 17 June 2013

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Article

Eps8 vaccine exerts prophylactic antitumor effects in a murine model: A novel vaccine for breast carcinoma

Yan-Jie He, Jing Zhou, Tong-Feng Zhao, Liang-Shan Hu, Jing-Ying Gan, Lan Deng, Yuhua Li
Pages: 662-668
Published online on: 10 June 2013

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Article

Immunomodulatory effects of polysaccharopeptide in immunosuppressed mice induced by cyclophosphamide

Rui Huang, Jun Zhang, Yong Liu, Yingying Hao, Chenchen Yang, Kangkang Wu, Shufeng Cao, Chao Wu
Pages: 669-675
Published online on: 25 June 2013

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Article

miR-26a promotes neurite outgrowth by repressing PTEN expression

Baoguo Li, Hanxiao Sun
Pages: 676-680
Published online on: 19 June 2013

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Article

Hemin‑mediated neuroglobin induction exerts neuroprotection following ischemic brain injury through PI3K/Akt signaling

Bei Zhang, Xiuping Ji, Shijun Zhang, Huiyun Ren, Minjuan Wang, Changjiang Guo, Yajun Li
Pages: 681-685
Published online on: 13 June 2013

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Article

Changes in cardiac mitochondrial aldehyde dehydrogenase 2 activity in relation to oxidative stress and inflammatory injury in diabetic rats

Hong-Ju Wang, Pin-Fang Kang, Wen-Juan Wu, Yang Tang, Qiang-Qiang Pan, Hong-Wei Ye, Bi Tang, Zheng-Hong Li, Qin Gao
Pages: 686-690
Published online on: 14 June 2013

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Article

Unphosphorylated heat shock protein 27 suppresses fibroblast growth factor‑2‑stimulated vascular endothelial growth factor release in osteoblasts

Akira Kondo, Haruhiko Tokuda, Rie Matsushima-Nishiwaki, Kenji  Kato, Gen Kuroyanagi, Jun Mizutani, Muneyoshi Fukuoka, Ikuo Wada, Osamu Kozawa, Takanobu Otsuka
Pages: 691-695
Published online on: 19 June 2013

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Article

An improved postconditioning algorithm: Gradually increased reperfusion provides improved cardioprotection in rats

Guoming Zhang, Yuanyuan Sun, Yu Wang, Jing Bai, Tiande Li, Xiaoyan Li, Shaoping Su, Xiuhua Liu
Pages: 696-702
Published online on: 25 June 2013

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Article

Knockdown of FAK inhibits the invasion and metastasis of Tca‑8113 cells in vitro

Wenbo Xiao, Mingxin Jiang, Hongdan Li, Chunshan Li, Rongjian Su, Keqiang Huang
Pages: 703-707
Published online on: 26 June 2013

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Article

1,3‑β‑Glucan affects the balance of Th1/Th2 cytokines by promoting secretion of anti‑inflammatory cytokines in vitro

Ying Chen, Lei Dong, Dong Weng, Fangwei Liu, Laiyu Song, Cuiying Li, Wen Tang, Jie Chen
Pages: 708-712
Published online on: 25 June 2013

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October-2026 Volume 34 Issue 4

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
Published online on: 03 September 2026

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From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
Published online on: 03 September 2026

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Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
Published online on: 02 September 2026

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Correction Open Access

[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
Published online on: 24 August 2026

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Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
Published online on: 21 August 2026

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Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
Published online on: 20 August 2026

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Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Review Open Access

Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Article Open Access

Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Review

Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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Article Open Access

STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Review Open Access

Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Review Open Access

Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Review Open Access

Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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