|
1
|
Lok AS and McMahon BJ: Chronic Hepatitis
B. Hepatology. 45:507–539. 2007. View Article : Google Scholar
|
|
2
|
Jiang YF, Ma ZH, Zhao PW, Pan Y, Liu YY,
Feng JY and Niu JQ: Effect of thymosin-α(1) on T-helper 1 cell and
T-helper 2 cell cytokine synthesis in patients with hepatitis B
virus e antigen-positive chronic hepatitis B. J Int Med Res.
38:2053–2062. 2010.
|
|
3
|
European association for the study of the
liver. EASL Clinical Practice Guidelines: management of chronic
hepatitis B. J Hepatol. 50:227–242. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Nguyen T, Thompson AJ, Bowden S, et al:
Hepatitis B surface antigen levels during the natural history of
chronic hepatitis B: a perspective on Asia. J Hepatol. 52:508–513.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Wong DK, Huang FY, Lai CL, et al: Occult
hepatitis B infection and HBV replicative activity in patients with
cryptogenic cause of hepatocellular carcinoma. Hepatology.
54:829–836. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lau GK, Liang R, Chiu EK, Lee CK and Lam
SK: Hepatic events after bone marrow transplantation in patients
with hepatitis B infection: a case controlled study. Bone Marrow
Transplant. 19:795–799. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Chaiteerakij R, Komolmit P, Sa-nguanmoo P
and Poovorawan Y: Intrahepatic HBV DNA and covalently closed
circular DNA (cccDNA) levels in patients positive for anti-HBc and
negative for HBsAg. Southeast Asian J Trop Med Public Health.
41:867–875. 2010.PubMed/NCBI
|
|
8
|
Sung JJ, Wong ML, Bowden S, et al:
Intrahepatic hepatitis B virus covalently closed circular DNA can
be a predictor of sustained response to therapy. Gastroenterology.
128:1890–1897. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Bowden S, Jackson K, Littlejohn M and
Locarnini S: Quantification of HBV covalently closed circular DNA
from liver tissue by real-time PCR. Methods Mol Med. 95:41–50.
2004.PubMed/NCBI
|
|
10
|
Weinberger KM, Wiedenmann E, Böhm S and
Jilg W: Sensitive and accurate quantitation of hepatitis B virus
DNA using a kinetic fluorescence detection system (TaqMan PCR). J
Virol Methods. 85:75–82. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ramezani A, Banifazl M, Mamishi S, Sofian
M, Eslamifar A and Aghakhani A: The influence of human leukocyte
antigen and IL-10 gene polymorphisms on hepatitis B virus outcome.
Hepat Mon. 12:320–325. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Chang JJ and Lewin SR: Immunopathogenesis
of hepatitis B virus infection. Immunol Cell Biol. 85:16–23. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Sun C, Fu B, Gao Y, Liao X, Sun R, Tian Z
and Wei H: TGF-β1 down-regulation of NKG2D/DAP10 and 2B4/SAP
expression on human NK cells contributes to HBV persistence. PLoS
Pathog. 8:e10025942012.
|
|
14
|
Chinese Society of Hepatology and Chinese
Society of Infectious Diseases; Chinese Medical Association. The
guideline of prevention and treatment for chronic hepatitis B (2010
version). Zhonghua Gan Zang Bing Za Zhi. 19:13–24. 2011.(In
Chinese).
|
|
15
|
Levrero M, Pollicino T, Petersen J,
Belloni L, Raimondo G and Dandri M: Control of cccDNA function in
hepatitis B virus infection. J Hepatol. 51:581–592. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wang M, Qiu N, Lu S, et al: Serum
hepatitis B surface antigen is correlated with intrahepatic total
HBV DNA and cccDNA in treatment-naïve patients with chronic
hepatitis B but not in patients with HBV related hepatocellular
carcinoma. J Med Virol. 85:219–227. 2013.PubMed/NCBI
|
|
17
|
Manesis EK, Papatheodoridis GV, Tiniakos
DG, et al: Hepatitis B surface antigen: relation to hepatitis B
replication parameters in HBeAg-negative chronic hepatitis B. J
Hepatol. 55:61–68. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Pollicino T, Belloni L, Raffa G, Pediconi
N, Squadrito G, Raimondo G and Levrero M: Hepatitis B virus
replication is regulated by the acetylation status of hepatitis B
virus cccDNA-bound H3 and H4 histones. Gastroenterology.
130:823–837. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Vivekanandan P, Thomas D and Torbenson M:
Methylation regulates hepatitis B viral protein expression. J
Infect Dis. 199:1286–1291. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
20
|
Belloni L, Allweiss L, Guerrieri F, et al:
IFN-α inhibits HBV transcription and replication in cell culture
and in humanized mice by targeting the epigenetic regulation of the
nuclear cccDNA minichromosome. J Clin Invest. 122:529–537.
2012.
|
|
21
|
Volz T, Lutgehetmann M, Wachtler P, et al:
Impaired intrahepatic hepatitis B virus productivity contributes to
low viremia in most HBeAg-negative patients. Gastroenterology.
133:843–852. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Werle-Lapostolle B, Bowden S, Locarnini S,
et al: Persistence of cccDNA during the natural history of chronic
hepatitis B and decline during adefovir dipivoxil therapy.
Gastroenterology. 126:1750–1758. 2004. View Article : Google Scholar
|
|
23
|
Chou YC, Jeng KS, Chen ML, et al:
Evaluation of transcriptional efficiency of hepatitis B virus
covalently closed circular DNA by reverse transcription-PCR
combined with the restriction enzyme digestion method. J Virol.
79:1813–1823. 2005. View Article : Google Scholar
|
|
24
|
Xu WS, Zhao KK, Miao XH, Ni W, Cai X,
Zhang RQ and Wang JX: Effect of oxymatrine on the replication cycle
of hepatitis B virus in vitro. World J Gastroenterol. 16:2028–2037.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Jiang Z, Jhunjhunwala S, Liu J, et al: The
effects of hepatitis B virus integration into the genomes of
hepatocellular carcinoma patients. Genome Res. 22:593–601. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Thompson AJ, Nguyen T, Iser D, et al:
Serum hepatitis B surface antigen and hepatitis B e antigen titers:
disease phase influences correlation with viral load and
intrahepatic hepatitis B virus markers. Hepatology. 51:1933–1944.
2010. View Article : Google Scholar
|
|
27
|
Jaroszewicz J, Calle Serrano B, Wursthorn
K, et al: Hepatitis B surface antigen (HBsAg) levels in the natural
history of hepatitis B virus (HBV)-infection: A European
perspective. J Hepatol. 52:514–522. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Chan HL, Wong VW, Tse AM, et al: Serum
hepatitis B surface antigen quantitation can reflect hepatitis B
virus in the liver and predict treatment response. Clin
Gastroenterol Hepatol. 5:1462–1468. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Takkenberg RB, Zaaijer HL, Menting S, et
al: Detection of hepatitis B virus covalently closed circular DNA
in paraffin-embedded and cryo-preserved liver biopsies of chronic
hepatitis B patients. Eur J Gastroenterol Hepatol. 22:952–960.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zhou T, Guo H, Guo JT, Cuconati A, Mehta A
and Block TM: Hepatitis B virus e antigen production is dependent
upon covalently closed circular (ccc) DNA in HepAD38 cell cultures
and may serve as a cccDNA surrogate in antiviral screening assays.
Antiviral Res. 72:116–124. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Moucari R, Mackiewicz V, Lada O, et al:
Early serum HBsAg drop: a strong predictor of sustained virological
response to pegylated interferon alfa-2a in HBeAg-negative
patients. Hepatology. 49:1151–1157. 2009. View Article : Google Scholar : PubMed/NCBI
|
