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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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2014-April Volume 9 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Cx43 in mesenchymal stem cells promotes angiogenesis of the infarcted heart independent of gap junctions

De‑Guo Wang, Feng‑Xiang Zhang, Ming‑Long Chen, Hong‑Jun Zhu, Bing Yang, Ke‑Jiang Cao
Pages: 1095-1102
Published online on: 28 January 2014

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Article

Infusion of human umbilical cord‑derived mesenchymal stem cells effectively relieves liver cirrhosis in DEN‑induced rats

Jingxin Hong, Huajun Jin, Junling Han, Huanzhang Hu, Jian Liu, Linfang Li, Yao Huang, Dandan Wang, Mengchao Wu, Lugui Qiu, Qijun Qian
Pages: 1103-1111
Published online on: 30 January 2014

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Article

Protective effects of Gingko biloba extract 761 on myocardial infarction via improving the viability of implanted mesenchymal stem cells in the rat heart

Yan‑Li Liu, Yan Zhou, Lin Sun, Jiang-Tao Wen, Shi-Jie Teng, Lin Yang, Dong-Shu Du
Pages: 1112-1120
Published online on: 18 February 2014

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Article

Mitogen-activated protein kinase pathway is pivotal for anoikis resistance in metastatic hepatoma cells

Lili Cao, Zhiyong Zhang, Lihui Han, Juan Du, Xiaohong Liang, Yugang Liu, Wensheng Sun
Pages: 1121-1127
Published online on: 14 February 2014

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Article

Role of the local bone renin‑angiotensin system in steroid‑induced osteonecrosis in rabbits

Yongtao Zhang, Kunzheng Wang, Qichun Song, Ruiyu Liu, Wenchen Ji, Le Ji, Chunsheng Wang
Pages: 1128-1134
Published online on: 21 February 2014

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Article

Predictive value of intrahepatic hepatitis B virus covalently closed circular DNA and total DNA in patients with acute hepatitis B and patients with chronic hepatitis B receiving anti‑viral treatment

Peng Ruan, Boping  Zhou, Xiufang Dai, Zequn Sun, Xiaoyan Guo, Jian Huang, Zuojiong Gong
Pages: 1135-1141
Published online on: 20 February 2014

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Article

Extravasation during bladder cancer metastasis requires cortactin‑mediated invadopodia formation

Noriko Tokui, Mihoko Sutoh Yoneyama, Shingo Hatakeyama, Hayato Yamamoto, Takuya Koie, Hisao Saitoh, Kanemitsu Yamaya, Tomihisa Funyu, Toshiya Nakamura, Chikara Ohyama, Shigeru Tsuboi
Pages: 1142-1146
Published online on: 19 February 2014

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Article

Growth inhibition and induction of apoptosis in SGC‑7901 human gastric cancer cells by evodiamine

Li Yang, Xin Liu, Dan Wu, Man Zhang, Guiping Ran, Ying Bi, Hai Huang
Pages: 1147-1152
Published online on: 28 January 2014

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Article

Notch1 silencing inhibits proliferation and invasion in SGC‑7901 gastric cancer cells

Guangbing Wei, Yuanhong Chang, Jianbao Zheng, Sai He, Nanzheng Chen, Xiaolong Wang, Xuejun Sun
Pages: 1153-1158
Published online on: 28 January 2014

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Article

Wnt3a activates β1‑integrin and regulates migration and adhesion of vascular smooth muscle cells

Xiaolin Wu, Jichun Wang, Hong Jiang, Qi Hu, Jing Chen, Jing Zhang, Rui Zhu, Wenwei Liu, Bin Li
Pages: 1159-1164
Published online on: 07 February 2014

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Article

Changes in the expression of the vitamin D receptor and LVSCC‑A1C in the rat hippocampus submitted to single prolonged stress

Li‑Li Ji, Lei Tong, Jun‑Bo Peng, Xue‑Hua Jin, Dan Wei, Bao‑Ku Xu, Zhen‑Yu Wang
Pages: 1165-1170
Published online on: 07 February 2014

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Article

Fusion protein of tapasin and hepatitis B core antigen 18‑27 enhances T helper cell type 1/2 cytokine ratio and antiviral immunity by inhibiting suppressors of cytokine signaling family members 1/3 in hepatitis B virus transgenic mice

Yuyan Tang, Xiaohua Chen, Yi Zhang, Zhenghao Tang, Meng Zhuo, Dan Li, Peng Wang, Guoqing Zang, Yongsheng Yu
Pages: 1171-1178
Published online on: 12 February 2014

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Article

Prognostic factors for renal allograft survival in patients with immunoglobulin A nephropathy: A case control study

Jun-Qi Guo, Bao-Lin Song, Zhi-Xian Wu, Wei-Zhen Wu, Liu-Tao Luo, Xiao-Wen Chen, Fu-Qiang He, Zhi-Yong Zheng, Shun-Liang Yang, Jian-Ming Tan
Pages: 1179-1184
Published online on: 17 February 2014

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Article

Inhibition of Myo6 gene expression by co‑expression of a mutant of transcription factor POU4F3 (BRN‑3C) in hair cells

Deng‑Bin Ma, Jie Chen, Yang Xia, Guang‑Jie Zhu, Xiao‑Feng Ma, Han Zhou, Ya‑Jun Gu, Chen‑Jie Yu, Min‑Sheng Zhu, Xiao‑Yun Qian, Xia Gao
Pages: 1185-1190
Published online on: 17 February 2014

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Article

Identification of TCIRG1 and CLCN7 gene mutations in a patient with autosomal recessive osteopetrosis

Tingting Yu, Yongguo Yu, Jian Wang, Lei Yin, Yunfang Zhou, Daming Ying, Rongkui Huang, Huijin Chen, Shenmei Wu, Yongnian Shen, Qihua Fu, Fuxiang Chen
Pages: 1191-1196
Published online on: 17 February 2014

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Article

Anti-inflammatory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone via NF-κB inactivation in lipopolysaccharide-stimulated RAW 264.7 macrophage

Min Jeong Kim, Hye Hyeon Lee, Jin Woo Jeong, Min Jeong Seo, Byoung Won Kang, Jeong Uck Park, Kyoung-Sook Kim, Young-Su Cho, Kwon-Il Seo, Gi-Young Kim, Jung-In Kim, Yung Hyun Choi, Yong Kee Jeong
Pages: 1197-1203
Published online on: 28 January 2014

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Article

Naringenin inhibits allergen‑induced airway remodeling in a murine model of asthma

Ying Shi, Yan Tan, Shan Mao, Wei Gu
Pages: 1204-1208
Published online on: 10 February 2014

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Article

BMI‑1 is important in bufalin‑induced apoptosis of K562 cells

Xiaoyun Lian, Hao Wang, Xucang Wei, Yi Wang, Qishan Wang, Liang Guo, Yuan Zhao, Xiequn Chen
Pages: 1209-1217
Published online on: 21 February 2014

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Article

Short‑term calorie restriction activates SIRT1‑4 and ­‑7 in cardiomyocytes in vivo and in vitro

Wei Yu, Hui‑Fen Zhou, Rui‑Bo Lin, Yu‑Cai Fu, Wei Wang
Pages: 1218-1224
Published online on: 11 February 2014

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Article

Progesterone alters Nogo-A, GFAP and GAP-43 expression in a rat model of traumatic brain injury

Feng Liu, Fan Liao, Wei Li, Yongfeng Han, Daguang Liao
Pages: 1225-1231
Published online on: 19 February 2014

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Article

Effect of transforming growth factor-β1 on acute lung injury caused by paraquat

Baotian Kan, Xiangdong Jian, Qian Zhou, Jieru Wang, Guangcai Yu, Jing Sun, Yikai Gao
Pages: 1232-1236
Published online on: 07 February 2014

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Article

Inhibitory effect of Lycium barbarum polysaccharides on cell apoptosis and senescence is potentially mediated by the p53 signaling pathway

Guangqing Xia, Nian Xin, Wei Liu, Huimin Yao, Yi Hou, Jie Qi
Pages: 1237-1241
Published online on: 19 February 2014

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Article

Expression of β‑amyloid precursor protein in refractory epilepsy

Xiutian Sima, Jianguo Xu, Jinmei Li, Weiying Zhong, Chao You
Pages: 1242-1248
Published online on: 21 February 2014

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Article

Comparative effects of chlorhexidine and essential oils containing mouth rinse on stem cells cultured on a titanium surface

Jun-Beom Park, Gil Lee, Byeong Gon Yun, Chang-Hyen Kim, Youngkyung Ko
Pages: 1249-1253
Published online on: 20 February 2014

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Article

Liraglutide alleviates diabetic cardiomyopathy by blocking CHOP‑triggered apoptosis via the inhibition of the IRE-α pathway

Yuqiang Ji, Zhao Zhao, Tianzhi Cai, Pengkang Yang, Manli Cheng
Pages: 1254-1258
Published online on: 17 February 2014

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Article

Effects of 5-azacytidine on RUNX3 gene expression and the biological behavior of esophageal carcinoma cells

Shuai Wang, Hong Liu, Zhou Wang, Hua-Xia Chen
Pages: 1259-1265
Published online on: 11 February 2014

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Article

Sequence comparison and phylogenetic analysis of Hepatitis C virus genotype 3 polymerase

Yasir Waheed, Attya Bhatti, Sadia Anjum, Muhammad Ashraf
Pages: 1266-1270
Published online on: 30 January 2014

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Article

Incidence of bcr‑abl fusion transcripts in healthy individuals

Said I. Ismail, Randa G. Naffa, Al‑Motassem F. Yousef, Majd T. Ghanim
Pages: 1271-1276
Published online on: 13 February 2014

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Article

Moist exposed burn ointment promotes cutaneous excisional wound healing in rats involving VEGF and bFGF

Qian‑Li Tang, Shan‑Shan Han, Jing Feng, Jia‑Qi Di, Wen‑Xi Qin, Jun Fu, Qiu‑Yan Jiang
Pages: 1277-1282
Published online on: 28 January 2014

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Article

A correlation analysis of miRNA‑34a and its predicted target genes in leukemia

Ruihong Tang, Juanjuan Li, Mei Yue, Ziqin Liu, Shunqiao Feng, Suoqin Tang, Tianyou Wang
Pages: 1283-1288
Published online on: 03 February 2014

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Article

FH535 inhibits the proliferation of HepG2 cells via downregulation of the Wnt/β‑catenin signaling pathway

Jing Liu, Guangbing Li, Dejie Liu, Jun Liu
Pages: 1289-1292
Published online on: 30 January 2014

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Article

microRNA‑34a/c function as tumor suppressors in Hep‑2 laryngeal carcinoma cells and may reduce GALNT7 expression

Wei Li, Huiping Ma, Ji Sun
Pages: 1293-1298
Published online on: 30 January 2014

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Article

ABCG2 gene amplification and expression in esophageal cancer cells with acquired adriamycin resistance

Liang Liu, Lian Fu Zuo, Jian Wen Guo
Pages: 1299-1304
Published online on: 13 February 2014

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Article

Genetically modified Schwann cells producing glial cell line-derived neurotrophic factor inhibit neuronal apoptosis in rat spinal cord injury

Guomin Liu, Xukai Wang, Guoxi Shao, Qinyi Liu
Pages: 1305-1312
Published online on: 18 February 2014

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Article

Juglans mandshurica Maxim extracts exhibit antitumor activity on HeLa cells in vitro

Nian Xin, Murtaza Hasan, Wei Li, Yan Li
Pages: 1313-1318
Published online on: 21 February 2014

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Article

Astragalosides attenuate learning and memory impairment in rats following ischemia‑reperfusion injury

Yang‑Yang Wu, Wang‑Yang Wu, Hui‑Ling Gong, Wei‑Zu Li, Yan‑Yan Yin
Pages: 1319-1324
Published online on: 19 February 2014

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Article

Sequence analysis of the drug‑resistant rpoB gene in the Mycobacterium tuberculosis L‑form among patients with pneumoconiosis complicated by tuberculosis

Jun Lu, Shan Jiang, Song Ye, Yun Deng, Shuai Ma, Chao‑Pin Li
Pages: 1325-1330
Published online on: 13 February 2014

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Article

Functions and mechanisms of intermittent negative pressure for osteogenesis in human bone marrow mesenchymal stem cells

Zhi Yang, Jian‑Feng Yao, Peng Xu, Jian‑Bing Zhang, Yu‑Min Zhang, Yang‑Jun Zhu, Si‑Qing Qin, Lin Liu, Hui Liu, Wei‑Kun Hou, Ke Xu
Pages: 1331-1336
Published online on: 19 February 2014

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Article

Pharmacological evaluation for anticancer and immune activities of a novel polysaccharide isolated from Boletus speciosus Frost

Yiling Hou, Xiang Ding, Wanru Hou, Bo Song, Ting Wang, Fang Wang, Jian Li, Yichun Zeng, Jie Zhong, Ting Xu, Hongqing Zhu
Pages: 1337-1344
Published online on: 20 February 2014

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Article

Epirubicin directly promotes hepatitis B virus (HBV) replication in stable HBV-expressing cell lines: A novel mechanism of HBV reactivation following anticancer chemotherapy

Lei Xu, Zeng Tu, Ge Xu, Yuwei Wang, WanLong Pan, XingXing  Zhan, Qiang Luo, Yuan Huang, Juan Chen, AiLong Huang
Pages: 1345-1350
Published online on: 20 February 2014

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Article

HPV16E7 silencing enhances susceptibility of CaSki cells to natural killer cells

Huimin Guo, Ruili Hu, Xinlei Guan, Fang Guo, Shuzhen Zhao, Xueying Zhang
Pages: 1351-1354
Published online on: 20 February 2014

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Article

Von Hippel-Lindau gene expression in human endometrium during menstrual cycle

Yan-Yan Lu, Wei-Jie Zhu, Bao-Guo Xie
Pages: 1355-1358
Published online on: 18 February 2014

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Article

Morphological study of the TK cholangiocarcinoma cell line with three-dimensional cell culture

Kohei Akiyoshi, Minori Kamada, Nobutake Akiyama, Masafumi Suzuki, Michiko Watanabe, Kouki Fujioka, Keiichi Ikeda, Shuichi Mizuno, Yoshinobu Manome
Pages: 1359-1364
Published online on: 07 February 2014

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Article

Melittin protein inhibits the proliferation of MG63 cells by activating inositol‑requiring protein‑1α and X‑box binding protein 1‑mediated apoptosis

Qiang Fan, Yuping Hu, Haidong Pang, Jintang Sun, Zhendong Wang, Jianmin Li
Pages: 1365-1370
Published online on: 07 February 2014

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Article

Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways Retraction in /10.3892/mmr.2015.4107

Gongli Yang, Feng Ma, Muxiao Zhong, Lin Fang, Yao Peng, Xiaoming Xin, Jietao Zhong, Wei Zhu, Yali Zhang
Pages: 1371-1375
Published online on: 06 February 2014

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Article

MicroRNA‑122 regulation of the morphology and cytoarchitecture of hepatoma carcinoma cells

Ji‑Chun Jin, Xian Zhang, Xing‑Lin Jin, Chang‑Shi Qian, Hao Jiang, Yang Ruan
Pages: 1376-1380
Published online on: 31 January 2014

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Article

Taraxacum mongolicum extract exhibits a protective effect on hepatocytes and an antiviral effect against hepatitis B virus in animal and human cells

Yuan-Yuan Jia, Rong-Fa Guan, Yi-Hang Wu, Xiao-Ping Yu, Wen-Yan Lin, Yong-Yong Zhang, Tao Liu, Jun Zhao, Shu-Yun Shi, Yu Zhao
Pages: 1381-1387
Published online on: 29 January 2014

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Article

Anti-inflammatory activity of a methanol extract from Ardisia tinctoria on mouse macrophages and paw edema

Hui-Seong Kim, Ji-Won Park, Ok-Kyoung Kwon, Jea-Hong Kim, Sei-Ryang Oh, Hyeong-Kyu Lee, Tran The Bach, Bui Hong Quang, Kyung-Seop Ahn
Pages: 1388-1394
Published online on: 10 February 2014

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Article

Naloxone induces endoplasmic reticulum stress in PC12 cells

Soyoung Seo, Young-Sook Kwon, Kweon Yu, Seung-Whan Kim, O-Yu Kwon, Kyung-Hee Kang, Kisang Kwon
Pages: 1395-1399
Published online on: 07 February 2014

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Article

Plasma levels of soluble Axl correlate with severity of community-acquired pneumonia

Chung-Po Ko, Yung-Luen Yu, Pei-Ching Hsiao, Shun-Fa Yang, Chao-Bin Yeh
Pages: 1400-1404
Published online on: 06 February 2014

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Article

Type II cGMP-dependent protein kinase inhibits ligand‑induced activation of EGFR in gastric cancer cells

Lu Jiang, Yongchang Chen, Yueying Li, Ting Lan, Min Wu, Ying Wang, Hai Qian
Pages: 1405-1409
Published online on: 10 February 2014

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Article

Toll‑like receptor 2 promotes bacterial clearance during the initial stage of pulmonary infection with Acinetobacter baumannii

Chang‑Hwan Kim, Dong‑Jae Kim, Sang‑Jin Lee, Yu‑Jin Jeong, Min‑Jung Kang, Jun‑Young Lee, Jin‑A Choi, Sun‑Jung Kwon, Jae‑Hak Park, Jong‑Hwan Park
Pages: 1410-1414
Published online on: 19 February 2014

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Article

Hexane extracts of Polygonum multiflorum improve tissue and functional outcome following focal cerebral ischemia in mice

Soo Vin Lee, Kyung Ha Choi, Young Whan Choi, Jin Woo Hong, Jin Ung Baek, Byung Tae Choi, Hwa Kyoung Shin
Pages: 1415-1421
Published online on: 11 February 2014

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Article

Effect of angiotensin I-converting enzyme and α-actinin-3 gene polymorphisms on sport performance

Tuba Gunel, Ece Gumusoglu, Mohammad Kazem Hosseini, Eda Yilmazyildirim, Ismail Dolekcap, Kilic Aydinli
Pages: 1422-1426
Published online on: 20 February 2014

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Article

Effect of superoxide dismutase‑entrapped liposomes and protein transduction domain‑superoxide dismutase on human umbilical vein endothelial cells

Shu Zhang, Yu Cao, Li Xie, Dairong Qiao, Yi Cao
Pages: 1427-1433
Published online on: 19 February 2014

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Article

Ginsenoside Rb1 protects hippocampal neurons from high glucose-induced neurotoxicity by inhibiting GSK3β-mediated CHOP induction

Di Liu, Hong Zhang, Wenjuan Gu, Yuqin Liu, Mengren Zhang
Pages: 1434-1438
Published online on: 17 February 2014

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Article

Extracellular high mobility group box chromosomal protein 1 promotes drug resistance by increasing the expression of P‑glycoprotein expression in gastric adenocarcinoma cells

Yuping Yin, Wei Li, Meizhou Deng, Peng Zhang, Qian Shen, Guobing Wang, Kaixiong Tao
Pages: 1439-1443
Published online on: 18 February 2014

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Article

Type II cGMP‑dependent protein kinase inhibits RhoA activation in gastric cancer cells

Ying Wang, Yongchang Chen, Yueying Li, Ting Lan, Hai Qian
Pages: 1444-1452
Published online on: 18 February 2014

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Article

Repression of interferon regulatory factor 3 by the Epstein-Barr virus immediate-early protein Rta is mediated through E2F1 in HeLa cells

Liang-Hua Zhu, Shan Gao, Rui Jin, Li-Li Zhuang, Li Jiang, Ling-Zhi Qiu, Hua-Guo Xu, Guo-Ping Zhou
Pages: 1453-1459
Published online on: 17 February 2014

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Article

Propofol selectively inhibits nuclear factor-κB activity by suppressing p38 mitogen‑activated protein kinase signaling in human EA.hy926 endothelial cells during intermittent hypoxia/reoxygenation

Dongliang Li, Chunling Wang, Ning Li, Li Zhang
Pages: 1460-1466
Published online on: 11 February 2014

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Resveratrol induces apoptosis of bladder cancer cells via miR‑21 regulation of the Akt/Bcl‑2 signaling pathway

Chenxi Zhou, Jun Ding, Yuanwen Wu
Pages: 1467-1473
Published online on: 13 February 2014

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January-2026 Volume 33 Issue 1

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CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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SCImago Journal Rank (SJR): 0.841

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Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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