|
1
|
Dewall J: The ABCs of TBI. Evidence-based
guidelines for adult traumatic brain injury care. JEMS. 35:54–61.
2010.PubMed/NCBI
|
|
2
|
Mustafa AG and Alshboul OA:
Pathophysiology of traumatic brain injury. Neurosciences (Riyadh).
18:222–234. 2013.
|
|
3
|
Stein DM, Lindell A, Murdock KR, et al:
Relationship of serum and cerebrospinal fluid biomarkers with
intracranial hypertension and cerebral hypoperfusion after severe
traumatic brain injury. J Trauma. 70:1096–1103. 2011. View Article : Google Scholar
|
|
4
|
Zhang R, Liu Y, Yan K, et al:
Anti-inflammatory and immunomodulatory mechanisms of mesenchymal
stem cell transplantation in experimental traumatic brain injury. J
Neuroinflammation. 10:1062013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Roberts DJ, Jenne CN, Léger C, et al:
Association between the cerebral inflammatory and matrix
metalloproteinase responses after severe traumatic brain injury in
humans. J Neurotrauma. 30:1727–1736. 2013. View Article : Google Scholar
|
|
6
|
Yang SH, Gangidine M, Pritts TA, Goodman
MD and Lentsch AB: Interleukin 6 mediates neuroinflammation and
motor coordination deficits after mild traumatic brain injury and
brief hypoxia in mice. Shock. 40:471–475. 2013. View Article : Google Scholar
|
|
7
|
Nakamura M, Okada S, Toyama Y and Okano H:
Role of IL-6 in spinal cord injury in a mouse model. Clin Rev
Allergy Immunol. 28:197–204. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hildebrand F, Pape HC and Krettek C: The
importance of cytokines in the posttraumatic inflammatory reaction.
Unfallchirurg. 108:793–794. 796–803. 2005.(In German).
|
|
9
|
Poulsen CB, Penkowa M, Borup R, et al:
Brain response to traumatic brain injury in wild-type and
interleukin-6 knockout mice: a microarray analysis. J Neurochem.
92:417–432. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Van Wagoner NJ and Benveniste EN:
Interleukin-6 expression and regulation in astrocytes. J
Neuroimmunol. 100:124–139. 1999.PubMed/NCBI
|
|
11
|
Campo S, Serlupi-Crescenzi O, Arseni B, et
al: Comparative activity of Sant7 and anti-IL-6, IL-6R monoclonal
antibodies in a murine model of B-cell lymphoma. Cytokine.
31:368–374. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Srirangan S and Choy EH: The role of
interleukin 6 in the pathophysiology of rheumatoid arthritis. Ther
Adv Musculoskelet Dis. 2:247–256. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Tuschl T, Zamore PD, Lehmann R, et al:
Targeted mRNA degradation by double-stranded RNA in vitro. Genes
Dev. 13:3191–3197. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Coelho T, Adams D, Silva A, et al: Safety
and efficacy of RNAi therapy for transthyretin amyloidosis. N Engl
J Med. 369:819–829. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Brummelkamp TR, Bernards R and Agami R: A
system for stable expression of short interfering RNAs in mammalian
cells. Science. 296:550–553. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Feeney DM, Boyeson MG, Linn RT, Murray HM
and Dail WG: Responses to cortical injury: I. Methodology and local
effects of contusions in the rat. Brain Res. 211:67–77. 1981.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Bingham D, John CM, Panter SS and Jarvis
GA: Post-injury treatment with lipopolysaccharide or
lipooligosaccharide protects rat neuronal and glial cell cultures.
Brain Res Bull. 85:403–409. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Spooren A, Kolmus K, Laureys G, et al:
Interleukin-6, a mental cytokine. Brain Res Rev. 67:157–183. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Kotzerke K, Mempel M, Aung T, et al:
Immunostimulatory activity of murine keratinocyte-derived exosomes.
Exp Dermatol. 22:650–655. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ziebell JM and Morganti-Kossmann MC:
Involvement of pro- and anti-inflammatory cytokines and chemokines
in the pathophysiology of traumatic brain injury.
Neurotherapeutics. 7:22–30. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Lu J, Goh SJ, Tng PY, Deng YY, Ling EA and
Moochhala S: Systemic inflammatory response following acute
traumatic brain injury. Front Biosci (Landmark Ed). 14:3795–3813.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Frugier T, Morganti-Kossmann MC, O’Reilly
D and McLean CA: In situ detection of inflammatory mediators in
post mortem human brain tissue after traumatic injury. J
Neurotrauma. 27:497–507. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Harhay MO, Tracy RP, Bagiella E, et al:
Relationship of CRP, IL-6, and fibrinogen with right ventricular
structure and function: the MESA-Right Ventricle Study. Int J
Cardiol. 168:3818–3824. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Caselli C, D’Amico A, Caruso R, et al:
Impact of normalization strategy on cardiac expression of
pro-inflammatory cytokines: evaluation of reference genes in
different human myocardial regions after Left Ventricular Assist
Device support. Cytokine. 63:113–122. 2013. View Article : Google Scholar
|
|
25
|
Chiaretti A, Antonelli A, Mastrangelo A,
et al: Interleukin-6 and nerve growth factor upregulation
correlates with improved outcome in children with severe traumatic
brain injury. J Neurotrauma. 25:225–234. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Woodcock T and Morganti-Kossmann MC: The
role of markers of inflammation in traumatic brain injury. Front
Neurol. 4:182013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Papa L, Ramia MM, Kelly JM, Burks SS,
Pawlowicz A and Berger RP: Systematic review of clinical research
on biomarkers for pediatric traumatic brain injury. J Neurotrauma.
30:324–338. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Patterson ZR and Holahan MR: Understanding
the neuroinflammatory response following concussion to develop
treatment strategies. Front Cell Neurosci. 6:582012. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Erta M, Quintana A and Hidalgo J:
Interleukin-6, a major cytokine in the central nervous system. Int
J Biol Sci. 8:1254–1266. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Liu Y, Fuchs J, Li C and Lin J: IL-6, a
risk factor for hepatocellular carcinoma: FLLL32 inhibits
IL-6-induced STAT3 phosphorylation in human hepatocellular cancer
cells. Cell Cycle. 9:3423–3427. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Mukaino M, Nakamura M, Yamada O, et al:
Anti-IL-6-receptor antibody promotes repair of spinal cord injury
by inducing microglia-dominant inflammation. Exp Neurol.
224:403–414. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Yang Z, Feng J, Li Y, Hu M, et al:
Structure-based design and characterization of a Novel IL-6
antagonist peptide. Mol Immunol. 42:1015–1021. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Boos TL, Cheng K, Greiner E, Deschamps JR,
Jacobson AE and Rice KC: Configurational reassignment and improved
preparation of the competitive IL-6 receptor antagonist
20R,21R-epoxyresibufogenin-3-formate. J Nat Prod. 75:661–668. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Purohit A, Singh A, Ghilchik MW,
Serlupi-Crescenzi O and Reed MJ: Inhibition of IL-6+IL-6 soluble
receptor-stimulated aromatase activity by the IL-6 antagonist, Sant
7, in breast tissue-derived fibroblasts. Br J Cancer. 88:630–635.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Ekström M, Halle M, Bjessmo S, et al:
Systemic inflammation activates the nuclear factor-kappaB
regulatory pathway in adipose tissue. Am J Physiol Endocrinol
Metab. 299:E234–E240. 2010.PubMed/NCBI
|
|
36
|
Israelsson C, Wang Y, Kylberg A, Pick CG,
Hoffer BJ and Ebendal T: Closed head injury in a mouse model
results in molecular changes indicating inflammatory responses. J
Neurotrauma. 26:1307–1314. 2009. View Article : Google Scholar : PubMed/NCBI
|
