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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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October 2014 Volume 10 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of ultraviolet B radiation‑induced microRNAs in normal human dermal papilla cells

Hwa Jun Cha, Ok‑Yeon Kim, Gang Tai Lee, Kwang Sik Lee, Jae Ho Lee, In‑Chul Park, Su‑Jae Lee, Yu Ri Kim, Kyu Joong Ahn, In‑Sook An, Sungkwan An, Seunghee Bae
Pages: 1663-1670
Published online on: 24 July 2014

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Article Open Access

Gene expression profiles of patients with cerebral hematoma following spontaneous intracerebral hemorrhage

Tao Yang, Jianwen Gu, Bin Kong, Yongqin Kuang, Lin Cheng, Jingmin Cheng, Xun Xia, Yuan Ma, Junhai Zhang
Pages: 1671-1678
Published online on: 25 July 2014

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Article

Intermittent cold stress enhances features of atherosclerotic plaque instability in apolipoprotein E‑deficient mice

Xi Zheng, Qiang Wang, Yan Zhang, Dachun Yang, De Li, Bing  Tang, Xiuchuan Li, Yongjian Yang, Shuangtao Ma
Pages: 1679-1684
Published online on: 07 August 2014

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Article Open Access

siRNA‑induced ABCE1 silencing inhibits proliferation and invasion of breast cancer cells

Bo Huang, Hongli Zhou, Xianping Lang, Zhiliang Liu
Pages: 1685-1690
Published online on: 28 July 2014

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Article Open Access

Homology modeling and molecular docking of human pituitary adenylate cyclase‑activating polypeptide I receptor

Lusheng Wu, Wenhua Guang, Xiaojia Chen, An Hong
Pages: 1691-1696
Published online on: 24 July 2014

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Article Open Access

Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G1/S‑phase cell cycle arrest and apoptosis through caspase/cyclin‑CDK pathways

Bin Liu, Zhongyou Zhou, Wei Zhou, Jie Liu, Qingyu Zhang, Juan  Xia, Juntao Liu, Nianping Chen, Mingyi Li, Runzhi Zhu
Pages: 1697-1702
Published online on: 21 July 2014

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Article Open Access

Transcriptome analysis reveals the effect of oral contraceptive use on cervical cancer

Tian Gao, Jianjun Wang, Min Yang, Huaifang Li
Pages: 1703-1708
Published online on: 08 August 2014

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Article Open Access

Alterations of cell cycle control proteins SHP‑1/2, p16, CDK4 and cyclin D1 in radioresistant nasopharyngeal carcinoma cells

Gang Peng, Ru‑Bo Cao, Yue‑Hua Li, Zhen‑Wei Zou, Jing Huang, Qian Ding
Pages: 1709-1716
Published online on: 07 August 2014

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Article Open Access

A novel anti‑cancer effect of resveratrol: reversal of epithelial‑mesenchymal transition in prostate cancer cells

Jianping Li, Tie Chong, Ziming Wang, Haiwen Chen, Hecheng  Li, Jun Cao, Peng Zhang, Hongliang Li
Pages: 1717-1724
Published online on: 23 July 2014

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Article Open Access

Rat hepatic stellate cells alter the gene expression profile and promote the growth, migration and invasion of hepatocellular carcinoma cells

Zhi-Ming Wang, Le-Yuan Zhou, Bin-Bin Liu, Qin-An Jia, Yin-Ying Dong, Yun-Hong Xia, Sheng-Long Ye
Pages: 1725-1733
Published online on: 31 July 2014

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Article Open Access

Berberine induces apoptosis and DNA damage in MG‑63 human osteosarcoma cells

Yu Zhu, Nan Ma, Hui‑Xiang Li, Lin Tian, Yu‑Feng Ba, Bin Hao
Pages: 1734-1738
Published online on: 21 July 2014

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Article Open Access

Combined effect of nerve growth factor and brain‑derived neurotrophic factor on neuronal differentiation of neural stem cells and the potential molecular mechanisms

Feifei Liu, Aiguo Xuan, Yan Chen, Jundu Zhang, Liping Xu, Qijiang Yan, Dahong Long
Pages: 1739-1745
Published online on: 18 July 2014

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Article Open Access

Differentially expressed genes and interacting pathways in bladder cancer revealed by bioinformatic analysis

Yinzhou Shen, Xuelei Wang, Yongchao Jin, Jiasun Lu, Guangming Qiu, Xiaofei Wen
Pages: 1746-1752
Published online on: 18 July 2014

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Article Open Access

Chromogranin A cells in the stomachs of patients with sporadic irritable bowel syndrome

Magdy El-Salhy, Odd Helge Gilja, Trygve Hausken
Pages: 1753-1757
Published online on: 08 August 2014

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Article

Protective effects and mechanisms of total alkaloids of Rubus alceaefolius Poir on non‑alcoholic fatty liver disease in rats

Haiyin Zheng, Jinyan Zhao, Yuqing Zheng, Juan Wu, Yan Liu, Jun Peng, Zhenfeng Hong
Pages: 1758-1764
Published online on: 21 July 2014

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Article Open Access

Effects of high mobility group protein box 1 and toll like receptor 4 pathway on warts caused by human papillomavirus

Hui Weng, Hongbo Liu, Yunhua Deng, Yuyan Xie, Guanxin Shen
Pages: 1765-1771
Published online on: 11 August 2014

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Article Open Access

Novel mitochondrial mutations in the ATP6 and ATP8 genes in patients with breast cancer

Ludmiła Grzybowska-Szatkowska, Brygida Ślaska, Jolanta Rzymowska, Anna Brzozowska, Bolesław Floriańczyk
Pages: 1772-1778
Published online on: 08 August 2014

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Article Open Access

Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: Recruiting histone deacetylase and inhibiting activator protein 1 transcription factors

Qingqiang Shi, Jing Li, Ziqiang Feng, Lvcui Zhao, Lian Luo, Zhimei  You, Danyang Li, Jing Xia, Guowei Zuo, Dilong Chen
Pages: 1779-1785
Published online on: 18 July 2014

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Article Open Access

Targeting complement anaphylatoxin C5a receptor in hyperoxic lung injury in mice

Ying Xu, Zhe Tian, Peiyu Xie
Pages: 1786-1792
Published online on: 18 July 2014

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Article Open Access

Rifampicin improves neuronal apoptosis in LPS-stimulated co‑cultured BV2 cells through inhibition of the TLR-4 pathway

Wei Bi, Lihong Zhu, Xiuna Jing, Zhifen Zeng, Yanran Liang, Anding Xu, Jun Liu, Songhua Xiao, Lianhong Yang, Qiaoyun Shi, Li Guo, Enxiang Tao
Pages: 1793-1799
Published online on: 11 August 2014

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Article Open Access

Functional analysis of the mRNA profile of neutrophil gelatinase‑associated lipocalin overexpression in esophageal squamous cell carcinoma using multiple bioinformatic tools

Bing-Li Wu, Chun-Quan Li, Ze-Peng Du, Fei Zhou, Jian-Jun Xie, Lie‑Wei  Luo, Jian-Yi Wu, Pi-Xian Zhang, Li-Yan Xu, En-Min Li
Pages: 1800-1812
Published online on: 07 August 2014

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Article

Mesenchymal stem cells improve intestinal integrity during severe acute pancreatitis

Xiao-Huang Tu, Shao-Xiong Huang, Wen-Sheng Li, Jing-Xiang Song, Xiao-Li Yang
Pages: 1813-1820
Published online on: 05 August 2014

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Article

Inhibitory effects of Rubi Fructus extracts on hepatic steatosis development in high-fat diet-induced obese mice

Mi Kyung Nam, Hye Ran Choi, Jin Sook Cho, Soo Min Cho, Ki Chan Ha, Tae-Hyeon Kim, Hee-Young Ryu, Young-Ik Lee
Pages: 1821-1827
Published online on: 21 July 2014

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Article

Interleukin‑15: A potent adjuvant enhancing the efficacy of an autologous whole‑cell tumor vaccine against Lewis lung carcinoma

Xi Chen, Jie Ni, Hui Meng, Dandan Li, Yuquan Wei, Yan Luo, Yang Wu
Pages: 1828-1834
Published online on: 08 August 2014

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Article

A genetic pedigree analysis to identify gene mutations involved in femoral head necrosis

Lin Wang, Hehai Pan, Zhen‑An Zhu
Pages: 1835-1838
Published online on: 22 July 2014

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Article

A germline mutation in the miR‑125a coding region reduces miR‑125a expression and is associated with human gastric cancer

Hua Shang, Tao Wang, Feng Shang, Kun‑Ming Huang, Yan‑Qing Li
Pages: 1839-1844
Published online on: 04 August 2014

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Article

MacroH2A suppresses the proliferation of the B16 melanoma cell line

Shaorong Lei, Jianhong Long, Jiaguang Li
Pages: 1845-1850
Published online on: 11 August 2014

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Article

Artemisinin prevents electric remodeling following myocardial infarction possibly by upregulating the expression of connexin 43

Yongwei Gu, Gang Wu, Xin Wang, Xi Wang, Yulin Wang, Congxin Huang
Pages: 1851-1856
Published online on: 30 July 2014

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Article

Association between -799C/T single nucleotide polymorphism of the MMP‑8 promoter region and thoracic aortic dissection

Yun Li, Na Li, Wei Ma, Yuanzhu Jiang, Guoyuan Ma, Lin Zhang
Pages: 1857-1862
Published online on: 01 August 2014

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Article

Effect of siRNA‑induced inhibition of IL‑6 expression in rat cerebral gliocytes on cerebral edema following traumatic brain injury

Bin Xu, Dong‑Ming Yu, Fu‑Sheng Liu
Pages: 1863-1868
Published online on: 07 August 2014

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Article

Selenium treatment significantly inhibits tumor necrosis factor‑α‑induced cell death and tau hyperphosphorylation in neuroblastoma cells

Young Ju Lee, Ji Eun Kim, Moon Hwa Kwak, Jun Go, Seung Yun Yang, Hyeog Soong Kwon, Byoung Chul Kim, Joo Man Kim, Dae Youn Hwang
Pages: 1869-1874
Published online on: 04 August 2014

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Article

Oxygen free radicals and mitochondrial signaling in oligospermia and asthenospermia

Wei‑Dong Zhang, Zhan Zhang, Li‑Ting Jia, Lin‑Lin Zhang, Teng Fu, Yu‑Shan Li, Peng Wang, Lin Sun, Ying Shi, Hui‑Zhen Zhang
Pages: 1875-1880
Published online on: 29 July 2014

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Article

Neuronal nitric oxide synthase, as a downstream signaling molecule of c‑jun, regulates the survival of differentiated PC12 cells

Xiao Cheng, Haoxuan Luo, Zijun Hou, Yan Huang, Jingbo Sun, Lihua Zhou
Pages: 1881-1886
Published online on: 23 July 2014

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Article

Detection of the phosphatase activity of carbonic anhydrase III on a nitrocellulose membrane following 2D gel electrophoresis

He Huang, Hui-Min Ren, Xi-Liang Shang, Xue-Yuan Liu
Pages: 1887-1892
Published online on: 04 August 2014

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Article

Expression and significance of Pin1, β‑catenin and cyclin D1 in hepatocellular carcinoma

Ran Ao, Dao‑Rong Zhang, Ya‑Qi Du, Ying Wang
Pages: 1893-1898
Published online on: 06 August 2014

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Article

Odontogenic differentiation of vascular endothelial growth factor‑transfected human dental pulp stem cells in vitro

Wen Zhang, Wei Liu, Junqi Ling, Zhengmei Lin, Yan Gao, Xueli Mao, Yutao Jian
Pages: 1899-1906
Published online on: 11 August 2014

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Article

Hydrogen sulfide reduces regional myocardial ischemia injury through protection of mitochondrial function

Ying‑Hua Xie, Nan Zhang, Lan‑Fang Li, Qin‑Zeng Zhang, Li‑Jun  Xie, Hong Jiang, Li‑Ping Li, Na Hao, Jian‑Xin Zhang
Pages: 1907-1914
Published online on: 17 July 2014

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Article

Formaldehyde induces bone marrow toxicity in mice by inhibiting peroxiredoxin 2 expression

Guangyan Yu, Qiang Chen, Xiaomei Liu, Caixia Guo, Haiying Du, Zhiwei Sun
Pages: 1915-1920
Published online on: 08 August 2014

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Article

Anthocyanins potentiate the activity of trastuzumab in human epidermal growth factor receptor 2‑positive breast cancer cells in vitro and in vivo

Weihua Liu, Jinmei Xu, Yilun Liu, Xiaoping Yu, Xi Tang, Zhi Wang, Xin Li
Pages: 1921-1926
Published online on: 22 July 2014

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Article

Raltitrexed induces mitochondrial‑mediated apoptosis in SGC7901 human gastric cancer cells

Song Xue, Ying‑Xia Chen, Shu‑Kui Qin, Ai‑Zhen Yang, Lin  Wang, Hai‑Jun Xu, Hai‑Yun Geng
Pages: 1927-1934
Published online on: 01 August 2014

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Article

Decreased osteoclastogenesis, osteoblastogenesis and low bone mass in a mouse model of type 2 diabetes

Fei Xu, Yonghui Dong, Xin Huang, Mi Li, Liang Qin, Ye Ren, Fengjing Guo, Anmin Chen, Shilong Huang
Pages: 1935-1941
Published online on: 30 July 2014

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Article

Protective effects of the p38 MAPK inhibitor SB203580 on NMDA‑induced injury in primary cerebral cortical neurons

Xue‑Wen Liu, En‑Fei Ji, Peng He, Rui‑Xian Xing, Bu‑Xian Tian, Xi‑Dong Li
Pages: 1942-1948
Published online on: 21 July 2014

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Article

Ulinastatin protects cardiomyocytes against ischemia‑reperfusion injury by regulating autophagy through mTOR activation

Jian Xiao, Xiaoyan Zhu, Guangyu Ji, Qian Yang, Bo Kang, Jianquan  Zhao, Feng Yao, Lihui Wu, Xin Ni, Zhinong Wang
Pages: 1949-1953
Published online on: 05 August 2014

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Article

Increased Th17 cells and IL‑17 in rats with traumatic optic neuropathy

Huabin Zheng, Zhuhong Zhang, Na Luo, Yuanyuan Liu, Qingzhong Chen, Hua Yan
Pages: 1954-1958
Published online on: 05 August 2014

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Article

Protein phosphatase 4 promotes hepatic lipogenesis through dephosphorylating acetyl‑CoA carboxylase 1 on serine 79

Xiangyu Meng, Meng Li, Jun Guo, Weiqing Tang, Shu  Wang, Yong Man, Xiuqing Huang, Jian Li
Pages: 1959-1963
Published online on: 18 July 2014

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Article

Resveratrol ameliorates low shear stress‑induced oxidative stress by suppressing ERK/eNOS‑Thr495 in endothelial cells

Zhimei Wang, Junxia Zhang, Bing Li, Xiaofei Gao, Yanrong Liu, Wenxing Mao, Shao‑Liang Chen
Pages: 1964-1972
Published online on: 17 July 2014

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Article

Effect of PTEN and KAI1 gene overexpression on the proliferation, metastasis and radiosensitivity of ASPC‑1 pancreatic cancer cells under hypoxic conditions

Hongyu Li, Jianjun Li, Xu Liu, Jiang Chen, Chunyan Wu, Xiaozhong Guo
Pages: 1973-1977
Published online on: 21 July 2014

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Article

Soluble a‑proliferation‑inducing ligand (sAPRIL), a novel serum biomarker predicting the recurrence and metastasis of pancreatic adenocarcinoma after surgery

Lei Han, Wei Zhang, Fulin Song, Yang Guo, Kejian Guo, Wenping Zhou
Pages: 1978-1984
Published online on: 04 August 2014

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Article

Wnt5a is associated with the differentiation of bone marrow mesenchymal stem cells in vascular calcification by connecting with different receptors

Siming Guan, Zhimin Wang, Fang Xin, Huaping Xin
Pages: 1985-1991
Published online on: 05 August 2014

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Article

High glucose induces Rho/ROCK-dependent visfatin and type I procollagen expression in rat primary cardiac fibroblasts

Rong Yang, Liang Chang, Suyun Liu, Xin Jin, Yongjun Li
Pages: 1992-1998
Published online on: 22 July 2014

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Article

Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF‑β signaling pathway

Fenglin Chen, Mingkai Zhuang, Jun Peng, Xiaozhong Wang, Tingxuan Huang, Sanmei Li, Manqiang Lin, Hongming Lin, Yating Xu, Jianying Li, Zhixin Chen, Yuehong Huang
Pages: 1999-2003
Published online on: 05 August 2014

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Article

Differential expression profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases in females with or without pelvic organ prolapse

Xiaohong Wang, Yiqi Li, Jie Chen, Xiaoli Guo, Han Guan, Candong Li
Pages: 2004-2008
Published online on: 08 August 2014

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Article Open Access

Mass spectrometry-based, label-free quantitative proteomics of round spermatids in mice

Hailong Wang, Yan Li, Lijuan Yang, Baofeng Yu, Ping Yan, Min Pang, Xiaobing Li, Hong Yang, Guoping Zheng, Jun Xie, Rui Guo
Pages: 2009-2024
Published online on: 06 August 2014

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Article

Survivin depletion inhibits tumor growth and enhances chemosensitivity in hepatocellular carcinoma

Yvonne Y.Y. Or, Ariel K.M. Chow, Lui Ng, Sheung Tat Fan, Thomas  C.C. Yau, Ronnie T.P. Poon, Roberta W.C. Pang
Pages: 2025-2030
Published online on: 22 July 2014

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Article

Gleditsia sinensis thorn extract inhibits the proliferation and migration of PDGF‑induced vascular smooth muscle cells

Sung‑Soo Park, Wun‑Jae Kim, Sung‑Kwon Moon
Pages: 2031-2038
Published online on: 28 July 2014

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Article

SCN5A mutations and polymorphisms in patients with ventricular fibrillation during acute myocardial infarction

Tim Boehringer, Peter Bugert, Martin Borggrefe, Elif Elmas
Pages: 2039-2044
Published online on: 21 July 2014

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Article

Histone deacetylase 5 promotes the proliferation of glioma cells by upregulation of Notch 1

Quan Liu, Jie‑Min Zheng, Jia‑Kang Chen, Xian‑Lei Yan, Hong‑Mou Chen, Wei‑Xia Nong, He‑Qing Huang
Pages: 2045-2050
Published online on: 18 July 2014

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Article

Protective effect of proanthocyanidins on anoxia-reoxygenation injury of myocardial cells mediated by the PI3K/Akt/GSK-3β pathway and mitochondrial ATP-sensitive potassium channel

Yanyan Hu, Li Li, Wenbin Yin, Lin Shen, Beian You, Haiqing Gao
Pages: 2051-2058
Published online on: 06 August 2014

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Article

Expression of programmed cell death 5 protein inhibits progression of lung carcinoma in vitro and in vivo via the mitochondrial apoptotic pathway

Shining Xu, Gang Sui, Lei Yuan, Zhiqiang Zou
Pages: 2059-2064
Published online on: 05 August 2014

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Article

Effect and mechanism of Src tyrosine kinase inhibitor sunitinib on the drug-resistance reversal of human A549/DDP cisplatin-resistant lung cancer cell line

Ke Zhang, Xian Wang, Hongyan Wang
Pages: 2065-2072
Published online on: 04 August 2014

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Article

High glucose reduces hepatic glycogenesis by suppression of microRNA‑152

Xiaoyun Zhao, Yonggang Lu, Fenghong Wang, Lin Dou, Lilin Wang, Jun Guo, Jian Li
Pages: 2073-2078
Published online on: 28 July 2014

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Article

microRNA response element‑regulated TIKI2 expression suppresses the tumorigencity of malignant gliomas

Chuan‑You Li, Hong‑Yun Zhang, Yi‑Lu Gao
Pages: 2079-2086
Published online on: 22 July 2014

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Article

Suppressed Krüppel‑like factor 17 expression induces tumor proliferation, metastasis and a poor prognosis in papillary thyroid carcinoma

Wen‑Chun Ye, Li Gao, Jing Huang, Xiang‑Ming Fang, Gang Xie
Pages: 2087-2092
Published online on: 29 July 2014

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Celecoxib induces apoptosis via a mitochondria‑dependent pathway in the H22 mouse hepatoma cell line

Dan Shao, Mujie Kan, Ping Qiao, Yue Pan, Zheng Wang, Xuanang Xiao, Jing Li, Li Chen
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Published online on: 07 August 2014

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miR‑210 regulates esophageal cancer cell proliferation by inducing G2/M phase cell cycle arrest through targeting PLK1

Chenglin Li, Xinliang Zhou, Yadi Wang, Shaowu Jing, Congrong Yang, Guogui Sun, Qing Liu, Yunjie Cheng, Lan Wang
Pages: 2099-2104
Published online on: 23 July 2014

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Inhibition of the interleukin‑23/interleukin‑17 pathway by anti‑interleukin‑23p19 monoclonal antibody attenuates 2,4,6‑trinitrobenzene sulfonic acid‑induced Crohn's disease in rats

Jia Yin Yao, Yi Lu, Min Zhi, Chu Jun Li, Pin Jin Hu, Xiang Gao
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Published online on: 28 July 2014

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1α,25-Dihydroxyvitamin D3 enhances γ-glutamyl transpeptidase activity in LLC-PK1 porcine kidney epithelial cells

Ritsu Ito, Hideyuki Ihara, Takahiro Okada, Yoshitaka Ikeda
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Published online on: 31 July 2014

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Administration of a plasmid that expresses SDF-1α affects the oncogenic potential of mouse bcr-abl-transformed cells

Vincent Lucansky, Monika Krmencikova-Fliegl, Libor Stanek, Vladimir Vonka
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Helicobacter pylori promotes VEGF expression via the p38 MAPK‑mediated COX‑2‑PGE2 pathway in MKN45 cells

Ningning Liu, Qiong Wu, Yan Wang, Hua Sui, Xuan Liu, Ning Zhou, Lihong Zhou, Yifei Wang, Naijing Ye, Xiaoling Fu, Nikitin Alexander Yu, Qi Li
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Published online on: 06 August 2014

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In silico prediction of the T‑cell and IgE‑binding epitopes of Per a 6 and Bla g 6 allergens in cockroaches

Hao Chen, Hai‑Wei Yang, Ji‑Fu Wei, Ai‑Lin Tao
Pages: 2130-2136
Published online on: 21 July 2014

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Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia‑inducible factor‑1α and insulin‑like growth factor‑1 mRNA expression

Mingzhong Rui, Zhanping Huang, Ying Liu, Ziyan Wang, Rui Liu, Jinxiang Fu, Haiwen Huang
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Published online on: 22 July 2014

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Dichloroacetate prevents but not reverses the formation of neointimal lesions in a rat model of severe pulmonary arterial hypertension

Bingbing Li, Jie Yan, Yan Shen, Yong Liu, Zhengliang Ma
Pages: 2144-2152
Published online on: 30 July 2014

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Kanglaite stimulates anticancer immune responses and inhibits HepG2 cell transplantation‑induced tumor growth

Xinli Huang, Jianjie Qin, Sen Lu
Pages: 2153-2159
Published online on: 11 August 2014

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MicroRNA-181 inhibits glioma cell proliferation by targeting cyclin B1

Fei Wang, Ji-Yong Sun, You‑Hou Zhu, Ning-Tao Liu, Yi-Fang Wu, Fei Yu
Pages: 2160-2164
Published online on: 28 July 2014

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Involvement of connexin43 in the acute hyperosmotic stimulus‑induced synthesis and release of vasopressin in the supraoptic nucleus of rats

Shan Jiang, Yong‑Qiang Wang, Cheng‑Feng Xu, Ya‑Na Li, Rong Guo, Ling Li
Pages: 2165-2171
Published online on: 21 July 2014

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HSP60 is involved in the neuroprotective effects of naloxone

Wenjing Cheng, Yunhong Li, Xiaolin Hou, Nan Zhang, Jiao  Ma, Feijia Ding, Fan Li, Zhenhua Miao, Yanli Zhang, Qi Qi, Guanghua  Li, Ying Shen, Juan Liu, Weidong Huang, Yin Wang
Pages: 2172-2176
Published online on: 22 July 2014

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CCAAT/enhancer‑binding protein β regulates interleukin‑6‑induced transmembrane and ubiquitin‑like domain containing 1 gene expression in hepatocytes

Menggang Liu, Tao Yuan, Hongming Liu, Ping Chen
Pages: 2177-2183
Published online on: 06 August 2014

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Continuous hypoxia regulates the osteogenic potential of mesenchymal stem cells in a time-dependent manner

Hao Ding, Song Chen, Jun-Hui Yin, Xue-Tao Xie, Zhen‑Hong  Zhu, You-Shui Gao, Chang-Qing Zhang
Pages: 2184-2190
Published online on: 05 August 2014

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Visceral adipose tissue‑derived serine protease inhibitor inhibits interleukin‑1β‑induced catabolic and inflammatory responses in murine chondrocytes

Jia‑Peng Bao, Li‑Feng Jiang, Jing Li, Wei‑Ping Chen, Peng‑Fei Hu, Li‑Dong Wu
Pages: 2191-2197
Published online on: 11 August 2014

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Synergistic effect of celecoxib in tumor necrosis factor‑related apoptosis‑inducing ligand treatment in osteosarcoma cells

Gong Liu, Ming-Yang Yu, Xu Huang, Dong Zhu, Shihuan Cheng, Renshi Ma, Guishan Gu
Pages: 2198-2202
Published online on: 22 July 2014

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Enforced expression of miR‑101 enhances cisplatin sensitivity in human bladder cancer cells by modulating the cyclooxygenase‑2 pathway

Qiang Bu, Yue Fang, Yuan Cao, Qiaoyun Chen, Yangchen Liu
Pages: 2203-2209
Published online on: 06 August 2014

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Microarray analysis of long non-coding RNA expression in human acute rejection biopsy samples following renal transplantation

Wenbiao Chen, Wujian Peng, Jianrong Huang, Xiangqi Yu, Kuibi Tan, Yuyu Chen, Xiaocong Lin, Deheng Chen, Yong Dai
Pages: 2210-2216
Published online on: 24 July 2014

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January-2026 Volume 33 Issue 1

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CiteScore: 8.5

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SCImago Journal Rank (SJR): 0.841

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Article Number: 51
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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
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Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

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Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

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Article Number: 45
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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