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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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October 2014 Volume 10 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of ultraviolet B radiation‑induced microRNAs in normal human dermal papilla cells

Hwa Jun Cha, Ok‑Yeon Kim, Gang Tai Lee, Kwang Sik Lee, Jae Ho Lee, In‑Chul Park, Su‑Jae Lee, Yu Ri Kim, Kyu Joong Ahn, In‑Sook An, Sungkwan An, Seunghee Bae
Pages: 1663-1670
Published online on: 24 July 2014

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Article Open Access

Gene expression profiles of patients with cerebral hematoma following spontaneous intracerebral hemorrhage

Tao Yang, Jianwen Gu, Bin Kong, Yongqin Kuang, Lin Cheng, Jingmin Cheng, Xun Xia, Yuan Ma, Junhai Zhang
Pages: 1671-1678
Published online on: 25 July 2014

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Article

Intermittent cold stress enhances features of atherosclerotic plaque instability in apolipoprotein E‑deficient mice

Xi Zheng, Qiang Wang, Yan Zhang, Dachun Yang, De Li, Bing  Tang, Xiuchuan Li, Yongjian Yang, Shuangtao Ma
Pages: 1679-1684
Published online on: 07 August 2014

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Article Open Access

siRNA‑induced ABCE1 silencing inhibits proliferation and invasion of breast cancer cells

Bo Huang, Hongli Zhou, Xianping Lang, Zhiliang Liu
Pages: 1685-1690
Published online on: 28 July 2014

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Article Open Access

Homology modeling and molecular docking of human pituitary adenylate cyclase‑activating polypeptide I receptor

Lusheng Wu, Wenhua Guang, Xiaojia Chen, An Hong
Pages: 1691-1696
Published online on: 24 July 2014

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Article Open Access

Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G1/S‑phase cell cycle arrest and apoptosis through caspase/cyclin‑CDK pathways

Bin Liu, Zhongyou Zhou, Wei Zhou, Jie Liu, Qingyu Zhang, Juan  Xia, Juntao Liu, Nianping Chen, Mingyi Li, Runzhi Zhu
Pages: 1697-1702
Published online on: 21 July 2014

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Article Open Access

Transcriptome analysis reveals the effect of oral contraceptive use on cervical cancer

Tian Gao, Jianjun Wang, Min Yang, Huaifang Li
Pages: 1703-1708
Published online on: 08 August 2014

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Article Open Access

Alterations of cell cycle control proteins SHP‑1/2, p16, CDK4 and cyclin D1 in radioresistant nasopharyngeal carcinoma cells

Gang Peng, Ru‑Bo Cao, Yue‑Hua Li, Zhen‑Wei Zou, Jing Huang, Qian Ding
Pages: 1709-1716
Published online on: 07 August 2014

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Article Open Access

A novel anti‑cancer effect of resveratrol: reversal of epithelial‑mesenchymal transition in prostate cancer cells

Jianping Li, Tie Chong, Ziming Wang, Haiwen Chen, Hecheng  Li, Jun Cao, Peng Zhang, Hongliang Li
Pages: 1717-1724
Published online on: 23 July 2014

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Article Open Access

Rat hepatic stellate cells alter the gene expression profile and promote the growth, migration and invasion of hepatocellular carcinoma cells

Zhi-Ming Wang, Le-Yuan Zhou, Bin-Bin Liu, Qin-An Jia, Yin-Ying Dong, Yun-Hong Xia, Sheng-Long Ye
Pages: 1725-1733
Published online on: 31 July 2014

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Article Open Access

Berberine induces apoptosis and DNA damage in MG‑63 human osteosarcoma cells

Yu Zhu, Nan Ma, Hui‑Xiang Li, Lin Tian, Yu‑Feng Ba, Bin Hao
Pages: 1734-1738
Published online on: 21 July 2014

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Article Open Access

Combined effect of nerve growth factor and brain‑derived neurotrophic factor on neuronal differentiation of neural stem cells and the potential molecular mechanisms

Feifei Liu, Aiguo Xuan, Yan Chen, Jundu Zhang, Liping Xu, Qijiang Yan, Dahong Long
Pages: 1739-1745
Published online on: 18 July 2014

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Article Open Access

Differentially expressed genes and interacting pathways in bladder cancer revealed by bioinformatic analysis

Yinzhou Shen, Xuelei Wang, Yongchao Jin, Jiasun Lu, Guangming Qiu, Xiaofei Wen
Pages: 1746-1752
Published online on: 18 July 2014

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Article Open Access

Chromogranin A cells in the stomachs of patients with sporadic irritable bowel syndrome

Magdy El-Salhy, Odd Helge Gilja, Trygve Hausken
Pages: 1753-1757
Published online on: 08 August 2014

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Article

Protective effects and mechanisms of total alkaloids of Rubus alceaefolius Poir on non‑alcoholic fatty liver disease in rats

Haiyin Zheng, Jinyan Zhao, Yuqing Zheng, Juan Wu, Yan Liu, Jun Peng, Zhenfeng Hong
Pages: 1758-1764
Published online on: 21 July 2014

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Article Open Access

Effects of high mobility group protein box 1 and toll like receptor 4 pathway on warts caused by human papillomavirus

Hui Weng, Hongbo Liu, Yunhua Deng, Yuyan Xie, Guanxin Shen
Pages: 1765-1771
Published online on: 11 August 2014

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Article Open Access

Novel mitochondrial mutations in the ATP6 and ATP8 genes in patients with breast cancer

Ludmiła Grzybowska-Szatkowska, Brygida Ślaska, Jolanta Rzymowska, Anna Brzozowska, Bolesław Floriańczyk
Pages: 1772-1778
Published online on: 08 August 2014

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Article Open Access

Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: Recruiting histone deacetylase and inhibiting activator protein 1 transcription factors

Qingqiang Shi, Jing Li, Ziqiang Feng, Lvcui Zhao, Lian Luo, Zhimei  You, Danyang Li, Jing Xia, Guowei Zuo, Dilong Chen
Pages: 1779-1785
Published online on: 18 July 2014

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Article Open Access

Targeting complement anaphylatoxin C5a receptor in hyperoxic lung injury in mice

Ying Xu, Zhe Tian, Peiyu Xie
Pages: 1786-1792
Published online on: 18 July 2014

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Article Open Access

Rifampicin improves neuronal apoptosis in LPS-stimulated co‑cultured BV2 cells through inhibition of the TLR-4 pathway

Wei Bi, Lihong Zhu, Xiuna Jing, Zhifen Zeng, Yanran Liang, Anding Xu, Jun Liu, Songhua Xiao, Lianhong Yang, Qiaoyun Shi, Li Guo, Enxiang Tao
Pages: 1793-1799
Published online on: 11 August 2014

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Article Open Access

Functional analysis of the mRNA profile of neutrophil gelatinase‑associated lipocalin overexpression in esophageal squamous cell carcinoma using multiple bioinformatic tools

Bing-Li Wu, Chun-Quan Li, Ze-Peng Du, Fei Zhou, Jian-Jun Xie, Lie‑Wei  Luo, Jian-Yi Wu, Pi-Xian Zhang, Li-Yan Xu, En-Min Li
Pages: 1800-1812
Published online on: 07 August 2014

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Article

Mesenchymal stem cells improve intestinal integrity during severe acute pancreatitis

Xiao-Huang Tu, Shao-Xiong Huang, Wen-Sheng Li, Jing-Xiang Song, Xiao-Li Yang
Pages: 1813-1820
Published online on: 05 August 2014

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Article

Inhibitory effects of Rubi Fructus extracts on hepatic steatosis development in high-fat diet-induced obese mice

Mi Kyung Nam, Hye Ran Choi, Jin Sook Cho, Soo Min Cho, Ki Chan Ha, Tae-Hyeon Kim, Hee-Young Ryu, Young-Ik Lee
Pages: 1821-1827
Published online on: 21 July 2014

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Article

Interleukin‑15: A potent adjuvant enhancing the efficacy of an autologous whole‑cell tumor vaccine against Lewis lung carcinoma

Xi Chen, Jie Ni, Hui Meng, Dandan Li, Yuquan Wei, Yan Luo, Yang Wu
Pages: 1828-1834
Published online on: 08 August 2014

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Article

A genetic pedigree analysis to identify gene mutations involved in femoral head necrosis

Lin Wang, Hehai Pan, Zhen‑An Zhu
Pages: 1835-1838
Published online on: 22 July 2014

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Article

A germline mutation in the miR‑125a coding region reduces miR‑125a expression and is associated with human gastric cancer

Hua Shang, Tao Wang, Feng Shang, Kun‑Ming Huang, Yan‑Qing Li
Pages: 1839-1844
Published online on: 04 August 2014

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Article

MacroH2A suppresses the proliferation of the B16 melanoma cell line

Shaorong Lei, Jianhong Long, Jiaguang Li
Pages: 1845-1850
Published online on: 11 August 2014

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Article

Artemisinin prevents electric remodeling following myocardial infarction possibly by upregulating the expression of connexin 43

Yongwei Gu, Gang Wu, Xin Wang, Xi Wang, Yulin Wang, Congxin Huang
Pages: 1851-1856
Published online on: 30 July 2014

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Article

Association between -799C/T single nucleotide polymorphism of the MMP‑8 promoter region and thoracic aortic dissection

Yun Li, Na Li, Wei Ma, Yuanzhu Jiang, Guoyuan Ma, Lin Zhang
Pages: 1857-1862
Published online on: 01 August 2014

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Article

Effect of siRNA‑induced inhibition of IL‑6 expression in rat cerebral gliocytes on cerebral edema following traumatic brain injury

Bin Xu, Dong‑Ming Yu, Fu‑Sheng Liu
Pages: 1863-1868
Published online on: 07 August 2014

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Article

Selenium treatment significantly inhibits tumor necrosis factor‑α‑induced cell death and tau hyperphosphorylation in neuroblastoma cells

Young Ju Lee, Ji Eun Kim, Moon Hwa Kwak, Jun Go, Seung Yun Yang, Hyeog Soong Kwon, Byoung Chul Kim, Joo Man Kim, Dae Youn Hwang
Pages: 1869-1874
Published online on: 04 August 2014

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Article

Oxygen free radicals and mitochondrial signaling in oligospermia and asthenospermia

Wei‑Dong Zhang, Zhan Zhang, Li‑Ting Jia, Lin‑Lin Zhang, Teng Fu, Yu‑Shan Li, Peng Wang, Lin Sun, Ying Shi, Hui‑Zhen Zhang
Pages: 1875-1880
Published online on: 29 July 2014

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Article

Neuronal nitric oxide synthase, as a downstream signaling molecule of c‑jun, regulates the survival of differentiated PC12 cells

Xiao Cheng, Haoxuan Luo, Zijun Hou, Yan Huang, Jingbo Sun, Lihua Zhou
Pages: 1881-1886
Published online on: 23 July 2014

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Article

Detection of the phosphatase activity of carbonic anhydrase III on a nitrocellulose membrane following 2D gel electrophoresis

He Huang, Hui-Min Ren, Xi-Liang Shang, Xue-Yuan Liu
Pages: 1887-1892
Published online on: 04 August 2014

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Article

Expression and significance of Pin1, β‑catenin and cyclin D1 in hepatocellular carcinoma

Ran Ao, Dao‑Rong Zhang, Ya‑Qi Du, Ying Wang
Pages: 1893-1898
Published online on: 06 August 2014

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Article

Odontogenic differentiation of vascular endothelial growth factor‑transfected human dental pulp stem cells in vitro

Wen Zhang, Wei Liu, Junqi Ling, Zhengmei Lin, Yan Gao, Xueli Mao, Yutao Jian
Pages: 1899-1906
Published online on: 11 August 2014

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Article

Hydrogen sulfide reduces regional myocardial ischemia injury through protection of mitochondrial function

Ying‑Hua Xie, Nan Zhang, Lan‑Fang Li, Qin‑Zeng Zhang, Li‑Jun  Xie, Hong Jiang, Li‑Ping Li, Na Hao, Jian‑Xin Zhang
Pages: 1907-1914
Published online on: 17 July 2014

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Article

Formaldehyde induces bone marrow toxicity in mice by inhibiting peroxiredoxin 2 expression

Guangyan Yu, Qiang Chen, Xiaomei Liu, Caixia Guo, Haiying Du, Zhiwei Sun
Pages: 1915-1920
Published online on: 08 August 2014

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Article

Anthocyanins potentiate the activity of trastuzumab in human epidermal growth factor receptor 2‑positive breast cancer cells in vitro and in vivo

Weihua Liu, Jinmei Xu, Yilun Liu, Xiaoping Yu, Xi Tang, Zhi Wang, Xin Li
Pages: 1921-1926
Published online on: 22 July 2014

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Article

Raltitrexed induces mitochondrial‑mediated apoptosis in SGC7901 human gastric cancer cells

Song Xue, Ying‑Xia Chen, Shu‑Kui Qin, Ai‑Zhen Yang, Lin  Wang, Hai‑Jun Xu, Hai‑Yun Geng
Pages: 1927-1934
Published online on: 01 August 2014

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Article

Decreased osteoclastogenesis, osteoblastogenesis and low bone mass in a mouse model of type 2 diabetes

Fei Xu, Yonghui Dong, Xin Huang, Mi Li, Liang Qin, Ye Ren, Fengjing Guo, Anmin Chen, Shilong Huang
Pages: 1935-1941
Published online on: 30 July 2014

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Article

Protective effects of the p38 MAPK inhibitor SB203580 on NMDA‑induced injury in primary cerebral cortical neurons

Xue‑Wen Liu, En‑Fei Ji, Peng He, Rui‑Xian Xing, Bu‑Xian Tian, Xi‑Dong Li
Pages: 1942-1948
Published online on: 21 July 2014

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Article

Ulinastatin protects cardiomyocytes against ischemia‑reperfusion injury by regulating autophagy through mTOR activation

Jian Xiao, Xiaoyan Zhu, Guangyu Ji, Qian Yang, Bo Kang, Jianquan  Zhao, Feng Yao, Lihui Wu, Xin Ni, Zhinong Wang
Pages: 1949-1953
Published online on: 05 August 2014

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Article

Increased Th17 cells and IL‑17 in rats with traumatic optic neuropathy

Huabin Zheng, Zhuhong Zhang, Na Luo, Yuanyuan Liu, Qingzhong Chen, Hua Yan
Pages: 1954-1958
Published online on: 05 August 2014

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Article

Protein phosphatase 4 promotes hepatic lipogenesis through dephosphorylating acetyl‑CoA carboxylase 1 on serine 79

Xiangyu Meng, Meng Li, Jun Guo, Weiqing Tang, Shu  Wang, Yong Man, Xiuqing Huang, Jian Li
Pages: 1959-1963
Published online on: 18 July 2014

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Article

Resveratrol ameliorates low shear stress‑induced oxidative stress by suppressing ERK/eNOS‑Thr495 in endothelial cells

Zhimei Wang, Junxia Zhang, Bing Li, Xiaofei Gao, Yanrong Liu, Wenxing Mao, Shao‑Liang Chen
Pages: 1964-1972
Published online on: 17 July 2014

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Article

Effect of PTEN and KAI1 gene overexpression on the proliferation, metastasis and radiosensitivity of ASPC‑1 pancreatic cancer cells under hypoxic conditions

Hongyu Li, Jianjun Li, Xu Liu, Jiang Chen, Chunyan Wu, Xiaozhong Guo
Pages: 1973-1977
Published online on: 21 July 2014

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Article

Soluble a‑proliferation‑inducing ligand (sAPRIL), a novel serum biomarker predicting the recurrence and metastasis of pancreatic adenocarcinoma after surgery

Lei Han, Wei Zhang, Fulin Song, Yang Guo, Kejian Guo, Wenping Zhou
Pages: 1978-1984
Published online on: 04 August 2014

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Article

Wnt5a is associated with the differentiation of bone marrow mesenchymal stem cells in vascular calcification by connecting with different receptors

Siming Guan, Zhimin Wang, Fang Xin, Huaping Xin
Pages: 1985-1991
Published online on: 05 August 2014

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Article

High glucose induces Rho/ROCK-dependent visfatin and type I procollagen expression in rat primary cardiac fibroblasts

Rong Yang, Liang Chang, Suyun Liu, Xin Jin, Yongjun Li
Pages: 1992-1998
Published online on: 22 July 2014

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Article

Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF‑β signaling pathway

Fenglin Chen, Mingkai Zhuang, Jun Peng, Xiaozhong Wang, Tingxuan Huang, Sanmei Li, Manqiang Lin, Hongming Lin, Yating Xu, Jianying Li, Zhixin Chen, Yuehong Huang
Pages: 1999-2003
Published online on: 05 August 2014

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Article

Differential expression profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases in females with or without pelvic organ prolapse

Xiaohong Wang, Yiqi Li, Jie Chen, Xiaoli Guo, Han Guan, Candong Li
Pages: 2004-2008
Published online on: 08 August 2014

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Article Open Access

Mass spectrometry-based, label-free quantitative proteomics of round spermatids in mice

Hailong Wang, Yan Li, Lijuan Yang, Baofeng Yu, Ping Yan, Min Pang, Xiaobing Li, Hong Yang, Guoping Zheng, Jun Xie, Rui Guo
Pages: 2009-2024
Published online on: 06 August 2014

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Article

Survivin depletion inhibits tumor growth and enhances chemosensitivity in hepatocellular carcinoma

Yvonne Y.Y. Or, Ariel K.M. Chow, Lui Ng, Sheung Tat Fan, Thomas  C.C. Yau, Ronnie T.P. Poon, Roberta W.C. Pang
Pages: 2025-2030
Published online on: 22 July 2014

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Article

Gleditsia sinensis thorn extract inhibits the proliferation and migration of PDGF‑induced vascular smooth muscle cells

Sung‑Soo Park, Wun‑Jae Kim, Sung‑Kwon Moon
Pages: 2031-2038
Published online on: 28 July 2014

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Article

SCN5A mutations and polymorphisms in patients with ventricular fibrillation during acute myocardial infarction

Tim Boehringer, Peter Bugert, Martin Borggrefe, Elif Elmas
Pages: 2039-2044
Published online on: 21 July 2014

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Article

Histone deacetylase 5 promotes the proliferation of glioma cells by upregulation of Notch 1

Quan Liu, Jie‑Min Zheng, Jia‑Kang Chen, Xian‑Lei Yan, Hong‑Mou Chen, Wei‑Xia Nong, He‑Qing Huang
Pages: 2045-2050
Published online on: 18 July 2014

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Article

Protective effect of proanthocyanidins on anoxia-reoxygenation injury of myocardial cells mediated by the PI3K/Akt/GSK-3β pathway and mitochondrial ATP-sensitive potassium channel

Yanyan Hu, Li Li, Wenbin Yin, Lin Shen, Beian You, Haiqing Gao
Pages: 2051-2058
Published online on: 06 August 2014

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Article

Expression of programmed cell death 5 protein inhibits progression of lung carcinoma in vitro and in vivo via the mitochondrial apoptotic pathway

Shining Xu, Gang Sui, Lei Yuan, Zhiqiang Zou
Pages: 2059-2064
Published online on: 05 August 2014

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Article

Effect and mechanism of Src tyrosine kinase inhibitor sunitinib on the drug-resistance reversal of human A549/DDP cisplatin-resistant lung cancer cell line

Ke Zhang, Xian Wang, Hongyan Wang
Pages: 2065-2072
Published online on: 04 August 2014

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Article

High glucose reduces hepatic glycogenesis by suppression of microRNA‑152

Xiaoyun Zhao, Yonggang Lu, Fenghong Wang, Lin Dou, Lilin Wang, Jun Guo, Jian Li
Pages: 2073-2078
Published online on: 28 July 2014

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Article

microRNA response element‑regulated TIKI2 expression suppresses the tumorigencity of malignant gliomas

Chuan‑You Li, Hong‑Yun Zhang, Yi‑Lu Gao
Pages: 2079-2086
Published online on: 22 July 2014

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Article

Suppressed Krüppel‑like factor 17 expression induces tumor proliferation, metastasis and a poor prognosis in papillary thyroid carcinoma

Wen‑Chun Ye, Li Gao, Jing Huang, Xiang‑Ming Fang, Gang Xie
Pages: 2087-2092
Published online on: 29 July 2014

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Celecoxib induces apoptosis via a mitochondria‑dependent pathway in the H22 mouse hepatoma cell line

Dan Shao, Mujie Kan, Ping Qiao, Yue Pan, Zheng Wang, Xuanang Xiao, Jing Li, Li Chen
Pages: 2093-2098
Published online on: 07 August 2014

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miR‑210 regulates esophageal cancer cell proliferation by inducing G2/M phase cell cycle arrest through targeting PLK1

Chenglin Li, Xinliang Zhou, Yadi Wang, Shaowu Jing, Congrong Yang, Guogui Sun, Qing Liu, Yunjie Cheng, Lan Wang
Pages: 2099-2104
Published online on: 23 July 2014

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Inhibition of the interleukin‑23/interleukin‑17 pathway by anti‑interleukin‑23p19 monoclonal antibody attenuates 2,4,6‑trinitrobenzene sulfonic acid‑induced Crohn's disease in rats

Jia Yin Yao, Yi Lu, Min Zhi, Chu Jun Li, Pin Jin Hu, Xiang Gao
Pages: 2105-2110
Published online on: 28 July 2014

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1α,25-Dihydroxyvitamin D3 enhances γ-glutamyl transpeptidase activity in LLC-PK1 porcine kidney epithelial cells

Ritsu Ito, Hideyuki Ihara, Takahiro Okada, Yoshitaka Ikeda
Pages: 2111-2115
Published online on: 31 July 2014

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Administration of a plasmid that expresses SDF-1α affects the oncogenic potential of mouse bcr-abl-transformed cells

Vincent Lucansky, Monika Krmencikova-Fliegl, Libor Stanek, Vladimir Vonka
Pages: 2116-2122
Published online on: 28 July 2014

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Helicobacter pylori promotes VEGF expression via the p38 MAPK‑mediated COX‑2‑PGE2 pathway in MKN45 cells

Ningning Liu, Qiong Wu, Yan Wang, Hua Sui, Xuan Liu, Ning Zhou, Lihong Zhou, Yifei Wang, Naijing Ye, Xiaoling Fu, Nikitin Alexander Yu, Qi Li
Pages: 2123-2129
Published online on: 06 August 2014

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In silico prediction of the T‑cell and IgE‑binding epitopes of Per a 6 and Bla g 6 allergens in cockroaches

Hao Chen, Hai‑Wei Yang, Ji‑Fu Wei, Ai‑Lin Tao
Pages: 2130-2136
Published online on: 21 July 2014

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Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia‑inducible factor‑1α and insulin‑like growth factor‑1 mRNA expression

Mingzhong Rui, Zhanping Huang, Ying Liu, Ziyan Wang, Rui Liu, Jinxiang Fu, Haiwen Huang
Pages: 2137-2143
Published online on: 22 July 2014

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Dichloroacetate prevents but not reverses the formation of neointimal lesions in a rat model of severe pulmonary arterial hypertension

Bingbing Li, Jie Yan, Yan Shen, Yong Liu, Zhengliang Ma
Pages: 2144-2152
Published online on: 30 July 2014

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Kanglaite stimulates anticancer immune responses and inhibits HepG2 cell transplantation‑induced tumor growth

Xinli Huang, Jianjie Qin, Sen Lu
Pages: 2153-2159
Published online on: 11 August 2014

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MicroRNA-181 inhibits glioma cell proliferation by targeting cyclin B1

Fei Wang, Ji-Yong Sun, You‑Hou Zhu, Ning-Tao Liu, Yi-Fang Wu, Fei Yu
Pages: 2160-2164
Published online on: 28 July 2014

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Involvement of connexin43 in the acute hyperosmotic stimulus‑induced synthesis and release of vasopressin in the supraoptic nucleus of rats

Shan Jiang, Yong‑Qiang Wang, Cheng‑Feng Xu, Ya‑Na Li, Rong Guo, Ling Li
Pages: 2165-2171
Published online on: 21 July 2014

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Article

HSP60 is involved in the neuroprotective effects of naloxone

Wenjing Cheng, Yunhong Li, Xiaolin Hou, Nan Zhang, Jiao  Ma, Feijia Ding, Fan Li, Zhenhua Miao, Yanli Zhang, Qi Qi, Guanghua  Li, Ying Shen, Juan Liu, Weidong Huang, Yin Wang
Pages: 2172-2176
Published online on: 22 July 2014

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CCAAT/enhancer‑binding protein β regulates interleukin‑6‑induced transmembrane and ubiquitin‑like domain containing 1 gene expression in hepatocytes

Menggang Liu, Tao Yuan, Hongming Liu, Ping Chen
Pages: 2177-2183
Published online on: 06 August 2014

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Continuous hypoxia regulates the osteogenic potential of mesenchymal stem cells in a time-dependent manner

Hao Ding, Song Chen, Jun-Hui Yin, Xue-Tao Xie, Zhen‑Hong  Zhu, You-Shui Gao, Chang-Qing Zhang
Pages: 2184-2190
Published online on: 05 August 2014

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Visceral adipose tissue‑derived serine protease inhibitor inhibits interleukin‑1β‑induced catabolic and inflammatory responses in murine chondrocytes

Jia‑Peng Bao, Li‑Feng Jiang, Jing Li, Wei‑Ping Chen, Peng‑Fei Hu, Li‑Dong Wu
Pages: 2191-2197
Published online on: 11 August 2014

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Synergistic effect of celecoxib in tumor necrosis factor‑related apoptosis‑inducing ligand treatment in osteosarcoma cells

Gong Liu, Ming-Yang Yu, Xu Huang, Dong Zhu, Shihuan Cheng, Renshi Ma, Guishan Gu
Pages: 2198-2202
Published online on: 22 July 2014

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Enforced expression of miR‑101 enhances cisplatin sensitivity in human bladder cancer cells by modulating the cyclooxygenase‑2 pathway

Qiang Bu, Yue Fang, Yuan Cao, Qiaoyun Chen, Yangchen Liu
Pages: 2203-2209
Published online on: 06 August 2014

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Microarray analysis of long non-coding RNA expression in human acute rejection biopsy samples following renal transplantation

Wenbiao Chen, Wujian Peng, Jianrong Huang, Xiangqi Yu, Kuibi Tan, Yuyu Chen, Xiaocong Lin, Deheng Chen, Yong Dai
Pages: 2210-2216
Published online on: 24 July 2014

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Journal Cover
June-2026 Volume 33 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Mechanotransducer Piezo1 drives ventilator‑induced lung injury in lung epithelial cells via the calcineurin/NFATc3 pathway

Min Li, Shu-Li Zhang, Feng Yuan, Dan Feng
Article Number: 183
Published online on: 28 April 2026

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Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review)

Jianjun Lu, Jing Zhu, Liqiong Zhang, Xiang Zheng, Shan Yang, Yatong Sang, Mingli Yang, Yu Tang
Article Number: 182
Published online on: 28 April 2026

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Indium (III) chloride inhibits testicular Leydig cell proliferation by disrupting centrosome copy numbers

Chia-Yih Wang, Ping-Jui Su, Kuan-Chih Wang, Ruei-Ci Lin, Min-Yun Ke, Yen-Ni Teng
Article Number: 181
Published online on: 28 April 2026

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Correction Open Access

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Article Number: 180
Published online on: 27 April 2026

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Natural products and neurocognitive disorders: Mechanistic insights and research advances (Review)

Weiqing Li, Wei Wu, Xiaoqing Huang, Yinghai Liu, Gu Gong, Qingqing Huang
Article Number: 179
Published online on: 27 April 2026

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Research progress and future directions in circadian rhythms for uterine‑related diseases (Review)

Tiantian Ma, Junwei Li, Yi Fang, Tiancheng Xu, Qian Li, Liangjun Xia, Youbing Xia
Article Number: 178
Published online on: 27 April 2026

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Therapeutic potential of tertiary lymphoid structures in breast cancer (Review)

Liangxiao Zhu, Meigui Li, Feng Liu, Fenghou Gao
Article Number: 177
Published online on: 24 April 2026

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Retraction Open Access

[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer

Wei Wei, Cun Liu
Article Number: 176
Published online on: 22 April 2026

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Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

Yulin Liu, Xinye Li, Bo Huang, Xudong Lai, Baoqing Ye, Haixiong Miao, Lixian Zhang, Xifeng Xiong
Article Number: 175
Published online on: 22 April 2026

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Urinary 8‑OHdG and MDA as rapid biodosimetry markers in the lethal/sublethal dose range

Satoru Monzen, Kenji Terada, Yusuke Tawata, Takanori Sato, Nozomi Kousaka, Yasushi Mariya
Article Number: 174
Published online on: 22 April 2026

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[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
Published online on: 20 April 2026

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SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

Yanchen Liu, Yi Zhao, Yanting Yao, Dan Liu, Yilei Sun, Weishi Xu, Hongli Yu, Lijun Chi
Article Number: 172
Published online on: 17 April 2026

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RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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