|
1
|
Tissenbaum HA and Guarente L: Increased
dosage of a sir-2 gene extends lifespan in Caenorhabditis
elegans. Nature. 410:227–230. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Viswanathan M and Guarente L: Regulation
of Caenorhabditis elegans lifespan by sir-2.1 transgenes.
Nature. 477:E1–E2. 2011.
|
|
3
|
Donmez G and Guarente L: Aging and
disease: connections to sirtuins. Aging Cell. 9:285–290. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Guarente L: Franklin H. Epstein Lecture:
Sirtuins, aging, and medicine. N Engl J Med. 364:2235–2244. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Imai S, Armstrong CM, Kaeberlein M and
Guarente L: Transcriptional silencing and longevity protein Sir2 is
an NAD-dependent histone deacetylase. Nature. 403:795–800. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Yamamoto H, Schoonjans K and Auwerx J:
Sirtuin functions in health and disease. Mol Endocrinol.
21:1745–1755. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Banks AS, Kon N, Knight C, et al: SirT1
gain of function increases energy efficiency and prevents diabetes
in mice. Cell Metab. 8:333–341. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Bordone L, Cohen D, Robinson A, et al:
SIRT1 transgenic mice show phenotypes resembling calorie
restriction. Aging Cell. 6:759–767. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Herranz D, Muñoz-Martin M, Cañamero M, et
al: Sirt1 improves healthy ageing and protects from metabolic
syndrome-associated cancer. Nat Commun. 1:32010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Cheng HL, Mostoslavsky R, Saito S, et al:
Developmental defects and p53 hyperacetylation in Sir2 homolog
(SIRT1)-deficient mice. Proc Natl Acad Sci USA. 100:10794–10799.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
McBurney MW, Yang X, Jardine K, Bieman M,
Th’ng J and Lemieux M: The absence of SIR2alpha protein has no
effect on global gene silencing in mouse embryonic stem cells. Mol
Cancer Res. 1:402–409. 2003.PubMed/NCBI
|
|
12
|
Takeda T, Hosokawa M, Takeshita S, et al:
A new murine model of accelerated senescence. Mech Ageing Dev.
17:183–194. 1981. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Flood JF and Morley JE: Learning and
memory in the SAMP8 mouse. Neurosci Biobehav Rev. 22:1–20. 1998.
View Article : Google Scholar
|
|
14
|
Campbell KH and O’Hare AM: Kidney disease
in the elderly: update on recent literature. Curr Opin Nephrol
Hypertens. 17:298–303. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
O’Hare AM, Bertenthal D, Covinsky KE, et
al: Mortality risk stratification in chronic kidney disease: one
size for all ages? J Am Soc Nephrol. 17:846–853. 2006.PubMed/NCBI
|
|
16
|
Lim JH, Kim EN, Kim MY, et al:
Age-associated molecular changes in the kidney in aged mice. Oxid
Med Cell Longev. 2012:1713832012.PubMed/NCBI
|
|
17
|
Sasaki T, Maier B, Bartke A and Scrable H:
Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell.
5:413–422. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Mortuza R, Chen S, Feng B, Sen S and
Chakrabarti S: High glucose induced alteration of SIRTs in
endothelial cells causes rapid aging in a p300 and FOXO regulated
pathway. PLoS One. 8:e545142013. View Article : Google Scholar
|
|
19
|
Miyamoto M: Characteristics of age-related
behavioral changes in senescence-accelerated mouse SAMP8 and
SAMP10. Exp Gerontol. 32:139–148. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Powers DC, Morley JE and Flood JF:
Age-related changes in LFA-1 expression, cell adhesion, and
PHA-induced proliferation by lymphocytes from
senescence-accelerated mouse (SAM)-P/8 and SAM-R/1 substrains. Cell
Immunol. 141:444–456. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Morley JE: The SAMP8 mouse: a model of
Alzheimer disease? Biogerontology. 3:57–60. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Morley JE, Armbrecht HJ, Farr SA and Kumar
VB: The senescence accelerated mouse (SAMP8) as a model for
oxidative stress and Alzheimer’s disease. Biochim Biophys Acta.
1822:650–656. 2012.
|
|
23
|
Asher G, Gatfield D, Stratmann M, et al:
SIRT1 regulates circadian clock gene expression through PER2
deacetylation. Cell. 134:317–328. 2008. View Article : Google Scholar
|
|
24
|
Belden WJ and Dunlap JC: SIRT1 is a
circadian deacetylase for core clock components. Cell. 134:212–214.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Salminen A, Kauppinen A, Suuronen T and
Kaarniranta K: SIRT1 longevity factor suppresses NF-kappaB -driven
immune responses: regulation of aging via NF-kappaB acetylation?
Bioessays. 30:939–942. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sequeira J, Boily G, Bazinet S, et al:
sirt1-null mice develop an autoimmune-like condition. Exp Cell Res.
314:3069–3074. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Chong ZZ, Shang YC, Wang S and Maiese K:
SIRT1: new avenues of discovery for disorders of oxidative stress.
Expert Opin Ther Targets. 16:167–178. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Qin W, Yang T, Ho L, et al: Neuronal SIRT1
activation as a novel mechanism underlying the prevention of
Alzheimer disease amyloid neuropathology by calorie restriction. J
Biol Chem. 281:21745–21754. 2006. View Article : Google Scholar
|
|
29
|
Kim D, Nguyen MD, Dobbin MM, et al: SIRT1
deacetylase protects against neurodegeneration in models for
Alzheimer’s disease and amyotrophic lateral sclerosis. EMBO J.
26:3169–3179. 2007.
|
