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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2014 Volume 10 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Hepatocyte growth factor activator inhibitor type‑1 in cancer: Advances and perspectives (Review)

Qiaoli Zheng, Haijian Wu, Jiang Cao, Jingjia Ye
Pages: 2779-2785
Published online on: 13 October 2014

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Article Open Access

Genistein decreases cellular redox potential, partially suppresses cell growth in HL‑60 leukemia cells and sensitizes cells to γ‑radiation‑induced cell death

In Gyu Kim, Jin Sik Kim, Jae Ha Lee, Eun Wie Cho
Pages: 2786-2792
Published online on: 08 October 2014

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Article Open Access

Proteome changes in mesenteric lymph induced by sepsis

Ping Zhang, Yan Li, Lian‑Dong Zhang, Liang‑Hua  Wang, Xi Wang, Chao He, Zhao‑Fen Lin
Pages: 2793-2804
Published online on: 18 September 2014

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Article Open Access

Nicotinic acid modulates intracellular calcium concentration and disassembles the cytoskeleton

Jiejing Li, Yanxi Li, Penghui Zhang, Hua Niu, Yu Shi
Pages: 2805-2810
Published online on: 18 September 2014

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Article

Coxsackievirus B detection in cases of myocarditis, myopericarditis, pericarditis and dilated cardiomyopathy in hospitalized patients

Imed Gaaloul, Samira Riabi, Rafik Harrath, Timothy Hunter, Khaldoun B. Hamda, Assia B. Ghzala, Sally Huber, Mahjoub Aouni
Pages: 2811-2818
Published online on: 18 September 2014

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Article Open Access

Increased production of suilysin contributes to invasive infection of the Streptococcus suis strain 05ZYH33

Zhengxin He, Yaya Pian, Zhiqiang Ren, Lili Bi, Yuan Yuan, Yuling Zheng, Yongqiang Jiang, Fukun Wang
Pages: 2819-2826
Published online on: 22 September 2014

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Article Open Access

Tumor cell lysate induces the immunosuppression and apoptosis of mouse immunocytes

Bohan Dong, Guangli Dai, Lei Xu, Yao Zhang, Liefeng Ling, Lingling Sun, Jun Lv
Pages: 2827-2834
Published online on: 02 October 2014

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Article Open Access

Low-magnitude high-frequency loading, by whole-body vibration, accelerates early implant osseointegration in ovariectomized rats

Yong-Qiang Liang, Meng-Chun Qi, Jiang Xu, Juan Xu, Hua-Wei Liu, Wei Dong, Jin-Yuan Li, Min Hu
Pages: 2835-2842
Published online on: 23 September 2014

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Article Open Access

Short hairpin RNA targeting Notch2 inhibits U87 human glioma cell proliferation by inducing cell cycle arrest and apoptosis in vitro and in vivo

Xuezhen Li, Xin He, Wei Tian, Jianzhen Wang
Pages: 2843-2850
Published online on: 15 October 2014

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Article Open Access

Insights into the paracrine effects of uterine natural killer cells

Xin Gong, Yanxia Liu, Zhenzhen Chen, Cai Xu, Qiudan Lu, Zhe Jin
Pages: 2851-2860
Published online on: 13 October 2014

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Article Open Access

D‑galactose‑induced mitochondrial DNA oxidative damage in the auditory cortex of rats

Zhengde Du, Qiong Yang, Tao Zhou, Lin Liu, Shuo Li, Shixiong Chen, Chunsheng Gao
Pages: 2861-2867
Published online on: 15 October 2014

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Article Open Access

Protein-protein interaction analysis of distinct molecular pathways in two subtypes of colorectal carcinoma

Hanzhang Chen, Yunzhen Fang, Hailong Zhu, Shuai Li, Tao Wang, Pan Gu, Xia Fang, Yunjin Wu, Jun Liang, Yu Zeng, Long Zhang, Weizhe Qiu, Lanjing Zhang, Xianghua Yi
Pages: 2868-2874
Published online on: 22 September 2014

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Article Open Access

Ischemic postconditioning prevents renal ischemia reperfusion injury through the induction of heat shock proteins in rats

Qiongmei Guo, Xuefang Du, Yanli Zhao, Dong Zhang, Lihui Yue, Zhenxian Wang
Pages: 2875-2881
Published online on: 14 October 2014

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Article Open Access

Inducing human parthenogenetic embryonic stem cells into islet‑like clusters

Jin Li, Jingjing He, Ge Lin, Guangxiu Lu
Pages: 2882-2890
Published online on: 22 September 2014

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Article Open Access

Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel‑7402/5‑fluorouracil cells Corrigendum in /10.3892/mmr.2022.12691

Sunbin Ling, Yu Tian, Haiquan Zhang, Kaiqi Jia, Tingting Feng, Deguang Sun, Zhenming Gao, Fei Xu, Zhaoyuan Hou, Yan Li, Liming Wang
Pages: 2891-2897
Published online on: 08 October 2014

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Article Open Access

Effects of gastrokine‑2 expression on gastric cancer cell apoptosis by activation of extrinsic apoptotic pathways

Lin‑Sen Shi, Hao Wang, Feng Wang, Min Feng, Meng Wang, Wen‑Xian Guan
Pages: 2898-2904
Published online on: 30 September 2014

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Article Open Access

Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells

Meng Zhang, Zhi-Gang Bian, Yi Zhang, Jia-He Wang, Liang Kan, Xin Wang, Hui-Yan Niu, Ping He
Pages: 2905-2911
Published online on: 18 September 2014

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Article Open Access

A polymorphism site in the pre‑miR‑34a coding region reduces miR‑34a expression and promotes osteosarcoma cell proliferation and migration

Honglin Lv, Jingfang Pei, Hongtao Liu, Haiyan Wang, Jun Liu
Pages: 2912-2916
Published online on: 18 September 2014

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Article Open Access

Ezetimibe prevents the development of non‑alcoholic fatty liver disease induced by high‑fat diet in C57BL/6J mice

Xiang Wang, Qiaohua Ren, Tao Wu, Yong Guo, Yong Liang, Subo Liu
Pages: 2917-2923
Published online on: 10 October 2014

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Article

Voluntary wheel running ameliorates symptoms of MK-801-induced schizophrenia in mice

Tae-Woon Kim, Hyun-Sik Kang, Joon-Ki Park, Sam-Jun Lee, Sang-Bin Baek, Chang-Ju Kim
Pages: 2924-2930
Published online on: 15 October 2014

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Article

Caffeine enhances micturition through neuronal activation in micturition centers

Young‑Sam Cho, Il‑Gyu Ko, Sung‑Eun Kim, Lakkyong Hwan, Mal‑Soon Shin, Chang‑Ju  Kim, Sang‑Hoon Kim, Jun‑Jang Jin, Jun‑Young Chung, Khae‑Hawn Kim
Pages: 2931-2936
Published online on: 15 October 2014

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Article

Characterization of sphere‑forming cells with stem‑like properties from the gastric cancer cell lines MKN45 and SGC7901

Xuming Wang, Feng Zou, Hao Deng, Zhengqi Fu, Yan Li, Lixia Wu, Zhaoyi Wang, Lijiang Liu
Pages: 2937-2941
Published online on: 26 September 2014

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Article

Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint

Xingxiao Gao, Peng Sun, Mingqi Qiao, Sheng Wei, Ling Xue, Huiyun Zhang
Pages: 2942-2948
Published online on: 26 September 2014

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Article

Analysis of DAZL SNP260 and SNP386 in infertile Chinese males using multi-analyte suspension array

Yijian Zhu, Mingfu Ma, Ling Wan, Danyan Zhang, Letian Zhao, Li Wei, Lianbing Li
Pages: 2949-2954
Published online on: 14 October 2014

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Article

Effects of small interfering RNA interference of connexin 37 on subcutaneous gastric tumours in mice

Yuanming Jing, Suxia Guo, Xiaoping Zhang, Aijing  Sun, Feng Tao, Haixing Ju, Haixin Qian
Pages: 2955-2960
Published online on: 08 October 2014

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Article

N‑acetyl‑L‑cysteine reduces arsenite‑induced cytotoxicity through chelation in U937 monocytes and macrophages

Sidra Ghani, Noureen Khan, Chihaya Koriyama, Suminori Akiba, Megumi Yamamoto
Pages: 2961-2966
Published online on: 08 October 2014

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Article

LY294002 suppresses the malignant phenotype and sensitizes osteosarcoma cells to pirarubicin chemotherapy

Xin Hua Long, Zhen Hao Zhong, Ai Fen Peng, Liang  Bo Zhu, Heng Wang, Guo Mei Zhang, Zhi Li Liu
Pages: 2967-2972
Published online on: 09 October 2014

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Article

Role of ubiquitin-specific peptidase 22 in carcinogenesis of human pharyngeal squamous cell carcinoma

Yunling Dou, Jiaping Lin, Haihua Shu, Nan Jiang
Pages: 2973-2978
Published online on: 22 September 2014

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Article

Erythropoietin promotes retinal angiogenesis in a mouse model

Chen-Ting Wen, Tao He, Yi-Qiao Xing
Pages: 2979-2984
Published online on: 23 September 2014

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Article

Stathmin is key in reversion of doxorubicin resistance by arsenic trioxide in osteosarcoma cells

Tao Feng, Guanglei Qiao, Li Feng, Weixiang Qi, Yujing Huang, Yang Yao, Zan Shen
Pages: 2985-2992
Published online on: 09 October 2014

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Article

Dual matrilineal geographic distribution of Korean type 2 diabetes mellitus-associated -11,377 G adiponectin allele

Jee-Hye Choi, Na Young Min, Sang Kil Park, Lkhagvasuren Gavaachimed, Young  Jong Ko, Sung Hoon Han, Kyung Yong Kim, Kijung Kim, Kwang Ho Lee, Ae Ja Park
Pages: 2993-3002
Published online on: 14 October 2014

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Article

Inhibition of autophagy alleviates the senescent state of rat mesenchymal stem cells during long-term culture

Yong Zheng, Cheng-Jun Hu, Ru-Hong Zhuo, Yue-Shan Lei, Na-Na Han, Liu He
Pages: 3003-3008
Published online on: 10 October 2014

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Article

Crotoxin suppresses the tumorigenic properties and enhances the antitumor activity of Iressa® (gefinitib) in human lung adenocarcinoma SPCA‑1 cells

Junhua Wang, Xiuguang Qin, Zhiqiang Zhang, Meiling Chen, Ying Wang, Baoqin Gao
Pages: 3009-3014
Published online on: 09 October 2014

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Article

Effect of triptolide on the regulation of ATP‑binding cassette transporter A1 expression in lipopolysaccharide‑induced acute lung injury of rats

Jun Chen, Jianlin Gao, Jianping Yang, Yukun Zhang, Lina Wang
Pages: 3015-3020
Published online on: 14 October 2014

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Article

Effects of calcium signaling on coagulation factor VIIa-induced proliferation and migration of the SW620 colon cancer cell line

Ying Wu, Jing Wang, Hong Zhou, Xiaoyan Yu, Lichao Hu, Fanlu Meng, Shuanghong Jiang
Pages: 3021-3026
Published online on: 15 October 2014

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Article

Enhancement of the effects of gemcitabine against pancreatic cancer by oridonin via the mitochondrial caspase-dependent signaling pathway

Dian-Lei Liu, He-Qi Bu, Hai-Min Jin, Jin-Feng Zhao, Ye Li, Hai Huang
Pages: 3027-3034
Published online on: 19 September 2014

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Article

Inhibitory activity of Socheongryong‑tang and its constituent components against the production of RANTES, eotaxin, eotaxin‑3 and MMP‑9 from BEAS‑2B cells

Jung-Hoon Kim, Woo‑Young Jeon, Mee‑Young Lee, Chang‑Seob  Seo, Hye‑Sun Lim, Hyeun‑Kyoo Shin
Pages: 3035-3046
Published online on: 14 October 2014

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Article

Protective effect of polydatin on learning and memory impairments in neonatal rats with hypoxic‑ischemic brain injury by up‑regulating brain‑derived neurotrophic factor

Jin Sun, Yunxia Qu, Huiming He, Xiaolei Fan, Yuanhua Qin, Weifeng Mao, Lixin Xu
Pages: 3047-3051
Published online on: 18 September 2014

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Article

Dual specificity phosphatase 6 suppresses the growth and metastasis of prostate cancer cells

Xiaolei Zhai, Qianhe Han, Zhongjie Shan, Xiaowei Qu, Liang Guo, Yudong Zhou
Pages: 3052-3058
Published online on: 18 September 2014

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Article

Expression of the Annexin A1 gene is associated with suppression of growth, invasion and metastasis of nasopharyngeal carcinoma

Aifeng Liu, Weiguo Huang, Guqing Zeng, Xiaohua Ma, Xiao Zhou, Yafei Wang, Chenjie Ouyang, Ailan Cheng
Pages: 3059-3067
Published online on: 15 October 2014

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Article

Adipose-derived stem cells promote human dermal fibroblast function and increase senescence-associated β‑galactosidase mRNA expression through paracrine effects

Xiao Shen, Yunpeng Du, Weimin Shen, Bin Xue, Yu Zhao
Pages: 3068-3072
Published online on: 13 October 2014

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Article

MicroRNA-214 regulates osteosarcoma survival and growth by directly targeting phosphatase and tensin homolog

Xuming Wang, Jiabing Sun, Chunjiang Fu, Dewei Wang, Zhenggang Bi
Pages: 3073-3079
Published online on: 09 October 2014

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Article

Upregulated microRNA-199a-5p inhibits nuclear receptor corepressor 1 translation in mice with non‑alcoholic steatohepatitis

Binggui Zhang, Rongqi Wang, Jinghua Du, Jingya Niu, Rui Zhang, Shunjiang Xu, Xuemin Niu, Qingfu Zhang, Yuemin Nan
Pages: 3080-3086
Published online on: 23 September 2014

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Article

Screening candidate genes associated with bladder cancer using DNA microarray

Axiang Xu, Chunyang Wang, Shengkun Sun
Pages: 3087-3091
Published online on: 15 October 2014

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Article

Effects and mechanism of downregulation of COX‑2 expression by RNA interference on proliferation and apoptosis of human breast cancer MCF‑7 cells

Hui Han, Sheng Yang, Shun‑Guo Lin, Chun‑Sen Xu, Zhong‑Hua Han
Pages: 3092-3098
Published online on: 15 October 2014

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Article

Upregulation of forkhead box O3 transcription is involved in C2-ceramide induced apoptosis and autophagy in ovarian cancer cells in vitro

Zhishan Jin, Lang Zheng, Xiaoyan Xin, Yuanyue Li, Teng Hua, Tingting Wu, Hongbo Wang
Pages: 3099-3105
Published online on: 15 October 2014

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Article

Serum amyloid A promotes osteosarcoma invasion via upregulating αvβ3 integrin

Peng Ren, Deshun Sun, Dajiang Xin, Wanli Ma, Peng Chen, Hongwei Gao, Shouqiang Zhang, Mingzhi Gong
Pages: 3106-3112
Published online on: 14 October 2014

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Article

Modulation of hepatitis B surface antigen secretion by annexin II expressed in hepatitis B virus‑producing hepatoma cells

Yaming Liu, Pujun Gao
Pages: 3113-3117
Published online on: 30 September 2014

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Article

Preliminary screening of differentially expressed circulating microRNAs in patients with steroid‑induced osteonecrosis of the femoral head

Xingshan Wang, Wenwei Qian, Zhihong Wu, Yanyan Bian, Xisheng Weng
Pages: 3118-3124
Published online on: 15 October 2014

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Article

Inhibition of hepatocellular carcinoma by fulvestrant involves the estrogen receptor α and Wnt pathways in vitro and in patients

Cong-Jun Wang, De-Kai Guo, Tian-Geng You, Dong-Wei Shen, Chao  Wang, Lin Tang, Jian Wang, Rong-Hua Xu, Hui Zhang
Pages: 3125-3131
Published online on: 23 September 2014

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Article

Berberine sensitizes rapamycin‑mediated human hepatoma cell death in vitro

Na Guo, Aili Yan, Xingchun Gao, Yanke Chen, Xinying  He, Zhifang Hu, Man Mi, Xu Tang, Xingchun Gou
Pages: 3132-3138
Published online on: 08 October 2014

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Article

Function of Hsf1 in SV40 T‑antigen‑transformed HEK293T cells

Qiying Jiang, Zhi Zhang, Yanzhong Hu, Yuanfang Ma
Pages: 3139-3144
Published online on: 09 October 2014

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Article

14-3-3ε functions as an oncogene in SGC7901 gastric cancer cells through involvement of cyclin E and p27kip1

Xiaoxiang Gong, Lu Yan, Huan Gu, Yibing Mu, Gele Tong, Guiying Zhang
Pages: 3145-3150
Published online on: 02 October 2014

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Article

Polymorphism of the SRD5A2 gene and the risk of prostate cancer

Róbert Dušenka, Roman Tomaškin, Ján Kliment, Dušan Dobrota, Svetlana Dušenková, Marta Vilčková, Monika Kmeť'ová Sivoňová
Pages: 3151-3156
Published online on: 10 October 2014

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Article

Protective effect of Urtica dioica methanol extract against experimentally induced urinary calculi in rats

Haiying Zhang, Ning Li, Kun Li, Peng Li
Pages: 3157-3162
Published online on: 08 October 2014

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Article

Investigation of MEK activity in COS7 cells entering mitosis

Huaiping Shi, Tianying Zhang, Yongqing Yi, Jun Luo
Pages: 3163-3168
Published online on: 22 September 2014

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Article

Sox2 is involved in paclitaxel resistance of the prostate cancer cell line PC-3 via the PI3K/Akt pathway

Dong Li, Li-Nan Zhao, Xiu-Lan Zheng, Ping Lin, Feng Lin, Yue Li, Hai‑Feng Zou, Rong-Jun Cui, Hui Chen, Xiao-Guang Yu
Pages: 3169-3176
Published online on: 13 October 2014

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Article

Silencing of the glypican-3 gene affects the biological behavior of human hepatocellular carcinoma cells

Xin-Hui Qi, Di Wu, Hui-Xia Cui, Nan Ma, Jia Su, Yu-Tong Wang, You-Hong Jiang
Pages: 3177-3184
Published online on: 26 September 2014

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Article

Inhibition of glycogen synthase kinase-3β attenuates acute kidney injury in sodium taurocholate‑induced severe acute pancreatitis in rats

Kailiang Zhao, Chen Chen, Qiao Shi, Wenhong Deng, Teng Zuo, Xiaobo He, Tianyi Liu, Liang Zhao, Weixing Wang
Pages: 3185-3192
Published online on: 15 October 2014

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Article

Effects of metformin on FOXM1 expression and on the biological behavior of acute leukemia cell lines

Bing Zhang, Long-Long Liu, Xia Mao, Dong-Hua Zhang
Pages: 3193-3198
Published online on: 13 October 2014

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Article

Matrine improved the function of heart failure in rats via inhibiting apoptosis and blocking β3‑adrenoreceptor/endothelial nitric oxide synthase pathway

Jiangbo Yu, Shusen Yang, Xu Wang, Runtao Gan
Pages: 3199-3204
Published online on: 14 October 2014

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Article

JNK1‑mediated phosphorylation of Smac/DIABLO at the serine 6 residue is functionally linked to its mitochondrial release during TNF‑α­‑induced apoptosis of HeLa cells

Byoungduck Park
Pages: 3205-3210
Published online on: 13 October 2014

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Article

Trichostatin A induces mesenchymal-like morphological change and gene expression but inhibits migration and colony formation in human cancer cells

Rong-Fei Han, Kai Li, Zi-Shan Yang, Zhi-Guo Chen, Wan-Cai Yang
Pages: 3211-3216
Published online on: 23 September 2014

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Article

Comparative study of the protective effects of terfenadine and amiodarone on barium chloride/aconitine-induced ventricular arrhythmias in rats: A potential role of terfenadine

Baoxin Liu, Shuang Li, Yang Su, Mengting Xiong, Yawei Xu
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Published online on: 14 October 2014

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Effects of an adenoviral vector containing a suicide gene fusion on growth characteristics of breast cancer cells

Heng Kong, Chunli Liu, Ting Zhu, Zonghai Huang, Liucheng Yang, Qiang Li
Pages: 3227-3232
Published online on: 14 October 2014

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Investigation of the effect of nocodazole on the PI3K/Akt signaling pathway in COS7 cells

Huaiping Shi, Wujun Wu, Jun Luo
Pages: 3233-3240
Published online on: 14 October 2014

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Esculetin suppresses lipopolysaccharide-induced inflammatory mediators and cytokines by inhibiting nuclear factor-κB translocation in RAW 264.7 macrophages

Su Hyun Hong, Hui-Kyung Jeong, Min Ho Han, Cheol Park, Yung Hyun Choi
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Brain‑derived neurotrophic factor gene polymorphisms are associated with coronary artery disease‑related depression and antidepressant response

Yong‑Qiang Liu, Guo‑Bao Su, Chang‑Hong Duan, Jun‑Hua Wang, Hai‑Mei Liu, Nan Feng, Qing‑Xi Wang, Xu‑En Liu, Jie Zhang
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Published online on: 14 October 2014

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Effects of individual and multiple fatty acids (palmitate, oleate and docosahaexenoic acid) on cell viability and lipid metabolism in LO2 human liver cells

Li Chen, Chunhong Wang, Shaoxin Huang, Bin Gong, Jun Yu, Qun Shi, Guoxun Chen
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Published online on: 18 September 2014

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The protective effect of curcumin against the 19‑kDa Mycobacterium tuberculosis protein-induced inflammation and apoptosis in human macrophages

Mingying Li, Zhenxuan Wu, Wenyi Niu, Yonggan Wan, Ligong Zhang, Guangcan Shi, Xiu'e Xi
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Published online on: 09 October 2014

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Role and mechanisms of microRNA‑503 in drug resistance reversal in HepG2/ADM human hepatocellular carcinoma cells

Dong Wang, Nan Zhang, Yintao Ye, Junqiang Qian, Yu Zhu, Chen Wang
Pages: 3268-3274
Published online on: 22 September 2014

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Inhibition of the p38 MAPK pathway sensitizes human gastric cells to doxorubicin treatment in vitro and in vivo

Wei Tan, Hong-Gang Yu, He-Sheng Luo
Pages: 3275-3281
Published online on: 25 September 2014

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Low-frequency low energy ultrasound combined with microbubbles induces distinct apoptosis of A7r5 cells

Bo Zhang, Hongsheng Zhou, Qian Cheng, Lei Lei, Bing Hu
Pages: 3282-3288
Published online on: 15 October 2014

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Restoration of microRNA‑218 increases cellular chemosensitivity to cervical cancer by inhibiting cell‑cycle progression

Ruofan Dong, Haifeng Qiu, Guiqiang Du, Yuan Wang, Jinjin Yu, Caiping Mao
Pages: 3289-3295
Published online on: 10 October 2014

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Age-dependent tissue expression patterns of Sirt1 in senescence-accelerated mice

Huan Gong, Jing Pang, Yiwen Han, Yang Dai, Dapeng Dai, Jianping Cai, Tie-Mei Zhang
Pages: 3296-3302
Published online on: 15 October 2014

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MicroRNA‑224 is downregulated in mucinous cystic neoplasms of the pancreas and may regulate tumorigenesis by targeting Jagged1

Beibei Zhang, Xiaorong Guo, Jingxi Zhang, Xiao Liu, Xianbao Zhan, Zhaoshen Li
Pages: 3303-3309
Published online on: 15 October 2014

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MicroRNA-16 suppresses epithelial-mesenchymal transition‑related gene expression in human glioma

Qin Wang, Xu Li, Yu Zhu, Ping Yang
Pages: 3310-3314
Published online on: 19 September 2014

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Effects of Asiasari radix on the morphology and viability of mesenchymal stem cells derived from the gingiva

Su‑Hyeon Jeong, Ji‑Eun Lee, Seong-Ho Jin, Youngkyung Ko, Jun-Beom Park
Pages: 3315-3319
Published online on: 03 October 2014

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Quercetin reversed lipopolysaccharide-induced inhibition of osteoblast differentiation through the mitogen‑activated protein kinase pathway in MC3T3-E1 cells

Xin-Chun Wang, Nzhi-Jun Zhao, Chun Guo, Jing-Tao Chen, Jin-Ling Song, Li Gao
Pages: 3320-3326
Published online on: 14 October 2014

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Anti‑fibrotic effects of Acremoniumterricola milleretal mycelium on immunological hepatic fibrosis in rats

Xia Li, Can He, Wang‑Yang Wu, Huan Huang, Wei‑Zu Li, Yan‑Yan Yin
Pages: 3327-3333
Published online on: 30 September 2014

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Inhibition of the invasion and migration of renal carcinoma 786‑o‑si3 cells in vitro and in vivo by Koelreuteria formosana extract

Chin‑Yin Lin, Pei‑Ni Chen, Li‑Sung Hsu, Dong Yih Kuo, Shu‑Chen Chu, Yih‑Shou Hsieh
Pages: 3334-3342
Published online on: 22 September 2014

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USP22 transcriptional activity is negatively regulated by the histone deacetylase inhibitor trichostatin A

Jianjun Xiong, Xiaoyuan Xu, Xiaou Zhou, Jianyun  Liu, Zhen Gong, Ping Wu, Weidong Li
Pages: 3343-3347
Published online on: 15 October 2014

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Bioinformatic mining of kinase inhibitors that regulate autophagy through kinase signaling pathways

Yang Yang, Biao Ma, Ye Jin, Wei Ben, Dandan Zhang, Keping  Jiang, Shujun Feng, Lu Huang, Jianhua Zheng
Pages: 3348-3356
Published online on: 15 October 2014

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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