|
1
|
Tang ZY, Ye SL, Liu YK, et al: A decade’s
studies on metastasis of hepatocellular carcinoma. J Cancer Res
Clin Oncol. 130:187–196. 2004.
|
|
2
|
Schwartz M, Roayaie S and Konstadoulakis
M: Strategies for the management of hepatocellular carcinoma. Nat
Clin Pract Oncol. 4:424–432. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Keating GM and Santoro A: Sorafenib: a
review of its use in advanced hepatocellular carcinoma. Drugs.
69:223–240. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Coulon S, Heindryckx F, Geerts A, et al:
Angiogenesis in chronic liver disease and its complications. Liver
Int. 31:146–162. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kraizer Y, Mawasi N, Seagal J, et al:
Vascular endothelial growth factor and angiopoietin in liver
regeneration. Biochem Biophys Res Commun. 287:209–215. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Schoenleber SJ, Kurtz DM and Talwalkar JA:
Prognostic role of vascular endothelial growth factor in
hepatocellular carcinoma: systematic review and meta-analysis. Br J
Cancer. 100:1385–1392. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Galiè M, Sorrentino C, Montani M, et al:
Mammary carcinoma provides highly tumourigenic and invasive
reactive stromal cells. Carcinogenesis. 26:1868–1878.
2005.PubMed/NCBI
|
|
8
|
Hernandez-Gea V, Toffanin S, Friedman SL
and Llovet JM: Role of the microenvironment in the pathogenesis and
treatment of hepatocellular carcinoma. Gastroenterology.
144:512–527. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Budhu A, Forgues M, Ye QH, et al:
Prediction of venous metastases, recurrence, and prognosis in
hepatocellular carcinoma based on a unique immune response
signature of the liver microenvironment. Cancer Cell. 10:99–111.
2006. View Article : Google Scholar
|
|
10
|
Ribatti D and Vacca A: The role of
microenvironment in tumor angiogenesis. Genes Nutr. 3:29–34. 2008.
View Article : Google Scholar
|
|
11
|
Zhu AX, Duda DG, Sahani DV, et al: HCC and
angiogenesis: possible targets and future directions. Nat Rev Clin
Oncol. 8:292–301. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Guo J and Friedman SL: Hepatic
fibrogenesis. Semin Liver Dis. 27:413–426. 2007. View Article : Google Scholar
|
|
13
|
Friedman SL: Mechanisms of hepatic
fibrogenesis. Gastroenterology. 134:1655–1669. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Enzan H, Himeno H, Iwanmura S, et al:
Alpha-smooth muscle actin-positive perisinusoidal stromal cells in
human hepatocellular carcinoma. Hepatology. 19:895–903. 1994.
|
|
15
|
Thabut D and Shah V: Intrahepatic
angiogenesis and sinusoidal remodeling in chronic liver disease:
new targets for the treatment of portal hypertension? J Hepatol.
53:976–980. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Liao R, Sun TW, Yi Y, et al: Expression of
TREM-1 in hepatic stellate cells and prognostic value in hepatitis
B-related hepatocellular carcinoma. Cancer Sci. 103:984–992. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Amann T, Bataille F, Spruss T, et al:
Activatd hepatic stellate cells promote tumorigenicity of
hepatocellular carcinoma. Cancer Sci. 100:646–653. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Faouzi S, Lepreux S, Bedin C, et al:
Activation of cultured rat hepatic stellate cells by tumoral
hepatocytes. Lab Invest. 79:485–493. 1999.PubMed/NCBI
|
|
19
|
Olaso E, Salado C, Egilegor E, et al:
Proangiogenic role of tumor-activated hepatic stellate cells in
experimental melanoma metastasis. Hepatology. 37:674–685. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Heldin CH: Structural and functional
studies on platelet-derived growth factor. EMBO J. 12:4251–4259.
1992.PubMed/NCBI
|
|
21
|
Watanabe A, Sohail MA, Gomes DA, et al:
Inflammasome-mediated regulation of hepatic stellate cells. Am J
Physiol Gatrointest Liver Physiol. 296:G1248–G1257. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Bandapalli OR, Macher-Goeppinger S,
Schirmacher P, et al: Paracrine signalling in colorectal liver
metastases involving tumor cell-derived PDGF-C and hepatic stellate
cell-derived PAK-2. Clin Exp Metastasis. 29:409–417. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Aleffi S, Navari N, Delogu W, et al:
Mammalian target of rapamycin mediates the angiogenic effects of
leptin in human hepatic stellate cells. Am J Physiol Gastrointest
Liver Physiol. 301:G210–G219. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Jia YL, Shi L, Zhou JN, et al: Epimorphin
promotes human hepatocellular carcinoma invasion and metastasis
through activation of focal adhesion kinase/extracellular
signal-regulated kinase/matrix metalloproteinase-9 axis.
Hepatology. 54:1808–1818. 2011. View Article : Google Scholar
|
|
25
|
Gleadle JM, Ebert BL, Firth JD, et al:
Regulation of angiogenic growth factor expression by hypoxia,
transition metals, and chelating agents. Am J Physiol.
268:C1362–C1368. 1995.PubMed/NCBI
|
|
26
|
Fingas CD, Bronk SF, Werneburg NW, et al:
Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling
in cholangiocarcinoma cells. Hepatology. 54:2076–2088. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Sharma PS, Sharma R and Tyagi T:
VEGF/VEGFR pathway inhibitors as anti-angiogenic agents: present
and future. Curr Cancer Drug Targets. 11:624–653. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zhao W, Zhang L, Yin Z, et al: Activated
hepatic stellate cells promote hepatocellular carcinoma development
in immunocompetent mice. Int J Cancer. 129:2651–2661. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Liao R, Wu H, Yi Y, et al: Clinical
significance and gene expression study of human hepatic stellate
cells in HBV related-hepatocellular carcinoma. J Exp Clin Cancer
Res. 32:22–32. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bowen-Pope DF and Raines EW: History of
discovery: platelet-derived growth factor. Arterioscler Thromb Vasc
Biol. 11:2397–2401. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lee UE and Freidman SL: Mechanisms of
hepatic fibrogenesis. Best Pract Res Clin Gastroenterol.
25:195–206. 2011. View Article : Google Scholar
|
|
32
|
Villanueva A and Llovet JM: Targeted
therapies for hepatocellular carcinoma. Gastroenterology.
140:1410–1426. 2011. View Article : Google Scholar : PubMed/NCBI
|
