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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-2015 Volume 11 Issue 1

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Induced pluripotent stem cell‑based therapies for inherited arrhythmias: Opportunities and challenges involved (Review)

Guoliang Li, Xin He, Chaofeng Sun
Pages: 3-10
Published online on: 16 October 2014

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Review

Pharmacology and phytochemistry of the Nitraria genus (Review)

Qiaohui Du, Hailiang Xin, Cheng Peng
Pages: 11-20
Published online on: 16 October 2014

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Article Open Access

Co-expression analysis of differentially expressed genes in hepatitis C virus-induced hepatocellular carcinoma

Qingfeng Song, Chang Zhao, Shengqiu Ou, Zhibin Meng, Ping Kang, Liwei Fan, Feng Qi, Yilong Ma
Pages: 21-28
Published online on: 17 October 2014

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Article Open Access

Protein‑protein interaction network and mechanism analysis in ischemic stroke

Zhe Quan, Yuan Quan, Bo Wei, Dening Fang, Weidong Yu, Hao Jia, Wei Quan, Yuguang Liu, Qihong Wang
Pages: 29-36
Published online on: 17 October 2014

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Article Open Access

IL‑15 is decreased upon CsA and FK506 treatment of acute rejection following heart transplantation in mice

Zhiyong Yu, Xiaoping Zhou, Songfeng Yu, Haiyang Xie, Shusen Zheng
Pages: 37-42
Published online on: 20 October 2014

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Article Open Access

Association between DNA methylation and multidrug resistance in human glioma SHG‑44 cells

Jin Chen, Zhong‑Ye Xu, Feng Wang
Pages: 43-52
Published online on: 17 October 2014

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Article Open Access

Analysis of metabolic characteristics in a rat model of chronic pancreatitis using high‑resolution magic‑angle spinning nuclear magnetic resonance spectroscopy

Bing Tian, Chao Ma, Jian Wang, Chun‑Shu Pan, Gen‑Jin Yang, Jian‑Ping Lu
Pages: 53-58
Published online on: 22 October 2014

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Article Open Access

Effects of cyclooxygenase‑2 gene silencing on the biological behavior of SKOV3 ovarian cancer cells Retraction in /10.3892/mmr.2021.12346

Feng‑Jun Guo, Jing‑Yan Tian, Yue‑Mei Jin, Ling Wang, Rui‑Qi Yang, Man‑Hua Cui
Pages: 59-66
Published online on: 21 October 2014

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Article Open Access

Systematic profiling of mRNA and miRNA expression in the pancreatic islets of spontaneously diabetic Goto‑Kakizaki rats

Ling‑Qin Zeng, Su‑Bi Wei, Yi‑Min Sun, Wen‑Yan Qin, Jing Cheng, Keith Mitchelson, Lan Xie
Pages: 67-74
Published online on: 21 October 2014

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Article Open Access

Expression analysis of the estrogen receptor target genes in renal cell carcinoma

Zhihong Liu, You Lu, Zonghai He, Libo Chen, Yiping Lu
Pages: 75-82
Published online on: 24 October 2014

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Article Open Access

Octreotide attenuates liver fibrosis by inhibiting hepatic heme oxygenase-1 expression

Shi-Bin Guo, Qing Li, Zhi-Jun Duan, Qiu-Ming Wang, Qin Zhou, Xiao-Yu Sun
Pages: 83-90
Published online on: 22 October 2014

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Article Open Access

Induction of autophagy contributes to cisplatin resistance in human ovarian cancer cells

Lingjie Bao, Melba C. Jaramillo, Zhenbo Zhang, Yunxi Zheng, Ming Yao, Donna D. Zhang, Xiaofang Yi
Pages: 91-98
Published online on: 16 October 2014

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Article Open Access

Melatonin alleviates myosin light chain kinase expression and activity via the mitogen‑activated protein kinase pathway during atherosclerosis in rabbits

Xiaowen Cheng, Yufeng Wan, Yuanhong Xu, Qing Zhou, Yuan Wang, Huaqing Zhu
Pages: 99-104
Published online on: 23 October 2014

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Article Open Access

Ampelopsin induces apoptosis by regulating multiple c‑Myc/S‑phase kinase‑associated protein 2/F‑box and WD repeat‑containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells

Xin‑Mei Chen, Xian‑Biao Xie, Qing Zhao, Fang Wang, Yang Bai, Jun‑Qiang  Yin, Hong Jiang, Xiao‑Lin Xie, Qiang Jia, Gang Huang
Pages: 105-112
Published online on: 21 October 2014

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Article Open Access

In vivo magnetic resonance imaging tracking of transplanted superparamagnetic iron oxide‑labeled bone marrow mesenchymal stem cells in rats with myocardial infarction

Ping Hua, You‑Yu Wang, Li‑Bao Liu, Jia‑Liang Liu, Jian‑Yang Liu, Yan‑Qi Yang, Song‑Ran Yang
Pages: 113-120
Published online on: 15 October 2014

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Article Open Access

Function of interleukin‑17 and ‑35 in the blood of patients with hepatitis B‑related liver cirrhosis

Min Shi, Jue Wei, Jinbin Dong, Wenying Meng, Jiali Ma, Ting Wang, Na Wang, Yugang Wang
Pages: 121-126
Published online on: 16 October 2014

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Article Open Access

Crude extract of Polygonum cuspidatum stimulates immune responses in normal mice by increasing the percentage of Mac‑3‑positive cells and enhancing macrophage phagocytic activity and natural killer cell cytotoxicity

Fu‑Shin Chueh, Jen‑Jyh Lin, Ju‑Hwa Lin, Shu‑Wen Weng, Yi‑Ping Huang, Jing‑Gung Chung
Pages: 127-132
Published online on: 22 October 2014

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Article Open Access

Nesprin‑1 has key roles in the process of mesenchymal stem cell differentiation into cardiomyocyte‑like cells in vivo and in vitro

Wengang Yang, Hui Zheng, Yongyi Wang, Feng Lian, Zhenglei Hu, Song Xue
Pages: 133-142
Published online on: 23 October 2014

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Article Open Access

Hepcidin promotes osteogenic differentiation through the bone morphogenetic protein 2/small mothers against decapentaplegic and mitogen‑activated protein kinase/P38 signaling pathways in mesenchymal stem cells

Huading Lu, Liyi Lian, Dehai Shi, Huiqing Zhao, Yuhu Dai
Pages: 143-150
Published online on: 24 October 2014

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Article Open Access

Resveratrol attenuates intermittent hypoxia‑induced insulin resistance in rats: Involvement of Sirtuin 1 and the phosphatidylinositol‑4,5‑bisphosphate 3‑kinase/AKT pathway

Qiuyan Wang, Xiaohui Sun, Xiaobin Li, Xiang Dong, Peng Li, Li Zhao
Pages: 151-158
Published online on: 23 October 2014

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Article Open Access

Inhibitory effects of C‑type natriuretic peptide on the differentiation of cardiac fibroblasts, and secretion of monocyte chemoattractant protein‑1 and plasminogen activator inhibitor‑1

Zhi‑Qiang Li, Ying‑Long Liu, Gang Li, Bin Li, Yang Liu, Xiao‑Feng Li, Ai‑Jun Liu
Pages: 159-165
Published online on: 23 October 2014

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Article Open Access

Comparison of biological properties of umbilical cord‑derived mesenchymal stem cells from early and late passages: Immunomodulatory ability is enhanced in aged cells

Yong Zhuang, Dong Li, Jinqiu Fu, Qing Shi, Yuanyuan Lu, Xiuli Ju
Pages: 166-174
Published online on: 23 October 2014

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Article Open Access

Functional expression, characterization and application of the human S100A4 protein

Degang Wang, Jianwei Zhang, Ziquan Liu, Yunyun Chen, Chuanxiang Xu, Zhiqing Zhang, Xiaohua Liu, Lei Wu, Xuesi Zhou, Xiangyan Meng, Hua Li, Hongtao Liu, Zifeng Jiang, Tianhui Wang
Pages: 175-181
Published online on: 22 October 2014

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Article Open Access

Reprogramming human adipose tissue stem cells using epidermal keratinocyte extracts

Feng Xie, Xinjie Tang, Qun Zhang, Chenliang Deng
Pages: 182-188
Published online on: 21 October 2014

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Article Open Access

Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress‑associated apoptosis in HeLa cells

Ye Xu, Di Li, Linchuan Zeng, Chunyan Wang, Lili Zhang, Yan Wang, Yang Yu, Shibing Liu, Zhixin Li
Pages: 189-195
Published online on: 16 October 2014

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Article Open Access

Neuronal calcium signaling pathways are associated with the development of epilepsy

Fanxin Meng, Yu You, Zhiliang Liu, Jianming Liu, Hu Ding, Ruxiang Xu
Pages: 196-202
Published online on: 23 October 2014

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Article Open Access

Rocaglamide overcomes tumor necrosis factor‑related apoptosis‑inducing ligand resistance in hepatocellular carcinoma cells by attenuating the inhibition of caspase‑8 through cellular FLICE‑like‑inhibitory protein downregulation

Zhou Luan, Ying He, Fan He, Zhishui Chen
Pages: 203-211
Published online on: 21 October 2014

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Article Open Access

Effect of A disintegrin and metalloproteinase 10 gene silencing on the proliferation, invasion and migration of the human tongue squamous cell carcinoma cell line TCA8113

Yuan Shao, Xiao‑Ying Sha, Yan‑Xia Bai, Fang Quan, Sheng‑Li Wu
Pages: 212-218
Published online on: 21 October 2014

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Article Open Access

Cigarette smoke affects dendritic cell maturation in the small airways of patients with chronic obstructive pulmonary disease

Shi‑Xia Liao, Ting Ding, Xi‑Min Rao, De‑Sheng Sun, Peng‑Peng Sun, Ya‑Jun Wang, Dan‑Dan Fu, Xiao‑Li Liu, Yao Ou‑Yang
Pages: 219-225
Published online on: 23 October 2014

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Article

Single sevoflurane exposure increases methyl‑CpG island binding protein 2 phosphorylation in the hippocampus of developing mice

Xiao‑Dan Han, Min Li, Xiao‑Guang Zhang, Zhang‑Gang Xue, Jing Cang
Pages: 226-230
Published online on: 23 October 2014

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Article

Inhibition of SATB1 expression in regulatory T cells contributes to hepatitis B virus-related chronic liver inflammation

Xue-Fen Li, Li Tian, Yi-Yin Wang, Hai-Shen Kong, Yue-Jiao Dong, Qiao-Yun Zhu, Qin Ni, Yu Chen
Pages: 231-236
Published online on: 23 October 2014

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Article

Electroacupuncture inhibits apoptosis of splenic lymphocytes in traumatized rats through modulation of the TNF-α/NF-κB signaling pathway

Kun Wang, Huaxing Wu, Meng Chi, Jian Zhang, Guonian Wang, Hulun Li
Pages: 237-241
Published online on: 22 October 2014

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Article

Effect of vitamin C administration on hydrogen peroxide‑induced cytotoxicity in periodontal ligament cells

Wenlei Wu, Nanfei Yang, Xiujing Feng, Tingzhe Sun, Pingping Shen, Weibin Sun
Pages: 242-248
Published online on: 21 October 2014

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Article

Knockdown of glucose‑regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability

Tong Lu, Weimin Yang, Zhihua Wang, Zhiquan Hu, Xing Zeng, Chunguang Yang, Ye Wang, Yong Zhang, Fan Li, Zhuo Liu, Dongbiao Wang, Zhangqun Ye
Pages: 249-256
Published online on: 22 October 2014

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Article

Evodiamine sensitizes U87 glioblastoma cells to TRAIL via the death receptor pathway

Muhammad Khan, Yanying Bi, Javed Iqbal Qazi, Limei Fan, Hongwen Gao
Pages: 257-262
Published online on: 20 October 2014

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Article

JNK signaling in hepatocarcinoma cells is associated with the side population upon treatment with anticancer drugs

Jong Bin Kim, Seo-Young Park, Hye Ri Kim, Yeon Hwa Ahn, Hyeon-Gun Jee, Jeong‑Hoon  Lee, Su Jong Yu, Hyo-Suk Lee, Minjong Lee, Jung-Hwan Yoon, Yoon Jun Kim
Pages: 263-268
Published online on: 23 October 2014

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Article

Protective effects of icariin‑mediated SIRT1/FOXO3 signaling pathway on intestinal ischemia/reperfusion‑induced acute lung injury

Feng Zhang, Zhen‑Lu Li, Xiao‑Mei Xu, Yan Hu, Ji‑Hong Yao, Wei Xu, Hui‑Rong Jing, Shu Wang, Shi‑Li Ning, Xiao‑Feng Tian
Pages: 269-276
Published online on: 16 October 2014

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Article

Identification of dysregulated pathways associated with pancreatic cancer by survival analysis

Qiong‑Ying Yuan, Yan‑Ping Gu, Cong‑Jun Wang, Hui Zhang, Xing‑Peng Wang
Pages: 277-282
Published online on: 17 October 2014

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Article

Sorbitol dehydrogenase inhibitor protects the liver from ischemia/reperfusion-induced injury via elevated glycolytic flux and enhanced sirtuin 1 activity

Changhe Zhang, Xiangcheng Li, Qinhong Liu
Pages: 283-288
Published online on: 21 October 2014

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Article

Celecoxib attenuates cachectic events in mice by modulating the expression of vascular endothelial growth factor

Xiaoya Xu, Man Jiang, Ying Zhang, Yuli Bi, Mingyong Han
Pages: 289-294
Published online on: 21 October 2014

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Article

Knockdown of Merm1/Wbscr22 attenuates sensitivity of H460 non‑small cell lung cancer cells to SN‑38 and 5‑FU without alteration to p53 expression levels

Dongmei Yan, Xiaoliang Zheng, Linglan Tu, Jing  Jia, Qin Li, Liyan Cheng, Xiaoju Wang
Pages: 295-302
Published online on: 24 October 2014

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Article

Inhibition of aldose reductase ameliorates diet‑induced nonalcoholic steatohepatitis in mice via modulating the phosphorylation of hepatic peroxisome proliferator-activated receptor α

Tong Chen, Duanyu Shi, Jinfeng Chen, Yanxue Yang, Mengguang Qiu, Wei Wang, Longxin Qiu
Pages: 303-308
Published online on: 21 October 2014

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Article

Smad7 maintains epithelial phenotype of ovarian cancer stem‑like cells and supports tumor colonization by mesenchymal‑epithelial transition

Yiying Li, Wenjia Gong, Xiaoling Ma, Xiaoxi Sun, Hua Jiang, Tong Chen
Pages: 309-316
Published online on: 21 October 2014

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Article

Apoptotic induction of lung adenocarcinoma A549 cells infected by recombinant RVG Newcastle disease virus (rL‑RVG) in vitro

Yulan Yan, Bing Liang, Jin Zhang, Yang Liu, Xuefeng Bu
Pages: 317-326
Published online on: 15 October 2014

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Article

Inhibition of cell proliferation by mild hyperthermia at 43˚C with Paris Saponin I in the lung adenocarcinoma cell line PC‑9

Pengjun Zhao, Hao Jiang, Dan Su, Jianguo Feng, Shenglin Ma, Xinhai Zhu
Pages: 327-332
Published online on: 15 October 2014

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Article

MicroRNA expression profiles associated with acquired gefitinib‑resistance in human lung adenocarcinoma cells

Xiaojun Ge, Limei Zheng, Min Huang, Yonglun Wang, Feng Bi
Pages: 333-340
Published online on: 23 October 2014

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Article

Quercetin enhances adriamycin cytotoxicity through induction of apoptosis and regulation of mitogen‑activated protein kinase/extracellular signal‑regulated kinase/c‑Jun N‑terminal kinase signaling in multidrug‑resistant leukemia K562 cells

Fang‑Yuan Chen, Lan‑Fang Cao, Hai‑Xia Wan, Min‑Yue Zhang, Jia‑Yi Cai, Li‑Jing Shen, Ji‑Hua Zhong, Hua Zhong
Pages: 341-348
Published online on: 21 October 2014

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Article

Low concentrations of trichosanthin induce apoptosis and cell cycle arrest via c‑Jun N‑terminal protein kinase/mitogen‑activated protein kinase activation

Duo Zhang, Bin Chen, Jian Zhou, Lin Zhou, Qing Li, Fei Liu, Kuang‑Yen Chou, Lei Tao, Li‑Ming Lu
Pages: 349-356
Published online on: 23 October 2014

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Article

Total alkaloids of Rubus alceifolius Poir inhibit tumor angiogenesis through suppression of the Notch signaling pathway in a mouse model of hepatocellular carcinoma

Jinyan Zhao, Wei Lin, Zhiyun Cao, Qunchuan Zhuang, Liangpu Zheng, Jun Peng, Zhenfeng Hong
Pages: 357-361
Published online on: 20 October 2014

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Article

Effect of eicosapentaenoic acid on cholesterol gallstone formation in C57BL/6J mice

Soo‑Min Cho, Jin‑A Park, Na‑Hyun Kim, Dong‑Soon Kim, Dan Zhang, Hee Yi, Hee‑Jung Cho, Ja Kyung Kim, Dong Ki Lee, Jin‑Suk Kim, Ho‑Chul Shin
Pages: 362-366
Published online on: 17 October 2014

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Article

Stable transfection into rat bone marrow mesenchymal stem cells by lentivirus‑mediated NT‑3

Yu Gong, Hongfei Wang, Haijun Xia
Pages: 367-373
Published online on: 21 October 2014

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Article

Lycopene attenuates inflammation and apoptosis in post‑myocardial infarction remodeling by inhibiting the nuclear factor‑κB signaling pathway

Qin He, Wei Zhou, Caijin Xiong, Gang Tan, Manhua Chen
Pages: 374-378
Published online on: 16 October 2014

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Article

microRNA‑335 inhibits proliferation, cell‑cycle progression, colony formation, and invasion via targeting PAX6 in breast cancer cells Retraction in /10.3892/mmr.2021.12278

Yuanbiao Meng, Quanqing Zou, Tianqi Liu, Xiaoyong Cai, Yubin Huang, Jinfei Pan
Pages: 379-385
Published online on: 16 October 2014

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Article

Comparative transcriptome analysis between metastatic and non-metastatic gastric cancer reveals potential biomarkers

Dan Feng, Xiaofei Ye, Zhenxin Zhu, Ziran Wei, Qingping Cai, Yajie Wang
Pages: 386-392
Published online on: 20 October 2014

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Article

Selection of reference genes for normalization of quantitative polymerase chain reaction data in mouse models of heart failure

Qiaoling Li, Tingting Hu, Liang Chen, Jiayin Sun, Jun Xie, Rang Li, Biao Xu
Pages: 393-399
Published online on: 23 October 2014

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Article

Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis

Zhiyuan Wu, Bin Liu, Cailing E, Jie Liu, Qingyu Zhang, Juntao  Liu, Nianping Chen, Rongyi Chen, Runzhi Zhu
Pages: 400-404
Published online on: 21 October 2014

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Article

Exosomes from breast cancer cells stimulate proliferation and inhibit apoptosis of CD133+ cancer cells in vitro

Jianhua Shi, Yi Ren, Linlin Zhen, Xiaolan Qiu
Pages: 405-409
Published online on: 22 October 2014

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Article

Icariside II inhibits cell proliferation and induces cell cycle arrest through the ROS‑p38‑p53 signaling pathway in A375 human melanoma cells

Jinfeng Wu, Tao Song, Shuyong Liu, Xiaomei Li, Gang Li, Jinhua Xu
Pages: 410-416
Published online on: 20 October 2014

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Article

Transforming growth factor‑β1‑induced epithelial to mesenchymal transition increases mitochondrial content in the A549 non‑small cell lung cancer cell line

Yunhua Xu, Shun Lu
Pages: 417-421
Published online on: 16 October 2014

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Article

Age-related reduction in calbindin‑D28K expression in the Sprague-Dawley rat lens

Yu Geng, Hao‑Tian Lin, Wan Chen, Zhao‑Chuan Liu, Wu Xiang, Wei‑Rong Chen
Pages: 422-426
Published online on: 16 October 2014

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Article

Screening for serum biomarkers in patients with chronic hepatitis B with hepatitis B surface antigen seroclearance, following pegylated interferon alpha therapy

Zheling Wang, Xiaofei Li, Changhe Shi, Min Zhang, Ru Chen, Wei Wu, Qingshun  Hou, Wei Ke, Tianli Fan, Zirong Wen, Xinjie Hao, Naifang Qu
Pages: 427-433
Published online on: 16 October 2014

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Article

Variations of ABCB4 and ABCB11 genes are associated with primary intrahepatic stones

Shuguang Pan, Xiaowu Li, Peng Jiang, Yan Jiang, Ling Shuai, Yu He, Zhihua Li
Pages: 434-446
Published online on: 15 October 2014

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Article

Detection of human papillomavirus and expression of osteopontin in cervical cancer specimens

Lidao Bao, Qin Si, Lizhou Jia, Xianhua Ren, Ruilian Ma, Yi Wang
Pages: 447-453
Published online on: 15 October 2014

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Article

microRNA‑22 acts as a metastasis suppressor by targeting metadherin in gastric cancer

Yunyun Tang, Xiaoping Liu, Bo Su, Zhiwei Zhang, Xi Zeng, Yanping Lei, Jian Shan, Yongjun Wu, Hailin Tang, Qi Su
Pages: 454-460
Published online on: 16 October 2014

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Article

Effects of topical chondrocyte‑derived extracellular matrix treatment on corneal wound healing, following an alkali burn injury

Jae‑Wook Yang, Soung‑Min Lee, Kyeong‑Hee Oh, Sae‑Gwang  Park, Ii‑Whan Choi, Su‑Kil Seo
Pages: 461-467
Published online on: 21 October 2014

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Article

Cathepsin L is involved in proliferation and invasion of ovarian cancer cells

Luosheng Zhang, Lixia Wei, Guanzhu Shen, Benfu He, Wei Gong, Na Min, Li Zhang, Yuxin Duan, Jingran Xie, Huiyan Luo, Xingwang Gao
Pages: 468-474
Published online on: 20 October 2014

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Article

Aplasia Ras homolog member I expression induces apoptosis in renal cancer cells via the β-catenin signaling pathway

Jian Yu, Chui-Ze Kong, Zhe Zhang, Bo Zhan, Zhen-Ming Jiang
Pages: 475-481
Published online on: 22 October 2014

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Article

Self‑complementary adeno‑associated virus 5‑mediated gene transduction of a novel CD40L mutant confers direct antitumor effects in lung carcinoma

Wei Xu, Yuanyuan Xu, Yunyan Wei, Yaoxi Tan, Hongye Zhao, Weihong Zhao, Jianqing Wu
Pages: 482-488
Published online on: 24 October 2014

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Article

Therapeutic effects of micheliolide on a murine model of rheumatoid arthritis

Hua Xu, Jian Wang, Chijuan Wang, Guoqiang Chang, Yani Lin, Hongju Zhang, Hairui Zhang, Qinghua Li, Tianxiang Pang
Pages: 489-493
Published online on: 24 October 2014

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Article

Characterization by phenotypic and genotypic methods of metallo-β‑lactamase‑producing Pseudomonas aeruginosa isolated from patients with cystic fibrosis

Yongwei Li, Xiaoqian Zhang, Chunxia Wang, Yue Hu, Xiaobin  Niu, Dongxu Pei, Zhiqiang He, Yongyi Bi
Pages: 494-498
Published online on: 16 October 2014

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Article

Anti‑metastatic effect of Smilax china L. extract on MDA‑MB‑231 cells

Kyoung Jin Nho, Jin Mi Chun, Ho Kyoung Kim
Pages: 499-502
Published online on: 17 October 2014

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Article

Fibroblast growth factor 21 enhances cholesterol efflux in THP‑1 macrophage‑derived foam cells

Wei Shang, Xuejing Yu, Honglian Wang, Tielin Chen, Ying Fang, Xianggui  Yang, Puhui Zhou, Fang Nie, Qin Zhou, Jianzhong Zhou
Pages: 503-508
Published online on: 21 October 2014

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Article

GnRH analogues may increase endometrial Hoxa10 promoter methylation and affect endometrial receptivity

Fei Li, Ming Zhang, Yuanzhen Zhang, Teng Liu, Xinlan Qu
Pages: 509-514
Published online on: 16 October 2014

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Article

Increased peroxisome proliferator‑activated receptor γ expression levels in visceral adipose tissue, and serum CCL2 and interleukin-6 levels during visceral adipose tissue accumulation

Thaneswary Yogarajah, Yvonne-Tee Get Bee, Rahmah Noordin, Khoo Boon Yin
Pages: 515-520
Published online on: 16 October 2014

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Article

Sirtuin 1 activation enhances the PGC-1α/mitochondrial antioxidant system pathway in status epilepticus

Sheng-Jun Wang, Xiu-He Zhao, Wen Chen, Ning Bo, Xian-Jin Wang, Zhao-Fu Chi, Wei Wu
Pages: 521-526
Published online on: 21 October 2014

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Article

Oxysophoridine attenuates the injury caused by acute myocardial infarction in rats through anti‑oxidative, anti‑inflammatory and anti‑apoptotic pathways

Cong Meng, Chuan Liu, Yuanwei Liu, Fan Wu
Pages: 527-532
Published online on: 22 October 2014

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Article

microRNA‑155 promotes the proliferation of prostate cancer cells by targeting annexin 7

Zhi‑Kang Cai, Qi Chen, Yan‑Bo Chen, Meng Gu, Da‑Chao Zheng, Juan Zhou, Zhong Wang
Pages: 533-538
Published online on: 22 October 2014

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Article

Hepatic Nrf2 expression is altered by quercetin supplementation in X‑irradiated rats

Raquel Marina, Paquita González, M. Carmen Ferreras, Serafín Costilla, Juan‑Pablo Barrio
Pages: 539-546
Published online on: 22 October 2014

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Article

Sprouty2 protein is downregulated in human squamous cell carcinoma of the head and neck and suppresses cell proliferation in vitro

Chiang-Liang Lin, Wei-Fan Chiang, Chao-Ling Tung, Jeng‑Long Hsieh, Jenn-Ren Hsiao, Wen-Tsung Huang, Li-Yia Feng, Chi-Hua Chang, Shyun-Yeu Liu, Chao-Jung Tsao, Yin-Hsun Feng
Pages: 547-554
Published online on: 20 October 2014

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Article

Inhibition of interleukin‑1β‑stimulated matrix metalloproteinases via the controlled release of interleukin‑1Ra from chitosan microspheres in chondrocytes

Pang‑Hu Zhou, Bei‑Lei Ma, Lei Shi, Ting Xie, Bo Qiu
Pages: 555-560
Published online on: 22 October 2014

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Article

Robinetinidol‑flavone attenuates cholesterol synthesis in hepatoma cells via inhibition of 3‑hydroxy‑3‑methylglutaryl‑coenzyme A reductase

Hai Niu, Yu Chao, Ke Li, Junxiang Li, Weihong Gong, Wen Huang
Pages: 561-566
Published online on: 23 October 2014

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Article

Vanishing lung syndrome in one family: Five cases with a 20-year follow-up

Xichun Gao, Haiying Wang, Kaihong Gou, Baosheng Huang, Dongzhou  Xia, Xiuli Wu, Ming Wei, Shengxi Zheng, Shan Ma, Juanxiang He
Pages: 567-570
Published online on: 16 October 2014

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Article

miR‑143 inhibits cell proliferation by targeting autophagy‑related 2B in non‑small cell lung cancer H1299 cells

Jiali Wei, Zhongliang Ma, Yanli Li, Botao Zhao, Detao Wang, Yan Jin, Youxin Jin
Pages: 571-576
Published online on: 16 October 2014

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Article

Inhibition of lactate dehydrogenase A by microRNA‑34a resensitizes colon cancer cells to 5‑fluorouracil

Xiangyong Li, Haibin Zhao, Xijian Zhou, Lei Song
Pages: 577-582
Published online on: 21 October 2014

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Article

Effects of suppressor of cytokine signaling 1 silencing on human melanoma cell proliferation and interferon‑γ sensitivity

Yang Xu, Wenling Wang, Aihong Gou, Haitao Li, Yanli Tian, Meihua Yao, Rongya Yang
Pages: 583-588
Published online on: 16 October 2014

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Article

Identification of anesthetic‑induced expression changes using DNA microarray

Zaiqi Yang, Mengyuan Zhang, Gongming Wang, Pihong Wei, Shenqiang Gao
Pages: 589-596
Published online on: 16 October 2014

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Article

Silencing ADAM10 inhibits the in vitro and in vivo growth of hepatocellular carcinoma cancer cells

Songyang Liu, Wei Zhang, Kai Liu, Bai Ji, Guangyi Wang
Pages: 597-602
Published online on: 15 October 2014

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Article

Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats

Qi Zhang, Yingying Tan, Nan Zhang, Fanrong Yao
Pages: 603-610
Published online on: 20 October 2014

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Article

Expression profiling of choline and ethanolamine kinases in MCF7, HCT116 and HepG2 cells, and the transcriptional regulation by epigenetic modification

Chua Siang Ling, Khoo Boon Yin, See Too Wei Cun, Few Ling Ling
Pages: 611-618
Published online on: 20 October 2014

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Association between mutations in the gap junction β4 gene and nonsyndromic hearing loss: Genotype‑phenotype correlation patterns

Tung‑Cheng Li, Wen‑Hung Wang, Chuan Li, Jiann‑Jou Yang
Pages: 619-624
Published online on: 21 October 2014

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Article

MicroRNA‑106a confers cisplatin resistance in non‑small cell lung cancer A549 cells by targeting adenosine triphosphatase‑binding cassette A1

Yanxin Ma, Xuenan Li, Song Cheng, Wei Wei, Yaming Li
Pages: 625-632
Published online on: 17 October 2014

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Article

Silencing insulin‑like growth factor‑1 receptor expression inhibits gastric cancer cell proliferation and invasion

Jie Ge, Zihua Chen, Jin Huang, Weijie Yuan, Zhenghao Den, Zhikang Chen
Pages: 633-638
Published online on: 22 October 2014

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Article

Silencing survivin expression inhibits the tumor growth of non‑small‑cell lung cancer cells in vitro and in vivo

Kejian Zhang, Yang Li, Wei Liu, Xinliang Gao, Kewei Zhang
Pages: 639-644
Published online on: 21 October 2014

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Article

Effects of grape seed proanthocyanidin extract on renal injury in type 2 diabetic rats

Lei Bao, Zhaofeng Zhang, Xiaoqian Dai, Ye Ding, Yanfei Jiang, Yujie Li, Yong Li
Pages: 645-652
Published online on: 24 October 2014

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Article

Ardisia crenata extract stimulates melanogenesis in B16F10 melanoma cells through inhibiting ERK1/2 and Akt activation

Cheng Yao, Cheng Long Jin, Jang‑Hee Oh, Inn Gyung Oh, Chi‑Hyun Park, Jin Ho Chung
Pages: 653-657
Published online on: 17 October 2014

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Article

Ectopic expression of B and T lymphocyte attenuator in gastric cancer: A potential independent prognostic factor in patients with gastric cancer

Xing-Yu Feng, Xi-Zhi Wen, Xiao-Jing Tan, Jing-Hui Hou, Ya Ding, Ke‑Feng Wang, Jun Dong, Zhi-Wei Zhou, Ying-Bo Chen, Xiao-Shi Zhang
Pages: 658-664
Published online on: 20 October 2014

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Article

Apigenin inhibits HeLa sphere‑forming cells through inactivation of casein kinase 2α

Jie Liu, Xiao‑Cheng Cao, Qiao Xiao, Mei‑Fang Quan
Pages: 665-669
Published online on: 21 October 2014

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Article

An enzymatically fortified ginseng extract inhibits proliferation and induces apoptosis of KATO3 human gastric cancer cells via modulation of Bax, mTOR, PKB and IκBα

Jeong‑Won Hwang, Young‑Mi Baek, Ik‑Soon Jang, Kyeong Eun Yang, Dong‑Gi Lee, So‑Jung Yoon, Jaerang Rho, Chong‑Kwan Cho, Yeon‑Weol Lee, Ki‑Rok Kwon, Hwa‑Seung Yoo, Jung‑Suk Sung, Shin Kim, Jong‑Wook  Park, Byeong‑Churl Jang, Jong‑Soon Choi
Pages: 670-676
Published online on: 20 October 2014

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Article

Let‑7b binding site polymorphism in the B‑cell lymphoma‑extra large 3'UTR is associated with fluorouracil resistance of hepatocellular carcinoma

Jin Ma, Rui Guo, Ting Wang, Xia Pan, Xiaoyong Lei
Pages: 677-681
Published online on: 17 October 2014

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Article

Effect of microRNA-21 on multidrug resistance reversal in A549/DDP human lung cancer cells

Zuoliang Dong, Li Ren, Li Lin, Jiang Li, Yiwen Huang, Jinhong Li
Pages: 682-690
Published online on: 15 October 2014

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Article

Hypoxia-induced secretion of platelet-derived growth factor‑BB by hepatocellular carcinoma cells increases activated hepatic stellate cell proliferation, migration and expression of vascular endothelial growth factor‑A

Yi Lu, Nan Lin, Zhiju Chen, Ruiyun Xu
Pages: 691-697
Published online on: 17 October 2014

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Article

PACE4 regulates proliferation, migration and invasion in human breast cancer MDA-MB-231 cells

Feifei Wang, Lin Wang, Jihong Pan
Pages: 698-704
Published online on: 17 October 2014

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Article

Paris saponin Ⅶ inhibits metastasis by modulating matrix metalloproteinases in colorectal cancer cells

Lei Fan, Yuhua Li, Yang Sun, Zhenggang Yue, Jin Meng, Xutao Zhang, Rong Zhang, Dian Zhang, Feng Zhang, Qibing Mei
Pages: 705-711
Published online on: 21 October 2014

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Article

Reactive oxygen species‑mediated activation of the Src‑epidermal growth factor receptor‑Akt signaling cascade prevents bortezomib‑induced apoptosis in hepatocellular carcinoma cells Corrigendum in /10.3892/mmr.2025.13677

Jinlin Hou, Anguo Cui, Peiying Song, Hui Hua, Ting Luo, Yangfu Jiang
Pages: 712-718
Published online on: 22 October 2014

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Article

MicroRNA‑210 knockdown contributes to apoptosis caused by oxygen glucose deprivation in PC12 cells

Jie Qiu, Xiao‑Yu Zhou, Xiao‑Guang Zhou, Yong Li, Rui Cheng, Hai‑Ying Liu
Pages: 719-723
Published online on: 15 October 2014

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Article

Pterostilbene attenuates the inflammatory reaction induced by ischemia/reperfusion in rat heart

Min Lv, Kexiang Liu, Shaopeng Fu, Zhe Li, Xia Yu
Pages: 724-728
Published online on: 21 October 2014

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Article

Inhibitory effects of oligochitosan on TNF‑α, IL‑1β and nitric oxide production in lipopolysaccharide‑induced RAW264.7 cells

Jie Zhu, Yuanyuan Zhang, Guoyou Wu, Zhen Xiao, Huanqin Zhou, Xiaomei Yu
Pages: 729-733
Published online on: 15 October 2014

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Article

Interference of Notch 2 inhibits the progression of gliomas and induces cell apoptosis by induction of the cell cycle at the G0/G1 phase

Hui‑Ping Yu, Song‑Tao Qi, Wen‑Feng Feng, Guo‑Zhong  Zhang, He‑Ping Zhang, Jin‑Jun Tian
Pages: 734-738
Published online on: 22 October 2014

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Article

Tumor necrosis factor‑related apoptosis‑inducing ligand induces cytotoxicity specific to osteosarcoma by microRNA response elements

Fei Xiao, Juwu Chen, Chuanju Lian, Pengchao Han, Chaoyang Zhang
Pages: 739-745
Published online on: 20 October 2014

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Article

Pinacidil protects osteoblastic cells against antimycin A-induced oxidative damage

Eun Mi Choi, Woon Won Jung, Kwang Sik Suh
Pages: 746-752
Published online on: 21 October 2014

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September-2026 Volume 34 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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