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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-2015 Volume 11 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Induced pluripotent stem cell‑based therapies for inherited arrhythmias: Opportunities and challenges involved (Review)

Guoliang Li, Xin He, Chaofeng Sun
Pages: 3-10
Published online on: 16 October 2014

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Review

Pharmacology and phytochemistry of the Nitraria genus (Review)

Qiaohui Du, Hailiang Xin, Cheng Peng
Pages: 11-20
Published online on: 16 October 2014

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Article Open Access

Co-expression analysis of differentially expressed genes in hepatitis C virus-induced hepatocellular carcinoma

Qingfeng Song, Chang Zhao, Shengqiu Ou, Zhibin Meng, Ping Kang, Liwei Fan, Feng Qi, Yilong Ma
Pages: 21-28
Published online on: 17 October 2014

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Article Open Access

Protein‑protein interaction network and mechanism analysis in ischemic stroke

Zhe Quan, Yuan Quan, Bo Wei, Dening Fang, Weidong Yu, Hao Jia, Wei Quan, Yuguang Liu, Qihong Wang
Pages: 29-36
Published online on: 17 October 2014

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Article Open Access

IL‑15 is decreased upon CsA and FK506 treatment of acute rejection following heart transplantation in mice

Zhiyong Yu, Xiaoping Zhou, Songfeng Yu, Haiyang Xie, Shusen Zheng
Pages: 37-42
Published online on: 20 October 2014

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Article Open Access

Association between DNA methylation and multidrug resistance in human glioma SHG‑44 cells

Jin Chen, Zhong‑Ye Xu, Feng Wang
Pages: 43-52
Published online on: 17 October 2014

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Article Open Access

Analysis of metabolic characteristics in a rat model of chronic pancreatitis using high‑resolution magic‑angle spinning nuclear magnetic resonance spectroscopy

Bing Tian, Chao Ma, Jian Wang, Chun‑Shu Pan, Gen‑Jin Yang, Jian‑Ping Lu
Pages: 53-58
Published online on: 22 October 2014

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Article Open Access

Effects of cyclooxygenase‑2 gene silencing on the biological behavior of SKOV3 ovarian cancer cells Retraction in /10.3892/mmr.2021.12346

Feng‑Jun Guo, Jing‑Yan Tian, Yue‑Mei Jin, Ling Wang, Rui‑Qi Yang, Man‑Hua Cui
Pages: 59-66
Published online on: 21 October 2014

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Article Open Access

Systematic profiling of mRNA and miRNA expression in the pancreatic islets of spontaneously diabetic Goto‑Kakizaki rats

Ling‑Qin Zeng, Su‑Bi Wei, Yi‑Min Sun, Wen‑Yan Qin, Jing Cheng, Keith Mitchelson, Lan Xie
Pages: 67-74
Published online on: 21 October 2014

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Article Open Access

Expression analysis of the estrogen receptor target genes in renal cell carcinoma

Zhihong Liu, You Lu, Zonghai He, Libo Chen, Yiping Lu
Pages: 75-82
Published online on: 24 October 2014

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Article Open Access

Octreotide attenuates liver fibrosis by inhibiting hepatic heme oxygenase-1 expression

Shi-Bin Guo, Qing Li, Zhi-Jun Duan, Qiu-Ming Wang, Qin Zhou, Xiao-Yu Sun
Pages: 83-90
Published online on: 22 October 2014

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Article Open Access

Induction of autophagy contributes to cisplatin resistance in human ovarian cancer cells

Lingjie Bao, Melba C. Jaramillo, Zhenbo Zhang, Yunxi Zheng, Ming Yao, Donna D. Zhang, Xiaofang Yi
Pages: 91-98
Published online on: 16 October 2014

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Article Open Access

Melatonin alleviates myosin light chain kinase expression and activity via the mitogen‑activated protein kinase pathway during atherosclerosis in rabbits

Xiaowen Cheng, Yufeng Wan, Yuanhong Xu, Qing Zhou, Yuan Wang, Huaqing Zhu
Pages: 99-104
Published online on: 23 October 2014

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Article Open Access

Ampelopsin induces apoptosis by regulating multiple c‑Myc/S‑phase kinase‑associated protein 2/F‑box and WD repeat‑containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells

Xin‑Mei Chen, Xian‑Biao Xie, Qing Zhao, Fang Wang, Yang Bai, Jun‑Qiang  Yin, Hong Jiang, Xiao‑Lin Xie, Qiang Jia, Gang Huang
Pages: 105-112
Published online on: 21 October 2014

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Article Open Access

In vivo magnetic resonance imaging tracking of transplanted superparamagnetic iron oxide‑labeled bone marrow mesenchymal stem cells in rats with myocardial infarction

Ping Hua, You‑Yu Wang, Li‑Bao Liu, Jia‑Liang Liu, Jian‑Yang Liu, Yan‑Qi Yang, Song‑Ran Yang
Pages: 113-120
Published online on: 15 October 2014

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Article Open Access

Function of interleukin‑17 and ‑35 in the blood of patients with hepatitis B‑related liver cirrhosis

Min Shi, Jue Wei, Jinbin Dong, Wenying Meng, Jiali Ma, Ting Wang, Na Wang, Yugang Wang
Pages: 121-126
Published online on: 16 October 2014

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Article Open Access

Crude extract of Polygonum cuspidatum stimulates immune responses in normal mice by increasing the percentage of Mac‑3‑positive cells and enhancing macrophage phagocytic activity and natural killer cell cytotoxicity

Fu‑Shin Chueh, Jen‑Jyh Lin, Ju‑Hwa Lin, Shu‑Wen Weng, Yi‑Ping Huang, Jing‑Gung Chung
Pages: 127-132
Published online on: 22 October 2014

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Article Open Access

Nesprin‑1 has key roles in the process of mesenchymal stem cell differentiation into cardiomyocyte‑like cells in vivo and in vitro

Wengang Yang, Hui Zheng, Yongyi Wang, Feng Lian, Zhenglei Hu, Song Xue
Pages: 133-142
Published online on: 23 October 2014

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Article Open Access

Hepcidin promotes osteogenic differentiation through the bone morphogenetic protein 2/small mothers against decapentaplegic and mitogen‑activated protein kinase/P38 signaling pathways in mesenchymal stem cells

Huading Lu, Liyi Lian, Dehai Shi, Huiqing Zhao, Yuhu Dai
Pages: 143-150
Published online on: 24 October 2014

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Article Open Access

Resveratrol attenuates intermittent hypoxia‑induced insulin resistance in rats: Involvement of Sirtuin 1 and the phosphatidylinositol‑4,5‑bisphosphate 3‑kinase/AKT pathway

Qiuyan Wang, Xiaohui Sun, Xiaobin Li, Xiang Dong, Peng Li, Li Zhao
Pages: 151-158
Published online on: 23 October 2014

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Article Open Access

Inhibitory effects of C‑type natriuretic peptide on the differentiation of cardiac fibroblasts, and secretion of monocyte chemoattractant protein‑1 and plasminogen activator inhibitor‑1

Zhi‑Qiang Li, Ying‑Long Liu, Gang Li, Bin Li, Yang Liu, Xiao‑Feng Li, Ai‑Jun Liu
Pages: 159-165
Published online on: 23 October 2014

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Article Open Access

Comparison of biological properties of umbilical cord‑derived mesenchymal stem cells from early and late passages: Immunomodulatory ability is enhanced in aged cells

Yong Zhuang, Dong Li, Jinqiu Fu, Qing Shi, Yuanyuan Lu, Xiuli Ju
Pages: 166-174
Published online on: 23 October 2014

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Article Open Access

Functional expression, characterization and application of the human S100A4 protein

Degang Wang, Jianwei Zhang, Ziquan Liu, Yunyun Chen, Chuanxiang Xu, Zhiqing Zhang, Xiaohua Liu, Lei Wu, Xuesi Zhou, Xiangyan Meng, Hua Li, Hongtao Liu, Zifeng Jiang, Tianhui Wang
Pages: 175-181
Published online on: 22 October 2014

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Article Open Access

Reprogramming human adipose tissue stem cells using epidermal keratinocyte extracts

Feng Xie, Xinjie Tang, Qun Zhang, Chenliang Deng
Pages: 182-188
Published online on: 21 October 2014

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Article Open Access

Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress‑associated apoptosis in HeLa cells

Ye Xu, Di Li, Linchuan Zeng, Chunyan Wang, Lili Zhang, Yan Wang, Yang Yu, Shibing Liu, Zhixin Li
Pages: 189-195
Published online on: 16 October 2014

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Article Open Access

Neuronal calcium signaling pathways are associated with the development of epilepsy

Fanxin Meng, Yu You, Zhiliang Liu, Jianming Liu, Hu Ding, Ruxiang Xu
Pages: 196-202
Published online on: 23 October 2014

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Article Open Access

Rocaglamide overcomes tumor necrosis factor‑related apoptosis‑inducing ligand resistance in hepatocellular carcinoma cells by attenuating the inhibition of caspase‑8 through cellular FLICE‑like‑inhibitory protein downregulation

Zhou Luan, Ying He, Fan He, Zhishui Chen
Pages: 203-211
Published online on: 21 October 2014

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Article Open Access

Effect of A disintegrin and metalloproteinase 10 gene silencing on the proliferation, invasion and migration of the human tongue squamous cell carcinoma cell line TCA8113

Yuan Shao, Xiao‑Ying Sha, Yan‑Xia Bai, Fang Quan, Sheng‑Li Wu
Pages: 212-218
Published online on: 21 October 2014

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Article Open Access

Cigarette smoke affects dendritic cell maturation in the small airways of patients with chronic obstructive pulmonary disease

Shi‑Xia Liao, Ting Ding, Xi‑Min Rao, De‑Sheng Sun, Peng‑Peng Sun, Ya‑Jun Wang, Dan‑Dan Fu, Xiao‑Li Liu, Yao Ou‑Yang
Pages: 219-225
Published online on: 23 October 2014

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Article

Single sevoflurane exposure increases methyl‑CpG island binding protein 2 phosphorylation in the hippocampus of developing mice

Xiao‑Dan Han, Min Li, Xiao‑Guang Zhang, Zhang‑Gang Xue, Jing Cang
Pages: 226-230
Published online on: 23 October 2014

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Article

Inhibition of SATB1 expression in regulatory T cells contributes to hepatitis B virus-related chronic liver inflammation

Xue-Fen Li, Li Tian, Yi-Yin Wang, Hai-Shen Kong, Yue-Jiao Dong, Qiao-Yun Zhu, Qin Ni, Yu Chen
Pages: 231-236
Published online on: 23 October 2014

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Article

Electroacupuncture inhibits apoptosis of splenic lymphocytes in traumatized rats through modulation of the TNF-α/NF-κB signaling pathway

Kun Wang, Huaxing Wu, Meng Chi, Jian Zhang, Guonian Wang, Hulun Li
Pages: 237-241
Published online on: 22 October 2014

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Article

Effect of vitamin C administration on hydrogen peroxide‑induced cytotoxicity in periodontal ligament cells

Wenlei Wu, Nanfei Yang, Xiujing Feng, Tingzhe Sun, Pingping Shen, Weibin Sun
Pages: 242-248
Published online on: 21 October 2014

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Article

Knockdown of glucose‑regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability

Tong Lu, Weimin Yang, Zhihua Wang, Zhiquan Hu, Xing Zeng, Chunguang Yang, Ye Wang, Yong Zhang, Fan Li, Zhuo Liu, Dongbiao Wang, Zhangqun Ye
Pages: 249-256
Published online on: 22 October 2014

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Article

Evodiamine sensitizes U87 glioblastoma cells to TRAIL via the death receptor pathway

Muhammad Khan, Yanying Bi, Javed Iqbal Qazi, Limei Fan, Hongwen Gao
Pages: 257-262
Published online on: 20 October 2014

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Article

JNK signaling in hepatocarcinoma cells is associated with the side population upon treatment with anticancer drugs

Jong Bin Kim, Seo-Young Park, Hye Ri Kim, Yeon Hwa Ahn, Hyeon-Gun Jee, Jeong‑Hoon  Lee, Su Jong Yu, Hyo-Suk Lee, Minjong Lee, Jung-Hwan Yoon, Yoon Jun Kim
Pages: 263-268
Published online on: 23 October 2014

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Article

Protective effects of icariin‑mediated SIRT1/FOXO3 signaling pathway on intestinal ischemia/reperfusion‑induced acute lung injury

Feng Zhang, Zhen‑Lu Li, Xiao‑Mei Xu, Yan Hu, Ji‑Hong Yao, Wei Xu, Hui‑Rong Jing, Shu Wang, Shi‑Li Ning, Xiao‑Feng Tian
Pages: 269-276
Published online on: 16 October 2014

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Article

Identification of dysregulated pathways associated with pancreatic cancer by survival analysis

Qiong‑Ying Yuan, Yan‑Ping Gu, Cong‑Jun Wang, Hui Zhang, Xing‑Peng Wang
Pages: 277-282
Published online on: 17 October 2014

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Article

Sorbitol dehydrogenase inhibitor protects the liver from ischemia/reperfusion-induced injury via elevated glycolytic flux and enhanced sirtuin 1 activity

Changhe Zhang, Xiangcheng Li, Qinhong Liu
Pages: 283-288
Published online on: 21 October 2014

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Article

Celecoxib attenuates cachectic events in mice by modulating the expression of vascular endothelial growth factor

Xiaoya Xu, Man Jiang, Ying Zhang, Yuli Bi, Mingyong Han
Pages: 289-294
Published online on: 21 October 2014

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Article

Knockdown of Merm1/Wbscr22 attenuates sensitivity of H460 non‑small cell lung cancer cells to SN‑38 and 5‑FU without alteration to p53 expression levels

Dongmei Yan, Xiaoliang Zheng, Linglan Tu, Jing  Jia, Qin Li, Liyan Cheng, Xiaoju Wang
Pages: 295-302
Published online on: 24 October 2014

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Article

Inhibition of aldose reductase ameliorates diet‑induced nonalcoholic steatohepatitis in mice via modulating the phosphorylation of hepatic peroxisome proliferator-activated receptor α

Tong Chen, Duanyu Shi, Jinfeng Chen, Yanxue Yang, Mengguang Qiu, Wei Wang, Longxin Qiu
Pages: 303-308
Published online on: 21 October 2014

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Article

Smad7 maintains epithelial phenotype of ovarian cancer stem‑like cells and supports tumor colonization by mesenchymal‑epithelial transition

Yiying Li, Wenjia Gong, Xiaoling Ma, Xiaoxi Sun, Hua Jiang, Tong Chen
Pages: 309-316
Published online on: 21 October 2014

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Article

Apoptotic induction of lung adenocarcinoma A549 cells infected by recombinant RVG Newcastle disease virus (rL‑RVG) in vitro

Yulan Yan, Bing Liang, Jin Zhang, Yang Liu, Xuefeng Bu
Pages: 317-326
Published online on: 15 October 2014

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Article

Inhibition of cell proliferation by mild hyperthermia at 43˚C with Paris Saponin I in the lung adenocarcinoma cell line PC‑9

Pengjun Zhao, Hao Jiang, Dan Su, Jianguo Feng, Shenglin Ma, Xinhai Zhu
Pages: 327-332
Published online on: 15 October 2014

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Article

MicroRNA expression profiles associated with acquired gefitinib‑resistance in human lung adenocarcinoma cells

Xiaojun Ge, Limei Zheng, Min Huang, Yonglun Wang, Feng Bi
Pages: 333-340
Published online on: 23 October 2014

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Article

Quercetin enhances adriamycin cytotoxicity through induction of apoptosis and regulation of mitogen‑activated protein kinase/extracellular signal‑regulated kinase/c‑Jun N‑terminal kinase signaling in multidrug‑resistant leukemia K562 cells

Fang‑Yuan Chen, Lan‑Fang Cao, Hai‑Xia Wan, Min‑Yue Zhang, Jia‑Yi Cai, Li‑Jing Shen, Ji‑Hua Zhong, Hua Zhong
Pages: 341-348
Published online on: 21 October 2014

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Article

Low concentrations of trichosanthin induce apoptosis and cell cycle arrest via c‑Jun N‑terminal protein kinase/mitogen‑activated protein kinase activation

Duo Zhang, Bin Chen, Jian Zhou, Lin Zhou, Qing Li, Fei Liu, Kuang‑Yen Chou, Lei Tao, Li‑Ming Lu
Pages: 349-356
Published online on: 23 October 2014

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Article

Total alkaloids of Rubus alceifolius Poir inhibit tumor angiogenesis through suppression of the Notch signaling pathway in a mouse model of hepatocellular carcinoma

Jinyan Zhao, Wei Lin, Zhiyun Cao, Qunchuan Zhuang, Liangpu Zheng, Jun Peng, Zhenfeng Hong
Pages: 357-361
Published online on: 20 October 2014

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Article

Effect of eicosapentaenoic acid on cholesterol gallstone formation in C57BL/6J mice

Soo‑Min Cho, Jin‑A Park, Na‑Hyun Kim, Dong‑Soon Kim, Dan Zhang, Hee Yi, Hee‑Jung Cho, Ja Kyung Kim, Dong Ki Lee, Jin‑Suk Kim, Ho‑Chul Shin
Pages: 362-366
Published online on: 17 October 2014

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Article

Stable transfection into rat bone marrow mesenchymal stem cells by lentivirus‑mediated NT‑3

Yu Gong, Hongfei Wang, Haijun Xia
Pages: 367-373
Published online on: 21 October 2014

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Article

Lycopene attenuates inflammation and apoptosis in post‑myocardial infarction remodeling by inhibiting the nuclear factor‑κB signaling pathway

Qin He, Wei Zhou, Caijin Xiong, Gang Tan, Manhua Chen
Pages: 374-378
Published online on: 16 October 2014

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Article

microRNA‑335 inhibits proliferation, cell‑cycle progression, colony formation, and invasion via targeting PAX6 in breast cancer cells Retraction in /10.3892/mmr.2021.12278

Yuanbiao Meng, Quanqing Zou, Tianqi Liu, Xiaoyong Cai, Yubin Huang, Jinfei Pan
Pages: 379-385
Published online on: 16 October 2014

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Article

Comparative transcriptome analysis between metastatic and non-metastatic gastric cancer reveals potential biomarkers

Dan Feng, Xiaofei Ye, Zhenxin Zhu, Ziran Wei, Qingping Cai, Yajie Wang
Pages: 386-392
Published online on: 20 October 2014

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Article

Selection of reference genes for normalization of quantitative polymerase chain reaction data in mouse models of heart failure

Qiaoling Li, Tingting Hu, Liang Chen, Jiayin Sun, Jun Xie, Rang Li, Biao Xu
Pages: 393-399
Published online on: 23 October 2014

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Article

Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis

Zhiyuan Wu, Bin Liu, Cailing E, Jie Liu, Qingyu Zhang, Juntao  Liu, Nianping Chen, Rongyi Chen, Runzhi Zhu
Pages: 400-404
Published online on: 21 October 2014

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Article

Exosomes from breast cancer cells stimulate proliferation and inhibit apoptosis of CD133+ cancer cells in vitro

Jianhua Shi, Yi Ren, Linlin Zhen, Xiaolan Qiu
Pages: 405-409
Published online on: 22 October 2014

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Article

Icariside II inhibits cell proliferation and induces cell cycle arrest through the ROS‑p38‑p53 signaling pathway in A375 human melanoma cells

Jinfeng Wu, Tao Song, Shuyong Liu, Xiaomei Li, Gang Li, Jinhua Xu
Pages: 410-416
Published online on: 20 October 2014

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Article

Transforming growth factor‑β1‑induced epithelial to mesenchymal transition increases mitochondrial content in the A549 non‑small cell lung cancer cell line

Yunhua Xu, Shun Lu
Pages: 417-421
Published online on: 16 October 2014

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Article

Age-related reduction in calbindin‑D28K expression in the Sprague-Dawley rat lens

Yu Geng, Hao‑Tian Lin, Wan Chen, Zhao‑Chuan Liu, Wu Xiang, Wei‑Rong Chen
Pages: 422-426
Published online on: 16 October 2014

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Article

Screening for serum biomarkers in patients with chronic hepatitis B with hepatitis B surface antigen seroclearance, following pegylated interferon alpha therapy

Zheling Wang, Xiaofei Li, Changhe Shi, Min Zhang, Ru Chen, Wei Wu, Qingshun  Hou, Wei Ke, Tianli Fan, Zirong Wen, Xinjie Hao, Naifang Qu
Pages: 427-433
Published online on: 16 October 2014

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Article

Variations of ABCB4 and ABCB11 genes are associated with primary intrahepatic stones

Shuguang Pan, Xiaowu Li, Peng Jiang, Yan Jiang, Ling Shuai, Yu He, Zhihua Li
Pages: 434-446
Published online on: 15 October 2014

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Detection of human papillomavirus and expression of osteopontin in cervical cancer specimens

Lidao Bao, Qin Si, Lizhou Jia, Xianhua Ren, Ruilian Ma, Yi Wang
Pages: 447-453
Published online on: 15 October 2014

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Article

microRNA‑22 acts as a metastasis suppressor by targeting metadherin in gastric cancer

Yunyun Tang, Xiaoping Liu, Bo Su, Zhiwei Zhang, Xi Zeng, Yanping Lei, Jian Shan, Yongjun Wu, Hailin Tang, Qi Su
Pages: 454-460
Published online on: 16 October 2014

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Article

Effects of topical chondrocyte‑derived extracellular matrix treatment on corneal wound healing, following an alkali burn injury

Jae‑Wook Yang, Soung‑Min Lee, Kyeong‑Hee Oh, Sae‑Gwang  Park, Ii‑Whan Choi, Su‑Kil Seo
Pages: 461-467
Published online on: 21 October 2014

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Article

Cathepsin L is involved in proliferation and invasion of ovarian cancer cells

Luosheng Zhang, Lixia Wei, Guanzhu Shen, Benfu He, Wei Gong, Na Min, Li Zhang, Yuxin Duan, Jingran Xie, Huiyan Luo, Xingwang Gao
Pages: 468-474
Published online on: 20 October 2014

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Article

Aplasia Ras homolog member I expression induces apoptosis in renal cancer cells via the β-catenin signaling pathway

Jian Yu, Chui-Ze Kong, Zhe Zhang, Bo Zhan, Zhen-Ming Jiang
Pages: 475-481
Published online on: 22 October 2014

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Article

Self‑complementary adeno‑associated virus 5‑mediated gene transduction of a novel CD40L mutant confers direct antitumor effects in lung carcinoma

Wei Xu, Yuanyuan Xu, Yunyan Wei, Yaoxi Tan, Hongye Zhao, Weihong Zhao, Jianqing Wu
Pages: 482-488
Published online on: 24 October 2014

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Article

Therapeutic effects of micheliolide on a murine model of rheumatoid arthritis

Hua Xu, Jian Wang, Chijuan Wang, Guoqiang Chang, Yani Lin, Hongju Zhang, Hairui Zhang, Qinghua Li, Tianxiang Pang
Pages: 489-493
Published online on: 24 October 2014

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Article

Characterization by phenotypic and genotypic methods of metallo-β‑lactamase‑producing Pseudomonas aeruginosa isolated from patients with cystic fibrosis

Yongwei Li, Xiaoqian Zhang, Chunxia Wang, Yue Hu, Xiaobin  Niu, Dongxu Pei, Zhiqiang He, Yongyi Bi
Pages: 494-498
Published online on: 16 October 2014

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Article

Anti‑metastatic effect of Smilax china L. extract on MDA‑MB‑231 cells

Kyoung Jin Nho, Jin Mi Chun, Ho Kyoung Kim
Pages: 499-502
Published online on: 17 October 2014

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Article

Fibroblast growth factor 21 enhances cholesterol efflux in THP‑1 macrophage‑derived foam cells

Wei Shang, Xuejing Yu, Honglian Wang, Tielin Chen, Ying Fang, Xianggui  Yang, Puhui Zhou, Fang Nie, Qin Zhou, Jianzhong Zhou
Pages: 503-508
Published online on: 21 October 2014

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Article

GnRH analogues may increase endometrial Hoxa10 promoter methylation and affect endometrial receptivity

Fei Li, Ming Zhang, Yuanzhen Zhang, Teng Liu, Xinlan Qu
Pages: 509-514
Published online on: 16 October 2014

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Article

Increased peroxisome proliferator‑activated receptor γ expression levels in visceral adipose tissue, and serum CCL2 and interleukin-6 levels during visceral adipose tissue accumulation

Thaneswary Yogarajah, Yvonne-Tee Get Bee, Rahmah Noordin, Khoo Boon Yin
Pages: 515-520
Published online on: 16 October 2014

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Article

Sirtuin 1 activation enhances the PGC-1α/mitochondrial antioxidant system pathway in status epilepticus

Sheng-Jun Wang, Xiu-He Zhao, Wen Chen, Ning Bo, Xian-Jin Wang, Zhao-Fu Chi, Wei Wu
Pages: 521-526
Published online on: 21 October 2014

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Article

Oxysophoridine attenuates the injury caused by acute myocardial infarction in rats through anti‑oxidative, anti‑inflammatory and anti‑apoptotic pathways

Cong Meng, Chuan Liu, Yuanwei Liu, Fan Wu
Pages: 527-532
Published online on: 22 October 2014

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Article

microRNA‑155 promotes the proliferation of prostate cancer cells by targeting annexin 7

Zhi‑Kang Cai, Qi Chen, Yan‑Bo Chen, Meng Gu, Da‑Chao Zheng, Juan Zhou, Zhong Wang
Pages: 533-538
Published online on: 22 October 2014

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Article

Hepatic Nrf2 expression is altered by quercetin supplementation in X‑irradiated rats

Raquel Marina, Paquita González, M. Carmen Ferreras, Serafín Costilla, Juan‑Pablo Barrio
Pages: 539-546
Published online on: 22 October 2014

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Article

Sprouty2 protein is downregulated in human squamous cell carcinoma of the head and neck and suppresses cell proliferation in vitro

Chiang-Liang Lin, Wei-Fan Chiang, Chao-Ling Tung, Jeng‑Long Hsieh, Jenn-Ren Hsiao, Wen-Tsung Huang, Li-Yia Feng, Chi-Hua Chang, Shyun-Yeu Liu, Chao-Jung Tsao, Yin-Hsun Feng
Pages: 547-554
Published online on: 20 October 2014

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Article

Inhibition of interleukin‑1β‑stimulated matrix metalloproteinases via the controlled release of interleukin‑1Ra from chitosan microspheres in chondrocytes

Pang‑Hu Zhou, Bei‑Lei Ma, Lei Shi, Ting Xie, Bo Qiu
Pages: 555-560
Published online on: 22 October 2014

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Robinetinidol‑flavone attenuates cholesterol synthesis in hepatoma cells via inhibition of 3‑hydroxy‑3‑methylglutaryl‑coenzyme A reductase

Hai Niu, Yu Chao, Ke Li, Junxiang Li, Weihong Gong, Wen Huang
Pages: 561-566
Published online on: 23 October 2014

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Article

Vanishing lung syndrome in one family: Five cases with a 20-year follow-up

Xichun Gao, Haiying Wang, Kaihong Gou, Baosheng Huang, Dongzhou  Xia, Xiuli Wu, Ming Wei, Shengxi Zheng, Shan Ma, Juanxiang He
Pages: 567-570
Published online on: 16 October 2014

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Article

miR‑143 inhibits cell proliferation by targeting autophagy‑related 2B in non‑small cell lung cancer H1299 cells

Jiali Wei, Zhongliang Ma, Yanli Li, Botao Zhao, Detao Wang, Yan Jin, Youxin Jin
Pages: 571-576
Published online on: 16 October 2014

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Inhibition of lactate dehydrogenase A by microRNA‑34a resensitizes colon cancer cells to 5‑fluorouracil

Xiangyong Li, Haibin Zhao, Xijian Zhou, Lei Song
Pages: 577-582
Published online on: 21 October 2014

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Article

Effects of suppressor of cytokine signaling 1 silencing on human melanoma cell proliferation and interferon‑γ sensitivity

Yang Xu, Wenling Wang, Aihong Gou, Haitao Li, Yanli Tian, Meihua Yao, Rongya Yang
Pages: 583-588
Published online on: 16 October 2014

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Article

Identification of anesthetic‑induced expression changes using DNA microarray

Zaiqi Yang, Mengyuan Zhang, Gongming Wang, Pihong Wei, Shenqiang Gao
Pages: 589-596
Published online on: 16 October 2014

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Article

Silencing ADAM10 inhibits the in vitro and in vivo growth of hepatocellular carcinoma cancer cells

Songyang Liu, Wei Zhang, Kai Liu, Bai Ji, Guangyi Wang
Pages: 597-602
Published online on: 15 October 2014

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Article

Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats

Qi Zhang, Yingying Tan, Nan Zhang, Fanrong Yao
Pages: 603-610
Published online on: 20 October 2014

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Article

Expression profiling of choline and ethanolamine kinases in MCF7, HCT116 and HepG2 cells, and the transcriptional regulation by epigenetic modification

Chua Siang Ling, Khoo Boon Yin, See Too Wei Cun, Few Ling Ling
Pages: 611-618
Published online on: 20 October 2014

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Association between mutations in the gap junction β4 gene and nonsyndromic hearing loss: Genotype‑phenotype correlation patterns

Tung‑Cheng Li, Wen‑Hung Wang, Chuan Li, Jiann‑Jou Yang
Pages: 619-624
Published online on: 21 October 2014

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Article

MicroRNA‑106a confers cisplatin resistance in non‑small cell lung cancer A549 cells by targeting adenosine triphosphatase‑binding cassette A1

Yanxin Ma, Xuenan Li, Song Cheng, Wei Wei, Yaming Li
Pages: 625-632
Published online on: 17 October 2014

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Article

Silencing insulin‑like growth factor‑1 receptor expression inhibits gastric cancer cell proliferation and invasion

Jie Ge, Zihua Chen, Jin Huang, Weijie Yuan, Zhenghao Den, Zhikang Chen
Pages: 633-638
Published online on: 22 October 2014

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Article

Silencing survivin expression inhibits the tumor growth of non‑small‑cell lung cancer cells in vitro and in vivo

Kejian Zhang, Yang Li, Wei Liu, Xinliang Gao, Kewei Zhang
Pages: 639-644
Published online on: 21 October 2014

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Article

Effects of grape seed proanthocyanidin extract on renal injury in type 2 diabetic rats

Lei Bao, Zhaofeng Zhang, Xiaoqian Dai, Ye Ding, Yanfei Jiang, Yujie Li, Yong Li
Pages: 645-652
Published online on: 24 October 2014

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Article

Ardisia crenata extract stimulates melanogenesis in B16F10 melanoma cells through inhibiting ERK1/2 and Akt activation

Cheng Yao, Cheng Long Jin, Jang‑Hee Oh, Inn Gyung Oh, Chi‑Hyun Park, Jin Ho Chung
Pages: 653-657
Published online on: 17 October 2014

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Article

Ectopic expression of B and T lymphocyte attenuator in gastric cancer: A potential independent prognostic factor in patients with gastric cancer

Xing-Yu Feng, Xi-Zhi Wen, Xiao-Jing Tan, Jing-Hui Hou, Ya Ding, Ke‑Feng Wang, Jun Dong, Zhi-Wei Zhou, Ying-Bo Chen, Xiao-Shi Zhang
Pages: 658-664
Published online on: 20 October 2014

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Article

Apigenin inhibits HeLa sphere‑forming cells through inactivation of casein kinase 2α

Jie Liu, Xiao‑Cheng Cao, Qiao Xiao, Mei‑Fang Quan
Pages: 665-669
Published online on: 21 October 2014

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Article

An enzymatically fortified ginseng extract inhibits proliferation and induces apoptosis of KATO3 human gastric cancer cells via modulation of Bax, mTOR, PKB and IκBα

Jeong‑Won Hwang, Young‑Mi Baek, Ik‑Soon Jang, Kyeong Eun Yang, Dong‑Gi Lee, So‑Jung Yoon, Jaerang Rho, Chong‑Kwan Cho, Yeon‑Weol Lee, Ki‑Rok Kwon, Hwa‑Seung Yoo, Jung‑Suk Sung, Shin Kim, Jong‑Wook  Park, Byeong‑Churl Jang, Jong‑Soon Choi
Pages: 670-676
Published online on: 20 October 2014

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Article

Let‑7b binding site polymorphism in the B‑cell lymphoma‑extra large 3'UTR is associated with fluorouracil resistance of hepatocellular carcinoma

Jin Ma, Rui Guo, Ting Wang, Xia Pan, Xiaoyong Lei
Pages: 677-681
Published online on: 17 October 2014

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Article

Effect of microRNA-21 on multidrug resistance reversal in A549/DDP human lung cancer cells

Zuoliang Dong, Li Ren, Li Lin, Jiang Li, Yiwen Huang, Jinhong Li
Pages: 682-690
Published online on: 15 October 2014

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Article

Hypoxia-induced secretion of platelet-derived growth factor‑BB by hepatocellular carcinoma cells increases activated hepatic stellate cell proliferation, migration and expression of vascular endothelial growth factor‑A

Yi Lu, Nan Lin, Zhiju Chen, Ruiyun Xu
Pages: 691-697
Published online on: 17 October 2014

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Article

PACE4 regulates proliferation, migration and invasion in human breast cancer MDA-MB-231 cells

Feifei Wang, Lin Wang, Jihong Pan
Pages: 698-704
Published online on: 17 October 2014

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Article

Paris saponin Ⅶ inhibits metastasis by modulating matrix metalloproteinases in colorectal cancer cells

Lei Fan, Yuhua Li, Yang Sun, Zhenggang Yue, Jin Meng, Xutao Zhang, Rong Zhang, Dian Zhang, Feng Zhang, Qibing Mei
Pages: 705-711
Published online on: 21 October 2014

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Article

Reactive oxygen species‑mediated activation of the Src‑epidermal growth factor receptor‑Akt signaling cascade prevents bortezomib‑induced apoptosis in hepatocellular carcinoma cells Corrigendum in /10.3892/mmr.2025.13677

Jinlin Hou, Anguo Cui, Peiying Song, Hui Hua, Ting Luo, Yangfu Jiang
Pages: 712-718
Published online on: 22 October 2014

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Article

MicroRNA‑210 knockdown contributes to apoptosis caused by oxygen glucose deprivation in PC12 cells

Jie Qiu, Xiao‑Yu Zhou, Xiao‑Guang Zhou, Yong Li, Rui Cheng, Hai‑Ying Liu
Pages: 719-723
Published online on: 15 October 2014

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Article

Pterostilbene attenuates the inflammatory reaction induced by ischemia/reperfusion in rat heart

Min Lv, Kexiang Liu, Shaopeng Fu, Zhe Li, Xia Yu
Pages: 724-728
Published online on: 21 October 2014

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Article

Inhibitory effects of oligochitosan on TNF‑α, IL‑1β and nitric oxide production in lipopolysaccharide‑induced RAW264.7 cells

Jie Zhu, Yuanyuan Zhang, Guoyou Wu, Zhen Xiao, Huanqin Zhou, Xiaomei Yu
Pages: 729-733
Published online on: 15 October 2014

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Article

Interference of Notch 2 inhibits the progression of gliomas and induces cell apoptosis by induction of the cell cycle at the G0/G1 phase

Hui‑Ping Yu, Song‑Tao Qi, Wen‑Feng Feng, Guo‑Zhong  Zhang, He‑Ping Zhang, Jin‑Jun Tian
Pages: 734-738
Published online on: 22 October 2014

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Article

Tumor necrosis factor‑related apoptosis‑inducing ligand induces cytotoxicity specific to osteosarcoma by microRNA response elements

Fei Xiao, Juwu Chen, Chuanju Lian, Pengchao Han, Chaoyang Zhang
Pages: 739-745
Published online on: 20 October 2014

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Article

Pinacidil protects osteoblastic cells against antimycin A-induced oxidative damage

Eun Mi Choi, Woon Won Jung, Kwang Sik Suh
Pages: 746-752
Published online on: 21 October 2014

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Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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Review Open Access

R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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Article Open Access

PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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Article Open Access

MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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