|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Xu L, Wang F, Xu XF, et al:
Down-regulation of miR-212 expression by DNA hypermethylation in
human gastric cancer cells. Med Oncol. 28(Suppl 1): S189–S196.
2011. View Article : Google Scholar
|
|
3
|
Lei H, Zou D, Li Z, et al:
MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer
and is regulated by DNA methylation. PLoS One. 8:e603692013.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Tutar L, Tutar E and Tutar Y: MicroRNAs
and Cancer; an Overview. Curr Pharm Biotechnol. 15:430–437. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Taby R and Issa JP: Cancer Epigenetics. CA
Cancer J Clin. 60:376–392. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Dunn BK: Hypomethylation: one side of a
larger picture. Ann NY Acad Sci. 983:28–42. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Frühwald MC and Plass C: Global and
gene-specific methylation patterns in cancer: aspects of tumor
biology and clinical potential. Mol Genet Metab. 75:1–16. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Robertson KD: DNA methylation and human
disease. Nat Rev Genet. 6:597–610. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Takai D and Jones PA: Comprehensive
analysis of CpG islands in human chromosomes 21 and 22. Proc Natl
Acad Sci USA. 99:3740–3745. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Herman JG and Baylin SB: Gene silencing in
cancer in association with promoter hypermethylation. N Engl J Med.
349:2042–2054. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Bird A: DNA methylation patterns and
epigenetic memory. Genes Dev. 16:6–21. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Leonhardt H, Page AW, Weier HU and Bestor
TH: A targeting sequence directs DNA methyltransferase to sites of
DNA replication in mammalian nuclei. Cell. 71:865–873. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Okano M, Bell DW, Haber DA and Li E: DNA
methyltransferases Dnmt3a and Dnmt3b are essential for de novo
methylation and mammalian development. Cell. 99:247–257. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Gowher H, Liebert K, Hermann A, Xu G and
Jeltsch A: Mechanism of stimulation of catalytic activity of Dnmt3A
and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L. J Biol
Chem. 280:13341–13348. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Santi DV, Garrett CE and Barr PJ: On the
mechanism of inhibition of DNA-cytosine methyltransferases by
cytosine analogs. Cell. 33:9–10. 1983. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Zhu A, Xia J, Zuo J, et al: MicroRNA-148a
is silenced by hypermethylation and interacts with DNA
methyltransferase 1 in gastric cancer. Med Oncol. 29:2701–2709.
2012. View Article : Google Scholar
|
|
17
|
Feinberg AP and Vogelstein B:
Hypomethylation distinguishes genes of some human cancers from
their normal counterparts. Nature. 301:89–92. 1983. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Eden A, Gaudet F, Waghmare A and Jaenisch
R: Chromosomal instability and tumors promoted by DNA
hypomethylation. Science. 300:4552003. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Kwon OH, Park JL, Kim M, et al: Aberrant
up-regulation of LAMB3 and LAMC2 by promoter demethylation in
gastric cancer. Biochem Biophys Res Commun. 406:539–545. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Tsai KW, Hu LY, Wu CW, et al: Epigenetic
regulation of miR-196b expression in gastric cancer. Genes
Chromosomes Cancer. 49:969–980. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Costello JF, Frühwald MC, Smiraglia DJ, et
al: Aberrant CpG-island methylation has non-random and
tumour-type-specific patterns. Nat Genet. 24:132–138. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Knudson AG: Two genetic hits (more or
less) to cancer. Nat Rev Cancer. 1:157–162. 2001. View Article : Google Scholar
|
|
23
|
Ross JP, Rand KN and Molloy PL:
Hypomethylation of repeated DNA sequences in cancer. Epigenomics.
2:245–269. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
24
|
Bae JM, Shin SH, Kwon HJ, et al: ALU and
LINE-1 hypomethylation in multistep gastric carcinogenesis and
their prognostic implications. Int J Cancer. 131:1323–1331. 2012.
View Article : Google Scholar
|
|
25
|
Zhao C and Bu X: Promoter methylation of
tumor-related genes in gastric carcinogenesis. Histol Histopathol.
27:1271–1282. 2012.PubMed/NCBI
|
|
26
|
Lee RC, Feinbaum RL and Ambros V: The C.
elegans heterochronic gene lin-4 encodes small RNAs with antisense
complementarity to lin-14. Cell. 75:843–854. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lewis BP, Burge CB and Bartel DP:
Conserved seed pairing, often flanked by adenosines, indicates that
thousands of human genes are microRNA targets. Cell. 120:15–20.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Calin GA, Dumitru CD, Shimizu M, et al:
Frequent deletions and down-regulation of micro-RNA genes miR15 and
miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci
USA. 99:15524–15529. 2002. View Article : Google Scholar
|
|
29
|
Lewis BP, Shih IH, Jones-Rhoades MW,
Bartel DP and Burge CB: Prediction of mammalian microRNA targets.
Cell. 115:787–798. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Calin GA, Sevignani C, Dumitru CD, et al:
Human microRNA genes are frequently located at fragile sites and
genomic regions involved in cancers. Proc Natl Acad Sci USA.
101:2999–3004. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Yamakuchi M, Ferlito M and Lowenstein CJ:
miR-34a repression of SIRT1 regulates apoptosis. Proc Natl Acad Sci
USA. 105:13421–13426. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Mertens-Talcott SU, Chintharlapalli S, Li
X and Safe S: The oncogenic microRNA-27a targets genes that
regulate specificity protein transcription factors and the G2-M
checkpoint in MDA-MB-231 breast cancer cells. Cancer Res.
67:11001–11011. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Liu T, Tang H, Lang Y, Liu M and Li X:
MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by
targeting prohibitin. Cancer Lett. 273:233–242. 2009. View Article : Google Scholar
|
|
34
|
Lai Y, Zhang X, Zhang Z, et al: The
microRNA-27a: ZBTB10-specificity protein pathway is involved in
follicle stimulating hormone-induced VEGF, Cox2 and survivin
expression in ovarian epithelial cancer cells. Int J Oncol.
42:776–784. 2013.
|
|
35
|
Li Q, Zou C, Zou C, et al: MicroRNA-25
functions as a potential tumor suppressor in colon cancer by
targeting Smad7. Cancer Let. 335:168–174. 2013. View Article : Google Scholar
|
|
36
|
Xu X, Chen Z, Zhao X, et al: MicroRNA-25
promotes cell migration and invasion in esophageal squamous cell
carcinoma. Biochem Biophys Res Commun. 421:640–645. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kim YK, Yu J, Han TS, et al: Functional
links between clustered microRNAs: suppression of cell-cycle
inhibitors by microRNA clusters in gastric cancer. Nucleic Acids
Res. 37:1672–1681. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Ji Q, Hao X, Meng Y, et al: Restoration of
tumor suppressor miR-34 inhibits human p53-mutant gastric cancer
tumorspheres. BMC Cancer. 8:2662008. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Xia L, Zhang D, Du R, et al: miR-15b and
miR-16 modulate multidrug resistance by targeting BCL2 in human
gastric cancer cells. Int J Cancer. 123:372–379. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Zhu W, Shan X, Wang T, Shu Y and Liu P:
miR-181b modulates multidrug resistance by targeting BCL2 in human
cancer cell lines. Int J Cancer. 127:2520–2529. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Zhang Z, Li Z, Gao C, et al: miR-21 plays
a pivotal role in gastric cancer pathogenesis and progression. Lab
Invest. 88:1358–1366. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Zhang BG, Li JF, Yu BQ, Zhu ZG, Liu BY and
Yan M: microRNA-21 promotes tumor proliferation and invasion in
gastric cancer by targeting PTEN. Oncol Rep. 27:1019–1026.
2012.PubMed/NCBI
|
|
43
|
Motoyama K, Inoue H, Mimori K, et al:
Clinicopathological and prognostic significance of PDCD4 and
microRNA-21 in human gastric cancer. Int J Oncol. 36:1089–1095.
2010.PubMed/NCBI
|
|
44
|
Deng S, Calin GA, Croce CM, Coukos G and
Zhang L: Mechanisms of microRNA deregulation in human cancer. Cell
Cycle. 7:2643–2646. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ando T, Yoshida T, Enomoto S, et al: DNA
methylation of microRNA genes in gastric mucosae of gastric cancer
patients: its possible involvement in the formation of epigenetic
field defect. Int J Cancer. 124:2367–2374. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Suzuki H, Yamamoto E, Nojima M, et al:
Methylation-associated silencing of microRNA-34b/c in gastric
cancer and its involvement in an epigenetic field defect.
Carcinogenesis. 31:2066–2073. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Suzuki R, Yamamoto E, Nojima M, et al:
Aberrant methylation of microRNA-34b/c is a predictive marker of
metachronous gastric cancer risk. J Gastroentero. 49:1135–1144.
2013. View Article : Google Scholar
|
|
48
|
Hashimoto Y, Akiyama Y, Otsubo T, Shimada
S and Yuasa Y: Involvement of epigenetically silenced microRNA-181c
in gastric carcinogenesis. Carcinogenesis. 31:777–784. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Cui M, Yue L, Fu Y, Yu W, Hou X and Zhang
X: Association of microRNA-181c expression with the progression and
prognosis of human gastric carcinoma. Hepatogastroenterology.
60:961–964. 2013.PubMed/NCBI
|
|
50
|
Balaguer F, Link A, Lozano JJ, et al:
Epigenetic silencing of miR-137 is an early event in colorectal
carcinogenesis. Cancer Res. 70:6609–6618. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Chen Q, Chen X, Zhang M, Fan Q, Luo S and
Cao X: miR-137 is frequently down-regulated in gastric cancer and
is a negative regulator of Cdc42. Dig Dis Sci. 56:2009–2016. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Lehmann U, Hasemeier B, Christgen M, et
al: Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human
breast cancer. J Pathol. 214:17–24. 2008. View Article : Google Scholar
|
|
53
|
Tsai KW, Liao YL, Wu CW, et al: Aberrant
hypermethylation of miR-9 genes in gastric cancer. Epigenetics.
6:1189–1197. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Wan HY, Guo LM, Liu T, Liu M, Li X and
Tang H: Regulation of the transcription factor NF-kappaB1 by
microRNA-9 in human gastric adenocarcinoma. Mol Cancer. 9:162010.
View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Luo H, Zhang H, Zhang Z, et al:
Down-regulated miR-9 and miR-433 in human gastric carcinoma. J Exp
Clin Cancer Res. 28:822009. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Ueda T, Volinia S, Okumura H, et al:
Relation between microRNA expression and progression and prognosis
of gastric cancer: a microRNA expression analysis. Lancet Oncol.
11:136–146. 2010. View Article : Google Scholar
|
|
57
|
Mutze K, Langer R, Schumacher F, et al:
DNA methyltransferase 1 as a predictive biomarker and potential
therapeutic target for chemotherapy in gastric cancer. Eur J
Cancer. 47:1817–1825. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Hanoun N, Delpu Y, Suriawinata AA, et al:
The silencing of microRNA 148a production by DNA hypermethylation
is an early event in pancreatic carcinogenesis. Clin Chem.
56:1107–1118. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Zheng B, Liang L, Wang C, et al:
MicroRNA-148a suppresses tumor cell invasion and metastasis by
downregulating ROCK1 in gastric cancer. Clin Cancer Res.
17:7574–7583. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Li QJ, Zhou L, Yang F, et al: MicroRNA-10b
promotes migration and invasion through CADM1 in human
hepatocellular carcinoma cells. Tumour Biol. 33:1455–1465. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Tian Y, Luo A, Cai Y, et al: MicroRNA-10b
promotes migration and invasion through KLF4 in human esophageal
cancer cell lines. J Biol Chem. 285:7986–7994. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Sasayama T, Nishihara M, Kondoh T, Hosoda
K and Kohmura E: MicroRNA-10b is overexpressed in malignant glioma
and associated with tumor invasive factors, uPAR and RhoC. Int J
Cancer. 125:1407–1413. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Ma L, Teruya-Feldstein J and Weinberg RA:
Tumour invasion and metastasis initiated by microRNA-10b in breast
cancer. Nature. 449:682–688. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Kim K, Lee HC, Park JL, et al: Epigenetic
regulation of microRNA-10b and targeting of oncogenic MAPRE1 in
gastric cancer. Epigenetics. 6:740–751. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Liu M, Yang S, Wang Y, et al: EB1 acts as
an oncogene via activating beta-catenin/TCF pathway to promote
cellular growth and inhibit apoptosis. Mol Carcinog. 48:212–219.
2009. View Article : Google Scholar
|
|
66
|
Deng H, Guo Y, Song H, et al: MicroRNA-195
and microRNA-378 mediate tumor growth suppression by epigenetical
regulation in gastric cancer. Gene. 518:351–359. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Xu T, Zhu Y, Xiong Y, Ge YY, Yun JP and
Zhuang SM: MicroRNA-195 suppresses tumorigenicity and regulates
G1/S transition of human hepatocellular carcinoma cells.
Hepatology. 50:113–121. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Hua Z, Lv Q, Ye W, et al: MiRNA-directed
regulation of VEGF and other angiogenic factors under hypoxia. PLoS
One. 1:e1162006. View Article : Google Scholar
|
|
69
|
Saito Y, Suzuki H, Tsugawa H, et al:
Chromatin remodeling at Alu repeats by epigenetic treatment
activates silenced microRNA-512-5p with downregulation of Mcl-1 in
human gastric cancer cells. Oncogene. 28:2738–2744. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Li P, Chen X, Su L, et al: Epigenetic
silencing of miR-338-3p contributes to tumorigenicity in gastric
cancer by targeting SSX2IP. PLoS One. 8:e667822013. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Bader AG, Brown D and Winkler M: The
promise of microRNA replacement therapy. Cancer Res. 70:7027–7030.
2010. View Article : Google Scholar : PubMed/NCBI
|