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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2015 Volume 11 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Promoter methylated microRNAs: Potential therapeutic targets in gastric cancer (Review)

Xiaoqiang Guo, Jiazeng Xia, Jiang Yan
Pages: 759-765
Published online on: 27 October 2014

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Article Open Access

Analysis of cytosine-adenine repeats in P1 promoter region of IGF-1 gene in peripheral blood cells and cervical tissue samples of females with cervical intraepithelial lesions and squamous cervical cancer

Wojciech Kwasniewski, Anna Gozdzicka‑Jozefiak, Maria Kotarska, Grzegorz Polak, Bartlomiej Barczynski, Justyna Broniarczyk, Witold Nowak, Maria Wolun‑Cholewa, Anna Kwasniewska, Jan Kotarski
Pages: 766-774
Published online on: 10 November 2014

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Article Open Access

Effects of thyroxine and donepezil on hippocampal acetylcholine content, acetylcholinesterase activity, synaptotagmin-1 and SNAP-25 expression in hypothyroid adult rats

Fen Wang, Xianzhong Zeng, Yangbo Zhu, Dan Ning, Junxia Liu, Chunlei Liu, Xuemei Jia, Defa Zhu
Pages: 775-782
Published online on: 30 October 2014

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Article Open Access

Lymphotoxin β receptor activation promotes bladder cancer in a nuclear factor-κB-dependent manner

Mo Shen, Xiuzhi Duan, Ping Zhou, Wu Zhou, Xiuling Wu, Siqi Xu, Yuhua Chen, Zhihua Tao
Pages: 783-790
Published online on: 30 October 2014

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Article Open Access

Triptolide inhibits cell proliferation and tumorigenicity of human neuroblastoma cells

Xiaomin Yan, Xiao-Xue Ke, Hailong Zhao, Mengying Huang, Renjian Hu, Hongjuan Cui
Pages: 791-796
Published online on: 29 October 2014

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Article Open Access

The role of death receptor 3 in the biological behavior of hepatocellular carcinoma cells

You Cheng Zhang, Liu Qing Guo, Xiao Chen, Gen  Nian Wang, Ri Ni, Man Cai Wang, Feng Xian Wei
Pages: 797-804
Published online on: 04 November 2014

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Article Open Access

Astragalus and Paeoniae radix rubra extract inhibits liver fibrosis by modulating the transforming growth factor‑β/Smad pathway in rats

Weijuan Huang, Lin Li, Xiaopeng Tian, Jinjin Yan, Xinzheng Yang, Xinlong Wang, Guozhen Liao, Genquan Qiu
Pages: 805-814
Published online on: 05 November 2014

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Article Open Access

Combination of IGF‑1 gene manipulation and 5‑AZA treatment promotes differentiation of mesenchymal stem cells into cardiomyocyte‑like cells

Jun Li, Kai Zhu, Yulin Wang, Jiayu Zheng, Changfa Guo, Hao Lai, Chunsheng Wang
Pages: 815-820
Published online on: 29 October 2014

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Article Open Access

Near‑infrared fluorescence imaging of prostate cancer using heptamethine carbocyanine dyes

Jianlin Yuan, Xiaomin Yi, Fei Yan, Fuli Wang, Weijun Qin, Guojun  Wu, Xiaojian Yang, Chen Shao, Leland W.K. Chung
Pages: 821-828
Published online on: 29 October 2014

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Article Open Access

Semaphorin 4D induces vaginal epithelial cell apoptosis to control mouse postnatal vaginal tissue remodeling

Takuji Ito, Tao Bai, Tetsuji Tanaka, Kenji Yoshida, Takashi Ueyama, Masayasu Miyajima, Takayuki Negishi, Takahiko Kawasaki, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, Kazunori Yukawa
Pages: 829-836
Published online on: 27 October 2014

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Article Open Access

Downregulation of nitric oxide by electroacupuncture against hypoxic‑ischemic brain damage in rats via nuclear factor‑κB/neuronal nitric oxide synthase

Yichen Liu, Weiguang Li, Linyan Hu, Ying Liu, Baoquan Li, Changqing Sun, Chenggang Zhang, Liping Zou
Pages: 837-842
Published online on: 06 November 2014

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Article Open Access

Identification of differential splicing genes in gliomas using exon expression profiling

Feng Yu, Wei‑Ming Fu
Pages: 843-850
Published online on: 27 October 2014

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Article Open Access

miR‑542‑3p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogh‑like 2

Huazhuang Li, Hongtao Liu, Jingfang Pei, Haiyan Wang, Honglin Lv
Pages: 851-856
Published online on: 27 October 2014

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Article Open Access

Upregulated periostin promotes angiogenesis in keloids through activation of the ERK 1/2 and focal adhesion kinase pathways, as well as the upregulated expression of VEGF and angiopoietin‑1

Zhe Zhang, Fangfei Nie, Xinlei Chen, Zelian Qin, Chunfu Kang, Bin Chen, Jianxun Ma, Bolin Pan, Yongguang Ma
Pages: 857-864
Published online on: 31 October 2014

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Article Open Access

High glucose inhibits receptor activator of nuclear factor‑κB ligand-induced osteoclast differentiation via downregulation of v‑ATPase V0 subunit d2 and dendritic cell‑specific transmembrane protein

Juan Xu, Feng Yue, Jingbo Wang, Li Chen, Wenbo Qi
Pages: 865-870
Published online on: 29 October 2014

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Article Open Access

Ethanol extract of Forsythia suspensa root induces apoptosis of esophageal carcinoma cells via the mitochondrial apoptotic pathway

Lianmei Zhao, Xi Yan, Juan Shi, Fengzhi Ren, Lihua Liu, Shiping Sun, Baoen Shan
Pages: 871-880
Published online on: 05 November 2014

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Article Open Access

Essential role of GATA3 in regulation of differentiation and cell proliferation in SK-N-SH neuroblastoma cells

Hongwei Peng, Xiao-Xue Ke, Renjian Hu, Liqun Yang, Hongjuan Cui, Yuquan Wei
Pages: 881-886
Published online on: 29 October 2014

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Article Open Access

Biological effect of ketamine in urothelial cell lines and global gene expression analysis in the bladders of ketamine‑injected mice

Cheng‑Huang Shen, Shou‑Tsung Wang, Ying‑Ray Lee, Shiau‑Yuan Liu, Yi‑Zhen Li, Jiann‑Der Wu, Yi‑Ju Chen, Yi‑Wen Liu
Pages: 887-895
Published online on: 30 October 2014

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Article Open Access

Effect of galectin-3 on the behavior of Eca‑109 human esophageal cancer cells

Ning Liang, Xiaoming Song, Jian Xie, Deguo Xu, Fengjun Liu, Xinshuang  Yu, Yuan Tian, Zhen Liu, Lili Qiao, Jiandong Zhang
Pages: 896-902
Published online on: 05 November 2014

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Article Open Access

A study of the ultrasound-targeted microbubble destruction based triplex-forming oligodexinucleotide delivery system to inhibit tissue factor expression

Weihua Liang, Weiwei Zhang, Shifu Zhao, Qianning Li, Yiming Yang, Hua Liang, Rongchuan Ceng
Pages: 903-909
Published online on: 30 October 2014

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Article Open Access

Effect of immunosuppression on the human mesangial cell cycle

Xiaoshuang Zhou, Biruh Workeneh, Zhaoyong Hu, Rongshan Li
Pages: 910-916
Published online on: 04 November 2014

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Article Open Access

Role of cysteine‑rich angiogenic inducer 61 in fibroblast‑like synovial cell proliferation and invasion in rheumatoid arthritis Corrigendum in /10.3892/mmr.2022.12901

Li‑Gang Jie, Run‑Yue Huang, Wei‑Feng Sun, Song Wei, Yong‑Liang Chu, Qing‑Chun Huang, Hong‑Yan Du
Pages: 917-923
Published online on: 27 October 2014

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Article Open Access

Ephrin type‑A receptor 2 regulates sensitivity to paclitaxel in nasopharyngeal carcinoma via the phosphoinositide 3‑kinase/Akt signalling pathway

Yunyun Wang, Yong Liu, Guo Li, Zhongwu Su, Shuling Ren, Pingqing  Tan, Xin Zhang, Yuanzheng Qiu, Yongquan Tian
Pages: 924-930
Published online on: 29 October 2014

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Article Open Access

Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines Retraction in /10.3892/mmr.2021.12080

Li Wang, Jianzhong Wu, Jianwei Lu, Rong Ma, Dawei Sun, Jinhai Tang
Pages: 931-939
Published online on: 30 October 2014

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Article Open Access

Ginsenoside‑Rg5 induces apoptosis and DNA damage in human cervical cancer cells

Li‑Dan Liang, Tao He, Ting‑Wei Du, Yong‑Gang Fan, Dian‑Sen Chen, Yan Wang
Pages: 940-946
Published online on: 30 October 2014

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Article Open Access

Skewed T-helper (Th)1/2- and Th17/T regulatory‑cell balances in patients with renal cell carcinoma

Long Li, Cheng Yang, Zitong Zhao, Bin Xu, Minghuan Zheng, Chao Zhang, Zhihui Min, Jianming Guo, Ruiming Rong
Pages: 947-953
Published online on: 27 October 2014

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Article Open Access

Tracking of mesenchymal stem cells labeled with gadolinium diethylenetriamine pentaacetic acid by 7T magnetic resonance imaging in a model of cerebral ischemia

Kuan Geng, Zhong Xian Yang, Dexiao Huang, Meizi Yi, Yanlong  Jia, Gen Yan, Xiaofang Cheng, Renhua Wu
Pages: 954-960
Published online on: 29 October 2014

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Article Open Access

A disintegrin and metalloproteinase 17 mRNA and protein expression in esophageal squamous cell carcinoma, as well as its clinicopathological factors and prognosis

Hong‑Bin Liu, Qi‑Chang Yang, Yi Shen, Yan Zhu, Xiao‑Juan Zhang, Hao Chen
Pages: 961-967
Published online on: 29 October 2014

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Article Open Access

Arsenic sulfide as a potential anti‑cancer drug

Wenping Ding, Lian Zhang, Sungkyoung Kim, Wei Tian, Yingying Tong, Jianwen Liu, Yong Ma, Siyu Chen
Pages: 968-974
Published online on: 03 November 2014

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Article Open Access

Self‑assembled monolayers of alkanethiolates on surface chemistry groups in osteosarcoma cells

Ying‑Hu Deng, Li‑Hua Li, Jin He, Mei Li, Yu Zhang, Xiu‑Mei Wang, Fu‑Zhai Cui, Hong Xia
Pages: 975-981
Published online on: 06 November 2014

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Article Open Access

TAZ promotes epithelial to mesenchymal transition via the upregulation of connective tissue growth factor expression in neuroblastoma cells

Qiang Wang, Zhilin Xu, Qun An, Dapeng Jiang, Long Wang, Bingxue Liang, Zhaozhu Li
Pages: 982-988
Published online on: 30 October 2014

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Article

Reprogramming rat embryonic fibroblasts into induced pluripotent stem cells using transposon vectors and their chondrogenic differentiation in vitro

Jiakuan Ye, Junyi Hong, Fusheng Ye
Pages: 989-994
Published online on: 27 October 2014

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Article

Oscillatory potentials in electroretinogram as an early marker of visual abnormalities in vitamin A deficiency

Dai Kakiuchi, Taisuke Uehara, Motohiro Shiotani, Kyoko Nakano‑Ito, Akiyoshi Suganuma, Toyohiko Aoki, Kazuo Tsukidate, Kohei Sawada
Pages: 995-1003
Published online on: 03 November 2014

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Article

Apigenin inhibits migration and invasion via modulation of epithelial mesenchymal transition in prostate cancer

Yi Zhu, Jian Wu, Shiqi Li, Xiao Wang, Zhen Liang, Xianglai Xu, Xin Xu, Zhenghui Hu, Yiwei Lin, Hong Chen, Jie Qin, Qiqi Mao, Liping Xie
Pages: 1004-1008
Published online on: 29 October 2014

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Article

Neutralizing antibodies respond to a bivalent dengue DNA vaccine or/and a recombinant bivalent antigen

Zhi‑Shan Zhang, Yu‑Wei Weng, Hai‑Long Huang, Jian‑Ming Zhang, Yan‑Sheng Yan
Pages: 1009-1016
Published online on: 03 November 2014

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Article

microRNA-34a and microRNA-34c promote the activation of human hepatic stellate cells by targeting peroxisome proliferator-activated receptor γ

Xiaofei Li, Yongxin Chen, Shuang Wu, Jinke He, Lianqing Lou, Weiwei Ye, Jinhe Wang
Pages: 1017-1024
Published online on: 03 November 2014

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Article

Reduced β‑2‑glycoprotein І inhibits hypoxia‑induced retinal angiogenesis in neonatal mice through the vascular endothelial growth factor pathway

Hongyan Liu, Saijun Zhou, Gareth Denyer, Zhenxing Meng, Rui Chen, Lin Lv, Chunjun Li, Demin Yu, Pei Yu
Pages: 1025-1030
Published online on: 05 November 2014

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Article

Activation of S1P2 receptor, a possible mechanism of inhibition of adipogenic differentiation by sphingosine 1‑phosphate

Myung‑Hee Moon, Jae‑Kyo Jeong, Sang‑Youel Park
Pages: 1031-1036
Published online on: 29 October 2014

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Article

Expression of hepatocyte growth factor in breast cancer and its effect on prognosis and sensitivity to chemotherapy

Hua Yang, Chongjian Zhang, Shude Cui
Pages: 1037-1042
Published online on: 29 October 2014

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Article

Increased immunoreactivity of c‑Fos in the spinal cord of the aged mouse and dog

Ji Hyeon Ahn, Myoung Chul Shin, Joon Ha Park, In Hye Kim, Jae‑Chul Lee, Bing Chun Yan, In Koo Hwang, Seung Myung Moon, Ji Yun Ahn, Taek Geun Ohk, Tae Hun Lee, Jun Hwi Cho, Hyung‑Cheul Shin, Moo‑Ho Won
Pages: 1043-1048
Published online on: 29 October 2014

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Article

Interleukin‑21 promotes the development of ulcerative colitis and regulates the proliferation and secretion of follicular T helper cells in the colitides microenvironment

Jing Yu, Songbing He, Pengfei Liu, You Hu, Lei Wang, Xu Wang, Ye Han, Xinguo Zhu
Pages: 1049-1056
Published online on: 30 October 2014

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Article

GABAA receptor overexpression in the lateral hypothalamic area attenuates gastric ischemia‑reperfusion injury in rats

Lin Gao, Tao Zhu, Guilin Xie, Xiangxin Lou, Shibao Li, Yan Zhou, Zhenxu Deng, Dechang Chu, Jiyu Lou, Dongshu Du
Pages: 1057-1062
Published online on: 29 October 2014

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Article

Isolation and purification of oligopeptides from Ruditapes philippinarum and its inhibition on the growth of DU‑145 cells in vitro

Zuisu Yang, Yuqin Zhao, Haiqiang Yan, Lv Xu, Guofang Ding, Di Yu, Yu Sun
Pages: 1063-1068
Published online on: 27 October 2014

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Article

Interaction between the human cytomegalovirus‑encoded UL142 and cellular Snapin proteins

Chang Liu, Ying Qi, Yanping Ma, Rong He, Zhengrong  Sun, Yujing Huang, Yaohua Ji, Qiang Ruan
Pages: 1069-1072
Published online on: 31 October 2014

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Article

Visfatin: An adipokine activator of rat hepatic stellate cells

Ning‑Lin Liang, Ruoting Men, Yongjun Zhu, Cong Yuan, Yan Wei, Xiaojing Liu, Li Yang
Pages: 1073-1078
Published online on: 29 October 2014

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Article

Bioinformatic analysis of microRNA expression in Parkinson's disease

Bin Hao, Xin Chen, Dongwei Dai, Chao Zou, Xi Wu, Jianchun Chen
Pages: 1079-1084
Published online on: 03 November 2014

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Article

Combination of quercetin and hyperoside inhibits prostate cancer cell growth and metastasis via regulation of microRNA‑21

Feng‑Qiang Yang, Min Liu, Wei Li, Jian‑Ping Che, Guang‑Chun Wang, Jun‑Hua Zheng
Pages: 1085-1092
Published online on: 29 October 2014

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Article

Simvastatin enhances oxidized‑low density lipoprotein‑induced macrophage autophagy and attenuates lipid aggregation

Baojun Huang, Mengxing Jin, Hai Yan, Yanwei Cheng, Dake Huang, Songcheng Ying, Linjie Zhang
Pages: 1093-1098
Published online on: 27 October 2014

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Article

Enhanced downregulation of transforming growth factor‑β2 in rat retinal pigment epithelium cells by adeno‑associated virus‑mediated ribonucleic acid interference combined with ultrasound or microbubbles

Hongli Li, Caifeng Wan, Lianfang Du, Fenghua Li
Pages: 1099-1104
Published online on: 03 November 2014

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Article

Co‑culture with human fetal epidermal keratinocytes promotes proliferation and migration of human fetal and adult dermal fibroblasts

Zhe Wang, Xiaoyu Liu, Dianbao Zhang, Xiliang Wang, Feng Zhao, Ping Shi, Xining Pang
Pages: 1105-1110
Published online on: 29 October 2014

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Article

Synergetic effects of hBMSCs and hPCs in osteogenic differentiation and their capacity in the repair of critical-sized femoral condyle defects

Daoyun Chen, Hao Shen, Yaohua He, Yunsu Chen, Qi Wang, Jianxi Lu, Yao Jiang
Pages: 1111-1119
Published online on: 06 November 2014

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Article

Resveratrol attenuates inflammation in the rat heart subjected to ischemia-reperfusion: Role of the TLR4/NF-κB signaling pathway

Jingbo Li, Chunyang Xie, Junli Zhuang, Hali Li, Ye Yao, Changgang Shao, Haiyang Wang
Pages: 1120-1126
Published online on: 14 November 2014

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Article

Association between the mitochondrial DNA 4977 common deletion in the hair shaft and hearing loss in presbycusis

Hong Liu, Yuechen Han, Shuai Wang, Haibo Wang
Pages: 1127-1131
Published online on: 06 November 2014

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Article

Determining the neuroprotective effects of dextromethorphan in lipopolysaccharide‑stimulated BV2 microglia

Wenjing Cheng, Yunhong Li, Xiaolin Hou, Bin Bai, Fan  Li, Feijia  Ding, Jiao Ma, Nan Zhang, Ying Shen, Yin Wang
Pages: 1132-1138
Published online on: 27 October 2014

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Article

Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-κB-dependent matrix metalloproteinase-9 expression Corrigendum in /10.3892/mmr.2019.9833

Zanjing Zhai, Xinhua Qu, Haowei Li, Zhengxiao Ouyang, Wei Yan, Guangwang Liu, Xuqiang Liu, Qiming Fan, Tingting Tang, Kerong Dai, An Qin
Pages: 1139-1145
Published online on: 05 November 2014

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Article

Differentiation of Schwann‑like cells from human umbilical cord blood mesenchymal stem cells in vitro

Yu‑Zhou Xiao, Sheng Wang
Pages: 1146-1152
Published online on: 03 November 2014

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Article

RhoV mediates apoptosis of RAW264.7 macrophages caused by osteoclast differentiation

Ruilong Song, Xuezhong Liu, Jiaqiao Zhu, Qian Gao, Qichao Wang, Jiaming Zhang, Dong Wang, Laiyang Cheng, Di  Hu, Yan Yuan, Jianhong Gu, Zongping Liu
Pages: 1153-1159
Published online on: 30 October 2014

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Article

Synergic effect between 5‑fluorouracil and celecoxib on hypoxic gastric cancer cells Corrigendum in /10.3892/mmr.2021.12332

Xiao‑Qian Zhang, Xiu‑E Sun, Wen‑Dong Liu, Yu‑Guang Feng, Hong‑Mei Zhang, Li‑Hong Shi, Xiu‑Ning Sun, Yan‑Qing Li, Zhi‑Xing Gao
Pages: 1160-1166
Published online on: 27 October 2014

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Article

Blockage of RelB expression by gene silencing enhances the radiosensitivity of androgen‑independent prostate cancer cells

Heng‑Cheng Zhu, Tao Qiu, Chao Dan, Xiu‑Heng Liu, Chun‑Hai Hu
Pages: 1167-1173
Published online on: 04 November 2014

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Article

Morphine protects SH-SY5Y human neuroblastoma cells against Dickkopf1-induced apoptosis

Kun-Peng Wang, Yu Bai, Jian Wang, Jin-Zhen Zhang
Pages: 1174-1180
Published online on: 31 October 2014

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Article

Nemo‑like kinase expression predicts poor survival in colorectal cancer

Jingbo Chen, Yunwei Han, Xiaoqian Zhao, Mingyu Yang, Bo Liu, Xiangpeng Xi, Xiaolin Xu, Tiejun Liang, Lijian Xia
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Article

Interactions of connexin 43 and aquaporin-4 in the formation of glioma-induced brain edema

Gang Li, Xiaozhi Liu, Zhenlin Liu, Zhiguo Su
Pages: 1188-1194
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Article

Chondrogenic differentiation of human adipose‑derived stem cells using microcarrier and bioreactor combination technique

Hongjun Kang, Shibi Lu, Jiang Peng, Qiang Yang, Shuyun Liu, Li Zhang, Jingxiang Huang, Xiang Sui, Bin Zhao, Aiyuan Wang, Wenjing Xu, Quanyi Guo, Qing Song
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Published online on: 30 October 2014

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Article

MicroRNA-96 promotes the proliferation of colorectal cancer cells and targets tumor protein p53 inducible nuclear protein 1, forkhead box protein O1 (FOXO1) and FOXO3a

Feng Gao, Wenhui Wang
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Article

Effects of engineered conserved dopamine neurotrophic factor-expressing bone marrow stromal cells on dopaminergic neurons following 6-OHDA administrations

Jiaming Mei, Chaoshi Niu
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Article

p53 suppresses stress-induced cellular senescence via regulation of autophagy under the deprivation of serum Retraction in /10.3892/mmr.2020.11474

Xinbing Sui, Yong Fang, Haizhou Lou, Kaifeng Wang, Yu Zheng, Fang Lou, Wei Jin, Yinghua Xu, Wei Chen, Hongming Pan, Xian Wang, Weidong Han
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Differentiation of human amniotic epithelial cells into Schwann‑like cells via indirect co‑culture with Schwann cells in vitro

Shuang Zhu, Jiachun Li, Qingtang Zhu, Ting Dai, Bo  He, Xiang  Zhou, Jianping Xiang, Xiaolin Liu
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Protection of cultured human hepatocytes from hydrogen peroxide‑induced apoptosis by relaxin‑3

Xiao Ma, Su Han, Wei Zhang, Yu‑Jing Fan, Ming‑Na Liu, Ai‑Yun Liu, Bing‑Rong Liu
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Article

Screening of human chromosome 21 genes in the dorsolateral prefrontal cortex of individuals with Down syndrome

Xiang‑Dong Kong, Ning Liu, Xue‑Ju Xu, Zhen‑Hua Zhao, Miao Jiang
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N‑Myc downstream‑regulated gene 2 suppresses proliferation and induces oncosis of OS‑RC‑2 human renal cancer cells

Huihua Liao, Zhou Wu, Xingduan Huang, Zhiqing Qiu, Huien Wu
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Simvastatin attenuates angiotensin II‑induced inflammation and oxidative stress in human mesangial cells

Fengxiang Zhang, Dapeng Sun, Junjiang Chen, Ning  Guan, Xiaochuan Huo, Huanjiu Xi
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G-patch domain containing 2, a gene highly expressed in testes, inhibits nuclear factor-κB and cell proliferation

Fen Hu, Lixia Gou, Qing Liu, Wendian Zhang, Mengmeng Luo, Xiujun Zhang
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Effects of tetraspanin CD151 inhibition on A549 human lung adenocarcinoma cells

Pengcheng Li, Hesong Zeng, Jin Qin, Yuanlin Zou, Dan  Peng, Houjuan Zuo, Zhengxiang Liu
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Article

Integrin αv promotes proliferation by activating ERK 1/2 in the human lung cancer cell line A549

Shijie Fu, Limin Fan, Xufeng Pan, Yifeng Sun, Heng Zhao
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GRIM‑19‑mediated Stat3 activation is a determinant for resveratrol‑induced proliferation and cytotoxicity in cervical tumor‑derived cell lines

Yong‑Guang Li, Hong‑Juan Xia, Jian‑Ping Tao, Ping Xin, Ming‑Ya Liu, Jing‑Bo Li, Wei Zhu, Meng Wei
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Identification of miR‑125a‑5p as a tumor suppressor of renal cell carcinoma, regulating cellular proliferation, migration and apoptosis

Duqun Chen, Yifan Li, Zhengming Su, Zuhu Yu, Wenshui Yu, Yuchi Li, Yaoting Gui, Shangqi Yang, Yongqing Lai
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Effects of antiviral therapy on the cellular immune response in patients with chronic hepatitis B

Guangcheng Luo, Xia Feng, Yanxiang Huang, Tingting Yi, Dongsheng  Wang, Xiaolan Guo, Huiping Yan, Guoyuan Zhang
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Article

Biological characteristics of Taxol‑resistant ovarian cancer cells and reversal of Taxol resistance by adenovirus expressing p53

Qun Liu, Rui Sui, Ruirui Li, Jinwei Miao, Jian Liu
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Article

Autologous platelet‑rich plasma promotes proliferation and chondrogenic differentiation of adipose‑derived stem cells

Ji Shen, Qingfeng Gao, Yao Zhang, Yaohua He
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Identification of optimal reference genes for quantitative PCR studies on human mesenchymal stem cells

Xiuying Li, Qiwei Yang, Jinping Bai, Yanyan Yang, Lingzhi Zhong, Yimin Wang
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Purification of polysaccharides from Cordyceps militaris and their anti‑hypoxic effect

Yuan Dong, Shuang Hu, Chungang Liu, Qingfan Meng, Jia Song, Jiahui  Lu, Yingkun Cheng, Chaohui Gao, Yan Liu, Di Wang, Lirong Teng
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Article

Overexpression of DEK gene is correlated with poor prognosis in hepatocellular carcinoma

Huo‑Chun Yi, Ya‑Li Liu, Pan You, Jin‑Shui Pan, Jian‑Yan Zhou, Zhen‑Jin Liu, Zhong-Ying Zhang
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Metabolomics study on model rats of chronic obstructive pulmonary disease treated with Bu‑Fei Jian‑Pi

Jiansheng Li, Liping Yang, Ya Li, Yange Tian, Suyun Li, Suli Jiang, Ying Wang, Xinmin Li
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miR‑107 promotes the erythroid differentiation of leukemia cells via the downregulation of Cacna2d1

Jie Ruan, Xinguang Liu, Xingdong Xiong, Chunlong Zhang, Jiangbin  Li, Huiling Zheng, Chirong Huang, Qiong Shi, Yaguang Weng
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A simple method of catalase purification for the undergraduate experimental course

Qian Chen, Meng Cheng, Yinnan Wang, Ming Yao, Yongchun Chen, Yuan Gao, Wenyuan Ding
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V‑set and transmembrane domain‑containing 1 is silenced in human hematopoietic malignancy cell lines with promoter methylation and has inhibitory effects on cell growth

Ting Li, Xiaohuan Guo, Wenyan Wang, Xiaoning  Mo, Pingzhang Wang, Wenling Han
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LY294002 inhibits the malignant phenotype of osteosarcoma cells by modulating the phosphatidylinositol 3‑kinase/Akt/fatty acid synthase signaling pathway in vitro

Yang Zhou, Liang Bo Zhu, Ai Fen Peng, Tao Fang Wang, Xin Hua Long, Song Gao, Rong Ping Zhou, Zhi Li Liu
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Lycopene protects against apoptosis in hypoxia/reoxygenation‑induced H9C2 myocardioblast cells through increased autophagy

Fei Chen, Ze‑Wei Sun, Li‑Fang Ye, Guo‑Sheng Fu, Yun Mou, Shen‑Jiang Hu
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Chloroquine inhibits MGC803 gastric cancer cell migration via the Toll-like receptor 9/nuclear factor kappa B signaling pathway

Yanli Zhang, Yunhong Li, Yalan Li, Rui Li, Yajun Ma, Hao Wang, Yin Wang
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Synergistic protective effects of escin and low‑dose glucocorticoids against vascular endothelial growth factor‑induced blood‑retinal barrier breakdown in retinal pigment epithelial and umbilical vein endothelial cells

Fenglan Zhang, Xuejing Man, Huajun Yu, Limei Liu, Yuanbin Li
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MicroRNA‑144 suppresses tumorigenesis of hepatocellular carcinoma by targeting AKT3

Ying Ma, Xing‑Guo She, Ying‑Zi Ming, Qi‑Quan Wan, Qi‑Fa Ye
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Potential regulatory molecules in the human trabecular meshwork of patients with glaucoma: Immunohistochemical profile of a number of inflammatory cytokines

Samanta Taurone, Guido Ripandelli, Elena Pacella, Enrica Bianchi, Andrea Maria Plateroti, Stefania De Vito, Pasquale Plateroti, Francesca Romana Grippaudo, Carlo Cavallotti, Marco Artico
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Article

Quantitative proteomic analysis of Down syndrome in the umbilical cord blood using iTRAQ

Weiguo Sui, Ruohan Zhang, Jiejing Chen, Huiyan He, Zhenzhen Cui, Minglin Ou, Wuxian Li, Suwen Qi, Jingli Wen, Xiuhua Lin, Yong Dai
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microRNA-338-3p functions as a tumor suppressor in human non‑small‑cell lung carcinoma and targets Ras-related protein 14

Jiangtao Sun, Xiaoshang Feng, Shegan Gao, Zhongyue Xiao
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Gel electrophoretic separation of proteins from cultured neuroendocrine tumor cell lines

Natalia Miękus, Ilona Olędzka, Alina Plenis, Zofia Woźniak, Anna Lewczuk, Patrycja Koszałka, Barbara Seroczyńska, Tomasz Bączek
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Article

Emodin has a protective effect in cases of severe acute pancreatitis via inhibition of nuclear factor‑κB activation resulting in antioxidation

Wei‑Yan Yao, Yu‑Fen Zhou, Ai‑Hua Qian, Yong‑Ping Zhang, Min‑Min Qiao, Zu‑Kang Zhai, Yao‑Zong Yuan, Song‑Lin Yang
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Article

Gene expression profiling of histologically normal breast tissue in females with human epidermal growth factor receptor 2‑positive breast cancer

Pavol Zubor, Jozef Hatok, Petra Moricova, Ivana Kapustova, Karol Kajo, Andrea Mendelova, Monika Kmetova Sivonova, Jan Danko
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Article

Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion

Bo Ra You, Hye Rim Shin, Bo Ram Han, Suhn Hee Kim, Woo Hyun Park
Pages: 1428-1434
Published online on: 31 October 2014

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Article

Downregulation of microRNA-429 inhibits cell proliferation by targeting p27Kip1 in human prostate cancer cells

Yongri Ouyang, Ping Gao, Baoyi Zhu, Xi Chen, Fang  Lin, Xi  Wang, Junxia Wei, Huizhong Zhang
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Article

Human age‑related cataracts: Epigenetic suppression of the nuclear factor erythroid 2‑related factor 2‑mediated antioxidant system

Yunxia Gao, Ying Yan, Tingfen Huang
Pages: 1442-1447
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Article

Protective effect of 3-n-butylphthalide against hypertensive nephropathy in spontaneously hypertensive rats

Jun Zhu, Yantao Zhang, Changhai Yang
Pages: 1448-1454
Published online on: 27 October 2014

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Article

Hiwi downregulation, mediated by shRNA, reduces the proliferation and migration of human hepatocellular carcinoma cells

Yingjun Xie, Yongsheng Yang, Degang Ji, Dan Zhang, Xiaoxiao Yao, Xuewen Zhang
Pages: 1455-1461
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Article

Association of CYP3A4/5 genotypes and expression with the survival of patients with neuroblastoma

Mohamad H. Darwish, Roula A. Farah, Ghada N. Farhat, Paul‑Henri N. Torbey, Fatima A. Ghandour, Noha A. Bejjani‑Doueihy, Hassan R. Dhaini
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microRNA‑99a inhibits cell proliferation, colony formation ability, migration and invasion by targeting fibroblast growth factor receptor 3 in prostate cancer

Deyao Wu, Yunfeng Zhou, Huixing Pan, Ping Qu, Jian Zhou
Pages: 1469-1475
Published online on: 27 October 2014

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Article

Salvia miltiorrhiza injection restores apoptosis of fibroblast-like synoviocytes cultured with serum from patients with rheumatoid arthritis

Qing-Song Liu, Xiong-Yan Luo, Hong Jiang, Yan Xing, Ming‑Hui Yang, Guo-Hua Yuan, Zhong Tang, He Wang
Pages: 1476-1482
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Article

Overexpression of the chimeric plasmin-resistant VEGF165/VEGF183 (132-158) protein in murine breast cancer induces distinct vascular patterning adjacent to tumors and retarded tumor growth Corrigendum in /mmr/11/5/4010

Hui-Yong Zhang, Bing-Lin Fan, Xin-Sheng Wu, Ling‑Min  Mu, Wen-Feng Wang, Wu-Ling Zhu
Pages: 1483-1489
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Article

HIF‑1 signaling pathway involving iNOS, COX‑2 and caspase‑9 mediates the neuroprotection provided by erythropoietin in the retina of chronic ocular hypertension rats

Dongmei Gui, Yanfeng Li, Xiaolong Chen, Dianwen Gao, Yang Yang, Xun Li
Pages: 1490-1496
Published online on: 04 November 2014

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Article

Novel IL-6-secreting γδT cells increased in patients with atherosclerotic cerebral infarction

Youdi He, Ning Ma, Chen Xing, Xiaoqian Wang, He Xiao, Mingke Zheng, Gencheng Han, Guojiang Chen, Chunmei Hou, Beifen Shen, Yan Li, Zhenyu Jiang, Renxi Wang, Wenli Hu
Pages: 1497-1503
Published online on: 29 October 2014

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Article

Heat shock protein 27 phosphorylation in the proliferation and apoptosis of human umbilical vein endothelial cells induced by high glucose through the phosphoinositide 3‑kinase/Akt and extracellular signal‑regulated kinase 1/2 pathways

Hai‑Feng Chen, Shu‑Juan Liu, Gang Chen
Pages: 1504-1508
Published online on: 06 November 2014

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Article

Mitochondrial aldehyde dehydrogenase activity protects against lipopolysaccharide‑induced cardiac dysfunction in rats

Ying Hu, Jin‑Bin Yan, Ming‑Zhi Zheng, Xing‑Hui Song, Lin‑Lin Wang, Yue‑Liang Shen, Ying‑Ying Chen
Pages: 1509-1515
Published online on: 29 October 2014

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Article

Estrogen receptor β agonist enhances temozolomide sensitivity of glioma cells by inhibiting PI3K/AKT/mTOR pathway

Xiaoyang Liu, Libo Wang, Jiajun Chen, Qi Ling, Hongfei Wang, Shilin Li, Liming Li, Shuping Yang, Mingying Xia, Ling Jing
Pages: 1516-1522
Published online on: 29 October 2014

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Article

Exercise pre‑conditioning alleviates brain damage via excitatory amino acid transporter 2 and extracellular signal‑regulated kinase 1/2 following ischemic stroke in rats

Xiao Wang, Min Zhang, Rui Feng, Wen‑Bin Li, Shi‑Qing Ren, Feng Zhang
Pages: 1523-1527
Published online on: 31 October 2014

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Article

Increased serum amyloid A and its association with autoantibodies, acute phase reactants and disease activity in patients with rheumatoid arthritis

Chen Shen, Xu‑Guo Sun, Na Liu, Yun Mu, Cheng‑Cheng  Hong, Wei Wei, Fang Zheng
Pages: 1528-1534
Published online on: 29 October 2014

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Article

Thalidomide combined with irradiation alters the activity of two proteases

Ece Şimşek, Esra Aydemir, Aylin Fidan Korcum, Kayahan Fişkın
Pages: 1535-1541
Published online on: 31 October 2014

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Activated P2X7 receptor upregulates the expression levels of NALP3 in P388D1 murine macrophage‑like cells

Zhe Chen, Hongfei Jin, Yahui Hou, Bo Wang, Chunlin Chen, Ziyi Yang, Dongbing Ding, Yunfei Zuo, Shuangyi Ren
Pages: 1542-1546
Published online on: 27 October 2014

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Yan Shi, Shu-Ai Hou
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Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
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Rui Li, Lianxin Wang
Article Number: 37
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Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
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Article Number: 20
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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

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Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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