|
1
|
Petersen KF and Shulman GI: Etiology of
insulin resistance. Am J Med. 119:S10–16. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hirabara SM, Silveira LR, Abdulkader F,
Carvalho CR, Procopio J and Curi R: Time-dependent effects of fatty
acids on skeletal muscle metabolism. J Cell Physiol. 210:7–15.
2007. View Article : Google Scholar
|
|
3
|
McGarry JD: Banting lecture 2001:
dysregulation of fatty acid metabolism in the etiology of type 2
diabetes. Diabetes. 51:7–18. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Silveira LR, Fiamoncini J, Hirabara SM, et
al: Updating the effects of fatty acids on skeletal muscle. J Cell
Physiol. 217:1–12. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Brehm A, Krssak M, Schmid AI, Nowotny P,
Waldhausl W and Roden M: Increased lipid availability impairs
insulin-stimulated ATP synthesis in human skeletal muscle.
Diabetes. 55:136–140. 2006. View Article : Google Scholar
|
|
6
|
Chanseaume E, Malpuech-Brugére C, Patrac
V, et al: Diets high in sugar, fat, and energy induce muscle
type-specific adaptations in mitochondrial functions in rats. J
Nutr. 136:2194–2200. 2006.PubMed/NCBI
|
|
7
|
Schrauwen P, Schrauwen-Hinderling V, Hoeks
J and Hesselink MK: Mitochondrial dysfunction and lipotoxicity.
Biochim Biophys Acta. 1801:266–271. 2010. View Article : Google Scholar
|
|
8
|
Schrauwen-Hinderling VB, Hesselink MK,
Schrauwen P and Kooi ME: Intramyocellular lipid content in human
skeletal muscle. Obesity (Silver Spring). 14:357–367. 2006.
View Article : Google Scholar
|
|
9
|
Koves TR, Ussher JR, Noland RC, et al:
Mitochondrial overload and incomplete fatty acid oxidation
contribute to skeletal muscle insulin resistance. Cell Metab.
7:45–56. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Guo H, Ingolia NT, Weissman JS and Bartel
DP: Mammalian microRNAs predominantly act to decrease target mRNA
levels. Nature. 466:835–840. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ferland-McCollough D, Ozanne SE, Siddle K,
Willis AE and Bushell M: The involvement of microRNAs in Type 2
diabetes. Biochemical Society Transactions. 38:1565–1570. 2010.
View Article : Google Scholar
|
|
12
|
Poy MN, Spranger M and Stoffel M:
microRNAs and the regulation of glucose and lipid metabolism.
Diabetes Obes Metab. 9(Suppl 2): 67–73. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Gallagher IJ, Scheele C, Keller P, et al:
Integration of microRNA changes in vivo identifies novel molecular
features of muscle insulin resistance in type 2 diabetes. Genome
Med. 2:92010. View
Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chen GQ, Lian WJ, Wang GM, Wang S, Yang YQ
and Zhao ZW: Altered microRNA expression in skeletal muscle results
from high-fat diet-induced insulin resistance in mice. Mol Med
Report. 5:1362–1368. 2012.
|
|
15
|
Zhang Y, Yang L, Gao YF, et al:
MicroRNA-106b induces mitochondrial dysfunction and insulin
resistance in C2C12 myotubes by targeting mitofusin-2. Mol Cell
Endocrinol. 381:230–240. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Shi CM, Wang YM, Zhang CM, et al:
Knockdown of NYGGF4 (PID1) rescues insulin resistance and
mitochondrial dysfunction induced by FCCP in 3T3-L1 adipocytes.
Mitochondrion. 12:600–606. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Houstis N, Rosen ED and Lander ES:
Reactive oxygen species have a causal role in multiple forms of
insulin resistance. Nature. 440:944–948. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Soriano FX, Liesa M, Bach D, Chan DC,
Palacin M and Zorzano A: Evidence for a mitochondrial regulatory
pathway defined by peroxisome proliferator-activated receptor-gamma
coactivator-1 alpha, estrogen-related receptor-alpha, and
mitofusin-2. Diabetes. 55:1783–1791. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zorzano A: Regulation of mitofusin-2
expression in skeletal muscle. Appl Physiol Nutr Metab. 34:433–439.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
20
|
Russell AP, Gastaldi G, Bobbioni-Harsch E,
et al: Lipid peroxidation in skeletal muscle of obese as compared
to endurance-trained humans: a case of good vs. bad lipids? FEBS
Lett. 551:104–106. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Schrauwen P, Mensink M, Schaart G, et al:
Reduced skeletal muscle uncoupling protein-3 content in prediabetic
subjects and type 2 diabetic patients: restoration by rosiglitazone
treatment. J Clin Endocrinol Metab. 91:1520–1525. 2006. View Article : Google Scholar
|
|
22
|
Jheng HF, Tsai PJ, Guo SM, et al:
Mitochondrial fission contributes to mitochondrial dysfunction and
insulin resistance in skeletal muscle. Mol Cell Biol. 32:309–319.
2012. View Article : Google Scholar :
|
|
23
|
Liesa M, Palacín M and Zorzano A:
Mitochondrial dynamics in mammalian health and disease. Physiol
Rev. 89:799–845. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Bach D, Naon D, Pich S, et al: Expression
of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human
skeletal muscle: effects of type 2 diabetes, obesity, weight loss,
and the regulatory role of tumor necrosis factor alpha and
interleukin-6. Diabetes. 54:2685–2693. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Mingrone G, Manco M, Calvani M, Castagneto
M, Naon D and Zorzano A: Could the low level of expression of the
gene encoding skeletal muscle mitofusin-2 account for the metabolic
inflexibility of obesity? Diabetologia. 48:2108–2114. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sebastian D, Hernandez-Alvarez MI, Segales
J, et al: Mitofusin-2 (Mfn2) links mitochondrial and endoplasmic
reticulum function with insulin signaling and is essential for
normal glucose homeostasis. Proc Natl Acad Sci USA. 109:5523–5528.
2012. View Article : Google Scholar
|
|
27
|
Gao X, Zhao XL, Zhu YH, et al:
Tetramethylpyrazine protects palmitate-induced oxidative damage and
mitochondrial dysfunction in C2C12 myotubes. Life Sci. 88:803–809.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Vielhaber S, Debska-Vielhaber G, Peeva V,
et al: Mitofusin-2 mutations affect mitochondrial function by
mitochondrial DNA depletion. Acta Neuropathol. 125:245–256. 2013.
View Article : Google Scholar
|
|
29
|
Lally JS, Herbst EA, Matravadia S, et al:
Over-expressing mitofusin-2 in healthy mature mammalian skeletal
muscle does not alter mitochondrial bioenergetics. PLoS One.
8:e556602013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zorzano A, Hernández-Alvarez MI, Palacin M
and Mingrone G: Alterations in the mitochondrial regulatory
pathways constituted by the nuclear co-factors PGC-1alpha or
PGC-1beta and mitofusin 2 in skeletal muscle in type 2 diabetes.
Biochim Biophys Acta. 1797:1028–1033. 2010. View Article : Google Scholar : PubMed/NCBI
|
