|
1
|
Vestbo J, Hurd SS, Agusti AG, et al:
Global strategy for the diagnosis, management, and prevention of
chronic obstructive pulmonary disease: GOLD executive summary. Am J
Respir Crit Care Med. 187:347–365. 2013. View Article : Google Scholar
|
|
2
|
Wright JL, Postma DS, Kerstjens HA, Timens
W, Whittaker P and Churg A: Airway remodeling in the smoke exposed
guinea pig model. Inhal Toxicol. 19:915–923. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Cosio M, Ghezzo H, Hogg JC, et al: The
relations between structural changes in small airways and
pulmonary-function tests. N Engl J Med. 298:1277–1281. 1978.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Hasegawa M, Nasuhara Y, Onodera Y, et al:
Airflow limitation and airway dimensions in chronic obstructive
pulmonary disease. Am J Respir Crit Care Med. 173:1309–1315. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
D’hulst AI, Vermaelen KY, Brusselle GG, et
al: Time course of cigarette smoke-induced pulmonary inflammation
in mice. Eur Respir J. 26:204–213. 2005. View Article : Google Scholar
|
|
6
|
Simmons MS, Connett JE, Nides MA, et al:
Smoking reduction and the rate of decline in FEV(1): results from
the Lung Health Study. Eur Respir J. 25:1011–1017. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Willemse BW, Postma DS, Timens W and ten
Hacken NH: The impact of smoking cessation on respiratory symptoms,
lung function, airway hyperresponsiveness and inflammation. Eur
Respir J. 23:464–476. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Willemse BW, ten Hacken NH, Rutgers B,
Lesman-Leegte IG, Postma DS and Timens W: Effect of 1-year smoking
cessation on airway inflammation in COPD and asymptomatic smokers.
Eur Respir J. 26:835–845. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Gamble E, Grootendorst DC, Hattotuwa K, et
al: Airway mucosal inflammation in COPD is similar in smokers and
ex-smokers: a pooled analysis. Eur Respir J. 30:467–471. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Lapperre TS, Postma DS, Gosman MM, et al:
Relation between duration of smoking cessation and bronchial
inflammation in COPD. Thorax. 61:115–121. 2006. View Article : Google Scholar
|
|
11
|
Braber S, Henricks PA, Nijkamp FP,
Kraneveld AD and Folkerts G: Inflammatory changes in the airways of
mice caused by cigarette smoke exposure are only partially reversed
after smoking cessation. Respir Res. 11:992010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Wang Z, Zhang JN, Hu XF, et al: Effects of
pentoxifylline on Wnt/β-catenin signaling in mice chronically
exposed to cigarette smoke. Chin Med J (Engl). 123:2688–2694.
2010.
|
|
13
|
Zhang JN, Wang Z, Shi W, et al: Mechanism
responsible for pu lmonary fibrosis induced by concomitant chronic
smoke exposure and pentoxifylline administration. Chin J
Pathophysiol (Chin). 25:333–337. 2009.
|
|
14
|
Biselli PJ, Lopes FD, Moriya HT, et al:
Short-term exposure of mice to cigarette smoke and/or residual oil
fly ash produces proximal airspace enlargments and airway
epithelium remodeling. Braz J Med Biol Res. 44:460–468. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Bracke KR, Dentener MA, Papakonstantinou
E, et al: Enhanced deposition of low-molecular-weight hyaluronan in
lungs of cigarette smoke-exposed mice. Am J Respir Cell Mol Biol.
42:753–761. 2010. View Article : Google Scholar
|
|
16
|
Tønnesen P, Carrozzi L, Fagerström K, et
al: Smoking cessation in patients with respiratory diseases: a high
priority, integral component of therapy. Eur Respir J. 29:390–417.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kotz D, Wesseling G, Huibers MJ and van
Schayck OC: Efficacy of confronting smokers with airflow limitation
for smoking cessation. Eur Respir J. 33:754–762. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Demoor T, Bracke KR, Dupont LL, et al: The
role of ChemR23 in the induction and resolution of cigarette
smoke-induced inflammation. J Immunol. 186:5457–5467. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Hautamaki RD, Kobayashi DK, Senior RM and
Shapiro SD: Requirement for macrophage elastase for cigarette
smoke-induced emphysema in mice. Science. 277:2002–2004. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Shapiro SD: The macrophage in chronic
obstructive pulmonary disease. Am J Respir Crit Care Med.
160:S29–S32. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Bitterman PB, Wewers MD, Rennard SI,
Adelberg S and Crystal RG: Modulation of alveolar macrophage-driven
fibroblast proliferation by alternative macrophage mediators. J
Clin Invest. 77:700–708. 1986. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Houghton AM, Quintero PA, Perkins DL, et
al: Elastin fragments drive disease progression in a murine model
of emphysema. J Clin Invest. 116:753–759. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Venet A, Hance AJ, Saltini C, Robinson BW
and Crystal RG: Enhanced alveolar macrophage-mediated
antigen-induced T-lymphocyte proliferation in sarcoidosis. J Clin
Invest. 75:293–301. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Shapiro SD and Ingenito EP: The
pathogenesis of chronic obstructive pulmonary disease: advances in
the past 100 years. Am J Respir Cell Mol Biol. 32:367–372. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hogg JC, Chu F, Utokaparch S, et al: The
nature of small-airway obstruction in chronic obstructive pulmonary
disease. N Engl J ed. 350:2645–2653. 2004. View Article : Google Scholar
|
|
26
|
Finkelstein R, Fraser RS, Ghezzo H and
Cosio MG: Alveolar inflammation and its relation to emphysema in
smokers. Am J Respir Crit Care Med. 152:1666–1672. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Shapiro SD, Kobayashi DK and Ley TJ:
Cloning and characterization of a unique elastolytic
metalloproteinase produced by human alveolar macrophages. J Biol
Chem. 268:23824–23829. 1993.PubMed/NCBI
|
|
28
|
Chandler S, Cossins J, Lury J and Wells G:
Macrophage metalloelastase degrades matrix and myelin proteins and
processes a tumour necrosis factor-alpha fusion protein. Biochem
Biophys Res Commun. 228:421–429. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Gronski TJ Jr, Martin RL, Kobayashi DK, et
al: Hydrolysis of a broad spectrum of extracellular matrix proteins
by human macrophage elastase. J Biol Chem. 272:12189–12194. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
England KA, Price AP, Tram KV, Shapiro SD,
Blazar BR and Panoskaltsis-Mortari A: Evidence for early fibrosis
and increased airway resistance in bone marrow transplant recipient
mice deficient in MMP12. Am J Physiol Lung Cell Mol Physiol.
301:L519–L526. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Thurlbeck WM, Galaugher W and Mathers J:
Adaptive response to pneumonectomy in puppies. Thorax. 36:424–427.
1981. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Yao H, Chung S, Hwang JW, et al: SIRT1
protects against emphysema via FOXO3-mediated reduction of
premature senescence in mice. J Clin Invest. 122:2032–2045. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Podowski M, Calvi C, Metzger S, et al:
Angiotensin receptor blockade attenuates cigarette smoke-induced
lung injury and rescues lung architecture in mice. J Clin Invest.
122:229–240. 2012. View
Article : Google Scholar :
|
|
34
|
Houghton AM, Quintero PA, Perkins DL, et
al: Elastin fragments drive disease progression in a murine model
of emphysema. J Clin Invest. 116:753–759. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Takizawa H, Tanaka M, Takami K, et al:
Increased expression of transforming growth factor-beta1 in small
airway epithelium from tobacco smokers and patients with chronic
obstructive pulmonary disease (COPD). Am J Respir Crit Care Med.
163:1476–1483. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Churg A, Tai H, Coulthard T, Wang R and
Wright JL: Cigarette smoke drives small airway remodeling by
induction of growth factors in the airway wall. Am J Respir Crit
Care Med. 174:1327–1334. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Philipp K, Riedel F, Germann G, Hörmann K
and Sauerbier M: TGF-beta antisense oligonucleotides reduce mRNA
expression of matrix metalloproteinases in cultured
wound-healing-related cells. Int J Mol Med. 15:299–303.
2005.PubMed/NCBI
|
|
38
|
Königshoff M, Kneidinger N and Eickelberg
O: TGF-beta signaling in COPD: deciphering genetic and cellular
susceptibilities for future therapeutic regimen. Swiss Med Wkly.
139:554–563. 2009.PubMed/NCBI
|
