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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2015 Volume 11 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Role of microRNAs in skeletal muscle development and rhabdomyosarcoma (Review)

Huiming Ju, Yuefei Yang, Anzhi Sheng, Xing Jiang
Pages: 4019-4024
Published online on: 29 January 2015

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Review

Long non‑coding RNAs: Novel links in respiratory diseases (Review)

Yanru Liu, Ruifeng Zhang, Kejing Ying
Pages: 4025-4031
Published online on: 30 January 2015

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Article Open Access

Identification of the differentially expressed genes associated with familial combined hyperlipidemia using bioinformatics analysis

Xiaoli Luo, Changqing Yu, Chunjiang Fu, Weibin Shi, Xukai  Wang, Chunyu Zeng, Hongyong Wang
Pages: 4032-4038
Published online on: 27 January 2015

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Article Open Access

Expression of circulating microRNA-1 and microRNA-133 in pediatric patients with tachycardia

Ling Sun, Shuo Sun, Shaoying Zeng, Yufen Li, Wei Pan, Zhiwei Zhang
Pages: 4039-4046
Published online on: 23 January 2015

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Article Open Access

Naotaifang extract treatment results in increased ferroportin expression in the hippocampus of rats subjected to cerebral ischemia Corrigendum in /10.3892/mmr.2015.4630

Jun Liao, Xing Xia, Guo‑Zuo Wang, Yong‑Mei Shi, Jin‑Wen Ge
Pages: 4047-4052
Published online on: 06 February 2015

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Article Open Access

Cyclic adenosine monophosphate response element-binding protein transcriptionally regulates CHCHD2 associated with the molecular pathogenesis of hepatocellular carcinoma

Rui Song, Biao Yang, Xuesong Gao, Jinqian Zhang, Lei Sun, Peng  Wang, Yixing Meng, Qi Wang, Shunai Liu, Jun Cheng
Pages: 4053-4062
Published online on: 26 January 2015

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Article Open Access

Exendin-4 enhances the migration of adipose-derived stem cells to neonatal rat ventricular cardiomyocyte-derived conditioned medium via the phosphoinositide 3-kinase/Akt-stromal cell-derived factor-1α/CXC chemokine receptor 4 pathway

Hao Zhou, Junjie Yang, Ting Xin, Tao Zhang, Shunyin Hu, Shanshan Zhou, Guanghui Chen, Yundai Chen
Pages: 4063-4072
Published online on: 22 January 2015

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Article Open Access

Identification of genes and transcription factors associated with glucocorticoid response in lens epithelial cells

Ding Zhou, Yi Zhang, Lishan Wang, Yunduan Sun, Ping Liu
Pages: 4073-4078
Published online on: 06 February 2015

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Article Open Access

Association between oxidative DNA damage and the expression of 8-oxoguanine DNA glycosylase 1 in lung epithelial cells of neonatal rats exposed to hyperoxia

Linlin Jin, Haiping Yang, Jianhua Fu, Xindong Xue, Li Yao, Lin Qiao
Pages: 4079-4086
Published online on: 12 February 2015

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Article Open Access

Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin

Cheng Liu
Pages: 4087-4092
Published online on: 28 January 2015

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Article Open Access

Proteins S100A8 and S100A9 are potential biomarkers for renal cell carcinoma in the early stages: Results from a proteomic study integrated with bioinformatics analysis

Limin Zhang, Haowen Jiang, Gang Xu, Hui Wen, Bin Gu, Jun Liu, Shanghua Mao, Rong Na, Yan Jing, Qiang Ding, Yuanfang Zhang
Pages: 4093-4100
Published online on: 09 February 2015

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Article Open Access

Knockdown of yes-associated protein inhibits proliferation and downregulates large tumor suppressor 1 expression in MHCC97H human hepatocellular carcinoma cells

Cheng Wang, Zi‑Man Zhu, Cheng‑Li Liu, Xiao‑Jun He, Hong‑Yi Zhang, Jia‑Hong Dong
Pages: 4101-4108
Published online on: 26 January 2015

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Article Open Access

Early metabolic changes following ischemia onset in rats: An in vivo diffusion-weighted imaging and 1H-magnetic resonance spectroscopy study at 7.0 T

Gen Yan, Zhuozhi Dai, Yinghua Xuan, Renhua Wu
Pages: 4109-4114
Published online on: 30 January 2015

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Article Open Access

MicroRNA-145 suppresses cell proliferation, invasion and migration in pancreatic cancer cells by targeting NEDD9

Tong Han, Xiao‑Ping Yi, Bo Liu, Mu‑Jing Ke, Yi‑Xiong Li
Pages: 4115-4120
Published online on: 03 February 2015

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Article Open Access

A long-acting β2-adrenergic agonist increases the expression of muscarine cholinergic subtype‑3 receptors by activating the β2-adrenoceptor cyclic adenosine monophosphate signaling pathway in airway smooth muscle cells

Yuan‑Hua Liu, Song‑Ze Wu, Gang Wang, Ni‑Wen Huang, Chun‑Tao Liu
Pages: 4121-4128
Published online on: 05 February 2015

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Article Open Access

Oxymatrine inhibits the proliferation of prostate cancer cells in vitro and in vivo

Cunzao Wu, Weiping Huang, Yong Guo, Peng Xia, Xianbin Sun, Xiaodong Pan, Weilie Hu
Pages: 4129-4134
Published online on: 12 February 2015

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Article Open Access

Protective effect of Flt3L on organ structure during advanced multiorgan dysfunction syndrome in mice

Guang Tian, Jiangyang Lu, Huiqin Guo, Qian Liu, Hongwei Wang
Pages: 4135-4141
Published online on: 10 February 2015

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Article Open Access

Inhibitory activity of apogossypol in human prostate cancer in vitro and in vivo Corrigendum in /10.3892/mmr.2018.8571

Wenhua Zhan, Xingbin Hu, Jing Yi, Qunxing An, Xiaofeng Huang
Pages: 4142-4148
Published online on: 10 February 2015

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Article Open Access

PUFA diets alter the microRNA expression profiles in an inflammation rat model

Zheng Zheng, Yinlin Ge, Jinyu Zhang, Meilan Xue, Quan Li, Dongliang Lin, Wenhui Ma
Pages: 4149-4157
Published online on: 09 February 2015

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Article Open Access

Matrine inhibits the migratory and invasive properties of nasopharyngeal carcinoma cells

Bin Sun, Min Xu
Pages: 4158-4164
Published online on: 29 January 2015

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Article Open Access

p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis

Wang Miao, Xiaodong Liu, Hongqin Wang, Yimin Fan, Shizhong Lian, Xin Yang, Xinxing Wang, Geng Guo, Qichao Li, Sifei Wang
Pages: 4165-4173
Published online on: 26 January 2015

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Article Open Access

Acoustic radiation force impulse elastography, FibroScan®, Forns' index and their combination in the assessment of liver fibrosis in patients with chronic hepatitis B, and the impact of inflammatory activity and steatosis on these diagnostic methods

Dao‑Ran Dong, Mei‑Na Hao, Cheng Li, Ze Peng, Xia Liu, Gui‑Ping Wang, An‑Lin Ma
Pages: 4174-4182
Published online on: 04 February 2015

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Article Open Access

Role of the complement anaphylatoxin C5a-receptor pathway in atopic dermatitis in mice

Lin Dang, Lei He, Yan Wang, Jikui Xiong, Bingxue Bai, Yuzhen Li
Pages: 4183-4189
Published online on: 04 February 2015

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Article Open Access

Tanshinone ⅡA attenuates bleomycin-induced pulmonary fibrosis in rats

Huanyu He, Haiying Tang, Lili Gao, Yun Wu, Zhiqiang Feng, Hongli Lin, Taihua Wu
Pages: 4190-4196
Published online on: 11 February 2015

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Article Open Access

Screening and functional pathway analysis of genes associated with pediatric allergic asthma using a DNA microarray

Li‑Qun Lu, Wei Liao
Pages: 4197-4203
Published online on: 29 January 2015

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Article Open Access

Circadian gene hClock enhances proliferation and inhibits apoptosis of human colorectal carcinoma cells in vitro and in vivo

Yaping Wang, Ruizhe Qian, Ning Sun, Chao Lu, Zongyou Chen, Luchun Hua
Pages: 4204-4210
Published online on: 26 January 2015

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Article Open Access

Poly (ADP‑ribose) polymerase‑ and cytochrome c‑mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia‑induced hepatic failure

Guanmin Gao, Zujiang Yu, Jingya Yan, Jingjing Li, Shen Shen, Bin Jia, Kelei Guan, Xiaojuan Gao, Quancheng Kan
Pages: 4211-4219
Published online on: 29 January 2015

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Article Open Access

Correlation between microRNA‑21 and sprouty homolog 2 gene expression in multiple myeloma

Jin‑Hang Wang, Wen‑Wen Zheng, Shi‑Tong Cheng, Bo‑Xin Liu, Fu‑Rong Liu, Jian‑Qing Song
Pages: 4220-4224
Published online on: 29 January 2015

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Article Open Access

Zinc ion implantation‑deposition technique improves the osteoblast biocompatibility of titanium surfaces

Yongqiang Liang, Juan Xu, Jing Chen, Mengchun Qi, Xuehong Xie, Min Hu
Pages: 4225-4231
Published online on: 06 February 2015

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Article Open Access

2D-1H proton magnetic resonance spectroscopic imaging study on brain metabolite alterations in patients with diabetic hypertension

Zhen Cao, Bi‑Di Ye, Zhi-Wei Shen, Xiao‑Fang Cheng, Zhong‑Xian Yang, Yan‑Yan Liu, Ren‑Hua Wu, Kuan Geng, Ye‑Yu Xiao
Pages: 4232-4238
Published online on: 05 February 2015

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Article Open Access

Analysis of mechanical ventilation and lipopolysaccharide‑induced acute lung injury using DNA microarray analysis

Yuqing Chen, Xin Zhou, Ling Rong
Pages: 4239-4245
Published online on: 11 February 2015

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Article Open Access

Inflammation and pathological damage to the lungs of mice are only partially reversed following smoking cessation on subacute exposure to cigarette smoke

Hengyi Yan, Li Zhao, Xiaojie Wu, Hongbo Liu, Cen Wu, Yu Li, Wei Zheng, Hongfang Jiang
Pages: 4246-4254
Published online on: 11 February 2015

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Article

Chloroform fraction of Euphorbia maculata has antiplatelet activity via suppressing thromboxane B2 formation

Se‑Uk Kwon, Ji‑Yoon Cha, Hoon‑Yeon Lee, Mingjie Xin, Su‑Jeong Ji, Dae‑Ki Kim, Do‑Sim Park, Mi‑Kyung Pyo, Young‑Mi Lee
Pages: 4255-4261
Published online on: 09 February 2015

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Article

Inhibition of monocyte chemoattractant peptide-1 decreases secondary spinal cord injury

Xuesong Zhang, Chao Chen, Shengzhong Ma, Yan Wang, Xuelian Zhang, Xiaojing Su
Pages: 4262-4266
Published online on: 11 February 2015

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Article

Yes-associated protein regulates the growth of human non-small cell lung cancer in response to matrix stiffness

Yonggang Yuan, Weiliang Zhong, Ge Ma, Baoxiang Zhang, Hui Tian
Pages: 4267-4272
Published online on: 20 January 2015

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Article

Sclareol, a plant diterpene, exhibits potent antiproliferative effects via the induction of apoptosis and mitochondrial membrane potential loss in osteosarcoma cancer cells

Lin Wang, Hong‑Sheng He, Hua‑Long Yu, Yun Zeng, Heng Han, Ning He, Zhi‑Gang Liu, Zhi‑Yong Wang, Shou‑Jia Xu, Min Xiong
Pages: 4273-4278
Published online on: 10 February 2015

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Article

Endocrine gland‑derived vascular endothelial growth factor modulates proliferation, apoptosis and migration in pancreatic cancer cells

Linan Ren, Xiaozhong Guo, Xiaodong Shao, Hongyu Li, Hui Yao
Pages: 4279-4284
Published online on: 12 February 2015

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Article

Quercetin attenuates the effects of H2O2 on endoplasmic reticulum morphology and tyrosinase export from the endoplasmic reticulum in melanocytes

Cuiping Guan, Wen Xu, Weisong Hong, Miaoni Zhou, Fuquan Lin, Lifang Fu, Dongyin Liu, Aie Xu
Pages: 4285-4290
Published online on: 22 January 2015

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Article

Overexpression of p28GANK accelerates the metastasis of oesophageal squamous cell carcinoma

Shanhong Tang, Jianping Qin, Weihui Liu, Xiushan Zheng, Xiaoling Wu, Hui Xu, Lijuan Qiao, Quanshui Fan, Weizheng Zeng, Mingde Jiang
Pages: 4291-4296
Published online on: 30 January 2015

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Article

Side population cells and drug resistance in breast cancer

Meijian Wang, Yaqi Wang, Jun Zhong
Pages: 4297-4302
Published online on: 30 January 2015

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Article

Focal adhesion kinase regulates the phosphorylation protein tyrosine phosphatase-α at Tyr789 in breast cancer cells

Xu‑Qian Fang, Xiang‑Fan Liu, Ling Yao, Chang‑Qiang Chen, Jia‑Fei  Lin, Zhi‑Dong Gu, Pei‑Hua Ni, Xin‑Min Zheng, Qi‑Shi Fan
Pages: 4303-4308
Published online on: 27 January 2015

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Article

Tumor formation and drug resistance properties of human glioblastoma side population cells

Dong Chen
Pages: 4309-4314
Published online on: 29 January 2015

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Article

High GOLPH3 expression is associated with poor prognosis and invasion of hepatocellular carcinoma

Qian Li, Yuwen Ma, Wanpeng Xu
Pages: 4315-4320
Published online on: 28 January 2015

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Article

Advanced glycation end‑products affect the cytoskeletal structure of rat glomerular endothelial cells via the Ras‑related C3 botulinum toxin substrate 1 signaling pathway

Lei Lan, Yongsheng Han, Wei Ren, Jielong Jiang, Peng Wang, Zhao Hu
Pages: 4321-4326
Published online on: 06 February 2015

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Article

Icariin protects H9c2 cardiomyocytes from lipopolysaccharide‑induced injury via inhibition of the reactive oxygen species‑dependent c‑Jun N‑terminal kinases/nuclear factor-κB pathway

Heng Zhou, Yuan Yuan, Yuan Liu, Jian Ni, Wei Deng, Zhou-Yan Bian, Jia Dai, Qi-Zhu Tang
Pages: 4327-4332
Published online on: 30 January 2015

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Article

Antitumor effect and mechanism of action of a tumor-targeting recombinant human tumor necrosis factor-α fusion protein mediated by urokinase

You‑Chao Dai, Si‑Min Yang, Xin Wang, Yong‑Jun Zhou, Gan Hou, Di‑Nan Huang
Pages: 4333-4340
Published online on: 06 February 2015

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Article

Effect of oxidized low-density lipoprotein on the expression of the prorenin receptor in human aortic smooth muscle cells

Yunpeng Cheng, Xiaoyun Liu, Lijiao Zhang, Ying Zhang, Ying Liu, Yan Lu, Yinong Jiang
Pages: 4341-4344
Published online on: 26 January 2015

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Article

Elevated gene expression of S100A12 is correlated with the predominant clinical inflammatory factors in patients with bacterial pneumonia

Fei Hou, Likui Wang, Hong Wang, Junchao Gu, Meiling Li, Jingkai  Zhang, Xiao Ling, Xiaofang Gao, Cheng Luo
Pages: 4345-4352
Published online on: 04 February 2015

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Article

Inhibition of microRNA-25 by tumor necrosis factor α is critical in the modulation of vascular smooth muscle cell proliferation

Lichun Qi, Jixin Zhi, Tong Zhang, Xue Cao, Lixiu Sun, Yuanyuan Xu, Xueqi Li
Pages: 4353-4358
Published online on: 11 February 2015

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Article

A correlation study of telomere length in peripheral blood leukocytes and kidney function with age

Wei‑Guang Zhang, Yong Wang, Kai Hou, Lin-Pei Jia, Jie Ma, De-Long Zhao, Shu‑Ying  Zhu, Xiao‑Juan Bai, Guang‑Yan  Cai, Yan-Ping Wang, Xue‑Feng Sun, Xiang‑Mei Chen
Pages: 4359-4364
Published online on: 02 February 2015

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Article

Association of hsa-miR‑145 overexpression in human testicular cells with male infertility

Liyuan Zhang, Xianping Ding, Shuangshuang Nie, Jesse Li‑Ling, Yuping Zhang, Hui Zhang, Lin Chen, Lingxiao Li, Min Ding
Pages: 4365-4372
Published online on: 29 January 2015

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Article

β-adrenergic stimulation activates protein kinase Cε and induces extracellular signal-regulated kinase phosphorylation and cardiomyocyte hypertrophy

Lin Li, Hongyan Cai, Hua Liu, Tao Guo
Pages: 4373-4380
Published online on: 06 February 2015

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Article

Linear polyethylenimine-plasmid DNA nanoparticles are ototoxic to the cultured sensory epithelium of neonatal mice

Han Zhou, Xiaofeng Ma, Yongze Liu, Lei Dong, Yi Luo, Guangjie Zhu, Xiaoyun Qian, Jie Chen, Lin Lu, Junguo Wang, Xia Gao
Pages: 4381-4388
Published online on: 05 February 2015

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Article

A disintegrin and metallproteinase 15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis Retraction in /10.3892/mmr.2024.13165

Jinliang Gao, Wei Zheng, Liming Wang, Bailin Song
Pages: 4389-4396
Published online on: 04 February 2015

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Article

Effects of A2BR on the biological behavior of mouse renal fibroblasts during hypoxia

Jin Tang, Xianzhen Jiang, Yihong Zhou, Yingbo Dai
Pages: 4397-4402
Published online on: 09 February 2015

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Article

Atorvastatin induces autophagic cell death in prostate cancer cells in vitro

Zhenhua He, Jingmin Yuan, Ping Qi, Lixiu Zhang, Zhiping Wang
Pages: 4403-4408
Published online on: 11 February 2015

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Article

Effects of ethanol on the expression of caveolin-1 in HepG2 cells

Ying Wang, Jing Tong, Bing Chang, Bai‑Fang Wang, Dai Zhang, Bing‑Yuan Wang
Pages: 4409-4413
Published online on: 04 February 2015

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Article

Von Hippel-Lindau gene expression on the human fallopian tube epithelium during the menstrual cycle

Yan-Yan Lu, Wei-Jie Zhu, Bao-Guo Xie
Pages: 4414-4418
Published online on: 22 January 2015

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Article

Neuronic autophagy contributes to p-connexin 43 degradation in hippocampal astrocytes following traumatic brain injury in rats

Li Qian Sun, Jun Ling Gao, Ying Cui, Man Man Zhao, Xiao Bin Jing, Ran Li, Yan Xia Tian, Jian Zhong Cui, Zhong-Xue Wu
Pages: 4419-4423
Published online on: 27 January 2015

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Article

Apoptosis of Bel-7402 human hepatoma cells induced by a ruthenium(II) complex coordinated by cordycepin through the p53 pathway

Qun Lu, Wenjie Mei, Shaohong Luo, Weibin He
Pages: 4424-4430
Published online on: 04 February 2015

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Article

Bile acid promotes liver regeneration via farnesoid X receptor signaling pathways in rats

Long Ding, Yu Yang, Yikun Qu, Ting Yang, Kaifeng Wang, Weixin Liu, Weibin Xia
Pages: 4431-4437
Published online on: 29 January 2015

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Article

Electroacupuncture pretreatment induces tolerance against cerebral ischemia/reperfusion injury through inhibition of the autophagy pathway

Zhouquan Wu, Zhiqing Zou, Rong Zou, Xianju Zhou, Suyang Cui
Pages: 4438-4446
Published online on: 26 January 2015

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Article

Advanced glycation end products induce glomerular endothelial cell hyperpermeability by upregulating matrix metalloproteinase activity

Pengli Luo, Hui Peng, Canming Li, Zengchun Ye, Hua  Tang, Ying Tang, Cailian Chen, Tanqi Lou
Pages: 4447-4453
Published online on: 29 January 2015

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Lipopolysaccharide induces inflammation and facilitates lung metastasis in a breast cancer model via the prostaglandin E2-EP2 pathway

Shancheng Li, Xiaoya Xu, Man Jiang, Yuli Bi, Jiying Xu, Mingyong Han
Pages: 4454-4462
Published online on: 26 January 2015

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Association between the ABCC11 gene polymorphism and the expression of apolipoprotein D by the apocrine glands in axillary osmidrosis

Zhechen Zhu, Hongwei Zhang, Guanghua Luo, Ning Xu, Zhonglan Pan
Pages: 4463-4467
Published online on: 29 January 2015

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Article

Radix Dipsaci total saponins stimulate MC3T3-E1 cell differentiation via the bone morphogenetic protein-2/MAPK/Smad-dependent Runx2 pathway

Yin‑Bo Niu, Xiang‑He Kong, Yu‑Hua Li, Li Fan, Ya‑Lei Pan, Chen‑Rui Li, Xiang‑Long Wu, Ting‑Li Lu, Qi‑Bing Mei
Pages: 4468-4472
Published online on: 26 January 2015

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Heat shock protein 70 protects rat peritoneal mesothelial cells from advanced glycation end-products-induced epithelial-to-mesenchymal transition through mitogen‑activated protein kinases/extracellular signal-regulated kinases and transforming growth factor-β/Smad pathways

Jun Yang, Tiechui Zhu, Xiangdong Liu, Lianyun Zhang, Yuxin Yang, Jie Zhang, Minghao Guο
Pages: 4473-4481
Published online on: 29 January 2015

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Article

Suppression subtractive hybridization reveals differentially expressed genes in supraspinous ligaments of patients with ankylosing spondylitis

Ying Zhang, Xu Hu, Chao Zhang, Yue Zhou, Tong‑Wei Chu
Pages: 4482-4488
Published online on: 29 January 2015

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Article

Shp2 regulates chlorogenic acid-induced proliferation and adipogenic differentiation of bone marrow-derived mesenchymal stem cells in adipogenesis

Rong‑Ping Zhou, Ming‑Tao Deng, Lan‑Ying Chen, Ning Fang, Chuan Du, Lin‑Pan Chen, Ye‑Qing Zou, Jiang‑Hua Dai, Mei‑Lan Zhu, Wei Wang, Si‑Jian Lin, Rong‑Hua Liu, Jun Luo
Pages: 4489-4495
Published online on: 30 January 2015

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Article

Gene mutations in the D-loop region of mitochondrial DNA in oral squamous cell carcinoma

Rong‑Tao Yuan, Yang Sun, Ling‑Xue Bu, Mu‑Yun Jia
Pages: 4496-4500
Published online on: 22 January 2015

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Article

Activin A regulates proliferation, invasion and migration in osteosarcoma cells

Jianwei Zhu, Fan Liu, Quanming Wu, Xiancheng Liu
Pages: 4501-4507
Published online on: 30 January 2015

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Article

Prognostic significance of in situ and plasma levels of transforming growth factor β1, -2 and -3 in cutaneous melanoma

Ming‑Rui Tang, Yu‑Xin Wang, Shu Guo, Si‑Yuan Han, He‑Huan Li, Shi‑Feng Jin
Pages: 4508-4512
Published online on: 26 January 2015

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Article

Downregulation of high mobility group box 1 attenuates the severity of acute lung injury in endotoxemic mice

Xiaojuan Zhang, Zhenggang Luan, Yingjian Liang, Yina Liu, Xiaochun Ma
Pages: 4513-4517
Published online on: 26 January 2015

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Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion injury via Akt/endothelial nitric oxide synthase signaling and the B‑cell lymphoma/B‑cell lymphoma‑associated X protein pathway

Yiping Wang, Zhaohui Hu, Bing Sun, Jiahong Xu, Jinfa Jiang, Ming Luo
Pages: 4518-4524
Published online on: 11 February 2015

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Article

Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and promotes apoptosis of esophageal squamous cell lines

Junfen Ma, Xiaobing Guo, Shijie Zhang, Hongchun Liu, Jing Lu, Ziming Dong, Kangdong Liu, Liang Ming
Pages: 4525-4531
Published online on: 28 January 2015

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Article

Polyamines modulate the roscovitine-induced cell death switch decision autophagy vs. apoptosis in MCF-7 and MDA-MB-231 breast cancer cells

Elif Damla Arisan, Yunus Akkoç, Kaan Gencer Akyüz, Ezgi Melek Kerman, Pinar Obakan, Ajda Çoker‑Gürkan, Narçin Palavan Ünsal
Pages: 4532-4540
Published online on: 04 February 2015

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Article

MicroRNA-181 targets Yin Yang 1 expression and inhibits cervical cancer progression

Wen‑Yu Zhou, Jin‑Chan Chen, Ting‑Ting Jiao, Ning Hui, Xuan Qi
Pages: 4541-4546
Published online on: 10 February 2015

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Article

Cetuximab-induced insulin-like growth factor receptor I activation mediates cetuximab resistance in gastric cancer cells

Xin Li, Ling Xu, Heming Li, Lei Zhao, Ying Luo, Zhitu Zhu, Yunpeng Liu, Xiujuan Qu
Pages: 4547-4554
Published online on: 23 January 2015

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Article

Hypoxia-induced microRNA-155 promotes fibrosis in proximal tubule cells

Shenping Xie, Huaizhou Chen, Fei Li, Shu Wang, Junjun Guo
Pages: 4555-4560
Published online on: 10 February 2015

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Article

Cisplatin in combination with programmed cell death protein 5 increases antitumor activity in prostate cancer cells by promoting apoptosis

Wenbin Zhu, Yang Li, Lei Gao
Pages: 4561-4566
Published online on: 26 January 2015

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Article

MicroRNA-204 targets signal transducer and activator of transcription 5 expression and inhibits proliferation of B-cell lymphoma cells

Li Wu, Yong Li, Jian‑Min Fan, Zhi‑Min Zhang, Jin‑Ling Ouyang, Ting‑Ting Ni, Hai‑Xia Wu, Hang Li
Pages: 4567-4572
Published online on: 04 February 2015

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Article

α-tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells

Huarong Huang, Shaohua Chen, Jeremiah Van Doren, Dongli  Li, Chelsea Farichon, Yan  He, Qiuyan Zhang, Kun Zhang, Allan  H. Conney, Susan Goodin, Zhiyun Du, Xi Zheng
Pages: 4573-4578
Published online on: 22 January 2015

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Article

Polymorphism in the NLRP3 inflammasome-associated EIF2AK2 gene and inflammatory bowel disease

Geena Paramel Varghese, Ludmila Uporova, Jonas Halfvarson, Allan Sirsjö, Karin Fransén
Pages: 4579-4584
Published online on: 21 January 2015

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Article

Fibroblast activation protein and its prognostic significance in correlation with vascular endothelial growth factor in pancreatic adenocarcinoma

Dimitrios Patsouras, Kostis Papaxoinis, Alkiviadis Kostakis, Michael C. Safioleas, Andreas C. Lazaris, Polyxeni Nicolopoulou‑Stamati
Pages: 4585-4590
Published online on: 27 January 2015

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Article

MutL homolog 1 contributes to temozolomide-induced autophagy via ataxia-telangiectasia mutated in glioma

Yuhui Zou, Qiong Wang, Weimin Wang
Pages: 4591-4596
Published online on: 03 February 2015

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Article

Dibenzoylmethane, hydroxydibenzoylmethane and hydroxymethyldibenzoylmethane inhibit phorbol-12-myristate 13-acetate‑induced breast carcinoma cell invasion

Ya‑Fan Liao, Yew‑Min Tzeng, Hui‑Chih Hung, Guang‑Yaw Liu
Pages: 4597-4604
Published online on: 04 February 2015

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Article

Involvement of Fanconi anemia genes FANCD2 and FANCF in the molecular basis of drug resistance in leukemia

Chenjiao Yao, Wei Du, Haibiug Chen, Sheng Xiao, Lihua Huang, Fang-Ping Chen
Pages: 4605-4610
Published online on: 30 January 2015

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Article

Safflower polysaccharide inhibits the proliferation and metastasis of MCF-7 breast cancer cell

Zhongbing Luo, Hongxie Zeng, Yongqiang Ye, Lianbin Liu, Shaojin Li, Junyi Zhang, Rongcheng Luo
Pages: 4611-4616
Published online on: 06 February 2015

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Article

Oleuropein induces apoptosis via activation of caspases and suppression of phosphatidylinositol 3-kinase/protein kinase B pathway in HepG2 human hepatoma cell line

Chun‑Mei Yan, Er‑Qing Chai, Hong‑Yi Cai, Guo‑Ying Miao, Wen Ma
Pages: 4617-4624
Published online on: 28 January 2015

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Article

MicroRNA-185 downregulates androgen receptor expression in the LNCaP prostate carcinoma cell line

Chunyan Liu, Zhaobo Chen, Xiaoyan Hu, Lina Wang, Chaoyang Li, Jing Xue, Pengju Zhang, Weiwen Chen, Anli Jiang
Pages: 4625-4632
Published online on: 11 February 2015

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Article

Stromal cell-derived factor-1 G801A polymorphism and the risk factors for cervical cancer

Andrzej Roszak, Matthew Misztal, Anna Sowińska, Paweł P. Jagodziński
Pages: 4633-4638
Published online on: 06 February 2015

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Article

Increased oxidative stress and disrupted small intestinal tight junctions in cigarette smoke-exposed rats

Hongwei Li, Qi Wu, Long Xu, Xue Li, Jianmin Duan, Jingyan Zhan, Jing Feng, Xin Sun, Huaiyong Chen
Pages: 4639-4644
Published online on: 21 January 2015

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Article

microRNA‑299‑3p inhibits laryngeal cancer cell growth by targeting human telomerase reverse transcriptase mRNA

Man Li, Shi‑Ming Chen, Chen Chen, Zi‑Xiong Zhang, Meng‑Yuan Dai, Lei‑Bo Zhang, Shui‑Bin Wang, Qiong Dai, Ze‑Zhang Tao
Pages: 4645-4649
Published online on: 30 January 2015

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Article

Effects of hyperbaric oxygen therapy on NACHT domain-leucine-rich-repeat- and pyrin domain-containing protein 3 inflammasome expression in rats following spinal cord injury

Fang Liang, Chunsheng Li, Chunjin Gao, Zhuo Li, Jing  Yang, Xuehua Liu, Yong Wang
Pages: 4650-4656
Published online on: 06 February 2015

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Article

Intercellular transfer of messenger RNAs in multiorgan tumorigenesis by tumor cell-derived exosomes

Hong Jiang, Zheng Li, Xiaohua Li, Jianguo Xia
Pages: 4657-4663
Published online on: 06 February 2015

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Article

Single nucleotide polymorphisms in interleukin-6 and their association with venous thromboembolism

Umesh Yadav, Ailiman Mahemuti, Xuemei Hu, Kailibinure  Abudureheman, Yuning Xia, Baopeng Tang, Halmurat Upur
Pages: 4664-4670
Published online on: 26 January 2015

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Article

Hydroquinone analog 4-[(Tetrahydro-2H-pyran-2‑yl) oxy] phenol induces C26 colon cancer cell apoptosis and inhibits tumor growth in vivo

Qigen Du, Guang Xin, Hai Niu, Wen Huang
Pages: 4671-4677
Published online on: 04 February 2015

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Article

Curcumin inhibits autophagy and apoptosis in hypoxia/reoxygenation-induced myocytes

Zhouqing Huang, Bozhi Ye, Zhenyu Dai, Xinlei Wu, Zhongqiu Lu, Peiren Shan, Weijian Huang
Pages: 4678-4684
Published online on: 09 February 2015

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Article

Ovarian cancer stem-like cells elicit the polarization of M2 macrophages

Qing Zhang, Da‑Jun Cai, Bin Li
Pages: 4685-4693
Published online on: 09 February 2015

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Article

Indomethacin induces apoptosis in the EC109 esophageal cancer cell line by releasing second mitochondria-derived activator of caspase and activating caspase-3

Sida Qin, Chongwen Xu, Shuo Li, Chengcheng Yang, Xin  Sun, Xifang Wang, Shou‑Ching Tang, Hong Ren
Pages: 4694-4700
Published online on: 11 February 2015

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Article

MicroRNA-218 targets adiponectin receptor 2 to regulate adiponectin signaling

Hechun Du, Zimu Fu, Guohua He, Yuejuan Wang, Guiyu Xia, Min Fang, Tao Zhang
Pages: 4701-4705
Published online on: 30 January 2015

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Article

Dynamic correlation between induction of the expression of heme oxygenase-1 and hepatitis B viral replication

Yu‑Ming Shen, Hong‑Li Zhang, Yi‑Hang Wu, Xiao‑Ping Yu, Hua‑Jun Hu, Ling‑Hao Dai
Pages: 4706-4712
Published online on: 29 January 2015

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Article

3'-Azidothymidine may potently inhibit the biosynthesis of polylactosamine chains on highly glycosylated-CD147 and reduce matrix metalloproteinase-2 expression in SGC-7901 and U251 cells

Xu Xu, Yu Hu, Jianlong Ni, Shuijun Hu, Zhi Jiang, Lan Xu, Chunliang Liu, Dong Hua, Shiliang Wu
Pages: 4713-4719
Published online on: 22 January 2015

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Suppression of PKCε-mediated mitochondrial connexin 43 phosphorylation at serine 368 is involved in myocardial mitochondrial dysfunction in a rat model of dilated cardiomyopathy

Hu Shan, Jin Wei, Ming Zhang, Lin Lin, Rui Yan, Rong Zhang, Yan‑He Zhu
Pages: 4720-4726
Published online on: 27 January 2015

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Silencing of glutaminase 1 resensitizes Taxol-resistant breast cancer cells to Taxol

Aiqin Fu, Ze Yu, Yaobo Song, Enning Zhang
Pages: 4727-4773
Published online on: 27 January 2015

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August-2026 Volume 34 Issue 2

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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