|
1
|
Villa G and Hernández-Pastor LJ: Budget
impact analysis of first-line treatment with pazopanib for advanced
renal cell carcinoma in Spain. BMC Cancer. 13:3992013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Nguyen MM, Gill IS and Ellison LM: The
evolving presentation of renal carcinoma in the United States:
trends from the Surveillance, Epidemiology, and End Results
program. J Urol. 176:2397–2400; discussion. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Stafford HS, Saltzstein SL, Shimasaki S,
Sanders C, Downs TM and Sadler GR: Racial/ethnic and gender
disparities in renal cell carcinoma incidence and survival. J Urol.
179:1704–1708. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Schier AF: Nodal signaling in vertebrate
development. Annu Rev Cell Dev Biol. 19:589–621. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Quail DF, Siegers GM, Jewer M and Postovit
LM: Nodal signalling in embryogenesis and tumourigenesis. Int J
Biochem Cell Biol. 45:885–898. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tabibzadeh S and Hemmati-Brivanlou A:
Lefty at the crossroads of ‘stemness’ and differentiative events.
Stem Cells. 24:1998–2006. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Chen C and Shen MM: Two modes by which
Lefty proteins inhibit nodal signaling. Curr Biol. 14:618–624.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Strizzi L, Hardy KM, Kirsammer GT, Gerami
P and Hendrix MJ: Embryonic signaling in melanoma: potential for
diagnosis and therapy. Lab Invest. 91:819–824. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Strizzi L, Postovit LM, Margaryan NV, et
al: Nodal as a biomarker for melanoma progression and a new
therapeutic target for clinical intervention. Expert Rev Dermatol.
4:67–78. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Strizzi L, Hardy KM, Margaryan NV, et al:
Potential for the embryonic morphogen Nodal as a prognostic and
predictive biomarker in breast cancer. Breast Cancer Res.
14:R752012. View
Article : Google Scholar : PubMed/NCBI
|
|
11
|
McAllister JC, Zhan Q, Weishaupt C, Hsu MY
and Murphy GF: The embryonic morphogen, Nodal, is associated with
channel-like structures in human malignant melanoma xenografts. J
Cutan Pathol. 37(Suppl 1): 19–25. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Postovit LM, Margaryan NV, Seftor EA and
Hendrix MJ: Role of nodal signaling and the microenvironment
underlying melanoma plasticity. Pigment Cell Melanoma Res.
21:348–357. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hendrix MJ, Seftor EA, Seftor RE,
Kasemeier-Kulesa J, Kulesa PM and Postovit LM: Reprogramming
metastatic tumour cells with embryonic microenvironments. Nat Rev
Cancer. 7:246–255. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
14
|
Postovit LM, Margaryan NV, Seftor EA, et
al: Human embryonic stem cell microenvironment suppresses the
tumorigenic phenotype of aggressive cancer cells. Proc Natl Acad
Sci USA. 105:4329–4334. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Cucina A, Biava PM, D’Anselmi F, et al:
Zebrafish embryo proteins induce apoptosis in human colon cancer
cells (Caco2). Apoptosis. 11:1617–1628. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lee LM, Seftor EA, Bonde G, Cornell RA and
Hendrix MJ: The fate of human malignant melanoma cells transplanted
into zebrafish embryos: assessment of migration and cell division
in the absence of tumor formation. Dev Dyn. 233:1560–1570. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ebele JN, Sauter G, Epstein JI and
Sesterhenn IA: Pathology and Genetics of Tumours of the Urinary
System and Male Genital Organs. 1st. International Agency for
Research on Cancer Publications Collection; Lyon: 2004
|
|
18
|
Edge SB, Byrd DR, Compton CC, Fritz AG,
Greene FL and Trotti A: AJCC Cancer Staging Manual. 7th. Springer;
New York, NY: 2010
|
|
19
|
Nadeem L, Munir S, Fu G, et al: Nodal
signals through activin receptor-like kinase 7 to inhibit
trophoblast migration and invasion: implication in the pathogenesis
of preeclampsia. Am J Pathol. 178:1177–1189. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kobayashi T, Liu X, Wen FQ, et al: Smad3
mediates TGF-beta1-induced collagen gel contraction by human lung
fibroblasts. Biochem Biophys Res Commun. 339:290–295. 2006.
View Article : Google Scholar
|
|
21
|
Papageorgiou I, Nicholls PK, Wang F, et
al: Expression of nodal signalling components in cycling human
endometrium and in endometrial cancer. Reprod Biol Endocrinol.
7:1222009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lonardo E, Hermann PC, Mueller MT, et al:
Nodal/Activin signaling drives self-renewal and tumorigenicity of
pancreatic cancer stem cells and provides a target for combined
drug therapy. Cell Stem Cell. 9:433–446. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Lawrence MG, Margaryan NV, Loessner D, et
al: Reactivation of embryonic nodal signaling is associated with
tumor progression and promotes the growth of prostate cancer cells.
Prostate. 71:1198–1209. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Strizzi L, Postovit LM, Margaryan NV, et
al: Emerging roles of nodal and Cripto-1: from embryogenesis to
breast cancer progression. Breast Dis. 29:91–103. 2008.PubMed/NCBI
|
|
25
|
Cavallari C, Fonsato V, Herrera MB, Bruno
S, Tetta C and Camussi G: Role of Lefty in the anti tumor activity
of human adult liver stem cells. Oncogene. 32:819–826. 2013.
View Article : Google Scholar
|
|
26
|
Saito A, Ochiai H, Okada S, Miyata N and
Azuma T: Suppression of Lefty expression in induced pluripotent
cancer cells. FASEB J. 27:2165–2174. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Topczewska JM, Postovit LM, Margaryan NV,
et al: Embryonic and tumorigenic pathways converge via Nodal
signaling: role in melanoma aggressiveness. Nat Med. 12:925–932.
2006. View
Article : Google Scholar : PubMed/NCBI
|
|
28
|
Hardy KM, Kirschmann DA, Seftor EA, et al:
Regulation of the embryonic morphogen Nodal by Notch4 facilitates
manifestation of the aggressive melanoma phenotype. Cancer Res.
70:10340–10350. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Miyata N, Azuma T, Hozawa S, et al:
Transforming growth factor β and Ras/MEK/ERK signaling regulate the
expression level of a novel tumor suppressor Lefty. Pancreas.
41:745–752. 2012.PubMed/NCBI
|
|
30
|
De Silva T, Ye G, Liang YY, Fu G, Xu G and
Peng C: Nodal promotes glioblastoma cell growth. Front Endocrinol
(Lausanne). 3:592012.
|
