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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2015 Volume 12 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (Review)

Jue Jiang, Hong Jiang
Pages: 3-12
Published online on: 04 March 2015

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Review

Mycobacteriophages: An important tool for the diagnosis of Mycobacterium tuberculosis (Review)

Xiaoyan Fu, Mingxing Ding, Ning Zhang, Jicheng Li
Pages: 13-19
Published online on: 05 March 2015

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Article Open Access

Conditioned medium from umbilical cord mesenchymal stem cells induces migration and angiogenesis

Chongyang Shen, Puchang Lie, Tianyu Miao, Meixing Yu, Qiao Lu, Ting Feng, Jinrong Li, Tingting Zu, Xiaohuan Liu, Hong Li
Pages: 20-30
Published online on: 04 March 2015

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Article Open Access

Osteogenic cell fractions isolated from mouse tongue muscle

Koji Harada, Toyoko Harada, Tarannum Ferdous, Takanori Takenawa, Yoshiya Ueyama
Pages: 31-36
Published online on: 13 February 2015

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Article Open Access

N-acetylcysteine treatment following spinal cord trauma reduces neural tissue damage and improves locomotor function in mice

Jian Guo, Yiqiao Li, Zhong Chen, Zhennian He, Bin Zhang, Yonghuan Li, Jianghua Hu, Mingyuan Han, Yuanlin Xu, Yongfu Li
Pages: 37-44
Published online on: 26 February 2015

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Article Open Access

Klotho gene delivery ameliorates renal hypertrophy and fibrosis in streptozotocin-induced diabetic rats by suppressing the Rho-associated coiled-coil kinase signaling pathway

Minghong Deng, Yumei Luo, Yunkui Li, Qiuchen Yang, Xiaoqin Deng, Ping Wu, Houxun Ma
Pages: 45-54
Published online on: 17 February 2015

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Article Open Access

Screening for characteristic microRNAs between pre-invasive and invasive stages of cervical cancer

Xiao‑Lu Zhu, Shang‑Yun Wen, Zhi‑Hong Ai, Juan Wang, Yan‑Li Xu, Yin‑Cheng Teng
Pages: 55-62
Published online on: 17 February 2015

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Article Open Access

A disintegrin and metalloprotease 17 promotes microglial cell survival via epidermal growth factor receptor signalling following spinal cord injury Retraction in /10.3892/mmr.2024.13414

Zijian Wei, Deshui Yu, Yunlong Bi, Yang Cao
Pages: 63-70
Published online on: 27 February 2015

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Article Open Access

Afzelin attenuates asthma phenotypes by downregulation of GATA3 in a murine model of asthma

Wenbo Zhou, Xiuhong Nie
Pages: 71-76
Published online on: 26 February 2015

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Article Open Access

Expression of integrin-binding protein Nischarin in metastatic breast cancer

Jie Chen, Wei‑Liang Feng, Wen‑Ju Mo, Xiao‑Wen Ding, Shang‑Nao Xie
Pages: 77-82
Published online on: 18 February 2015

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Article Open Access

SOCS3 blocks HIF-1α expression to inhibit proliferation and angiogenesis of human small cell lung cancer by downregulating activation of Akt, but not STAT3

Jun Wan, Yun Che, Ningning Kang, Wei Wu
Pages: 83-92
Published online on: 17 February 2015

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Article Open Access

Overexpression of adenosine deaminase acting on RNA 1 in chordoma tissues is associated with chordoma pathogenesis by reducing miR‑125a and miR‑10a expression

Lei Kuang, Guohua Lv, Bing Wang, Lei Li, Yuliang Dai, Yawei Li
Pages: 93-98
Published online on: 12 February 2015

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Article Open Access

Ischemic postconditioning inhibits apoptosis in an in vitro proximal tubular cell model

Xiaodong Weng, Lei Wang, Hui Chen, Xiuheng Liu, Tao Qiu, Zhiyuan Chen
Pages: 99-104
Published online on: 12 February 2015

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Article Open Access

Circulating microRNA-196a as a candidate diagnostic biomarker for chronic hepatitis C

Bo Liu, Ying Xiang, Heng‑Shu Zhang
Pages: 105-110
Published online on: 24 February 2015

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Article Open Access

Cluster of differentiation 147 is a key molecule during hepatocellular carcinoma cell‑hepatic stellate cell cross‑talk in the rat liver

Tianyou Ma, Zhilun Wang, Zhantian Yang, Jinghong Chen
Pages: 111-118
Published online on: 04 March 2015

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Article Open Access

Estrogen receptor α mediates the effects of notoginsenoside R1 on endotoxin-induced inflammatory and apoptotic responses in H9c2 cardiomyocytes

Lei Zhong, Xing‑Lu Zhou, Yan‑Song Liu, Yi‑Min Wang, Fei Ma, Bao‑Liang Guo, Zhao‑Qi Yan, Qing‑Yuan Zhang
Pages: 119-126
Published online on: 27 February 2015

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Article Open Access

Thymosin β4 promotes hepatoblastoma metastasis via the induction of epithelial-mesenchymal transition

Xiaojun Fu, Peiyuan Cui, Fangfang Chen, Jianzhong Xu, Li  Gong, Lei Jiang, Dakun Zhang, Yongtao Xiao
Pages: 127-132
Published online on: 16 February 2015

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Article Open Access

Chitosan oligosaccharides in combination with Agaricus blazei Murill extract reduces hepatoma formation in mice with severe combined immunodeficiency

Ming‑Yang Yeh, Hung‑Sheng Shang, Hsu‑Feng Lu, Jason Chou, Chun Yeh, Jin‑Biou Chang, Hsiao‑Fang Hung, Wan‑Lin Kuo, Lung‑Yuan Wu, Jing‑Gung Chung
Pages: 133-140
Published online on: 09 March 2015

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Article Open Access

Correlation between the expression of DNMT1, and GSTP1 and APC, and the methylation status of GSTP1 and APC in association with their clinical significance in prostate cancer

Weijie Zhang, Hongliang Jiao, Xudong Zhang, Ruihua Zhao, Feng Wang, Wei He, Hong Zong, Qingxia Fan, Liuxing Wang
Pages: 141-146
Published online on: 03 March 2015

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Article Open Access

Fully human HER2/cluster of differentiation 3 bispecific antibody triggers potent and specific cytotoxicity of T lymphocytes against breast cancer

Yan Zhou, Lan‑Tu Gou, Zhi‑Hui Guo, Hai‑Rong Liu, Jiang‑Man Wang, Shu‑Xian Zhou, Jin‑Liang Yang, Xiao‑An Li
Pages: 147-154
Published online on: 05 March 2015

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Case Report Open Access

A patient with unusual features and a 69.5 Mb duplication from a de novo extra der (9): A case report

Yu‑Chun Zhou, Cui Zhang, Jin‑Sheng Zhai, Tian‑Fu Li, Qiu‑Yue Wu, Wei‑Wei Li, Na Li, Xiao‑Jun Li, Yu-Feng Huang, Ying‑Xia Cui, Xin‑Yi Xia
Pages: 155-158
Published online on: 05 March 2015

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Article Open Access

Protein identification from dried nipple aspirate fluid on Guthrie cards using mass spectrometry

Lucas Delmonico, Vivian Rabello Areias, Rodrigo César Pinto, Cintia Da Silva Matos, Marco Felipe Franco Rosa, Carolina Maria De Azevedo, Gilda Alves
Pages: 159-164
Published online on: 05 March 2015

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Article Open Access

All-trans retinoic acid impairs the vasculogenic mimicry formation ability of U87 stem-like cells through promoting differentiation

Geng‑Qiang Ling, Yi‑Jing Liu, Yi‑Quan Ke, Lei Chen, Xiao‑Dan Jiang, Chuan‑Lu Jiang, Wei Ye
Pages: 165-172
Published online on: 06 March 2015

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Article Open Access

In‑depth mapping of human testicular and epididymal proteins and their functional association with spermatozoa

Xuexia Liu, Fujun Liu
Pages: 173-179
Published online on: 05 March 2015

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Article Open Access

α-lipoic acid protects against hypoxia/reoxygenation-induced injury in human umbilical vein endothelial cells through suppression of apoptosis and autophagy

Jingjing Zhang, Houliang Deng, Li Liu, Xiaoxia Liu, Xialin Zuo, Qian Xu, Zhuomin Wu, Xiaobin Peng, Aimin Ji
Pages: 180-186
Published online on: 13 February 2015

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Article Open Access

Impact of tissue type and content of neoplastic cells of samples on the quality of epidermal growth factor receptor mutation analysis among patients with lung adenocarcinoma

Panagiotis Paliogiannis, Federico Attene, Antonio Cossu, Efisio Defraia, Giuseppe Porcu, Annamaria Carta, Maria Ignazia Sotgiu, Antonio Pazzola, Lorenzo Cordero, Francesca Capelli, Giovanni Maria Fadda, Salvatore Ortu, Giovanni Sotgiu, Grazia Palomba, Maria Cristina Sini, Giuseppe Palmieri, Maria Colombino
Pages: 187-191
Published online on: 12 February 2015

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Article Open Access

Chemoresistance to doxorubicin induces epithelial-mesenchymal transition via upregulation of transforming growth factor β signaling in HCT116 colon cancer cells

Jinpeng Li, Hao Liu, Jieping Yu, Honggang Yu
Pages: 192-198
Published online on: 16 February 2015

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Article Open Access

Immune‑enhancing effect of nano‑DNA vaccine encoding a gene of the prME protein of Japanese encephalitis virus and BALB/c mouse granulocyte‑macrophage colony‑stimulating factor

Yongzhen Zhai, Yan Zhou, Ximei Li, Guohe Feng
Pages: 199-209
Published online on: 04 March 2015

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Article Open Access

All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by downregulating p53 expression

Tao‑Gen Zhang, Xue‑Dong Li, Guo‑Yong Yu, Peng Xie, Yun‑Guo Wang, Zhao‑Yong Liu, Quan Hong, De‑Zhong Liu, Shi‑Xin Du
Pages: 210-218
Published online on: 04 March 2015

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Article Open Access

Monocyte chemotactic protein-1 promotes the proliferation and invasion of osteosarcoma cells and upregulates the expression of AKT

Quanchi Chen, Wei Sun, Yuxin Liao, Hui Zeng, Liancheng Shan, Fei Yin, Zhuoying Wang, Zifei Zhou, Yingqi Hua, Zhengdong Cai
Pages: 219-225
Published online on: 18 February 2015

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Article Open Access

Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin

Yong‑Bao Wei, Qiong Guo, Yun‑Liang Gao, Bin Yan, Zhao Wang, Jin‑Rui Yang, Wei Liu
Pages: 226-232
Published online on: 16 February 2015

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Article

Interleukin-4 affects the mature phenotype and function of rat bone marrow-derived dendritic cells

Shizhong Wang, Xiao Sun, Haijun Zhou, Zhichao Zhu, Wenjie Zhao, Chunfu Zhu
Pages: 233-237
Published online on: 13 February 2015

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Article

Dicaine represses apoptosis-linked gene 2-interacting protein X expression to induce airway epithelial barrier dysfunction

Jing‑Li Chen, Hong Yan
Pages: 238-242
Published online on: 05 March 2015

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Article

A subset of circulating microRNAs is expressed differently in patients with myocardial infarction

Jianqiu Liang, Shuchang Bai, Liang Su, Chen Li, Jiandi Wu, Zhangqing Xia, Dingli Xu
Pages: 243-247
Published online on: 04 March 2015

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Article

Estrogen receptorβ2 regulates interlukin-12 receptorβ2 expression via p38 mitogen-activated protein kinase signaling and inhibits non-small-cell lung cancer proliferation and invasion

Zhao‑Guo Liu, Xing‑Yuan Jiao, Zhen‑Guang Chen, Ke Feng, Hong‑He Luo
Pages: 248-254
Published online on: 17 February 2015

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Article

Arg972 insulin receptor substrate‑1 enhances tumor necrosis factor‑α‑induced apoptosis in osteoblasts

Yunhui You, Shiqing Liu, Lijuan Peng, Mei Long, Hongxiang Deng, Hongjun Zhao
Pages: 255-260
Published online on: 09 March 2015

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Article

Co‑culture with bone marrow stromal cells protects PC12 neuronal cells from tumor necrosis factor‑α‑induced apoptosis by inhibiting the tumor necrosis factor receptor/caspase signaling pathway

Li Li, Jing Wang, Ling Tang, Xin Yu, Yi Sui, Chaodong Zhang
Pages: 261-266
Published online on: 04 March 2015

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Article

Basic fibroblast growth factor lentiviral vector-transfected sheep bone marrow mesenchymal stem cells and non-specific osteogenic gene expression

Yang Hu, Qin Zhang, Lei Zhang, Xiao‑Xue Tang, Hui‑Yu He
Pages: 267-272
Published online on: 27 February 2015

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Article

Inhibitory effects of autologous γ-irradiated cell conditioned medium on osteoblasts in vitro

Xu‑Fang Li, Guo‑Ying Zhu, Jian‑Ping Wang, Yu Wang
Pages: 273-280
Published online on: 16 February 2015

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Article

Optimized codon usage enhances the expression and immunogenicity of DNA vaccine encoding Taenia solium oncosphere TSOL18 gene

Yuan‑Yuan Wang, Xue‑Lian Chang, Zhi‑Yong Tao, Xiao‑Li Wang, Yu‑Meng Jiao, Yong Chen, Wen‑Juan Qi, Hui Xia, Xiao‑Di Yang, Xin Sun, Ji‑Long Shen, Qiang Fang
Pages: 281-288
Published online on: 24 February 2015

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Article

Ubiquitin‑modified hepatitis B virus core antigen effectively facilitates antigen presentation and enhances cytotoxic T lymphocyte activity via the cytoplasmic transduction peptide in vitro

Linlin Song, Meng Zhuo, Yuyan Tang, Xiaohua Chen, Yongsheng Yu, Zhenghao Tang, Guoqing Zang
Pages: 289-296
Published online on: 13 February 2015

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Article

Protective and reversal effects of conserved dopamine neurotrophic factor on PC12 cells following 6-hydroxydopamine administration

Jiaming Mei, Chaoshi Niu
Pages: 297-302
Published online on: 24 February 2015

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Article

Synergistic hepatotoxicity by cadmium and chlorpyrifos: Disordered hepatic lipid homeostasis

Wei He, Wenli Guo, Yi Qian, Shuping Zhang, Difeng Ren, Sijin Liu
Pages: 303-308
Published online on: 24 February 2015

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Article

Pirfenidone inhibits proliferation, arrests the cell cycle, and downregulates heat shock protein‑47 and collagen type I in rat hepatic stellate cells in vitro

Xian‑Hong Xiang, Tian‑Peng Jiang, Shuai Zhang, Jie Song, Xing Li, Jian‑Yong Yang, Shi Zhou
Pages: 309-314
Published online on: 03 March 2015

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Article

Protective mechanism of Korean Red Ginseng in cisplatin-induced ototoxicity through attenuation of nuclear factor-κB and caspase-1 activation

Su‑Jin Kim, Hyun Jeong Kwak, Dae‑Seung Kim, Hyun‑Myung Choi, Jung‑Eun Sim, Sung‑Hoon Kim, Jae‑Young Um, Seung‑Heon Hong
Pages: 315-322
Published online on: 27 February 2015

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Article

Plasma sphingolipids: Potential biomarkers for severe hepatic fibrosis in chronic hepatitis C

Jun‑Feng Li, Feng Qu, Su‑Jun Zheng, Feng Ren, Hui‑Li Wu, Mei Liu, Jin‑Yu Ren, Yu Chen, Zhong‑Ping Duan, Jin‑Lan Zhang
Pages: 323-330
Published online on: 17 February 2015

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Article

High-dose insulin inhibits gap junction intercellular communication in vascular smooth muscle cells

Ou Bian, Haishan Zhang, Qigang Guan, Yingxian Sun, Dingyin Zeng
Pages: 331-336
Published online on: 05 March 2015

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Article

Apogossypolone induces reactive oxygen species accumulation and controls cell cycle progression in Raji Burkkit's lymphoma cells

Zhe‑Yu Hu, Fei Xu, Rui Sun, Yan‑Feng Chen, Dong‑Sheng Zhang, Yu‑Hua Fan, Jian Sun
Pages: 337-344
Published online on: 03 March 2015

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Article

Estimation of the environmental effect of natural volatile organic compounds from Chamaecyparis obtusa and their effect on atopic dermatitis-like skin lesions in mice

Hyun Yang, Changhwan Ahn, In‑Gyu Choi, Won‑Sil Choi, Mi‑Jin Park, Sung‑Suk Lee, Don‑Ha Choi, Eui‑Bae Jeung
Pages: 345-350
Published online on: 05 March 2015

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Article

Bioinformatics analysis of abnormal DNA methylation in muscle samples from monozygotic twins discordant for type 2 diabetes

Fei Liu, Qianqian Sun, Lingxiao Wang, Shuangshuang Nie, Jun Li
Pages: 351-356
Published online on: 06 March 2015

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Article

αB-crystallin reduces ristocetin‑induced soluble CD40 ligand release in human platelets: Suppression of thromboxane A2 generation

Masanori Tsujimoto, Tomoaki Doi, Gen Kuroyanagi, Naohiro Yamamoto, Rie Matsushima‑Nishiwaki, Yuko Iida, Yukiko Enomoto, Hiroki Iida, Shinji Ogura, Takanobu Otsuka, Haruhiko Tokuda, Osamu Kozawa, Toru Iwama
Pages: 357-362
Published online on: 06 March 2015

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Article

Short hairpin RNA targeting AKT1 and PI3K/p85 suppresses the proliferation and self-renewal of lung cancer stem cells

Ai‑Gui Jiang, Hui‑Yu Lu, De‑Geng Zhang, Li‑Xin Zhang, Xiao‑Yan Gao
Pages: 363-370
Published online on: 26 February 2015

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Article

Effect of astragaloside IV against rat myocardial cell apoptosis induced by oxidative stress via mitochondrial ATP-sensitive potassium channels

Feng‑Ying Guan, Shi‑Jie Yang, Jinxiang Liu, Si‑Rui Yang
Pages: 371-376
Published online on: 27 February 2015

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Article

Lentivirus-mediated knockdown of rhomboid domain containing 1 inhibits colorectal cancer cell growth

Junyi Han, Junchao Bai, Yao Yang, Hua Yin, Wei Gao, Aiguo Lu, Fei Liu, Haiyan Ge, Zhongmin Liu, Jinyi Wang, Lan Zhong
Pages: 377-381
Published online on: 17 February 2015

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Article

Icariin recovers the osteogenic differentiation and bone formation of bone marrow stromal cells from a rat model of estrogen deficiency-induced osteoporosis

Zhiqiang Luo, Minglu Liu, Likun Sun, Feilong Rui
Pages: 382-388
Published online on: 17 February 2015

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Article

Activation of the unfolded protein response in aged human lenses

He‑Zhen Tang, Li‑Min Yang
Pages: 389-393
Published online on: 04 March 2015

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Article

Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cells

Ravi Prakash Sahu
Pages: 394-400
Published online on: 18 February 2015

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Article

Ribonucleotide reductase M2 subunit expression and prognostic value in nasopharyngeal carcinoma

Ping Han, Zhi-Rui Lin, Li-Hua Xu, Qian Zhong, Xiao-Fen Zhu, Fa-Ya Liang, Qian Cai, Xiao-Ming Huang, Mu-Sheng Zeng
Pages: 401-409
Published online on: 16 February 2015

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Article

Prenatal nicotine exposure induces gender-associated left ventricular-arterial uncoupling in adult offspring

Zhenhua Wang, Qiufang Ouyang, Ziyang Huang, Ling Lin, Er'mei Yu, Markus W. Ferrari
Pages: 410-418
Published online on: 17 February 2015

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Article

Identification of a mutation in the WISP3 gene in three unrelated families with progressive pseudorheumatoid dysplasia

Yafen Yu, Man Hu, Xuesha Xing, Fang Li, Ying Song, Yang Luo, Hongwei Ma
Pages: 419-425
Published online on: 04 March 2015

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Article

Metastasis‑associated in colon cancer‑1 is associated with poor prognosis in hepatocellular carcinoma, partly by promoting proliferation through enhanced glucose metabolism

Yaoqing Li, Zhongtang Lu, Zheyong Liang, Dong Ji, Pengfei Zhang, Qingguang Liu, Xin Zheng, Yingmin Yao
Pages: 426-434
Published online on: 04 March 2015

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Article

Synergistic combination of histone deacetylase inhibitor suberoylanilide hydroxamic acid and oncolytic adenovirus ZD55-TRAIL as a therapy against cervical cancer

Xiujun Han, Shibing Wang, Wenjing Zhou, Ying Li, Wen Lei, Weiguo Lv
Pages: 435-441
Published online on: 16 February 2015

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Article

Transforming growth factor-β inhibits IQ motif containing guanosine triphosphatase activating protein 1 expression in lung fibroblasts via the nuclear factor-κB signaling pathway

Chuanyue Zong, Xianlong Zhang, Ying Xie, Jiawen Cheng
Pages: 442-448
Published online on: 13 February 2015

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Article

Downregulation of the expression of B‑cell lymphoma‑extra large by RNA interference induces apoptosis and enhances the radiosensitivity of non‑small cell lung cancer cells

Changbin Yang, Wei Huang, Ling Yan, Yu Wang, Weili Wang, Dezhi Liu, Xiaojun Zuo
Pages: 449-455
Published online on: 12 February 2015

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Article

Synergistic effects of combined treatment with simvastatin and exemestane on MCF‑7 human breast cancer cells

Yuanyuan Shen, Yingying Du, Ying Zhang, Yueyin Pan
Pages: 456-462
Published online on: 03 March 2015

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Article

MicroRNA-21, induced by high glucose, modulates macrophage apoptosis via programmed cell death 4

Yuan‑Yuan Shang, Ning‑Ning Fang, Feng Wang, Hui Wang, Zhi‑Hao Wang, Meng‑Xiong Tang, Jie Peng, Yun Zhang, Wei Zhang, Ming Zhong
Pages: 463-469
Published online on: 27 February 2015

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Article

Attenuation of enoyl coenzyme A hydratase 1 expression in colorectal cancer cells using small interfering RNA inhibits cell proliferation and migration

Qing‑Mei Zhao, Fei Kuang, Han Wu, Yu-Hao Zhang
Pages: 470-474
Published online on: 04 March 2015

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Article

Overexpression of serine/threonine‑protein kinase-1 in pancreatic cancer tissue: Serine/threonine-protein kinase-1 knockdown increases the chemosensitivity of pancreatic cancer cells

Qingguang Wang, Dong Xu, Chao Han, Min Tu, Qing Du, Jingjing Zhang, Yi Zhu, Lijian Xu
Pages: 475-481
Published online on: 05 March 2015

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Article

Identification and function analysis of contrary genes in Dupuytren's contracture

Xianglu Ji, Feng Tian, Lijie Tian
Pages: 482-488
Published online on: 09 March 2015

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Article

Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness

Dapeng Wu, Hongjie Yu, Jielin Sun, Jun Qi, Qiang Liu, Ruipeng Li, Siqun Lily Zheng, Jianfeng Xu, Jian Kang
Pages: 489-497
Published online on: 04 March 2015

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Article

Inhibition of the JAK2/STAT3 signaling pathway exerts a therapeutic effect on osteosarcoma

Jun Yan, Qianliang Wang, Kang Zou, Li Wang, Eric B. Schwartz, James R. Fuchs, Zugen Zheng, Jianqiang Wu
Pages: 498-502
Published online on: 05 March 2015

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Article

Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling

Ping He, Shuheng Jiang, Mingze Ma, Yang Wang, Rongkun Li, Fang Fang, Guangang Tian, Zhigang Zhang
Pages: 503-509
Published online on: 04 March 2015

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Case Report

A novel endoglin mutation in hereditary hemorrhagic telangiectasia type 1: A case report

Yanjun Lu, Yaowu Zhu, Lili Shi, Hongtao Zhen, Ziyong Sun, Liming Cheng
Pages: 510-512
Published online on: 05 March 2015

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Article

Effects of RNA interference-mediated NRP-1 silencing on the proliferation and apoptosis of breast cancer cells

Zhengxiang Han, Guan Jiang, Yingying Zhang, Jie Xu, Chong Chen, Lansheng Zhang, Zhenyuan Xu, Xiuping Du
Pages: 513-519
Published online on: 03 March 2015

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Article

Metformin alleviates high glucose‑mediated oxidative stress in rat glomerular mesangial cells by modulation of p38 mitogen-activated protein kinase expression in vitro

Xin‑Ming Yao, Shan‑Dong Ye, Chun‑Chun Xiao, Jun‑Fei Gu, Di Yang, Shan Wang
Pages: 520-526
Published online on: 06 March 2015

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Article

Deregulated microRNA species in the plasma and placenta of patients with preeclampsia

Sheng Yang, Hailing Li, Qinyu Ge, Li Guo, Feng Chen
Pages: 527-534
Published online on: 04 March 2015

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Article

Inhibition of autophagy by 3-methyladenine potentiates sulforaphane-induced cell death of BE(2)-C human neuroblastoma cells

Irena Horwacik, Monika Gaik, Małgorzata Durbas, Elżbieta Boratyn, Grzegorz Zając, Katarzyna Szychowska, Małgorzata Szczodrak, Henryk Kołoczek, Hanna Rokita
Pages: 535-542
Published online on: 18 February 2015

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Article

Serum pentraxin 3 is a novel marker in Crohn's disease

Jingbo Chen, Xiaolin Xu, Lijian Xia, Xiangpeng Xi, Bo Liu, Mingyu Yang
Pages: 543-546
Published online on: 06 March 2015

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Article

Inhibition of livin expression suppresses cell proliferation and enhances chemosensitivity to cisplatin in human lung adenocarcinoma cells

Li Zhuang, Li‑Da Shen, Kun Li, Run‑Xiang Yang, Qin‑Yong Zhang, Yun Chen, Chun‑Lin Gao, Chao Dong, Qing Bi, Jing‑Nan Tao, Xiao‑Nan Wang, Qing Tian
Pages: 547-552
Published online on: 18 February 2015

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Article

B-cell lymphoma 2 and β-catenin expression in colorectal cancer and their prognostic role following surgery

Manuela Balzi, Maria Novella Ringressi, Paola Faraoni, Catherine Booth, Antonio Taddei, Luca Boni, Paolo Bechi
Pages: 553-560
Published online on: 24 February 2015

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Article

MicroRNA-125b is involved in atherosclerosis obliterans in vitro by targeting podocalyxin

Xiaobing Li, Na Yao, Juan Zhang, Zhenjiang Liu
Pages: 561-568
Published online on: 24 February 2015

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Article

Inhibitory effect of receptor for advanced glycation end product‑specific small interfering RNAs on the development of hepatic fibrosis in primary rat hepatic stellate cells

Jin‑Rong Xia, Ting‑Ting Chen, Wei‑Dong Li, Feng‑Lin Lu, Juan Liu, Xiao‑Gang Cai, Qin Lu, Cui-Ping Yang
Pages: 569-574
Published online on: 12 February 2015

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Article

FoxO6 inhibits cell proliferation in lung carcinoma through up-regulation of USP7

Hong-Jun Hu, Li-Guo Zhang, Zhen-Hua Wang, Xi-Xi Guo
Pages: 575-580
Published online on: 17 February 2015

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Article

Ku70 is essential for histone deacetylase inhibitor trichostatin A-induced apoptosis

Jin Meng, Feng Zhang, Xu‑Tao Zhang, Tao Zhang, Yu‑Hua Li, Lei Fan, Yang Sun, He‑Long Zhang, Qi‑Bing Mei
Pages: 581-586
Published online on: 16 February 2015

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Article

Nodal activates smad and extracellular signal-regulated kinases 1/2 pathways promoting renal cell carcinoma proliferation

Zhiwei Zhang, Tao Jiang, Quanlin Li, Jianbo Wang, Deyong Yang, Xiancheng Li, Qifei Wang, Xishuang Song
Pages: 587-594
Published online on: 12 February 2015

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Article

Interleukin-1β induced nuclear factor-κB binds to a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 9 promoter in human chondrosarcoma cells

Aynur Altuntas, Sevil Oskay Halacli, Ozlem Cakmak, Gonul Erden, Sumeyya Akyol, Veli Ugurcu, Satoshi Hirohata, Kadir Demircan
Pages: 595-600
Published online on: 06 March 2015

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Article

Simultaneous silencing of XIAP and survivin causes partial mesenchymal-epithelial transition of human pancreatic cancer cells via the PTEN/PI3K/Akt pathway

Xiao‑Ping Yi, Tong Han, Yi‑Xiong Li, Xue‑Ying Long, Wen‑Zheng Li
Pages: 601-608
Published online on: 20 February 2015

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Article

Ginsenoside Rg3 sensitizes human non‑small cell lung cancer cells to γ-radiation by targeting the nuclear factor-κB pathway

Lei Wang, Xiankui Li, Yi‑Min Song, Bin Wang, Fu‑Rui Zhang, Rui Yang, Hua‑Qi Wang, Guo‑Jun Zhang
Pages: 609-614
Published online on: 27 February 2015

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Article

Identification and validation of reference genes for the detection of serum microRNAs by reverse transcription‑quantitative polymerase chain reaction in patients with bladder cancer

Lishui Wang, Yimin Liu, Lutao Du, Juan Li, Xiumei Jiang, Guixi Zheng, Ailin Qu, Haiyan Wang, Lili Wang, Xin Zhang, Hui Liu, Hongwei Pan, Yongmei Yang, Chuanxin Wang
Pages: 615-622
Published online on: 04 March 2015

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Article

Molecular mechanism underlying the anticancer effect of simvastatin on MDA‑MB‑231 human breast cancer cells

Yuan‑Yuan Shen, Yuan Yuan, Ying‑Ying Du, Yue‑Yin Pan
Pages: 623-630
Published online on: 04 March 2015

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Article

Recombinant receptor activator of nuclear factor κB exhibits more marked inhibitory effects on osteoclasts compared with recombinant osteoprotegerin in vitro and in vivo

Qi Xiong, Lingli Xin, Licheng Zhang, Peifu Tang, Lihai Zhang
Pages: 631-638
Published online on: 03 March 2015

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Article

Activation of notch signaling mediates the induction and maintenance of mechanical allodynia in a rat model of neuropathic pain

Keliang Xie, Yingping Jia, Ying Hu, Yanyan Sun, Lichao Hou, Guolin Wang
Pages: 639-644
Published online on: 20 February 2015

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Article

A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p and miR-182-5p on insulin-like growth factor II, insulin-like growth factor-1 receptor and insulin-like growth factor-binding protein-3 in hepatocellular carcinoma

Reem Amr Assal, Hend Mohamed El Tayebi, Karim Adel Hosny, Gamal Esmat, Ahmed Ihab Abdelaziz
Pages: 645-650
Published online on: 24 February 2015

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Article

Angiotensin II promotes melanogenesis via angiotensin II type 1 receptors in human melanocytes

Li‑Hong Liu, Xin Fan, Hai‑Tao Li, Xu‑Xi An, Rong‑Ya Yang
Pages: 651-656
Published online on: 05 March 2015

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Article

Orostachys japonicus inhibits the expression of MMP-2 and MMP-9 mRNA and modulates the expression of iNOS and COX-2 genes in human PMA-differentiated THP-1 cells via inhibition of NF-κB and MAPK activation

Young Il Kim, Seung‑Won Park, Yeo‑Kwang Yoon, Kyung‑Wook Lee, Jang‑Hoon Lee, Hong‑Jung Woo, Youngchul Kim
Pages: 657-662
Published online on: 10 March 2015

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Article

Synergistic effects of oxyresveratrol in conjunction with antibiotics against methicillin-resistant Staphylococcus aureus

Dae‑Ki Joung, Sung‑Hoon Choi, Ok‑Hwa Kang, Sung‑Bae Kim, Su‑Hyun Mun, Yun‑Soo Seo, Da-Hye Kang, Ryong Gong, Dong‑Won Shin, Youn-Chul Kim, Dong‑Yeul Kwon
Pages: 663-667
Published online on: 12 February 2015

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Article

MicroRNA-183/182/96 cooperatively regulates the proliferation of colon cancer cells

Qingquan Zhang, Wei Ren, Bin Huang, Liang Yi, Hongtao Zhu
Pages: 668-674
Published online on: 18 February 2015

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Article

Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism

Zhibin Xiao, Pengcheng Ren, Yang Chao, Qianyun Wang, Jianke Kuai, Miaomiao Lv, Lei Chen, Changjun Gao, Xude Sun
Pages: 675-683
Published online on: 04 March 2015

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Article

Beneficial effects of tripterygium glycosides tablet on biomarkers in patients with ankylosing spondylitis

Wei Ji, Yajun Chen, Xia Zhao, Yunke Guo, Lingyu Zhong, Honggang Li, Dan Wang, Yanna Song
Pages: 684-690
Published online on: 06 March 2015

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Article

Role of p53β in the inhibition of proliferation of gastric cancer cells expressing wild-type or mutated p53

Wansheng Ji, Jingrong Ma, Hongmei Zhang, Hua Zhong, Lei Li, Na Ding, Jianxin Jiao, Zhixing Gao
Pages: 691-695
Published online on: 18 February 2015

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Article

Testosterone enhances lipopolysaccharide-induced interleukin-6 and macrophage chemotactic protein-1 expression by activating the extracellular signal-regulated kinase 1/2/nuclear factor-κB signalling pathways in 3T3-L1 adipocytes

Chunlin Su, Min Chen, Haiyan Huang, Jinfang Lin
Pages: 696-704
Published online on: 03 March 2015

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Article

Ligustrazine attenuates the platelet‑derived growth factor-BB-induced proliferation and migration of vascular smooth muscle cells by interrupting extracellular signal-regulated kinase and P38 mitogen-activated protein kinase pathways

Lifei Yu, Xiaojing Huang, Kai Huang, Chun Gui, Qiaojuan Huang, Bin Wei
Pages: 705-711
Published online on: 24 February 2015

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Article

Antioxidant activity is required for the protective effects of cyclophilin A against oxidative stress

Kiyoon Kim, In Kyung Oh, Kyung Sik Yoon, Joohun Ha, Insug Kang, Wonchae Choe
Pages: 712-718
Published online on: 26 February 2015

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Article

Combination of cytokinin and auxin induces apoptosis, cell cycle progression arrest and blockage of the Akt pathway in HeLa cells

Liwei Zhao, Peng Liu, Guangqin Guo, Li Wang
Pages: 719-727
Published online on: 04 March 2015

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Article

Regulation of the expression of claudin 23 by the enhancer of zeste 2 polycomb group protein in colorectal cancer

Natalia Maryan, Malgorzata Statkiewicz, Michal Mikula, Krzysztof Goryca, Agnieszka Paziewska, Adriana Strzałkowska, Michalina Dabrowska, Mateusz Bujko, Jerzy Ostrowski
Pages: 728-736
Published online on: 19 February 2015

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Article

Immunohistochemical profile of cytokines and growth factors expressed in vestibular schwannoma and in normal vestibular nerve tissue

Samanta Taurone, Enrica Bianchi, Giuseppe Attanasio, Cira Di Gioia, Rocco Ierinó, Cecilia Carubbi, Daniela Galli, Francesco Saverio Pastore, Felice Giangaspero, Roberto Filipo, Christian Zanza, Marco Artico
Pages: 737-745
Published online on: 04 March 2015

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Article

Use of the disulfiram/copper complex for breast cancer chemoprevention in MMTV‑erbB2 transgenic mice

Yanhui Yang, Qian Deng, Xiaoshan Feng, Junjun Sun
Pages: 746-752
Published online on: 04 March 2015

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Article

Downregulation of matrix metalloproteinase 9 by small interfering RNA inhibits the tumor growth of ovarian epithelial carcinoma in vitro and in vivo Retraction in /10.3892/mmr.2021.12391

Fengjun Guo, Jingyan Tian, Manhua Cui, Meiru Fang, Lin Yang
Pages: 753-759
Published online on: 04 March 2015

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Article

Vasoactive intestinal peptide induces CD14+HLA-DR‑/low myeloid-derived suppressor cells in gastric cancer

Gang Li, Ke Wu, Kaixiong Tao, Xiaoming Lu, Jianhua Ma, Zhengqiang Mao, Hang Li, Liang Shi, Jing Li, Yanfeng Niu, Fan Xiang, Guobin Wang
Pages: 760-768
Published online on: 18 February 2015

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Article

Antiproliferative effects of anastrozole on MCF‑7 human breast cancer cells in vitro are significantly enhanced by combined treatment with testosterone undecanoate

Rong Chen, Junwei Cui, Qinqin Wang, Peng Li, Xiaoling Liu, Hui Hu, Wei Wei
Pages: 769-775
Published online on: 04 March 2015

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Review Open Access

Lipid metabolism disorders and bone dysfunction - interrelated and mutually regulated (Review)

Li Tian, Xijie Yu
Pages: 783-794
Published online on: 11 March 2015

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Review

Positive and negative regulators of the metallothionein gene (Review)

Shinichiro Takahashi
Pages: 795-799
Published online on: 09 March 2015

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Article Open Access

Identification of biomarkers regulated by rexinoids (LGD1069, LG100268 and Ro25-7386) in human breast cells using Affymetrix microarray

Hye‑Sook Seo, Jong‑Kyu Woo, Yong Cheol Shin, Seong‑Gyu Ko
Pages: 800-818
Published online on: 12 March 2015

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Differentiation of human umbilical cord mesenchymal stem cells into germ-like cells in mouse seminiferous tubules

Hui Chen, Qiu‑Ling Tang, Xiao‑Ying Wu, Li‑Chun Xie, Li‑Min Lin, Gu‑Yu Ho, Lian Ma
Pages: 819-828
Published online on: 23 March 2015

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Effects of pinacidil on changes to the microenvironment around the incision site, of a skin/muscle incision and retraction, in a rat model of postoperative pain

Su Cao, Yinbin Qin, Junjie Chen, Shiren Shen
Pages: 829-836
Published online on: 10 March 2015

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Effects of silencing the ATP-binding cassette protein E1 gene by electroporation on the proliferation and migration of EC109 human esophageal cancer cells

Xiao-Rui Li, Liu-Zhong Yang, Xiao-Qing Huo, Ying Wang, Qing-Hui Yang, Qing-Qin Zhang
Pages: 837-842
Published online on: 19 March 2015

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High glucose promotes gastric cancer chemoresistance in vivo and in vitro

Wei Zhao, Rui Chen, Mei Zhao, Liang Li, Lin Fan, Xiang‑Ming Che
Pages: 843-850
Published online on: 20 March 2015

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Transforming growth factor‑β, insulin‑like growth factor I/insulin‑like growth factor I receptor and vascular endothelial growth factor‑A: Prognostic and predictive markers in triple‑negative and non‑triple‑negative breast cancer

Abeer Bahhnassy, Marwa Mohanad, Sabry Shaarawy, Manal F. Ismail, Ahmed El‑Bastawisy, Abeer M. Ashmawy, Abdel‑Rahman Zekri
Pages: 851-864
Published online on: 27 March 2015

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Trop2 inhibition suppresses the proliferation and invasion of laryngeal carcinoma cells via the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway

Xu‑Dong Wang, Qiang Wang, Xiao‑Lin Chen, Jian‑Fei Huang, Yong Yin, Peng Da, Hao Wu
Pages: 865-870
Published online on: 13 March 2015

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Case Report Open Access

Spindle cell oncocytoma of the adenohypophysis: Two case reports and a review of the literature

Qingchun Mu, Jinlu Yu, Limei Qu, Xitong Hu, Haijun Gao, Pengfei Liu, Xu Zheng, Yuxue Sun, Haiyan Huang
Pages: 871-876
Published online on: 12 March 2015

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Gliotoxin potentiates osteoblast differentiation by inhibiting nuclear factor-κB signaling

Guangye Wang, Xiaohai Zhang, Baoqing Yu, Ke Ren
Pages: 877-884
Published online on: 20 March 2015

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Integrated microRNA-mRNA analysis revealing the potential roles of microRNAs in tongue squamous cell cancer

Xiao‑Li Zhou, Jun‑Hua Wu, Xin‑Juan Wang, Fu‑Jun Guo
Pages: 885-894
Published online on: 11 March 2015

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Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin

Xia Kong, Sheng‑Hua Wu, Li Zhang, Xiao‑Qing Chen
Pages: 895-904
Published online on: 05 March 2015

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Overexpression of caudal type homeobox transcription factor 2 inhibits the growth of the MGC‑803 human gastric cancer cell line in vivo

Weiyuan Wei, Lei Li, Xiaotong Wang, Linhai Yan, Wenlong Cao, Zexu Zhan, Xiaoshi Zhang, Han Yu, Yubo Xie, Qiang Xiao
Pages: 905-912
Published online on: 04 March 2015

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Efficient labeling in vitro with non-ionic gadolinium magnetic resonance imaging contrast agent and fluorescent transfection agent in bone marrow stromal cells of neonatal rats

Ying‑Qin Li, Ying Tang, Rao Fu, Qiu‑Hua Meng, Xue Zhou, Ze‑Min Ling, Xiao Cheng, Su‑Wei Tian, Guo‑Jie Wang, Xue‑Guo Liu, Li‑Hua Zhou
Pages: 913-920
Published online on: 23 March 2015

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Implication of microRNA regulation in para-phenylenediamine-induced cell death and senescence in normal human hair dermal papilla cells

Ok‑Kyu Lee, Hwa Jun Cha, Myung Joo Lee, Kyung Mi Lim, Jae Wook Jung, Kyu Joong Ahn, In‑Sook An, Sungkwan An, Seunghee Bae
Pages: 921-936
Published online on: 13 March 2015

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Resveratrol analog piceatannol restores the palmitic acid‑induced impairment of insulin signaling and production of endothelial nitric oxide via activation of anti‑inflammatory and antioxidative heme oxygenase‑1 in human endothelial cells

Sun‑Oh Jeong, Yong Son, Ju Hwan Lee, Yong‑Kwan Cheong, Seong Hoon Park, Hun‑Taeg Chung, Hyun‑Ock Pae
Pages: 937-944
Published online on: 26 March 2015

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An integrated analysis of the effects of microRNA and mRNA on esophageal squamous cell carcinoma

Yong Yang, Dianbo Li, Yang Yang, Gening Jiang
Pages: 945-952
Published online on: 27 March 2015

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Enterovirus 71 induces apoptosis of SH‑SY5Y human neuroblastoma cells through stimulation of endogenous microRNA let-7b expression

Xiling Du, Haipeng Wang, Fuhui Xu, Yongyi Huang, Zhixue Liu, Te Liu
Pages: 953-959
Published online on: 13 March 2015

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RNA silencing of integrin-linked kinase increases the sensitivity of the A549 lung cancer cell line to cisplatin and promotes its apoptosis

Xiaozhen Zhao, Zhenye Xu, Zhongqi Wang, Zhonghua Wu, Yabin Gong, Lijuan Zhou, Yi Xiang
Pages: 960-966
Published online on: 11 March 2015

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Expression signatures of long non-coding RNAs in early brain injury following experimental subarachnoid hemorrhage

Bingjie Zheng, Huailei Liu, Ruke Wang, Shancai Xu, Yaohua Liu, Kaikai  Wang, Xu Hou, Chen Shen, Jianing Wu, Xin Chen, Pei Wu, Guang Zhang, Zhiyong Ji, Hongyu Wang, Yao Xiao, Jianyi Han, Huaizhang Shi, Shiguang Zhao
Pages: 967-973
Published online on: 11 March 2015

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Association of neonatal necrotizing enterocolitis with myeloid differentiation-2 and GM2 activator protein genetic polymorphisms

Wei Zhou, Weiming Yuan, Longguang Huang, Ping Wang, Xiao Rong, Juan Tang
Pages: 974-980
Published online on: 17 March 2015

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Gene expression changes in human mesenchymal stem cells from patients with osteoporosis

Lianyong Liu, Qingyun Zhu, Jingnan Wang, Qian Xi, Hongling Zhu, Mingjun Gu
Pages: 981-987
Published online on: 19 March 2015

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Ameliorative effects of Gualou Guizhi decoction on inflammation in focal cerebral ischemic-reperfusion injury

Yuqin Zhang, Shengnan Zhang, Huang Li, Mei Huang, Wei Xu, Kedan Chu, Lidian Chen, Xianwen Chen
Pages: 988-994
Published online on: 19 March 2015

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Impact of Brachyury on epithelial-mesenchymal transitions and chemosensitivity in non-small cell lung cancer

Ke Xu, Bin Liu, Yongyu Liu
Pages: 995-1001
Published online on: 13 February 2015

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Somatostatin prevents lipopolysaccharide‑induced neurodegeneration in the rat substantia nigra by inhibiting the activation of microglia

Lijuan Bai, Xique Zhang, Xiaohong Li, Na Liu, Fan Lou, Honglei Ma, Xiaoguang Luo, Yan Ren
Pages: 1002-1008
Published online on: 13 March 2015

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Calcitriol ameliorates renal damage in a pre‑established proteinuria model

Edgar Maquigussa, Carine P. Arnoni, Luciana G. Pereira, Mirian A. Boim
Pages: 1009-1015
Published online on: 27 March 2015

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MicroRNA-218 and microRNA-520a inhibit cell proliferation by downregulating E2F2 in hepatocellular carcinoma

Ye Dong, Jianjun Zou, San Su, Huiyi Huang, Yanzhen Deng, Birong Wang, Weidong Li
Pages: 1016-1022
Published online on: 19 March 2015

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Apoptin-modified human mesenchymal stem cells inhibit growth of lung carcinoma in nude mice

Jingchun Du, Yanling Zhang, Chun Xu, Xia Xu
Pages: 1023-1029
Published online on: 17 March 2015

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cDNA microarray analysis of the effect of cantharidin on DNA damage, cell cycle and apoptosis-associated gene expression in NCI-H460 human lung cancer cells in vitro

Te‑Chun Hsia, Chien‑Chih Yu, Shu‑Chun Hsu, Nou‑Ying Tang, Hsu‑Feng Lu, Chun‑Shu Yu, Shin‑Hwar Wu, Jaung‑Geng Lin, Jing‑Gung Chung
Pages: 1030-1042
Published online on: 24 March 2015

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Salubrinal protects cardiomyocytes against apoptosis in a rat myocardial infarction model via suppressing the dephosphorylation of eukaryotic translation initiation factor 2α

Rui‑Jun Li, Kun‑Lun He, Xin Li, Li‑Li Wang, Chun‑Lei Liu, Yun‑Yun He
Pages: 1043-1049
Published online on: 18 March 2015

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Overexpression of N‑myc downstream‑regulated gene 1 inhibits human glioma proliferation and invasion via phosphoinositide 3‑kinase/AKT pathways

Wei Ma, Meng Na, Chongyang Tang, Haiyang Wang, Zhiguo Lin
Pages: 1050-1058
Published online on: 13 March 2015

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Epigenetic modification and preliminary investigation of the mechanism of the immune evasion of HL-60 cells

Jin Hong Liu, Yong Mei Bian, Yi Xie, Dao Pei Lu
Pages: 1059-1065
Published online on: 20 March 2015

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Effects of OsteoKing on osteoporotic rabbits

Lifen Dai, Haiying Wu, Shan Yu, Hongbin Zhao, Lanjie Xue, Ming Xu, Zhiqiang Shen, Min Hu
Pages: 1066-1074
Published online on: 26 March 2015

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Litsea japonica extract inhibits neuronal apoptosis and the accumulation of advanced glycation end products in the diabetic mouse retina

Junghyun Kim, Chan‑Sik Kim, Yun Mi Lee, Eunjin Sohn, Kyuhyung Jo, Jin Sook Kim
Pages: 1075-1081
Published online on: 24 March 2015

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Sevoflurane ameliorates intestinal ischemia-reperfusion-induced lung injury by inhibiting the synergistic action between mast cell activation and oxidative stress

Chenfang Luo, Dongdong Yuan, Weicheng Zhao, Huixin Chen, Gangjian Luo, Guangjie Su, Ziqing Hei
Pages: 1082-1090
Published online on: 23 March 2015

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Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat‑induced pulmonary fibrosis

Zhizhou Yang, Zhaorui Sun, Hongmei Liu, Yi Ren, Danbing Shao, Wei Zhang, Jinfeng Lin, Joy Wolfram, Feng Wang, Shinan Nie
Pages: 1091-1097
Published online on: 24 March 2015

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Agmatine protects Müller cells from high‑concentration glucose‑induced cell damage via N‑methyl‑D‑aspartic acid receptor inhibition

Ning Han, Li Yu, Zhidu Song, Lifu Luo, Yazhen Wu
Pages: 1098-1106
Published online on: 24 March 2015

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Article

Knockdown of ubiquitin protein ligase E3A affects proliferation and invasion, and induces apoptosis of breast cancer cells through regulation of annexin A2

Xiaofang Zhou, Shishan Deng, Hai Liu, Yang Liu, Zhengwei Yang, Tianyong Xing, Baoqian Jing, Xiaoming Zhang
Pages: 1107-1113
Published online on: 26 March 2015

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Article

Antineoplastic effect of a novel chemopreventive agent, neokestose, on the Caco-2 cell line via inhibition of expression of nuclear factor-κB and cyclooxygenase-2

Shun‑Mei Lee, Jan‑Yi Chang, Jiann‑Shing Wu, Dey‑Chyi Sheu
Pages: 1114-1118
Published online on: 18 March 2015

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Article

Ehlers-Danlos syndrome type IV is associated with a novel G984R COL3A1 mutation

Yao Deng, Shijie Wei, Shijun Hu, Jinlan Chen, Zhiping Tan, Yifeng Yang
Pages: 1119-1124
Published online on: 13 March 2015

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Article

Verifying the markers of ovarian cancer using RNA‑seq data

Tianfeng Liu, Nina Yu, Feng Ding, Surong Wang, Shihong Li, Xiaofei Zhang, Xiangxiu Sun, Ying Chen, Peishu Liu
Pages: 1125-1130
Published online on: 13 March 2015

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Article

Vaccarin promotes endothelial cell proliferation in association with neovascularization in vitro and in vivo

Fengshan Xie, Lei Feng, Weiwei Cai, Yuyu Qiu, Yanling  Liu, Yue Li, Bin Du, Liying Qiu
Pages: 1131-1136
Published online on: 18 March 2015

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Article

Generation of transgenic fibroblasts producing doxycycline‑inducible human interferon‑α or erythropoietin for a bovine mammary bioreactor

Hee Young Kang, Eui‑Ju Hong, Kyu‑Chan Hwang, Nam‑Hyung Kim, Woo‑Suk Hwang, Eui‑Bae Jeung
Pages: 1137-1144
Published online on: 13 March 2015

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Article

Acetyl‑l‑carnitine prevents homocysteine‑induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells

Shui‑Ping Yang, Xiu‑Zhen Yang, Guo‑Ping Cao
Pages: 1145-1150
Published online on: 13 March 2015

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Article

Curcumin triggers apoptosis via upregulation of Bax/Bcl-2 ratio and caspase activation in SW872 human adipocytes

Lin Zhu, Ming Bao Han, Yuan Gao, Huan Wang, Ling Dai, Ying Wen, Li Xin Na
Pages: 1151-1156
Published online on: 06 March 2015

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Article

Antibody microarray profiling of osteosarcoma cell serum for identifying potential biomarkers

Zi-Qiang Zhu, Jin-Shan Tang, Duan Gang, Ming-Xing Wang, Jian-Qiang Wang, Zhou Lei, Zhou Feng, Ming-Liang Fang, Lin Yan
Pages: 1157-1162
Published online on: 24 March 2015

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Article

MicroRNA‑423‑5p targets O‑GlcNAc transferase to induce apoptosis in cardiomyocytes

Peng Luo, Tao He, Rongjian Jiang, Gang Li
Pages: 1163-1168
Published online on: 13 March 2015

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Article

Ischemic postconditioning regulates cardiomyocyte autophagic activity following ischemia/reperfusion injury

Liang Guo, Jun‑Mei Xu, Xiao‑Ye Mo
Pages: 1169-1176
Published online on: 24 March 2015

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Article

Clinicopathological significance of cytoplasmic transducer of ErbB2. 1 expression in gastric cancer

Su‑Qing Zhang, Ke‑Kang Sun, Xiao‑Yang Wu, Ning Zhong, Hua Zhao, De‑Chun Li
Pages: 1177-1182
Published online on: 11 March 2015

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Article

Apoptosis induced by sonodynamic therapy in human osteosarcoma cells in vitro

Xing Liu, Wei Li, Shuo Geng, Qing‑Gang Meng, Zheng‑Gang Bi
Pages: 1183-1188
Published online on: 12 March 2015

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Article

Nitrogen permease regulator‑like 2 enhances sensitivity to oxaliplatin in colon cancer cells

Ming‑Na Liu, Ai‑Yun Liu, Ya‑Ju Du, Feng‑Hua Pei, Xin‑Hong Wang, Jing Chen, Dan Liu, Bing‑Rong Liu
Pages: 1189-1196
Published online on: 13 March 2015

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Article

RNAi-mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non-small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Pages: 1197-1204
Published online on: 12 March 2015

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Article

Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone

Myung Joo Lee, Hwa Jun Cha, Kyung Mi Lim, Ok‑Kyu Lee, Seunghee Bae, Chun‑Ho Kim, Kee‑Ho Lee, Yu Na Lee, Kyu Joong Ahn, Sungkwan An
Pages: 1205-1212
Published online on: 12 March 2015

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Article

Design, expression and characterization of single chain Fv, Mms13 and the single chain Fv‑mms13 fusion protein

Deng Kong, Xiaoke Wang, Xiaohong Wang, Xueyun Wang, Xiaoli Chen, Guoqiang Ji, Xinhua Fu, Shouxun Wang
Pages: 1213-1218
Published online on: 27 March 2015

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Article

Identification of KRAS and PIK3CA but not BRAF mutations in patients with gastric cancer

Weipeng Lu, Hong Wei, Mei Li, Hai Wang, Lina Liu, Qiuping Zhang, Lisha Liu, Shen Lu
Pages: 1219-1224
Published online on: 23 March 2015

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Article

Comparative analysis of the influence of Fructus Ligustri Lucidi on a rat lumbar disc herniation model

Ya‑Xin Han, Dong Liang, Xiao‑Rui Han, De‑Yong Liang
Pages: 1225-1232
Published online on: 24 March 2015

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Article

Arsenic trioxide inhibits breast cancer cell growth via microRNA‑328/hERG pathway in MCF‑7 cells

Ying Wang, Leqiu Wang, Changhao Yin, Baizhu An, Yankun Hao, Tao Wei, Li Li, Gaochen Song
Pages: 1233-1238
Published online on: 27 March 2015

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Article

Computational networks of activating transcription factor 3 gene in Huh7 cell lines and hepatitis C virus-infected Huh7 cell lines

Jingkun Liu, Bing Wang, Wenjun Wang, Mingzhu Sun, Yapping Li, Xiaoli Jia, Song Zhai, Shuangsuo Dang
Pages: 1239-1246
Published online on: 26 March 2015

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Article

3,3'-Diindolylmethane attenuates cardiac H9c2 cell hypertrophy through 5'-adenosine monophosphate-activated protein kinase-α

Jing Zong, Qing‑Qing Wu, Heng Zhou, Jie‑Yu Zhang, Yuan Yuan, Zhou‑Yan Bian, Wei Deng, Jia Dai, Fang‑Fang Li, Man Xu, Yi Fang, Qi‑Zhu Tang
Pages: 1247-1252
Published online on: 20 March 2015

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Article

Curcuma zedoaria (Berg.) Rosc. essential oil and paclitaxel synergistically enhance the apoptosis of SKOV3 cells

Yunxiao Zhou, Jie Shen, Liqun Xia, Yanli Wang
Pages: 1253-1257
Published online on: 11 March 2015

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Article

Upregulated microRNA-214 enhances cardiac injury by targeting ITCH during coxsackievirus infection

Zhi‑Gang Chen, Hui Liu, Jun‑Biao Zhang, Shao‑Li Zhang, Li‑Hua Zhao, Wan‑Qian Liang
Pages: 1258-1264
Published online on: 24 March 2015

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Article

Somatic mutations in myeloid cell leukemia‑1 contribute to the pathogenesis of glioma by prolonging its half‑life

Xiupeng Lv, Guang Tan, Yiqun Yao, Li Lv, Xiaoqin Deng, Lei Dong, Shuang Li, Linlin Li, Yinghui Xu
Pages: 1265-1271
Published online on: 13 March 2015

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Article

Blood-brain barrier permeability of Gualou Guizhi granules and neuroprotective effects in ischemia/reperfusion injury

Huang Li, Miao Ye, Yuqin Zhang, Mingqing Huang, Wei Xu, Kedan Chu, Lidian Chen, Jinhua Que
Pages: 1272-1278
Published online on: 20 March 2015

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Article

High-mobility group nucleosome-binding domain 2 protein inhibits the invasion of Klebsiella pneumoniae into mouse lungs in vivo

Shuang Zheng, Laibin Ren, Heng Li, Xiaofei Shen, Xiaolong Yang, Na Li, Xinyuan Wang, Xiaojuan Guo, Xiaoying Wang, Ning Huang
Pages: 1279-1285
Published online on: 10 March 2015

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Article

VP22 mediates intercellular trafficking and enhances the in vitro antitumor activity of PTEN

Xian Yu, Zhengmin Xu, Jun Lei, Tingting Li, Yan Wang
Pages: 1286-1290
Published online on: 18 March 2015

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Article

Anti-profibrotic effects of artesunate on bleomycin-induced pulmonary fibrosis in Sprague Dawley rats

Changming Wang, Xiuping Xuan, Wenmin Yao, Guojin Huang, Junfei Jin
Pages: 1291-1297
Published online on: 17 March 2015

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Article

Golgi phosphoprotein 3 expression predicts poor prognosis in patients with prostate cancer undergoing radical prostatectomy

Longyang Zhang, Feng Guo, Xinghua Gao, Yanlin Wu
Pages: 1298-1304
Published online on: 09 March 2015

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Article

Cbl participates in shikonin-induced apoptosis by negatively regulating phosphoinositide 3-kinase/protein kinase B signaling

Dan Qu, Xiao‑Man Xu, Meng Zhang, Ting‑Shu Jiang, Yi Zhang, Sheng‑Qi Li
Pages: 1305-1313
Published online on: 18 March 2015

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Article

Zanthoxylum schinifolium leaf ethanol extract inhibits adipocyte differentiation through inactivation of the extracellular signal regulated kinase and phosphoinositide 3-kinase/Akt signaling pathways in 3T3-L1 pre-adipocytes

Eun‑Ok Choi, Cheol Park, Soon Shik Shin, Eun‑Ju Cho, Byung Woo Kim, Jin Ah Hwang, Hye‑Jin Hwang, Yung Hyun Choi
Pages: 1314-1320
Published online on: 10 March 2015

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Article

Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains Corrigendum in /mmr/12/3/3998

Hai Xia Hu, Ru Hui Lin, Xiao Qin Zhu, Zuan Fang Li, Li Dian Chen
Pages: 1321-1327
Published online on: 19 March 2015

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Article

DNA-dependent protein kinase catalytic subunit inhibitor reverses acquired radioresistance in lung adenocarcinoma by suppressing DNA repair

Yong Li, Hang Li, Wen Peng, Xin‑Yun He, Min Huang, Dong Qiu, Ying‑Bo Xue, Liang Lu
Pages: 1328-1334
Published online on: 18 March 2015

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Article

Extracts of Scutellariae Radix inhibit low-density lipoprotein oxidation and the lipopolysaccharide-induced macrophage inflammatory response

Ohn Soon Kim, Chang‑Seob Seo, Yeji Kim, Hyeun‑Kyoo Shin, Hyekyung Ha
Pages: 1335-1341
Published online on: 17 March 2015

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Article

Carbamylated low-density lipoprotein attenuates glucose uptake via a nitric oxide-mediated pathway in rat L6 skeletal muscle cells

Hye‑Jung Choi, Kyoung Jae Lee, Eun Ah Hwang, Kyo‑Cheol Mun, Eunyoung Ha
Pages: 1342-1346
Published online on: 13 March 2015

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Article

Curcumin protects renal tubular epithelial cells from high glucose-induced epithelial-to-mesenchymal transition through Nrf2-mediated upregulation of heme oxygenase-1

Xiuli Zhang, Dan Liang, Lin Guo, Wei Liang, Yan Jiang, Hongjuan Li, Yue Zhao, Shumin Lu, Zhi‑Hong Chi
Pages: 1347-1355
Published online on: 27 March 2015

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Article

Fetuin-A 742 (C/T) and 766 (C/G) polymorphic sites are associated with increased risk of myocardial infarction in older patients (≥40 years of age)

Ajda Coker‑Gurkan, Deniz Coskun, Elif Damla Arisan, Pinar Obakan, Özer Soylu, Narcin Palavan Unsal
Pages: 1356-1362
Published online on: 20 March 2015

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Article

A novel molecular probe 131I-K237 targeting tumor angiogenesis in human prostate cancer xenografts

Qian Zhao, Yu Zhang, Jun Guo, Juan Li
Pages: 1363-1367
Published online on: 18 March 2015

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Article

Modulatory role of resveratrol on cytotoxic activity of cisplatin, sensitization and modification of cisplatin resistance in colorectal cancer cells

Abdel‑Moneim M. Osman, Hamdan S. Al‑Malki, Sameer E. Al‑Harthi, Amr A. El‑Hanafy, Hassan M. Elashmaoui, Mohamed F. Elshal
Pages: 1368-1374
Published online on: 19 March 2015

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Article

Regulation of the oncogenic function of distal-less 4 by microRNA-122 in hepatocellular carcinoma

Xu-Hua Xie, Xiao-Pei Xu, Chang-Yu Sun, Zu-Jiang Yu
Pages: 1375-1380
Published online on: 27 March 2015

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Article

CD9 modulates proliferation of human glioblastoma cells via epidermal growth factor receptor signaling

Gong‑Ping Wang, Xiao‑Fang Han
Pages: 1381-1386
Published online on: 10 March 2015

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Article

Angiotensin‑(1‑7) stimulates cholesterol efflux from angiotensin II‑treated cholesterol‑loaded THP‑1 macrophages through the suppression of p38 and c‑Jun N‑terminal kinase signaling

Hui‑Yu Yang, Yun‑Fei Bian, Chuan‑Shi Xiao, Bin Liang, Nana Zhang, Fen Gao, Zhi‑Ming Yang
Pages: 1387-1392
Published online on: 13 March 2015

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Article

Investigating polymorphisms in membrane-associated transporter protein SLC45A2, using sucrose transporters as a model

Anke Reinders, John M. Ward
Pages: 1393-1398
Published online on: 10 March 2015

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Article

Upregulated microRNA-16 as an oncogene in renal cell carcinoma

Duqun Chen, Yifan Li, Zuhu Yu, Zhengming Su, Wenshui Yu, Yuchi Li, Shangqi Yang, Yaoting Gui, Liangchao Ni, Yongqing Lai
Pages: 1399-1404
Published online on: 17 March 2015

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Article

Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma

Xiao Wu, Bao‑Jun Liu, Shumeng Ji, Jing‑Feng Wu, Chang‑Qing Xu, Yi‑Jie Du, Xiao‑Fang You, Bei Li, Jing‑Jing Le, Hai‑Lin Xu, Xiao‑Hong Duan, Jing‑Cheng Dong
Pages: 1405-1412
Published online on: 27 March 2015

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Article

Upregulation of microRNA‑492 induced by epigenetic drug treatment inhibits the malignant phenotype of clear cell renal cell carcinoma in vitro

Aibing Wu, Kunpeng Wu, Mingchun Li, Lingli Bao, Xiang Shen, Shunjun Li, Jinmei Li, Zhixiong Yang
Pages: 1413-1420
Published online on: 26 March 2015

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Article

Enoyl-coenzyme A hydratase short chain 1 silencing attenuates the proliferation of hepatocellular carcinoma by inhibiting epidermal growth factor signaling in vitro and in vivo

Bi-Yun Lin, Chuan-Xing Xiao, Wen-Xiu Zhao, Li Xiao, Xu Chen, Ping Li, Xiao-Min Wang
Pages: 1421-1428
Published online on: 09 March 2015

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Article

Apoptosis of HL-60 human leukemia cells induced by Asiatic acid through modulation of B-cell lymphoma 2 family proteins and the mitogen-activated protein kinase signaling pathway

Qiuling Wu, Tingting Lv, Yan Chen, Lu Wen, Junli Zhang, Xudong Jiang, Fang Liu
Pages: 1429-1434
Published online on: 24 March 2015

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Article

DNA methyltransferase 3, a target of microRNA-29c, contributes to neuronal proliferation by regulating the expression of brain-derived neurotrophic factor

Guoshuai Yang, Yanmin Song, Xiaoyan Zhou, Yidong Deng, Tao Liu, Guohu Weng, Dan Yu, Suyue Pan
Pages: 1435-1442
Published online on: 23 March 2015

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Article

Violacein induces p44/42 mitogen-activated protein kinase‑mediated solid tumor cell death and inhibits tumor cell migration

Toral Mehta, Koen Vercruysse, Terrance Johnson, Anthony Okechukwu Ejiofor, Elbert Myles, Quincy Antoine Quick
Pages: 1443-1448
Published online on: 20 March 2015

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Article

Synergistic effects of valproic acid and arsenic trioxide on RPMI8226 cells in vitro and the possible underlying mechanisms

Xiaoning Wang, Mei Zhang
Pages: 1449-1456
Published online on: 20 March 2015

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Article

Inhibition of Forkhead box protein M1 by thiostrepton increases chemosensitivity to doxorubicin in T-cell acute lymphoblastic leukemia

Jian‑Yong Wang, Xiu‑Hong Jia, Hai‑Yan Xing, You‑Jie Li, Wen‑Wen Fan, Na Li, Shu‑Yang Xie
Pages: 1457-1464
Published online on: 11 March 2015

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Article

Artesunate induces apoptosis and inhibits growth of Eca109 and Ec9706 human esophageal cancer cell lines in vitro and in vivo

Liang Liu, Lian‑Fu Zuo, Jing Zuo, Jing Wang
Pages: 1465-1472
Published online on: 20 March 2015

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Article

MicroRNA‑133a inhibits proliferation and invasion, and induces apoptosis in gastric carcinoma cells via targeting fascin actin‑bundling protein 1 Retraction in /10.3892/mmr.2021.12185

Chen Lai, Zihua Chen, Ruixin Li
Pages: 1473-1478
Published online on: 24 March 2015

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Article

Resveratrol suppresses vascular endothelial growth factor secretion via inhibition of CXC-chemokine receptor 4 expression in ARPE-19 cells

Hyemin Seong, Jinhyun Ryu, Joo Yeon Jeong, In Young Chung, Yong‑Seop Han, Soo Hyun Hwang, Jong Moon Park, Sang Soo Kang, Seong Wook Seo
Pages: 1479-1484
Published online on: 20 March 2015

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Article

Overexpression of Tyro3 receptor tyrosine kinase leads to the acquisition of taxol resistance in ovarian cancer cells

Chuhee Lee
Pages: 1485-1492
Published online on: 24 March 2015

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Article

Ophiopogonin‑D suppresses MDA‑MB‑435 cell adhesion and invasion by inhibiting matrix metalloproteinase‑9

Yuanyuan Zhang, Yuwei Han, Kefeng Zhai, Minhui Sun, Jihua Liu, Boyang Yu, Junping Kou
Pages: 1493-1498
Published online on: 24 March 2015

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Article

Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway

Zhiqiang Zhang, Yongchao Fang, Qiang Wang, Yu Sun, Chuanzhi Xiong, Li Cao, Beiyue Wang, Nirong Bao, Jianning Zhao
Pages: 1499-1505
Published online on: 23 March 2015

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Article

Paclitaxel resistance in MCF-7/PTX cells is reversed by paeonol through suppression of the SET/phosphatidylinositol 3-kinase/Akt pathway

Weipeng Zhang, Jiangxia Cai, Siying Chen, Xiaowei Zheng, Sasa Hu, Weihua Dong, Jun Lu, Jianfeng Xing, Yalin Dong
Pages: 1506-1514
Published online on: 11 March 2015

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Article

Emerging role of microRNA-27a in human malignant glioma cell survival via targeting of prohibitin

Wei Chen, Jun Qi, Gang Bao, Tuo Wang, Chang‑Wang Du, Mao‑De Wang
Pages: 1515-1523
Published online on: 12 March 2015

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Article

Identification of active ingredients in Wuzhuyu decoction improving migraine in mice by spectral efficiency association

Xueqiang Pan, Manyuan Wang, Yanchuan Wu, Xuran Lu, Yawen Shang, Yongsong Xu, Yongsong Zhai, Jing Li, Zhaoxia Li, Muxin Gong
Pages: 1524-1534
Published online on: 18 March 2015

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Article

MicroRNA-509-3p inhibits cancer cell proliferation and migration by targeting the mitogen-activated protein kinase kinase kinase 8 oncogene in renal cell carcinoma

Zhengming Su, Duqun Chen, Enpu Zhang, Yifan Li, Zuhu Yu, Min Shi, Zhimao Jiang, Liangchao Ni, Shangqi Yang, Yaoting Gui, Jiongxian Ye, Yongqing Lai
Pages: 1535-1543
Published online on: 17 March 2015

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Article

Effects of glucose-dependent insulinotropic polypeptide receptor knockout and a high-fat diet on cognitive function and hippocampal gene expression in mice Erratum in /10.3892/mmr.2015.4078

Rachael R. Lennox, Charlotte Moffett, David W. Porter, Nigel Irwin, Victor A. Gault, Peter R. Flatt
Pages: 1544-1548
Published online on: 06 March 2015

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Article

MicroRNA-146b-5p inhibits the growth of gallbladder carcinoma by targeting epidermal growth factor receptor

Jingli Cai, Lubai Xu, Zhenzhai Cai, Jisheng Wang, Bing Zhou, Hai Hu
Pages: 1549-1555
Published online on: 10 March 2015

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Article

Evaluation of the effects of Angelicae dahuricae radix on the morphology and viability of mesenchymal stem cells

Su‑Hyeon Jeong, Bo‑Bae Kim, Ji‑Eun Lee, Youngkyung Ko, Jun‑Beom Park
Pages: 1556-1560
Published online on: 09 March 2015

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Article

MicroRNA-21 promotes osteogenic differentiation by targeting small mothers against decapentaplegic 7

Hongqiu Li, Feng Yang, Zhe Wang, Qin Fu, A Liang
Pages: 1561-1567
Published online on: 17 March 2015

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Article

Association study of polymorphisms in interferon-γ receptor genes with the risk of pulmonary tuberculosis

Joong‑Gon Shin, Byung Lae Park, Lyoung Hyo Kim, Suhg Namgoong, Ji On Kim, Hun Soo Chang, Jong Sook Park, An Soo Jang, Sung Woo Park, Do Jin Kim, Ki Up Kim, Yang Gee Kim, Soo‑Taek Uh, Ki Hyun Seo, Young Hoon Kim, Insong Koh, Choon Sik Park, Hyoung Doo Shin
Pages: 1568-1578
Published online on: 24 March 2015

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Article

Mutations in PTF1A are not a common cause for human VATER/VACTERL association or neural tube defects mirroring Danforth's short tail mouse

Nirmala Gurung, Greta Grosse, Markus Draaken, Alina C. Hilger, Nuzhat Nauman, Andreas Müller, Ulrich Gembruch, Waltraut M. Merz, Heiko Reutter, Michael Ludwig
Pages: 1579-1583
Published online on: 13 March 2015

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Article

Serum microRNA-125a-5p, a useful biomarker in liver diseases, correlates with disease progression

Jianjian Zheng, Zhenxu Zhou, Ziqiang Xu, Guojun Li, Peihong Dong, Zhanguo Chen, Dezhao Lin, Bicheng Chen, Fujun Yu
Pages: 1584-1590
Published online on: 24 March 2015

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Article

Ser49Gly polymorphism in the β-adrenergic receptor 1 gene in a population sample from Rio de Janeiro state, Brazil, stratified by self-identified skin color and genetic ancestry

Kelly T. Santos, Rossana G.A. De Freitas, Fernanda S.N. Manta, Elizeu F. De Carvalho, Dayse A. Silva
Pages: 1591-1597
Published online on: 24 March 2015

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Article

Effects of cinobufacini injection on cell proliferation and the expression of topoisomerases in human HepG‑2 hepatocellular carcinoma cells

Ying Liu, Li‑Ying Ban, Xi Su, Shan Gao, Ji‑Wei Liu, Xiao‑Nan Cui
Pages: 1598-1604
Published online on: 26 March 2015

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Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Article Open Access

Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Article Open Access

Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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Article Open Access

PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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Article Open Access

MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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