|
1
|
Huang LS and Natarajan V: Sphingolipids in
pulmonary fibrosis. Adv Biol Regul. 57C:55–63. 2015. View Article : Google Scholar
|
|
2
|
Marks JH: Update in pulmonary medicine.
Adolesc Med State Art Rev. 24:307–329. 2013.PubMed/NCBI
|
|
3
|
Wynn TA: Integrating mechanisms of
pulmonary fibrosis. J Exp Med. 208:1339–1350. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Tager AM, LaCamera P, Shea BS, et al: The
lysophosphatidic acid receptor LPA (1) links pulmonary fibrosis to
lung injury by mediating fibroblast recruitment and vascular leak.
Nat Med. 14:45–54. 2008. View
Article : Google Scholar
|
|
5
|
Huang LS, Fu P, Patel P, Harijith A, Sun
T, Zhao Y, Garcia JG, Chun J and Natarajan V: Lysophosphatidic acid
receptor 2 deficiency confers protection against bleomycin-induced
lung injury and fibrosis in mice. Am J Respir Cell Mol Biol.
49:912–922. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Huang LS, Berdyshev E, Mathew B, et al:
Targeting sphingosine kinase 1 attenuates bleomycin-induced
pulmonary fibrosis. FASEB J. 27:1749–1760. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Natarajan V, Dudek SM, Jacobson JR, et al:
Sphingosine-1-phosphate, FTY720 and sphingosine-1-phosphate
receptors in the pathobiology of acute lung injury. Am J Respir
Cell Mol Biol. 49:6–17. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Bartram U and Speer CP: The role of
transforming growth factor beta in lung development and disease.
Chest. 125:754–765. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Rancoule C, Pradere JP, Gonzalez J, Klein
J, Valet P, Bascands JL, Schanstra JP and Saulnier-Blache JS:
Lysophosphatidic acid-1-receptor targeting agents for fibrosis.
Expert Opin Investig Drugs. 20:657–667. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Johnson M, Sharma M and Henderson BR:
IQGAP1 regulation and roles in cancer. Cell Signall. 21:1471–1478.
2009. View Article : Google Scholar
|
|
11
|
Nabeshima K, Shimao Y, Inoue T and Koono
M: Immunohistochemical analysis of IQGAP1 expression in human
colorectal carcinomas: its overexpression in carcinomas and
association with invasion fronts. Cancer Lett. 176:101–109. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Clark EA, Golub TR, Lander ES and Hynes
RO: Genomic analysis of metastasis reveals an essential role for
RhoC. Nature. 406:532–535. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
13
|
Brown MD and Sacks DB: IQGAP1 in cellular
signaling: bridging the GAP. Trends Cell Biol. 16:242–249. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Takemoto H, Doki Y, Shiozaki H, Imamura H,
Utsunomiya T, Miyata H, Yano M, Inoue M, Fujiwara Y and Monden M:
Localization of IQGAP1 is inversely correlated with intercellular
adhesion mediated by e-cadherin in gastric cancers. Int J Cancer.
91:783–788. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liu C, Billadeau DD, Abdelhakim H, Leof E,
Kaibuchi K, Bernabeu C, Bloom GS, Yang L, Boardman L, Shah VH and
Kang N: IQGAP1 suppresses TbetaRII-mediated myofibroblastic
activation and metastatic growth in liver. J Clin Invest.
123:1138–1156. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
16
|
Bogatkevich GS, Ludwicka-Bradley A,
Singleton CB, Bethard JR and Silver RM: Proteomic analysis of
CTGF-activated lung fibroblasts: identification of IQGAP1 as a key
player in lung fibroblast migration. Am J Physiol Lung Cell Mol
Physiol. 295:L603–L611. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Huang LS, Hung ND and SokDEandKim MR:
Lysophosphatidylcholine containing docosahexaenoic acid at the sn-1
position is anti-inflammatory. Lipids. 45:225–236. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Huang LS, Kang JS, Kim MR and Sok DE:
Oxygenation of arachidonoyl lysophospholipids by lipoxygenases from
soybean, porcine leukocyte, or rabbit reticulocyte. J Agric Food
Chem. 56:1224–1232. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
King TE: Update in pulmonary medicine. Ann
Intern Med. 129:806–812. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wolters PJ, Collard HR and Jones KD:
Pathogenesis of idiopathic pulmonary fibrosis. Annu Rev Pathol.
9:157–79. 2014. View Article : Google Scholar :
|
|
21
|
Weissbach L, Settleman J, Kalady MF,
Snijders AJ, Murthy AE, Yan YX and Bernards A: Identification of a
human rasGAP-related protein containing calmodulin-binding motifs.
J Biol Chem. 269:20517–20521. 1994.PubMed/NCBI
|
|
22
|
Wang S, Watanabe T, Noritake J, Fukata M,
Yoshimura T, Itoh N, Harada T, Nakagawa M, Matsuura Y, Arimura N
and Kaibuchi K: IQGAP3, a novel effector of Rac1 and Cdc42,
regulates neurite outgrowth. J Cell Sci. 120:567–577. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Jadeski L, Mataraza JM, Jeong HW, Li Z and
Sacks DB: IQGAP1 stimulates proliferation and enhances
tumorigenesis of human breast epithelial cells. J Biol Chem.
283:1008–1017. 2008. View Article : Google Scholar
|
|
24
|
Dong PX, Jia N, Xu ZJ, Liu YT, Li DJ and
Feng YJ: Silencing of IQGAP1 by shRNA inhibits the invasion of
ovarian carcinoma HO-8910PM cells in vitro. J Exp Clin Cancer Res:
CR. 27:772008. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ren JG, Li Z and Sacks DB: IQGAP1
modulates activation of B-Raf. Proc Nat Acad Sci USA.
104:10465–10469. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Roy M, Li Z and Sacks DB: IQGAP1 is a
scaffold for mitogen-activated protein kinase signaling. Mol Cell
Biol. 25:7940–7952. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kohno T, Urao N, Ashino T, Sudhahar V,
Inomata H, Yamaoka-Tojo M, McKinney RD, Fukai T and Ushio-Fukai M:
IQGAP1 links PDGF receptor-beta signal to focal adhesions involved
in vascular smooth muscle cell migration: role in neointimal
formation after vascular injury. Am J Physiol Cell Physiol.
305:C591–C600. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wang Y, Wang M, Wang F, Zhu M, Ma Y, Wang
X and Wu R: IQGAP1 promotes cell proliferation and is involved in a
phosphorylation-dependent manner in wound closure of bronchial
epithelial cells. Int J Mol Med. 22:79–87. 2008.PubMed/NCBI
|
|
29
|
Huang LS, Kim MR and Sok DE: Linoleoyl
lysophosphatidylcholine is an efficient substrate for soybean
lipoxygenase-1. Arch Biochem Biophys. 455:119–126. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Huang LS, Kim MR and Sok DE: Oxygenation
of 1-docosahexaenoyl lysophosphatidylcholine by lipoxygenases;
conjugated hydroperoxydiene and dihydroxytriene derivatives.
Lipids. 42:981–990. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Huang LS, Kim MR and Sok DE: Regulation of
lipoxygenase activity by polyunsaturated lysophosphatidylcholines
or their oxygenation derivatives. J Agric Food Chem. 56:7808–7814.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Huang LS, Kim MR and Sok DE: Enzymatic
reduction of polyunsaturated lysophosphatidylcholine hydroperoxides
by glutathione peroxidase-1. Eur J Lipid Sci Tech. 111:584–592.
2009. View Article : Google Scholar
|
|
33
|
Huang LS, Mathew B, Li H, et al: The
mitochondrial cardiolipin remodeling enzyme lysocardiolipin
acyltransferase is a novel target in pulmonary fibrosis. Am J
Respir Crit Care Med. 189:1402–1415. 2014. View Article : Google Scholar : PubMed/NCBI
|
