|
1
|
Wan J, Ma J, Mei J and Shan G: The effects
of HIF-1alpha on gene expression profiles of NCI-H446 human small
cell lung cancer cells. J Exp Clin Cancer Res. 28:1502009.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wan J, Chai H, Yu Z, et al: HIF-1alpha
effects on angiogenic potential in human small cell lung carcinoma.
J Exp Clin Cancer Res. 30:772011. View Article : Google Scholar
|
|
3
|
Lee GW, Go SI, Cho YJ, et al:
Hypoxia-inducible factor-1alpha and excision repair
cross-complementing 1 in patients with small cell lung cancer who
received front-line platinum-based chemotherapy: a retrospective
study. J Thorac Oncol. 7:528–534. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ioannou M, Papamichali R, Kouvaras E, et
al: Hypoxia inducible factor-1 alpha and vascular endothelial
growth factor in biopsies of small cell lung carcinoma. Lung.
187:321–329. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Zhang W, Zhang H and Xing L: Antisense
oligonucleotide of hypoxia-inducible factor-1alpha suppresses
growth and tumorigenicity of lung cancer cells A549. J Huazhong
Univ Sci Technolog Med Sci. 26:448–450. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lee JW, Bae SH, Jeong JW, Kim SH and Kim
KW: Hypoxia-inducible factor (HIF-1)alpha: its protein stability
and biological functions. Exp Mol Med. 36:1–12. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kappler M, Taubert H, Schubert J,
Vordermark D and Eckert AW: The real face of HIF1alpha in the tumor
process. Cell Cycle. 11:3932–3936. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Park KW, Nozell SE and Benveniste EN:
Protective role of STAT3 in NMDA and glutamate-induced neuronal
death: negative regulatory effect of SOCS3. PLoS One. 7:e508742012.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhang S, Guo D, Jiang L, Zhang Q, Qiu X
and Wang E: SOCS3 inhibiting migration of A549 cells correlates
with PYK2 signaling in vitro. BMC Cancer. 8:1502008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Baltayiannis G, Baltayiannis N and Tsianos
EV: Suppressors of cytokine signaling as tumor repressors.
Silencing of SOCS3 facilitates tumor formation and growth in lung
and liver. J BUON. 13:263–265. 2008.PubMed/NCBI
|
|
11
|
Tokita T, Maesawa C, Kimura T, et al:
Methylation status of the SOCS3 gene in human malignant melanomas.
Int J Oncol. 30:689–694. 2007.PubMed/NCBI
|
|
12
|
Tischoff I, Hengge UR, Vieth M, et al:
Methylation of SOCS-3 and SOCS-1 in the carcinogenesis of Barrett’s
adenocarcinoma. Gut. 56:1047–1053. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yu ZB, Bai L, Qian P, et al: Restoration
of SOCS3 suppresses human lung adenocarcinoma cell growth by
downregulating activation of Erk1/2, Akt apart from STAT3. Cell
Biol Int. 33:995–1001. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Tokunaga E, Oki E, Egashira A, et al:
Deregulation of the Akt pathway in human cancer. Curr Cancer Drug
Targets. 8:27–36. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Dillon RL, White DE and Muller WJ: The
phosphatidyl inositol 3-kinase signaling network: implications for
human breast cancer. Oncogene. 26:1338–1345. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Campbell IG, Russell SE, Choong DY, et al:
Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer
Res. 64:7678–7681. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zhang T, Cui GB, Zhang J, et al:
Inhibition of PI3 kinases enhances the sensitivity of non-small
cell lung cancer cells to ionizing radiation. Oncol Rep.
24:1683–1689. 2010.PubMed/NCBI
|
|
18
|
Littlefield SL, Baird MC, Anagnostopoulou
A and Raptis L: Synthesis, characterization and Stat3 inhibitory
properties of the prototypical platinum(IV) anticancer drug,
[PtCl3(NO2) (NH3)2] (CPA-7). Inorg Chem. 47:2798–2804. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Xu Q, Briggs J, Park S, et al: Targeting
Stat3 blocks both HIF-1 and VEGF expression induced by multiple
oncogenic growth signaling pathways. Oncogene. 24:5552–5560. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Weber A, Hengge UR, Bardenheuer W, et al:
SOCS-3 is frequently methylated in head and neck squamous cell
carcinoma and its precursor lesions and causes growth inhibition.
Oncogene. 24:6699–6708. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Liu Q, Li G, Li R, et al: IL-6 promotion
of glioblastoma cell invasion and angiogenesis in U251 and T98G
cell lines. J Neurooncol. 100:165–176. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kumar K, Wigfield S, Gee HE, et al:
Dichloroacetate reverses the hypoxic adaptation to bevacizumab and
enhances its antitumor effects in mouse zenografts. J Mol Med
(Berl). 91:749–758. 2013. View Article : Google Scholar
|
|
23
|
Kimbro KS and Simons JW: Hypoxia-inducible
factor-1 in human breast and prostate cancer. Endocr Relat Cancer.
13:739–749. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Fraga A, Ribeiro R and Medeiros R: Tumor
hypoxia: the role of HIF. Actas Urol Esp. 33:941–951. 2009.In
Spanish. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Shi YH and Fang WG: Hypoxia-inducible
factor-1 in tumour angiogenesis. World J Gastroenterol.
10:1082–1087. 2004.PubMed/NCBI
|
|
26
|
Fan LF, Diao LM, Chen DJ, et al:
Expression of HIF-1 alpha and its relationship to apoptosis and
proliferation in lung cancer. Ai Zheng. 21:254–258. 2002.In
Chinese. PubMed/NCBI
|
|
27
|
Zhang S, Wang W, Wang E and Qiu X: SOCS3
expression is inversely correlated with Pyk2 in non-small cell lung
cancer and exogenous SOCS3 inhibits proliferation and invasion of
A549 cells. Pathology. 44:434–440. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
He B, You L, Uematsu K, et al: SOCS-3 is
frequently silenced by hypermethylation and suppresses cell growth
in human lung cancer. Proc Natl Acad Sci USA. 100:14133–14138.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Shouda T, Hiraoka K, Komiya S, et al:
Suppression of IL-6 production and proliferation by blocking STAT3
activation in malignant soft tissue tumor cells. Cancer Lett.
231:176–184. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yokogami K: Hypoxia-induced decreases in
SOCS3 increase STAT3 activation and upregulate VEGF gene
expression. Brain Tumor Pathol. 30:135–143. 2013. View Article : Google Scholar
|
|
31
|
Shen A, Chen Y, Hong F, et al: Pien Tze
Huang suppresses IL-6-inducible STAT3 activation in human colon
carcinoma cells through induction of SOCS3. Oncol Rep.
28:2125–2130. 2012.PubMed/NCBI
|
|
32
|
Francipane MG, Eterno V, Spina V, et al:
Suppressor of cytokine signaling 3 sensitizes anaplastic thyroid
cancer to standard chemotherapy. Cancer Res. 69:6141–6148. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yu H and Jove R: The STATs of cancer - new
molecular targets come of age. Nat Rev Cancer. 4:97–105. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Yamasaki M, Nomura T, Sato F and Mimata H:
Chronic hypoxia induces androgen-independent and invasive behavior
in LNCaP human prostate cancer cells. Urol Oncol. 31:1124–1131.
2013. View Article : Google Scholar
|
|
35
|
Yang CL, Liu YY, Ma YG, et al: Curcumin
blocks small cell lung cancer cells migration, invasion,
angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3
signalling pathway. PLoS One. 7:e379602012. View Article : Google Scholar : PubMed/NCBI
|
