|
1
|
Zogragos GN, Farfaras A, Zagouri F,
Chrysikos D and Karaliotas K: Cholangiocarcinoma: principles and
current trends. Hepatobiliary Pancreat Dis Int. 10:10–20. 2011.
View Article : Google Scholar
|
|
2
|
Razumilava N and Gores GJ: Classification,
diagnosis and management of cholangiocarcinoma. Clin Gastroenterol
Hepatol. 11:13–21. 2013. View Article : Google Scholar
|
|
3
|
Rattanasinganchan P, Leelawat K,
Treepongkaruna SA, Tocharoentanaphol C, Subwongcharoen S,
Suthiphongchai T and Tohtong R: Establishment and characterization
of a cholan-giocarcinoma cell line (RMCCA-1) from a Thai patient.
World J Gastroenterol. 12:6500–6506. 2006.PubMed/NCBI
|
|
4
|
Friman S: Cholangiocarcinoma-current
treatment options. Scand J Surg. 100:30–34. 2011.
|
|
5
|
Miyoshi A, Kitajima Y, Ide T, et al:
Hypoxia accelerates cancer invasion of hepatoma cells by
upregulating MMP expression in an HIF-1α-independent manner. Int J
Oncol. 29:1533–1539. 2006.PubMed/NCBI
|
|
6
|
Yokoi K and Fidler IJ: Hypoxia increases
resistance of human pancreatic cancer cells to apoptosis induced by
gemcitabine. Clin Cancer Res. 10:2299–2306. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kim JY, Kim YJ, Lee S and Park JH: The
critical role of ERK in death resistance and invasiveness of
hypoxia-selected glioblastoma cells. BMC Cancer. 9:272009.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kitajima Y, Ide T, Ohtsuka T and Miyazaki
K: Induction of hepatocyte growth factor activator gene expression
under hypoxia activates the hepatocyte growth factor/c-Met system
via hypoxia inducible factor-1 in pancreatic cancer. Cancer Sci.
99:1341–1347. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Koh MY, Lemos R Jr, Lui X and Powis G: The
hypoxia-associated factor switches cells from HIF-1α- to
HIF-2α-dependent signaling promoting stem cell characteristics,
aggressive tumor growth and invasion. Cancer Res. 71:4015–4027.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Fu OY, Hou MF, Yang SF, Huang SC and Lee
WY: Cobalt chloride-induced hypoxia modulates the invasive
potential and matrix matelloproteinases of primary and metastatic
breast cancer cells. Anticancer Res. 29:3131–3138. 2009.PubMed/NCBI
|
|
11
|
Pennacchietti S, Michieli P, Galluzzo M,
Mazzone M, Giordano S and Comoglio PM: Hypoxia promotes invasive
growth by transcriptional activation of the met protooncogene.
Cancer Cell. 3:347–361. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Cecchi F, Rabe DC and Bottaro DP:
Targeting the HGF/Met signaling pathway in cancer. Eur J Cancer.
46:1260–1270. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Socoteanu MP, Mott F, Alpini G and Frankel
AE: c-Met targeted therapy of cholangiocarcinoma. World J
Gastroenterol. 14:2990–2994. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Matsumura A, Kubota T, Taiyoh H, et al:
HGF regulates VEGF expression via the c-Met receptor downstream
pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells. Int J
Oncol. 42:535–542. 2013.
|
|
15
|
Leelawat K, Leelawat S, Tepaksorn P,
Rattanasinganchan P, Leungchaweng A, Tohtong R and Sobhon P:
Involvement of c-Met/hepatocyte growth factor pathway in
cholangiocarcinoma cell invasion and its therapeutic inhibition
with small interfering RNA specific for c-Met. J Surg Res.
136:78–84. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Santarpia L, Lippman SL and El-Naggar AK:
Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy.
Expert Opin Ther Targets. 16:103–119. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Katz M, Amit I and Yarden Y: Regulation of
MAPKs by growth factors and receptor tyrosine kinases. Biochim
Biophys Acta. 1773:1161–1176. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lee JW, Bae SH, Jeong JW, Kim SH and Kim
KW: Hypoxia-inducible factor (HIF-1)α: its protein stability and
biological functions. Exp Mol Med. 36:1–12. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Harris AL: Hypoxia-a key regulatory factor
in tumour growth. Nat Rev Cancer. 2:38–47. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Organ SL and Tsao MS: An overview of the
Met signaling pathway. Ther Adv Med Oncol. 3(Suppl 1): S7–S19.
2011. View Article : Google Scholar
|
|
21
|
Seubwai W, Kraiklang R, Wongkham C and
Wongkham S: Hypoxia enhances aggressiveness of cholangiocarcinoma
cells. Asian Pac J Cancer Prev. 13(Suppl): 53–58. 2012.PubMed/NCBI
|
|
22
|
Gwak GY, Yoon JH, Kim KM, Lee HS, Chung JW
and Gores GJ: Hypoxia stimulates proliferation of human hepatoma
cells through the induction of hexokinase II expression. J Hepatol.
42:358–364. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
He G, Jiang Y, Zhang B and Wu G: The
effect of HIF-1α on glucose metabolism, growth and apoptosis of
pancreatic cancerous cells. Asia Pac J Clin Nutr. 23:174–180.
2014.
|
|
24
|
Dai R, Li J, Fu J, et al: The tyrosine
kinase c-Met contributes to the pro-tumorigenic function of the p38
kinase in human bile duct cholangiocarcinoma cells. J Biol Chem.
287:39812–39823. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Xu L, Nilsson MB, Saintigny P, et al:
Epidermal growth factor receptor regulates MET levels and
invasiveness through hypoxia-inducible factor-1α in non-small cell
lung cancer cells. Oncogene. 29:2616–2627. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mylonis I, Chachami G, Samiotaka M, et al:
Identification of MAPK phosphorylation sites and their role in the
localization and activity of hypoxia-inducible factor-1α. J Biol
Chem. 281:33095–33106. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lee KH, Choi EY, Hyun MS and Kim JR:
Involvement of MAPK pathway in hypoxia-induced up-regulation of
urokinase plasminogen activator receptor in a human prostatic
cancer cell line, PC3MLN4. Exp Mol Med. 36:57–64. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Mazzone M and Comoglio PM: The Met
pathway: master switch and drug target in cancer progression. FASEB
J. 20:1611–1621. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Eckerich C, Zapf S, Fillbrandt R, Loges S,
Westphat M and Lamszus K: Hypoxia can induce c-Met expression in
glioma cells and enhance SF/HGF-induced cell migration. Int J
Cancer. 121:276–283. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Sullivan R and Graham CH: Hypoxia-driven
selection of the metastatic phenotype. Cancer Metastasis Rev.
26:319–331. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Hara S, Nakashiro K, Klosek SK, Ishikawa
T, Shintani S and Hamakawa H: Hypoxia enhances c-Met/HGF receptor
expression and signaling by activating HIF-1alpha in human salivary
gland cancer cells. Oral Oncol. 42:593–598. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wang Y, Li Z, Zhang H, et al: HIF-1α and
HIF-2α correlate with migration and invasion in gastric cancer.
Cancer Biol Ther. 10:376–382. 2010. View Article : Google Scholar : PubMed/NCBI
|
