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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2015 Volume 12 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Epigenetic alterations in gastric cancer (Review)

Du-Guan Fu
Pages: 3223-3230
Published online on: 22 May 2015

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Review

Future opportunities in preventing ototoxicity: Caffeic acid phenethyl ester may be a candidate (Review)

Sumeyya Akyol, Bunyamin Isik, Aynur Altuntas, Gonul Erden, Ozlem Cakmak, S. Fatih Kurşunlu, Bahattin Adam, Omer Akyol
Pages: 3231-3235
Published online on: 14 May 2015

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Article Open Access

Drug exposure in a metastatic human lung adenocarcinoma cell line gives rise to cells with differing adhesion, proliferation, and gene expression: Implications for cancer chemotherapy

Huiling Li, Jianxing He, Nanshan Zhong, Robert M. Hoffman
Pages: 3236-3242
Published online on: 25 May 2015

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Article Open Access

Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation

Yao‑Dong Li, Yi‑Fan Hong, Yueerguli Yusufuaji, Bao‑Peng Tang, Xian‑Hui Zhou, Guo‑Jun Xu, Jin‑Xin Li, Lin Sun, Jiang‑Hua Zhang, Qiang Xin, Jian Xiong, Yu‑Tong Ji, Yu Zhang
Pages: 3243-3248
Published online on: 25 May 2015

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Article Open Access

Dasatinib enhances antitumor activity of paclitaxel in ovarian cancer through Src signaling

Juan Xiao, Manman Xu, Teng Hou, Yongwen Huang, Chenlu Yang, Jundong Li
Pages: 3249-3256
Published online on: 14 May 2015

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Article Open Access

Molecular and cellular mechanisms of tight junction dysfunction in the irritable bowel syndrome

Peng Cheng, Jianning Yao, Chunfeng Wang, Lianfeng Zhang, Wuming Kong
Pages: 3257-3264
Published online on: 21 May 2015

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Article Open Access

Hypoxia enhances cholangiocarcinoma invasion through activation of hepatocyte growth factor receptor and the extracellular signal‑regulated kinase signaling pathway

Thitinee Vanichapol, Kawin Leelawat, Suradej Hongeng
Pages: 3265-3272
Published online on: 27 May 2015

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Article Open Access

Toxicity of nickel ions and comprehensive analysis of nickel ion‑associated gene expression profiles in THP‑1 cells

Ying Zhang, Zhi‑Wei Zhang, Yu‑Mei Xie, Shu‑Shui Wang, Qing‑Huan Qiu, Ying‑Ling Zhou, Guo‑Hong Zeng
Pages: 3273-3278
Published online on: 03 June 2015

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Article Open Access

Hereditary protein S deficiency leads to ischemic stroke

Zhao‑Hui Wang, Zhi‑Jun Zhao, Kang Xu, Guo‑Bing Sun, Lin Song, Hong‑Xiang Yin, Xiao‑Qi Chen
Pages: 3279-3284
Published online on: 18 May 2015

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Article Open Access

Association of the angiopoietin-like protein 8 rs2278426 polymorphism and several environmental factors with serum lipid levels

Tao Guo, Rui‑Xing Yin, Jian Wu, Quan‑Zhen Lin, Guang‑Yuan Shi, Shao‑Wen Shen, Jia‑Qi Sun, Hui Li, Wei‑Xiong Lin, De‑Zhai Yan
Pages: 3285-3296
Published online on: 25 May 2015

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Article Open Access

Comparison of the neuropsychological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate receptor antagonist against electroconvulsive therapy-induced learning and memory impairment in depressed rats

Gang Liu, Chao Liu, Xue‑Ning Zhang
Pages: 3297-3308
Published online on: 21 May 2015

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Article Open Access

Continuous expression of CD83 on activated human CD4+ T cells is correlated with their differentiation into induced regulatory T cells

Liwen Chen, Shihe Guan, Qiang Zhou, Shouqin Sheng, Fei Zhong, Qin Wang
Pages: 3309-3314
Published online on: 18 May 2015

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Article Open Access

Inflammation and oxidative stress, rather than hypoxia, are predominant factors promoting angiogenesis in the initial phases of atherosclerosis

Weigang Xiao, Zhenhua Jia, Qiuyan Zhang, Cong Wei, Hongtao Wang, Yiling Wu
Pages: 3315-3322
Published online on: 19 May 2015

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Article Open Access

Profiling circulating microRNAs in maternal serum and plasma

Qinyu Ge, Yanting Shen, Fei Tian, Jiafeng Lu, Yunfei Bai, Zuhong Lu
Pages: 3323-3330
Published online on: 03 June 2015

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Article Open Access

Isolation, in vitro culture and identification of a new type of mesenchymal stem cell derived from fetal bovine lung tissues

Pengfei Hu, Yabin Pu, Xiayun Li, Zhiqiang Zhu, Yuhua Zhao, Weijun Guan, Yuehui Ma
Pages: 3331-3338
Published online on: 27 May 2015

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Article Open Access

Activation of autophagy in rat brain cells following focal cerebral ischemia reperfusion through enhanced expression of Atg1/pULK and LC3

Jingwei Yu, Cuifen Bao, Yanru Dong, Xia Liu
Pages: 3339-3344
Published online on: 26 May 2015

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Article Open Access

MicroRNA-26a-modified adipose-derived stem cells incorporated with a porous hydroxyapatite scaffold improve the repair of bone defects

Zhenlin Wang, Dawei Zhang, Zhiqiang Hu, Jiwei Cheng, Chuanmeng Zhuo, Xiancong Fang, Yongming Xing
Pages: 3345-3350
Published online on: 18 May 2015

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Article Open Access

Endogenous hydrogen sulfide is associated with angiotensin II type 1 receptor in a rat model of carbon tetrachloride‑induced hepatic fibrosis

Hui‑Ning Fan, Ni‑Wei Chen, Wei‑Lin Shen, Xiang‑Yun Zhao, Jing Zhang
Pages: 3351-3358
Published online on: 02 June 2015

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Article Open Access

Overexpression of miR‑199b‑5p inhibits Ewing's sarcoma cell lines by targeting CCNL1

Weihua Li, Yuxia Li, Jiankuo Guo, Huagang Pan, Yongle Zhang, Xiao Wang
Pages: 3359-3364
Published online on: 03 June 2015

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Article Open Access

Hypoxia-inducible factor-1α and Wnt/β-catenin signaling pathways promote the invasion of hypoxic gastric cancer cells

Hong‑Lan Liu, Dang Liu, Guang‑Rong Ding, Peng‑Fei Liao, Jun‑Wen Zhang
Pages: 3365-3373
Published online on: 21 May 2015

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Article Open Access

Doxycycline inhibits leukemic cell migration via inhibition of matrix metalloproteinases and phosphorylation of focal adhesion kinase

Chunhuai Wang, Ru Xiang, Xiangzhong Zhang, Yunxian Chen
Pages: 3374-3380
Published online on: 25 May 2015

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Article Open Access

GSK1904529A, an insulin‑like growth factor‑1 receptor inhibitor, inhibits glioma tumor growth, induces apoptosis and inhibits migration

Qiang Zhou, Junxia Zhang, Qinying Cui, Xiaodong Li, Ge Gao, Yanfen Wang, Yuping Xu, Xiaoqun Gao
Pages: 3381-3385
Published online on: 28 May 2015

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Article Open Access

Identification of genes associated with laryngeal squamous cell carcinoma samples based on bioinformatic analysis

Bo Yang, Xueli Bao
Pages: 3386-3392
Published online on: 18 May 2015

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Article Open Access

Expression and clinical significance of hypoxia-inducible factor 1α, Snail and E-cadherin in human ovarian cancer cell lines Retraction in /10.3892/mmr.2025.13638

Yan Zhang, Nina Fan, Jing Yang
Pages: 3393-3399
Published online on: 14 May 2015

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Article Open Access

Sanguinarine inhibits angiotensin II‑induced apoptosis in H9c2 cardiac cells via restoring reactive oxygen species‑mediated decreases in the mitochondrial membrane potential

Yuan Liu, Rong Jiao, Zhen‑Guo Ma, Wei Liu, Qing‑Qing Wu, Zheng Yang, Fang‑Fang Li, Yuan Yuan, Zhou‑Yan Bian, Qi‑Zhu Tang
Pages: 3400-3408
Published online on: 25 May 2015

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Article Open Access

Overexpression of caudal‑related homeobox transcription factor 2 inhibits the growth of transplanted colorectal tumors in nude mice

Jian‑Bao Zheng, Li‑Na Qiao, Xue‑Jun Sun, Jie Qi, Hai‑Liang Ren, Guang‑Bing Wei, Pei‑Hua Zhou, Jian‑Feng Yao, Li Zhang, Peng‑Bo Jia
Pages: 3409-3415
Published online on: 25 May 2015

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Article Open Access

MicroRNA-141 inhibits migration of gastric cancer by targeting zinc finger E-box-binding homeobox 2

Ying Du, Lingfei Wang, Honghai Wu, Yiyin Zhang, Kan Wang, Dingting Wu
Pages: 3416-3422
Published online on: 15 May 2015

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Article Open Access

Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells

Longfeng Sun, Gang Li, Bing Dai, Wei Tan, Hongwen Zhao, Xiaofei Li, Aiping Wang
Pages: 3423-3431
Published online on: 03 June 2015

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Article Open Access

Role of hypoxia-inducible factor-1α and CD146 in epidermal growth factor receptor-mediated angiogenesis in salivary gland adenoid cystic carcinoma

Wei‑Ming Wang, Zhi‑Li Zhao, Wen‑Feng Zhang, Yi‑Fang Zhao, Lu Zhang, Zhi‑Jun Sun
Pages: 3432-3438
Published online on: 22 May 2015

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Article Open Access

Integrative meta-analysis of differentially expressed genes in osteoarthritis using microarray technology

Xi Wang, Yujie Ning, Xiong Guo
Pages: 3439-3445
Published online on: 15 May 2015

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Article Open Access

Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways

Yong‑Seok Han, Jun Hee Lee, Sang Hun Lee
Pages: 3446-3452
Published online on: 21 May 2015

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Article Open Access

Inhibition of liver fibrosis using vitamin A‑coupled liposomes to deliver matrix metalloproteinase‑2 siRNA in vitro

Yiping Li, Feng Liu, Fengan Ding, Pingsheng Chen, Meng Tang
Pages: 3453-3461
Published online on: 25 May 2015

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Article Open Access

LW6, a hypoxia‑inducible factor 1 inhibitor, selectively induces apoptosis in hypoxic cells through depolarization of mitochondria in A549 human lung cancer cells

Mariko Sato, Katsumi Hirose, Ikuo Kashiwakura, Masahiko Aoki, Hideo Kawaguchi, Yoshiomi Hatayama, Hiroyoshi Akimoto, Yuichiro Narita, Yoshihiro Takai
Pages: 3462-3468
Published online on: 27 May 2015

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Article Open Access

Mutation analysis of two families with inherited congenital cataracts

Chang Liang, Han Liang, Yu Yang, Liu Ping, Qiao Jie
Pages: 3469-3475
Published online on: 22 May 2015

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Article Open Access

Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels

Jian Wu, Rui-Xing Yin, Tao Guo, Quan-Zhen Lin, Shao-Wen Shen, Jia-Qi Sun, Guang-Yuan Shi, Jin-Zhen Wu, De-Zhai Yang, Wei-Xiong Lin
Pages: 3476-3486
Published online on: 22 May 2015

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Article Open Access

Functional characterization of the nitrogen permease regulator‑like‑2 candidate tumor suppressor gene in colorectal cancer cell lines Retraction in /10.3892/mmr.2023.13088

Ai‑Yun Liu, Ming‑Na Liu, Feng‑Hua Pei, Jing Chen, Xin‑Hong Wang, Dan Liu, Ya‑Ju Du, Bing‑Rong Liu
Pages: 3487-3493
Published online on: 03 June 2015

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Article Open Access

Effects of oestrogen deficiency on the alveolar bone of rats with experimental periodontitis

Xin‑Chen Xu, Hui Chen, Xi Zhang, Zan‑Jing Zhai, Xu‑Qiang Liu, Xin‑Yi Zheng, Jun Zhang, An Qin, Er‑Yi Lu
Pages: 3494-3502
Published online on: 02 June 2015

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Article

Hepatitis B virus upregulates the expression of kinesin family member 4A

Cheng‑Liang Zhu, Duo‑Zhi Cheng, Fang Liu, Xiao‑Hong Yan, Kai‑Lang Wu, Fu‑Bing Wang, Xing‑Hui Liu
Pages: 3503-3507
Published online on: 15 May 2015

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Article

Effects of estrogen deficiency on microstructural changes in rat alveolar bone proper and periodontal ligament

Zhongshuang Liu, Lisha Liu, Chen Kang, Qi Xie, Bin Zhang, Ying Li
Pages: 3508-3514
Published online on: 04 June 2015

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Article

Toll‑like receptor 7/8 agonist, R848, exhibits antitumoral effects in a breast cancer model

Tao Yin, Sisi He, Yongsheng Wang
Pages: 3515-3520
Published online on: 03 June 2015

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Article

Determination of whether screening tests for chronic atrophic gastritis really has a positive predictive value

Flaviano Di Paola, Valentina D'Angelo, Fabiana Tatangelo, Vittoria Barchiesi, Marianna Rizzo, Monica Cantile, Gerardo Botti, Ernesta Cavalcanti
Pages: 3521-3524
Published online on: 02 June 2015

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Article

Identification of a microRNA signature in endothelial cells with mechanical stretch stimulation

Jubing Zheng, Kui Zhang, Yueli Wang, Jian Cao, Feng Zhang, Qiwen Zhou, Ran Dong
Pages: 3525-3530
Published online on: 25 May 2015

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Article

Isolation and phenotypic characterization of cancer stem-like side population cells in colon cancer

Long Feng, Jian‑Bing Wu, Feng‑Ming Yi
Pages: 3531-3536
Published online on: 19 May 2015

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Article

Macrocalyxin A inhibits proliferation and induces apoptosis of t (8;21) leukemia cells through mitochondrial signaling pathways and regulates AML‑ETO mRNA expression

Zhenni Wang, Yaping Lv, Jun Xia, Hao Shi, Weizhong Wang, Yonglie Zhou
Pages: 3537-3542
Published online on: 27 May 2015

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Article

Let-7i inhibits the malignant phenotype of osteosarcoma cells by targeting Aurora-B

Guo Mei Zhang, Xin Hua Long, Jia Ming Liu, Liang Bo Zhu, Xuan Yin Chen, Shan Hu Huang, Zhi Hong Zhang, Zhi Li Liu
Pages: 3543-3548
Published online on: 18 May 2015

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Article

Beneficial effects of the traditional medicine Igongsan and its constituent ergosterol on dextran sulfate sodium-induced colitis in mice

Su‑Jin Kim, Hyun‑Ji Shin, Geun‑Hyuk Lee, Dae‑Seung Kim, Hye‑Lin Kim, Jinbong Park, Yunu Jung, Dong‑Hyun Youn, Jongwook Kang, Seung‑Heon Hong, Jae‑Young Um
Pages: 3549-3556
Published online on: 22 May 2015

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Article

Ginsenoside Rg3 induces apoptosis in human multiple myeloma cells via the activation of Bcl-2-associated X protein

Yun Luo, Ping Zhang, Han‑Qing Zeng, Shi‑Feng Lou, Dao‑Xin Wang
Pages: 3557-3562
Published online on: 19 May 2015

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Article

Inhibition of SHP-2 promotes radiosensitivity in glioma

Quanye Sun, Luyan Mu, Wanchen Qiao, Hui Li, Jiabin Tang, Ce Wang, Wei Hu, Tianshu Zhao, Baijing Dong, Yuwen Song, Xiaoqian Liu
Pages: 3563-3568
Published online on: 25 May 2015

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Article

Has‑miR‑125a and 125b are induced by treatment with cisplatin in nasopharyngeal carcinoma and inhibit apoptosis in a p53‑dependent manner by targeting p53 mRNA

Jian Jun Chen, Shi Xi Liu, Mian Zhi Chen, Zi Yi Zhao
Pages: 3569-3574
Published online on: 27 May 2015

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Article

Role of HER-2 activity in the regulation of malignant meningioma cell proliferation and motility

Weijia Wang, Yi Tu, Shanshan Wang, Shan Xu, Linlin Xu, Yifeng Xiong, Jinhong Mei, Chunliang Wang
Pages: 3575-3582
Published online on: 21 May 2015

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Article

Positive shift of Nav1.8 current inactivation curve in injured neurons causes neuropathic pain following chronic constriction injury

Guixia Li, Xifang Liu, Jingnan Du, Jianzhao Chen, Fenglin She, Chunfu Wu, Chunli Li
Pages: 3583-3590
Published online on: 25 May 2015

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Article

Vaccination with ubiquitin-hepatitis B core antigen-cytoplasmic transduction peptide enhances the hepatitis B virus-specific cytotoxic T-lymphocyte immune response and inhibits hepatitis B virus replication in transgenic mice

Meng Zhuo, Linlin Song, Yuyan Tang, Shenglan Dai, Xiaohua Chen, Yongsheng Yu, Guoqing Zang, Zhenghao Tang
Pages: 3591-3598
Published online on: 25 May 2015

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Article

Oxidized‑low density lipoprotein accumulates cholesterol esters via the PKCα‑adipophilin‑ACAT1 pathway in RAW264.7 cells Retraction in /10.3892/mmr.2023.12965

Yuncheng Qiao, Dongming Guo, Lei Meng, Qingnan Liu, Xiaohui Liu, Chaoke Tang, Guanghui Yi, Zuo Wang, Weidong Yin, Guoping Tian, Zhonghua Yuan
Pages: 3599-3606
Published online on: 27 May 2015

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Article

Loquat (Eriobotrya japonica) extract prevents dexamethasone-induced muscle atrophy by inhibiting the muscle degradation pathway in Sprague Dawley rats

Kyung Kyun Noh, Ki Wung Chung, Bokyung Sung, Min Jo Kim, Chan Hum Park, Changshin Yoon, Jae Sue Choi, Mi Kyung Kim, Cheol Min Kim, Nam Deuk Kim, Hae Young Chung
Pages: 3607-3614
Published online on: 22 May 2015

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Article

Adrenomedullin improves intestinal epithelial barrier function by downregulating myosin light chain phosphorylation in ulcerative colitis rats

Zaifeng Yi, Heng Fan, Xingxing Liu, Qing Tang, Dongmei Zuo, Jia Yang
Pages: 3615-3620
Published online on: 03 June 2015

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Article

Protective effects of ginsenoside Rg1 on aging Sca‑1+ hematopoietic cells

Yue Zhou, Jun Liu, Shizhong Cai, Dianfeng Liu, Rong Jiang, Yaping Wang
Pages: 3621-3628
Published online on: 03 June 2015

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Article

Dermatological disorders in Tuvalu between 2009 and 2012

Li‑Jung Lan, Ying‑Shuang Lien, Shao‑Chuan Wang, Nese Ituaso-Conway, Ming-Che Tsai, Pao-Ying Tseng, Yu‑Lin Yeh, Chun‑Tzu Chen, Ko‑Huang Lue, Jing‑Gung Chung, Yu‑Ping Hsiao
Pages: 3629-3631
Published online on: 21 May 2015

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Article

Effects of astaxanthin on dinitrofluorobenzene-induced contact dermatitis in mice

Hyungwoo Kim, Yong‑Tae Ahn, Guem San Lee, Su In Cho, Jong‑Myoung Kim, Chu Lee, Byung Kwan Lim, Seong‑A Ju, Won Gun An
Pages: 3632-3638
Published online on: 04 June 2015

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Article

Pirfenidone attenuates bladder fibrosis and mitigates deterioration of bladder function in a rat model of partial bladder outlet obstruction

Liu Jian Duan, Jun Qi, Tao Huang, Xin Gu, Ding Xu, Xiang Jie Kong, Xiao Qiang Qian
Pages: 3639-3647
Published online on: 21 May 2015

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Article

Obesity‑associated microRNA‑26b regulates the proliferation of human preadipocytes via arrest of the G1/S transition

Guangfeng Xu, Chenbo Ji, Guixian Song, Chunmei Shi, Yahui Shen, Ling Chen, Lei Yang, Yaping Zhao, Xirong Guo
Pages: 3648-3654
Published online on: 27 May 2015

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Protection of photoreceptors by intravitreal injection of the Y‑27632 Rho‑associated protein kinase inhibitor in Royal College of Surgeons rats

Ting Zhang, Yantao Wei, Xintong Jiang, Jingming Li, Suo Qiu, Shaochong Zhang
Pages: 3655-3661
Published online on: 03 June 2015

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Using exome sequencing to identify the cause of myocardial hypertrophy in a Chinese family

Tian Pu, Qianqian Guo, Ruixue Cao, Rang Xu, Kun Sun, Sun Chen
Pages: 3662-3666
Published online on: 22 May 2015

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Article

Myeloid-derived suppressor cells suppress CD4+ and CD8+ T cell responses in autoimmune hepatitis

Haiwen Li, Fu Dai, Qiong Peng, Huizhong Gan, Jishun Zheng, Yunling Xia, Wanyuan Zhang
Pages: 3667-3673
Published online on: 15 May 2015

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Article

Downregulation of microRNA‑210 inhibits osteosarcoma growth in vitro and in vivo

Changjian Liu, Xin Tang
Pages: 3674-3680
Published online on: 03 June 2015

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Article

Paxilitaxel induces apoptosis accompanied by protective autophagy in osteosarcoma cells through hypoxia‑inducible factor‑1α pathway

Yuanqing Guo, Chuangxin Huang, Guowei Li, Tao Chen, Jinxiang Li, Zongwen Huang
Pages: 3681-3687
Published online on: 27 May 2015

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Article

Neuroprotective effects of quercetin in a mouse model of brain ischemic/reperfusion injury via anti‑apoptotic mechanisms based on the Akt pathway

Xiaoming Lei, Hailian Chao, Zhenni Zhang, Jianrui Lv, Siyuan Li, Haidong Wei, Rongliang Xue, Fang Li, Zongfang Li
Pages: 3688-3696
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Article

Borna disease virus infection impacts microRNAs associated with nervous system development, cell differentiation, proliferation and apoptosis in the hippocampi of neonatal rats

Mingjun Zhao, Lin Sun, Shigang Chen, Dan Li, Liang Zhang, Peng He, Xia Liu, Lujun Zhang, Hong Zhang, Deyu Yang, Rongzhong Huang, Peng Xie
Pages: 3697-3703
Published online on: 25 May 2015

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Article

Dextromethorphan provides neuroprotection via anti-inflammatory and anti-excitotoxicity effects in the cortex following traumatic brain injury

Benfang Pu, Yonghua Xue, Qingming Wang, Chunhui Hua, Xinyuan Li
Pages: 3704-3710
Published online on: 25 May 2015

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Article

MicroRNA-199a induces differentiation of induced pluripotent stem cells into endothelial cells by targeting sirtuin 1

Zhoubin Li, Andriana Margariti, Yutao Wu, Feng Yang, Jian Hu, Li Zhang, Ting Chen
Pages: 3711-3717
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Prevalence and spectrum of LRRC10 mutations associated with idiopathic dilated cardiomyopathy

Xin-Kai Qu, Fang Yuan, Ruo-Gu Li, Lei Xu, Wei-Feng Jing, Hua Liu, Ying-Jia Xu, Min Zhang, Xu Liu, Wei-Yi Fang, Yi-Qing Yang, Xing-Biao Qiu
Pages: 3718-3724
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Article

Intrahepatic transplantation of adipose‑derived stem cells attenuates the progression of non‑alcoholic fatty liver disease in rats

Fan Pan, Naishun Liao, Youshi Zheng, Yingchao Wang, Yunzhen Gao, Sen Wang, Yi Jiang, Xiaolong Liu
Pages: 3725-3733
Published online on: 26 May 2015

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Article

Protective effects of allicin against ischemic stroke in a rat model of middle cerebral artery occlusion

Benping Zhang, Feng Li, Weijiang Zhao, Jiebing Li, Qingsong Li, Weizhi Wang
Pages: 3734-3738
Published online on: 03 June 2015

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Article

Rescue effect of lipid emulsion on bupivacaine‑induced cardiac toxicity in cardiomyocytes

Libin Yang, Zhixia Bai, Danni Lv, Haibo Liu, Xiaohui Li, Xuexin Chen
Pages: 3739-3747
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Article

Induction of apoptosis in oral squamous carcinoma cells by pyrrolo-1,5-benzoxazepines

Kate O'Callaghan, Eleonora Palagano, Stefania Butini, Giuseppe Campiani, D. Clive Williams, Daniela M. Zisterer, Jeff O'Sullivan
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Published online on: 25 May 2015

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Article

Mass spectrometric identification, characterization and validation of the haptoglobin β-chain protein as a lung cancer serum biomarker

Asima Ayyub, Mahjabeen Saleem, Syed Ghulam Musharraf, Mamoona Naz, Asma Tariq, Naghma Hashmi
Pages: 3755-3762
Published online on: 22 May 2015

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Article

Angiotensin II type 1 receptor‑associated protein plays a role in regulating the local renin‑angiotensin system in HSC‑T6 cells

Haiyang Huang, Jie Zhou, Zhonglin Cui, Biao Wang, Yunwei Hu
Pages: 3763-3768
Published online on: 26 May 2015

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Article

Docosahexaenoic acid inhibits the growth of hormone-dependent prostate cancer cells by promoting the degradation of the androgen receptor

Zhimei Hu, Haixia Qi, Ruixue Zhang, Kun Zhang, Zhemin Shi, Yanan Chang, Linfeng Chen, Mohsen Esmaeili, Aria Baniahmad, Wei Hong
Pages: 3769-3774
Published online on: 21 May 2015

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Article

MicroRNA-148a inhibits migration and invasion of ovarian cancer cells via targeting sphingosine-1-phosphate receptor 1 Retraction in /10.3892/mmr.2021.12298

Zhengfang Wen, Shuzhen Zhao, Shanshan Liu, Ying Liu, Xiaorui Li, Shaoru Li
Pages: 3775-3780
Published online on: 25 May 2015

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Article

Vascular endothelial growth factor affects dendritic cell activity in hypertensive disorders of pregnancy

Jing Wang, Yu‑Mei Tao, Xiao‑Yan Cheng, Tian‑Feng Zhu, Zhi‑Fang Chen, Hui Yao, Liang‑Xiang Su
Pages: 3781-3786
Published online on: 14 May 2015

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Article

Reduced expression of HSP27 following HAD-B treatment is associated with Her2 downregulation in NIH:OVCAR-3 human ovarian cancer cells

Kuo Chu Li, Kyun Heo, Nitin Ambade, Min Kyung Kim, Kyung-Hee Kim, Byong Chul Yoo, Hwa-Seung Yoo
Pages: 3787-3794
Published online on: 03 June 2015

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Article

Synuclein-γ promotes migration of MCF7 breast cancer cells by activating extracellular-signal regulated kinase pathway and breaking cell-cell junctions

Qing Zhuang, Caiyun Liu, Like Qu, Chengchao Shou
Pages: 3795-3800
Published online on: 19 May 2015

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Article

Inhibition of FHL1 inhibits cigarette smoke extract-induced proliferation in pulmonary arterial smooth muscle cells

Yuping Li, Guimei Pu, Chengshui Chen, Li Yang
Pages: 3801-3808
Published online on: 14 May 2015

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Article

Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells

Zhenghong Zhang, Xunsheng Pang, Zonghao Tang, Dingzhong Yin, Zhengchao Wang
Pages: 3809-3814
Published online on: 14 May 2015

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Article

Pro-apoptotic and anti-proliferative effects of 3,3'-diindolylmethane in nasopharyngeal carcinoma cells via downregulation of telomerase activity

Fen Li, Yong Xu, Chen Chen, Shi‑Ming Chen, Bo‑Kui Xiao, Ze‑Zhang Tao
Pages: 3815-3820
Published online on: 25 May 2015

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Article

Identification of proteins interacting with protein kinase C‑δ in hyperthermia‑induced apoptosis and thermotolerance of Tca8113 cells

Jianqi Liu, Wenchuan Huang, Yunhong Lin, Li Bian, Yongwen He
Pages: 3821-3828
Published online on: 27 May 2015

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Article

Apelin/APJ signaling promotes hypoxia‑induced proliferation of endothelial progenitor cells via phosphoinositide‑3 kinase/Akt signaling

Jingchang Zhang, Qiming Liu, Xinqun Hu, Zhenfei Fang, Feng Huang, Liang Tang, Shenghua Zhou
Pages: 3829-3834
Published online on: 27 May 2015

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Article

Lycium ruthenicum extract alleviates high-fat diet-induced nonalcoholic fatty liver disease via enhancing the AMPK signaling pathway

Jiayao Lin, Yu Zhang, Xinqing Wang, Wenwen Wang
Pages: 3835-3840
Published online on: 25 May 2015

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Article

Twist promotes invasion and cisplatin resistance in pancreatic cancer cells through growth differentiation factor 15

Hong Ji, Hong‑Wei Lu, Yi‑Ming Li, Le Lu, Jin‑Long Wang, Ya‑Fei Zhang, Hao Shang
Pages: 3841-3848
Published online on: 27 May 2015

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Article

Resveratrol amplifies BMP‑4‑stimulated osteoprotegerin synthesis via p38 MAP kinase in osteoblasts

Gen Kuroyanagi, Haruhiko Tokuda, Naohiro Yamamoto, Rie Matsushima‑Nishiwaki, Jun Mizutani, Osamu Kozawa, Takanobu Otsuka
Pages: 3849-3854
Published online on: 03 June 2015

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Article

Suppressor of cytokine signaling 1-modulated metalloproteinases and tissue inhibitor of metalloproteinase in pulmonary fibrosis

Qiurui Zhang, Yi Guo, Ran Dong, Ranran Dai, Min Zhou
Pages: 3855-3861
Published online on: 21 May 2015

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Article

Rg1 exhibits neuroprotective effects by inhibiting the endoplasmic reticulum stress‑mediated c‑Jun N‑terminal protein kinase apoptotic pathway in a rat model of Alzheimer's disease

Jun‑Shan Mu, Hang Lin, Jian‑Xin Ye, Min Lin, Xiao‑Ping Cui
Pages: 3862-3868
Published online on: 27 May 2015

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Article

Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells

Shi‑Min Yu, Dong‑Hui Hu, Jian‑Jun Zhang
Pages: 3869-3873
Published online on: 18 May 2015

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Article

Increase in osteoclastogenesis in an obese Otsuka Long-Evans Tokushima fatty rat model

Tomoyo Ootsuka, Atsuko Nakanishi, Ikuyo Tsukamoto
Pages: 3874-3880
Published online on: 21 May 2015

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Article

Interleukin-10 gene transfer into insulin-producing β cells protects against diabetes in non-obese diabetic mice

Aijing Xu, Wei Zhu, Tang Li, Xiuzhen Li, Jing Cheng, Cuiling Li, Peng Yi, Li Liu
Pages: 3881-3889
Published online on: 21 May 2015

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Article

Splicing factor 2/alternative splicing factor contributes to extracellular signal‑regulated kinase activation in hepatocellular carcinoma cells

Yawei Zhao, Ting Zhu, Xueying Zhang, Qingyang Wang, Jiyan Zhang, Wenbin Ji, Yuanfang Ma
Pages: 3890-3894
Published online on: 26 May 2015

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Article

Heparin inhibits lipopolysaccharide-induced inflammation via inducing caveolin-1 and activating the p38/mitogen-activated protein kinase pathway in murine peritoneal macrophages

Zhiyong Liu, Liang Wang, Zhe Dong, Jieyi Pan, Hong Zhu, Zhidan Zhang, Xiaochun Ma
Pages: 3895-3901
Published online on: 21 May 2015

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Article

CSN5 silencing reverses sorafenib resistance of human hepatocellular carcinoma HepG2 cells

Haibo Wang, Zhengyao Qian, Hui Zhao, Xibo Zhang, Shuqiang Che, Hongtao Zhang, Haitao Shang, Jianheng Bao, Chengfei Hao, Junjian Liu, Zhonglian Li
Pages: 3902-3908
Published online on: 29 May 2015

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Article

Efficacy of coenzyme Q10 in mitigating spinal cord injury‑induced osteoporosis

Xue‑Xue Zhang, Ke‑Jian Qian, Yong Zhang, Zhi‑Jian Wang, Yan‑Bo Yu, Xiao‑Jian Liu, Xin‑Tian Cao, Yun‑Hua Liao, Da‑Ying Zhang
Pages: 3909-3915
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Article

Podocalyxin promotes cisplatin chemoresistance in osteosarcoma cells through phosphatidylinositide 3‑kinase signaling

Zheng Huang, Yanke Huang, Hongtao He, Jiangdong Ni
Pages: 3916-3922
Published online on: 27 May 2015

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Article

MicroRNA-148a inhibits the proliferation and promotes the paclitaxel-induced apoptosis of ovarian cancer cells by targeting PDIA3 Retraction in /10.3892/mmr.2021.12294

Shuzhen Zhao, Zhengfang Wen, Shanshan Liu, Ying Liu, Xiaorui Li, Yanna Ge, Shaoru Li
Pages: 3923-3929
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Article

MicroRNA-522 reverses drug resistance of doxorubicin-induced HT29 colon cancer cell by targeting ABCB5

Ge Yang, Ou Jiang, Daiqiong Ling, Xiaoyue Jiang, Pingzong Yuan, Guang Zeng, Jing Zhu, Jie Tian, Yaguang Weng, Daoquan Wu
Pages: 3930-3936
Published online on: 04 June 2015

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Paeoniflorin ameliorates acute myocardial infarction of rats by inhibiting inflammation and inducible nitric oxide synthase signaling pathways

Chang Chen, Ping Du, Junjie Wang
Pages: 3937-3943
Published online on: 28 May 2015

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Article

MicroRNA-29a inhibits cell migration and invasion via targeting Roundabout homolog 1 in gastric cancer cells

Xueting Liu, Jun Cai, Yanjun Sun, Renhua Gong, Dengqun Sun, Xingguo Zhong, Shitao Jiang, Xinmiao He, Enwu Bao, Liusheng Yang, Yongxiang Li
Pages: 3944-3950
Published online on: 22 May 2015

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Article

MicroRNA-338-3p suppresses tumor growth of esophageal squamous cell carcinoma in vitro and in vivo Retraction in /10.3892/mmr.2021.12450

Xinyu Li, Zhihong Li, Guiyun Yang, Zhenxiang Pan
Pages: 3951-3957
Published online on: 22 May 2015

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Article

FHL1 inhibits the growth of tongue squamous cell carcinoma cells via G1/S cell cycle arrest

Wei Ren, Panfeng Lian, Long Cheng, Peiyun Du, Xin Guan, Hongyuan Wang, Lihua Ding, Zhenyang Gao, Xin Huang, Fengjun Xiao, Lisheng Wang, Xiaolin Bi, Qinong Ye, Enqun Wang
Pages: 3958-3964
Published online on: 25 May 2015

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Article

Expression and purification of the mGITR‑Fc fusion protein and its effect on CD4+ T cells and dendritic cells in vitro

Pei Shen, Zhaoliang Su, Ting Wang, Yanfang Liu, Yang Zhao, Qingzhen Han, Huaxi Xu, Shengjun Wang
Pages: 3965-3971
Published online on: 25 May 2015

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Article

Effects of small interfering RNA-mediated downregulation of the Krüppel-like factor 4 gene on collagen metabolism in human hepatic stellate cells

Tao Li, Lijuan Niu, Man Li, Ying Liu, Zhengrong Xu, Xia Gao, Dianwu Liu
Pages: 3972-3978
Published online on: 26 May 2015

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Article

Cyclin‑dependent kinase 5 regulates the proliferation, motility and invasiveness of lung cancer cells through its effects on cytoskeletal remodeling

Jun‑Li Liu, Run‑Xia Gu, Xiao‑Shu Zhou, Fang‑Zheng Zhou, Gang Wu
Pages: 3979-3985
Published online on: 27 May 2015

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Article

Protective effect of hydrogen‑rich medium against high glucose‑induced apoptosis of Schwann cells in vitro

Yang Yu, Xiaoye Ma, Tao Yang, Bo Li, Keliang Xie, Daquan Liu, Guolin Wang, Yonghao Yu
Pages: 3986-3992
Published online on: 02 June 2015

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Article

Effect of SCH442416 on glutamate uptake in retinal Müller cells at increased hydrostatic pressure

Yong Li, Xiaohong Liu, Shouyue Huang, Ping Huang, Yisheng Zhong
Pages: 3993-3998
Published online on: 03 June 2015

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Correction Open Access

[Corrigendum] Anti-inflammatory effects of Guolou Guizhi decoction in transient focal cerebral ischemic brains

Hai Xia Hu, Ru Hui Lin, Xiao Qin Zhu, Zuan Fang Li, Li Dian Chen
Pages: 3998-3998
Published online on: 04 June 2015

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Structure and function of Gab2 and its role in cancer (Review)

Chen‑Bo Ding, Wei‑Na Yu, Ji‑Hong Feng, Jun‑Min Luo
Pages: 4007-4014
Published online on: 17 June 2015

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Review

High-density lipoprotein synthesis and metabolism (Review)

Lingyan Zhou, Congcong Li, Ling Gao, Aihong Wang
Pages: 4015-4021
Published online on: 15 June 2015

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Review

Diagnostic and therapeutic research on ultrasound microbubble/nanobubble contrast agents (Review)

Jing Ma, Chang Song Xu, Feng Gao, Ming Chen, Fan Li, Lian Fang Du
Pages: 4022-4028
Published online on: 16 June 2015

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Expression of podoplanin and vimentin is correlated with prognosis in esophageal squamous cell carcinoma

Makiko Tanaka, Hiroshi Kijima, Hideo Shimada, Hiroyasu Makuuchi, Soji Ozawa, Sadaki Inokuchi
Pages: 4029-4036
Published online on: 19 June 2015

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A single nucleotide polymorphism in primary‑microRNA‑146a reduces the expression of mature microRNA‑146a in patients with Alzheimer's disease and is associated with the pathogenesis of Alzheimer's disease

Bin Zhang, Aihong Wang, Cuiping Xia, Qunfeng Lin, Chunfu Chen
Pages: 4037-4042
Published online on: 22 June 2015

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Mycophenolate mofetil ameliorates diabetic nephropathy through epithelial mesenchymal transition in rats

Xiaoyan Xiao, Jie Wang, Xiangdi Chang, Junhui Zhen, Gengyin Zhou, Zhao Hu
Pages: 4043-4050
Published online on: 15 June 2015

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Antiproliferative effect of dexamethasone in the MCF-7 breast cancer cell line

Frederic Buxant, Nadège Kindt, Guy Laurent, Jean‑Christophe Noël, Sven Saussez
Pages: 4051-4054
Published online on: 12 June 2015

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Protective effects of tanshinone ⅡA on endothelial progenitor cells injured by tumor necrosis factor‑α

Xing‑Xiang Wang, Jin‑Xiu Yang, Yan‑Yun Pan, Ye‑Fei Zhang
Pages: 4055-4062
Published online on: 22 June 2015

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Lentivirus transduced interleukin‑1 receptor antagonist gene expression in murine bone marrow‑derived mesenchymal stem cells in vitro

Tao He, Guanghao Chi, Bo Tian, Tingting Tang, Kerong Dai
Pages: 4063-4070
Published online on: 26 June 2015

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Expression of HAX-1 in colorectal cancer and its role in cancer cell growth

Xiaolan Li, Jianwu Jiang, Rui Yang, Xiangshang Xu, Fayong Hu, Anding Liu, Deding Tao, Yan Leng, Junbo Hu, Jianping Gong, Xuelai Luo
Pages: 4071-4078
Published online on: 11 June 2015

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Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D‑Ala2, D‑Leu5)‑enkephalin through inhibition of the MKK7‑JNK signaling pathway Retraction in /10.3892/mmr.2024.13403

Zhenran Wang, Bo Tang, Fang Tang, Yang Li, Guangyu Zhang, Li Zhong, Chencheng Dong, Songqing He
Pages: 4079-4088
Published online on: 24 June 2015

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Lumican overexpression exacerbates lipopolysaccharide-induced renal injury in mice

Xiao‑Mei Lu, Ling Ma, Yu‑Nan Jin, Yan‑Qiu Yu
Pages: 4089-4094
Published online on: 16 June 2015

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Hepatoprotective effect of juglone on dimethylnitrosamine‑induced liver fibrosis and its effect on hepatic antioxidant defence and the expression levels of α‑SMA and collagen III

De‑Jiang Zhou, Dong Mu, Ming‑De Jiang, Shu‑Mei Zheng, Yong Zhang, Sheng He, Min Weng, Wei‑Zheng Zeng
Pages: 4095-4102
Published online on: 24 June 2015

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Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model

Tao Yin, Sisi He, Guobo Shen, Tinghong Ye, Fuchun Guo, Yongsheng Wang
Pages: 4103-4108
Published online on: 22 June 2015

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Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis

Xiaowen Cheng, Xiaobian Wang, Yufeng Wan, Qing Zhou, Huaqing Zhu, Yuan Wang
Pages: 4109-4116
Published online on: 22 June 2015

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Investigation of the structure of anti‑human seminal plasma protein single‑chain antibody and its association with linker peptide length

Xin Jiang, Jun Zhai, Dongkui Song, Qingshan Qu, Ming Li, Li Xing, Shuzhai Miao
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Published online on: 22 June 2015

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Chitosan as an adjuvant for a Helicobacter pylori therapeutic vaccine

Yanfeng Gong, Liming Tao, Fucai Wang, Wei Liu, Lei Jing, Dongsheng Liu, Sijun Hu, Yong Xie, Nanjin Zhou
Pages: 4123-4132
Published online on: 17 June 2015

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Genomic expression profiling and bioinformatics analysis of pancreatic cancer

Dong‑Yan Han, Da Fu, Hao Xi, Qian‑Yu Li, Li‑Jin Feng, Wei Zhang, Guo Ji, Jia‑Cheng Xiao, Qing Wei
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Published online on: 11 June 2015

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15-Hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes

Hak‑Jae Kim, Sora Lee, Haw‑Yong Lee, Hansol Won, Sung‑Hae Chang, Seong‑Su Nah
Pages: 4141-4148
Published online on: 15 June 2015

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Analysis of polyunsaturated fatty acids and the omega-6 inflammatory pathway in hepatic ischemia/re-perfusion injury

Ebru Kirac, Filiz Özcan, Hazal Tuzcu, Gulsum O. Elpek, Mutay Aslan
Pages: 4149-4156
Published online on: 11 June 2015

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Overexpression of Indian hedgehog partially rescues short stature homeobox 2-overexpression‑associated congenital dysplasia of the temporomandibular joint in mice

Xihai Li, Wenna Liang, Hongzhi Ye, Xiaping Weng, Fayuan Liu, Pingdong Lin, Xianxiang Liu
Pages: 4157-4164
Published online on: 18 June 2015

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Neutrophil elastase and its therapeutic effect on leukemia cells

Kai‑Ling Jiang, Peng‑Peng Ma, Xiao‑Qun Yang, Liang Zhong, Hui Wang, Xin‑Yu Zhu, Bei‑Zhong Liu
Pages: 4165-4172
Published online on: 17 June 2015

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Ionizing radiation-induced microRNA expression changes in cultured RGC-5 cells

Kaijun Wang, Meijuan Zhu, Panpan Ye, Guodi Chen, Wei Wang, Min Chen
Pages: 4173-4178
Published online on: 16 June 2015

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Coagulation defects associated with massive blood transfusion: A large multicenter study

Jiang‑Cun Yang, Yang Sun, Cui‑Xiang Xu, Qian‑Li Dang, Ling Li, Yong‑Gang Xu, Yao‑Jun Song, Hong Yan
Pages: 4179-4186
Published online on: 22 June 2015

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Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway

Li Huang, Yong Kong, Jing Wang, Jie Sun, Qin Shi, Yu‑Hua Qiu
Pages: 4187-4195
Published online on: 18 June 2015

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Luteolin exerts an anticancer effect on NCI-H460 human non-small cell lung cancer cells through the induction of Sirt1-mediated apoptosis

Liping Ma, Hongjun Peng, Kunsheng Li, Runrun Zhao, Li Li, Yilong Yu, Xiaoming Wang, Zhifeng Han
Pages: 4196-4202
Published online on: 18 June 2015

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Significance of genetic variants in DLC1 and their association with hepatocellular carcinoma

Cheng‑Rong Xie, Hong‑Guang Sun, Yu Sun, Wen‑Xiu Zhao, Sheng Zhang, Xiao‑Min Wang, Zhen‑Yu Yin
Pages: 4203-4209
Published online on: 22 June 2015

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Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E‑/‑ mice by activating autophagy

Jia Wang, Jie Wu, Hong Wu, Xingzhen Liu, Yingjian Chen, Jianying Wu, Chengjin Hu, Dajin Zou
Pages: 4210-4218
Published online on: 16 June 2015

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Recombinant LH supplementation during IVF cycles with a GnRH-antagonist in estimated poor responders: A cross-matched pilot investigation of the optimal daily dose and timing

Salvatore Gizzo, Alessandra Andrisani, Marco Noventa, Serena Manfè, Alessandra Oliva, Michele Gangemi, Giovanni Battista Nardelli, Guido Ambrosini
Pages: 4219-4229
Published online on: 09 June 2015

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Role of bone morphogenetic protein-2 in osteogenic differentiation of mesenchymal stem cells

Jian Sun, Jieyun Li, Chichi Li, Youcheng Yu
Pages: 4230-4237
Published online on: 18 June 2015

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Alendronate, a double-edged sword acting in the mevalonate pathway

Paola Maura Tricarico, Martina Girardelli, Giulio Kleiner, Alessandra Knowles, Erica Valencic, Sergio Crovella, Annalisa Marcuzzi
Pages: 4238-4242
Published online on: 18 June 2015

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Urinary N telopeptide levels in predicting the anti-nociceptive responses of zoledronic acid and paclitaxel in a rat model of bone metastases

Qi Gui, Chengcheng Xu, Dapeng Li, Liang Zhuang, Shu Xia, Shiying Yu
Pages: 4243-4249
Published online on: 17 June 2015

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Integrated analysis of gene expression and DNA methylation changes induced by hepatocyte growth factor in human hepatocytes

Cheng‑Rong Xie, Hongguang Sun, Fu‑Qiang Wang, Zhao Li, Yi‑Rui Yin, Qin‑Liang Fang, Yu Sun, Wen‑Xiu Zhao, Sheng Zhang, Wen‑Xing Zhao, Xiao‑Min Wang, Zhen‑Yu Yin
Pages: 4250-4258
Published online on: 22 June 2015

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Overexpression of δ-catenin is associated with a malignant phenotype and poor prognosis in colorectal cancer

Hong Zhang, Shun‑Dong Dai, Shu‑Li Liu, Fang‑Yuan Zhang, Chao‑Liu Dai
Pages: 4259-4265
Published online on: 11 June 2015

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Gene expression profiling analysis of osteosarcoma cell lines

Lu Sun, Jie Li, Bing Yan
Pages: 4266-4272
Published online on: 18 June 2015

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Yifei Xuanfei Jiangzhuo formula, a Chinese herbal decoction, improves memory impairment through inhibiting apoptosis and enhancing PKA/CREB signal transduction in rats with cerebral ischemia/reperfusion

Lin Wu, Qing-Shan Zhao, Tian-Wei Li, Hai-Yuan Li, Qing‑Bi Wang, Xin-Ya Bi, Xin-Kun Cai, Nong Tang
Pages: 4273-4283
Published online on: 18 June 2015

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Microarray and ChIP‑seq data analysis revealed changes in p53-mediated transcriptional regulation in Nutlin-3-treated U2OS cells

Song Zhao, Feng Niu, Chang‑Yan Xu, Long Ye, Gui‑Bin Bi, Lin Chen, Ping Gong, Gang Tian, Tian‑Hong Nie
Pages: 4284-4290
Published online on: 15 June 2015

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Vorinostat protects against calcium oxalate-induced kidney injury in mice Corrigendum in /10.3892/mmr.2020.11782

Li Wang, Wei Chen, Zhongjiang Peng, Changcheng Liu, Caihong Zhang, Zhiyong Guo
Pages: 4291-4297
Published online on: 19 June 2015

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Brachyury: A sensitive marker, but not a prognostic factor, for skull base chordomas

Ke Wang, Kaibing Tian, Liang Wang, Zhen Wu, Cong Ren, Shuyu Hao, Jie Feng, Junhua Li, Hong Wan, Guijun Jia, Liwei Zhang, Junting Zhang
Pages: 4298-4304
Published online on: 22 June 2015

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Article Open Access

Effects of GnRH agonists on the expression of developmental follicular anti‑mullerian hormone in varying follicular stages in cyclic mice in vivo

Jiliang Huang, Xiaoyan Wang, Zhiling Li, Ruowu Ma, Wanfen Xiao
Pages: 4305-4313
Published online on: 24 June 2015

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Article

Involvement of glutathione and glutathione metabolizing enzymes in human colorectal cancer cell lines and tissues

Areum Daseul Kim, Rui Zhang, Xia Han, Kyoung Ah Kang, Mei Jing Piao, Young Hee Maeng, Weon Young Chang, Jin Won Hyun
Pages: 4314-4319
Published online on: 09 June 2015

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Article

Characteristics of human umbilical cord mesenchymal stem cells during ex vivo expansion

Shengying Li, Yuxia Wang, Liping Guan, Mingli Ji
Pages: 4320-4325
Published online on: 25 June 2015

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Article

Screening of targeted genes in extrahepatic bile ducts of mice with experimental biliary atresia

Zhen You, Jing Wen, Liping Cheng, Hui Ye, Bei Li
Pages: 4326-4331
Published online on: 09 June 2015

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Article

CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts

Kang Li, Zeng Dan, Yuqiang Nie, Xuejun Hu, Luobu Gesang, Zhaxi Bianba, Yongge Ze, Cuomu Ciren
Pages: 4332-4339
Published online on: 12 June 2015

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Article

Blockade of vascular endothelial growth factor-A/receptor 2 exhibits a protective effect on angiotensin-II stimulated podocytes

Xiangchun Liu, Hong Zhang, Qun Wang, Kezhou Yu, Rong Wang, Jing Sun
Pages: 4340-4345
Published online on: 11 June 2015

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Article

IRX2-mediated upregulation of MMP-9 and VEGF in a PI3K/AKT-dependent manner

Tielong Liu, Weiwei Zhou, Bing Cai, Jianjun Chu, Guodong Shi, Honglin Teng, Jian Xu, Jianru Xiao, Yan Wang
Pages: 4346-4351
Published online on: 11 June 2015

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Article

Abnormal Wnt signaling and overexpression of ABCG2 contributes to drug efflux properties of side population cells in nasopharyngeal carcinoma

Guo-Fang Guan, De-Jun Zhang, Ying Zheng, Lian-Ji Wen, Duo-Jiao Yu, Yan-Qing Lu, Yan Zhao
Pages: 4352-4357
Published online on: 16 June 2015

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Article

Knockdown of PKM2 induces apoptosis and autophagy in human A549 alveolar adenocarcinoma cells

Beibei Chu, Jiang Wang, Yueying Wang, Guoyu Yang
Pages: 4358-4363
Published online on: 16 June 2015

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Article

Clinical investigation of TROP-2 as an independent biomarker and potential therapeutic target in colon cancer

Peng Zhao, Hai‑Zheng Yu, Jian‑Hui Cai
Pages: 4364-4369
Published online on: 08 June 2015

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Case Report

A case of lung adenocarcinoma with a concurrent EGFR mutation and ALK rearrangement: A case report and literature review

Chun‑Wei Xu, Xue‑Ying Cai, Yuan Shao, Yang Li, Ming‑Wei Shi, Li‑Ying Zhang, Lin Wang, Yu‑Ping Zhang, Lu‑Ping Wang, Yu‑Wang Tian
Pages: 4370-4375
Published online on: 26 June 2015

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Article

Comparative study of IDH1 mutations in gliomas by high resolution melting analysis, immunohistochemistry and direct DNA sequencing

Juan Li, Haiyan Zhang, Li Wang, Chuanhong Yang, Huangwen Lai, Wei Zhang, Xiaodong Chen, Jie Wang
Pages: 4376-4381
Published online on: 23 June 2015

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Article

Protective effect of pyrroloquinoline quinine on ultraviolet A irradiation‑induced human dermal fibroblast senescence in vitro proceeds via the anti‑apoptotic sirtuin 1/nuclear factor‑derived erythroid 2‑related factor 2/heme oxygenase 1 pathway

Chunli Zhang, Chuanjun Wen, Jinde Lin, Gan Shen
Pages: 4382-4388
Published online on: 24 June 2015

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Article

Targeted knockout of TNF‑α by injection of lentivirus‑mediated siRNA into the subacromial bursa for the treatment of subacromial bursitis in rats

Yi Wang, Quan Li, Xianzhao Wei, Jie Xu, Qi Chen, Shuang Song, Zhe Lu, Zimin Wang
Pages: 4389-4395
Published online on: 23 June 2015

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Article

Anti-tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC-803 proliferation via phospho-extracellular signal-regulated kinase-, Src-, c-Jun N-terminal kinase- and phosphoinositide 3-kinase-associated pathways

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Pages: 4396-4402
Published online on: 11 June 2015

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Article

microRNA-513c suppresses the proliferation of human glioblastoma cells by repressing low-density lipoprotein receptor-related protein 6

Jiajun Xu, Tao Sun, Xuebing Hu
Pages: 4403-4409
Published online on: 11 June 2015

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Article

Estradiol suppresses neuronal firing activity and c-Fos expression in the lateral habenula

Chun‑Ying Li, Mei‑Ying Song, Min Huang, Ji‑Cheng Li, Jin‑Yu Xiao, Hua Zhao
Pages: 4410-4414
Published online on: 16 June 2015

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Article

Rhein inhibits lipopolysaccharide-induced intestinal injury during sepsis by blocking the toll-like receptor 4 nuclear factor-κB pathway

Ke Zhang, Xian Fa Jiao, Jin Xiu Li, Xiao Wen Wang
Pages: 4415-4421
Published online on: 12 June 2015

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Article

Protective effect of vitamin E on methyl methanesulfonate-induced teratozoospermia in adult Sprague-Dawley rats

Zhian Tang, Weiliang Ding, Lun Wang, Wenchu Jiang, Quanxiang Zhang, Hong Chen, Hongnan Zou, Yongkang Dong, Jianwei Shao, Tieliang Ma
Pages: 4422-4426
Published online on: 11 June 2015

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Article

Emodin inhibits the proliferation of PC3 prostate cancer cells in vitro via the Notch signaling pathway

Gang Deng, Xiang Ju, Qi Meng, Zhi‑Jian Yu, Li‑Bin Ma
Pages: 4427-4433
Published online on: 12 June 2015

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Article

Genetic variation in the coagulation factor V gene and risk of femoral head osteonecrosis

Tae‑Ho Kim, Seung‑Hoon Baek, Jeong Ok Lim, Sang‑Han Lee, Shin‑Yoon Kim
Pages: 4434-4440
Published online on: 25 June 2015

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Article

Wake-promoting actions of median nerve stimulation in TBI-induced coma: An investigation of orexin-A and orexin receptor 1 in the hypothalamic region

Ying‑Jun Zhong, Zhen Feng, Liang Wang, Tian‑Qi Wei
Pages: 4441-4447
Published online on: 08 June 2015

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Article

Cadmium-induced autophagy is mediated by oxidative signaling in PC-12 cells and is associated with cytoprotection

Qi-Wen Wang, Yi Wang, Tao Wang, Kang-Bao Zhang, Yan Yuan, Jian‑Chun Bian, Xue-Zhong Liu, Jian-Hong Gu, Jia-Qiao Zhu, Zong-Ping Liu
Pages: 4448-4454
Published online on: 11 June 2015

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Article

Effects of salinomycin and CGP37157 on head and neck squamous cell carcinoma cell lines in vitro

Agmal Scherzed, Stephan Hackenberg, Katrin Froelich, Kristen Rak, Christian Ginzkey, Rudolf Hagen, Philipp Schendzielorz, Norbert Kleinsasser
Pages: 4455-4461
Published online on: 22 June 2015

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Article

Synergistic effect of HMGB1 knockdown and cordycepin in the K562 human chronic myeloid leukemia cell line

Xi Chen, Ying Wang, Juan Liu, Ping Xu, Xiao‑Min Zhang, Yao‑Yao Tian, Yan‑Ming Xue, Xin‑Yu Gao, Yao Liu, Jing‑Hua Wang
Pages: 4462-4468
Published online on: 15 June 2015

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Article

Correlation between thyroglobulin gene polymorphisms and autoimmune thyroid disease

Li‑Qiang Wang, Tian‑Yun Wang, Qiu‑Li Sun, Yong‑Qiang Qie
Pages: 4469-4475
Published online on: 22 June 2015

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Article

Soy isoflavones protect against H2O2-induced injury in human umbilical vein endothelial cells

Lianhai Jin, Xingyu Zhao, Yingxin Qin, Wenhe Zhu, Wei Zhang, Anheng Liu, Zhengli Luo
Pages: 4476-4482
Published online on: 17 June 2015

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Article

Conformational changes in inter‑α‑trypsin inhibitor heavy chain 4 activate its tumor‑specific activity in mice with B16 melanoma

Natalya G. Kormosh, Tatyana V. Davidova, Vladimir N. Kopyltsov, Marina V. Serebryakova, Aigul O. Kabieva, Konstantin E. Voyushin, Suriya M. Sitdikova, Berick S. Amandzholov, Michail V. Kiselevskii, Fedor V. Donenko
Pages: 4483-4493
Published online on: 18 June 2015

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Article

Activation of the endoplasmic reticulum stress pathway involving CHOP in the lungs of rats with hyperoxia‑induced bronchopulmonary dysplasia

Hong‑Yan Lu, Jie Zhang, Qiu‑Xia Wang, Wei Tang, Lu‑Jie Zhang
Pages: 4494-4500
Published online on: 22 June 2015

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Article

Effects of fucoidan on insulin stimulation and pancreatic protection via the cAMP signaling pathway in vivo and in vitro

Xiaoming Jiang, Jinfeng Yu, Zhi Ma, Hong Zhang, Fengjie Xie
Pages: 4501-4507
Published online on: 23 June 2015

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Article

Triptolide suppresses proliferation, hypoxia-inducible factor-1α and c-Myc expression in pancreatic cancer cells

Xiaoling Ding, Xiaorong Zhou, Bo Jiang, Qun Zhao, Guoxiong Zhou
Pages: 4508-4513
Published online on: 18 June 2015

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Article

Quantitative analysis of the mRNA expression levels of BCL2 and BAX genes in human osteoarthritis and normal articular cartilage: An investigation into their differential expression

Georgios I. Karaliotas, Konstantinos Mavridis, Andreas Scorilas, George C. Babis
Pages: 4514-4521
Published online on: 16 June 2015

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Article

Expression of brain‑specific angiogenesis inhibitor‑1 and association with p53, microvessel density and vascular endothelial growth factor in the tissue of human bladder transitional cell carcinoma

Dawei Tian, Hailong Hu, Yan Sun, Yang Tang, Mingde Lei, Liwei Liu, Ruifa Han, Changli Wu
Pages: 4522-4529
Published online on: 23 June 2015

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Article

Downregulation of Meg3 enhances cisplatin resistance of lung cancer cells through activation of the WNT/β-catenin signaling pathway

Yang Xia, Zhicheng He, Bin Liu, Pengli Wang, Yijiang Chen
Pages: 4530-4537
Published online on: 08 June 2015

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Article

Zingiber mioga (Thunb.) Roscoe attenuates allergic asthma induced by ovalbumin challenge

Na‑Rae Shin, In‑Sik Shin, Chan‑Mi Jeon, Ju‑Mi Hong, Ok‑Kyoung Kwon, Hui‑Seong Kim, Sei‑Ryang Oh, Kyu‑Woung Hahn, Kyung‑Seop Ahn
Pages: 4538-4545
Published online on: 11 June 2015

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Article

NADPH oxidase-derived production of reactive oxygen species is involved in learning and memory impairments in 16-month-old female rats

Hongwei Kan, Wen Hu, Yuchan Wang, Wangyang Wu, Yanyan Yin, Yan Liang, Chunyan Wang, Dake Huang, Weizu Li
Pages: 4546-4553
Published online on: 08 June 2015

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Article

MicroRNA-144 acts as a tumor suppressor by targeting Rho-associated coiled-coil containing protein kinase 1 in osteosarcoma cells Retraction in /10.3892/mmr.2021.12344

Jianjun Huang, Ying Shi, Hui Li, Meisongzhu Yang, Guohong Liu
Pages: 4554-4559
Published online on: 16 June 2015

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Article

Study of the association of the T869C polymorphism of the transforming growth factor-β1 gene with polycystic ovary syndrome

Jung‑Hyun Park, Lan Li, Kwang‑Hyun Baek
Pages: 4560-4565
Published online on: 08 June 2015

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Article

Purine analogue ENERGI-F706 induces apoptosis of 786-O renal carcinoma cells via 5'-adenosine monophosphate-activated protein kinase activation

Chao‑Yu Hsu, Chun‑Hsiang Lin, Jiun‑Tsai Lin, Yi‑Fang Cheng, Han‑Min Chen, Shao‑Hsuan Kao
Pages: 4566-4571
Published online on: 11 June 2015

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Article

Berberine induces apoptosis by suppressing the arachidonic acid metabolic pathway in hepatocellular carcinoma

Jing Li, Ou Li, Mujie Kan, Ming Zhang, Dan Shao, Yue Pan, Huilin Zheng, Xuewen Zhang, Li Chen, Songyan Liu
Pages: 4572-4577
Published online on: 12 June 2015

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Article

Diterpenoid B derived from Plectranthus excisus inhibits the melanoma cell cycle in the B16 melanoma cell line

Ya‑Nan Liu, Jun‑Lian Gu, Meng‑Shi Ma, Hua Guo, Long Liu, Li‑Rong Guo, Yue Wang, Yang Li
Pages: 4578-4583
Published online on: 23 June 2015

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Article

Characteristics of regulatory B10 cells in patients with rheumatoid arthritis with different disease status

Zhaohui Zheng, Xueyi Li, Xiaoyan Li, Jin Ding, Yuan Feng, Jinlin Miao, Xing Luo, Zhenbiao Wu, Ping Zhu
Pages: 4584-4591
Published online on: 12 June 2015

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Article

Osthole suppresses the proliferation and accelerates the apoptosis of human glioma cells via the upregulation of microRNA-16 and downregulation of MMP-9

Kai Lin, Zhiyu Gao, Bin Shang, Shaohua Sui, Qiang Fu
Pages: 4592-4597
Published online on: 15 June 2015

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Article

Chitosan prevents adhesion during rabbit flexor tendon repair via the sirtuin 1 signaling pathway

Qiang Chen, Hui Lu, Hu Yang
Pages: 4598-4603
Published online on: 30 June 2015

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Article

Tanshinone IIA exerts antitumor activity against vestibular schwannoma cells by inhibiting the expression of hypoxia-inducible factor-1α

Ju Yeon Kim, Jae‑Jun Song, Byoung‑Mog Kwon, Jong Dae Lee
Pages: 4604-4609
Published online on: 15 June 2015

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Article

Novel real‑time cell analysis platform for the dynamic monitoring of ionizing radiation effects on human tumor cell lines and primary fibroblasts

Imola Mán, Gábor J. Szebeni, Imola Plangár, Emilia R. Szabó, Tünde Tőkés, Zoltán Szabó, Zoltán Nagy, Gábor Fekete, Roberta Fajka‑Boja, László G. Puskás, Katalin Hideghéty, László Hackler Jr.
Pages: 4610-4619
Published online on: 26 June 2015

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Article

Zoledronic acid inhibits the pentose phosphate pathway through attenuating the Ras‑TAp73‑G6PD axis in bladder cancer cells

Xiaolin Wang, Guang Wu, Guangxin Cao, Lei Yang, Haifei Xu, Jian Huang, Jianquan Hou
Pages: 4620-4625
Published online on: 24 June 2015

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Article

Association study of C936T polymorphism of the VEGF gene and the C242T polymorphism of the p22phox gene with diabetes mellitus type 2 and distal diabetic polyneuropathy

Melissa Mottin Ghisleni, Vanderlei Biolchi, Bruna Cristina Jordon, Claudete Rempel, Júlia Pasqualini Genro, Adriane Pozzobon
Pages: 4626-4633
Published online on: 23 June 2015

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Article

LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt/β‑catenin signaling pathway

Zhuang Hu, Lingling Xie
Pages: 4634-4639
Published online on: 25 June 2015

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Article

Thuja orientalis reduces airway inflammation in ovalbumin-induced allergic asthma

In‑Sik Shin, Na‑Rae Shin, Chan‑Mi Jeon, Ok‑Kyoung Kwon, Ju‑Mi Hong, Hui‑Seong Kim, Sei‑Ryang Oh, Kyung‑Seop Ahn
Pages: 4640-4646
Published online on: 11 June 2015

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Article

MicroRNA-802 suppresses breast cancer proliferation through downregulation of FoxM1

Feng Yuan, Wei Wang
Pages: 4647-4651
Published online on: 12 June 2015

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Article

MicroRNA-205 regulates ubiquitin specific peptidase 7 protein expression in hepatocellular carcinoma cells

Liang Zhu, Rong Liu, Wei Zhang, Sheng Qian, Jian‑Hua Wang
Pages: 4652-4656
Published online on: 25 June 2015

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Article

Nanoparticle-mediated RNA interference of angiotensinogen decreases blood pressure and improves myocardial remodeling in spontaneously hypertensive rats

Li‑Fen Yuan, Jing Sheng, Ping Lu, Yu‑Qiang Wang, Tuo Jin, Qin Du
Pages: 4657-4663
Published online on: 11 June 2015

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Article

Adipose-derived stem cells improve the viability of nucleus pulposus cells in degenerated intervertebral discs

Keran Song, Tao Gu, Feng Shuang, Jiaguang Tang, Dongfeng Ren, Jiang Qin, Shuxun Hou
Pages: 4664-4668
Published online on: 08 June 2015

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Article

Engineering and characterization of a symbiotic selection-marker-free vector-host system for therapeutic plasmid production

Xinchang Shi, Junzhi Wang
Pages: 4669-4677
Published online on: 17 June 2015

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Article

Targeted sequencing of cancer-associated genes in hepatocellular carcinoma using next generation sequencing

Jianguo Lu, Jikai Yin, Rui Dong, Tao Yang, Lijuan Yuan, Li Zang, Cheng Xu, Bo Peng, Jiangman Zhao, Xilin Du
Pages: 4678-4682
Published online on: 17 June 2015

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Article

Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies

Yi Li, Gui‑Ming Xiang, Lin‑Lin Liu, Chang Liu, Fei Liu, Dong‑Neng Jiang, Xiao‑Yun Pu
Pages: 4683-4691
Published online on: 11 June 2015

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Article

Relative levels of let‑7a, miR‑17, miR‑27b, miR‑125a, miR‑125b and miR‑206 as potential molecular markers to evaluate grade, receptor status and molecular type in breast cancer

Tomasz P. Lehmann, Konstanty Korski, Robert Gryczka, Mathew Ibbs, Anna Thieleman, Sylwia Grodecka‑Gazdecka, Paweł P. Jagodziński
Pages: 4692-4702
Published online on: 26 June 2015

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Article

Adiponectin affects vascular smooth muscle cell proliferation and apoptosis through modulation of the mitofusin-2-mediated Ras-Raf-Erk1/2 signaling pathway

Wenbo Zhang, Chang Shu, Quanming Li, Ming Li, Xin Li
Pages: 4703-4707
Published online on: 08 June 2015

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Article

Osteopontin induces vascular endothelial growth factor expression in articular cartilage through PI3K/AKT and ERK1/2 signaling

Jun Xu, Yu Yi, Lin Li, Weiguo Zhang, Jianhua Wang
Pages: 4708-4712
Published online on: 22 June 2015

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Article

Downregulation of the expression of HDGF attenuates malignant biological behaviors of hilar cholangiocarcinoma cells

Yanfeng Liu, Jingxian Sun, Guangyun Yang, Zhaojian Liu, Sen Guo, Rui Zhao, Kesen Xu, Xiaopeng Wu, Zhaoyang Zhang
Pages: 4713-4719
Published online on: 12 June 2015

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Article

Lipoteichoic acid upregulates NF-κB and proinflammatory cytokines by modulating β-catenin in bronchial epithelial cells

Jaewoong Jang, Wonyong Kim, Kijeong Kim, Sang-In Chung, Yae Jie Shim, Seok-Min Kim, Yoosik Yoon
Pages: 4720-4726
Published online on: 19 June 2015

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Article

Epigenetic modulation of Wnt signaling contributes to neuropathic pain in rats

Wei Feng, Ruynag Teng, Yang Zhao, Jie Gao, Haichen Chu
Pages: 4727-4733
Published online on: 22 June 2015

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Article

DJ-1 upregulates anti-oxidant enzymes and attenuates hypoxia/re-oxygenation-induced oxidative stress by activation of the nuclear factor erythroid 2-like 2 signaling pathway

Yu-Feng Yan, Wen-Jie Yang, Qiang Xu, He-Ping Chen, Xiao-Shan Huang, Ling-Yu Qiu, Zhang-Ping Liao, Qi-Ren Huang
Pages: 4734-4742
Published online on: 17 June 2015

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Article

Arginase inhibition protects against hypoxia‑induced pulmonary arterial hypertension

Wenjin Jiang, Bolin Sun, Xuepeng Song, Yanbo Zheng, Ligang Wang, Tao Wang, Sheng Liu
Pages: 4743-4749
Published online on: 24 June 2015

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Article

Synergistic apoptosis-inducing effect of aspirin and isosorbide mononitrate on human colon cancer cells

Xiaodong Wang, Yuwen Diao, Yu Liu, Ningning Gao, Dong Gao, Yanyan Wan, Jingjing Zhong, Guangyi Jin
Pages: 4750-4758
Published online on: 18 June 2015

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Article

Naringin promotes differentiation of bone marrow stem cells into osteoblasts by upregulating the expression levels of microRNA‑20a and downregulating the expression levels of PPARγ

Jifeng Fan, Jie Li, Qinbo Fan
Pages: 4759-4765
Published online on: 24 June 2015

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Article

Collagen and prostaglandin E2 regulate aromatase expression through the PI3K/AKT/IKK and the MAP kinase pathways in adipose stromal cells

Ting Tan, Lie Wang, Bing Wang
Pages: 4766-4772
Published online on: 09 June 2015

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Article

Quantitative analysis and anti-inflammatory effects of Gleditsia sinensis thorns in RAW 264.7 macrophages and HaCaT keratinocytes

Chang‑Seob Seo, Hye‑Sun Lim, Hyekyung Ha, Seong Eun Jin, Hyeun‑Kyoo Shin
Pages: 4773-4781
Published online on: 16 June 2015

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Article

Corosolic acid enhances 5‑fluorouracil‑induced apoptosis against SNU‑620 human gastric carcinoma cells by inhibition of mammalian target of rapamycin

Hyun Su Lee, Jun Beom Park, Myung Sun Lee, Eun Young Cha, Ji Yeon Kim, Ji Young Sul
Pages: 4782-4788
Published online on: 22 June 2015

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Article

Curcumin inhibits human cytomegalovirus by downregulating heat shock protein 90

Yali Lv, Lili Gong, Zihui Wang, Feifei Han, He Liu, Xuechun Lu, Lihong Liu
Pages: 4789-4793
Published online on: 22 June 2015

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Correction Open Access

[Erratum] HER 2/neu protein expression in gastric cancer is associated with poor survival

S. D. Xie, C. Y. Xu, J. G. Shen, Z. N. Jiang, J. Y. Shen, L. B. Wang
Pages: 4794-4794
Published online on: 18 June 2015

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Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
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Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Published online on: 10 November 2025

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Article Number: 33
Published online on: 10 November 2025

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Article Number: 32
Published online on: 06 November 2025

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Published online on: 03 November 2025

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Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Published online on: 03 November 2025

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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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Published online on: 03 November 2025

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Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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Published online on: 31 October 2025

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Published online on: 29 October 2025

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Article Number: 20
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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

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Published online on: 29 October 2025

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Article Number: 18
Published online on: 29 October 2025

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Article Number: 17
Published online on: 29 October 2025

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Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
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Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

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Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Published online on: 23 October 2025

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Article Number: 10
Published online on: 22 October 2025

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Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

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Article Number: 7
Published online on: 15 October 2025

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Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

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Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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