|
1
|
Salehi M, Aulinger BA and D'Alessio DA:
Targeting beta-cell mass in type 2 diabetes: promise and
limitations of new drugs based on incretins. Endocr Rev.
29:367–379. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ritzel RA: Therapeutic approaches based on
beta-cell mass preservation and/or regeneration. Front Biosci
(Landmark Ed). 14:1835–1850. 2009. View
Article : Google Scholar
|
|
3
|
Berlie H, Hurren KM and Pinelli NR:
Glucagon-like peptide-1 receptor agonists as add-on therapy to
basal insulin in patients with type 2 diabetes: a systematic
review. Diabetes Metab Syndr Obes. 5:165–174. 2012.PubMed/NCBI
|
|
4
|
Grieve DJ, Cassidy RS and Green BD:
Emerging cardiovascular actions of the incretin hormone
glucagon-like peptide-1: potential therapeutic benefits beyond
glycaemic control? Br J Pharmacol. 157:1340–1351. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Laybutt DR, Preston AM, Akerfeldt MC, et
al: Endoplasmic reticulum stress contributes to beta cell apoptosis
in type 2 diabetes. Diabetologia. 50:752–763. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Ogata M, Hino S, Saito A, et al: Autophagy
is activated for cell survival after endoplasmic reticulum stress.
Mol Cell Biol. 26:9220–9231. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Choi SE, Lee SM, Lee YJ, et al: Protective
role of autophagy in palmitate-induced INS-1 beta-cell death.
Endocrinology. 150:126–134. 2009. View Article : Google Scholar
|
|
8
|
Marchetti P and Masini M: Autophagy and
the pancreatic beta-cell in human type 2 diabetes. Autophagy.
5:1055–1056. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Hartley T, Brumell J and Volchuk A:
Emerging roles for the ubiquitin-proteasome system and autophagy in
pancreatic beta-cells. Am J Physiol Endocrinol Metab. 296:E1–E10.
2009. View Article : Google Scholar
|
|
10
|
Masini M, et al: Autophagy in human type 2
diabetes pancreatic beta cells. Diabetologia. 52:1083–1086. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ichimura Y, Kumanomidou T, Sou YS, et al:
Structural basis for sorting mechanism of p62 in selective
autophagy. J Biol Chem. 283:22847–22857. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Marsh BJ, Soden C, Alarcon C, et al:
Regulated autophagy controls hormone content in secretory-deficient
pancreatic endocrine beta-cells. Mol Endocrinol. 21:2255–2269.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Mizushima N, Levine B, Cuervo AM and
Klionsky DJ: Autophagy fights disease through cellular
self-digestion. Nature. 451:1069–1075. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Fujitani Y, Kawamori R and Watada H: The
role of autophagy in pancreatic beta-cell and diabetes. Autophagy.
5:280–282. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
He C and Klionsky DJ: Regulation
mechanisms and signaling pathways of autophagy. Annu Rev Genet.
43:67–93. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Singh R, Kaushik S, Wany Y, et al:
Authophagy regulates lipid metabolism. Nature. 458:1131–1135. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Eskelinen EL: Maturation of autophagic
vacuoles in Mammalian cells. Autophagy. 1:1–10. 2005. View Article : Google Scholar
|
|
18
|
Heckmann BL, Yang X, Zhang X and Liu J:
The autophagic inhibitor 3-methyladenine potently stimulates
PKA-dependent lipolysis in adipocytes. Br J Pharmacol. 168:163–171.
2013. View Article : Google Scholar :
|
|
19
|
Mizushima N, Yoshimori T and Levine B:
Methods in mammalian autophagy research. Cell. 140:313–326. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Klionsky DJ, Abdalla FC, Abeliovich H, et
al: Guidelines for the use and interpretation of assays for
monitoring autophagy. Autophagy. 8:445–544. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Mariño G and López-Otín C: Autophagy:
Molecular mechanisms, physiological functions and relevance in
human pathology. Cell Mol Life Sci. 61:1439–1454. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Scarlatti F, Maffei R, Beau I, Codogno P
and Ghidoni R: Role of non-canonical Beclin 1-independent autophagy
in cell death induced by resveratrol in human breast cancer cells.
Cell Death Differ. 15:1318–1329. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Edinger AL and Thompson CB: Defective
autophagy leads to cancer. Cancer Cell. 4:422–424. 2003. View Article : Google Scholar
|
|
24
|
Liang XH, Jackson S, Seaman M, et al:
Induction of autophagy and inhibition of tumorigenesis by beclin 1.
Nature. 402:672–676. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
25
|
Lee DY, Lee J and Sugden B: The unfolded
protein response and autophagy: Herpesviruses rule! J Virol.
83:1168–1172. 2009. View Article : Google Scholar :
|
|
26
|
Li J, Ni M, Lee B, Barron E, Hinton DR and
Lee AS: The unfolded protein response regulator GRP78/BiP is
required for endoplasmic reticulum integrity and stress-induced
autophagy in mammalian cells. Cell Death Differ. 15:1460–1471.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Geng J, Baba M, Nair U and Klionsky DJ:
Quantitative analysis of autophagy-related protein stoichometry by
fluorescence microscopy. J Cell Biol. 182:129–140. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Pickford F, Masliah E, Britschgi M, et al:
The autophagy-related protein beclin 1 shows reduced expression in
early Alzheimer disease and regulates amyloid beta accumulation in
mice. J Clin Invest. 118:2190–2199. 2008.PubMed/NCBI
|
|
29
|
Arsov I, Li X, Matthews G, et al:
BAC-mediated transgenic expression of fluorescent autophagic
protein Beclin 1 reveals a role for Beclin 1 in lymphocyte
development. Cell Death Differ. 15:1385–1395. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Gaytan M, Morales C, Sanchez-Criado JE and
Gaytan F: Immunolocalization of beclin 1, a bcl-2-binding,
autophagy-related protein, in the human ovary: possible relation to
life span of corpus luteum. Cell Tissue Res. 331:509–517. 2008.
View Article : Google Scholar
|
|
31
|
Dawson TR, Lazarus MD, Hetzer MW and Wente
SR: ER membrane-bending proteins are necessary for de novo nuclear
pore formation. J Cell Biol. 184:659–675. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Deniaud A, Sharaf el dein O, Maillier E,
et al: Endoplasmic reticulum stress induces calcium-dependent
permeability transition, mitochondrial outer membrane
permeabilization and apoptosis. Oncogene. 27:285–299. 2008.
View Article : Google Scholar
|
|
33
|
Yi M, Chi MH, Khang CH, et al: The ER
chaperone LHS1 is involved in asexual development and rice
infection by the blast fungus Magnaporthe oryzae. Plant Cell.
21:681–695. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
McCullough KD, Martindale JL, Klotz LO, Aw
TY and Holbrook NJ: Gadd153 sensitizes cells to endoplasmic
reticulum stress by down-regulating Bcl2 and perturbing the
cellular redox state. Mol Cell Biol. 21:1249–1259. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Kim SJ, Winter K, Nian C, Tsuneoka M, Koda
Y and McIntosh CH: Glucose-dependent insulinotropic polypeptide
(GIP) stimulation of pancreatic beta-cell survival is dependent
upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB)
signaling, inactivation of the forkhead transcription factor Foxo1
and down-regulation of bax expression. J Biol Chem.
280:22297–22307. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Hattori Y, Jojima T, Tomizawa A, et al: A
glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates
nitric oxide production and exerts anti-inflammatory action in
endothelial cells. Diabetologia. 53:2256–2263. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Gaspari T, Liu H, Welungoda I, et al: A
GLP-1 receptor agonist liraglutide inhibits endothelial cell
dysfunction and vascular adhesion molecule expression in an ApoE−/−
mouse model. Diab Vasc Dis Res. 8:117–124. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Curran KA and Miller J: Guidelines for
Animal-Assisted Interventions in Health Care Facilities. Am J
Infect Control. 37:257–258. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Bernales S, Schuck S and Walter P:
ER-phagy: selective autophagy of the endoplasmic reticulum.
Autophagy. 3:285–287. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Takács G, Papp S, Lukáts B, et al:
Homeostatic alterations after IL-1beta microinjection into the
nucleus accumbens of the rat. Appetite. 54:354–362. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Shimoda M, Kanda Y, Hamamoto S, et al: The
human glucagon-like peptide-1 analogue liraglutide preserves
pancreatic beta cells via regulation of cell kinetics and
suppression of oxidative and endoplasmic reticulum stress in a
mouse model of diabetes. Diabetologia. 54:1098–1108. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Fransson L, Dos Santos C, Wolbert P,
Sjoholm A, Rafacho A and Ortsater H: Liraglutide counteracts
obesity and glucose intolerance in a mouse model of
glucocorticoid-induced metabolic syndrome. Diabetol Metab Syndr.
6:32014. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chen ZF, Li YB, Han JY, et al: Liraglutide
prevents high glucose level induced insulinoma cells apoptosis by
targeting autophagy. Chin Med J (Engl). 126:937–941. 2013.
|
|
44
|
Hetz C: The unfolded protein response:
controlling cell fate decisions under ER stress and beyond. Nat Rev
Mol Cell Biol. 13:89–102. 2012.PubMed/NCBI
|
|
45
|
Zhang SH, Reddick RL, Piedrahita JA and
Maeda N: Spontaneous hypercholesterolemia and arterial lesions in
mice lacking apolipoprotein E. Science. 258:468–471. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Li L, Kim J and Boussiotis VA:
IL-1β-mediated signals preferentially drive conversion of
regulatory T cells but not conventional T cells into
IL-17-producing cells. J Immunol. 185:4148–4153. 2010. View Article : Google Scholar : PubMed/NCBI
|
