|
1
|
Tenbrock K, Juang YT, Kyttaris VC and
Tsokos GC: Altered signal transduction in SLE T cells. Rheumatology
(Oxford). 46. pp. 1525–1530. 2007, View Article : Google Scholar
|
|
2
|
Ohl K and Tenbrock K: Inflammatory
cytokines in systemic lupus erythematosus. J Biomed Biotechnol.
2011:4325952011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kinoshita K, Kishimoto K, Shimazu H, et
al: Successful treatment with retinoids in patients with lupus
nephritis. Am J Kidney Dis. 55:344–347. 2010. View Article : Google Scholar
|
|
4
|
Saxena R, Mahajan T and Mohan C: Lupus
nephritis: current update. Arthritis Res Ther. 13:2402011.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Bertsias G, Gordon C and Boumpas DT:
Clinical trials in systemic lupus erythematosus (SLE): lessons from
the past as we proceed to the future - the EULAR recommendations
for the management of SLE and the use of end-points in clinical
trials. Lupus. 17:437–442. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Thompson CB: Distinct roles for the
costimulatory ligands B7-1 and B7-2 in T helper cell
differentiation? Cell. 81:979–982. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
King CL, Xianli J, June CH, Abe R and Lee
KP: CD28-deficient mice generate an impaired Th2 response to
Schistosoma mansoni infection. Eur J Immunol. 26:2448–2455. 1996.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hart DN: Dendritic cells: unique leukocyte
populations which control the primary immune response. Blood.
90:3245–3287. 1997.PubMed/NCBI
|
|
9
|
Nossal GJ: Negative selection of
lymphocytes. Cell. 76:229–239. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Dong GC, Chuang PH, Chang KC, et al:
Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of
T-cell receptor. Pharm Res. 26:375–381. 2009. View Article : Google Scholar :
|
|
11
|
Fire A: RNA-triggered gene silencing.
Trends Genet. 15:358–363. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yelton DE and Scharff MD: Monoclonal
antibodies: a powerful new tool in biology and medicine. Annu Rev
Biochem. 50:657–680. 1981. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
McCoy KD and Le Gros G: The role of CTLA-4
in the regulation of T cell immune responses. Immunol Cell Biol.
77:1–10. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Shi Q, Gao ZY, Xie F, Wang LF, Gu YP, Yang
TJ, Huang L, Qian QH and Qiu YH: A novel monoclonal antibody
against human CD80 and its immune protection in a mouse lupus-like
disease. Int J Immunopathol Pharmacol. 24:583–593. 2011.PubMed/NCBI
|
|
15
|
Bradford MM: A rapid and sensitive method
for the quantitation of microgram quantities of protein utilizing
the principle of protein-dye binding. Anal Biochem. 72:248–254.
1976. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Satoh M and Reeves WH: Induction of
lupus-associated autoantibodies in BALB/c mice by intraperitoneal
injection of pristane. J Exp Med. 180:2341–2346. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Richards HB, Satoh M, Jennette JC, Croker
BP, Yoshida H and Reeves WH: Interferon-gamma is required for lupus
nephritis in mice treated with the hydrocarbon oil pristane. Kidney
Int. 60:2173–2180. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Dias N and Stein CA: Antisense
oligonucleotides: basic concepts and mechanisms. Mol Cancer Ther.
1:347–355. 2002.PubMed/NCBI
|
|
19
|
Zang X and Allison JP: The B7 family and
cancer therapy: Costimulation and coinhibition. Clin Cancer Res.
13:5271–5279. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Howard LM, Kohm AP, Castaneda CL and
Miller SD: Therapeutic blockade of TCR signal transduction and
co-stimulation in autoimmune disease. Curr Drug Targets Inflamm
Allergy. 4:205–216. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kremer JM, Genant HK, Moreland LW, et al:
Effects of abatacept in patients with methotrexate-resistant active
rheumatoid arthritis: a randomized trial. Ann Intern Med.
144:865–876. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Miyagishi M, Hayashi M and Taira K:
Comparison of the suppressive effects of antisense oligonucleotides
and siRNAs directed against the same targets in mammalian cells.
Antisense Nucleic Acid Drug Dev. 13:1–7. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Nakajima A, Azuma M, Kodera S, et al:
Preferential dependence of autoantibody production in murine lupus
on CD86 costimulatory molecule. Eur J Immunol. 25:3060–3069. 1995.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Cunnane G, Chan OT, Cassafer G, et al:
Prevention of renal damage in murine lupus nephritis by CTLA-4Ig
and cyclophosphamide. Arthritis Rheum. 50:1539–1548. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kubowicz P, Żelaszczyk D and Pękala E:
RNAi in clinical studies. Curr Med Chem. 20:1801–1816. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Talaat RM, Mohamed SF, Bassyouni IH and
Raouf AA: Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus
erythematosus (SLE) patients: Correlation with disease activity.
Cytokine. 72:146–153. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Dolff S, Bijl M, Huitema MG, Limburg PC,
Kallenberg CG and Abdulahad WH: Disturbed Th1, Th2, Th17 and T(reg)
balance in patients with systemic lupus erythematosus. Clin
Immunol. 141:197–204. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lazarus M, Hajeer AH, Turner D, et al:
Genetic variation in the interleukin 10 gene promoter and systemic
lupus erythematosus. J Rheumatol. 24:2314–2317. 1997.
|
|
29
|
Hasegawa K, Hayashi T and Maeda K:
Promotion of lupus in NZB x NZWF1 mice by plasmids encoding
interferon (IFN)-gamma but not by those encoding interleukin
(IL)-4. J Comp Pathol. 127:1–6. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Amel-Kashipaz MR, Huggins ML, Lanyon P,
Robins A, Todd I and Powell RJ: Quantitative and qualitative
analysis of the balance between type 1 and type 2
cytokine-producing CD8 (−) and CD8(+) T cells in systemic lupus
erythematosus. J Autoimmun. 17:155–163. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Solomou EE, Juang YT, Gourley MF, Kammer
GM and Tsokos GC: Molecular basis of deficient IL-2 production in T
cells from patients with systemic lupus erythematosus. J Immunol.
166:4216–4222. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Szegedi A, Simics E, Aleksza M, et al:
Ultraviolet-A1 phototherapy modulates Th1/Th2 and Tc1/Tc2 balance
in patients with systemic lupus erythematosus. Rheumatology
(Oxford). 44. pp. 925–931. 2005, View Article : Google Scholar
|
|
33
|
Svoboda P: Off-targeting and other
non-specific effects of RNAi experiments in mammalian cells. Curr
Opin Mol Ther. 9:248–257. 2007.PubMed/NCBI
|
|
34
|
Zhang JL, Sun DJ, Hou CM, et al: CD3 mAb
treatment ameliorated the severity of the cGVHD-induced lupus
nephritis in mice by up-regulation of Foxp3+ regulatory T cells in
the target tissue: kidney. Transpl Immunol. 24:17–25. 2010.
View Article : Google Scholar : PubMed/NCBI
|
