|
1
|
Ottaviani G and Jaffe N: The epidemiology
of osteosarcoma. Cancer Treat Res. 152:3–13. 2009. View Article : Google Scholar
|
|
2
|
Ritter J and Bielack SS: Osteosarcoma. Ann
Oncol. 21(Suppl 7): vii320–vii325. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Stiller CA, Bielack SS, Jundt G and
Steliarova-Foucher E: Bone tumours in European children and
adolescents, 1978–1997. Report from the automated childhood cancer
information system project. Eur J Cancer. 42:2124–2135. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Stiller CA, Craft AW and Corazziari I:
EUROCARE Working Group: Survival of children with bone sarcoma in
Europe since 1978: results from the EUROCARE study. Eur J Cancer.
37:760–766. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yang J, Yang D, Sun Y, et al: Genetic
amplification of the vascular endothelial growth factor (VEGF)
pathway genes, including VEGFA, in human osteosarcoma. Cancer.
117:4925–4938. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Quan GM and Choong PF: Anti-angiogenic
therapy for osteosarcoma. Cancer Metast Rev. 25:707–713. 2006.
View Article : Google Scholar
|
|
7
|
Dvorak HF: Vascular permeability
factor/vascular endothelial growth factor: A critical cytokine in
tumor angiogenesis and a potential target for diagnosis and
therapy. J Clin Oncol. 20:4368–4380. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Lee Y, Tokunaga T, Oshika Y, et al:
Cell-retained isoforms of vascular endothelial growth factor (VEGF)
are correlated with poor prognosis in osteosarcoma. Eur J Cancer.
35:1089–1093. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Takenaka K, Yamagishi SI, Jinnouchi Y,
Nakamura K, Matsui T and Imaizumi T: Pigment epithelium-derived
factor (PEDF)-induced apoptosis and inhibition of vascular
endothelial growth factor (VEGF) expression in MG63 human
osteosarcoma cells. Life Sci. 77:3231–3241. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Miller CW, Aslo A, Tsay C, et al:
Frequency and structure of p53 rearrangements in human
osteosarcoma. Cancer Res. 50:7950–7954. 1990.PubMed/NCBI
|
|
11
|
Mousses S, Mcauley L, Bell RS, Kandel R
and Andrulis IL: Molecular and immunohistochemical identification
of p53 alterations in bone and soft tissue sarcomas. Mod Pathol.
9:1–6. 1996.PubMed/NCBI
|
|
12
|
Eliseev R, Dong Y, Sampson E, et al:
Runx2-mediated activation of the Bax gene increases osteosarcoma
cell sensitivity to apoptosis. Oncogene. 27:3605–3614. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Onda M, Matsuda S, Higaki S, et al: ErbB-2
expression is correlated with poor prognosis for patients with
osteosarcoma. Cancer. 77:71–78. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Namløs HM, Meza-Zepeda LA, et al:
Modulation of the osteosarcoma expression phenotype by microRNAs.
PloS One. 7:e480862012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Irizarry RA, Hobbs B, Collin F, et al:
Exploration, normalization and summaries of high density
oligonucleotide array probe level data. Biostatistics. 4:249–264.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Gentleman R, Carey VJ, Huber W, Irizarry
RA and Dudoit S: Bioinformatics and computational biology solutions
using R and Bioconductor. 746718470. Springer; New York NY: 2005,
View Article : Google Scholar
|
|
17
|
Huang da W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2008. View Article : Google Scholar
|
|
18
|
Harris MA, Clark J, Ireland A, et al: The
Gene Ontology (GO) database and informatics resource. Nucleic Acids
Res. 32:D258–D261. 2004. View Article : Google Scholar
|
|
19
|
Lu M, Zhang Q, Deng M, et al: An analysis
of human microRNA and disease associations. PloS One. 3:e34202008.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Franceschini A, Szklarczyk D, Frankild S,
et al: STRING v9.1: Protein-protein interaction networks, with
increased coverage and integration. Nucleic Acids Res.
41:D808–D815. 2013. View Article : Google Scholar :
|
|
21
|
Saito R, Smoot ME, Ono K, et al: A travel
guide to Cytoscape plugins. Nat Med. 9:1069–1076. 2012.
|
|
22
|
Palla G, Derényi I, Farkas I and Vicsek T:
Uncovering the overlapping community structure of complex networks
in nature and society. Nature. 435:814–818. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Cui XR, Hou WR, Yang J, Hou Y and Peng ZS:
Cloning and sequence analysis of ribosomal protein L8 gene (RPL8)
from the (Ailuropoda melanoleuca). 2011 4th International
Conference on Biomedical Engineering and Informatics; Shanghai,
China. pp. 1407–1411. 2011
|
|
24
|
Yang J and Zhang W: New molecular insights
into osteosarcoma targeted therapy. Curr Opin Oncol. 25:398–406.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Salas S, Jézéquel P, Campion L, Deville
JL, Chibon F, Bartoli C, Gentet JC, Charbonnel C, Gouraud W,
Voutsinos-Porche B, et al: Molecular characterization of the
response to chemotherapy in conventional osteosarcomas: Predictive
value of HSD17B10 and IFITM2. Int J Cancer. 125:851–860. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Montanaro L, Mazzini G, Barbieri S, et al:
Different effects of ribosome biogenesis inhibition on cell
proliferation in retinoblastoma protein-and p53-deficient and
proficient human osteosarcoma cell lines. Cell Prolif. 40:532–549.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Fukami K: Structure, regulation and
function of phospholipase C isozymes. J Biochem. 131:293–299. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Noh DY, Kang H, Kim YC, et al: Expression
of phospholipase C-gamma 1 and its transcriptional regulators in
breast cancer tissues. Anticancer Res. 18:2643–2648. 1997.
|
|
29
|
Mamoune A, Kassis J, Kharait S, Kloeker S,
Manos E, Jones DA and Wells A: DU145 human prostate carcinoma
invasiveness is modulated by urokinase receptor (uPAR) downstream
of epidermal growth factor receptor (EGFR) signaling. Exp Cell Res.
299:91–100. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kochhar KS and Iyer AP: Hepatocyte growth
factor induces activation of Nck and phospholipase C-γ in lung
carcinoma cells. Cancer Lett. 104:163–169. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Kassis J, Radinsky R and Wells A: Motility
is rate-limiting for invasion of bladder carcinoma cell lines. Int
J Biochem Cell Biol. 34:762–775. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhang B, Wu Q, Ye XF, Liu S, Lin XF and
Chen MC: Roles of PLC-gamma2 and PKCalpha in TPA-induced apoptosis
of gastric cancer cells. World J Gastroenterol. 9:2413–2418.
2003.PubMed/NCBI
|
|
33
|
Dong S, Ma L, Xu N, et al: Research on the
reactivation of Syk expression caused by the inhibition of DNA
promoter methylation in the lung cancer. Neoplasma. 58:89–95. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Luo P, Yang X, Ying M, et al:
Retinoid-suppressed phosphorylation of RARα mediates the
differentiation pathway of osteosarcoma cells. Oncogene.
29:2772–2783. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Agoston AT, Argani P, De Marzo AM, Hicks
JL and Nelson WG: Retinoblastoma pathway dysregulation causes DNA
methyltrans-ferase 1 overexpression in cancer via MAD2-mediated
inhibition of the anaphase-promoting complex. Am J Pathol.
170:1585–1593. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Yu L, Guo WC, Zhao SH, Tang J and Chen JL:
Mitotic arrest defective protein 2 expression abnormality and its
clinicopathologic significance in human osteosarcoma. Apmis.
118:222–229. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Yu L, Guo W, Zhao S, Tang J and Liu J:
Knockdown of Mad2 induces osteosarcoma cell apoptosis-involved
Rad21 cleavage. J Orthop Sci. 16:814–820. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Shichiri M, Yoshinaga K, Hisatomi H,
Sugihara K and Hirata Y: Genetic and epigenetic inactivation of
mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to
survival. Cancer Res. 62:13–17. 2002.PubMed/NCBI
|
|
39
|
Bischoff JR, Anderson L, Zhu Y, et al: A
homologue of Drosophila aurora kinase is oncogenic and amplified in
human colorectal cancers. EMBO J. 17:3052–3065. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Branca M, Giorgi C, Santini D, et al:
Survivin as a marker of cervical intraepithelial neoplasia and
high-risk human papillomavirus and a predictor of virus clearance
and prognosis in cervical cancer. Am J Clin Pathol. 124:113–121.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Hayama S, Daigo Y, Yamabuki T, et al:
Phosphorylation and activation of cell division cycle associated 8
by aurora kinase B plays a significant role in human lung
carcinogenesis. Cancer Res. 67:4113–4122. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Pickard MR, Green AR, Ellis IO, et al:
Dysregulated expression of Fau and MELK is associated with poor
prognosis in breast cancer. Breast Cancer Res. 11:R602009.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Lin ML, Park JH, Nishidate T, Nakamura Y
and Katagiri T: Involvement of maternal embryonic leucine zipper
kinase (MELK) in mammary carcinogenesis through interaction with
Bcl-G, a pro-apoptotic member of the Bcl-2 family. Breast Cancer
Res. 9:R172007. View
Article : Google Scholar : PubMed/NCBI
|
|
44
|
Gray D, Jubb AM, Hogue D, et al: Maternal
embryonic leucine zipper kinase/murine protein serine-threonine
kinase 38 is a promising therapeutic target for multiple cancers.
Cancer Res. 65:9751–9761. 2005. View Article : Google Scholar : PubMed/NCBI
|
