|
1
|
Heller DA, de Faire U, Pedersen N, Dahlén
G and McClearn GE: Genetic and environmental influences on serum
lipid levels in twins. N Eng J Med. 328:1150–1156. 1993. View Article : Google Scholar
|
|
2
|
Pérusse L, Rice T, Després JP, Bergeron J,
Province MA, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH and
Bouchard C: Familial resemblance of plasma lipids, lipoproteins and
postheparin lipoprotein and hepatic lipase in the HERITAGE Family
Study. Arterioscler Thromb Vasc Biol. 17:3263–3269. 1997.
View Article : Google Scholar
|
|
3
|
Global Lipids Genetics Consortium; Willer
CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S,
Ganna A, Chen J, Buchkovich ML, et al: Discovery and refinement of
loci associated with lipid levels. Nat Genet. 45:1274–1283. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kirillova OO: Modern concepts of gene
polymorphism, which regulate lipid metabolism. Vopr Pitan.
81:48–52. 2012.
|
|
5
|
Fujimaki T, Kato K, Oguri M, Yohida T,
Horibe H, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, et al:
Association of polymorphism of BTN2A1 with dyslipidmemia in East
Asian populations. Exp Ther Med. 2:745–749. 2011.PubMed/NCBI
|
|
6
|
Horibe H, Ueyama C, Fujimaki T, Oguri M,
Kato K, Ichihara S and Yamada Y: Association of a polymorphism of
BTN2A1 with dyslipidemia in community-dwelling individuals. Mol Med
Rep. 9:808–812. 2014.PubMed/NCBI
|
|
7
|
Hiramatsu M, Oguri M, Kato K, Horibe H,
Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Shin DJ, et
al: Synergistic effects of genetic variants of APOA5 and BTN2A1 on
dyslipidemia or metabolic syndrome. Int J Mol Med. 30:185–192.
2012.PubMed/NCBI
|
|
8
|
Schunkert H, König IR, Kathiresan S,
Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M,
Gieger C, et al: Large-scale association analysis identifies 13 new
susceptibility loci for coronary artery disease. Nat Genet.
43:333–338. 2011. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
CARDIoGRAMplusC4D Consortium; Deloukas P,
Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR,
Ingelsson E, Saleheen D, Erdmann J, et al: Large-scale association
analysis identifies new risk loci for coronary artery disease. Nat
Genet. 45:25–33. 2013. View
Article : Google Scholar
|
|
10
|
Itoh Y, Mizuki N, Shimada T, Azuma F,
Itakura M, Kashiwase K, Kikkawa E, Kulski JK, Satake M and Inoko H:
High-throughput DNA typing of HLA-A, -B, -C and -DRB1 loci by a
PCR-SSOP-Luminex method in the Japanese population. Immunogenetics.
57:717–729. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Waterworth DM, Ricketts SL, Song K, Chen
L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W, Yuan X, Lim N, et al:
Genetic variants influencing circulating lipid levels and risk of
coronary artery disease. Arterioscler Thromb Vasc Biol.
30:2264–2276. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Teslovich TM, Musunuru K, Smith AV,
Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S,
Chasman DI, Willer CJ, et al: Biological, clinical and population
relevance of 95 loci for blood lipids. Nature. 466:707–713. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Nakayama K, Yanagisawa Y, Ogawa A,
Ishizuka Y, Munkhtulga L, Charupoonphol P, Supannnatas S, Kuartei
S, Chimedregzen U, Koda Y, et al: High prevalence of an
anti-hypertriglyceridemic variant of the MLXIPL gene in Central
Asia. J Hum Genet. 56:828–833. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kathiresan S, Willer CJ, Peloso GM,
Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y,
Tanaka T, et al: Common variants at 30 loci contribute to polygenic
dyslipidemia. Nat Genet. 41:56–65. 2009. View Article : Google Scholar
|
|
15
|
Kathiresan S, Melander O, Guiducci C,
Surti A, Burtt NP, Rieder MJ, Cooper GM, Roos C, Voight BF,
Havulinna AS, et al: Six new loci associated with blood low-density
lipoprotein cholesterol, high-density lipoprotein cholesterol or
triglycerides in humans. Nat Genet. 40:189–197. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Willer CJ, Sanna S, Jackson AU, Scuteri A,
Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS,
Stringham HM, et al: Newly identified loci that influence lipid
concentrations and risk of coronary artery disease. Nat Genet.
40:161–169. 2008. View
Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yan SK, Cheng XQ, Song YH, Xiao XH, Bi N
and Chen BS: Apolipoprotein A5 gene polymorphism -1131T->C:
Association with plasma lipids and type 2 diabetes mellitus with
coronary heart disease in Chinese. Clin Chem Lab Med. 43:607–612.
2005. View Article : Google Scholar
|
|
18
|
Klos KL, Sing CF, Boerwinkle E, Hamon SC,
Rea TJ, Clark A, Fornage M and Hixson JE: Consistent effects of
genes involved in reverse cholesterol transport on plasma lipid and
apolipo-protein levels in CARDIA participants. Arterioscler Thromb
Vasc Biol. 26:1828–1836. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ken-Dror G, Goldbourt U and Dankner R:
Different effects of apolipoprotein A5 SNPs and haplotypes on
triglyceride concentration in three ethnic origins. J Hum Genet.
55:300–307. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Jakel H, Nowak M, Helleboid-Chapman A,
Fruchart-Najib J and Fruchart JC: Is apolipoprotein A5 a novel
regulator of triglyceride-rich lipoproteins? Ann Med. 38:2–10.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Galernabi M, Lor K, Jin J, Chai F and
Santanam N: The paradox of ApoA5 modulation of triglycerides:
Evidence from clinical and basic research. Clin Biohem. 46:12–19.
2013. View Article : Google Scholar
|
|
22
|
Vargas VR, Bonatto SL, Macagnan FE, Feoli
AM, Alho CS, Santos ND and Schmitt VM: Influence of the 48867
A>C (Asp358Ala) IL6R polymorphism on response to a lifestyle
modification intervention in individuals with metabolic syndrome.
Genet Mol Res. 12:3893–3991. 2013. View Article : Google Scholar
|
|
23
|
Esteve E, Villuendas G, Mallolas J,
Vendrell J, López-Bermejo A, Rodríguez M, Recasens M, Ricart W, San
Millán JL, Escobar-Morreale H, et al: Polymorphisms in the
interleukin-6 receptor gene are associated with body mass index and
with characteristics of the metabolic syndrome. Clin Endocrinol
(Oxf). 65:88–91. 2006. View Article : Google Scholar
|
|
24
|
Hardardόttir I, Grünfeld C and Feingold
KR: Effects of endotoxin and cytokines on lipid metabolism. Curr
Opin Lipidol. 5:207–215. 1994. View Article : Google Scholar
|
|
25
|
Chu NF, Lin FH, Chin HC and Hong YJ:
Association between interleukin-6 receptor gene variations and
atherosclerotic lipid profiles among young adolescents in Taiwan.
Lipids Health Dis. 10:1362011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Jiang CQ, Lam TH, Liu B, Lin JM, Yue XJ,
Jin YL, Cheung BM and Thomas GN: Interleukin-6 receptor gene
polymorphism modulates interleulin-6 levels and the metabolic
syndrome: GBCS-CVD. Obesity (Silver Spring). 18:1969–1974. 2010.
View Article : Google Scholar
|
|
27
|
Gu X, Zhao F, Zheng M, Fei X, Chen X,
Huang S, Xie Y and Mao Y: Cloning and characterization of a gene
encoding the human putative ubiquitin conjugating enzyme E2Z
(UBE2Z). Mol Biol Rep. 34:183–188. 2007. View Article : Google Scholar
|
|
28
|
Alssema M, Rijkelijkhuizen JM, Holst JJ,
Teerlink T, Scheffer PG, Eekhoff EM, Gastaldelli A, Mari A, Hart
LM, Nijpels G, et al: Preserved GLP-1 and exaggerated GIP secretion
in type 2 diabetes and relationships with triglycerides and ALT.
Eur J Endocrinol. 169:421–430. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
International Consortium for Blood
Pressure Genome-Wide Association Studies; Ehret GB, Munroe PB, Rice
KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert
GC, et al: Genetic variants in novel pathways influence blood
pressure and cardiovascular disease risk. Nature. 478:103–109.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Turpeinen H, Raitoharju E, Oksanen A,
Oksala N, Levula M, Lyytikäinen LP, Järvinen O, Creemers JW,
Kähönen M, Laaksonen R, et al: Proprotein convertases in human
athero-sclerotic plaques: The overexpression of FURIN and its
substrate cytokines BAFF and APRIL. Atherosclerosis. 219:799–806.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Samani NJ, Braund PS, Erdmann J, Götz A,
Tomaszewski M, Linsel-Nitschke P, Hajat C, Mangino M, Hengstenberg
C, Stark K, et al: The novel genetic variant predisposing to
coronary artery disease in the region of the PSRC1 and CELSR2 genes
on chromosome 1 associates with serum cholesterol. J Mol Med
(Berl). 86:1233–1241. 2008. View Article : Google Scholar
|
|
32
|
Samani NJ, Erdmann J, Hall AS,
Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund
P, Wichmann HE, et al: Genomewide association analysis of coronary
artery disease. N Engl J Med. 357:443–453. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Kleber ME, Renner W, Grammer TB,
Linsel-Nitschke P, Boehm BO, Winkelmann BR, Bugert P, Hoffmann MM
and März W: Association of the single nucleotide polymorphism
rs599839 in the vicinity of the sortilin 1 gene with LDL and
triglyceride metabolism, coronary heart disease and myocardial
infarction: The ludwigshafen risk and cardiovascular health study.
Atherosclerosis. 209:492–497. 2010. View Article : Google Scholar
|
|
34
|
Muendlein A, Geller-Rhomberg S, Saely CH,
Winder T, Sonderegger G, Rein P, Beer S, Vonbank A and Drexel H:
Significant impact of chromosomal locus 1p13.3 on serum LDL
cholesterol and on angiographically characterized coronary
atherosclerosis. Atherosclerosis. 206:494–499. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Wang AZ, Li L, Zhang B, Shen GQ and Wang
QK: Association of SNP rs17465637 on chromosome 1q451 and rs599839
on 1p13.3 with myocardial infarction in an American caucasian
population. Ann Hum Genet. 75:475–482. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Vincent JB, Skaug J and Scherer SW: The
human homologue of flamingo, EGFL2, encode a brain-expressed large
cadherin-like protein which epidermal growth factor-like domains
and maps to chromosome 1p13.3–p21.1. DNA Res. 7:233–235. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Hsieh PC, Chang JC, Sun WT, Hsieh SC, Wang
MC and Wang FF: p53 down-stream target DDA3 is a novel
microtubule-associated protein that interacts with end-binding
protein EB3 and activates beta-catenin pathway. Oncogene.
26:4928–4940. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Strong A and Rader DJ: Sortilin as a
regulator of lipoprotein metabolism. Curr Atheroscler Rep.
14:211–218. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Jansen P, Giehl K, Nyengaard JR, Teng K,
Lioubinski O, Sjoegaard SS, Breiderhoff T, Gotthardt M, Lin F,
Eilers A, et al: Roles for the pro-neurotrophin receptor sortilin
in neuronal development, aging and brain injury. Nat Neurosci.
10:1449–1457. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
40
|
Nielsen MS, Jacobsen C, Olivecrona G,
Gliemann J and Petersen CM: Sortilin/neurotensin receptor-3 binds
and mediates degradation of lipoprotein lipase. J Biol Chem.
274:8832–8836. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Nilsson SK, Christensen S, Raarup MK, Ryan
RO, Nielsen MS and Olivecrona G: Endocytosis of apolipoprotein A-V
by members of the low density lipoprotein receptor and the VPS10p
domain receptor families. J Biol Chem. 283:25920–25927. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Arvind P, Nair J, Jambunathan S, Kakkar VV
and Shanker J: CELSR2-PSCR1-SORT1 gene expression and association
with coronary artery disease and plasma lipid levels in an Asian
Indian cohort. J Cardiol. 64:339–346. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Humphries AD, Streimann IC, Stojanovski D,
Johnston AJ, Yano M, Hoogenraad NJ and Ryan MT: Dissection of the
mitochondrial import and assembly pathway for human Tom40. J Biol
Chem. 280:11535–11543. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Cruchaga C, Nowotny P, Kauwe JS, Ridge PG,
Mayo K, Bertelsen S, Hinrichs A, Fagan AM, Holtzman DM, Morris JC,
et al: Association and expression analyses with single-nucleotide
polymorphisms in TOMM40 in Alzheimer disease. Arch Neurol.
68:1013–1019. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Yu CE, Seltman H, Peskind ER, Galloway N,
Zhou PX, Rosenthal E, Wijsman EM, Tsuang DW, Devlin B and
Schellenberg GD: Comprehensive analysis of APOE and selected
proximate markers for late-onset Alzheimer disease: Pattern of
linkage disequilibrium and disease/marker association. Genomics.
89:655–665. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Bennet AM, Di Angelantonio E, Ye Z,
Wensley F, Dahlin A, Ahlbom A, Keavney B, Collins R, Wiman B, de
Faire U, et al: Association of apolipoprotein E genotypes with
lipid levels and coronary risk. JAMA. 298:1300–1311. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Deelen J, Beekman M, Uh HW, Helmer Q,
Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman
HE, et al: Genome-wide association study identifies a single major
locus contributing to survival into old age; the APOE locus
revisited. Aging Cell. 10:686–698. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Nebel A, Kleindorp R, Caliebe A, Nothnagel
M, Blanché H, Junge O, Wittig M, Ellinghaus D, Flachsbart F,
Wichmann HE, et al: A genome-wide association study confirms APOE
as the major gene influencing survival in long-lived individuals.
Mech Ageing Dev. 132:324–330. 2011. View Article : Google Scholar : PubMed/NCBI
|
