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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2015 Volume 12 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Gene therapy for ocular diseases meditated by ultrasound and microbubbles (Review)

Caifeng Wan, Fenghua Li, Hongli Li
Pages: 4803-4814
Published online on: 07 July 2015

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Article Open Access

Propofol suppresses proliferation and invasion of glioma cells by upregulating microRNA-218 expression

Jinquan Xu, Weiyun Xu, Jiaqun Zhu
Pages: 4815-4820
Published online on: 01 July 2015

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Article Open Access

MicroRNA let-7b-regulated epidermal stem cell proliferation in hypertrophied anal papillae

Hong Lu, Xiang He, Qingming Wang, De Zheng, Ye Han, Wei Yang, Te Liu
Pages: 4821-4828
Published online on: 02 July 2015

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Article Open Access

Bioinformatics analysis to identify the differentially expressed genes of glaucoma

Xiang Yan, Fei Yuan, Xiuping Chen, Chunqiong Dong
Pages: 4829-4836
Published online on: 02 July 2015

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Article Open Access

Restored expression levels of TET1 decrease the proliferation and migration of renal carcinoma cells

Min Fan, Xiaozhou He, Xianlin Xu
Pages: 4837-4842
Published online on: 08 July 2015

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Article Open Access

Polyphenol-rich extract of Salvia chinensis exhibits anticancer activity in different cancer cell lines, and induces cell cycle arrest at the G0/G1-phase, apoptosis and loss of mitochondrial membrane potential in pancreatic cancer cells Retraction in /10.3892/mmr.2021.12101

Quan Zhao, Xue‑Chen Huo, Fu‑Dong Sun, Rui‑Qian Dong
Pages: 4843-4850
Published online on: 13 July 2015

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Article Open Access

Ethyl acetate extract of Hypericum japonicum induces apoptosis via the mitochondria-dependent pathway in vivo and in vitro

Qunchuan Zhuang, Jing Li, Youqin Chen, Jiumao Lin, Faze Lai, Xuzheng Chen, Xindeng Lin, Jun Peng
Pages: 4851-4858
Published online on: 16 July 2015

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Article Open Access

Effect of targeted ovarian cancer therapy using amniotic fluid mesenchymal stem cells transfected with enhanced green fluorescent protein-human interleukin-2 in vivo

Qi You, Yuan Yao, Yuanlong Zhang, Songbin Fu, Mei Du, Guangmei Zhang
Pages: 4859-4866
Published online on: 13 July 2015

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Article Open Access

YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells

Xia Sheng, Wen‑Bin Li, De‑Lin Wang, Ke‑Hong Chen, Jian‑Jia Cao, Zhao Luo, Jiang He, Mei‑Cai Li, Wu‑Jiang Liu, Chao Yu
Pages: 4867-4876
Published online on: 29 June 2015

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Article Open Access

Presence and function of microRNA-92a in chondrogenic ATDC5 and adipose-derived mesenchymal stem cells

Changhe Hou, Ziji Zhang, Zhiqi Zhang, Peihui Wu, Xiaoyi Zhao, Ming Fu, Puyi Sheng, Yan Kang, Weiming Liao
Pages: 4877-4886
Published online on: 01 July 2015

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Article Open Access

Minocycline inhibits PARP‑1 expression and decreases apoptosis in diabetic retinopathy

Ying Wu, Yongdong Chen, Qiang Wu, Lili Jia, Xinhua Du
Pages: 4887-4894
Published online on: 08 July 2015

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Article Open Access

Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70

Wei He, Yun Zhuang, Liangzhi Wang, Lei Qi, Binfang Chen, Mei Wang, Dong Shao, Jianping Chen
Pages: 4895-4900
Published online on: 09 July 2015

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Article Open Access

HOXB7-S3 inhibits the proliferation and invasion of MCF-7 human breast cancer cells

Rui Ma, Dan Zhang, Peng-Chao Hu, Qun Li, Cong-Yao Lin
Pages: 4901-4908
Published online on: 01 July 2015

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Article Open Access

Gonadotropin‑releasing hormone inhibits the proliferation and motility of nasopharyngeal carcinoma cells

Loong Hung Teng, Munirah Ahmad, Wayne Tiong Weng Ng, Subathra Sabaratnam, Maria Ithaya Rasan, Ishwar Parhar, Alan Soo Beng Khoo
Pages: 4909-4916
Published online on: 03 July 2015

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Article Open Access

MicroRNA‑21 regulates the expression of BTG2 in HepG2 liver cancer cells

Bijing Mao, He Xiao, Zhimin Zhang, Dong Wang, Ge Wang
Pages: 4917-4924
Published online on: 07 July 2015

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Article Open Access

Microarray based analysis of gene regulation by microRNA in intervertebral disc degeneration

Peng Hu, Bo Feng, Guanglin Wang, Bin Ning, Tanghong Jia
Pages: 4925-4930
Published online on: 02 July 2015

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Article Open Access

Beneficial reciprocal effects of bone marrow stromal cells and Schwann cells from adult rats in a dynamic co‑culture system in vitro without intercellular contact

Li‑Na Zhou, Xiao‑Jun Cui, Kai‑Xin Su, Xiao‑Hong Wang, Jin‑Hua Guo
Pages: 4931-4938
Published online on: 02 July 2015

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Article Open Access

Ischemic preconditioning maintains the immunoreactivities of glucokinase and glucokinase regulatory protein in neurons of the gerbil hippocampal CA1 region following transient cerebral ischemia

Young Shin Cho, Jun Hwi Cho, Bich‑Na Shin, Geum‑Sil Cho, In Hye Kim, Joon Ha Park, Ji Hyeon Ahn, Taek Geun Ohk, Byung‑Ryul Cho, Young‑Myeong Kim, Seongkweon Hong, Moo‑Ho Won, Jae‑Chul Lee
Pages: 4939-4946
Published online on: 02 July 2015

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Article Open Access

Functional and protein‑protein interaction network analysis of colorectal cancer induced by ulcerative colitis

Yong Dai, Jin‑Bo Jiang, Yan‑Lei Wang, Zu‑Tao Jin, San‑Yuan Hu
Pages: 4947-4958
Published online on: 20 July 2015

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Article Open Access

Dickkopf‑related protein 1 induces angiogenesis by upregulating vascular endothelial growth factor in the synovial fibroblasts of patients with temporomandibular joint disorders

Sheng‑Jun Jiang, Wei Li, Ying‑Jie Li, Wei Fang, Xing Long
Pages: 4959-4966
Published online on: 20 July 2015

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Article Open Access

Transplantation of vascular endothelial growth factor 165‑transfected endothelial progenitor cells for the treatment of limb ischemia

Sheng Wang, Zhong Chen, Xiaobin Tang, Hui Liu, Liao Yang, Yanyang Wang
Pages: 4967-4974
Published online on: 20 July 2015

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Article Open Access

Functional analysis of the nasopharyngeal carcinoma primary tumor‑associated gene interaction network

Fengwei An, Zhiqiang Zhang, Ming Xia
Pages: 4975-4980
Published online on: 20 July 2015

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Article Open Access

Effects of brain‑derived neurotrophic factor and neurotrophin‑3 on the neuronal differentiation of rat adipose‑derived stem cells

Wenchen Ji, Xiaowei Zhang, Le Ji, Kunzheng Wang, Yusheng Qiu
Pages: 4981-4988
Published online on: 20 July 2015

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Article Open Access

MicroRNA‑20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing early growth response 2 expression

Wenkun Zhuo, Weiming Ge, Guolin Meng, Shuaijun Jia, Xiang Zhou, Jian Liu
Pages: 4989-4994
Published online on: 20 July 2015

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Article Open Access

Galectin-3-induced oxidized low-density lipoprotein promotes the phenotypic transformation of vascular smooth muscle cells

Lei Tian, Kan Chen, Jiatian Cao, Zhihua Han, Lin Gao, Yue Wang, Yuqi Fan, Changqian Wang
Pages: 4995-5002
Published online on: 13 July 2015

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Article Open Access

Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells

Victor Aguiriano‑Moser, Bernhard Svejda, Zeng‑Xia Li, Sonja Sturm, Hermann Stuppner, Elisabeth Ingolic, Harald Höger, Veronika Siegl, Nathalie Meier-Allard, Anton Sadjak, Roswitha Pfragner
Pages: 5003-5011
Published online on: 07 July 2015

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Article Open Access

Anticancer and apoptotic activities of oleanolic acid are mediated through cell cycle arrest and disruption of mitochondrial membrane potential in HepG2 human hepatocellular carcinoma cells Retraction in /10.3892/mmr.2021.12079

Yue‑Yong Zhu, Hong‑Yan Huang, Yin‑Lian Wu
Pages: 5012-5018
Published online on: 02 July 2015

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Article Open Access

MicroRNA‑197 reverses the drug resistance of fluorouracil‑induced SGC7901 cells by targeting mitogen‑activated protein kinase 1

Hai‑Lin Xiong, Si‑Wei Zhou, Ai‑Hua Sun, Ying He, Jun Li, Xia Yuan
Pages: 5019-5025
Published online on: 07 July 2015

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Article Open Access

Protective effects of SS31 on t‑BHP induced oxidative damage in 661W cells

Wei Ma, Xiaobo Zhu, Xiaoyan Ding, Tao Li, Yijun Hu, Xuting Hu, Lin Yuan, Lei Lei, Andina Hu, Yan Luo, Shibo Tang
Pages: 5026-5034
Published online on: 07 July 2015

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Article Open Access

Promotion of mitochondrial energy metabolism during hepatocyte apoptosis in a rat model of acute liver failure

Li‑Yan Chen, Baoshan Yang, Li Zhou, Feng Ren, Zhong‑Ping Duan, Ying‑Ji Ma
Pages: 5035-5041
Published online on: 02 July 2015

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Article Open Access

Aberrant Wnt/β‑catenin signaling and elevated expression of stem cell proteins are associated with osteosarcoma side population cells of high tumorigenicity

Xi‑Jun Yi, Yu‑Hua Zhao, Li‑Xiang Qiao, Chun‑Lei Jin, Jing Tian, Qiu‑Shi Li
Pages: 5042-5048
Published online on: 02 July 2015

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Article Open Access

Substrate-specific gene expression profiles in different kidney cell types are associated with Fabry disease

Youn‑Jeong Shin, Yeo Jin Jeon, Namhee Jung, Joo‑Won Park, Hae‑Young Park, Sung‑Chul Jung
Pages: 5049-5057
Published online on: 01 July 2015

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Article Open Access

A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms

Jianping Jia, Song Dai, Xinghe Sun, Yuehong Sang, Zhenming Xu, Jie Zhang, Xiaofeng Cui, Jinhui Song, Xing Guo
Pages: 5058-5064
Published online on: 08 July 2015

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Article Open Access

Cardiac effects of the c.1583 C→G LMNA mutation in two families with Emery‑Dreifuss muscular dystrophy

Li Zhang, Hongrui Shen, Zhe Zhao, Qi Bing, Jing Hu
Pages: 5065-5071
Published online on: 08 July 2015

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Article Open Access

Steatocystoma multiplex is associated with the R94C mutation in the KRTl7 gene

Qiao Liu, Weiwei Wu, Jiejie Lu, Ping Wang, Feng Qiao
Pages: 5072-5076
Published online on: 08 July 2015

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Article Open Access

Effects of Ras homolog gene family, member C gene silencing combined with rapamycin on hepatocellular carcinoma cell growth

Shu‑Li Xie, Ming‑Guang Zhu, Guo‑Fu Chen, Guang‑Yi Wang, Guo‑Yue Lv
Pages: 5077-5085
Published online on: 08 July 2015

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Article Open Access

Girdin regulates the migration and invasion of glioma cells via the PI3K‑Akt signaling pathway

Weimin Ni, Yan Fang, Lei Tong, Zhaoxue Tong, Fuxin Yi, Jianwu Qiu, Rui Wang, Xiaojie Tong
Pages: 5086-5092
Published online on: 07 July 2015

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Article Open Access

Genetically modified human placenta‑derived mesenchymal stem cells with FGF‑2 and PDGF‑BB enhance neovascularization in a model of hindlimb ischemia

Tao Yin, Sisi He, Chao Su, Xiancheng Chen, Dongmei Zhang, Yang Wan, Tinghong Ye, Guobo Shen, Yongsheng Wang, Huashan Shi, Li Yang, Yuquan Wei
Pages: 5093-5099
Published online on: 20 July 2015

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Article Open Access

8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Pages: 5100-5108
Published online on: 03 July 2015

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Article

Hepatitis C virus NS3 protein modulates the biological behaviors of malignant hepatocytes by altering the expression of host cell microRNA

Jun Zhang, Yasuhito Ishigaki, Tsutomu Takegami
Pages: 5109-5115
Published online on: 03 July 2015

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Article

Expression of nephrin in the human placenta and fetal membranes

Bo Hyon Yun, Seung Mi Lee, Hee Young Cho, Ji Young Kim, Ga Hyun Son, Young Han Kim, Yong Won Park, Beom Jin Lim, Ja Young Kwon
Pages: 5116-5120
Published online on: 06 July 2015

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Article

MicroRNA‑506 participates in pancreatic cancer pathogenesis by targeting PIM3

Jundong Du, Xi Zheng, Shouwang Cai, Ziman Zhu, Jingwang Tan, Bin Hu, Zhiqiang Huang, Huabo Jiao
Pages: 5121-5126
Published online on: 22 July 2015

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Article

Derivation and growth characteristics of dental pulp stem cells from patients of different ages

Wei Wu, Jian Zhou, Chong‑Tao Xu, Jie Zhang, Yan‑Jiao Jin, Geng‑Lin Sun
Pages: 5127-5134
Published online on: 21 July 2015

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Article

Upregulation of microRNA‑138‑5p inhibits pancreatic cancer cell migration and increases chemotherapy sensitivity

Chao Yu, Min Wang, Meiyuan Chen, Yang Huang, Jianxin Jiang
Pages: 5135-5140
Published online on: 02 July 2015

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Article

Biological characteristics of the A1762T/G1764A mutant strain of hepatitis B virus in vivo

Xiao‑Hua Leng, En‑Qiang Chen, Ling‑Yao Du, Lang Bai, Dao‑Ying Gong, Xing Cheng, Fei‑Jun Huang, Hong Tang
Pages: 5141-5148
Published online on: 09 July 2015

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Article

A novel endoplasmic reticulum stress‑induced apoptosis model using tunicamycin in primary cultured neonatal rat cardiomyocytes

Mingzhi Shen, Lin Wang, Xiaowang Guo, Qiao Xue, Cong Huo, Xing Li, Li Fan, Xiaoming Wang
Pages: 5149-5154
Published online on: 03 July 2015

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Article

Downregulation of microRNA‑146a inhibits ovarian granulosa cell apoptosis by simultaneously targeting interleukin‑1 receptor‑associated kinase and tumor necrosis factor receptor‑associated factor 6

Xi Chen, Mingxuan Xie, Da Liu, Ke Shi
Pages: 5155-5162
Published online on: 03 July 2015

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Article

A novel brain metastasis xenograft model for convection‑enhanced delivery of targeted toxins via a micro‑osmotic pump system enabled for real‑time bioluminescence imaging

Jun Huang, Yan Michael Li, Quan Cheng, Daniel A. Vallera, Walter A. Hall
Pages: 5163-5168
Published online on: 22 July 2015

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Article

Dronedarone does not affect infarct volume as assessed by magnetic resonance imaging in a porcine model of myocardial infarction

Josefine Linke, Kirsten Utpatel, Carmen Wolke, Matthias Evert, Jens‑Peter Kühn, Alicja Bukowska, Andreas Goette, Uwe Lendeckel, Barbara Peters
Pages: 5169-5178
Published online on: 13 July 2015

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Article

Comparison of ovarian cancer markers in endometriosis favours HE4 over CA125

Brett Mckinnon, Michael D. Mueller, Konstantinos Nirgianakis, Nick A. Bersinger
Pages: 5179-5184
Published online on: 08 July 2015

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Article

Coupled aggregation of mitochondrial single-strand DNA-binding protein tagged with Eos fluorescent protein visualizes synchronized activity of mitochondrial nucleoids

Tomáš Olejár, David Pajuelo‑Reguera, Lukáš Alán, Andrea Dlasková, Petr Ježek
Pages: 5185-5190
Published online on: 16 July 2015

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Article

Decoy receptor 3 regulates the expression of tryptophan hydroxylase 1 in rheumatoid synovial fibroblasts

Toshihisa Maeda, Yasushi Miura, Koji Fukuda, Shinya Hayashi, Masahiro Kurosaka
Pages: 5191-5196
Published online on: 20 July 2015

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Article

Hydrogen sulfide attenuates doxorubicin‑induced cardiotoxicity by inhibiting calreticulin expression in H9c2 cells

Mi‑Hua Liu, Yuan Zhang, Xiao‑Long Lin, Jun He, Tian‑Ping Tan, Shao‑Jian Wu, Shan Yu, Li Chen, Yu‑Dan Chen, Hong‑Yun Fu, Cong Yuan, Jian Li
Pages: 5197-5202
Published online on: 02 July 2015

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Article

Lysophosphatidic acid increases the proliferation and migration of adipose‑derived stem cells via the generation of reactive oxygen species

Sangjin Kang, Juhee Han, Seung Yong Song, Won‑Serk Kim, Soyoung Shin, Ji Hye Kim, Hyosun Ahn, Jin‑Hyun Jeong, Sung‑Joo Hwang, Jong‑Hyuk Sung
Pages: 5203-5210
Published online on: 02 July 2015

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Article

Identification of genes associated with osteoarthritis by microarray analysis

Jianwei Sun, Bingshan Yan, Wangping Yin, Xinchao Zhang
Pages: 5211-5216
Published online on: 07 July 2015

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Article

Tyrosylprotein sulfotransferase 1 expression is negatively correlated with c‑Met and lymph node metastasis in human lung cancer

Zhibin Jiang, Jialiang Zhu, Yuchao Ma, Cao Hong, Sheng Xiao, Longyu Jin
Pages: 5217-5222
Published online on: 20 July 2015

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Article

Inhibitory effect of 2‑mercaptoethane sulfonate on the formation of Escherichia coli biofilms in vitro

Sheng Chen, Nianhai He, Jialin Yu, Luquan Li, Fengjun Sun, Ying Hu, Rui Deng, Shiming Zhong, Leilei Shen
Pages: 5223-5230
Published online on: 22 July 2015

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Article

Nuclear transcription factor CDX2 inhibits gastric cancer‑cell growth and reverses epithelial‑to‑mesenchymal transition in vitro and in vivo

Jian‑Feng Zhang, Li‑Shuai Qu, Xue‑Fen Qian, Bei‑Lei Xia, Zhen‑Biao Mao, Wei‑Chang Chen
Pages: 5231-5238
Published online on: 22 July 2015

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Article

Imbalance of tumor necrosis factor-α, interleukin-8 and interleukin-10 production evokes barrier dysfunction, severe abdominal symptoms and psychological disorders in patients with irritable bowel syndrome-associated diarrhea

Yanbo Zhen, Chuanlian Chu, Shiqing Zhou, Ming Qi, Ronghua Shu
Pages: 5239-5245
Published online on: 15 July 2015

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Article

Immunohistochemical analysis of phosphorylated mammalian target of rapamycin and its downstream signaling components in invasive breast cancer

Bin‑Lin Ma, Mei‑Hui Shan, Gang Sun, Guang‑Hui Ren, Chao Dong, Xuemei Yao, Mei Zhou
Pages: 5246-5254
Published online on: 03 July 2015

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Article

MicroRNA‑34a attenuates the proliferation, invasion and metastasis of gastric cancer cells via downregulation of MET

Bin Wei, Qiao Ying Huang, Shun Rong Huang, Wei Mai, Xiao Gang Zhong
Pages: 5255-5261
Published online on: 22 July 2015

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Article

Involvement of Kruppel-like factor 9 in bleomycin-induced pulmonary toxicity

Yue Gu, Yan‑Bing Wu, Li‑Hui Wang, Jia‑Ning Yin
Pages: 5262-5266
Published online on: 02 July 2015

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Article

Hypoxia promotes the proliferation of MC3T3-E1 cells via the hypoxia-inducible factor-1α signaling pathway

Lichao Wang, Buling Wu, Yu Zhang, Zhihui Tian
Pages: 5267-5273
Published online on: 03 July 2015

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Article

MicroRNA-215 is upregulated by treatment with Adriamycin and leads to the chemoresistance of hepatocellular carcinoma cells and tissues

Li Wang, Yan Ming Wang, Song Xu, Wei Guo Wang, Yang Chen, Jing Yu Mao, Bo Le Tian
Pages: 5274-5280
Published online on: 01 July 2015

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Article

Effects of two novel amino acid substitutions on the penicillin binding properties of the PBP5 C‑terminal from Enterococcus faecium

Chengjiang Zhou, Haiying Niu, Hui Yu, Lishe Zhou, Zhanli Wang
Pages: 5281-5285
Published online on: 08 July 2015

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Article

Inhibitory effect of zinc on the advanced glycation end product-induced apoptosis of mouse osteoblastic cells

Mingyue Xiong, Liqiang Liu, Zhenhui Liu, Hangfei Gao
Pages: 5286-5292
Published online on: 17 July 2015

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Article

Increased expression of Notch 1 in a rat liver transplantation model

Lihong Chen, Wubing He, Kaida Huang, Lin Zheng, Lingyun Gao, Jingfeng Liu, Aimin Huang
Pages: 5293-5297
Published online on: 02 July 2015

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Article

Practical assessment of the quantification of atherosclerotic lesions in apoE‑/‑ mice

Yan Lin, Liang Bai, Yulong Chen, Ninghong Zhu, Yanping Bai, Qianwei Li, Sihai Zhao, Jianglin Fan, Enqi Liu
Pages: 5298-5306
Published online on: 16 July 2015

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Article

House dust mite allergens mediate the activation of c‑kit in dendritic cells via Toll‑like receptor 2

Wei Wu, Chun‑Xia Wang, Hui Chen, Jing Zhou, Jin‑Zhao Zhang, Lin Gao, Hong‑Yan Zhou
Pages: 5307-5313
Published online on: 20 July 2015

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Article

Intracellular glutathione production, but not protein glycation, underlies the protective effects of captopril against 2‑deoxy‑D‑ribose‑induced β‑cell damage

Gwanpyo Koh, Eun‑Jin Yang, Ji Young Kim, Jonghoon Hyun, Soyeon Yoo, Sang Ah Lee
Pages: 5314-5320
Published online on: 06 July 2015

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Article

Yiqi Huaju formula, a Chinese herbal medicine, reduces arterial pressure in salt‑sensitive hypertension by inhibiting renin‑angiotensin system activation

Yan‑Ming He, Hong‑Jie Yang, Qiang Yang, Jin‑Gang Cui, Tian‑Zhan Wang, Yi Chen, Pei‑Wei Wang, Teng Zhang, Wen‑Jian Wang
Pages: 5321-5327
Published online on: 20 July 2015

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Article

Synergistic neuroprotective effect of microglial‑conditioned media treated with geniposide and ginsenoside Rg1 on hypoxia injured neurons

Jun Wang, Jincai Hou, Hongtao Lei, Jianhua Fu, Yanshu Pan, Jianxun Liu
Pages: 5328-5334
Published online on: 20 July 2015

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Article

LOX‑1 is implicated in oxidized low‑density lipoprotein‑induced oxidative stress of macrophages in atherosclerosis

Hui‑Yu Yang, Yun‑Fei Bian, Hua‑Ping Zhang, Fen Gao, Chuan‑Shi Xiao, Bin Liang, Jin Li, Na‑Na Zhang, Zhi‑Ming Yang
Pages: 5335-5341
Published online on: 08 July 2015

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Article

Oxidative damage to human parametrial ligament fibroblasts induced by mechanical stress

Shasha Hong, Li Hong, Debin Wu, Bingshu Li, Cheng Liu, Wenjun Guo, Jie Min, Ming Hu, Yang Zhao, Qing Yang
Pages: 5342-5348
Published online on: 23 July 2015

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Article

Carvacrol protects against spinal cord injury in rats via suppressing oxidative stress and the endothelial nitric oxide synthase pathway

Zhen‑Song Jiang, Zhi‑Chen Pu, Zhen‑Hai Hao
Pages: 5349-5354
Published online on: 06 July 2015

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Article

Chondrogenic differentiation of bone marrow‑derived stem cells cultured in the supernatant of elastic cartilage cells

Xiaodie Zhang, Ke Xue, Jia Zhou, Peng Xu, Huizhen Huang, Kai Liu
Pages: 5355-5360
Published online on: 22 July 2015

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Article

Networks of micrornas and genes in acute lymphoblastic leukemia

Yuhua Xie, Zhiwen Xu, Kunhao Wang, Ning Wang, Yunxiao Wang, Jiwei Bao
Pages: 5361-5368
Published online on: 23 July 2015

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Article

Oxymatrine suppresses proliferation and facilitates apoptosis of human ovarian cancer cells through upregulating microRNA‑29b and downregulating matrix metalloproteinase‑2 expression

Jingwei Li, Kailei Jiang, Fujie Zhao
Pages: 5369-5374
Published online on: 22 June 2015

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Article

Two faces of the estrogen metabolite 2-methoxyestradiol in vitro and in vivo

Ji‑Sun Lee, Yu‑Kyung Kim, Hyun Yang, Hee Young Kang, Changhwan Ahn, Eui‑Bae Jeung
Pages: 5375-5382
Published online on: 13 July 2015

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Article

Upregulation of microRNA‑335 and microRNA‑584 contributes to the pathogenesis of severe preeclampsia through downregulation of endothelial nitric oxide synthase

Feng Jiang, Jipeng Li, Guojun Wu, Zhuo Miao, Linshan Lu, Guoping Ren, Xiaohong Wang
Pages: 5383-5390
Published online on: 02 July 2015

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Article

Erythropoietin improves glucose metabolism and pancreatic β-cell damage in experimental diabetic rats

Li‑Na Chen, Qiang Sun, Shu‑Qing Liu, Hao Hu, Juan Lv, Wen‑Jun Ji, Meng Wang, Ming‑Xia Chen, Jun Zhou
Pages: 5391-5398
Published online on: 29 June 2015

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Article

MeCP2 controls hippocampal brain-derived neurotrophic factor expression via homeostatic interactions with microRNA‑132 in rats with depression

Meilei Su, Jun Hong, Yongzhi Zhao, Shuai Liu, Xiang Xue
Pages: 5399-5406
Published online on: 20 July 2015

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Article

Combinational treatment with microRNA‑133b and cetuximab has increased inhibitory effects on the growth and invasion of colorectal cancer cells by regulating EGFR

Jianyu Zhou, Lv Lv, Changwei Lin, Gui Hu, Yihang Guo, Meirong Wu, Buning Tian, Xiaorong Li
Pages: 5407-5414
Published online on: 06 July 2015

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Article

Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway

Zhiming Zhao, Chenggang Li, Hao Xi, Yuanxing Gao, Dabin Xu
Pages: 5415-5422
Published online on: 08 July 2015

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Article

Difference in protective effects of three structurally similar flavonoid glycosides from Hypericum ascyron against H2O2-induced injury in H9c2 cardiomyoblasts

Xiu‑Mei Li, Xue‑Gang Luo, Kun Li, Nan Wang, Er‑Bin Hua, Yao Zhang, Tong‑Cun Zhang
Pages: 5423-5428
Published online on: 15 July 2015

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Article

Association of genetic variants with dyslipidemia

Shintaro Abe, Fumitaka Tokoro, Reiko Matsuoka, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada
Pages: 5429-5436
Published online on: 16 July 2015

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Article

Anticancer activity of stoppin based on a novel peptide delivery system

Yan‑Fang Gao, Xue‑Ni Wei, Xiao‑Lei Ye, Guo‑Bin Weng, Yi‑Chen Chen, Ya‑Rong Zhao, Hui Ji
Pages: 5437-5442
Published online on: 02 July 2015

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Article

MicroRNA-7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6 Retraction in /10.3892/mmr.2021.12343

Jiashun Luo, Hui Li, Chunfang Zhang
Pages: 5443-5448
Published online on: 02 July 2015

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Article

Effects of X‑ray irradiation in combination with ascorbic acid on tumor control

Yoichiro Hosokawa, Satoru Monzen, Hironori Yoshino, Shingo Terashima, Manabu Nakano, Keisuke Toshima, Ryo Saga, Ikuo Kashiwakura
Pages: 5449-5454
Published online on: 22 July 2015

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Article

B7‑H3 promotes cell migration and invasion through the Jak2/Stat3/MMP9 signaling pathway in colorectal cancer

Fen Liu, Ting Zhang, Shitao Zou, Bo Jiang, Dong Hua
Pages: 5455-5460
Published online on: 07 July 2015

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Article

Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma

Hao Wu, Qiang Liu, Tao Cai, Yu‑Dan Chen, Zhi‑Fei Wang
Pages: 5461-5466
Published online on: 17 July 2015

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Article

Cross‑reactivity between group-5 and -21 mite allergens from Dermatophagoides farinae, Tyrophagus putrescentiae and Blomia tropicalis

Chung‑Ryul Kim, Kyoung Yong Jeong, Myung‑Hee Yi, Hyoung‑Pyo Kim, Ho‑Joon Shin, Tai‑Soon Yong
Pages: 5467-5474
Published online on: 20 July 2015

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Article

A functional polymorphism in the pre‑miR‑146a gene influences the prognosis of glioblastoma multiforme by interfering with the balance between Notch1 and Notch2

Rongyao Liu, Weihua Li, Chunming Wu
Pages: 5475-5481
Published online on: 09 July 2015

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Article

Overexpression of microRNA‑125a‑3p effectively inhibits the cell growth and invasion of lung cancer cells by regulating the mouse double minute 2 homolog/p53 signaling pathway

Shenglei Li, Xin Li, Huasi Zhao, Ming Gao, Feng Wang, Wencai Li
Pages: 5482-5486
Published online on: 03 July 2015

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Article

Decreased expression levels of Nurr1 are associated with chronic inflammation in patients with type 2 diabetes

Ying Xu, Qi Huang, Wenfang Zhang, Yaping Wang, Qingling Zeng, Chunyan He, Junli Xue, Jin Chen, Xuemei Hu, Yancheng Xu
Pages: 5487-5493
Published online on: 21 July 2015

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Article

Deglucose chikusetsusaponin IVa isolated from Rhizoma Panacis Majoris induces apoptosis in human HepG2 hepatoma cells

Xiaomei Song, Wei Wang, Xin Zhang, Yi Jiang, Xinjie Yang, Chong Deng, Zhenggang Yue, Zhishu Tang
Pages: 5494-5500
Published online on: 03 July 2015

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Article

Ascorbic acid inhibits TPA-induced HL‑60 cell differentiation by decreasing cellular H2O2 and ERK phosphorylation

Giou‑Teng Yiang, Jen‑Ni Chen, Tsai‑Kun Wu, Hsueh‑Fang Wang, Yu‑Ting Hung, Wei‑Jung Chang, Chinshuh Chen, Chyou‑Wei Wei, Yung‑Luen Yu
Pages: 5501-5507
Published online on: 20 July 2015

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Article

Molecular cloning and characterization of presenilin gene in Bombyx mori

Zeng‑Zhang Zheng, Meng‑Ling Chao, Zong‑Biao Fan, Yi‑Jiao Zhao, Hong‑Sheng Song
Pages: 5508-5516
Published online on: 02 July 2015

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Article

Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis Retraction in /10.3892/mmr.2022.12584

Dan Li, Zhitao Xiao, Gang Wang, Xianji Song
Pages: 5517-5523
Published online on: 01 July 2015

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Article

Heat shock protein 70 induction by glutamine increases the α‑synuclein degradation in SH‑SY5Y neuroblastoma cells

Jia Yang, Yanmei Zhang, Shigang Zhao, Zhelin Zhang, Xiuqing Tong, Fang Wei, Zuneng Lu
Pages: 5524-5530
Published online on: 02 July 2015

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Article

Increased frequencies of memory and activated B cells and follicular helper T cells are positively associated with high levels of activation‑induced cytidine deaminase in patients with immunoglobulin A nephropathy

Ying Sun, Zhihong Liu, Ying Liu, Xia Li
Pages: 5531-5537
Published online on: 09 July 2015

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Article

HAND2‑mediated proteolysis negatively regulates the function of estrogen receptor α

Tomohiko Fukuda, Akira Shirane, Osamu Wada‑Hiraike, Katsutoshi Oda, Michihiro Tanikawa, Ayako Sakuabashi, Mana Hirano, Houju Fu, Yoshihiro Morita, Yuichiro Miyamoto, Kanako Inaba, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
Pages: 5538-5544
Published online on: 09 July 2015

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Article

Stimulation of RAW264.7 macrophages by sulfated Escherichia coli K5 capsular polysaccharide in vitro

Liping Teng, Haitian Fu, Min Wang, Chao Deng, Jinghua Chen
Pages: 5545-5553
Published online on: 16 July 2015

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Article

MicroRNA-203 inhibits the malignant progression of neuroblastoma by targeting Sam68

Dongju Zhao, Yunjiao Tian, Peiling Li, Limin Wang, Aiju Xiao, Mingqiu Zhang, Taixin Shi
Pages: 5554-5560
Published online on: 01 July 2015

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Article

Effects of Wnt/β‑catenin signaling on bisphenol A exposure in male mouse reproductive cells

Zhiqi Fang, Xiaoli Liu, Xiaosi Yang, Xianbin Song, Xiaoyu Chen
Pages: 5561-5567
Published online on: 02 July 2015

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Article

1‑O‑acetylbritannilactone combined with gemcitabine elicits growth inhibition and apoptosis in A549 human non‑small cell lung cancer cells

Feng Wang, Hong Li, Jian‑Ou Qiao
Pages: 5568-5572
Published online on: 03 July 2015

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Article

Transforming growth factor‑β1 induces type II collagen and aggrecan expression via activation of extracellular signal‑regulated kinase 1/2 and Smad2/3 signaling pathways

Yanhui Zhu, Hairong Tao, Chen Jin, Yonzhang Liu, Xiongwei Lu, Xiaopeng Hu, Xiang Wang
Pages: 5573-5579
Published online on: 09 July 2015

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Article

Berberine inhibits tumor necrosis factor‑α‑induced expression of inflammatory molecules and activation of nuclear factor‑κB via the activation of AMPK in vascular endothelial cells

Su‑Jian Liu, Cai‑Xia Yin, Ming‑Chao Ding, Yi‑Zhong Wang, Hong Wang
Pages: 5580-5586
Published online on: 08 July 2015

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Article Open Access

Roles of microRNA-146a and microRNA-181b in regulating the secretion of tumor necrosis factor-α and interleukin-1β in silicon dioxide-induced NR8383 rat macrophages

Yang Zhang, Faxuan Wang, Yajia Lan, Dinglun Zhou, Xiaohui Ren, Liqiang Zhao, Qin Zhang
Pages: 5587-5593
Published online on: 16 July 2015

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Article

Human recombinant endostatin Endostar attenuates hepatic sinusoidal endothelial cell capillarization in CCl4‑induced fibrosis in mice

Qi You, Ling‑Jian Kong, Feng‑Dong Li, Hang‑Yu Wang, Dian‑Gang Liu, Feng‑Hua Pei, Ji‑Tao Song, Jun Xu, Jing Chen
Pages: 5594-5600
Published online on: 20 July 2015

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Retraction Open Access

[Retracted] Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways

Gongli Yang, Feng Ma, Muxiao Zhong, Lin Fang, Yao Peng, Xiaoming Xin, Jietao Zhong, Wei Zhu, Yali Zhang
Pages: 5601-5601
Published online on: 22 July 2015

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Correction Open Access

[Erratum] Effects of glucose-dependent insulinotropic polypeptide receptor knockout and a high-fat diet on cognitive function and hippocampal gene expression in mice

Rachael Lennox, R. Charlotte Moffett, David W. Porter, Nigel Irwin, Victor A. Gault, Peter R. Flatt
Pages: 5602-5602
Published online on: 15 July 2015

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Review

Long non-coding RNA HOTAIR: A novel oncogene (Review)

Xin Yu, Zheng Li
Pages: 5611-5618
Published online on: 31 July 2015

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Article Open Access

Lentivirus‑delivered nemo‑like kinase small interfering RNA inhibits laryngeal cancer cell proliferation in vitro

Jun Tai, Yuansheng Rao, Jugao Fang, Zhigang Huang, Zhenkun Yu, Xiaohong Chen, Weiguo Zhou, Xiao Xiao, Ting Long, Yang Han, Qiaoyin Liu, Aidong Li, Xin Ni
Pages: 5619-5624
Published online on: 06 August 2015

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Article Open Access

Expression pattern of aquaporins in patients with primary nephrotic syndrome with edema

Yu Wang, Jimei Bu, Qing Zhang, Kai Chen, Jihong Zhang, Xiaorong Bao
Pages: 5625-5632
Published online on: 11 August 2015

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Article Open Access

Evaluation of reference gene suitability for quantitative expression analysis by quantitative polymerase chain reaction in the mandibular condyle of sheep

Xin Jiang, Yang Xue, Hongzhi Zhou, Shouhong Li, Zongmin Zhang, Rui Hou, Yuxiang Ding, Kaijin Hu
Pages: 5633-5640
Published online on: 28 July 2015

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Article Open Access

GSK1838705A, an IGF-1R inhibitor, inhibits glioma cell proliferation and suppresses tumor growth in vivo

Xiang Zhou, Fazheng Shen, Pengju Ma, Hongyan Hui, Sujuan Pei, Ming Chen, Zhongwei Wang, Wenke Zhou, Baozhe Jin
Pages: 5641-5646
Published online on: 28 July 2015

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Article Open Access

Analysis of the differential expression of circulating microRNAs during the progression of hepatic fibrosis in patients with chronic hepatitis B virus infection

Qingqing Zhang, Mingyi Xu, Ying Qu, Zhenghong Li, Qidi Zhang, Xiaobo Cai, Lungen Lu
Pages: 5647-5654
Published online on: 12 August 2015

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Article Open Access

1q21.1 microduplication in a patient with mental impairment and congenital heart defect

Guowen Sun, Zhiping Tan, Liangliang Fan, Jian Wang, Yifeng Yang, Weizhi Zhang
Pages: 5655-5658
Published online on: 31 July 2015

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Case Report Open Access

A duplication upstream of SOX9 was not positively correlated with the SRY‑negative 46,XX testicular disorder of sex development: A case report and literature review

Xin‑Yi Xia, Cui Zhang, Tian‑Fu Li, Qiu‑Yue Wu, Na Li, Wei‑Wei Li, Ying‑Xia Cui, Xiao‑Jun Li, Yi‑Chao Shi
Pages: 5659-5664
Published online on: 10 August 2015

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Article Open Access

Endosialin‑expressing bone sarcoma stem‑like cells are highly tumor‑initiating and invasive

Dong‑Xiu Sun, Guang‑Jun Liao, Ke‑Gui Liu, Han Jian
Pages: 5665-5670
Published online on: 12 August 2015

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Article Open Access

Synergistic effect of a tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 co‑expression vector on the proliferation of rat vascular smooth muscle cells

Pengli Zhu, Huizhen Yu, Shujie Huang, Hong Xiang, Feng Li, Weiping Zheng
Pages: 5671-5678
Published online on: 07 August 2015

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Article Open Access

Fatsioside A‑induced apoptotic death of HepG2 cells requires activation of AMP‑activated protein kinase

Yu‑Shan Zheng, Jian‑You Zhang, Dong‑Hui Zhang
Pages: 5679-5684
Published online on: 06 August 2015

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Article Open Access

Association between xanthine dehydrogenase tag single nucleotide polymorphisms and essential hypertension

Baogang Wu, Ying Hao, Jin Shi, Ning Geng, Tiejun Li, Yanli Chen, Zhaoqing Sun, Liqiang Zheng, Hong Li, Naijing Li, Xingang Zhang, Yingxian Sun
Pages: 5685-5690
Published online on: 29 July 2015

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Article Open Access

Lentiviral-mediated growth-associated protein-43 modification of bone marrow mesenchymal stem cells improves traumatic optic neuropathy in rats

Qi Zhu, Zaoxia Liu, Chenguang Wang, Lili Nie, Yuxi He, Yan Zhang, Xin Liu, Guanfang Su
Pages: 5691-5700
Published online on: 28 July 2015

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Article Open Access

An in vitro investigation into the role of bone marrow‑derived mesenchymal stem cells in the control of disc degeneration

Jinquan Hu, Guoying Deng, Ye Tian, Yingyan Pu, Peng Cao, Wen Yuan
Pages: 5701-5708
Published online on: 29 July 2015

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Article Open Access

MicroRNA‑34a induces apoptosis in PC12 cells by reducing B‑cell lymphoma 2 and sirtuin‑1 expression

Qiang Lin, Yurong Mao, Yunlin Song, Dongfeng Huang
Pages: 5709-5714
Published online on: 05 August 2015

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Article Open Access

MicroRNA‑205 promotes the tumorigenesis of nasopharyngeal carcinoma through targeting tumor protein p53-inducible nuclear protein 1

Guohui Nie, Hongfang Duan, Xiaoqing Li, Zhendong Yu, Liang Luo, Ruijing Lu, Ziliang Ji, Wei Zhang
Pages: 5715-5722
Published online on: 05 August 2015

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Article Open Access

Prostaglandin E1 protects bone marrow‑derived mesenchymal stem cells against serum deprivation‑induced apoptosis

Kuan Zeng, Bao Ping Deng, Hui‑Qi Jiang, Meng Wang, Ping Hua, Hong‑Wu Zhang, Yu‑Bin Deng, Yan‑Qi Yang
Pages: 5723-5729
Published online on: 05 August 2015

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Article Open Access

N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Pages: 5730-5736
Published online on: 03 August 2015

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Article Open Access

Structural analysis of a type 1 ribosome inactivating protein reveals multiple L‑asparagine‑N‑acetyl‑D‑glucosamine monosaccharide modifications: Implications for cytotoxicity

Tanis Hogg, Jameson T. Mendel, Jonathan L. Lavezo
Pages: 5737-5745
Published online on: 29 July 2015

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Article Open Access

Effects of rotigaptide (ZP123) on connexin43 remodeling in canine ventricular fibrillation Corrigendum in /mmr/12/6/8327

Guo-Ying Su, Jing Wang, Zhen-Xing Xu, Xiao-Jun Qiao, Jing-Quan Zhong, Yun Zhang
Pages: 5746-5752
Published online on: 06 August 2015

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Article Open Access

Expression of microRNA‑26b and identification of its target gene EphA2 in pituitary tissues in Yanbian cattle

Bao Yuan, Wang‑Yang Yu, Li‑Sheng Dai, Yan Gao, Yu Ding, Xian‑Feng Yu, Jian Chen, Jia‑Bao Zhang
Pages: 5753-5761
Published online on: 06 August 2015

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Article Open Access

Essential oil of Artemisia vestita exhibits potent in vitro and in vivo antibacterial activity: Investigation of the effect of oil on biofilm formation, leakage of potassium ions and survival curve measurement

Chang Yang, Dong‑Hui Hu, Yan Feng
Pages: 5762-5770
Published online on: 11 August 2015

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Article Open Access

Low expression of DLC1 is predictive of poor therapeutic efficiency of fluoropyrimidine and oxaliplatin as adjuvant chemotherapy in gastric cancer

Yuqi Su, Li Lin, Jingwen Zhang, Yaqi Jiang, Changqie Pan, Li Sun, Jiangman Duan, Wangjun Liao
Pages: 5771-5779
Published online on: 03 August 2015

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Article Open Access

MicroRNA‑19a mediates gastric carcinoma cell proliferation through the activation of nuclear factor‑κB

Fan Yang, Hongjian Wang, Zhenyu Jiang, Anxiang Hu, Lisha Chu, Yiling Sun, Junqing Han
Pages: 5780-5786
Published online on: 29 July 2015

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Article Open Access

Molecular docking to explore the possible binding mode of potential inhibitors of thioredoxin glutathione reductase

Jingwei Huang, Weijuan Hua, Jiahuang Li, Zichun Hua
Pages: 5787-5795
Published online on: 27 July 2015

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Article Open Access

Autophagy inhibition enhances isorhamnetin‑induced mitochondria‑dependent apoptosis in non‑small cell lung cancer cells

Yushu Ruan, Ke Hu, Hongbo Chen
Pages: 5796-5806
Published online on: 29 July 2015

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Article Open Access

Histopathology of melanosis coli and determination of its associated genes by comparative analysis of expression microarrays

Xiao‑Αn Li, Yan Zhou, Shu‑Χian Zhou, Hai‑Rong Liu, Jin‑Mei Xu, Long Gao, Xian‑Jing Yu, Xiao‑Hui Li
Pages: 5807-5815
Published online on: 27 July 2015

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Article Open Access

Ponicidin suppresses HT29 cell growth via the induction of G1 cell cycle arrest and apoptosis

Jie Du, Chunyou Chen, Yiqun Sun, Lin Zheng, Wanchen Wang
Pages: 5816-5820
Published online on: 29 July 2015

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Article Open Access

Activated farnesoid X receptor attenuates apoptosis and liver injury in autoimmune hepatitis

Fan Lian, Yu Wang, Youjun Xiao, Xiwen Wu, Hanshi Xu, Liuqin Liang, Xiuyan Yang
Pages: 5821-5827
Published online on: 31 July 2015

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Article Open Access

Silica promotes the transdifferentiation of rat circulating fibrocytes in vitro

Wu Yao, Suna Liu, Ju Li, Changfu Hao
Pages: 5828-5836
Published online on: 11 August 2015

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Article Open Access

Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin inhibits methylglyoxal‑mediated glycation of proteins

Eunjin Sohn, Junghyun Kim, Chan Sik Kim, Kyuhyung Jo, Jin Sook Kim
Pages: 5837-5845
Published online on: 11 August 2015

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Article Open Access

Polyphenolic composition of grape stem extracts affects antioxidant activity in endothelial and muscle cells

Nikolaos Goutzourelas, Dimitrios Stagos, Ypatios Spanidis, Maria Liosi, Anna Apostolou, Alexandros Priftis, Serko Haroutounian, Demetrios A. Spandidos, Aristidis M. Tsatsakis, Demetrios Kouretas
Pages: 5846-5856
Published online on: 12 August 2015

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Article

Rose myrtle (Rhodomyrtus tomentosa) extract and its component, piceatannol, enhance the activity of DNA polymerase and suppress the inflammatory response elicited by UVB‑induced DNA damage in skin cells

Sawako Shiratake, Tatsuo Nakahara, Hiroyasu Iwahashi, Takefumi Onodera, Yoshiyuki Mizushina
Pages: 5857-5864
Published online on: 30 July 2015

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Article

Emodin inhibits angiogenesis in pancreatic cancer by regulating the transforming growth factor-β/drosophila mothers against decapentaplegic pathway and angiogenesis-associated microRNAs

Sheng‑Zhang Lin, Jin‑Bo Xu, Xu Ji, Hui Chen, Hong-Tao Xu, Ping Hu, Liang Chen, Jing‑Qiang Guo, Min‑Yuan Chen, Dian Lu, Zhao‑Hong Wang, Hong‑Fei Tong
Pages: 5865-5871
Published online on: 31 July 2015

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Article

Roles of heat shock factor 1 in isoproterenol‑induced myocardial fibrosis in mice

Yong Xie, Lihua Zhang, Bin Zhang, Li Fang
Pages: 5872-5878
Published online on: 30 July 2015

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Article

Optimal compressive force accelerates osteoclastogenesis in RAW264.7 cells

Takako Hayakawa, Yoshitaka Yoshimura, Takashi Kikuiri, Mino Matsuno, Tomokazu Hasegawa, Kumu Fukushima, Kenjiro Shibata, Yoshiaki Deyama, Kuniaki Suzuki, Junichiro Iida
Pages: 5879-5885
Published online on: 29 July 2015

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Article

A genome-wide study of DNA methylation modified by epigallocatechin-3-gallate in the CAL-27 cell line

Li‑Li Chen, Wen‑Fei Han, Ying Geng, Jian‑Sheng Su
Pages: 5886-5890
Published online on: 27 July 2015

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Article

Gremlin 2 inhibits adipocyte differentiation through activation of Wnt/β-catenin signaling

Qing Wu, Shi-Guo Tang, Zhong‑Ming Yuan
Pages: 5891-5896
Published online on: 27 July 2015

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Article

Tectonic 1 accelerates gastric cancer cell proliferation and cell cycle progression in vitro

Xinbao Wang, Qiming Yu, Yingli Zhang, Zhiqiang Ling, Pengfei Yu
Pages: 5897-5902
Published online on: 05 August 2015

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Article

Simvastatin promotes alveolar epithelial cell proliferation and attenuates cigarette smoke‑induced emphysema in rats

Shuyue Xia, Jian Kang, Yanduo Jiang, Desheng Huang, Shi Wang, Baosen Pang
Pages: 5903-5910
Published online on: 03 August 2015

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Inactivation of INK4a and ARF induces myocardial proliferation and improves cardiac repair following ischemia‑reperfusion

Songtao An, Yan Chen, Chuanyu Gao, Bingyu Qin, Xianhui Du, Fanmin Meng, Yanyan Qi
Pages: 5911-5916
Published online on: 29 July 2015

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Article

Epirubicin inhibits growth and alters the malignant phenotype of the U‑87 glioma cell line

Xiao‑Feng Wang, Zhe‑Feng Zhao, Ming‑Hui Chen, Qing‑Hua Yuan, Yong‑Li Li, Chuan‑Lu Jiang
Pages: 5917-5923
Published online on: 12 August 2015

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Article

Combination of L-gossypol and low-concentration doxorubicin induces apoptosis in human synovial sarcoma cells

Xilin Baoleri, Chao Dong, Yang Zhou, Zhaojun Zhang, Xueliang Lu, Pengming Xie, Yongqi Li
Pages: 5924-5932
Published online on: 28 July 2015

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Article

Effect of transplanted adipose‑derived stem cells in mice exhibiting idiopathic pulmonary fibrosis

Hongbin Jiang, Jun Zhang, Zhemin Zhang, Shengxiang Ren, Chuansen Zhang
Pages: 5933-5938
Published online on: 05 August 2015

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Article

Colchicine induces apoptosis in HT‑29 human colon cancer cells via the AKT and c-Jun N-terminal kinase signaling pathways

Zhen Huang, Ye Xu, Wei Peng
Pages: 5939-5944
Published online on: 12 August 2015

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Article

Phenethyl isothiocyanate enhances adriamycin‑induced apoptosis in osteosarcoma cells

Qie Fan, Xinli Zhan, Zengming Xiao, Chong Liu
Pages: 5945-5950
Published online on: 05 August 2015

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Article

Effect of CoCl2 on fracture repair in a rat model of bone fracture

Jiang Huang, Liming Liu, Mingli Feng, Shuai An, Meng Zhou, Zheng Li, Jiajian Qi, Huiliang Shen
Pages: 5951-5956
Published online on: 27 July 2015

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Article

Gua Lou Gui Zhi decoction attenuates post‑stroke spasticity via the modulation of GABAB receptors

Xiaoqin Zhu, Haixia Hu, Zuanfang Li, Ruhui Lin, Jingjie Mao, Lidian Chen
Pages: 5957-5962
Published online on: 11 August 2015

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Article

Determination of ABO blood group genotypes using the real‑time loop‑mediated isothermal amplification method

Chao Zhang, Juanli Zhu, Jiangcun Yang, Yinsheng Wan, Ting Ma, Yali Cui
Pages: 5963-5966
Published online on: 29 July 2015

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Article

Catabolite control protein A has an important role in the metabolic regulation of Streptococcus suis type 2 according to iTRAQ-based quantitative proteomic analysis

Xulong Lang, Zhonghai Wan, Ying Pan, Zhaoyang Bu, Xiuran Wang, Xiaoxu Wang, Xue Ji, Lingwei Zhu, Jiayu Wan, Yang Sun, Xinglong Wang
Pages: 5967-5972
Published online on: 11 August 2015

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Article

Zinc deficiency during in vitro maturation of porcine oocytes causes meiotic block and developmental failure

Yubyeol Jeon, Junchul David Yoon, Lian Cai, Seon‑Ung Hwang, Eunhye Kim, Zhong Zheng, Euibae Jeung, Eunsong Lee, Sang‑Hwan Hyun
Pages: 5973-5982
Published online on: 27 July 2015

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Article

Molecular screening of the LPCAT1 gene in patients with retinitis pigmentosa without defined mutations in known retinitis pigmentosa genes

Juan Wu, Hong‑Ting Wang, Xiu‑Feng Huang, Xin‑Lan Lei, Qin‑Kang Lu, Zi‑Bing Jin
Pages: 5983-5988
Published online on: 10 August 2015

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Article

Characterization of fluorescent NBD‑cholesterol efflux in thp‑1‑derived macrophages

Wei Song, Wei Wang, Yu Wang, Liyang Dou, Lianfeng Chen, Xiaowei Yan
Pages: 5989-5996
Published online on: 30 July 2015

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Article

High‑mobility group box 1 has a prognostic role and contributes to epithelial mesenchymal transition in human hepatocellular carcinoma

Zhikui Liu, Changwei Dou, Yufeng Wang, Yuli Jia, Qing Li, Xin Zheng, Yingmin Yao, Qingguang Liu, Tao Song
Pages: 5997-6004
Published online on: 05 August 2015

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Article

Elastic large muscular vessel wall engineered with bone marrow‑derived cells under pulsatile stimulation in a bioreactor

Zhi Cheng Xu, Qun Zhang, Hong Li
Pages: 6005-6012
Published online on: 29 July 2015

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Article

Inhibition of microRNA‑155 relieves sepsis‑induced liver injury through inactivating the JAK/STAT pathway

Xin Lv, Yucai Zhang, Yun Cui, Yuqian Ren, Rui Li, Qunfang Rong
Pages: 6013-6018
Published online on: 05 August 2015

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Article

Distribution and effect of steroidal saponin derivative WRC3 in B16 melanoma cells

Zeliang Wei, Yuyan Liang, Limei Ma, Ke Li, Hai Niu, Wen Huang
Pages: 6019-6024
Published online on: 12 August 2015

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Article

Expression of protein kinase C isoforms in cultured human tenon's capsule fibroblast cells

Ping Ma, Qianying Gao, Zhichong Wang, Keming Yu
Pages: 6025-6030
Published online on: 10 August 2015

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Article

Epigallocatechin‑3‑gallate inhibits the invasion of salivary adenoid cystic carcinoma cells by reversing the hypermethylation status of the RECK gene

Xiao‑Qing Zhou, Xiao‑Nan Xu, Lei Li, Jian‑Jun Ma, En‑Ming Zhen, Cheng‑Bing Han
Pages: 6031-6036
Published online on: 11 August 2015

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K604, a specific acyl‑CoA:cholesterol acyltransferase 1 inhibitor, suppresses proliferation of U251‑MG glioblastoma cells

Takuji Ohmoto, Kazuchika Nishitsuji, Nobuyuki Yoshitani, Makoto Mizuguchi, Yuto Yanagisawa, Hiroyuki Saito, Naomi Sakashita
Pages: 6037-6042
Published online on: 07 August 2015

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Inhibition of microRNA‑30a prevents puromycin aminonucleoside‑induced podocytic apoptosis by upregulating the glucocorticoid receptor α

Hua Xie, Hong‑Li Lin, Nan Wang, Yan‑Ling Sun, Yu Kan, Hui Guo, Ji‑Lin Chen, Ming Fang
Pages: 6043-6052
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SHSST‑cyclodextrin complex inhibits TGF‑β/Smad3/CTGF to a greater extent than silymarin in a rat model of carbon tetrachloride‑induced liver injury

Cheng‑Hsun Yang, Wei‑Jen Ting, Chia‑Yao Shen, His‑Hsien Hsu, Yueh‑Min Lin, Sheng-Huang Chang, Fuu‑Jen Tsai, Viswanadha Vijaya Padma, Chih‑Yang Huang, Yuhsin Tsai
Pages: 6053-6059
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Article

Small nuclear ribonucleoprotein associated polypeptide N accelerates cell proliferation in pancreatic adenocarcinoma

Jin Ma, Zhuo Zhang, Jiancheng Wang
Pages: 6060-6064
Published online on: 11 August 2015

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Article

Effect of transcatheter arterial chemoembolization on cellular immune function and regulatory T cells in patients with hepatocellular carcinoma

Juan Liao, Jiangwei Xiao, Yunfeng Zhou, Zilin Liu, Chunhui Wang
Pages: 6065-6071
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DAL‑1/4.1B contributes to epithelial‑mesenchymal transition via regulation of transforming growth factor‑β in lung cancer cell lines

Feng Yu, Hua Yang, Zhanmin Zhang, Zhijun Wang, Jianping Xiong
Pages: 6072-6078
Published online on: 12 August 2015

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Activation of Toll-like receptor 7 inhibits the proliferation and migration, and induces the apoptosis of pancreatic cancer cells

Bing‑Bing Zou, Fang Wang, Lei Li, Feng‑Wei Cheng, Rui Jin, Xin Luo, Li‑Xin Zhu, Xiaoping Geng, Sheng‑Quan Zhang
Pages: 6079-6085
Published online on: 28 July 2015

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Vitamin C attenuates the toxic effect of aristolochic acid on renal tubular cells via decreasing oxidative stress‑mediated cell death pathways

Tsai‑Kun Wu, Chyou‑Wei Wei, Ying‑Ru Pan, Shur‑Hueih Cherng, Wei‑Jung Chang, Hsueh‑Fang Wang, Yung‑Luen Yu
Pages: 6086-6092
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Effect of thymosin α1 on the phenotypic and functional maturation of dendritic cells from children with acute lymphoblastic leukemia

Xuerong Li, Xiaodan Liu, Yanxia Zhao, Ren Zhong, Aiqin Song, Lirong Sun
Pages: 6093-6097
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Association between liver X receptor‑α and neuron‑derived orphan nuclear receptor‑1 in Kupffer cells of C57BL/6 mice during inflammation

Kun He, Zhuo‑Ya Dai, Pei‑Zhi Li, Xi‑Wen Zhu, Jian‑Ping Gong
Pages: 6098-6104
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Clinical correlation of peripheral CD4+‑cell sub‑sets, their imbalance and Parkinson's disease

Yuhua Chen, Benquan Qi, Wenfang Xu, Bo Ma, Li Li, Qiming Chen, Weidong Qian, Xiaolin Liu, Hongdang Qu
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Fenofibrate suppresses cellular metabolic memory of high glucose in diabetic retinopathy via a sirtuin 1-dependent signalling pathway

Shuzhi Zhao, Jun Li, Na Wang, Bingqing Zheng, Tao Li, Qing Gu, Xun Xu, Zhi Zheng
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Probiotics modify human intestinal mucosa-associated microbiota in patients with colorectal cancer

Zhiguang Gao, Bomin Guo, Renyuan Gao, Qingchao Zhu, Wen Wu, Huanlong Qin
Pages: 6119-6127
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Two‑gene mutation in a single patient: Biochemical and functional analysis for a correct interpretation of exome results

Anna Monica Bianco, Flavio Faletra, Diego Vozzi, Martina Girardelli, Alessandra Knowles, Alberto Tommasini, Giorgio Zauli, Annalisa Marcuzzi
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Resveratrol inhibits oligomeric Aβ‑induced microglial activation via NADPH oxidase

Yao Yao, Juan Li, Yang Niu, Jian‑Qiang Yu, Ling Yan, Zhen‑Hua Miao, Xun‑Xia Zhao, Yuan‑Jie Li, Wan‑Xia Yao, Ping Zheng, Wei‑Qi Li
Pages: 6133-6139
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Hepatoma‑derived growth factor‑2 is highly expressed during development and in spinal cord injury

Zerui Zhuang, Guolong Mei, Weidong Liu, Yuchun Chen, Jican Zeng, Wei Zhang, Guanfeng Yao, Xinjia Wang
Pages: 6140-6144
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Pravastatin inhibits fibrinogen‑ and FDP‑induced inflammatory response via reducing the production of IL‑6, TNF‑α and iNOS in vascular smooth muscle cells

Peipei Lu, Juntian Liu, Xiaoming Pang
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MEN1 c.825‑1G>A mutation in a family with multiple endocrine neoplasia type 1: A case report

Zhiwei Ning, Ou Wang, Xunwu Meng, Xiaoping Xing, Weibo Xia, Yan Jiang, Mei Li, Yuan Xu
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Effect of quantum dots on the biological behavior of the EJ human bladder urothelial carcinoma cell line

Run Yuan, Wei‑Min Yu, Fan Cheng, Xiao‑Bin Zhang, Yuan Ruan, Zhi‑Xiu Cao, Stéphane Larré
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Upregulation of the gene expression of CLOCK is correlated with hypoxia‑inducible factor 1α in advanced varicose lesions

Xiao Tang, Daqiao Guo, Changpo Lin, Zhenyu Shi, Ruizhe Qian, Weiguo Fu, Jianjun Liu, Xu Li, Longhua Fan
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Effect of FTY720-phosphate on the expression of inflammation-associated molecules in astrocytes in vitro

Stefanie Janssen, Caroline Schlegel, Viktoria Gudi, Chittappen Kandiyil Prajeeth, Thomas Skripuletz, Corinna Trebst, Martin Stangel
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MicroRNA‑29a inhibits mesenchymal stem cell viability and proliferation by targeting Roundabout 1

Yudong Zhang, Shenghua Zhou
Pages: 6178-6184
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MicroRNA‑210 is upregulated by hypoxia-inducible factor‑1α in the stromal cells of giant cell tumors of bone

Shibing Guo, Rui Bai, Wanlin Liu, Aiqing Zhao, Zhenqun Zhao, Yuxin Wang, Yong Wang, Wei Zhao, Wenxuan Wang
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MicroRNA-145 inhibits migration and invasion via inhibition of fascin 1 protein expression in non-small-cell lung cancer cells Retraction in /10.3892/mmr.2021.12365

Yingying Zhang, Xucheng Yang, Haijun Wu, Weibin Zhou, Zhenzhen Liu
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An insertion/deletion polymorphism at the microRNA-122 binding site in the interleukin-1α 3'-untranslated region is associated with a risk for osteoarthritis

Fan Yang, Anfeng Hu, Dewei Zhao, Lin Guo, Lei Yang, Benjie Wang, Fengde Tian, Baoyi Liu, Shibo Huang, Hui Xie
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Raloxifene neutralizes the adverse effects of glutamate on cultured neurons by regulation of calcium oscillations

Xiangyu Zhou, Zhendong Yang, Li Han, Xiaoyong Li, Meina Feng, Teng Zhang, Hongbin Luo, Liping Zhu, Jiwei Zhang, Qi Zhang, Qinghua Hu
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Hochu‑ekki‑to (Bu‑zhong‑yi‑qi‑tang), a herbal medicine, enhances cisplatin‑induced apoptosis in HeLa cells

Tetsuo Sato, Kazuko Kita, Chihomi Sato, Atsushi Kaneda
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Peroxisome proliferator‑activated receptor γ prevents the production of NOD-like receptor family, pyrin domain containing 3 inflammasome and interleukin 1β in HK‑2 renal tubular epithelial cells stimulated by monosodium urate crystals

Wei Hong, Shasha Hu, Jianan Zou, Jing Xiao, Xiaoli Zhang, Chensheng Fu, Xinhui Feng, Zhibin Ye
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Activation of protease‑activated receptor‑2 is associated with increased expression of inflammatory factors in the adipose tissues of obese mice

Mengmeng Li, Xiaoming Yang, Yadong Zhang, Liang Chen, Hanyu Lu, Xiaobo Li, Lianhua Yin, Xiuling Zhi
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MicroRNA‑133a and microRNA‑326 co‑contribute to hepatocellular carcinoma 5‑fluorouracil and cisplatin sensitivity by directly targeting B‑cell lymphoma‑extra large

Jin Ma, Ting Wang, Rui Guo, Xiaoyan Yang, Jie Yin, Jia Yu, Qiong Xiang, Xia Pan, Xuyu Zu, Cuiying Peng, Huifang Tang, Xiaoyong Lei
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Proinflammatory effects of the hemagglutinin protein of the avian influenza A (H7N9) virus and microRNA‑mediated homeostasis response in THP‑1 cells

Shaobo Zhang, Dayong Gu, Xiaoxi Ouyang, Weidong Xie
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MicroRNA‑128a, BMI1 polycomb ring finger oncogene, and reactive oxygen species inhibit the growth of U‑87 MG glioblastoma cells following exposure to X‑ray radiation

Lan Ye, Guanying Yu, Cuihong Wang, Bin Du, Dianshui Sun, Junli Liu, Tonggang Qi, Xiaoming Yu, Wei Wei, Jian Cheng, Yuhua Jiang
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Peroxisome proliferator‑activated receptor‑γ inhibits pancreatic cancer cell invasion and metastasis via regulating MMP‑2 expression through PTEN

Yue Li, Da‑Wei Zhang, Dian‑Qiang Lin, Liang‑Qi Cao
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miR‑214 promotes osteosarcoma tumor growth and metastasis by decreasing the expression of PTEN

Chun‑Jie Liu, Kun‑Lun Yu, Guo‑Li Liu, De‑Hu Tian
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Mutation analysis of CACNA1S and SCN4A in patients with hypokalemic periodic paralysis

Xiao‑Ying Wang, Bing‑Wen Ren, Zeng‑Hua Yong, Hong‑Yan Xu, Qiu‑Xia Fu, He‑Bin Yao
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Promoter methylation, mRNA expression of goat tumor‑associated genes and mRNA expression of DNA methyltransferase in enzootic nasal tumors

Zifang Quan, Ni Ye, Zhongxiang Hao, Caifang Wen, Hong Liao, Manli Zhang, Lu Luo, Sanjie Cao, Xintian Wen, Rui Wu, Qigui Yan
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MicroRNA‑214 promotes proliferation and inhibits apoptosis via targeting Bax in nasopharyngeal carcinoma cells Retraction in /10.3892/mmr.2021.12334

Jian He, Yaoyun Tang, Yongquan Tian
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Cytotoxic and apoptogenic effects of Strobilanthes crispa Blume extracts on nasopharyngeal cancer cells

Rhun Yian Koh, Yi Chi Sim, Hwee Jin Toh, Liang Kuan Liam, Rachael Sze Lynn Ong, Mei Yeng Yew, Yee Lian Tiong, Anna Pick Kiong Ling, Soi Moi Chye, Khuen Yen Ng
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Momordica cochinchinensis Spreng. seed extract suppresses breast cancer growth by inducing cell cycle arrest and apoptosis

Lei Zheng, Yanmin Zhang, Yanping Liu, Xiaoyan Ou Yang, Yingzhuan Zhan
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Immunological characterization and verification of recombinant streptococcal protein G

Hucheng Zhang, Weifeng Liang, Haitao Fan, Jun Yang, Guowei Yang, Xiaojie Wang, Liang Chen, Tao Liang
Pages: 6311-6315
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Article

Small interfering RNA-induced silencing of galectin-3 inhibits the malignant phenotypes of osteosarcoma in vitro Retraction in /10.3892/mmr.2021.12309

Pengfei Lei, Hongbo He, Yihe Hu, Zhan Liao
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Nuclear respiratory factor‑2α and adenosine triphosphate synapses in rat primary cortical neuron cultures: The key role of adenosine monophosphate‑activated protein kinase

Xiang Chen, Xiao Zhao, Maonian Zhang, Shihui Wei
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A comparative study of acellular nerve xenografts and allografts in repairing rat facial nerve defects

Haitao Huang, Hongxi Xiao, Huawei Liu, Yu Niu, Rongzeng Yan, Min Hu
Pages: 6330-6336
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Helicobacter pylori cytotoxin‑associated gene A activates tumor necrosis factor‑α and interleukin‑6 in gastric epithelial cells through P300/CBP‑associated factor‑mediated nuclear factor‑κB p65 acetylation

Qiong Lin, Hui Xu, Xintao Chen, Guorong Tang, Lan Gu, Yehong Wang
Pages: 6337-6345
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Article

16S rDNA PCR-DGGE and sequencing in the diagnosis of neonatal late-onset septicemia

Dong Liu, Lizhong Du, Jialin Yu, Luquan Li, Qing Ai, Jinxing Feng, Chao Song
Pages: 6346-6352
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Article

Oxidative stress biomarkers and paraoxonase 1 polymorphism frequency in farmers occupationally exposed to pesticides

Chiara Costa, Silvia Gangemi, Federica Giambò, Venerando Rapisarda, Daniela Caccamo, Concettina Fenga
Pages: 6353-6357
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Oncolytic adenovirus‑mediated mda‑7/IL‑24 expression suppresses osteosarcoma growth and enhances sensitivity to doxorubicin Retraction in /10.3892/mmr.2021.12476

Zongming Liu, Libo Xu, Hongping Yuan, Yang Zhang, Xiaona Zhang, Dongxu Zhao
Pages: 6358-6364
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Article

Involvement of an intracellular vesicular transport process in naked-sgRNA-mediated TRUE gene silencing

Masato Tamura, Mitsuoki Kawano, Mari Sato, Masayuki Nashimoto
Pages: 6365-6369
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Effects of Dangkwisoo‑san, a traditional herbal medicine for treating pain and blood stagnation, on the pacemaker activities of cultured interstitial cells of Cajal

Soon‑Ki Sung, Sung Jin Kim, Tae Seok Ahn, Noo Ri Hong, Hyun Soo Park, Young Kyu Kwon, Byung Joo Kim
Pages: 6370-6376
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Article

Baicalin alleviates diabetes‑associated cognitive deficits via modulation of mitogen-activated protein kinase signaling, brain‑derived neurotrophic factor and apoptosis

Ping Ma, Xiao‑Yuan Mao, Xiao‑Lei Li, Ying Ma, Yuan‑Dong Qiao, Zhao‑Qian Liu, Hong‑Hao Zhou, Yong‑Gang Cao
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Metformin suppresses intrahepatic coagulation activation in mice with lipopolysaccharide/D‑galactosamine‑induced fulminant hepatitis

Xianqiong Gong, Rui Duan, Jin‑E Ao, Qing Ai, Pu Ge, Ling Lin, Li Zhang
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Published online on: 10 August 2015

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Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

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Article Number: 32
Published online on: 06 November 2025

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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Published online on: 03 November 2025

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Published online on: 03 November 2025

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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

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Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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Published online on: 31 October 2025

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Article Number: 21
Published online on: 29 October 2025

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Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
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Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

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Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

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Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

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Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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