|
1
|
Chen Y, Liu K, Xu L, Chen H, Liu D, Zhang
X, Shi H, Han W, Wang Y, Zhao T, et al: HLA-mismatched
hematopoietic SCT without in vitro T-cell depletion for
myelodysplastic syndrome. Bone Marrow Transplant. 45:1333–1339.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kindwall-Keller T and Isola LM: The
evolution of hematopoietic SCT in myelodysplastic syndrome. Bone
Marrow Transplant. 43:597–609. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Polier G, Ding J, Konkimalla BV, Eick D,
Ribeiro N, Köhler R, Giaisi M, Efferth T, Desaubry L, Krammer PH
and Li-Weber M: Wogonin and related natural flavones are inhibitors
of CDK9 that induce apoptosis in cancer cells by transcriptional
suppression of Mcl-1. Cell Death Dis. 2:e1822011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chung HY, Jung YM, Shin DH, Lee JY, Oh MY,
Kim HJ, Jang KS, Jeon SJ, Son KH and Kong G: Anticancer effects of
wogonin in both estrogen receptor-positive and -negative human
breast cancer cell lines in vitro and in nude mice xenografts. Int
J Cancer. 122:816–822. 2008. View Article : Google Scholar
|
|
5
|
Li-Weber M: New therapeutic aspects of
flavones: The anticancer properties of Scutellaria and its main
active constituents Wogonin, Baicalein and Baicalin. Cancer Treat
Rev. 35:57–68. 2009. View Article : Google Scholar
|
|
6
|
Baumann S, Fas SC, Giaisi M, Müller WW,
Merling A, Gülow K, Edler L, Krammer PH and Li-Weber M: Wogonin
preferentially kills malignant lymphocytes and suppresses T-cell
tumor growth by inducing PLCgamma1-and Ca2+-dependent
apoptosis. Blood. 111:2354–2363. 2008. View Article : Google Scholar
|
|
7
|
Chow SE, Chang YL, Chuang SF and Wang JS:
Wogonin induced apoptosis in human nasopharyngeal carcinoma cells
by targeting GSK-3β and ΔNp63. Cancer Chemother Pharmacol.
68:835–845. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Lin CC, Kuo CL, Lee MH, Lai KC, Lin JP,
Yang JS, Yu CS, Lu CC, Chiang JH, Chueh FS and Chung JG: Wogonin
triggers apoptosis in human osteosarcoma U-2 OS cells through the
endoplasmic reticulum stress, mitochondrial dysfunction and
caspase-3-dependent signaling pathways. Int J Oncol. 39:217–224.
2011.PubMed/NCBI
|
|
9
|
Yang L, Zhang HW, Hu R, Yang Y, Qi Q, Lu
N, Liu W, Chu YY, You QD and Guo QL: Wogonin induces G(1) phase
arrest through inhibiting Cdk4 and cyclin D1 concomitant with an
elevation in p21Cip1 in human cervical carcinoma HeLa cells.
Biochem Cell Biol. 87:933–942. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
10
|
Lu N, Gao Y, Ling Y, Chen Y, Yang Y, Gu
HY, Qi Q, Liu W, Wang XT, You QD and Guo QL: Wogonin suppresses
tumor growth in vivo and VEGF-induced angiogenesis through
inhibiting tyrosine phosphorylation of VEGFR2. Life Sci.
82:956–963. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kelloff GJ, Crowell JA, Steele VE, Lubet
RA, Malone WA, Boone CW, Kopelovich L, Hawk ET, Lieberman R,
Lawrence JA, et al: Progress in cancer chemoprevention: Development
of diet-derived chemopreventive agents. J Nutr. 130(2 Suppl):
S467–S471. 2000.
|
|
12
|
Cheng YL, Lee SC, Lin SZ, Chang WL, Chen
YL, Tsai NM, Liu YC, Tzao C, Yu DS and Harn HJ: Anti-proliferative
A549 human activity of Bupleurum scrozonerifolium in lung cancer
cells in vitro and in vivo. Cancer Lett. 222:183–193. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Trivedi PP, Roberts PC, Wolf NA and
Swanborg RH: NK cells inhibit T cell proliferation via p21-mediated
cell cycle arrest. J Immunol. 174:4590–4597. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Canavese M, Santo L and Raje N: Cyclin
dependent kinases in cancer: Potential for therapeutic
intervention. Cancer Biol Ther. 13:451–457. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Vermeulen K, Van Bockstaele DR and
Berneman ZN: The cell cycle: A review of regulation, deregulation
and therapeutic targets in cancer. Cell Prolif. 36:131–149. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Nakagawa T, Matozaki S, Murayama T,
Nishimura R, Tsutsumi M, Kawaguchi R, Yokoyama Y, Hikiji K, Isobe T
and Chihara K: Establishment of a leukaemic cell line from a
patient with acquisition of chromosomal abnormalities during
disease progression in myelodysplastic syndrome. Br J Haematol.
85:469–476. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Xia G, Chen B, Ding J, Gao C, Lu H, Shao
Z, Gao F and Wang X: Effect of magnetic Fe3O4
nanoparticles with 2-methoxyestradiol on the cell-cycle progression
and apoptosis of myelodysplastic syndrome cells. Int J
Nanomedicine. 6:1921–1927. 2011.
|
|
18
|
Jiang Z, Chen BA, Xia GH, Wu Q, Zhang Y,
Hong TY, Zhang W, Cheng J, Gao F, Liu LJ, et al: The reversal
effect of magnetic Fe3O4 nanoparticles loaded with cisplatin on
SKOV3/DDP ovarian carcinoma cells. Int J Nanomedicine. 4:107–114.
2009.PubMed/NCBI
|
|
19
|
Surh YJ: Cancer chemoprevention with
dietary phytochemicals. Nat Rev Cancer. 3:768–780. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Karunagaran D, Joseph J and Kumar TR: Cell
growth regulation. Adv Exp Med Biol. 595:245–268. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang M, Liu LP, Chen Y, Tian XY, Qin J,
Wang D, Li Z and Mo SL: Wogonin induces apoptosis in RPMI 8226, a
human myeloma cell line, by downregulating phospho-Akt and
overexpressing Bax. Life Sci. 92:55–62. 2013. View Article : Google Scholar
|
|
22
|
Wang L, Zhang H, Chen B, Xia G, Wang S,
Cheng J, Shao Z, Gao C, Bao W, Tian L, et al: Effect of magnetic
nanoparticles on apoptosis and cell cycle induced by wogonin in
Raji cells. Int J Nanomedicine. 7:789–798. 2012.PubMed/NCBI
|
|
23
|
Elmore S: Apoptosis: A review of
programmed cell death. Toxicol Pathol. 35:495–516. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Hengartner MO: The biochemistry of
apoptosis. Nature. 407:770–776. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
25
|
Chen B, Liang Y, Wu W, Cheng J, Xia G, Gao
F, Ding J, Gao C, Shao Z, Li G, et al: Synergistic effect of
magnetic nanoparticles of Fe3O4 with gambogic
acid on apoptosis of K562 leukemia cells. Int J Nanomedicine.
4:251–259. 2009. View Article : Google Scholar :
|
|
26
|
Cotter TG: Apoptosis and cancer: The
genesis of a research field. Nat Rev Cancer. 9:501–507. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Leber B, Lin J and Andrews DW: Still
embedded together binding to membranes regulates Bcl-2 protein
interactions. Oncogene. 29:5221–5230. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Youle RJ and Strasser A: The BCL-2 protein
family: Opposing activities that mediate cell death. Nat Rev Mol
Cell Biol. 9:47–59. 2008. View Article : Google Scholar
|
|
29
|
Kroemer G and Reed JC: Mitochondrial
control of cell death. Nat Med. 6:513–519. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Wei MC, Zong WX, Cheng EH, Lindsten T,
Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB,
Korsmeyer SJ, et al: Proapoptotic BAX and BAK: A requisite gateway
to mitochondrial dysfunction and death. Science. 292:727–730. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sanchez-Alczar JA, Khodjakov A and
Schneider E: Anticancer drugs induce increased mitochondrial
cytochrome c expression that precedes cell death. Cancer Res.
61:1038–1044. 2001.
|
|
32
|
Riedl SJ and Salvesen GS: The apoptosome:
Signaling platform of cell death. Nat Rev Mol Cell Biol. 8:405–413.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Caserta TM, Smith AN, Gultice AD, Reedy MA
and Brown TL: Q-VD-OPh, a broad spectrum caspase inhibitor with
potent antiapoptotic properties. Apoptosis. 8:345–352. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Fadeel B and Orrenius S: Apoptosis: A
basic biological phenomenon with wide-ranging implications in human
disease. J Intern Med. 258:479–517. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Agarwal A, Mahfouz RZ, Sharma RK, Sarkar
O, Mangrola D and Mathur PP: Potential biological role of poly
(ADP-ribose) polymerase (PARP) in male gametes. Reprod Biol
Endocrinol. 7:1432009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Danial NN: BCL-2 family proteins: Critical
checkpoints of apoptotic cell death. Clin Cancer Res. 13:7254–7263.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Mahfouz RZ, Said TM, Mangrola D, et al:
Potential roles of poly (ADP-ribose) polymerase in male
reproduction. Arch Med Sci. 5:S92–S98. 2009.
|
|
38
|
Zhang PX, Li HM, Chen D, Ni J, Kang Y and
Wang S: Oleanolic acid induces apoptosis in human leukemia cells
through caspase activation and poly (ADP-ribose) polymerase
cleavage. Acta Biochim Biophys Sin (Shanghai). 39:803–809. 2007.
View Article : Google Scholar
|
|
39
|
Kroemer G, Galluzzi L and Brenner C:
Mitochondrial membrane permeabilization in cell death. Physiol Rev.
87:99–163. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Liu YM, Wang X, Nawaz A, Kong ZH, Hong Y,
Wang CH and Zhang JJ: Wogonin ameliorates lipotoxicity-induced
apoptosis of cultured vascular smooth muscle cells via interfering
with DAG-PKC pathway. Acta Pharmacol Sin. 32:1475–1482. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Liu Q, Hilsenbeck S and Gazitt Y: Arsenic
trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or
G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and
synergy with APO2/TRAIL. Blood. 101:4078–4087. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Zhang HW, Yang Y, Zhang K, Qiang L, Yang
L, Yang L, Hu Y, Wang XT, You QD and Guo QL: Wogonin induced
differentiation and G1 phase arrest of human U-937 leukemia cells
via PKC delta phosphorylation. Eur J Pharmacol. 591:7–12. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
He L, Lu N, Dai Q, Zhao Y, Zhao L, Wang H,
Li Z, You Q and Guo Q: Wogonin induced G1 cell cycle arrest by
regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in
human colorectal cancer carcinoma cells. Toxicology. 312:36–47.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Malumbres M and Barbacid M: Mammalian
cyclin-dependent kinases. Trends Biochem Sci. 30:630–641. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Paulovich AG and Hartwell LH: A checkpoint
regulates the rate of progression through S phase in S. cerevisiae
in response to DNA damage. Cell. 82:841–847. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Walker JL and Assoian RK:
Integrin-dependent signal trans,duction regulating cyclin D1
expression and G1 phase cell cycle progression. Cancer Metastasis
Rev. 24:383–393. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Lew DJ and Kornbluth S: Regulatory roles
of cyclin dependent kinase phosphorylation in cell cycle control.
Curr Opin Cell Biol. 8:795–804. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Harbour JW and Dean DC: Rb function in
cell-cycle regulation and apoptosis. Nat Cell Biol. 2:E65–E67.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Schwartz GK and Shah MA: Targeting the
cell cycle: A new approach to cancer therapy. J Clin Oncol.
23:9408–9421. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Abukhdeir AM and Park BH: P21 and p27:
Roles in carcinogenesis and drug resistance. Expert Rev Mol Med.
10:e192008. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Gartel AL and Tyner AL: The role of the
cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer
Ther. 1:639–649. 2002.PubMed/NCBI
|
