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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2015 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Lipopolysaccharide-induced tumor necrosis factor-α factor enhances inflammation and is associated with cancer (Review)

Junrong Zou, Pei Guo, Nonghua Lv, Deqiang Huang
Pages: 6399-6404
Published online on: 25 August 2015

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Review Open Access

Associations between activation-induced cytidine deaminase/apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like cytidine deaminase expression, hepatitis B virus (HBV) replication and HBV-associated liver disease (Review)

Xiuting He, Jie Li, Jing Wu, Manli Zhang, Pujun Gao
Pages: 6405-6414
Published online on: 10 September 2015

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Review

Roles of neural precursor cell expressed, developmentally downregulated 9 in tumor-associated cellular processes (Review)

Sisen Zhang, Lihua Wu
Pages: 6415-6421
Published online on: 24 August 2015

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Article Open Access

Effect of cadmium on the expression levels of interleukin-1α and interleukin-10 cytokines in human lung cells

Caroline Odewumi, Lekan M. Latinwo, Andre Sinclair, Veera L.D. Badisa, Ahkinyala Abdullah, Ramesh B. Badisa
Pages: 6422-6426
Published online on: 10 September 2015

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Article Open Access

Combination of early and delayed ischemic postconditioning enhances brain-derived neurotrophic factor production by upregulating the ERK-CREB pathway in rats with focal ischemia

Hui Wu, Shao‑Feng Yang, Jiong Dai, Yong‑Ming Qiu, Yi‑Feng Miao, Xiao‑Hua Zhang
Pages: 6427-6434
Published online on: 15 September 2015

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Article Open Access

Characterization of highly proliferative secondary tumor clusters along host blood vessels in malignant glioma

Ting‑Chung Wang, Chun‑Yu Cheng, Wei‑Hsun Yang, Wen‑Cheng Chen, Pey‑Jium Chang
Pages: 6435-6444
Published online on: 18 August 2015

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Article Open Access

Epithelial membrane protein 3 functions as an oncogene and is regulated by microRNA-765 in primary breast carcinoma

Xiao Chun Hong, Yuan Jian Fen, Guo Chun Yan, Hong Hong, Cao Hong Yan, Li Wei Bing, Yu Hai Zhong
Pages: 6445-6450
Published online on: 14 September 2015

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Article Open Access

Astragalus polysaccharides affect insulin resistance by regulating the hepatic SIRT1-PGC-1α/PPARα-FGF21 signaling pathway in male Sprague Dawley rats undergoing catch-up growth

Chengying Gu, Yipeng Zeng, Zhaosheng Tang, Chaoxun Wang, Yanju He, Xinge Feng, Ligang Zhou
Pages: 6451-6460
Published online on: 25 August 2015

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Article Open Access

Apigenin inhibits the proliferation of adenoid cystic carcinoma via suppression of glucose transporter-1

Jin Fang, Yang‑Yang Bao, Shui‑Hong Zhou, Jun Fan
Pages: 6461-6466
Published online on: 20 August 2015

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Article Open Access

Hypoxia-induced autophagy contributes to the invasion of salivary adenoid cystic carcinoma through the HIF-1α/BNIP3 signaling pathway

Haiwei Wu, Shengyun Huang, Zhanwei Chen, Wenlei Liu, Xiaoqing Zhou, Dongsheng Zhang
Pages: 6467-6474
Published online on: 26 August 2015

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Article Open Access

Hypericin-mediated photodynamic therapy induces apoptosis in K562 human leukemia cells through JNK pathway modulation

Yixiao Xu, Dexuan Wang, Zhizhi Zhuang, Keke Jin, Lvzhen Zheng, Qing Yang, Kunyuan Guo
Pages: 6475-6482
Published online on: 27 August 2015

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Article Open Access

Melittin, a honeybee venom‑derived antimicrobial peptide, may target methicillin‑resistant Staphylococcus aureus

Ji Hae Choi, A Yeung Jang, Shunmei Lin, Sangyong Lim, Dongho Kim, Kyungho Park, Sang‑Mi Han, Joo‑Hong Yeo, Ho Seong Seo
Pages: 6483-6490
Published online on: 01 September 2015

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Article Open Access

Downregulation of microRNA‑33a promotes cyclin‑dependent kinase 6, cyclin D1 and PIM1 expression and gastric cancer cell proliferation

Yudong Wang, Xinliang Zhou, Baoen Shan, Jing Han, Feifei Wang, Xiaojie Fan, Yalei Lv, Liang Chang, Wei Liu
Pages: 6491-6500
Published online on: 07 September 2015

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Article Open Access

Adapalene inhibits the activity of cyclin-dependent kinase 2 in colorectal carcinoma

Xi‑Nan Shi, Hongjian Li, Hong Yao, Xu Liu, Ling Li, Kwong‑Sak Leung, Hsiang‑Fu Kung, Marie Chia‑Mi Lin
Pages: 6501-6508
Published online on: 10 September 2015

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Article Open Access

Adenosine deaminase and adenosine kinase expression in human glioma and their correlation with glioma‑associated epilepsy

Jun Huang, Yujiao He, Mingna Chen, Juan Du, Guoliang Li, Shuyu Li, Weiping Liu, Xiaoyan Long
Pages: 6509-6516
Published online on: 02 September 2015

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Article Open Access

Defective heat shock factor 1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigen‑transformed MEF cells

Qiying Jiang, Zhi Zhang, Shulian Li, Zhaoyang Wang, Yuanfang Ma, Yanzhong Hu
Pages: 6517-6526
Published online on: 09 September 2015

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Article Open Access

Expression and purification of functional HMGB1 A box by fusion with SUMO

Wen‑Song Ge, Jian‑Gao Fan, Ying‑Wei Chen, Lei‑Ming Xu
Pages: 6527-6532
Published online on: 09 September 2015

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Article Open Access

Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo

Le Tao, Yigang Zeng, Jun Wang, Zhihong Liu, Bing Shen, Jifu Ge, Yong Liu, Yifeng Guo, Jianxin Qiu
Pages: 6533-6546
Published online on: 15 September 2015

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Article Open Access

Bone morphogenetic protein 2 regulates the differentiation of nitrergic enteric neurons by modulating Smad1 signaling in slow transit constipation

Xuliang Liu, Shangming Liu, Yanan Xu, Xiuqin Liu, Daqing Sun
Pages: 6547-6554
Published online on: 07 September 2015

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Article Open Access

4‑Hydroxyisoleucine improves insulin resistance in HepG2 cells by decreasing TNF‑α and regulating the expression of insulin signal transduction proteins

Feng Gao, Liumeng Jian, Mohammad Ishraq Zafar, Wen Du, Qin Cai, Raja Adeel Shafqat, Furong Lu
Pages: 6555-6560
Published online on: 07 September 2015

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Article Open Access

MicroRNA signatures from multidrug‑resistant Mycobacterium tuberculosis

Na Ren, Guiju Gao, Yue Sun, Ling Zhang, Huizhu Wang, Wenhao Hua, Kanglin Wan, Xingwang Li
Pages: 6561-6567
Published online on: 28 August 2015

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Article Open Access

DNA methylation patterns of protein-coding genes and long non-coding RNAs in males with schizophrenia

Qi Liao, Yunliang Wang, Jia Cheng, Dongjun Dai, Xingyu Zhou, Yuzheng Zhang, Jinfeng Li, Honglei Yin, Shugui Gao, Shiwei Duan
Pages: 6568-6576
Published online on: 25 August 2015

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Article Open Access

Expression of leukemia inhibitory factor in the rat retina following acute ocular hypertension

Qianqian Hu, Changquan Huang, Yao Wang, Renyi Wu
Pages: 6577-6583
Published online on: 03 September 2015

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Article Open Access

In silico analysis of the molecular mechanism of postmenopausal osteoporosis

Yanqing Liu, Yueqiu Wang, Nailong Yang, Suning Wu, Yanhua Lv, Lili Xu
Pages: 6584-6590
Published online on: 02 September 2015

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Article Open Access

Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Pages: 6591-6597
Published online on: 07 September 2015

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Article Open Access

Decreased 13N‑labeled ammonia uptake in the ipsilateral and contralateral hemispheres following carotid endarterectomy

Tao Wang, Xuemei Wang, Yulin He, Tao Zhang, Jianqiang Song, Xia Bai, Chunlei Han
Pages: 6598-6604
Published online on: 09 September 2015

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Article Open Access

Effects of ELL-associated factor 2 on ultraviolet radiation-induced cataract formation in mice

Yanhua Jiang, Rongrong Fu, Jiangyue Zhao, Di Wu, Guang Qiao, Ruoxi Li, Jinsong Zhang
Pages: 6605-6611
Published online on: 02 September 2015

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Article Open Access

Low temperature induces cryoinjury in mouse corneal endothelial cells by stimulating the Stk11-p53 signal pathway

Sijie Zhao, Xinfeng Fei, Te Liu, Yan Liu
Pages: 6612-6616
Published online on: 09 September 2015

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Article Open Access

RNA interference‑mediated knockdown of translationally controlled tumor protein induces apoptosis, and inhibits growth and invasion in glioma cells

Hua Jin, Xuexin Zhang, Jun Su, Yueqiu Teng, Huan Ren, Lizhuang Yang
Pages: 6617-6625
Published online on: 02 September 2015

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Article Open Access

An investigation into the expression and mechanism of action of urotensin II in chronic pressure-overloaded rat hearts

Wenyuan Liu, Qinghua Han, Qinghua Liu, Gang Liang, Jin Wang, Chengfang Liu
Pages: 6626-6634
Published online on: 25 August 2015

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Article Open Access

RNAi-mediated knockdown of the CLN3 gene inhibits proliferation and promotes apoptosis in drug-resistant ovarian cancer cells

Dongwei Mao, Jianhua Che, Shiyu Han, Honghui Zhao, Yumei Zhu, Hong Zhu
Pages: 6635-6641
Published online on: 21 August 2015

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Article Open Access

Retinoic acid‑incorporated glycol chitosan nanoparticles inhibit the expression of Ezh2 in U118 and U138 human glioma cells Retraction in /10.3892/mmr.2016.5130

Hu‑Chen Lu, Jun Ma, Zong Zhuang, Yao Zhang, Hui‑Lin Cheng, Ji‑Xin Shi
Pages: 6642-6648
Published online on: 07 September 2015

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Article Open Access

Fucoidan inhibits proliferation of the SKM-1 acute myeloid leukaemia cell line via the activation of apoptotic pathways and production of reactive oxygen species

Chunmei Wei, Qing Xiao, Xingyi Kuang, Tao Zhang, Zesong Yang, Li Wang
Pages: 6649-6655
Published online on: 25 August 2015

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Article Open Access

Cyclic RNA hsa‑circ‑000595 regulates apoptosis of aortic smooth muscle cells

Chengfei Zheng, Hui Niu, Ming Li, Hongkun Zhang, Zhenggang Yang, Lu Tian, Ziheng Wu, Donglin Li, Xudong Chen
Pages: 6656-6662
Published online on: 28 August 2015

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Article Open Access

Abnormal alterations in the Ca2+/CaV1.2/calmodulin/caMKII signaling pathway in a tremor rat model and in cultured hippocampal neurons exposed to Mg2+-free solution

Xintong Lv, Feng Guo, Xiaoxue Xu, Zaixing Chen, Xuefei Sun, Dongyu Min, Yonggang Cao, Xianbao Shi, Lei Wang, Tianbao Chen, Chris Shaw, Huiling Gao, Liying Hao, Jiqun Cai
Pages: 6663-6671
Published online on: 18 August 2015

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Article Open Access

Evaluation of a combinatorial RNAi lentivirus vector targeting foot-and-mouth disease virus in vitro and in vivo

Xiaoxi Zhang, Haixue Zheng, Minjun Xu, Yu Zhou, Xiangping Li, Fan Yang, Qingyou Liu, Deshun Shi
Pages: 6672-6678
Published online on: 25 August 2015

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Article Open Access

Integrated analysis of differential gene expression profiles in hippocampi to identify candidate genes involved in Alzheimer's disease

Wanhua Hu, Xiaodong Lin, Kelong Chen
Pages: 6679-6687
Published online on: 28 August 2015

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Article Open Access

Potential application of injectable chitosan hydrogel treated with siRNA in chronic rhinosinusitis therapy

Cheng Cao, Chunhong Yan, Zhiqiang Hu, Shao Zhou
Pages: 6688-6694
Published online on: 21 August 2015

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Article Open Access

IDH1R132H decreases the proliferation of U87 glioma cells through upregulation of microRNA-128a

Quan‑Min Nie, Ying‑Ying Lin, Xi Yang, Lin Shen, Lie‑Mei Guo, Shuang‑Lin Que, Xiao‑Xiong Li, Jian‑Wei Ge, Gui‑Song Wang, Wen‑Hao Xiong, Pin Guo, Yong‑Ming Qiu
Pages: 6695-6701
Published online on: 24 August 2015

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Article Open Access

Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma Corrigendum in /mmr/12/5/7815

Liang Chang, Dan Zhao, Hui‑Bin Liu, Qiu‑Shi Wang, Ping Zhang, Chen‑Long Li, Wen‑Zhong Du, Hong‑Jun Wang, Xing Liu, Zhi‑Ren Zhang, Chuan‑Lu Jiang
Pages: 6702-6710
Published online on: 18 August 2015

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Article Open Access

Effects of intermedin on proliferation, apoptosis and the expression of OPG/RANKL/M-CSF in the MC3T3-E1 osteoblast cell line

Hongfei Ren, Hongyu Ren, Xue Li, Dongdong Yu, Shuai Mu, Zhiguang Chen, Qin Fu
Pages: 6711-6717
Published online on: 15 September 2015

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Article Open Access

Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction

Jun-Min Yu, Xiao-Bo Zhang, Wen Jiang, Hui-Dong Wang, Yi-Na Zhang
Pages: 6718-6726
Published online on: 09 September 2015

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Article Open Access

Synergistic immunotherapeutic effects of Lycium barbarum polysaccharide and interferon-α2b on the murine Renca renal cell carcinoma cell line in vitro and in vivo

Shiyou Chen, Lunan Liang, Ying Wang, Jianhun Diao, Chunxiong Zhao, Gang Chen, Yunfeng He, Chunli Luo, Xiaohou Wu, Yao Zhang
Pages: 6727-6737
Published online on: 20 August 2015

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Article Open Access

STAT3‑regulated long non‑coding RNAs lnc‑7SK and lnc‑IGF2‑AS promote hepatitis C virus replication

Yulin Xiong, Ming Jia, Jing Yuan, Changjiang Zhang, Yan Zhu, Xuemei Kuang, Lin Lan, Xiaohong Wang
Pages: 6738-6744
Published online on: 01 September 2015

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Article Open Access

Isorhamnetin inhibits cell proliferation and induces apoptosis in breast cancer via Akt and mitogen‑activated protein kinase kinase signaling pathways

Shan Hu, Liming Huang, Liwei Meng, He Sun, Wei Zhang, Yingchun Xu
Pages: 6745-6751
Published online on: 28 August 2015

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Article Open Access

Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection

Jun Tao, Xiao Yang, Pengchao Li, Jifu Wei, Xiaheng Deng, Yidong Cheng, Chao Qin, Xiaobing Ju, Xiaoxin Meng, Jie Li, Min Gu, Qiang Lu, Changjun Yin
Pages: 6752-6760
Published online on: 27 August 2015

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Article Open Access

Increased B-type-natriuretic peptide promotes myocardial cell apoptosis via the B-type-natriuretic peptide/long non-coding RNA LSINCT5/caspase-1/interleukin 1β signaling pathway

Xian Zhang, Minglei Sha, Yuting Yao, Jia Da, Dadao Jing
Pages: 6761-6767
Published online on: 25 August 2015

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Article Open Access

Generation and characterization of mice with a conditional null allele of the HtrA4 gene

Ju Liu, Yan Li, Josephine Hoh
Pages: 6768-6774
Published online on: 03 September 2015

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Article Open Access

Efficacy of thymosin α1 and interferon α for the treatment of severe acute pancreatitis in a rat model

Xiaoqin Wang, Xiaoyan Zeng, Bo Yang, Shan Zhao, Wei Chen, Xuan Guo
Pages: 6775-6781
Published online on: 01 September 2015

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Article Open Access

Mucin 1 gene silencing inhibits the growth of SMMC-7721 human hepatoma cells through Bax-mediated mitochondrial and caspase-8-mediated death receptor apoptotic pathways

Hongyan Yuan, Juan Wang, Fengli Wang, Nannan Zhang, Qiongshu Li, Fei Xie, Tanxiu Chen, Ruiping Zhai, Fang Wang, Yingying Guo, Weihua Ni, Guixiang Tai
Pages: 6782-6788
Published online on: 14 September 2015

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Article

Polo‑like kinase 3 inhibits osteosarcoma cell proliferation and tumorigenesis via cooperative interaction with p21

Honglin Lv, Guangting Gao, Linlin Zhang, Yujie Sun
Pages: 6789-6796
Published online on: 09 September 2015

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Article

Involvement of the Wnt signaling pathway in feeder‑free culture of human induced pluripotent stem cells

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 6797-6800
Published online on: 10 September 2015

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Article

Knockdown of myosin VI by lentivirus-mediated short hairpin RNA suppresses proliferation of melanoma

Hui Li, Fusheng Zhou, Hongyan Wang, Da Lin, Gang Chen, Xianbo Zuo, Liangdan Sun, Xuejun Zhang, Sen Yang
Pages: 6801-6806
Published online on: 28 August 2015

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Article

Electroacupuncture ameliorates learning and memory in rats with cerebral ischemia-reperfusion injury by inhibiting oxidative stress and promoting p-CREB expression in the hippocampus

Ruhui Lin, Yukun Lin, Jing Tao, Bin Chen, Kunqiang Yu, Jixiang Chen, Xiaojie Li, Li‑Dian Chen
Pages: 6807-6814
Published online on: 14 September 2015

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Article

Anti-proliferative and cytoskeleton-disruptive effects of icariin on HepG2 cells

Zhi‑Min Wang, Nan Song, Yan‑Ling Ren
Pages: 6815-6820
Published online on: 02 September 2015

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Article

Azorella compacta methanolic extract induces apoptosis via activation of mitogen-activated protein kinase

Min Hee Sung, Ok-Kyoung Kwon, Sei-Ryang Oh, Joongku Lee, Sang-Hong Park, Sang Bae Han, Kyung-Seop Ahn
Pages: 6821-6828
Published online on: 10 September 2015

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Article

Amplification refractory mutation system polymerase chain reaction versus optimized polymerase chain reaction restriction-fragment length polymorphism for apolipoprotein E genotyping of majorly depressed patients

Hongmin You, Jin Chen, Jingjing Zhou, Hua Huang, Junxi Pan, Ziye Wang, Lin Lv, Lujun Zhang, Juan Li, Bin Qin, Yongtao Yang, Peng Xie
Pages: 6829-6834
Published online on: 25 August 2015

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Article

Induction differentiation of rabbit adipose‑derived stromal cells into insulin‑producing cells in vitro

Yu Sun, Mengchao Zhang, Shangwei Ji, Lin Liu
Pages: 6835-6840
Published online on: 09 September 2015

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Article

Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting reactive oxygen species-activated extracellular signal-regulated kinase 1/2 in H9c2 cardiac myocytes

Mi‑Hua Liu, Xiao‑Long Lin, Yuan Zhang, Jun He, Tian‑Ping Tan, Shao‑Jian Wu, Jun Liu, Wei Tian, Li Chen, Shan Yu, Jian Li, Cong Yuan
Pages: 6841-6848
Published online on: 21 August 2015

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Article

Spironolactone inhibits podocyte motility via decreasing integrin β1 and increasing integrin β3 in podocytes under high-glucose conditions

Zhuo Li, Li Zhang, Wei Shi, Yuanhan Chen, Hong Zhang, Shuangxin Liu, Xinling Liang, Ting Ling, Chunping Yu, Zhongshun Huang, Xiaofan Tan, Xinchen Zhao, Zhiming Ye, Bin Zhang, Wenjian Wang, Ruizhao Li, Jianchao Ma
Pages: 6849-6854
Published online on: 07 September 2015

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Significance of the quantitative measurement of the chr16: 51320015 integration site in hepatocytes of patients with chronic hepatitis B

Peng Ruan, Xiufang Dai, Zequn Sun, Chunfang Zhou, Fan Yang
Pages: 6855-6860
Published online on: 11 September 2015

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Knockdown of homeobox A5 by small hairpin RNA inhibits proliferation and enhances cytarabine chemosensitivity of acute myeloid leukemia cells

Na Li, Xiuhong Jia, Jianyong Wang, Youjie Li, Shuyang Xie
Pages: 6861-6866
Published online on: 15 September 2015

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Article

Microarray data analysis of neuroblastoma: Expression of SOX2 downregulates the expression of MYCN

Juntao Bao, Luying Qin, Lingling Cui, Xiaohui Wang, Qinglei Meng, Linchao Zhu, Shufeng Zhang
Pages: 6867-6872
Published online on: 10 September 2015

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Apigenin attenuates myocardial ischemia/reperfusion injury via the inactivation of p38 mitogen‑activated protein kinase

Xia Yang, Junlan Yang, Jing Hu, Xiaoqing Li, Xianjiao Zhang, Zilin Li
Pages: 6873-6878
Published online on: 07 September 2015

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Article

Ultra‑performance liquid chromatography coupled with quadrupole time‑of‑flight mass spectrometry‑based metabolic profiling of human serum prior to and following radical resection of colorectal carcinoma

Lufang Chen, Chunxia Zhang, Qifeng Gui, Yue Chen, Yunmei Yang
Pages: 6879-6886
Published online on: 03 September 2015

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Article

Gelsolin inhibits the proliferation and invasion of the 786-0 clear cell renal cell carcinoma cell line in vitro

Xiaoling Zhu, Limin Cai, Qinggang Meng, Xiaoming Jin
Pages: 6887-6894
Published online on: 10 September 2015

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Article

Therapeutic effects of the dipeptidyl peptidase-IV inhibitor, sitagliptin, on non-alcoholic steatohepatitis in FLS-ob/ob male mice

Takumi Onoyama, Masahiko Koda, Toshiaki Okamoto, Manabu Kishina, Tomomitsu Matono, Takaaki Sugihara, Yoshikazu Murawaki
Pages: 6895-6902
Published online on: 15 September 2015

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Article

MicroRNA-146b inhibition augments hypoxia-induced cardiomyocyte apoptosis

Jing‑Wei Li, Si‑Yi He, Ze‑Zhou Feng, Liang Zhao, Wei‑Kun Jia, Peng Liu, Yun Zhu, Zhao Jian, Ying‑Bin Xiao
Pages: 6903-6910
Published online on: 15 September 2015

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Electroacupuncture promotes neural stem cell proliferation and neurogenesis in the dentate gyrus of rats following stroke via upregulation of Notch1 expression

Junhong Zhao, Minghong Sui, Xiao Lü, Dongmei Jin, Zhiqiang Zhuang, Tiebin Yan
Pages: 6911-6917
Published online on: 02 September 2015

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Article

MicroRNA-122 mimic transfection contributes to apoptosis in HepG2 cells

Hongyan Huang, Yueyong Zhu, Shaoyang Li
Pages: 6918-6924
Published online on: 26 August 2015

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Treatment of experimental non‑alcoholic steatohepatitis by targeting α7 nicotinic acetylcholine receptor‑mediated inflammatory responses in mice

Zhou Zhou, Ying‑Chao Liu, Xiao‑Mei Chen, Fu‑Qiang Li, Xiao‑Juan Tong, Yue‑Ping Ding, Cui‑Lan Tang
Pages: 6925-6931
Published online on: 10 September 2015

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Article

Pitavastatin attenuates monocyte activation in response to orthopedic implant‑derived wear particles by suppressing the NF‑κB signaling pathway

Zehua Zhang, Fei Dai, Peng Cheng, Fei Luo, Tianyong Hou, Qiang Zhou, Zhao Xie, Moyuan Deng, Jian‑Zhong Xu
Pages: 6932-6938
Published online on: 09 September 2015

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Involvement of the mitogen‑activated protein kinase signaling pathway in osteoprotegerin‑induced inhibition of osteoclast differentiation and maturation

Yingxiao Fu, Jianhong Gu, Yi Wang, Yan Yuan, Xuezhong Liu, Jianchun Bian, Zongping Liu
Pages: 6939-6945
Published online on: 02 September 2015

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Ginsenoside Rh2 attenuates allergic airway inflammation by modulating nuclear factor‑κB activation in a murine model of asthma

Liang Chang Li, Hong Mei Piao, Ming Yu Zheng, Zhen Hua Lin, Yun Ho Choi, Guang Hai Yan
Pages: 6946-6954
Published online on: 28 August 2015

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Flagellin influences the expression of a variety of important cytokines and chemokines without affecting the immune status of umbilical cord mesenchymal stem cells

Quansheng Li, Yu Ma, Li Li, Ji Bao, Li Zhang
Pages: 6955-6961
Published online on: 01 September 2015

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Article

Sirtuin 1 regulates lipid metabolism associated with optic nerve regeneration

Yan Zhang, Hongyang Li, Yongmei Cao, Maonian Zhang, Shihui Wei
Pages: 6962-6968
Published online on: 02 September 2015

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Article

Fms‑like tyrosine kinase 3 ligand is required for thymic dendritic cell generation from bone marrow‑derived CD117+ hematopoietic progenitor cells

Yunyun Xu, Dong Jiang, Yizhou Hu, Yiping Li, Xueguang Zhang, Jian Wang, Yong Wang
Pages: 6969-6975
Published online on: 11 September 2015

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Article

ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells

Tianxiao Li, Gang Yuan, Lin Zhang, Lijun Ye, Shuxia Li, Yuhua Fan, Jian Sun
Pages: 6976-6984
Published online on: 08 September 2015

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Article

Screening of biomarkers in cervical squamous cell carcinomas via gene expression profiling

Bing Chen, Chundong Li, Lei Zhang, Jiahui Lv, Ying Tong
Pages: 6985-6989
Published online on: 14 September 2015

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Article

Cigarette smoke modulates PC3 prostate cancer cell migration by altering adhesion molecules and the extracellular matrix

Suping Yang, Minica Long, Souvenir D. Tachado, Seyha Seng
Pages: 6990-6996
Published online on: 09 September 2015

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Article

Effect of a functional polymorphism in the pre-miR-146a gene on the risk and prognosis of renal cell carcinoma

Zhilong Huang, Zhanpeng Lu, Jingchang Tian, Guangjian Wang, Zhenli Gao
Pages: 6997-7004
Published online on: 28 August 2015

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Article

Upregulation of microRNA-132 in gastric cancer promotes cell proliferation via retinoblastoma 1 targeting

Feng‑Yu Gao, Qun‑Ying Liu, Li Yuan, Shi‑Ying Xuan
Pages: 7005-7010
Published online on: 26 August 2015

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Article

MicroRNA‑21 regulates cell proliferation and apoptosis in H2O2‑stimulated rat spinal cord neurons

Genlong Jiao, Bin Pan, Zhigang Zhou, Lin Zhou, Zhizhong Li, Ziyong Zhang
Pages: 7011-7016
Published online on: 28 August 2015

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Article

Sardine protein diet increases plasma glucagon-like peptide-1 levels and prevents tissue oxidative stress in rats fed a high-fructose diet

Zohra Madani, Abdullah Sener, Willy J. Malaisse, Ait Yahia Dalila
Pages: 7017-7026
Published online on: 14 September 2015

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Article

Cytokine-induced killer cells induce apoptosis and inhibit the Akt/nuclear factor-κB signaling pathway in cisplatin-resistant human glioma U87MG cells

Yunpeng Cui, Feng Yang, Lu He
Pages: 7027-7032
Published online on: 21 August 2015

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Article

De-methylation of displacement loop of mitochondrial DNA is associated with increased mitochondrial copy number and nicotinamide adenine dinucleotide subunit 2 expression in colorectal cancer

Jinhang Gao, Shilei Wen, Hongying Zhou, Shi Feng
Pages: 7033-7038
Published online on: 26 August 2015

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Article

Intraoperative intravenous lidocaine exerts a protective effect on cell-mediated immunity in patients undergoing radical hysterectomy

Huan‑Liang Wang, Hong‑Dan Yan, Ya‑Yang Liu, Bao‑Zhu Sun, Rui Huang, Xiao‑Shuang Wang, Wei‑Fu Lei
Pages: 7039-7044
Published online on: 21 August 2015

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Article

Picropodophyllin inhibits the growth of Ewing's sarcoma cells through the insulin‑like growth factor‑1 receptor/Akt signaling pathway

Yong‑Tao Wu, Bao‑Jun Wang, Sheng‑Wu Miao, Jian‑Jun Gao
Pages: 7045-7050
Published online on: 28 August 2015

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Article

Screening a novel FGF3 antagonist peptide with anti-tumor effects on breast cancer from a phage display library

Wei Wang, Tao Chen, Haicheng Li, Yuhui Chen, Zhilong Wu, Tongming Feng, Xilin Zhang, Qiu Zhong, Qianhong Zhong, Guozhou Li, Lina Guo, Lin Zhou, Jie Zhou
Pages: 7051-7058
Published online on: 25 August 2015

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Article

Upregulation of microRNA-204 inhibits cell proliferation, migration and invasion in human renal cell carcinoma cells by downregulating SOX4

Deyao Wu, Huixing Pan, Yunfeng Zhou, Zichun Zhang, Ping Qu, Jian Zhou, Wanxiang Wang
Pages: 7059-7064
Published online on: 27 August 2015

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Article

Bone marrow mesenchymal stem cell implantation for the treatment of radioactivity‑induced acute skin damage in rats

Kai Zheng, Weizhen Wu, Shunliang Yang, Lianghu Huang, Jin Chen, Chungui Gong, Zhichao Fu, Linlin Zhang, Jianming Tan
Pages: 7065-7071
Published online on: 28 August 2015

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Article

miR‑34a inhibits colon cancer proliferation and metastasis by inhibiting platelet‑derived growth factor receptor α

Chunyan Li, Yulin Wang, Shuming Lu, Zhuqing Zhang, Hua Meng, Lina Liang, Yan Zhang, Bo Song
Pages: 7072-7078
Published online on: 28 August 2015

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Article

MicroRNA-101 inhibits the migration and invasion of intrahepatic cholangiocarcinoma cells via direct suppression of vascular endothelial growth factor-C

Gang Deng, Yinglu Teng, Feizhou Huang, Wanpin Nie, Lei Zhu, Wei Huang, Hongbo Xu
Pages: 7079-7085
Published online on: 21 August 2015

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Article

Ascorbic acid provides protection for human chondrocytes against oxidative stress

Zhiqiang Chang, Lifeng Huo, Pengfei Li, Yimin Wu, Pei Zhang
Pages: 7086-7092
Published online on: 20 August 2015

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Article

Naringin ameliorates cognitive deficits via oxidative stress, proinflammatory factors and the PPARγ signaling pathway in a type 2 diabetic rat model

Zhonghua Qi, Yinghui Xu, Zhanhua Liang, Sheng Li, Jie Wang, Yi Wei, Bin Dong
Pages: 7093-7101
Published online on: 20 August 2015

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Article

miR-155 is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO3

Jian Huang, Junhua Jiao, Weihua Xu, Huayang Zhao, Chunxiao Zhang, Yan Shi, Zhijian Xiao
Pages: 7102-7108
Published online on: 25 August 2015

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Article

Polymorphic variants in vitamin D signaling pathway genes and the risk of endometriosis-associated infertility

Malgorzata Szczepańska, Adrianna Mostowska, Przemyslaw Wirstlein, Jana Skrzypczak, Matthew Misztal, Paweł P. Jagodziński
Pages: 7109-7115
Published online on: 10 September 2015

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Article

Hexamethonium attenuates sympathetic activity and blood pressure in spontaneously hypertensive rats

Peng Li, Jue‑Xiao Gong, Wei Sun, Bin Zhou, Xiang‑Qing Kong
Pages: 7116-7122
Published online on: 10 September 2015

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Article

Upregulation of HIF‑1α protects neuroblastoma cells from hypoxia‑induced apoptosis in a RhoA‑dependent manner

Cui‑Ping Yin, Shang‑Hui Guan, Bo Zhang, Xue‑Xin Wang, Shou‑Wei Yue
Pages: 7123-7131
Published online on: 28 August 2015

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Article

Mangiferin attenuates contusive spinal cord injury in rats through the regulation of oxidative stress, inflammation and the Bcl‑2 and Bax pathway

Yang Luo, Changfeng Fu, Zhenyu Wang, Zhuo Zhang, Hongxia Wang, Yi Liu
Pages: 7132-7138
Published online on: 28 August 2015

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Article

A systems biology approach to detect key pathways and interaction networks in gastric cancer on the basis of microarray analysis

Leilei Guo, Chunhua Song, Peng Wang, Liping Dai, Jianying Zhang, Kaijuan Wang
Pages: 7139-7145
Published online on: 24 August 2015

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Article

Connexin 43 expressed in endothelial cells modulates monocyte‑endothelial adhesion by regulating cell adhesion proteins

Dongdong Yuan, Guoliang Sun, Rui Zhang, Chenfang Luo, Mian Ge, Gangjian Luo, Ziqing Hei
Pages: 7146-7152
Published online on: 28 August 2015

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Article

Expression and contribution of the HIF‑1α/VEGF signaling pathway to luteal development and function in pregnant rats

Lixiang Wu, Zhenghong Zhang, Xiaoyan Pan, Zhengchao Wang
Pages: 7153-7159
Published online on: 28 August 2015

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Article

Poor permeability and absorption affect the activity of four alkaloids from Coptis

Han‑Ming Cui, Qiu‑Yan Zhang, Jia‑Long Wang, Jian‑Long Chen, Yu‑Ling Zhang, Xiao‑Lin Tong
Pages: 7160-7168
Published online on: 03 September 2015

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Article

Upregulation of C-C chemokine receptor type 7 expression by membrane-associated prostaglandin E synthase-1/prostaglandin E2 requires glycogen synthase kinase 3β-mediated signal transduction in colon cancer cells

Shuyi Yu, Qian Hou, Huiping Sun, Jianping Liu, Jianzhe Li
Pages: 7169-7175
Published online on: 03 September 2015

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Article

Interferon-stimulated gene factor 3 complex is required for the induction of sterile α motif and HD domain-containing protein 1 expression by interferon-α in SMMC-7721 cells

Mengying Zhu, Jinsen Lu, Xiaowan Dong, Nan Zheng, Tingting Li, Zhangming Chen, Xiang Pan, Yongji Zhu, Hai Yan, Yuxian Shen, Songcheng Ying, Chunsong Hu
Pages: 7176-7180
Published online on: 15 September 2015

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Article

Intestinal mucosal injury induced by tryptase-activated protease-activated receptor 2 requires β-arrestin-2 in vitro

Shun Li, Jianqiang Guan, Mian Ge, Pinjie Huang, Yiquan Lin, Xiaoliang Gan
Pages: 7181-7187
Published online on: 14 September 2015

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Article Open Access

Pseudolaric acid B inhibits proliferation in SW579 human thyroid squamous cell carcinoma

Jinghua Yu, Peiyou Ren, Ting Zhong, Yalin Wang, Minghui Yan, Bianbian Xue, Rui Li, Chunyan Dai, Chunyu Liu, Guang Chen, Xiao‑Fang Yu
Pages: 7195-7202
Published online on: 05 October 2015

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Article Open Access

Rapamycin protects neurons from brain contusion‑induced inflammatory reaction via modulation of microglial activation

Qi Song, Dujiang Xie, Shiyong Pan, Weijun Xu
Pages: 7203-7210
Published online on: 01 October 2015

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Article Open Access

Investigation into hippocampal nerve cell damage through the mineralocorticoid receptor in mice

Kenroh Sasaki, Fumihiko Yoshizaki
Pages: 7211-7220
Published online on: 01 October 2015

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Article Open Access

Resveratrol inhibits canonical Wnt signaling in human MG-63 osteosarcoma cells

Yonggen Zou, Jiexiang Yang, Dianming Jiang
Pages: 7221-7226
Published online on: 21 September 2015

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Article Open Access

Bone marrow-derived mesenchymal stem cells inhibit the proliferation of hepatic stellate cells by inhibiting the transforming growth factor β pathway

Li‑Ting Zhang, Xue‑Qin Fang, Qing‑Feng Chen, Hong Chen, Ping Xiao, Xue‑Bin Peng, Sheng‑Xiang Zhang, Jun‑Feng Li, Xiao‑Rong Mao
Pages: 7227-7232
Published online on: 25 September 2015

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Article Open Access

Upregulation of long non-coding RNA HIF 1α-anti-sense 1 induced by transforming growth factor-β-mediated targeting of sirtuin 1 promotes osteoblastic differentiation of human bone marrow stromal cells

Yao Xu, Shilong Wang, Chaoliang Tang, Wenjun Chen
Pages: 7233-7238
Published online on: 01 October 2015

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Article Open Access

Aberrantly regulated dysadherin and B-cell lymphoma 2/B-cell lymphoma 2-associated X enhances tumorigenesis and DNA targeting drug resistance of liver cancer stem cells

Nan Jiang, Wei Chen, Jian‑Wen Zhang, Yang Li, Xian‑Cheng Zeng, Tong Zhang, Bin‑Sheng Fu, Hui‑Min Yi, Qi Zhang
Pages: 7239-7246
Published online on: 25 September 2015

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Article Open Access

Subcellular proteomic approach for identifying the signaling effectors of protein kinase C‑β2 under high glucose conditions in human umbilical vein endothelial cells

Min Zhang, Fang Sun, Fangfang Chen, Bo Zhou, Yaqian Duan, Hong Su, Xuebo Lin
Pages: 7247-7262
Published online on: 30 September 2015

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Article Open Access

Preparation and evaluation of an Arg-Gly-Asp-modified chitosan/hydroxyapatite scaffold for application in bone tissue engineering

Lin Chen, Baolin Li, Xiao Xiao, Qinggang Meng, Wei Li, Qian Yu, Jiaqi Bi, Yong Cheng, Zhiwei Qu
Pages: 7263-7270
Published online on: 25 September 2015

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Article Open Access

Repeated intra-nigrostriatal injection of phorbol myristate acetate induces microglial senescence in adult rats

Lin Liu, Xiao‑Guang Luo, Hong‑Mei Yu, Yu Feng, Yan Ren, Ya‑Fu Yin, Hong Shang, Zhi‑Yi He
Pages: 7271-7278
Published online on: 01 October 2015

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Article Open Access

OSSC1E-K19, a novel phytochemical component of Osteomeles schwerinae, prevents glycated albumin-induced retinal vascular injury in rats

Chan‑Sik Kim, Junghyun Kim, Kyuhyung Jo, Yun Mi Lee, Eunjin Sohn, Nam Hee Yoo, Jin Sook Kim
Pages: 7279-7284
Published online on: 01 October 2015

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Article Open Access

Wogonin inhibits the proliferation of myelodysplastic syndrome cells through the induction of cell cycle arrest and apoptosis

Huixia Lu, Feng Gao, Guofang Shu, Guohua Xia, Zeye Shao, Hangqin Lu, Keping Cheng
Pages: 7285-7292
Published online on: 23 September 2015

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Article Open Access

Comparison of antioxidant activity between green and roasted coffee beans using molecular methods

Alexandros Priftis, Dimitrios Stagos, Konstantinos Konstantinopoulos, Christina Tsitsimpikou, Demetrios A. Spandidos, Aristides M. Tsatsakis, Manolis N. Tzatzarakis, Demetrios Kouretas
Pages: 7293-7302
Published online on: 28 September 2015

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Article Open Access

Ki-67 labeling index affects tumor infiltration patterns of lung squamous cell carcinoma

Daisuke Masuda, Ryota Masuda, Tomohiko Matsuzaki, Naoko Imamura, Naohiro Aruga, Makiko Tanaka, Sadaki Inokuchi, Hiroshi Kijima, Masayuki Iwazaki
Pages: 7303-7309
Published online on: 24 September 2015

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Article Open Access

Regulatory mechanism of human vascular smooth muscle cell phenotypic transformation induced by NELIN

Changan Pei, Shiyong Qin, Minghai Wang, Shuguang Zhang
Pages: 7310-7316
Published online on: 25 September 2015

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Article Open Access

Fasudil, a Rho‑kinase inhibitor, prevents intima‑media thickening in a partially ligated carotid artery mouse model: Effects of fasudil in flow‑induced vascular remodeling

Xiangyu Zhang, Tao Zhang, Fu Gao, Qingle Li, Chenyang Shen, Yankui Li, Wei Li, Xiaoming Zhang
Pages: 7317-7325
Published online on: 01 October 2015

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Article Open Access

Molecular characteristics of recurrent triple-negative breast cancer

Chung‑Hsin Tsai, Jen‑Hwey Chiu, Chu‑Wen Yang, Jir‑You Wang, Yi‑Fang Tsai, Ling‑Ming Tseng, Wei‑Shone Chen, Yi‑Ming Shyr
Pages: 7326-7334
Published online on: 24 September 2015

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Article Open Access

Downregulation of P-gp, Ras and p-ERK1/2 contributes to the arsenic trioxide-induced reduction in drug resistance towards doxorubicin in gastric cancer cell lines

Yuan‑Yuan Zhao, Li Yu, Bao‑Ling Liu, Xin‑Jia He, Bi‑Yuan Zhang
Pages: 7335-7343
Published online on: 25 September 2015

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Article Open Access

Therapeutic efficacy of fibroblast growth factor 10 in a rabbit model of dry eye

Wenjing Zheng, Mingming Ma, Ergang Du, Zhengwei Zhang, Kelimu Jiang, Qing Gu, Bilian Ke
Pages: 7344-7350
Published online on: 25 September 2015

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Expression of aquaporin-4 and pathological characteristics of brain injury in a rat model of traumatic brain injury

Chengcheng Zhang, Jianqiang Chen, Hong Lu
Pages: 7351-7357
Published online on: 25 September 2015

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Article Open Access

Gene microarray analyses for potential biomarkers of single and recurrent venous thromboembolism

Wugang Zhou, Ke Zhang, Dongrui Chen, Pingjin Gao, Qiao Wang
Pages: 7358-7366
Published online on: 22 September 2015

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Article Open Access

MicroRNA‑361‑5p suppresses cancer progression by targeting signal transducer and activator of transcription 6 in non‑small cell lung cancer

Yuefeng Ma, Chuanen Bao, Ranran Kong, Xin Xing, Yaya Zhang, Shaomin Li, Wei Zhang, Jiantao Jiang, Jin Zhang, Zhe Qiao, Danjie Zhang, Zhenchuan Ma, Liangzhang Sun, Bin Zhou
Pages: 7367-7373
Published online on: 01 October 2015

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Article Open Access

Effective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms

Wan Zhang, Helene Pelicano, Ran Yin, Junyi Zeng, Tong Wen, Lu Ding, Ruibin Huang
Pages: 7374-7388
Published online on: 25 September 2015

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Article Open Access

MicroRNA‑328 directly targets p21‑activated protein kinase 6 inhibiting prostate cancer proliferation and enhancing docetaxel sensitivity

Chunhui Liu, Lei Zhang, Yeqing Huang, Kai Lu, Tao Tao, Shuqiu Chen, Xiaowen Zhang, Han Guan, Ming Chen, Bin Xu
Pages: 7389-7395
Published online on: 30 September 2015

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Article Open Access

MicroRNA‑144 inhibits migration and proliferation in rectal cancer by downregulating ROCK‑1

Shang‑Dang Cai, Jian‑She Chen, Zuo‑Wu Xi, Long‑Jiang Zhang, Ming‑Liao Niu, Zong‑Yue Gao
Pages: 7396-7402
Published online on: 30 September 2015

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Article Open Access

MicroRNA-590 is an EMT-suppressive microRNA involved in the TGFβ signaling pathway

Tianming Liu, Fang Nie, Xianggui Yang, Xiaoyan Wang, Yue Yuan, Zhongshi Lv, Li Zhou, Rui Peng, Dongsheng Ni, Yuping Gu, Qin Zhou, Yaguang Weng
Pages: 7403-7411
Published online on: 25 September 2015

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Article Open Access

Isoflurane suppresses the self-renewal of normal mouse neural stem cells in a p53-dependent manner by activating the Lkb1-p53-p21 signalling pathway

Lengchen Hou, Te Liu, Jian Wang
Pages: 7412-7418
Published online on: 29 September 2015

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Article

Upregulation of extracellular matrix metalloproteinase inducer promotes hypoxia-induced epithelial-mesenchymal transition in esophageal cancer

Xiaopeng Wu, Bin Qiao, Qin Liu, Weiguo Zhang
Pages: 7419-7424
Published online on: 01 October 2015

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Article

Analysis of the direct injury effector of oligodendroglia cells or myelin sheath in an experimental allergic encephalomyelitis model induced by the MOG35-55 peptide

Xiangyu Zhou, Xiaoyong Li, Meina Feng, Qi Zhang, Zhendong Yang
Pages: 7425-7432
Published online on: 24 September 2015

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Article

Role of microRNA‑503 in the suppression of osteosarcoma cell proliferation and migration via modulation of fibroblast growth factor 2

Bing Wu, Wenzhi Bi
Pages: 7433-7438
Published online on: 30 September 2015

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Article

Neuroepithelial transforming gene 1 functions as a potential prognostic marker for patients with non-small cell lung cancer

Li Fang, Jialiang Zhu, Yuchao Ma, Cao Hong, Sheng Xiao, Longyu Jin
Pages: 7439-7446
Published online on: 29 September 2015

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Article

MicroRNA expression in bone marrow mesenchymal stem cells from mice with steroid-induced osteonecrosis of the femoral head

Bingqing Wang, Peng Yu, Tao Li, Yanyan Bian, Xisheng Weng
Pages: 7447-7454
Published online on: 29 September 2015

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Article Open Access

Gene expression profile analysis of ventilator-associated pneumonia

Xiaoli Xu, Bo Yuan, Quan Liang, Huimin Huang, Xiangyi Yin, Xiaoyue Sheng, Niuyan Nie, Hongmei Fang
Pages: 7455-7462
Published online on: 29 September 2015

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Article

Human umbilical cord mesenchymal stem cells improve the immune‑associated inflammatory and prothrombotic state in collagen type‑Ⅱ‑induced arthritic rats

Jian Gu, Wei Gu, Chuanming Lin, Hao Gu, Wei Wu, Jie Yin, Jun Ni, Xiaoping Pei, Mei Sun, Fangfang Wang, Zou Li, Xinzheng Cai, Minmin Ren, Zhang Yu, Xiang Gu
Pages: 7463-7470
Published online on: 30 September 2015

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Article

Prednisone inhibits the focal adhesion kinase/receptor activator of NF-κB ligand/mitogen-activated protein kinase signaling pathway in rats with adriamycin-induced nephropathy

Minyuan Ye, Jing Zheng, Xiaoying Chen, Xuelan Chen, Xinhong Wu, Xiuqin Lin, Yafang Liu
Pages: 7471-7478
Published online on: 25 September 2015

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Article

Characterization of pancreatic ductal adenocarcinoma using whole transcriptome sequencing and copy number analysis by single-nucleotide polymorphism array

Mariacristina Di Marco, Annalisa Astolfi, Elisa Grassi, Silvia Vecchiarelli, Marina Macchini, Valentina Indio, Riccardo Casadei, Claudio Ricci, Marielda D'Ambra, Giovanni Taffurelli, Carla Serra, Giorgio Ercolani, Donatella Santini, Antonia D'Errico, Antonio Daniele Pinna, Francesco Minni, Sandra Durante, Laura Raffaella Martella, Guido Biasco
Pages: 7479-7484
Published online on: 22 September 2015

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Article

Peripheral blood microRNA-15a is a potential biomarker for type 2 diabetes mellitus and pre-diabetes

Ghada Al‑Kafaji, Ghazi Al‑Mahroos, Nasreen A. Alsayed, Zuheir A. Hasan, Sadia Nawaz, Moiz Bakhiet
Pages: 7485-7490
Published online on: 01 October 2015

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Article

DEK: A novel early screening and prognostic marker for breast cancer

Guo Ying, Yonghui Wu
Pages: 7491-7495
Published online on: 29 September 2015

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Article

Modulation of the expression of sphingosine 1-phosphate 2 receptors regulates the differentiation of pre-adipocytes

Jae‑Kyo Jeong, Myung‑Hee Moon, Sang‑Youel Park
Pages: 7496-7502
Published online on: 29 September 2015

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Article

Expression of glycoprotein nonmetastatic melanoma protein B in macrophages infiltrating injured mucosa is associated with the severity of experimental colitis in mice

Fumisato Sasaki, Kotaro Kumagai, Hirofumi Uto, Yoichiro Takami, Takeshi Kure, Kazuaki Tabu, Yuichro Nasu, Shinichi Hashimoto, Shuji Kanmura, Masatsugu Numata, Akihiro Moriuchi, Toshio Sakiyama, Hirohito Tsubouchi, Akio Ido
Pages: 7503-7511
Published online on: 01 October 2015

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Article

Gene expression profiling of CD133-positive cells in coronary artery disease

Jiayu Li, Changyu Zhou, Jiarui Li, Yingchun Wan, Tao Li, Piyong Ma, Yingjian Wang, Haiyan Sang
Pages: 7512-7516
Published online on: 24 September 2015

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Article

Low-frequency and low-intensity ultrasound-mediated microvessel disruption enhance the effects of radiofrequency ablation on prostate cancer xenografts in nude mice

Yu Yang, Wenkun Bai, Yini Chen, Wei Zhang, Meiwen Wang, Bing Hu
Pages: 7517-7525
Published online on: 28 September 2015

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Rho‑associated kinase inhibitor, Y‑27632, inhibits the invasion and proliferation of T24 and 5367 bladder cancer cells

Lei Jiang, Jiaming Wen, Wei Luo
Pages: 7526-7530
Published online on: 30 September 2015

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Effects of high‑mobility group box 1 knockdown on proliferation, migration and invasion of the HONE‑1 human nasopharyngeal carcinoma cell line

Tao Peng, Min Hu, Tingting Wu, Zhe Chen, Cen Zhang, Shou Huang, Xuhong Zhou
Pages: 7531-7537
Published online on: 30 September 2015

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Knockdown of biglycan expression by RNA interference inhibits the proliferation and invasion of, and induces apoptosis in, the HCT116 colon cancer cell line

Xiaojing Xing, Xiaohu Gu, Tianfei Ma
Pages: 7538-7544
Published online on: 29 September 2015

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Article

Quercetin protects RAW264.7 macrophages from glucosamine-induced apoptosis and lipid accumulation via the endoplasmic reticulum stress pathway

Xiaxia Cai, Lei Bao, Xiaoqian Dai, Ye Ding, Zhaofeng Zhang, Yong Li
Pages: 7545-7553
Published online on: 21 September 2015

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Effect of rutin on spinal cord injury through inhibition of the expression of MIP-2 and activation of MMP-9, and downregulation of Akt phosphorylation

Peng Zhang, Xun Ma
Pages: 7554-7560
Published online on: 24 September 2015

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Epigenetic modifications of histone H3 during the transdifferentiation of Thy-1(+) Lin(‑) bone marrow cells into hepatocytes

Xinxin Liao, Yixin Liao, Yantai Zou, Guanhong Li, Caixian Liao
Pages: 7561-7567
Published online on: 29 September 2015

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Wnt4 signaling is associated with the decrease of proliferation and increase of apoptosis during age-related thymic involution

Tianli Wei, Nannan Zhang, Zhibin Guo, Feng Chi, Yan Song, Xike Zhu
Pages: 7568-7576
Published online on: 21 September 2015

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Article

AKT is translocated to the mitochondria during etoposide-induced apoptosis of HeLa cells

Byoungduck Park, Young‑Tae Je, Kwang‑Hoon Chun
Pages: 7577-7581
Published online on: 28 September 2015

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Article

Orexin-A regulates cell apoptosis in human H295R adrenocortical cells via orexin receptor type 1 through the AKT signaling pathway

Xiaocen Chang, Yuyan Zhao, Shujing Ju, Lei Guo
Pages: 7582-7588
Published online on: 29 September 2015

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Article

Protein kinase C pathway mediates the protective effects of glucagon-like peptide-1 on the apoptosis of islet β-cells

Lihai Zhang, Yuesheng Wang, Jiao Wang, Yinglan Liu, Yanbin Yin
Pages: 7589-7594
Published online on: 24 September 2015

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Article

MG132 proteasome inhibitor upregulates the expression of connexin 43 in rats with adriamycin-induced heart failure

Guiying Chen, Jiyi Zhao, Chunyan Liu, Yina Zhang, Yanping Huo, Lijun Zhou
Pages: 7595-7602
Published online on: 21 September 2015

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Bisdemethoxycurcumin suppresses migration and invasion of highly metastatic 95D lung cancer cells by regulating E-cadherin and vimentin expression, and inducing autophagy

Jinhong Xu, Heping Yang, Xiangdong Zhou, Haijing Wang, Liang Gong, Chunlan Tang
Pages: 7603-7608
Published online on: 24 September 2015

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Article

Catalpol suppresses proliferation and facilitates apoptosis of MCF-7 breast cancer cells through upregulating microRNA-146a and downregulating matrix metalloproteinase-16 expression

Chuan Liu, Fan Wu, Yuanwei Liu, Cong Meng
Pages: 7609-7614
Published online on: 25 September 2015

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Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways

Guijun Song, Yu Li, Lulu Lin, Yunpeng Cao
Pages: 7615-7622
Published online on: 29 September 2015

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Article

Licochalcone C induces apoptosis via B-cell lymphoma 2 family proteins in T24 cells

Penglong Wang, Xuan Yuan, Yan Wang, Hong Zhao, Xiling Sun, Qiusheng Zheng
Pages: 7623-7628
Published online on: 22 September 2015

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Article

Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum

Zeng‑Enni Liang, You‑Jin Yi, Yu‑Tong Guo, Ren‑Cai Wang, Qiu‑Long Hu, Xing‑Yao Xiong
Pages: 7629-7636
Published online on: 22 September 2015

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Tenuifoliside A promotes neurite outgrowth in PC12 cells via the PI3K/AKT and MEK/ERK/CREB signaling pathways

Xiaoxing Liu, Xiaolin Wang, Jun Lu
Pages: 7637-7642
Published online on: 30 September 2015

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Article

Tumor suppressor microRNA-18a regulates tumor proliferation and invasion by targeting TBPL1 in colorectal cancer cells

Guanghui Liu, Yuanhua Liu, Zhen Yang, Junxia Wang, Dongyan Li, Xiefu Zhang
Pages: 7643-7648
Published online on: 17 September 2015

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Article

Cyclooxygenase I and II inhibitors distinctly enhance hippocampal- and cortex-dependent cognitive functions in mice

Huma Syed, Muhammad Faisal Ikram, Ahmed Yaqinuddin, Touqeer Ahmed
Pages: 7649-7656
Published online on: 23 September 2015

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Article

Synergistic topical application of salt-processed Phellodendron amurense and Sanguisorba officinalis Linne alleviates atopic dermatitis symptoms by reducing levels of immunoglobulin E and pro-inflammatory cytokines in NC/Nga mice

Sunmin Park, Da Sol Kim, Suna Kang, Bae Keun Shin
Pages: 7657-7664
Published online on: 22 September 2015

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Additive effects of eukaryotic co‑expression plasmid carrying GRIM‑19 and LKB1 genes on breast cancer in vitro and in vivo Retraction in /10.3892/mmr.2021.12226

Wei Zhang, Ying Shao, Ye Du, Wei Geng, Tong Jiang, Haipeng Liu, Duo Zhang
Pages: 7665-7672
Published online on: 30 September 2015

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Article

Quantitative mRNA expression analysis of selected genes in patients with early-stage hypothyroidism induced by treatment with iodine-131

Kun Guo, Rui Gao, Yan Yu, Weixiao Zhang, Yuxuan Yang, Aimin Yang
Pages: 7673-7680
Published online on: 23 September 2015

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Article

Inhibition of pro-protein convertase subtilisin/kexin type 6 has a protective role against synovitis in a rat model of rheumatoid arthritis

Huiyu Jiang, Lin Wang, Jihong Pan
Pages: 7681-7686
Published online on: 28 September 2015

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Article

Downregulated microRNA-222 is correlated with increased p27Kip1 expression in a double transgenic mouse model of Alzheimer's disease

Xiaoying Wang, Yanfeng Xu, Hua Zhu, Chunmei Ma, Xiaowei Dai, Chuan Qin
Pages: 7687-7692
Published online on: 21 September 2015

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Article

Chrysin inhibits human airway smooth muscle cells proliferation through the extracellular signal‑regulated kinase 1/2 signaling pathway

Jing Yao, Yun‑Shi Zhang, Gan‑Zhu Feng, Qiang Du
Pages: 7693-7698
Published online on: 30 September 2015

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Article

Luteolin‑induced protection of H2O2‑induced apoptosis in PC12 cells and the associated pathway

Peng Lin, Xing‑Han Tian, Yong‑Shang Yi, Wen‑Shi Jiang, Ying‑Jie Zhou, Wen‑Jing Cheng
Pages: 7699-7704
Published online on: 30 September 2015

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Article

Combination of temozolomide and Taxol exerts a synergistic inhibitory effect on Taxol‑resistant glioma cells via inhibition of glucose metabolism

Ding‑Guo Guan, Han‑Min Chen, Sheng‑Fang Liao, Tian‑Zhi Zhao
Pages: 7705-7711
Published online on: 01 October 2015

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Article

Preparation and preliminary application of monoclonal antibodies to the receptor binding region of Clostridium difficile toxin B

Wei Chen, Wen‑En Liu, Yan‑Ming Li, Shan Luo, Yi‑Ming Zhong
Pages: 7712-7720
Published online on: 25 September 2015

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Evaluation of eight reference genes for quantitative polymerase chain reaction analysis in human T lymphocytes co‑cultured with mesenchymal stem cells Corrigendum in /10.3892/mmr.2021.11920

Xiuying Li, Qiwei Yang, Jinping Bai, Yali Xuan, Yimin Wang
Pages: 7721-7727
Published online on: 30 September 2015

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Article

Evaluation of suitable control genes for quantitative polymerase chain reaction analysis of maternal plasma cell-free DNA

Qiwei Yang, Xiuying Li, Hassan Abdellah Ahmed Ali, Shan Yu, Yucheng Zhang, Mei Wu, Sujie Gao, Guanjie Zhao, Zhenwu Du, Guizhen Zhang
Pages: 7728-7734
Published online on: 17 September 2015

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Article

Taspine derivative TAS9 regulates cell growth and metastasis of human hepatocellular carcinoma

Rui Liu, Wenjie Wang, Bingling Dai, Yanping Liu, Yanmin Zhang
Pages: 7735-7741
Published online on: 30 September 2015

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Article

Inhibition of microRNA-9-3p reduces lipid accumulation in HepG2 cells by targeting the expression of sirtuin type 1

Ya‑Nan Sun, Si Li, Yun‑Tao Zhou, Jia Liu, Luo‑Bing Tian, Yan‑Feng Zhen, Hui Fang
Pages: 7742-7748
Published online on: 25 September 2015

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Article

Evaluation of two high-abundance protein depletion kits and optimization of downstream isoelectric focusing

Fanghua Qiu, Tieying Hou, Dehong Huang, Zhifeng Xue, Dongyan Liang, Qiuming Li, Weimiao Lin
Pages: 7749-7755
Published online on: 01 October 2015

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Article

Resveratrol ameliorates oxidative stress and inhibits aquaporin 4 expression following rat cerebral ischemia-reperfusion injury

Weina Li, Changhong Tan, Yi Liu, Xi Liu, Xin Wang, Yuejiang Gui, Lu Qin, Fen Deng, Zhen Yu, Changlin Hu, Lifen Chen
Pages: 7756-7762
Published online on: 25 September 2015

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Transcription factor cyclic adenosine monophosphate responsive element binding protein negatively regulates tumor necrosis factor alpha-induced protein 1 expression

Ning Liu, Ke Wei, Yu Xun, Xiaoxu Yang, Shiquan Gan, Hui Xiao, Ye Xiao, Feng Yan, Guie Xie, Tingting Wang, Yinke Yang, Jian Zhang, Xiang Hu, Shuanglin Xiang
Pages: 7763-7769
Published online on: 17 September 2015

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Article

Promoter methylation is not associated with FLCN irregulation in lung cyst lesions of primary spontaneous pneumothorax

Yibing Ding, Wei Zou, Chengchu Zhu, Haiyan Min, Dehua Ma, Baofu Chen, Minhua Ye, Yanqing Pan, Lei Cao, Yueming Wan, Qiuxiang Zhu, Haizhen Xia, Wenwen Zhang, Ying Feng, Qian Gao, Long Yi
Pages: 7770-7776
Published online on: 21 September 2015

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Article

Accumulation of CD62P during storage of apheresis platelet concentrates and the role of CD62P in transfusion-related acute lung injury

Shan Tong, Haibao Wang, Ting Zhang, Linfeng Chen, Bowei Liu
Pages: 7777-7781
Published online on: 22 September 2015

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Article

Cryptotanshinone suppresses the proliferation and induces the apoptosis of pancreatic cancer cells via the STAT3 signaling pathway

Yuqing Ge, Bo Yang, Zhe Chen, Rubin Cheng
Pages: 7782-7788
Published online on: 28 September 2015

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Article

Anti-allergic effects of sesquiterpene lactones from the root of Aucklandia lappa Decne

Chang‑Seob Seo, Hye‑Sun Lim, Soo‑Jin Jeong, Hyeun‑Kyoo Shin
Pages: 7789-7795
Published online on: 21 September 2015

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Article

Effects of skeletal muscle denervation on the potency of succinylcholine

Hong Wang, Wei Fu, Gang Liu, Shi‑Tong Li
Pages: 7796-7800
Published online on: 30 September 2015

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Article

Exogenous regucalcin suppresses the proliferation of human breast cancer MDA-MB-231 bone metastatic cells in vitro Erratum in /10.3892/mmr.2017.8276

Masayoshi Yamaguchi, Tomiyasu Murata
Pages: 7801-7805
Published online on: 23 September 2015

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Article

Curcumin induces p53-independent necrosis in H1299 cells via a mitochondria-associated pathway

Feie Li, Xi Chen, Bing Xu, Hua Zhou
Pages: 7806-7814
Published online on: 30 September 2015

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Correction Open Access

[Corrigendum] Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma

Liang Chang, Dan Zhao, Hui‑Bin Liu, Qiu‑Shi Wang, Ping Zhang, Chen‑Long Li, Wen‑Zhong Du, Hong‑Jun Wang, Xing Liu, Zhi‑Ren Zhang, Chuan‑Lu Jiang
Pages: 7815-7815
Published online on: 01 October 2015

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CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
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Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
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Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
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Ayman A. Althubity
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Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
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Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

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Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
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Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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