|
1
|
Sokka T: Work disability in early
rheumatoid arthritis. Clin Exp Rheumatol. 21(5 Suppl 31): S71–S74.
2003.
|
|
2
|
Muller-Ladner U, Kriegsmann J, Franklin
BN, Matsumoto S, Geiler T, Gay RE and Gay S: Synovial fibroblasts
of patients with rheumatoid arthritis attach to and invade normal
human cartilage when engrafted into SCID mice. Am J Pathol.
149:1607–1615. 1996.PubMed/NCBI
|
|
3
|
Tolboom TC, van der Helm-van Mil AH,
Nelissen RG, Breedveld FC, Toes RE and Huizinga TW: Invasiveness of
fibroblast-like synoviocytes is an individual patient
characteristic associated with the rate of joint destruction in
patients with rheumatoid arthritis. Arthritis Rheum. 52:1999–2002.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lafyatis R, Remmers EF, Roberts AB, Yocum
DE, Sporn MB and Wilder RL: Anchorage-independent growth of
synoviocytes from arthritic and normal joints: Stimulation by
exogenous platelet-derived growth factor and inhibition by
transforming growth factor-and retinoids. J Clin Invest.
83:1267–1276. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Bartok B and Firestein GS: Fibroblast-like
synoviocytes: Key effector cells in rheumatoid arthritis. Immunol
Rev. 233:233–255. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Holmdahl R, Mo J, Nordling C, Larsson P,
Jansson L, Goldschmidt T, Andersson M and Klareskog L: Collagen
induced arthritis: An experimental model for rheumatoid arthritis
with involvement of both DTH and immune complex mediated
mechanisms. Clin Exp Rheumatol. 7(Suppl 3): S51–S55.
1989.PubMed/NCBI
|
|
7
|
Tolboom TC, Pieterman E, van der Laan WH,
Toes RE, Huidekoper AL, Nelissen RG, Breedveld FC and Huizinga TW:
Invasive properties of fibroblast-like synoviocytes: Correlation
with growth characteristics and expression of MMP-1, MMP-3, and
MMP-10. Ann Rheum Dis. 61:975–980. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Lin H, Ah Kioon MD, Lalou C, Larghero J,
Launay JM, Khatib AM and Cohen-Solal M: Protective role of systemic
furin in immune response-induced arthritis. Arthritis Rheum.
64:2878–2886. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
D'Anjou F, Routhier S, Perreault JP, Latil
A, Bonnel D, Fournier I, Salzet M and Day R: Molecular validation
of PACE4 as a target in prostate cancer. Transl Oncol. 4:157–172.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chang X and Han J: Expression of
peptidylarginine deiminase type 4 (PAD4) in various tumors. Mol
Carcinog. 45:183–196. 2006. View
Article : Google Scholar
|
|
11
|
Malfait AM, Seymour AB, Gao F, Tortorella
MD, Le Graverand-Gastineau MP, Wood LS, Doherty M, Doherty S, Zhang
W and Arden NK: A role for PACE4 in osteoarthritis pain: Evidence
from human genetic association and null mutant phenotype. Ann Rheum
Dis. 71:1042–1048. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
National Research Council: Guide for the
Care and Use of Laboratory Animals. 8th edition. National Academies
Press; Washington, DC: 2011
|
|
13
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta c(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
14
|
Choi HM, Lee YA, Lee SH, Hong SJ, Hahm DH,
Cho SY, Yang HI, Yoo MC and Kim KS: Adiponectin may contribute to
synovitis and joint destruction in rheumatoid arthritis by
stimulating vascular endothelial growth factor, matrix
metalloproteinase-1, and matrix metalloproteinase-13 expression in
fibroblast-like synoviocytes more than proinflammatory mediators.
Arthritis Res Ther. 11:R1612009. View
Article : Google Scholar
|
|
15
|
Mahloogi H, Bassi DE and Klein-Szanto AJ:
Malignant conversion of non-tumorigenic murine skin keratinocytes
over-expressing PACE4. Carcinogenesis. 23:565–572. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mains RE, Berard CA, Denault JB, Zhou A,
Johnson RC and Leduc R: PACE4: A subtilisin-like endoprotease with
unique properties. Biochem J. 321:587–593. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Seidah NG, Chrétien M and Day R: The
family of subtilisin/kexin like pro-protein and pro-hormone
convertases: Divergent or shared functions. Biochimie. 76:197–209.
1994. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lee A, Qiao Y, Grigoriev G, Chen J,
Park-Min KH, Park SH, Ivashkiv LB and Kalliolias GD: Tumor necrosis
factor alpha induces sustained signaling and a prolonged and
unremitting inflammatory response in rheumatoid arthritis synovial
fibroblasts. Arthritis Rheum. 65:928–938. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Feldmann M and Maini RN: Lasker clinical
medical research award: TNF defined as a therapeutic target for
rheumatoid arthritis and other autoimmune diseases. Nat Med.
9:1245–1250. 2003. View
Article : Google Scholar : PubMed/NCBI
|
|
20
|
Joosten LA, Helsen MM, Van deLoo FA and
Van deBerg WB: Anticytokine treatment of established type II
collagen-induced arthritis in DBA/1 mice. A comparative study using
anti-TNF alpha, anti-IL-1 alpha/beta and IL-1Ra. Arthritis Rheum.
39:797–809. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kuan WP, Tam LS, Wong CK, Ko FW, Li T, Zhu
T and Li EK: CXCL 9 and CXCL 10 as sensitive markers of disease
activity in patients with rheumatoid arthritis. J Rheumatol.
37:257–264. 2010. View Article : Google Scholar
|
|
22
|
Kovacevic I, Hu J, Siehoff-Icking A, Opitz
N, Griffin A, Perkins AC, Munn AL, Müller-Esterl W, Popp R, Fleming
I, et al: The F-BAR protein NOSTRIN participates in FGF signal
transduction and vascular development. EMBO J. 31:3309–3322. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Pardo A and Selman M: Matrix
metalloproteases in aberrant fibrotic tissue remodeling. Proc Am
Thorac Soc. 3:383–388. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Hollander AP, Corke KP, Freemont AJ and
Lewis CE: Expression of hypoxia-inducible factor 1alpha by
macrophages in the rheumatoid synovium: Implications for targeting
of therapeutic genes to the inflamed joint. Arthritis Rheum.
44:1540–1544. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Muz B, Khan MN, Kiriakidis S and Paleolog
EM: Hypoxia. The role of hypoxia and HIF-dependent signaling events
in rheumatoid arthritis. Arthritis Res Ther. 11:2012009. View Article : Google Scholar
|
