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Article

MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility

  • Authors:
    • Deyao Wu
    • Xiaobing Niu
    • Huixing Pan
    • Zichun Zhang
    • Yunfeng Zhou
    • Ping Qu
    • Jian Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Urology, The Fourth Affiliated Hospital of Nantong Medical College, Yancheng City No. 1 People's Hospital, Yancheng, Jiangsu 224001, P.R. China
  • Pages: 2287-2292
    |
    Published online on: January 11, 2016
       https://doi.org/10.3892/mmr.2016.4756
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Abstract

MicroRNA-497 (miR-497) has been reported to be downregulated in certain types of cancer, including breast, gastric, endometrial, colorectal and prostate cancer as well as hepatocellular and nasopharyngeal carcinoma. The present study aimed to investigate the underlying mechanism of the tumor suppressor function of miR‑497 in prostate cancer. Following transfection with miR‑497, the DU145 and PC‑3 prostate cancer cell lines were subjected to Transwell migration and invasion assays, western blot analysis and a luciferase assay. It was revealed that miRNA‑497 inhibited the migra­tion and invasion of prostate cancer cells. In addition, is was indicated that miRNA‑497 directly targets hepatoma‑derived growth factor (HDGF) in prostate cancer cells. These results suggested that restoration of miR‑497 and the resulting downregulation of HDFG may represent a promising therapeutic strategy for prostate cancer.
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1 

Wu D, Huang P, Wang L, Zhou Y, Pan H and Qu P: MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer. Mol Med Rep. 8:626–630. 2013.PubMed/NCBI

2 

Siegel R, Ma J, Zou Z and Jemal A: Cancer statistics, 2014. CA Cancer J Clin. 64:9–29. 2014. View Article : Google Scholar : PubMed/NCBI

3 

Mangoni M, Desideri I, Detti B, Bonomo P, Greto D, Paiar F, Simontacchi G, Meattini I, Scoccianti S, Masoni T, et al: Hypofractionation in prostate cancer: Radiobiological basis and clinical appliance. Biomed Res Int. 2014:7813402014. View Article : Google Scholar : PubMed/NCBI

4 

Lafeuille MH, Gravel J, Grittner A, Lefebvre P, Ellis L and McKenzie RS: Real-World corticosteroid utilization patterns in patients with metastatic castration-resistant prostate cancer in 2 large US administrative claims databases. Am Health Drug Benefits. 6:307–316. 2013.

5 

Nelson CJ, Lee JS, Gamboa MC and Roth AJ: Cognitive effects of hormone therapy in men with prostate cancer: A review. Cancer. 113:1097–1106. 2008. View Article : Google Scholar : PubMed/NCBI

6 

Discacciati A and Wolk A: Lifestyle and dietary factors in prostate cancer prevention. Recent Results Cancer Res. 202:27–37. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Lai GY, Giovannucci EL, Pollak MN, Peskoe SB, Stampfer MJ, Willett WC and Platz EA: Association of C-peptide and leptin with prostate cancer incidence in the health professionals follow-up study. Cancer Causes Control. 25:625–632. 2014. View Article : Google Scholar : PubMed/NCBI

8 

Wu J and Yu E: Insulin-like growth factor receptor-1 (IGF-IR) as a target for prostate cancer therapy. Cancer Metastasis Rev. 33:607–617. 2014. View Article : Google Scholar : PubMed/NCBI

9 

Barba M, McCann SE, Schünemann HJ, Stranges S, Fuhrman B, De Placido S, Carruba G, Freudenheim JL, Trevisan M, Russell M, et al: Lifetime total and beverage specific-alcohol intake and prostate cancer risk: A case-control study. Nutr J. 3:232004. View Article : Google Scholar

10 

Joung JG, Kim D, Lee SY, Kang HJ and Kim JH: Integrated analysis of microRNA-target interactions with clinical outcomes for cancers. BMC Med Genomics. 7(Suppl 1): S102014. View Article : Google Scholar : PubMed/NCBI

11 

Garzon R, Pichiorri F, Palumbo T, Visentini M, Aqeilan R, Cimmino A, Wang H, Sun H, Volinia S, Alder H, et al: MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. Oncogene. 26:4148–4157. 2007. View Article : Google Scholar : PubMed/NCBI

12 

Carthew RW and Sontheimer EJ: Origins and Mechanisms of miRNAs and siRNAs. Cell. 136:642–655. 2009. View Article : Google Scholar : PubMed/NCBI

13 

Friedman RC, Farh KK, Burge CB and Bartel DP: Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19:92–105. 2009. View Article : Google Scholar :

14 

Kwak PB, Iwasaki S and Tomari Y: The microRNA pathway and cancer. Cancer Sci. 101:2309–2315. 2010. View Article : Google Scholar : PubMed/NCBI

15 

Oom AL, Humphries BA and Yang C: MicroRNAs: Novel players in cancer diagnosis and therapies. Biomed Res Int. 2014:9594612014. View Article : Google Scholar : PubMed/NCBI

16 

Esquela-Kerscher A and Slack FJ: Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer. 6:259–269. 2006. View Article : Google Scholar : PubMed/NCBI

17 

Calin GA and Croce CM: MicroRNA signatures in human cancers. Nat Rev Cancer. 6:857–866. 2006. View Article : Google Scholar : PubMed/NCBI

18 

Wang L, Li B, Li L and Wang T: MicroRNA-497 suppresses proliferation and induces apoptosis in prostate cancer cells. Asian Pac J Cancer Prev. 14:3499–3502. 2013. View Article : Google Scholar : PubMed/NCBI

19 

Amate P, Huchon C, Dessapt AL, Bensaid C, Medioni J, Le Frère Belda MA, Bats AS and Lécuru FR: Ovarian cancer: SItes of recurrence. Int J Gynecol Cancer. 23:1590–1596. 2013. View Article : Google Scholar : PubMed/NCBI

20 

Martignani E, Miretti S, Accornero P and Baratta M: MiRNAs highlights in stem and cancer cells. Mini Rev Med Chem. 11:1165–1182. 2011. View Article : Google Scholar

21 

Hummel R, Hussey DJ and Haier J: MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types. Eur J Cancer. 46:298–311. 2010. View Article : Google Scholar

22 

Finnerty JR, Wang WX, Hébert SS, Wilfred BR, Mao G and Nelson PT: The miR-15/107 group of microRNA genes: Evolutionary biology, cellular functions and roles in human diseases. J Mol Biol. 402:491–509. 2010. View Article : Google Scholar : PubMed/NCBI

23 

Li D, Zhao Y, Liu C, Chen X, Qi Y, Jiang Y, Zou C, Zhang X, Liu S, Wang X, et al: Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer. Clin Cancer Res. 17:1722–1730. 2011. View Article : Google Scholar : PubMed/NCBI

24 

Xie Y, Wei RR, Huang GL, Zhang MY, Yuan YF and Wang HY: Checkpoint kinase 1 is negatively regulated by miR-497 in hepa-tocellular carcinoma. Med Oncol. 31:8442014. View Article : Google Scholar

25 

Guo J, Miao Y, Xiao B, Huan R, Jiang Z, Meng D and Wang Y: Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J Gastroenterol Hepatol. 24:652–657. 2009. View Article : Google Scholar : PubMed/NCBI

26 

Chen HC, Chen GH, Chen YH, Liao WL, Liu CY, Chang KP, Chang YS and Chen SJ: MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma. Br J Cancer. 100:1002–1011. 2009. View Article : Google Scholar : PubMed/NCBI

27 

Hiroki E, Akahira J, Suzuki F, Nagase S, Ito K, Suzuki T, Sasano H and Yaegashi N: Changes in microRNA expression levels correlate with clinicopathological features and prognoses in endometrial serous adenocarcinomas. Cancer Sci. 101:241–249. 2010. View Article : Google Scholar

28 

Guo ST, Jiang CC, Wang GP, Li YP, Wang CY, Guo XY, Yang RH, Feng Y, Wang FH, Tseng HY, et al: MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. Oncogene. 32:1910–1920. 2013. View Article : Google Scholar :

29 

Shen L, Li J, Xu L, Ma J, Li H, Xiao X, Zhao J and Fang L: MiR-497 induces apoptosis of breast cancer cells by targeting Bcl-w. Exp Ther Med. 3:475–480. 2012.PubMed/NCBI

30 

Zheng D, Radziszewska A and Woo P: MicroRNA 497 modulates interleukin 1 signalling via the MAPK/ERK pathway. FEBS Lett. 586:4165–4172. 2012. View Article : Google Scholar : PubMed/NCBI

31 

Luo M, Shen D, Zhou X, Chen X and Wang W: MicroRNA-497 is a potential prognostic marker in human cervical cancer and functions as a tumor suppressor by targeting the insulin-like growth factor 1 receptor. Surgery. 153:836–847. 2013. View Article : Google Scholar : PubMed/NCBI

32 

Chen X, Yun J, Fei F, Yi J, Tian R, Li S and Gan X: Prognostic value of nuclear hepatoma-derived growth factor (HDGF) localization in patients with breast cancer. Pathol Res Pract. 208:437–443. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Lin YW, Li CF, Chen HY, Yen CY, Lin LC, Huang CC, Huang HY, Wu PC, Chen CH, Chen SC and Tai MH: The expression and prognostic significance of hepatoma-derived growth factor in oral cancer. Oral Oncol. 48:629–635. 2012. View Article : Google Scholar : PubMed/NCBI

34 

Abouzied MM, Baader SL, Dietz F, Kappler J, Gieselmann V and Franken S: Expression patterns and different subcellular localization of the growth factors HDGF (hepatoma-derived growth factor) and HRP-3 (HDGF-related protein-3) suggest functions in addition to their mitogenic activity. Biochem J. 378:169–176. 2004. View Article : Google Scholar

35 

Sedlmaier A, Wernert N, Gallitzendörfer R, Abouzied MM, Gieselmann V and Franken S: Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation. BMC Cancer. 11:4572011. View Article : Google Scholar : PubMed/NCBI

36 

Ren H, Tang X, Lee JJ, Feng L, Everett AD, Hong WK, Khuri FR and Mao L: Expression of hepatoma-derived growth factor is a strong prognostic predictor for patients with early-stage non-small-cell lung cancer. J Clin Oncol. 22:3230–3237. 2004. View Article : Google Scholar : PubMed/NCBI

37 

Hu TH, Huang CC, Liu LF, Lin PR, Liu SY, Chang HW, Changchien CS, Lee CM, Chuang JH and Tai MH: Expression of hepatoma-derived growth factor in hepatocellular carcinoma. Cancer. 98:1444–1456. 2003. View Article : Google Scholar : PubMed/NCBI

38 

Lepourcelet M, Tou L, Cai L, Sawada J, Lazar AJ, Glickman JN, Williamson JA, Everett AD, Redston M, Fox EA, et al: Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development. 132:415–427. 2005. View Article : Google Scholar

39 

Yamamoto S, Makuuchi H, Shimada H, Chino O, Nishi T, Kise Y, Kenmochi T and Hara T: Clinical analysis of reflux esophagitis following esophagectomy with gastric tube reconstruction. J Gastroenterol. 42:342–345. 2007. View Article : Google Scholar : PubMed/NCBI

40 

Uyama H, Tomita Y, Nakamura H, Nakamori S, Zhang B, Hoshida Y, Enomoto H, Okuda Y, Sakon M, Aozasa K, et al: Hepatoma-derived growth factor is a novel prognostic factor for patients with pancreatic cancer. Clin Cancer Res. 12:6043–6048. 2006. View Article : Google Scholar : PubMed/NCBI

41 

Bernard K, Litman E, Fitzpatrick JL, Shellman YG, Argast G, Polvinen K, Everett AD, Fukasawa K, Norris DA, Ahn NG and Resing KA: Functional proteomic analysis of melanoma progression. Cancer Res. 63:6716–6725. 2003.PubMed/NCBI

42 

Okuda Y, Nakamura H, Yoshida K, Enomoto H, Uyama H, Hirotani T, Funamoto M, Ito H, Everett AD and Hada T: Hepatoma-derived growth factor induces tumorigenesis in vivo through both direct angiogenic activity and induction of vascular endothelial growth factor. Cancer Sci. 94:1034–1041. 2003. View Article : Google Scholar : PubMed/NCBI

43 

Matsuyama A, Inoue H, Shibuta K, Tanaka Y, Barnard GF, Sugimachi K and Mori M: Hepatoma-derived growth factor is associated with reduced sensitivity to irradiation in esophageal cancer. Cancer Res. 61:5714–5717. 2001.PubMed/NCBI

44 

Everett AD: Identification, cloning and developmental expression of hepatoma-derived growth factor in the developing rat heart. Dev Dyn. 222:450–458. 2001. View Article : Google Scholar : PubMed/NCBI

45 

Everett AD, Lobe DR, Matsumura ME, Nakamura H and McNamara CA: Hepatoma-derived growth factor stimulates smooth muscle cell growth and is expressed in vascular development. J Clin Invest. 105:567–575. 2000. View Article : Google Scholar : PubMed/NCBI

46 

Oliver JA and Al-Awqati Q: An endothelial growth factor involved in rat renal development. J Clin Invest. 102:1208–1219. 1998. View Article : Google Scholar : PubMed/NCBI

47 

Crossin KL, Tai MH, Krushel LA, Mauro VP and Edelman GM: Glucocorticoid receptor pathways are involved in the inhibition of astrocyte proliferation. Proc Natl Acad Sci USA. 94:2687–2692. 1997. View Article : Google Scholar : PubMed/NCBI

48 

Guo Z, He Y, Wang S, Zhang A, Zhao P, Gao C and Cao B: Various effects of hepatoma-derived growth factor on cell growth, migration and invasion of breast cancer and prostate cancer cells. Oncol Rep. 26:511–517. 2011.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Wu D, Niu X, Pan H, Zhang Z, Zhou Y, Qu P and Zhou J: MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility. Mol Med Rep 13: 2287-2292, 2016.
APA
Wu, D., Niu, X., Pan, H., Zhang, Z., Zhou, Y., Qu, P., & Zhou, J. (2016). MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility. Molecular Medicine Reports, 13, 2287-2292. https://doi.org/10.3892/mmr.2016.4756
MLA
Wu, D., Niu, X., Pan, H., Zhang, Z., Zhou, Y., Qu, P., Zhou, J."MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility". Molecular Medicine Reports 13.3 (2016): 2287-2292.
Chicago
Wu, D., Niu, X., Pan, H., Zhang, Z., Zhou, Y., Qu, P., Zhou, J."MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility". Molecular Medicine Reports 13, no. 3 (2016): 2287-2292. https://doi.org/10.3892/mmr.2016.4756
Copy and paste a formatted citation
x
Spandidos Publications style
Wu D, Niu X, Pan H, Zhang Z, Zhou Y, Qu P and Zhou J: MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility. Mol Med Rep 13: 2287-2292, 2016.
APA
Wu, D., Niu, X., Pan, H., Zhang, Z., Zhou, Y., Qu, P., & Zhou, J. (2016). MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility. Molecular Medicine Reports, 13, 2287-2292. https://doi.org/10.3892/mmr.2016.4756
MLA
Wu, D., Niu, X., Pan, H., Zhang, Z., Zhou, Y., Qu, P., Zhou, J."MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility". Molecular Medicine Reports 13.3 (2016): 2287-2292.
Chicago
Wu, D., Niu, X., Pan, H., Zhang, Z., Zhou, Y., Qu, P., Zhou, J."MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility". Molecular Medicine Reports 13, no. 3 (2016): 2287-2292. https://doi.org/10.3892/mmr.2016.4756
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