|
1
|
Moujalled DM, Cook WD, Murphy JM and Vaux
DL: Necroptosis induced by RIPK3 requires MLKL but not Drp1. Cell
Death Dis. 5:e10862014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Vanden Berghe T, Linkermann A,
Jouan-Lanhouet S, Walczak H and Vandenabeele P: Regulated necrosis:
The expanding network of non-apoptotic cell death pathways. Nat Rev
Mol Cell Biol. 15:135–147. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zhang J and Chan FK: Cell biology. RIPK3
takes another deadly turn. Science. 343:1322–1323. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Liu Q, Qiu J, Liang M, Golinski J, van
Leyen K, Jung JE, You Z, Lo EH, Degterev A and Whalen MJ: Akt and
mTOR mediate programmed necrosis in neurons. Cell Death Dis.
5:e10842014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Tian W, Xu D and Deng YC: Honokiol, a
multifunctional tumor cell death inducer. Pharmazie. 67:811–816.
2012.PubMed/NCBI
|
|
6
|
Li L, Han W, Gu Y, Qiu S, Lu Q, Jin J, Luo
J and Hu X: Honokiol induces a necrotic cell death through the
mitochondrial permeability transition pore. Cancer Res.
67:4894–4903. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Tian W, Deng Y, Li L, He H, Sun J and Xu
D: Honokiol synergizes chemotherapy drugs in multidrug resistant
breast cancer cells via enhanced apoptosis and additional
programmed necrotic death. Int J Oncol. 42:721–732. 2013.
|
|
8
|
Tian W, Xu D, Han W, He H, Cai H, Chen H,
Zhou M, Chen J and Deng YC: Cyclophilin D modulates cell death
transition from early apoptosis to programmed necrosis induced by
honokiol. Int J Oncol. 42:1654–1663. 2013.PubMed/NCBI
|
|
9
|
Remijsen Q, Goossens V, Grootjans S, Van
den Haute C, Vanlangenakker N, Dondelinger Y, Roelandt R, Bruggeman
I, Goncalves A, Bertrand MJ, et al: Depletion of RIPK3 or MLKL
blocks TNF-driven necroptosis and switches towards a delayed RIPK1
kinase-dependent apoptosis. Cell Death Dis. 5:e10042014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Shimobayashi M and Hall MN: Making new
contacts: The mTOR network in metabolism and signalling crosstalk.
Nat Rev Mol Cell Biol. 15:155–162. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yang H, Rudge DG, Koos JD, Vaidialingam B,
Yang HJ and Pavletich NP: mTOR kinase structure, mechanism and
regulation. Nature. 497:217–223. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Beauchamp EM and Platanias LC: The
evolution of the TOR pathway and its role in cancer. Oncogene.
32:3923–3932. 2013. View Article : Google Scholar
|
|
13
|
Hortobagyi GN, Chen D, Piccart M, Rugo HS,
Burris HA III, Pritchard KI, Campone M, Noguchi S, Perez AT, Deleu
I, et al: Correlative analysis of genetic alterations and
everolimus benefit in hormone receptor-positive, human epidermal
growth factor receptor 2-negative advanced breast cancer: Results
from BOLERO-2. J Clin Oncol. 26–Oct;2015.Epub ahead of print.
|
|
14
|
Linkermann A, Bräsen JH, Darding M, Jin
MK, Sanz AB, Heller JO, De Zen F, Weinlich R, Ortiz A, Walczak H,
et al: Two independent pathways of regulated necrosis mediate
ischemia-reperfusion injury. Proc Natl Acad Sci USA.
110:12024–12029. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Baines CP, Kaiser RA, Purcell NH, Blair
NS, Osinska H, Hambleton MA, Brunskill EW, Sayen MR, Gottlieb RA,
Dorn GW, et al: Loss of cyclophilin D reveals a critical role for
mitochondrial permeability transition in cell death. Nature.
434:658–662. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kroemer G, Galluzzi L and Brenner C:
Mitochondrial membrane permeabilization in cell death. Physiol Rev.
87:99–163. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Nakagawa T, Shimizu S, Watanabe T,
Yamaguchi O, Otsu K, Yamagata H, Inohara H, Kubo T and Tsujimoto Y:
Cyclophilin D-dependent mitochondrial permeability transition
regulates some necrotic but not apoptotic cell death. Nature.
434:652–658. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Schinzel AC, Takeuchi O, Huang Z, Fisher
JK, Zhou Z, Rubens J, Hetz C, Danial NN, Moskowitz MA and Korsmeyer
SJ: Cyclophilin D is a component of mitochondrial permeability
transition and mediates neuronal cell death after focal cerebral
ischemia. Proc Natl Acad Sci USA. 102:12005–12010. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Wang H, Sun L, Su L, Rizo J, Liu L, Wang
LF, Wang FS and Wang X: Mixed lineage kinase domain-like protein
MLKL causes necrotic membrane disruption upon phosphorylation by
RIP3. Mol Cell. 54:133–146. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Laplante M and Sabatini DM: mTOR signaling
in growth control and disease. Cell. 149:274–293. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zoncu R, Efeyan A and Sabatini DM: mTOR:
From growth signal integration to cancer, diabetes and ageing. Nat
Rev Mol Cell Biol. 12:21–35. 2011. View
Article : Google Scholar
|
|
22
|
Park EJ, Min HY, Chung HJ, Hong JY, Kang
YJ, Hung TM, Youn UJ, Kim YS, Bae K, Kang SS and Lee SK:
Down-regulation of c-Src/EGFR-mediated signaling activation is
involved in the honokiol-induced cell cycle arrest and apoptosis in
MDA-MB-231 human breast cancer cells. Cancer Lett. 277:133–140.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Nagalingam A, Arbiser JL, Bonner MY,
Saxena NK and Sharma D: Honokiol activates AMP-activated protein
kinase in breast cancer cells via an LKB1-dependent pathway and
inhibits breast carcinogenesis. Breast Cancer Res. 14:R352012.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Crane C, Panner A, Pieper RO, Arbiser J
and Parsa AT: Honokiol-mediated inhibition of PI3K/mTOR pathway: A
potential strategy to overcome immunoresistance in glioma, breast
and prostate carcinoma without impacting T cell function. J
Immunother. 32:585–592. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kaushik G, Ramalingam S, Subramaniam D,
Rangarajan P, Protti P, Rammamoorthy P, Anant S and Mammen JM:
Honokiol induces cytotoxic and cytostatic effects in malignant
melanoma cancer cells. Am J Surg. 204:868–873. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Nogueira V, Park Y, Chen CC, Xu PZ, Chen
ML, Tonic I, Unterman T and Hay N: Akt determines replicative
senescence and oxidative or oncogenic premature senescence and
sensitizes cells to oxidative apoptosis. Cancer Cell. 14:458–470.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kops GJ, Dansen TB, Polderman PE, Saarloos
I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH and Burgering
BM: Forkhead transcription factor FOXO3a protects quiescent cells
from oxidative stress. Nature. 419:316–321. 2002. View Article : Google Scholar : PubMed/NCBI
|
