|
1
|
Bhalerao J and Bowcock AM: The genetics of
psoriasis: A complex disorder of the skin and immune system. Hum
Mol Genet. 7:1537–1545. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Farkas A, Kemény L, Szöny BJ, Bata-Csörgö
Z, Pivarcsi A, Kiss M, Széll M, Koreck A and Dobozy A: Dithranol
upregulates IL-10 receptors on the cultured human keratinocyte cell
line HaCaT. Inflamm Res. 50:44–49. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Koo J and Arain S: Traditional Chinese
medicine for the treatment of dermatologic disorders. Arch
Dermatol. 134:1388–1393. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Tse TW: Use of common Chinese herbs in the
treatment of psoriasis. Clin Exp Dermatol. 28:469–475. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Chen X, Yang L, Oppenheim JJ and Howard
MZ: Cellular pharmacology studies of shikonin derivatives.
Phytother Res. 16:199–209. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kourounakis AP, Assimopoulou AN,
Papageorgiou VP, Gavalas A and Kourounakis PN: Alkannin and
shikonin: Effect on free radical processes and on inflammation - a
preliminary pharmacochemical investigation. Arch Pharm (Weinheim).
335:262–266. 2002. View Article : Google Scholar
|
|
7
|
Hisa T, Kimura Y, Takada K, Suzuki F and
Takigawa M: Shikonin, an ingredient of Lithospermum erythrorhizon,
inhibits angiogenesis in vivo and in vitro. Anticancer Res.
18:783–790. 1998.PubMed/NCBI
|
|
8
|
Xu Y, Xu X, Gao X, Chen H and Geng L:
Shikonin suppresses IL-17-induced VEGF expression via blockage of
JAK2/STAT3 pathway. Int Immunopharmacol. 19:327–333. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Yoon Y, Kim YO, Lim NY, Jeon WK and Sung
HJ: Shikonin, an ingredient of Lithospermum erythrorhizon induced
apoptosis in HL60 human premyelocytic leukemia cell line. Planta
Med. 65:532–535. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Hsu PC, Huang YT, Tsai ML, Wang YJ, Lin JK
and Pan MH: Induction of apoptosis by shikonin through coordinative
modulation of the Bcl-2 family, p27 and p53, release of cytochrome
c, and sequential activation of caspases in human colorectal
carcinoma cells. J Agric Food Chem. 52:6330–6337. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chang IC, Huang YJ, Chiang TI, Yeh CW and
Hsu LS: Shikonin induces apoptosis through reactive oxygen
species/extracellular signal-regulated kinase pathway in
osteosarcoma cells. Biol Pharm Bull. 33:816–824. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Singh F, Gao D, Lebwohl MG and Wei H:
Shikonin modulates cell proliferation by inhibiting epidermal
growth factor receptor signaling in human epidermoid carcinoma
cells. Cancer Lett. 200:115–121. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Gong K and Li W: Shikonin, a Chinese
plant-derived naphthoquinone, induces apoptosis in hepatocellular
carcinoma cells through reactive oxygen species: A potential new
treatment for hepatocellular carcinoma. Free Radic Biol Med.
51:2259–2271. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chen CH, Lin ML, Ong PL and Yang JT: Novel
multiple apoptotic mechanism of shikonin in human glioma cells. Ann
Surg Oncol. 19:3097–3106. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chen CH, Chern CL, Lin CC, Lu FJ, Shih MK,
Hsieh PY and Liu TZ: Involvement of reactive oxygen species, but
not mitochondrial permeability transition in the apoptotic
induction of human SK-Hep-1 hepatoma cells by shikonin. Planta Med.
69:1119–1124. 2003. View Article : Google Scholar
|
|
16
|
Budihardjo I, Oliver H, Lutter M, Luo X
and Wang X: Biochemical pathways of caspase activation during
apoptosis. Annu Rev Cell Dev Biol. 15:269–290. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Elmore S: Apoptosis: A review of
programmed cell death. Toxicol Pathol. 35:495–516. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Kinnally KW, Martinez-Caballero S and
Dejean LM: Detection of the mitochondrial apoptosis-induced channel
(MAC) and its regulation by Bcl-2 family proteins. Curr Protoc
Toxicol Unit. 2:122006.
|
|
19
|
Sun W, Zheng Y, Lu Z, Wang H, Feng Z, Wang
J, Xiao S, Liu F and Liu J: LL-37 attenuates inflammatory
impairment via mTOR signaling-dependent mitochondrial protection.
Int J Biochem Cell Biol. 54:26–35. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Sun W, Zheng Y, Lu Z, Cui Y, Tian Q, Xiao
S, Liu F and Liu J: Overexpression of S100A7 protects LPS-induced
mitochondrial dysfunction and stimulates IL-6 and IL-8 in HaCaT
cells. PLoS One. 9:e929272014. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang Y, Qian RQ and Li PP: Shikonin, an
ingredient of Lithospermum erythrorhizon, down-regulates the
expression of steroid sulfatase genes in breast cancer cells.
Cancer Lett. 284:47–54. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Dejean LM, Martinez-Caballero S, Manon S
and Kinnally KW: Regulation of the mitochondrial apoptosis-induced
channel, MAC, by BCL-2 family proteins. Biochim Biophys Acta.
1762:191–201. 2006. View Article : Google Scholar
|
|
23
|
Belsõ N, Széll M, Pivarcsi A, Kis K,
Kormos B, Kenderessy AS, Dobozy A, Kemény L and Bata-Csörgõ Z:
Differential expression of D-type cyclins in HaCaT keratinocytes
and in psoriasis. J Invest Dermatol. 128:634–642. 2008. View Article : Google Scholar
|
|
24
|
Zhou LL, Lin ZX, Fung KP, Cheng CH, Che
CT, Zhao M, Wu SH and Zuo Z: Celastrol-induced apoptosis in human
HaCaT keratinocytes involves the inhibition of NF-κB activity. Eur
J Pharmacol. 670:399–408. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Marija K and Larisa PM: The pole of
apoptosis in psoriasis and lichen planus. Focus on Cell Apoptosis
Research. Cho DW: Nova Science Publishers, Inc; New York: pp.
233–240. 2007
|
|
26
|
Okada H and Mak TW: Pathways of apoptotic
and non-apoptotic death in tumour cells. Nat Rev Cancer. 4:592–603.
2004. View
Article : Google Scholar : PubMed/NCBI
|
|
27
|
Gross A, Jockel J, Wei MC and Korsmeyer
SJ: Enforced dimerization of BAX results in its translocation,
mitochondrial dysfunction and apoptosis. EMBO J. 17:3878–3885.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Mao X, Yu CR, Li WH and Li WX: Induction
of apoptosis by shikonin through a ROS/JNK-mediated process in
Bcr/Abl-positive chronic myelogenous leukemia (CML) cells. Cell
Res. 18:879–888. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ahn J, Won M, Choi JH, Kim YS, Jung CR, Im
DS, Kyun ML, Lee K, Song KB and Chung KS: Reactive oxygen
species-mediated activation of the Akt/ASK1/p38 signaling cascade
and p21(Cip1) downregulation are required for shikonin-induced
apoptosis. Apoptosis. 18:870–881. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Min R, Tong J, Wenjun Y, Wenhu D, Xiaojian
Z, Jiacai H, Jian Z, Wantao C and Chenping Z: Growth inhibition and
induction of apoptosis in human oral squamous cell carcinoma
Tca-8113 cell lines by Shikonin was partly through the inactivation
of NF-kappaB pathway. Phytother Res. 22:407–415. 2008. View Article : Google Scholar : PubMed/NCBI
|
