|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hirata T, Watanabe M, Kaku H, Kobayashi Y,
Yamada H, Sakaguchi M, Takei K, Huh NH, Nasu Y and Kumon H:
REIC/Dkk-3-encoding adenoviral vector as a potentially effective
therapeutic agent for bladder cancer. Int J Oncol. 41:559–564.
2012.PubMed/NCBI
|
|
3
|
Collier FM, Baker AJ, Walder K, Stupka N,
Martin SD and Kirkland MA: A Rho-GTPase effector, Rhotekin-2
(RTKN2) is associated with BMP8b and IL-16 cytokine expression and
increased sensitivity to apoptosis in lymphocytes. Blood.
110:22932007.
|
|
4
|
Collier FM, Gregorio-King CC, Gough TJ,
Talbot CD, Walder K and Kirkland MA: Identification and
characterization of a lymphocytic Rho-GTPase effector: Rhotekin-2.
Biochem Biophys Res Commun. 324:1360–1369. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Collier FM, Loving A, Baker AJ, McLeod J,
Walder K and Kirkland MA: RTKN2 induces NF-KappaB dependent
resistance to intrinsic apoptosis in HEK cells and regulates BCL-2
genes in human CD4(+) lymphocytes. J Cell Death. 2:9–23.
2009.PubMed/NCBI
|
|
6
|
Dat le T, Matsuo T, Yoshimaru T, Kakiuchi
S, Goto H, Hanibuchi M, Kuramoto T, Nishioka Y, Sone S and Katagiri
T: Identification of genes potentially involved in bone metastasis
by genome-wide gene expression profile analysis of non-small cell
lung cancer in mice. Int J Oncol. 40:1455–1469. 2012.PubMed/NCBI
|
|
7
|
Gregorio-King CC, Gough T, Van Der Meer
GJ, Hosking JB, Waugh CM, McLeod JL, Collier FM and Kirkland MA:
Mechanisms of resistance to the cytotoxic effects of oxysterols in
human leukemic cells. J Steroid Biochem Mol Biol. 88:311–320. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Aupeix K, Weltin D, Mejia JE, Christ M,
Marchal J, Freyssinet JM and Bischoff P: Oxysterol-induced
apoptosis in human monocytic cell lines. Immunobiology.
194:415–428. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ayala-Torres S, Moller PC, Johnson BH and
Thompson EB: Characteristics of 25-hydroxycholesterol-induced
apoptosis in the human leukemic cell line CEM. Exp Cell Res.
235:35–47. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Gregorio-King CC, Collier FM, Bolton KA,
Ferguson M, Hosking JB, Collier GR and Kirkland MA: Effect of
oxysterols on hematopoietic progenitor cells. Exp Hematol.
30:670–678. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Shephard DA: The 1975 Declaration of
Helsinki and consent. Can Med Assoc J. 115:1191–1192.
1976.PubMed/NCBI
|
|
12
|
Payton JE, Grieselhuber NR, Chang LW,
Murakami M, Geiss GK, Link DC, Nagarajan R, Watson MA and Ley TJ:
High throughput digital quantification of mRNA abundance in primary
human acute myeloid leukemia samples. J Clin Invest. 119:1714–1726.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
13
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
14
|
Yin TY, Hsiao YW, Peng WH, Wang MJ and
Chen JY: Overexpression of Rhotekin confers gastric cancer cells
resistance to interferon-{alpha}-mediated growth inhibition. Cancer
Res. 72:44352012. View Article : Google Scholar
|
|
15
|
Myouzen K, Kochi Y, Okada Y, Terao C,
Suzuki A, Ikari K, Tsunoda T, Takahashi A, Kubo M, Taniguchi A, et
al: Functional variants in NFKBIE and RTKN2 involved in activation
of the NF-κB pathway are associated with rheumatoid arthritis in
Japanese. PLoS Genet. 8:e10029492012. View Article : Google Scholar
|
|
16
|
Li W, Wu YF, Xu RH, Lu H, Hu C and Qian H:
miR-1246 releases RTKN2-dependent resistance to UVB-induced
apoptosis in HaCaT cells. Mol Cell Biochem. 394:299–306. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Gregorio-King C, Gough T, Collier F and
Kirkland M: RTKN2-A novel gene differentially expressed in CD34+
cells from umbilical cord blood, normal and AML bone marrow. Exp
Hematol. 31:206–207. 2003.
|
|
18
|
Wang S, Bian C, Yang Z, Bo Y, Li J, Zeng
L, Zhou H and Zhao RC: miR-145 inhibits breast cancer cell growth
through RTKN. Int J Oncol. 34:1461–1466. 2009.PubMed/NCBI
|
|
19
|
Sevli S, Uzumcu A, Solak M, Ittmann M and
Ozen M: The function of microRNAs, small but potent molecules, in
human prostate cancer. Prostate Cancer Prostatic Dis. 13:208–217.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Malumbres M and Barbacid M: Mammalian
cyclin-dependent kinases. Trends Biochem Sci. 30:630–641. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Massagué J: G1 cell-cycle control and
cancer. Nature. 432:298–306. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
van den Heuvel S and Harlow E: Distinct
roles for cyclin-dependent kinases in cell cycle control. Science.
262:2050–2054. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Tetsu O and McCormick F: Proliferation of
cancer cells despite CDK2 inhibition. Cancer Cell. 3:233–245. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Piatti S, Lengauer C and Nasmyth K: Cdc6
is an unstable protein whose de novo synthesis in G1 is important
for the onset of S phase and for preventing a 'reductional'
anaphase in the budding yeast Saccharomyces cerevisiae. EMBO J.
14:3788–3799. 1995.PubMed/NCBI
|
|
25
|
Zwerschke W, Rottjakob HW and Küntzel H:
The Saccharomyces cerevisiae CDC6 gene is transcribed at late
mitosis and encodes a ATP/GTPase controlling S phase initiation. J
Biol Chem. 269:23351–23356. 1994.PubMed/NCBI
|
|
26
|
Feng D, Tu Z, Wu W and Liang C: Inhibiting
the expression of DNA replication-initiation proteins induces
apoptosis in human cancer cells. Cancer Res. 63:7356–7364.
2003.PubMed/NCBI
|
|
27
|
Lau E, Zhu C, Abraham RT and Jiang W: The
functional role of Cdc6 in S-G2/M in mammalian cells. EMBO Rep.
7:425–430. 2006.PubMed/NCBI
|
|
28
|
Perona R, Moncho-Amor V, Machado-Pinilla
R, Belda-Iniesta C and Sánchez Pérez I: Role of CHK2 in cancer
development. Clin Transl Oncol. 10:538–542. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Merchant AM, Kawasaki Y, Chen Y, Lei M and
Tye BK: A lesion in the DNA replication initiation factor Mcm10
induces pausing of elongation forks through chromosomal replication
origins in Saccharomyces cerevisiae. Mol Cell Biol. 17:3261–3271.
1997. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Izumi M, Yatagai F and Hanaoka F: Cell
cycle-dependent proteolysis and phosphorylation of human Mcm10. J
Biol Chem. 276:48526–48531. 2001.PubMed/NCBI
|
|
31
|
Hong Y and Stambrook PJ: Restoration of an
absent G1 arrest and protection from apoptosis in embryonic stem
cells after ionizing radiation. Proc Natl Acad Sci USA.
101:14443–14448. 2004. View Article : Google Scholar : PubMed/NCBI
|
