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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2016 Volume 13 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Lipid droplet-associated proteins in atherosclerosis (Review)

Janeesh Plakkal Ayyappan, Antoni Paul, Young‑Hwa Goo
Pages: 4527-4534
Published online on: 11 April 2016

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Article Open Access

Identification of microRNA-mRNA interactions in atrial fibrillation using microarray expression profiles and bioinformatics analysis

Tao Wang, Bin Wang
Pages: 4535-4540
Published online on: 12 April 2016

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Article Open Access

Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration Retraction in /10.3892/mmr.2021.12100

Jing‑Fang Hong, Ying‑Fang Song, Zheng Liu, Zhao‑Cong Zheng, Hong‑Jie Chen, Shou‑Sen Wang
Pages: 4541-4548
Published online on: 12 April 2016

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Article Open Access

Urinary microRNA-based signature improves accuracy of detection of clinically relevant prostate cancer within the prostate-specific antigen grey zone

Alberto Ivan Salido‑Guadarrama, Jorge Gustavo Morales‑Montor, Claudia Rangel‑Escareño, Elizabeth Langley, Oscar Peralta‑Zaragoza, Jose Luis Cruz Colin, Mauricio Rodriguez‑Dorantes
Pages: 4549-4560
Published online on: 08 April 2016

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Article Open Access

Effects of Per2 overexpression on growth inhibition and metastasis, and on MTA1, nm23-H1 and the autophagy-associated PI3K/PKB signaling pathway in nude mice xenograft models of ovarian cancer

Zhaoxia Wang, Li Li, Yang Wang
Pages: 4561-4568
Published online on: 13 April 2016

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Article Open Access

Cannabinoid WIN‑55,212‑2 mesylate inhibits ADAMTS‑4 activity in human osteoarthritic articular chondrocytes by inhibiting expression of syndecan‑1

Ying Kong, Wanchun Wang, Changjie Zhang, Yi Wu, Yang Liu, Xiaorong Zhou
Pages: 4569-4576
Published online on: 15 April 2016

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Article Open Access

DNase I aggravates islet β-cell apoptosis in type 2 diabetes

Bin Zhu, Lei Zhang, Yue-Ying Zhang, Lei Wang, Xin‑Gang Li, Teng Liu, Yu‑Ke Fu, Yan‑Fei Zheng, Ping Li, Zhi‑Gang Zhao
Pages: 4577-4584
Published online on: 11 April 2016

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Article Open Access

NQDI-1, an inhibitor of ASK1 attenuates acute perinatal hypoxic-ischemic cerebral injury by modulating cell death

Hu Hao, Sitao Li, Hui Tang, Bingqing Liu, Yao Cai, Congcong Shi, Xin Xiao
Pages: 4585-4592
Published online on: 13 April 2016

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Article Open Access

Thrombosis recanalization by paeoniflorin through the upregulation of urokinase‑type plasminogen activator via the MAPK signaling pathway

Songshan Ye, Bingyu Mao, Lei Yang, Weiyun Fu, Junran Hou
Pages: 4593-4598
Published online on: 15 April 2016

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Article Open Access

Comparison of molecular mechanisms of rheumatoid arthritis and osteoarthritis using gene microarrays

Hongqiang Li, Zhenyong Hao, Liqiang Zhao, Wei Liu, Yanlong Han, Yunxing Bai, Jian Wang
Pages: 4599-4605
Published online on: 15 April 2016

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Article Open Access

Downregulation of RUNX3 moderates the frequency of Th17 and Th22 cells in patients with psoriasis

Dandan Fu, Xiangfeng Song, Hua Hu, Min Sun, Zhanguo Li, Zhongwei Tian
Pages: 4606-4612
Published online on: 12 April 2016

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Article Open Access

Hyperoside protects human primary melanocytes against H2O2-induced oxidative damage

Bin Yang, Qin Yang, Xin Yang, Hong‑Bo Yan, Qi‑Ping Lu
Pages: 4613-4619
Published online on: 12 April 2016

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Article Open Access

Circulating microRNAs as biomarkers for the early diagnosis of childhood tuberculosis infection

Mengyao Zhou, Guangyuan Yu, Xiantao Yang, Chaomin Zhu, Zhenzhen Zhang, Xue Zhan
Pages: 4620-4626
Published online on: 08 April 2016

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Article Open Access

Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats

Lianqun Jia, Nan Song, Guanlin Yang, Yixin Ma, Xuetao Li, Ren Lu, Huimin Cao, Ni Zhang, Meilin Zhu, Junyan Wang, Xue Leng, Yuan Cao, Ying Du, Yue Xu
Pages: 4627-4635
Published online on: 14 April 2016

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Article Open Access

Spot14/Spot14R expression may be involved in MSC adipogenic differentiation in patients with adolescent idiopathic scoliosis

Qifei Wang, Junlin Yang, Xiang Lin, Zifang Huang, Chaofan Xie, Hengwei Fan
Pages: 4636-4642
Published online on: 12 April 2016

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Article Open Access

A serum microRNA signature as a prognostic factor for patients with advanced NSCLC and its association with tissue microRNA expression profiles Corrigendum in /10.3892/mmr.2021.12046

Jing Guo, Rui Meng, Zhongyuan Yin, Pengcheng Li, Rui Zhou, Sheng Zhang, Xiaorong Dong, Li Liu, Gang Wu
Pages: 4643-4653
Published online on: 13 April 2016

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Article Open Access

Treatment of experimental autoimmune uveoretinitis with different natural compounds

Man Li, Xiaoming Chen, Juanjuan Liu, Dongmei Wang, Lu Gan, Xin Lv, Yu Qiao
Pages: 4654-4658
Published online on: 08 April 2016

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Article

Tumorigenesis of nuclear transfer-derived embryonic stem cells is reduced through differentiation and enrichment following transplantation in the infarcted rat heart

Qiang Fu, Dechun Su, Ke Wang, Yingjun Zhao
Pages: 4659-4665
Published online on: 07 April 2016

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Article

Geranylgeranylacetone alleviates radiation-induced lung injury by inhibiting epithelial-to-mesenchymal transition signaling

Joong‑Sun Kim, Yeonghoon Son, Myung‑Gu Jung, Ye Ji Jeong, Sung‑Ho Kim, Su‑Jae Lee, Yoon‑Jin Lee, Hae‑June Lee
Pages: 4666-4670
Published online on: 13 April 2016

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Article

Metformin induces apoptosis by microRNA-26a-mediated downregulation of myeloid cell leukaemia-1 in human oral cancer cells

Fang Wang, Jincheng Xu, Hao Liu, Zhe Liu, Fei Xia
Pages: 4671-4676
Published online on: 15 April 2016

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Article

An R1632C variant in the SCN5A gene causing Brugada syndrome

Esperanza García‑Molina, María Sabater‑Molina, Carmen Muñoz, Francisco Ruiz‑Espejo, Juan R. Gimeno
Pages: 4677-4680
Published online on: 11 April 2016

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Article

Apoptotic effects of extract from Cnidium monnieri (L.) Cusson by adenosine monosphosphate-activated protein kinase-independent pathway in HCT116 colon cancer cells

Eun Gyeong Lim, Guen Tae Kim, Se Hee Lee, Sang‑Yong Kim, Young Min Kim
Pages: 4681-4688
Published online on: 13 April 2016

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Article Open Access

Calcitonin gene-related peptide promotes the expression of osteoblastic genes and activates the WNT signal transduction pathway in bone marrow stromal stem cells

Ri Zhou, Zhi Yuan, Jierong Liu, Jian Liu
Pages: 4689-4696
Published online on: 13 April 2016

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Article

Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via its antioxidant, anti‑inflammatory, and anti‑apoptotic activities

Chengmei Long, Jinran Yang, Hua Yang, Xinchang Li, Gongxian Wang
Pages: 4697-4704
Published online on: 14 April 2016

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Article

Herbal medicine Gan‑fu‑kang downregulates Wnt/Ca2+ signaling to attenuate liver fibrogenesis in vitro and in vivo

Yujie Jia, Lijun Yuan, Tingting Xu, Hanshu Li, Guang Yang, Miaona Jiang, Caihua Zhang, Cong Li
Pages: 4705-4714
Published online on: 15 April 2016

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Article

Propofol depresses cisplatin cytotoxicity via the inhibition of gap junctions

Yuan Zhang, Xiyan Wang, Qin Wang, Hui Ge, Liang Tao
Pages: 4715-4720
Published online on: 13 April 2016

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Article

LIF and LIF‑R expression in the endometrium of fertile and infertile women: A prospective observational case‑control study

Chrysoula Margioula‑Siarkou, Yannis Prapas, Stamatios Petousis, Stefanos Milias, Konstantinos Ravanos, Ioannis Kalogiannidis, George Mavromatidis, Constantinos Haitoglou, Nikolaos Prapas, David Rousso
Pages: 4721-4728
Published online on: 15 April 2016

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Article

Ampelopsin suppresses TNF-α-induced migration and invasion of U2OS osteosarcoma cells

Changying Liu, Pengfei Zhao, Yubao Yang, Xiaodong Xu, Liang Wang, Bo Li
Pages: 4729-4736
Published online on: 13 April 2016

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Article

Novel synergic antidiabetic effects of Astragalus polysaccharides combined with Crataegus flavonoids via improvement of islet function and liver metabolism

Kai Cui, Shaobo Zhang, Xin Jiang, Weidong Xie
Pages: 4737-4744
Published online on: 15 April 2016

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Article

Psoralen reverses the P-glycoprotein-mediated multidrug resistance in human breast cancer MCF-7/ADR cells

Jingru Jiang, Xiaohong Wang, Kai Cheng, Wanzhong Zhao, Yitong Hua, Chengfeng Xu, Zhenlin Yang
Pages: 4745-4750
Published online on: 08 April 2016

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Article

Artemisia capillaris formula inhibits hepatic steatosis via an miR‑122‑induced decrease in fatty acid synthase expression in vivo and in vitro

Liya Liu, Jinyan Zhao, Ying Li, Yun Wan, Jiumao Lin, Aling Shen, Wei Xu, Huang Li, Yuchen Zhang, Jianfeng Xu, Jun Peng, Zhenfeng Hong
Pages: 4751-4758
Published online on: 14 April 2016

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Article

Hedgehog gene polymorphisms are associated with the risk of Hirschsprung's disease and anorectal malformation in a Chinese population

Hong Gao, Dajia Wang, Yuzuo Bai, Juan Zhang, Mei Wu, Jie Mi, Huimin Jia, Weilin Wang
Pages: 4759-4766
Published online on: 15 April 2016

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Article

MicroRNA-205 suppresses the invasion and epithelial-mesenchymal transition of human gastric cancer cells

Chang Xu, Ming'e Li, Lin Zhang, Yueyang Bi, Peiyuan Wang, Jun Li, Xingyue Jiang
Pages: 4767-4773
Published online on: 13 April 2016

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Article

Src/STAT3 signaling pathways are involved in KAI1-induced downregulation of VEGF-C expression in pancreatic cancer

Xu Liu, Xiaozhong Guo, Hongyu Li, Jiang Chen, Xingshun Qi
Pages: 4774-4778
Published online on: 07 April 2016

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Article

Ursolic acid protects against ulcerative colitis via anti-inflammatory and antioxidant effects in mice

Baohai Liu, Xuehua Piao, Lianyi Guo, Shanshan Liu, Fang Chai, Leming Gao
Pages: 4779-4785
Published online on: 07 April 2016

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Article

Overexpression of PDZK1IP1, EEF1A2 and RPL41 genes in intrahepatic cholangiocarcinoma

Guanghua Yang, Huajie Zong
Pages: 4786-4790
Published online on: 12 April 2016

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Article

Integration of gene expression and DNA methylation profiles provides a molecular subtype for risk assessment in atherosclerosis Corrigendum in /10.3892/mmr.2016.5915

Sheng‑Chao Ma, Hui‑Ping Zhang, Fan‑Qi Kong, Hui Zhang, Cheng Yang, Yang‑Yang He, Yan‑Hua Wang, An‑Ning Yang, Ju Tian, Xiao‑Ling Yang, Ming‑Hao Zhang, Hua Xu, Yi‑Deng Jiang, Zheng Yu
Pages: 4791-4799
Published online on: 13 April 2016

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Article

MicroRNA-22 is downregulated in clear cell renal cell carcinoma, and inhibits cell growth, migration and invasion by targeting PTEN

Wenxing Fan, Jie Huang, Hua Xiao, Zhang Liang
Pages: 4800-4806
Published online on: 11 April 2016

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Article

Role of peroxiredoxin 2 in H2O2‑induced oxidative stress of primary Leydig cells

Ting Duan, Kai Fan, Shengrong Chen, Qi Yao, Rong Zeng, Zhiwei Hong, Longping Peng, Yong Shao, Bing Yao
Pages: 4807-4813
Published online on: 15 April 2016

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Article

Tetrandrine ameliorates sevoflurane‑induced cognitive impairment via the suppression of inflammation and apoptosis in aged rats

Hongmei Ma, Li Yao, Ling Pang, Xingwei Li, Qun Yao
Pages: 4814-4820
Published online on: 14 April 2016

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Article

Sequence analysis of the L protein of the Ebola 2014 outbreak: Insight into conserved regions and mutations

Gohar Ayub, Yasir Waheed
Pages: 4821-4826
Published online on: 15 April 2016

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Article

Upregulation of microRNA‑337 promotes the proliferation of endometrial carcinoma cells via targeting PTEN

Yangyang Cai, Tao He, Lidan Liang, Xin Zhang, Hongying Yuan
Pages: 4827-4834
Published online on: 15 April 2016

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Article

Continuous evaluation of changes in the serum proteome from early to late stages of sepsis caused by Klebsiella pneumoniae

Swathi Raju M, Jahnavi V, Ratnakar S. Kamaraju, Venkataraman Sritharan, Karthik Rajkumar, Sumathi Natarajan, Anil D. Kumar, Sandeepta Burgula
Pages: 4835-4844
Published online on: 12 April 2016

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Article

Knockdown by shRNA identifies SLC44A5 as a potential therapeutic target in hepatocellular carcinoma

Gui‑Zhu Peng, Qi‑Fa Ye, Ren Wang, Ming‑Xia Li, Zi‑Xuan Yang
Pages: 4845-4852
Published online on: 15 April 2016

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Article

Paeonol enhances thrombus recanalization by inducing vascular endothelial growth factor 165 via ERK1/2 MAPK signaling pathway

Songshan Ye, Xianjuan Liu, Bingyu Mao, Lei Yang, Nuan Liu
Pages: 4853-4858
Published online on: 15 April 2016

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Article

The downregulation of miR‑125a‑5p functions as a tumor suppressor by directly targeting MMP‑11 in osteosarcoma

Niyazi Waresijiang, Jungang Sun, Rewuti Abuduaini, Tayier Jiang, Wenzheng Zhou, Hong Yuan
Pages: 4859-4864
Published online on: 15 April 2016

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Article

Knockdown of Rhotekin 2 expression suppresses proliferation and invasion and induces apoptosis in hepatocellular carcinoma cells

Wei Wei, Huabing Chen, Sibin Liu
Pages: 4865-4871
Published online on: 13 April 2016

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Article

Silencing of RTKN2 by siRNA suppresses proliferation, and induces G1 arrest and apoptosis in human bladder cancer cells Retraction in /10.3892/mmr.2024.13258

Yi‑Xiang Liao, Jin‑Min Zeng, Jia‑Jie Zhou, Guang‑Hua Yang, Kun Ding, Xian‑Jue Zhang
Pages: 4872-4878
Published online on: 14 April 2016

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Article

A novel approach to understanding the role of polymorphic forms of the NR3C1 and TGF-β1 genes in the modulation of the expression of IL-5 and IL-15 mRNA in asthmatic inflammation

Michał Panek, Mateusz Jonakowski, Jan Zioło, Łukasz Wieteska, Beata Małachowska, Tadeusz Pietras, Janusz Szemraj, Piotr Kuna
Pages: 4879-4887
Published online on: 12 April 2016

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Article

LXR agonist T0901317 upregulates thrombomodulin expression in glomerular endothelial cells by inhibition of nuclear factor‑κB

Hanlu Ding, Yi Li, Yunlin Feng, Jin Chen, Xiang Zhong, Nan Wang, Wei Wang, Ping Zhang, Li Wang
Pages: 4888-4896
Published online on: 15 April 2016

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Article

MicroRNA-15b suppresses the growth and invasion of glioma cells through targeted inhibition of cripto-1 expression

Guan Sun, Shu‑Shan Yan, Lei Shi, Zheng‑Qiang Wan, Nan Jiang, Lin‑Shan Fu, Min Li, Jun Guo
Pages: 4897-4903
Published online on: 14 April 2016

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Article

Ginsenoside Rg1 ameliorates hippocampal long-term potentiation and memory in an Alzheimer's disease model

Fengling Li, Xiqing Wu, Jing Li, Qingliang Niu
Pages: 4904-4910
Published online on: 12 April 2016

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Article

The herbal extract KCHO-1 exerts a neuroprotective effect by ameliorating oxidative stress via heme oxygenase-1 upregulation

Dong‑Sung Lee, Wonmin Ko, Bong‑Keun Song, Ilhong Son, Dong‑Woung Kim, Dae‑Gil Kang, Ho‑Sub Lee, Hyuncheol Oh, Jun‑Hyeog Jang, Youn‑Chul Kim, Sungchul Kim
Pages: 4911-4919
Published online on: 14 April 2016

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Article

Integrative analysis of gene expression associated with epilepsy in human epilepsy and animal models

Hengling Chen, Guozheng Xu, Hao Du, Minhan Yi, Chenhong Li
Pages: 4920-4926
Published online on: 13 April 2016

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Article

16α, 17α-epoxypregnenolone-20-oxime inhibits NO and IL-6 production in LPS-treated RAW264.7 cells

Hu‑Nan Sun, Ying‑Hao Han, Li Feng, Cheng‑Hao Jin, Bing Han, Lei Liu, Dong‑Soek Lee, Tea‑Ho Kwon, Le‑Gong Li, Wen‑Zhong Ge, Yu‑Dong Cui
Pages: 4927-4933
Published online on: 14 April 2016

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Article

Bruton's tyrosine kinase inhibitor restrains Wnt signaling in chronic lymphocytic leukemia

Pei‑Pei Li, Kang Lu, Ling‑Yun Geng, Xiang‑Xiang Zhou, Xin‑Yu Li, Xin Wang
Pages: 4934-4938
Published online on: 12 April 2016

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Retraction Open Access

[Retracted] Retinoic acid‑incorporated glycol chitosan nanoparticles inhibit the expression of Ezh2 in U118 and U138 human glioma cells

Hu‑Chen Lu, Jun Ma, Zong Zhuang, Yao Zhang, Hui‑Lin Cheng, Ji‑Xin Shi
Pages: 4939-4939
Published online on: 14 April 2016

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Review

Critical role of oncogenic KRAS in pancreatic cancer (Review)

Jiang Liu, Shunrong Ji, Chen Liang, Yi Qin, Kaizhou Jin, Dingkon Liang, Wenyan Xu, Si Shi, Bo Zhang, Liang Liu, Chen Liu, Jin Xu, Quanxing Ni, Xianjun Yu
Pages: 4943-4949
Published online on: 27 April 2016

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Article Open Access

Microsatellite polymorphism in the P1 promoter region of the IGF‑1 gene is associated with endometrial cancer

Wojciech Kwasniewski, Anna Gozdzicka‑Jozefiak, Maria Wolun‑Cholewa, Grzegorz Polak, Jadwiga Sierocinska‑Sawa, Anna Kwasniewska, Jan Kotarski
Pages: 4950-4958
Published online on: 25 April 2016

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Article Open Access

Effects of tripterygium glycosides on restenosis following endovascular treatment

Bing Han, Chang‑Qing Ge, Hong‑Guang Zhang, Chen‑Guang Zhou, Guo‑Hui Ji, Zheng Yang, Liang Zhang
Pages: 4959-4968
Published online on: 20 April 2016

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Identification of TLR2 and TLR4‑induced microRNAs in human mesenchymal stem cells and their possible roles in regulating TLR signals

Xingbing Wang, Yunxia Zhu, Bo Xu, Jing Wang, Xin Liu
Pages: 4969-4980
Published online on: 27 April 2016

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Effects of ophiopogonin B on the proliferation and apoptosis of SGC‑7901 human gastric cancer cells

Weiyue Zhang, Qiaoyan Zhang, Yiping Jiang, Feng Li, Hailiang Xin
Pages: 4981-4986
Published online on: 27 April 2016

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CXCL12/CXCR4 axis regulates neovascularization and lymphangiogenesis in sutured corneas in mice

Ling‑Ling Du, Ping Liu
Pages: 4987-4994
Published online on: 25 April 2016

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Upregulation of TRPM7 augments cell proliferation and interleukin-8 release in airway smooth muscle cells of rats exposed to cigarette smoke

Xiaoling Lin, Cheng Yang, Linjie Huang, Ming Chen, Jianting Shi, Lihua Ouyang, Tiantian Tang, Wei Zhang, Yiqun Li, Ruiyun Liang, Shanping Jiang
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Published online on: 22 April 2016

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Knockdown of versican V1 induces a severe inflammatory response in LPS-induced acute lung injury via the TLR2-NF-κB signaling pathway in C57BL/6J mice

Lulu Xu, Tao Xue, Jing Zhang, Jieming Qu
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Published online on: 22 April 2016

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Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model

Wei Lu, Lin Wang, Chunxin Wo, Jing Yao
Pages: 5013-5020
Published online on: 22 April 2016

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P‑selectin increases angiotensin II‑induced cardiac inflammation and fibrosis via platelet activation

Gaizhen Liu, Bin Liang, Xiaosu Song, Rui Bai, Weiwei Qin, Xu Sun, Yan Lu, Yunfei Bian, Chuanshi Xiao
Pages: 5021-5028
Published online on: 25 April 2016

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MicroRNA-126 inhibits tumor cell invasion and metastasis by downregulating ROCK1 in renal cell carcinoma

Gui‑Ming Zhang, Lei Luo, Xue‑Mei Ding, Da‑Hai Dong, Bin Li, Xiao‑Cheng Ma, Li‑Jiang Sun
Pages: 5029-5036
Published online on: 22 April 2016

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Sequential changes of endoplasmic reticulum stress and apoptosis in myocardial fibrosis of diabetes mellitus-induced rats

Qiong Yang, Huikuan Gao, Ruiqing Dong, Yong‑Quan Wu
Pages: 5037-5044
Published online on: 25 April 2016

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Trichostatin A potentiates genistein-induced apoptosis and reverses EMT in HEp2 cells

Ruixia Du, Zhe Liu, Xuedong Hou, Gongbi Fu, Ning An, Liping Wang
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Published online on: 28 April 2016

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Transplantation of ovarian granulosa‑like cells derived from human induced pluripotent stem cells for the treatment of murine premature ovarian failure

Te Liu, Qiong Li, Suwei Wang, Chuan Chen, Jin Zheng
Pages: 5053-5058
Published online on: 26 April 2016

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Preparation and performance of a pH-sensitive cisplatin-loaded magnetic nanomedicine that targets tumor cells via folate receptor mediation

Shuai‑Jun Chen, Hong‑Zheng Zhang, Liang‑Cai Wan, Shan‑Shan Jiang, Yi‑Ming Xu, Fang Liu, Tao Zhang, Dong Ma, Min‑Qiang Xie
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Published online on: 21 April 2016

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Production of interleukin‑4 in CD133+ cervical cancer stem cells promotes resistance to apoptosis and initiates tumor growth Retraction in /10.3892/mmr.2016.5732

Chun‑Tao Liu, Ying Xin, Chun‑Yan Tong, Bing Li, Hong‑Li Bao, Cai‑Yun Zhang, Xue‑Hui Wang
Pages: 5068-5076
Published online on: 27 April 2016

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Post-translational modifications of α-synuclein contribute to neurodegeneration in the colon of elderly individuals

Qi Xuan, Yu‑Xian Zhang, Dian‑Gang Liu, Piu Chan, Sheng‑Li Xu, Ye‑Qing Cui
Pages: 5077-5083
Published online on: 22 April 2016

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Quantitative analysis of gene expression in fixed colorectal carcinoma samples as a method for biomarker validation

Beata Ostasiewicz, Paweł Ostasiewicz, Kamila Duś‑Szachniewicz, Katarzyna Ostasiewicz, Piotr Ziółkowski
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Published online on: 27 April 2016

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Simvastatin ameliorates ventricular remodeling via the TGF‑β1 signaling pathway in rats following myocardial infarction

Xiangbin Xiao, Guanglei Chang, Jian Liu, Guangyun Sun, Li Liu, Shu Qin, Dongying Zhang
Pages: 5093-5101
Published online on: 25 April 2016

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Effects of p53 on aldosterone-induced mesangial cell apoptosis in vivo and in vitro

Huimin Shi, Aiqing Zhang, Yanfang He, Min Yang, Weihua Gan
Pages: 5102-5108
Published online on: 21 April 2016

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Chronic effects of soft drink consumption on the health state of Wistar rats: A biochemical, genetic and histopathological study

Adel Alkhedaide, Mohamed Mohamed Soliman, Alaa‑Eldin Salah‑Eldin, Tamer Ahmed Ismail, Zafer Saad Alshehiri, Hossam Fouad Attia
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Published online on: 27 April 2016

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Paclitaxel inhibits selenoprotein S expression and attenuates endoplasmic reticulum stress

Hong‑Shuang Qin, Pei‑Pei Yu, Ying Sun, Dan‑Feng Wang, Xiao‑Fen Deng, Yong‑Li Bao, Jun Song, Lu‑Guo Sun, Zhen‑Bo Song, Yu‑Xin Li
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Published online on: 20 April 2016

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Elevated RNA expression of long non‑coding HOTAIR promotes cell proliferation and predicts a poor prognosis in patients with diffuse large B cell lymphoma

Yuling Yan, Jingyin Han, Zhenqing Li, Honglan Yang, Yanmin Sui, Minglin Wang
Pages: 5125-5131
Published online on: 26 April 2016

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Cordyceps militaris induces tumor cell death via the caspase‑dependent mitochondrial pathway in HepG2 and MCF‑7 cells

Jingjing Song, Yingwu Wang, Meiyu Teng, Shiqiang Zhang, Mengya Yin, Jiahui Lu, Yan Liu, Robert J Lee, Di Wang, Lesheng Teng
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Published online on: 25 April 2016

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Indirect co‑culture of vascular smooth muscle cells with bone marrow mesenchymal stem cells inhibits vascular calcification and downregulates the Wnt signaling pathways

Meng'en Zhu, Xin Fang, Shaoqiong Zhou, Wei Li, Siming Guan
Pages: 5141-5148
Published online on: 25 April 2016

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Astragaloside IV prevents high glucose-induced podocyte apoptosis via downregulation of TRPC6

Xing‑Mei Yao, Yu‑Jun Liu, Yun‑Man Wang, Hao Wang, Bing‑Bing Zhu, Yong‑Ping Liang, Wei‑Guo Yao, Hui Yu, Nian‑Song Wang, Xue‑Mei Zhang, Wen Peng
Pages: 5149-5156
Published online on: 22 April 2016

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Vascular endothelial growth factor induces anti‑Müllerian hormone receptor 2 overexpression in ovarian granulosa cells of in vitro fertilization/intracytoplasmic sperm injection patients

Yanqiu Fang, Xiaodan Lu, Lei Liu, Xiuying Lin, Munan Sun, Jianhua Fu, Shufen Xu, Yan Tan
Pages: 5157-5162
Published online on: 25 April 2016

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Role of RANKL in the regulation of NFATc1 and c‑Src mRNA expression in osteoclast‑like cells

Jifan Fu, You Di Tao, Jian Chen, Yongsheng Zhang, Jianquan He
Pages: 5163-5168
Published online on: 25 April 2016

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Article

Adenovirus encoding XAF-1 and TNF‑α in the same open reading frame efficiently inhibits hepatocellular cancer cells

Kai Li, Xinhong Li, Zhongjun Wu, Liansheng Zheng, Yuqin Cui, Jun Wang, Yin Huang, Zhihong Yan
Pages: 5169-5176
Published online on: 26 April 2016

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Article

Tetrandrine suppresses β‑glucan‑induced macrophage activation via inhibiting NF‑κB, ERK and STAT3 signaling pathways

Jing Xu, Dabiao Liu, Qing Yin, Lanfang Guo
Pages: 5177-5184
Published online on: 25 April 2016

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Shensong Yangxin capsules prevent ischemic arrhythmias by prolonging action potentials and alleviating Ca2+ overload

Yixiu Zhao, Feng Gao, Yong Zhang, Hongtao Wang, Jiuxin Zhu, Liping Chang, Zhimin Du, Yan Zhang
Pages: 5185-5192
Published online on: 28 April 2016

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MicroRNA‑143 targets CD44 to inhibit breast cancer progression and stem cell-like properties

Zhuangqing Yang, Dedian Chen, Jianyun Nie, Shaoqiang Zhou, Jiankui Wang, Qi Tang, Xiaojuan Yang
Pages: 5193-5199
Published online on: 27 April 2016

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TRIM59 is upregulated and promotes cell proliferation and migration in human osteosarcoma

Jinqian Liang, Dan Xing, Zheng Li, Jianxiong Shen, Hong Zhao, Shugang Li
Pages: 5200-5206
Published online on: 25 April 2016

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Article

Changes in mesenchymal stem cells following long-term culture in vitro

Yajun Gu, Tao Li, Yanling Ding, Lingxian Sun, Tao Tu, Wei Zhu, Jiabo Hu, Xiaochun Sun
Pages: 5207-5215
Published online on: 22 April 2016

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p.D1690N sodium voltage-gated channel α subunit 5 mutation reduced sodium current density and is associated with Brugada syndrome

Zhipeng Zeng, Qiang Xie, Yuan Huang, Yuanyuan Zhao, Weihua Li, Zhengrong Huang
Pages: 5216-5222
Published online on: 22 April 2016

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HCV core protein-induced upregulation of microRNA-196a promotes aberrant proliferation in hepatocellular carcinoma by targeting FOXO1

Hao Xu, Guangming Li, Zhanyi Yue, Chengzhong Li
Pages: 5223-5229
Published online on: 22 April 2016

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Synergistically increased ILC2 and Th9 cells in lung tissue jointly promote the pathological process of asthma in mice

Xinyu Ying, Zhaoliang Su, Qingli Bie, Pan Zhang, Huijian Yang, Yumin Wu, Yunyun Xu, Jing Wu, Mengying Zhang, Shengjun Wang, Huaxi Xu
Pages: 5230-5240
Published online on: 25 April 2016

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Article

MicroRNA-199a-5p inhibits tumor proliferation in melanoma by mediating HIF-1α

Xinghua Yang, Shaorong Lei, Jianhong Long, Xiaojin Liu, Qizhen Wu
Pages: 5241-5247
Published online on: 28 April 2016

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Article

Neuroprotective effects of resveratrol against traumatic brain injury in rats: Involvement of synaptic proteins and neuronal autophagy

Yan Feng, Ying Cui, Jun‑Ling Gao, Ran Li, Xiao‑Hua Jiang, Yan‑Xia Tian, Kai‑Jie Wang, Ming‑Hang Li, Hong‑Ao Zhang, Jian‑Zhong Cui
Pages: 5248-5254
Published online on: 28 April 2016

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Article

Knockdown of RHOC by shRNA suppresses invasion and migration of cholangiocellular carcinoma cells via inhibition of MMP2, MMP3, MMP9 and epithelial-mesenchymal transition

Haixia Yang, Jun Liang, Jiupeng Zhou, Jianqiang Mi, Ke Ma, Yangwei Fan, Jing Ning, Chuying Wang, Xin Wei, Enxiao Li
Pages: 5255-5261
Published online on: 22 April 2016

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Article

Apelin-13 protects against myocardial infarction-induced myocardial fibrosis

Xuemin Zhang, Wenyu Hu, Feng Feng, Jian Xu, Fang Wu
Pages: 5262-5268
Published online on: 22 April 2016

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Article

Heme oxygenase‑1 protects H2O2‑insulted glomerular mesangial cells from excessive autophagy

Jia Xu, Jinshun Li, Jinhua Wang, Yanchun Chi, Kun Zhang, Rui Cui
Pages: 5269-5275
Published online on: 25 April 2016

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Article

Oleanolic acid inhibits colorectal cancer angiogenesis in vivo and in vitro via suppression of STAT3 and Hedgehog pathways

Li Li, Jiumao Lin, Guodong Sun, Lihui Wei, Aling Shen, Mingyue Zhang, Jun Peng
Pages: 5276-5282
Published online on: 22 April 2016

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Article

Expression and clinical significance of aquaglyceroporins in human hepatocellular carcinoma

Xiao‑Feng Chen, Chuan‑Fei Li, Lin Lü, Zhe‑Chuan Mei
Pages: 5283-5289
Published online on: 25 April 2016

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Article

HAT inhibitor, garcinol, exacerbates lipopolysaccharide‑induced inflammation in vitro and in vivo

Bin Wang, Ling Lin, Qing Ai, Tao Zeng, Pu Ge, Li Zhang
Pages: 5290-5296
Published online on: 26 April 2016

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Article

Association between microRNA polymorphisms and the risk of inflammatory bowel disease

Min Zhu, Diangeng Li, Meiling Jin, Mingyang Li
Pages: 5297-5308
Published online on: 21 April 2016

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Article

Ursolic acid prevents augmented peripheral inflammation and inflammatory hyperalgesia in high-fat diet-induced obese rats by restoring downregulated spinal PPARα

Yanan Zhang, Chengwei Song, Haiou Li, Jingdong Hou, Dongliang Li
Pages: 5309-5316
Published online on: 22 April 2016

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Effects of bone marrow mesenchymal stem cells on the cardiac function and immune system of mice with endotoxemia

Yuanfan Wu, Jing Zhou, Liqing Bi, Min Huang, Yi Han, Qian Zhang, Dongmei Zhu, Suming Zhou
Pages: 5317-5325
Published online on: 20 April 2016

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Article

Ibuprofen attenuates nephropathy in streptozotocin‑induced diabetic rats

Yao‑Wu Liu, Xia Zhu, Ya‑Qin Cheng, Qian Lu, Fan Zhang, Hao Guo, Xiao‑Xing Yin
Pages: 5326-5334
Published online on: 20 April 2016

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Article

MicroRNA‑451 protects against cardiomyocyte anoxia/reoxygenation injury by inhibiting high mobility group box 1 expression

Jing Xie, Xiaorong Hu, Chunfeng Yi, Gangying Hu, Xiaoya Zhou, Hong Jiang
Pages: 5335-5341
Published online on: 26 April 2016

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Rhizoma Dioscoreae extract protects against alveolar bone loss by regulating the cell cycle: A predictive study based on the protein‑protein interaction network

Zhi‑Guo Zhang, Chang‑Heng Song, Fang‑Zhen Zhang, Yan‑Jing Chen, Li‑Hua Xiang, Gary Guishan Xiao, Da‑Hong Ju
Pages: 5342-5348
Published online on: 25 April 2016

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Article

CD4+ T cell responses in Balb/c mice with food allergy induced by trinitrobenzene sulfonic acid and ovalbumin

Chen‑Yi Sun, Jie Bai, Tian‑Yong Hu, Bao‑Hui Cheng, Li Ma, Xiao‑Qin Fan, Ping‑Chang Yang, Peng‑Yuan Zheng, Zhi‑Qiang Liu
Pages: 5349-5357
Published online on: 21 April 2016

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Article

TLR2/NFκB signalling regulates endogenous IL-6 release from marrow-derived mesenchymal stromal cells to suppress the apoptosis of PC12 cells injured by oxygen and glucose deprivation

Xia Shi, Jingjing Liu, Ting Yang, Yun Zhang, Tingyu Li, Jie Chen
Pages: 5358-5364
Published online on: 22 April 2016

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Article

Roles of SHARP1 in thyroid cancer

Zun‑Hai Zhou, Bo Wang, Xiao‑Bing Cheng, Xuan‑E Zhang, Jian Tang, Wen‑Jia Tang, Lei Gu
Pages: 5365-5371
Published online on: 25 April 2016

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Combined treatment with vitamin E and gefitinib has synergistic effects to inhibit TGF-β1-induced renal fibroblast proliferation

Giou‑Teng Yiang, Jen‑Ni Chen, Pei‑Shiuan Lin, Hsiao‑Chun Liu, Shu‑Ying Chen, Chyou‑Wei Wei
Pages: 5372-5378
Published online on: 21 April 2016

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NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-κB pathway

Chun‑Yan Xu, Meng‑Bin Qin, Lin Tan, Shi‑Quan Liu, Jie‑An Huang
Pages: 5379-5385
Published online on: 22 April 2016

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Tumor suppressor miR-149-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma

Lu Jin, Yifan Li, Jiaju Liu, Shangqi Yang, Yaoting Gui, Xiangming Mao, Guohui Nie, Yongqing Lai
Pages: 5386-5392
Published online on: 28 April 2016

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July-2026 Volume 34 Issue 1

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Article Number: 211
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[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

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Article Number: 207
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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

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Article Number: 202
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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

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Article Number: 200
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Article Number: 199
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Article Number: 198
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Article Number: 197
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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
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Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
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Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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August-2026 Volume 34 Issue 2

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CiteScore: 7.3

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
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Review Open Access

Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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Article Open Access

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Review Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Review Open Access

Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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