|
1
|
Pye SR, Huhtaniemi IT, Finn JD, Lee DM,
O'Neill TW, Tajar A, Bartfai G, Boonen S, Casanueva FF, Forti G, et
al: Late-onset hypogonadism and mortality in aging men. J Clin
Endocrinol Metab. 99:1357–1366. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lee SY, Gong EY, Hong CY, Kim KH, Han JS,
Ryu JC, Chae HZ, Yun CH and Lee K: ROS inhibit the expression of
testicular steroidogenic enzyme genes via the suppression of Nur77
trans-activation. Free Radic Biol Med. 47:1591–1600. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Sun AY and Chen YM: Oxidative stress and
neurodegenerative disorders. J Biomed Sci. 5:401–414. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Gius D and Spitz DR: Redox signaling in
cancer biology. Antioxid Redox Signal. 8:1249–1252. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Wang JY, Lee YJ, Chou MC, Chang R, Chiu
CH, Liang YJ and Wu LS: Astaxanthin protects steroidogenesis from
hydrogen peroxide-induced oxidative stress in mouse leydig cells.
Mar Drugs. 13:1375–1388. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Diemer T, Allen JA, Hales KH and Hales DB:
Reactive oxygen disrupts mitochondria in MA-10 tumor Leydig cells
and inhibits steroidogenic acute regulatory (StAR) protein and
steroido-genesis. Endocrinology. 144:2882–2891. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Tsai SC, Lu CC, Lin CS and Wang PS:
Antisteroidogenic actions of hydrogen peroxide on rat Leydig cells.
J Cell Biochem. 90:1276–1286. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Li WR, Chen L, Chang ZJ, Xin H, Liu T,
Zhang YQ, Li GY, Zhou F, Gong YQ, Gao ZZ and Xin ZC: Autophagic
deficiency is relatedto steroidogenic decline in aged rat Leydig
cells. Asian J Androl. 13:881–888. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhao F and Wang Q: The protective effect
of peroxiredoxin II on oxidative stress induced apoptosis in
pancreatic β-cells. Cell Biosci. 2:222012. View Article : Google Scholar
|
|
10
|
Lu W, Fu Z, Wang H, Feng J, Wei J and Guo
J: Peroxiredoxin 2 is upregulated in colorectal cancer and
contributes to colorectal cancer cells' survival by protecting
cells from oxidative stress. Mol Cell Biochem. 387:261–270. 2014.
View Article : Google Scholar
|
|
11
|
Lu W, Fu Z, Wang H, Feng J, Wei J and Guo
J: Peroxiredoxin 2 knockdown by RNA interference inhibits the
growth of colorectal cancer cells by downregulating Wnt/β-catenin
signaling. Cancer Lett. 343:190–199. 2014. View Article : Google Scholar
|
|
12
|
Yang S, Luo A, Hao X, Lai Z, Ding T, Ma X,
Mayinuer M, Shen W, Wang X, Lu Y, et al: Peroxiredoxin 2 inhibits
granulosa cell apoptosis during follicle atresia through the NFKB
pathway in mice. Biol Reprod. 84:1182–1189. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
National Research Council: Guide for the
Care and Use of Laboratory Animals. 8th edition. National Academies
Press; Washington, DC: 1996
|
|
14
|
Svechnikov KV, Sultana T and Söder O:
Age-dependent stimulation of Leydig cell steroidogenesis by
interleukin-1 isoforms. Mol Cell Endocrinol. 182:193–201. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Payne AH, Downing JR and Wong KL:
Luteinizing hormone receptors and testosterone synthesis in two
distinct populations of Leydig cells. Endocrinology. 106:1424–1429.
1980. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
17
|
Kruger NJ: The Bradford method for protein
quantitation. Methods in Molecular Biology. Walker JM: 32. Humana
Press; Totowa, NJ: pp. 9–15. 1994
|
|
18
|
Corona G, Rastrelli G, Vignozzi L,
Mannucci E and Maggi M: How to recognize late-onset hypogonadism in
men with sexual dysfunction. Asian J Androl. 14:251–259. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Arianayagam R, Arianayagam M, McGrath S
and Rashid P: Androgen deficiency in the aging man. Aust Fam
Physician. 39:752–755. 2010.PubMed/NCBI
|
|
20
|
Wylie K and Froggatt N: Late onset
hypogonadism, sexuality and fertility. Hum Fertil (Camb).
13:126–133. 2010. View Article : Google Scholar
|
|
21
|
Bassil N and Morley JE: Late-life onset
hypogonadism: A review. Clin Geriatr Med. 26:197–222. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Hall PF: Testicular steroidogenesis:
Organization and regulation. The Physiology of Reproduction. Knobil
E and Neill JD: Raven Press; New York: pp. 1335–1362. 1994
|
|
23
|
Hornsby PJ and Crivello JF: The role of
lipid peroxidation and biological antioxidants in the function of
the adrenal cortex. Part 2. Mol Cell Endocrinol. 30:123–147. 1983.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Chen H, Cangello D, Benson S, Folmer J,
Zhu H, Trush MA and Zirkin BR: Age-related increase in
mitochondrial superoxide generation in the testosterone-producing
cells of Brown Norway rat testes: Relationship to reduced
steroidogenic function? Exp Gerontol. 36:1361–1373. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Gautam DK, Misro MM, Chaki SP and Sehgal
N: H2O at physiological concentrations modulates Leydig
cell function inducing oxidative stress and apoptosis. Apoptosis.
11:39–46. 2006. View Article : Google Scholar
|
|
26
|
Woo HA, Chae HZ, Hwang SC, Yang KS, Kang
SW, Kim K and Rhee SG: Reversing the inactivation of peroxiredoxins
caused by cysteine sulfinic acid formation. Science. 300:653–656.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhao W, Fan GC, Zhang ZG, Bandyopadhyay A,
Zhou X and Kranias EG: Protection of peroxiredoxin II on oxidative
stress-induced cardiomyocyte death and apoptosis. Basic Res
Cardiol. 104:377–389. 2009. View Article : Google Scholar :
|
